Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT2 | Others | Unspecified | Potency | 3.5 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 17.4 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 61130.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 68589.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 76802.3 | nM | PubChem BioAssay data set |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC15162 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.8298 | Intermediate Similarity | NPC131623 |
0.7917 | Intermediate Similarity | NPC329773 |
0.7872 | Intermediate Similarity | NPC100445 |
0.7755 | Intermediate Similarity | NPC214584 |
0.7755 | Intermediate Similarity | NPC26906 |
0.7692 | Intermediate Similarity | NPC274396 |
0.7692 | Intermediate Similarity | NPC39068 |
0.76 | Intermediate Similarity | NPC35519 |
0.76 | Intermediate Similarity | NPC179169 |
0.76 | Intermediate Similarity | NPC181255 |
0.76 | Intermediate Similarity | NPC306195 |
0.76 | Intermediate Similarity | NPC157781 |
0.7447 | Intermediate Similarity | NPC87439 |
0.7381 | Intermediate Similarity | NPC328441 |
0.7333 | Intermediate Similarity | NPC188596 |
0.7255 | Intermediate Similarity | NPC68014 |
0.7255 | Intermediate Similarity | NPC71506 |
0.7255 | Intermediate Similarity | NPC294358 |
0.7255 | Intermediate Similarity | NPC40417 |
0.7255 | Intermediate Similarity | NPC177112 |
0.7222 | Intermediate Similarity | NPC278550 |
0.7174 | Intermediate Similarity | NPC180871 |
0.7174 | Intermediate Similarity | NPC46248 |
0.7174 | Intermediate Similarity | NPC249801 |
0.7174 | Intermediate Similarity | NPC194586 |
0.7174 | Intermediate Similarity | NPC108494 |
0.7174 | Intermediate Similarity | NPC51758 |
0.7174 | Intermediate Similarity | NPC88079 |
0.7174 | Intermediate Similarity | NPC209279 |
0.7174 | Intermediate Similarity | NPC67761 |
0.7174 | Intermediate Similarity | NPC68889 |
0.717 | Intermediate Similarity | NPC227135 |
0.7143 | Intermediate Similarity | NPC323153 |
0.7083 | Intermediate Similarity | NPC165651 |
0.7083 | Intermediate Similarity | NPC24824 |
0.7083 | Intermediate Similarity | NPC210560 |
0.7037 | Intermediate Similarity | NPC264779 |
0.7018 | Intermediate Similarity | NPC41160 |
0.6964 | Remote Similarity | NPC5698 |
0.6897 | Remote Similarity | NPC174956 |
0.6852 | Remote Similarity | NPC67508 |
0.6852 | Remote Similarity | NPC84824 |
0.6852 | Remote Similarity | NPC281590 |
0.6842 | Remote Similarity | NPC66020 |
0.6842 | Remote Similarity | NPC135648 |
0.6792 | Remote Similarity | NPC192962 |
0.6786 | Remote Similarity | NPC189290 |
0.6786 | Remote Similarity | NPC10017 |
0.6786 | Remote Similarity | NPC474769 |
0.6786 | Remote Similarity | NPC41180 |
0.6786 | Remote Similarity | NPC152438 |
0.678 | Remote Similarity | NPC300593 |
0.6727 | Remote Similarity | NPC24443 |
0.6724 | Remote Similarity | NPC194208 |
0.6724 | Remote Similarity | NPC63111 |
0.6724 | Remote Similarity | NPC79576 |
0.6724 | Remote Similarity | NPC225342 |
0.6724 | Remote Similarity | NPC282694 |
0.6667 | Remote Similarity | NPC184049 |
0.6667 | Remote Similarity | NPC252978 |
0.6667 | Remote Similarity | NPC52431 |
0.6667 | Remote Similarity | NPC99480 |
0.6667 | Remote Similarity | NPC469321 |
0.6667 | Remote Similarity | NPC286752 |
0.6667 | Remote Similarity | NPC310228 |
0.6667 | Remote Similarity | NPC168518 |
0.6667 | Remote Similarity | NPC64123 |
0.6667 | Remote Similarity | NPC105780 |
0.6667 | Remote Similarity | NPC475931 |
0.661 | Remote Similarity | NPC81615 |
0.6607 | Remote Similarity | NPC52012 |
0.6557 | Remote Similarity | NPC267027 |
0.6557 | Remote Similarity | NPC279434 |
0.6557 | Remote Similarity | NPC476406 |
0.6552 | Remote Similarity | NPC40206 |
0.6552 | Remote Similarity | NPC469694 |
0.6552 | Remote Similarity | NPC252809 |
0.6552 | Remote Similarity | NPC240506 |
0.6545 | Remote Similarity | NPC130209 |
0.6545 | Remote Similarity | NPC218525 |
0.6545 | Remote Similarity | NPC148216 |
0.6545 | Remote Similarity | NPC148163 |
0.6491 | Remote Similarity | NPC475830 |
0.6491 | Remote Similarity | NPC181872 |
0.6491 | Remote Similarity | NPC155025 |
0.6452 | Remote Similarity | NPC73603 |
0.6441 | Remote Similarity | NPC207007 |
0.6441 | Remote Similarity | NPC68679 |
0.6441 | Remote Similarity | NPC15152 |
0.6441 | Remote Similarity | NPC210346 |
0.6441 | Remote Similarity | NPC321867 |
0.6429 | Remote Similarity | NPC179024 |
0.6415 | Remote Similarity | NPC48162 |
0.6415 | Remote Similarity | NPC251335 |
0.64 | Remote Similarity | NPC76976 |
0.6393 | Remote Similarity | NPC308844 |
0.6393 | Remote Similarity | NPC469326 |
0.6393 | Remote Similarity | NPC261782 |
0.6393 | Remote Similarity | NPC205618 |
0.6393 | Remote Similarity | NPC471200 |
0.6383 | Remote Similarity | NPC56917 |
0.6379 | Remote Similarity | NPC122239 |
0.6379 | Remote Similarity | NPC278202 |
0.6333 | Remote Similarity | NPC50435 |
0.6333 | Remote Similarity | NPC474480 |
0.6327 | Remote Similarity | NPC269862 |
0.6304 | Remote Similarity | NPC34873 |
0.6304 | Remote Similarity | NPC40434 |
0.6296 | Remote Similarity | NPC208638 |
0.629 | Remote Similarity | NPC197089 |
0.6271 | Remote Similarity | NPC99487 |
0.625 | Remote Similarity | NPC9942 |
0.625 | Remote Similarity | NPC223604 |
0.625 | Remote Similarity | NPC329686 |
0.625 | Remote Similarity | NPC476431 |
0.625 | Remote Similarity | NPC304690 |
0.625 | Remote Similarity | NPC232247 |
0.625 | Remote Similarity | NPC476604 |
0.625 | Remote Similarity | NPC74722 |
0.625 | Remote Similarity | NPC251666 |
0.623 | Remote Similarity | NPC219940 |
0.623 | Remote Similarity | NPC309300 |
0.623 | Remote Similarity | NPC225415 |
0.623 | Remote Similarity | NPC101128 |
0.6226 | Remote Similarity | NPC474460 |
0.6207 | Remote Similarity | NPC226848 |
0.6207 | Remote Similarity | NPC329819 |
0.619 | Remote Similarity | NPC101307 |
0.619 | Remote Similarity | NPC472255 |
0.619 | Remote Similarity | NPC472253 |
0.619 | Remote Similarity | NPC88454 |
0.619 | Remote Similarity | NPC278895 |
0.619 | Remote Similarity | NPC136813 |
0.619 | Remote Similarity | NPC117607 |
0.6182 | Remote Similarity | NPC165755 |
0.6167 | Remote Similarity | NPC274704 |
0.6167 | Remote Similarity | NPC64971 |
0.6167 | Remote Similarity | NPC475251 |
0.6154 | Remote Similarity | NPC475728 |
0.614 | Remote Similarity | NPC141699 |
0.614 | Remote Similarity | NPC48891 |
0.614 | Remote Similarity | NPC210316 |
0.6136 | Remote Similarity | NPC283682 |
0.6129 | Remote Similarity | NPC238352 |
0.6129 | Remote Similarity | NPC250836 |
0.6129 | Remote Similarity | NPC61503 |
0.6129 | Remote Similarity | NPC19569 |
0.6129 | Remote Similarity | NPC258595 |
0.6129 | Remote Similarity | NPC477009 |
0.6094 | Remote Similarity | NPC471238 |
0.6094 | Remote Similarity | NPC94192 |
0.6094 | Remote Similarity | NPC2648 |
0.6087 | Remote Similarity | NPC177022 |
0.6078 | Remote Similarity | NPC108441 |
0.6078 | Remote Similarity | NPC77550 |
0.6066 | Remote Similarity | NPC211291 |
0.6066 | Remote Similarity | NPC473759 |
0.6066 | Remote Similarity | NPC474155 |
0.6066 | Remote Similarity | NPC473508 |
0.6066 | Remote Similarity | NPC133368 |
0.6066 | Remote Similarity | NPC279200 |
0.6061 | Remote Similarity | NPC471272 |
0.6061 | Remote Similarity | NPC475077 |
0.6061 | Remote Similarity | NPC471660 |
0.6038 | Remote Similarity | NPC62755 |
0.6034 | Remote Similarity | NPC121034 |
0.6034 | Remote Similarity | NPC7491 |
0.6034 | Remote Similarity | NPC101285 |
0.6034 | Remote Similarity | NPC27853 |
0.6034 | Remote Similarity | NPC165808 |
0.6034 | Remote Similarity | NPC65786 |
0.6034 | Remote Similarity | NPC13789 |
0.6032 | Remote Similarity | NPC149680 |
0.6032 | Remote Similarity | NPC103734 |
0.6032 | Remote Similarity | NPC469328 |
0.6032 | Remote Similarity | NPC202017 |
0.6032 | Remote Similarity | NPC230107 |
0.6032 | Remote Similarity | NPC272125 |
0.6 | Remote Similarity | NPC144891 |
0.6 | Remote Similarity | NPC162109 |
0.6 | Remote Similarity | NPC329989 |
0.6 | Remote Similarity | NPC469914 |
0.6 | Remote Similarity | NPC144647 |
0.6 | Remote Similarity | NPC471560 |
0.6 | Remote Similarity | NPC239373 |
0.6 | Remote Similarity | NPC35756 |
0.6 | Remote Similarity | NPC210323 |
0.6 | Remote Similarity | NPC472947 |
0.597 | Remote Similarity | NPC476609 |
0.5968 | Remote Similarity | NPC290367 |
0.5968 | Remote Similarity | NPC234767 |
0.5968 | Remote Similarity | NPC144650 |
0.5968 | Remote Similarity | NPC107540 |
0.5968 | Remote Similarity | NPC68656 |
0.5965 | Remote Similarity | NPC474644 |
0.5938 | Remote Similarity | NPC161612 |
0.5938 | Remote Similarity | NPC476650 |
0.5938 | Remote Similarity | NPC33583 |
0.5938 | Remote Similarity | NPC139207 |
0.5938 | Remote Similarity | NPC197805 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC15162 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6545 | Remote Similarity | NPD342 | Phase 1 |
0.6441 | Remote Similarity | NPD368 | Approved |
0.6346 | Remote Similarity | NPD9410 | Clinical (unspecified phase) |
0.6078 | Remote Similarity | NPD386 | Approved |
0.6078 | Remote Similarity | NPD388 | Approved |
0.5902 | Remote Similarity | NPD834 | Approved |
0.5902 | Remote Similarity | NPD835 | Approved |
0.5882 | Remote Similarity | NPD4785 | Approved |
0.5882 | Remote Similarity | NPD4784 | Approved |
0.5849 | Remote Similarity | NPD622 | Approved |
0.5821 | Remote Similarity | NPD4243 | Approved |
0.5806 | Remote Similarity | NPD832 | Approved |
0.5806 | Remote Similarity | NPD833 | Approved |
0.5781 | Remote Similarity | NPD7331 | Phase 2 |
0.5741 | Remote Similarity | NPD3173 | Approved |
0.5738 | Remote Similarity | NPD1145 | Discontinued |
0.5672 | Remote Similarity | NPD7144 | Approved |
0.5672 | Remote Similarity | NPD7143 | Approved |
0.5667 | Remote Similarity | NPD570 | Approved |
0.566 | Remote Similarity | NPD385 | Approved |
0.566 | Remote Similarity | NPD384 | Approved |
0.5652 | Remote Similarity | NPD6926 | Approved |
0.5652 | Remote Similarity | NPD6924 | Approved |
0.5625 | Remote Similarity | NPD7341 | Phase 2 |
0.5614 | Remote Similarity | NPD3172 | Approved |
PubChem CID   | 29096 |
ChEMBL   | CHEMBL3184487 |
ZINC   |
Molecular Weight:   | 156.15 |
ALogP:   | 1.1979 |
MLogP:   | 2.45 |
XLogP:   | 3.573 |
# Rotatable Bonds:   | 9 |
Polar Surface Area:   | 20.23 |
# H-Bond Aceptor:   | 1 |
# H-Bond Donor:   | 1 |
# Rings:   | 0 |
# Heavy Atoms:   | 11 |