Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC243509 BACE1 2 Median: 61150
Range: 30500 to 91800
IC50 PMID: 19939683
PMID: 22222157
NPC243509 GAA 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC243509 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243509 ABCB1 1 28000 IC50 DOI: 10.1039/C4MD00196F
NPC88445 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC88445 LMNA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96286 ALOX5 1 36200 IC50 PMID: 9544564
NPC96286 ABCB1 1 34000 IC50 DOI: 10.1039/C4MD00196F
NPC96286 ALDH1A1 2 Median: 36426.1
Range: 28183.8 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC96286 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294852 CYP1A1 1 10973 IC50 PMID: 20696580