Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC201844 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
| NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
| NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
| NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
| NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
| NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
| NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
| NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
| NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
| NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
| NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
| NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
| NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC218866 | EPHX2 | 1 | 41100 | IC50 |
PMID: 26372074 |
| NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
| NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
| NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
| NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279026 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279026 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC279026 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC279026 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC70622 | EPHX2 | 1 | 26800 | IC50 |
PMID: 26372074 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | CASP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | CYP19A1 | 1 | 28200 | IC50 |
PMID: 16643058 |
| NPC91495 | BLM | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | KDM4E | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | TDP1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | LMNA | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC91495 | HPGD | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC192638 | TOP2A | 1 | 10400 | IC50 |
PMID: 11754608 |
| NPC201844 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
| NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
| NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
| NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
| NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
| NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
| NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
| NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
| NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
| NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
| NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC293378 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |