Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC136330 CTSD 1 42300 IC50 DOI: 10.1007/s00044-012-0397-z
NPC136330 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 HPGD 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 ABCB1 2 Median: 44800
Range: 15500 to 74100
IC50 PMID: 12130727
PMID: 12130727
NPC136330 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 MAPK1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247871 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC255817 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC255817 SMN1;SMN2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC255817 HSD17B10 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC255817 CYP2D6 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC255817 ALDH1A1 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862