Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100079 RAB9A 1 46109.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HIF1A 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 TSHR 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2D6 1 25118.86 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC100079 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HSD17B10 2 Median: 22535.75
Range: 19952.6 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALDH1A1 2 Median: 19118.05
Range: 15848.9 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPT 4 Median: 15848.9
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC109637 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC109637 CASP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC109637 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC109637 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC109637 CASP7 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 ATM 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 KMT2A 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC193484 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC193484 ALDH1A1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC263670 DPP4 1 33110 IC50 DOI: 10.1039/C0MD00245C
NPC308267 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC308267 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 RAB9A 1 46109.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 RGS12 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 MAPK1 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 BAD 1 19000 IC50 PMID: 18925736
NPC46451 MAPT 2 Median: 22983.3
Range: 17782.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 TERT 1 37000 IC50 PMID: 22336246
NPC67978 KMT2A 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC77572 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALOX12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 NFKB1 2 Median: 11220.2
Range: 11220.2 to 11220.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC109637 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC109637 TP53 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC109637 MAPT 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC193484 TP53 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC286608 ALDH1A1 1 12589.3 Potency PMID: 7807120
NPC308267 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 HPGD 2 Median: 21154.6
Range: 14125.4 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 TSHR 4 Median: 18854.1
Range: 12589.3 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 SMN1;SMN2 2 Median: 16803.7
Range: 11220.2 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 TP53 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 HPGD 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862