Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156654 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELL 1 27600 IC50 PMID: 17302397
NPC225710 GAPDH 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 MAPK1 2 Median: 23753.05
Range: 22387.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELP 1 19100 IC50 PMID: 17302397
NPC225710 SMN1;SMN2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260491 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260491 RECQL 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 RECQL 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 MMP13 1 34600 IC50 PMID: 22658537
NPC36835 ADORA3 1 34100 Ki PMID: 8576921
NPC36835 MMP3 1 33910 IC50 PMID: 22658537
NPC36835 MMP9 1 32020 IC50 PMID: 22658537
NPC36835 GMNN 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC36835 MMP2 1 22620 IC50 PMID: 22658537
NPC36835 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51443 HBB 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51443 CYP3A4 4 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51443 LMNA 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51443 CYP2C9 2 Median: 22535.75
Range: 19952.6 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51443 AMY1A;AMY1B;AMY1C 1 19600 IC50 PMID: 18507367
NPC51443 CASP1 2 Median: 20483.9
Range: 15848.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51443 CASP7 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51443 SYK 1 15000 IC50 PMID: 22257213
NPC51443 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 FUT4 1 14000 IC50 DOI: 10.1039/C4MD00086B
NPC260491 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51443 ALDH1A1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862