Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC101475 | AKR1B10 | 1 | 30000 | IC50 |
PMID: 21561086 |
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC178134 | CYP2C9 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CYP2C19 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | THRB | 2 |
Median: 32464.8 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CARM1 | 1 | 25000 | IC50 |
DOI: 10.1039/C1MD00199J |
| NPC178134 | GSR | 1 | 22800 | IC50 |
PMID: 19015351 |
| NPC178134 | EPHX2 | 1 | 20700 | IC50 |
PMID: 24679441 |
| NPC178134 | ATM | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC181225 | PTPRF | 1 | 35900 | IC50 |
PMID: 21453996 |
| NPC192744 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC264317 | POLB | 2 |
Median: 44925 Range: 43600 to 46250 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC264317 | GLI1 | 2 |
Median: 32000 Range: 32000 to 32000 |
IC50 |
PMID: 18842418 PMID: 19309080 |
| NPC26960 | PTPN1 | 1 | 32600 | IC50 |
PMID: 25497963 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC54321 | PTPN1 | 1 | 16820 | IC50 |
PMID: 24224843 |
| NPC75844 | ALDH1A1 | 1 | 37650.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC75844 | MTOR | 1 | 23280.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC178134 | CA5B | 1 | 12700 | Ki |
PMID: 20185318 |
| NPC178134 | MAPT | 8 |
Median: 21169.9 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | TP53 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | KMT2A | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CA3 | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC181225 | ACP1 | 2 |
Median: 22000 Range: 13400 to 30600 |
IC50 |
PMID: 21453996 PMID: 21453996 |
| NPC264317 | AKR1B1 | 1 | 11000 | IC50 |
PMID: 21561086 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC75844 | HBB | 3 |
Median: 25118.9 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |