Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC113733 POLB 2 Median: 51840
Range: 43400 to 60280
IC50 PMID: 14640519
PMID: 18343122
NPC131885 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC232692 CA13 1 29300 Ki PMID: 22892213
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC244799 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC244799 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC244799 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC244799 HPGD 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC244799 CA12 1 18200 Ki PMID: 22892213
NPC34770 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 TP53 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50720 CA13 1 45000 Ki PMID: 22892213
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC34770 HPGD 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 KDM4E 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213