Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC126029 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC173637 PIM2 1 25000 IC50 PMID: 18163587
NPC173637 L3MBTL1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC173637 XDH 1 14740 IC50 PMID: 12444671
NPC219876 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 PTGS1 2 Median: 58350
Range: 36700 to 80000
IC50 PMID: 11858749
PMID: 16038536
NPC219876 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 BLM 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 RECQL 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 MAPT 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 APEX1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELL 1 27600 IC50 PMID: 17302397
NPC225710 GAPDH 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 MAPK1 2 Median: 23753.05
Range: 22387.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELP 1 19100 IC50 PMID: 17302397
NPC225710 SMN1;SMN2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73855 MPI 1 30965 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC73855 RECQL 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73855 ALDH1A1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73855 MAPT 2 Median: 16815.85
Range: 15848.9 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC126029 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC126029 KDM4E 2 Median: 16803.7
Range: 11220.2 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 KDM4E 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 POLB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 FUT4 1 14000 IC50 DOI: 10.1039/C4MD00086B