Plant ID: NPO27520
Plant Latin Name: Casuarina Equisetifolia
Taxonomy Genus: Casuarina
Taxonomy Family: Casuarinaceae
NCBI TaxonomyDB:
3523
Plant-of-the-World-Online:
n.a.
Australia; Philippines; Indonesia; India; Malaysia; Thailand
Ingredient ID: NPC98745
Ingredient ID: NPC80241
Ingredient ID: NPC72392
Ingredient ID: NPC64434
Ingredient ID: NPC62602
Ingredient ID: NPC62203
Ingredient ID: NPC49603
Ingredient ID: NPC38468
Ingredient ID: NPC32411
Ingredient ID: NPC316926
Ingredient ID: NPC312507
Ingredient ID: NPC305766
Ingredient ID: NPC264145
Ingredient ID: NPC245665
Ingredient ID: NPC242885
Ingredient ID: NPC226753
Ingredient ID: NPC221850
Ingredient ID: NPC198179
Ingredient ID: NPC197396
Ingredient ID: NPC184049
Ingredient ID: NPC177520
Ingredient ID: NPC174459
Ingredient ID: NPC161249
Ingredient ID: NPC147616
Ingredient ID: NPC137167
Ingredient ID: NPC11952
Ingredient ID: NPC104077
Ingredient ID: NPC101748
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Oxidoreductase | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | P37059 | CHEMBL2789 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials |
---|
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B2
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
HSD17B2
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
HSD17B2
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
HSD17B2
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
HSD17B2
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
HSD17B2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B2
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
HSD17B2
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
HSD17B2
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
HSD17B2
|