Collective Molecular Activities of the Plant: Allium Schoenoprasum
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PLANiTS DNA barcode
Taxonomic Information
Plant ID: NPO22233
Plant Latin Name: Allium Schoenoprasum
Taxonomy Genus: Allium
Taxonomy Family: Amaryllidaceae
Plant External Links:
NCBI TaxonomyDB:
74900
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary
Overview of Ingredients
59 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
50 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
47 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC94167
Ingredient ID: NPC93888
Ingredient ID: NPC85813
Ingredient ID: NPC81010
Ingredient ID: NPC62045
Ingredient ID: NPC60151
Ingredient ID: NPC58530
Ingredient ID: NPC55412
Ingredient ID: NPC491218
Ingredient ID: NPC489907
Ingredient ID: NPC424
Ingredient ID: NPC328447
Ingredient ID: NPC317120
Ingredient ID: NPC313955
Ingredient ID: NPC294548
Ingredient ID: NPC290319
Ingredient ID: NPC281686
Ingredient ID: NPC279121
Ingredient ID: NPC277130
Ingredient ID: NPC272614
Ingredient ID: NPC269919
Ingredient ID: NPC261831
Ingredient ID: NPC254764
Ingredient ID: NPC252929
Ingredient ID: NPC242580
Ingredient ID: NPC237812
Ingredient ID: NPC226453
Ingredient ID: NPC226027
Ingredient ID: NPC219143
Ingredient ID: NPC213876
Ingredient ID: NPC208793
Ingredient ID: NPC20791
Ingredient ID: NPC203468
Ingredient ID: NPC199581
Ingredient ID: NPC199072
Ingredient ID: NPC189891
Ingredient ID: NPC189436
Ingredient ID: NPC187770
Ingredient ID: NPC185755
Ingredient ID: NPC181584
Ingredient ID: NPC17810
Ingredient ID: NPC174246
Ingredient ID: NPC1682
Ingredient ID: NPC167400
Ingredient ID: NPC152451
Ingredient ID: NPC150950
Ingredient ID: NPC1502
Ingredient ID: NPC147983
Ingredient ID: NPC137958
Ingredient ID: NPC137739
Ingredient ID: NPC136014
Ingredient ID: NPC130683
Ingredient ID: NPC126681
Ingredient ID: NPC125062
Ingredient ID: NPC116775
Ingredient ID: NPC11433
Ingredient ID: NPC112890
Ingredient ID: NPC109034
Ingredient ID: NPC100380
Classification of Human Proteins Collectively Targeted by the Plant
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
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Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
| Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
| Therapeutic Target | Enzyme | AKR1C3 | Aldo-keto-reductase family 1 member C3 | P42330 | CHEMBL4681 |
| Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
| Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
| Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
| Therapeutic Target | Fatty acid binding protein family | FABP5 | Fatty acid binding protein epidermal | Q01469 | CHEMBL3674 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK1 | Glutamate receptor ionotropic kainate 1 | P39086 | CHEMBL1918 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK3 | Glutamate receptor ionotropic kainate 3 | Q13003 | CHEMBL3684 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK5 | Glutamate receptor ionotropic kainate 5 | Q16478 | CHEMBL2675 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIA4 | Glutamate receptor ionotropic, AMPA 4 | P48058 | CHEMBL3190 |
| Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Membrane receptor | APP | Beta amyloid A4 protein | P05067 | CHEMBL2487 |
| Therapeutic Target | Metallo protease | MMP12 | Matrix metalloproteinase 12 | P39900 | CHEMBL4393 |
| Therapeutic Target | Nuclear hormone receptor subfamily 1 | PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 | CHEMBL239 |
| Therapeutic Target | Oxidoreductase | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | P37059 | CHEMBL2789 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
| Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
| Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
| Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
| Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
| Therapeutic Target | Protein Kinase | MKNK2 | MAP kinase signal-integrating kinase 2 | Q9HBH9 | CHEMBL4204 |
| Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
| Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
| Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
| Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
| Therapeutic Target | Protein Kinase | MKNK1 | MAP kinase-interacting serine/threonine-protein kinase MNK1 | Q9BUB5 | CHEMBL4718 |
| Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
| Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
| Therapeutic Target | Protein Kinase | MAPK1 | MAP kinase ERK2 | P28482 | CHEMBL4040 |
| Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
| Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HCAR2 | Hydroxycarboxylic acid receptor 2 | Q8TDS4 | CHEMBL3785 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2B | Alpha-2b adrenergic receptor | P18089 | CHEMBL1942 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR4 | G-protein coupled receptor 120 | Q5NUL3 | CHEMBL5339 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR1 | Free fatty acid receptor 1 | O14842 | CHEMBL4422 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM8 | Metabotropic glutamate receptor 8 | O00222 | CHEMBL3228 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM1 | Metabotropic glutamate receptor 1 | Q13255 | CHEMBL3772 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transcription factor | AHR | Aryl hydrocarbon receptor | P35869 | CHEMBL3201 |
| Therapeutic Target | Transcription factor | HIF1A | Hypoxia-inducible factor 1 alpha | Q16665 | CHEMBL4261 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
| Therapeutic Target | Transferase | GSTP1 | Glutathione S-transferase Pi | P09211 | CHEMBL3902 |
| Therapeutic Target | Unclassified protein | SNCA | Alpha-synuclein | P37840 | CHEMBL6152 |
Clinical Trials Summary
Overview
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 564 | |
Clinical trial details
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT00396500 | Deworming and Vitamin A (DEVTA) Prepilot Study | malnutrition;parasitic infection | Retinol (NPC55412) | NP level |
| NCT04631536 | Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC | COVID-19 | Arginine (NPC226453);Folic Acid (NPC147983) | NP level |
| NCT00271635 | Ascorbic Acid Treatment in CMT1A Trial (AATIC) | Charcot-Marie-Tooth disease | Ascorbate (NPC187770) | NP level |
| NCT02061449 | Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma | Cutaneous T-cell lymphoma | Lysine (NPC112890) | NP level |
| NCT02521077 | Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT01587261 | Vitamin C for Severe Thermal Injuries | injury | Ascorbate (NPC187770) | NP level |
| NCT02220244 | Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT02908581 | Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis | heavy metal poisoning | Folic Acid (NPC147983) | NP level |
| NCT00508989 | Niacin to Improve Blood Flow in People With Sickle Cell Disease | sickle cell anemia | Niacin (NPC167400) | NP level |
| NCT04476277 | Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease | sickle cell anemia | Biotin (NPC199072) | NP level |
| NCT03266965 | Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT03680274 | Lessening Organ Dysfunction With VITamin C | COVID-19;Sepsis | Ascorbate (NPC187770) | NP level |
| NCT00480207 | Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults | depressive disorder | Folic Acid (NPC147983) | NP level |
| NCT00703196 | Folic Acid Clinical Trial for the Prevention of Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT00300365 | Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL | metabolic syndrome | Niacin (NPC167400) | NP level |
| NCT00661544 | Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02447874 | Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02730949 | D-chiro-Inositol in Overweight Type 1 Diabetes Patients | type 1 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT02655913 | Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01287585 | Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy | hepatocellular carcinoma | Arginine (NPC226453) | NP level |
| NCT03745963 | The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU | pain | Sucrose (NPC130683) | NP level |
| NCT01873443 | Long-Term Efficacy and Safety of CT-P10 in Patients With RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02293902 | A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03418038 | Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or Clonal Cytopenia of Undetermined Significance | Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Thiamine (NPC150950) | NP level |
| NCT02612259 | A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity | obesity | Tryptophan (NPC203468) | NP level |
| NCT00067899 | Oxidative Stress and Vitamin E Requirements | nicotine dependence | Ascorbate (NPC187770) | NP level |
| NCT02390505 | Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery | complex regional pain syndrome | Ascorbate (NPC187770) | NP level |
| NCT04703361 | Effects of Ketones and Niacin in Heart Failure Patients | systolic heart failure | Niacin (NPC167400) | NP level |
| NCT00446147 | Study of Pyridoxine for Hand-Foot Syndrome | Hand-foot syndrome | Pyridoxine (NPC269919) | NP level |
| NCT03828929 | Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Tryptophan (NPC203468);Histidine (NPC237812) | NP level |
| NCT04750902 | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children | dental caries | Arginine (NPC226453) | NP level |
| NCT00957359 | Psilocybin Cancer Anxiety Study | cancer | Niacin (NPC167400) | NP level |
| NCT00573313 | Effects of SAMe in Patients With Alcoholic Liver Disease | liver disease | Methionine (NPC152451) | NP level |
| NCT02013362 | Phase I/II Clinical Study of Pralatrexate in Japanese Patients With Relapsed or Refractory Peripheral T-cell Lymphoma | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT03224572 | The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00378833 | Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00855257 | Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome | acute coronary syndrome | Niacin (NPC167400) | NP level |
| NCT04035096 | The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients | malignant colon neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00734695 | Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment. | burn | Ascorbate (NPC187770) | NP level |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT00029679 | Borage Oil and Ginkgo Biloba (EGb 761) in Asthma | asthma | Linoleic Acid (NPC85813) | NP level |
| NCT04268849 | Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT04630964 | The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT00000461 | Harvard Atherosclerosis Reversibility Project (HARP) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00301587 | A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT01436266 | Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion | hemorrhage | Folic Acid (NPC147983) | NP level |
| NCT00694564 | Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children | Abdominal pain | Methionine (NPC152451) | NP level |
| NCT03451266 | Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
| NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02868151 | Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers | oral mucositis | Ascorbate (NPC187770) | NP level |
| NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
| NCT00024310 | Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors | neoplasm | Folic Acid (NPC147983) | NP level |
| NCT05501548 | Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer | prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT03516903 | Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI | myocardial infarction | Folic Acid (NPC147983) | NP level |
| NCT00033722 | Lometrexol Plus Folic Acid in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT02903355 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT01852890 | Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00817336 | Biomarkers in Schizophrenia | schizoaffective disorder;schizophrenia | Serine (NPC219143) | NP level |
| NCT05283954 | Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00998946 | Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma | lymphoma | Folic Acid (NPC147983) | NP level |
| NCT00289900 | Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01985685 | The Effect of Thiamine vs. Placebo on VO2 in Critical Illness | respiratory failure | Thiamine (NPC150950) | NP level |
| NCT01920191 | Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma | neoplasm | Lysine (NPC112890) | NP level |
| NCT00150722 | High-Density Lipoprotein (HDL) Modulation and Endothelial Function | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT00133562 | HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT03882177 | StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis | pulmonary tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT02220933 | Effect of MD1003 in Spinal Progressive Multiple Sclerosis | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT03015675 | IV Ascorbic Acid in Advanced Gastric Cancer | gastric cancer | Ascorbate (NPC187770) | NP level |
| NCT00917826 | Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | lymphoma | Arginine (NPC226453) | NP level |
| NCT00638196 | Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS | multiple sclerosis | Oleic Acid (NPC261831) | NP level |
| NCT01364805 | New Treatment Option for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02833701 | Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT00571766 | Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT00903617 | Study to Test GSK256073 in Patients With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01057615 | Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma | asthma | Ascorbate (NPC187770) | NP level |
| NCT03334409 | Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery | clear cell renal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03148236 | Vitamin C in Atrial Fibrillation Ablation | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT05025488 | Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm | essential thrombocythemia;myelofibrosis | Lysine (NPC112890) | NP level |
| NCT00329498 | L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes | acute myeloid leukemia;myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT00262730 | Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT00908791 | Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue | breast cancer | Linoleic Acid (NPC85813) | NP level |
| NCT03101579 | Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT00500045 | Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT04354428 | Treatment for COVID-19 in High-Risk Adult Outpatients | COVID-19 | Ascorbate (NPC187770);Folic Acid (NPC147983) | NP level |
| NCT02586285 | Effect of S-Adenosyl Methionine Treatment on Recurrence After Curative Resection of Hepatocellular Carcinoma | hepatocellular carcinoma | Methionine (NPC152451) | NP level |
| NCT04921189 | Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors | cardiac arrest | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT04046094 | Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients | urinary bladder cancer | Ascorbate (NPC187770) | NP level |
| NCT01715597 | Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma | uterine fibroid | Ascorbate (NPC187770) | NP level |
| NCT00965653 | A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01221402 | Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT04279535 | Topical Vitamin C for Treatment of Basal Cell Cancer | basal cell carcinoma | Ascorbate (NPC187770) | NP level |
| NCT04344184 | SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI) | acute lung injury;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02631668 | the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT00128557 | Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh | vitamin A deficiency | Retinol (NPC55412) | NP level |
| NCT00484510 | High Dose Ascorbic Acid Treatment of CMT1A | Charcot-Marie-Tooth disease type 1A | Ascorbate (NPC187770) | NP level |
| NCT03162562 | The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer | ovarian carcinoma | Lysine (NPC112890) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT02125786 | A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma | ependymoma | Methionine (NPC152451) | NP level |
| NCT03493178 | Glutathione in Mild Cognitive Impairment | Cognitive impairment | Glycine (NPC126681) | NP level |
| NCT00616304 | Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT00000512 | Familial Atherosclerosis Treatment Study | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT02735707 | Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia | COVID-19;influenza;pneumonia | Ascorbate (NPC187770) | NP level |
| NCT05210504 | Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3 | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT02990364 | Combination Analgesia for Neonatal Circumcision | pain | Sucrose (NPC130683) | NP level |
| NCT01850680 | Single Ascending Dose Study of Safety and Tolerability of Sarilumab and Methotrexate in Japanese Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02083575 | Role of Vitamin C to Augment Iron Chelation With DFP or DFX | beta-thalassemia major | Ascorbate (NPC187770) | NP level |
| NCT01324115 | NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors | neoplasm | Arginine (NPC226453) | NP level |
| NCT02541045 | Clinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepatitis | non-alcoholic fatty liver disease | Pyridoxine (NPC269919) | NP level |
| NCT02786823 | Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT02063802 | Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT02427581 | Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy | triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Arginine (NPC226453) | NP level |
| NCT01908452 | Pyridoxal Kinase Activity in Tardive Dyskinesia | movement disorder | Pyridoxine (NPC269919) | NP level |
| NCT04677049 | Study of Niacin in Glioblastoma | glioblastoma multiforme | Niacin (NPC167400) | NP level |
| NCT02018965 | Niacin on Immune Activation : a Proof-of-concept Study | HIV infection | Niacin (NPC167400) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | Sepsis;septic shock | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT03028467 | Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00114400 | BVAIT: B-Vitamin Atherosclerosis Intervention Trial | atherosclerosis | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT03410030 | Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT02516670 | Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer | metastatic prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT00271817 | To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00268749 | Glycine Treatment of Prodromal Symptoms | schizophrenia | Glycine (NPC126681) | NP level |
| NCT03509350 | Vitamin C, Thiamine, and Steroids in Sepsis | Sepsis | Thiamine (NPC150950);Ascorbate (NPC187770) | NP level |
| NCT00634998 | Vitamin C Supplementation as a Preventive Treatment of Diabetic Peripheral Neuropathy | diabetic neuropathy | Ascorbate (NPC187770) | NP level |
| NCT00807807 | Evaluating the Effects of Folic Acid Supplementation in Older Adults: The Folic Acid Supplementation Trial (The FAST Study) | heart disease | Folic Acid (NPC147983) | NP level |
| NCT03427086 | Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis | amyotrophic lateral sclerosis | Biotin (NPC199072) | NP level |
| NCT02929888 | Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients | acute myocardial infarction | Lysine (NPC112890) | NP level |
| NCT00728910 | Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02420314 | Pharmacological Ascorbate for Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02467504 | Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03272594 | The Influence of Breastfeeding on Cortical Activity During Procedures | pain | Sucrose (NPC130683) | NP level |
| NCT00111891 | An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01050621 | Trial of Chemotherapy Plus Intravenous Vitamin C in Patients With Advanced Cancer for Whom Chemotherapy Alone is Only Marginally Effective | cancer | Ascorbate (NPC187770) | NP level |
| NCT02890992 | An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00005658 | Glycine to Treat Psychotic Disorders in Children | schizophrenia | Glycine (NPC126681) | NP level |
| NCT00949104 | Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates | pain | Sucrose (NPC130683) | NP level |
| NCT02129075 | A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma | cutaneous melanoma | Lysine (NPC112890) | NP level |
| NCT01217814 | Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00408577 | Prevention of Cardiac and Vascular Events in Patients With NGT/IGT. | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT01439555 | Endothelial Facilitation in Alzheimer's Disease | Alzheimer disease | Arginine (NPC226453) | NP level |
| NCT02369822 | Trial of Vitamin C as Add on Therapy for Children With Idiopathic Epilepsy | epilepsy | Ascorbate (NPC187770) | NP level |
| NCT00065455 | Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT04928495 | Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00054938 | Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE) | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT01752491 | A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT00611000 | Effect of Folate on DNA in Colon Tissue and Blood Samples From Patients at Increased Risk of Developing Colorectal Neoplasia | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01031927 | N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD) | obsessive-compulsive disorder | Glycine (NPC126681) | NP level |
| NCT04201873 | Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT01201954 | Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning | pain | Sucrose (NPC130683) | NP level |
| NCT04335084 | A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT04952051 | Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension | hypertension | Folic Acid (NPC147983) | NP level |
| NCT00803530 | Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes | myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT00222235 | Adjunctive Treatment for Decreasing Symptoms of Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT04516681 | IV Ascorbic Acid in Peritoneal Metastatic Colorectal Cancer | colorectal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00405665 | The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis | cystic fibrosis | Arginine (NPC226453) | NP level |
| NCT03580616 | Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS) | amyotrophic lateral sclerosis | Serine (NPC219143) | NP level |
| NCT01165021 | A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00204932 | Effects of CLA Supplements on Body Weight and Fat Oxidation | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT02702492 | PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA) | non-Hodgkins lymphoma | Niacin (NPC167400) | NP level |
| NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT02379091 | Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01796678 | Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial | pain | Arginine (NPC226453) | NP level |
| NCT02109614 | Early Aortic Valve Lipoprotein(a) Lowering Trial | aortic stenosis | Niacin (NPC167400) | NP level |
| NCT00345605 | Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder | argininosuccinic aciduria | Arginine (NPC226453) | NP level |
| NCT04345705 | Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma | mesothelioma | Lysine (NPC112890) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Folic Acid (NPC147983);Pyridoxine (NPC269919);Beta Carotene (NPC17810) | NP level |
| NCT02947750 | Neurovascular Transduction During Exercise in Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Quercetin (NPC20791) | NP level |
| NCT01733407 | L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 | hereditary sensory and autonomic neuropathy type 1 | Serine (NPC219143) | NP level |
| NCT04357782 | Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation | hypoxia;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01188096 | A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT03082001 | Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies | pain | Sucrose (NPC130683) | NP level |
| NCT04553666 | Reducing Frailty for Older Cancer Survivors Using Supplements | inflammation | Ascorbate (NPC187770) | NP level |
| NCT00961636 | A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983);Ascorbate (NPC187770) | NP level |
| NCT01054508 | Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00664287 | Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02930343 | Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00034463 | ALIMTA (Pemetrexed) in Patients With Locally Advanced or Metastatic Cancer | cancer | Folic Acid (NPC147983) | NP level |
| NCT03752918 | The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. | post-traumatic stress disorder | Niacin (NPC167400) | NP level |
| NCT00227682 | Arsenic Trioxide, Thalidomide, Dexamethasone, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00491569 | Sarcosine or D-Serine Add-on Treatment for Chronic Schizophrenia | schizophrenia | Serine (NPC219143) | NP level |
| NCT02107976 | Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT02225886 | Ascorbic Acid Administration in the Treatment of Anemia in Chronic Hemodialysed Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT00120289 | Niacin Plus Statin to Prevent Vascular Events | stroke;atherosclerosis;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT00317811 | Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03685773 | The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01388764 | Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT02017249 | Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme | glioblastoma multiforme | Arginine (NPC226453) | NP level |
| NCT00080275 | Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00108589 | S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis | Hepatitis | Methionine (NPC152451) | NP level |
| NCT01243242 | Clinical Efficacy & Safety, of Metadoxine (MG01CI) Extended Release in Attention-Deficit Hyperactivity Disorder (ADHD) | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT01116141 | A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT05042024 | Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | periodontitis | Arginine (NPC226453) | NP level |
| NCT03861416 | "Unifuzol®" in Patients With Peripheral Arterial Disease | peripheral arterial disease | Arginine (NPC226453) | NP level |
| NCT01407432 | Impact of Folates in the Care of the Male Infertility | male infertility | Folic Acid (NPC147983) | NP level |
| NCT02318446 | Efficacy Study of Folic Acid Supplementation in Adolescent Epileptics | epilepsy | Folic Acid (NPC147983) | NP level |
| NCT00995085 | Efficacy Study of Metadoxine SR Formulation in Attention Deficit Hyperactivity Disorder (ADHD) Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT03887169 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | pulmonary alveolar proteinosis | Methionine (NPC152451);Folic Acid (NPC147983);Ascorbate (NPC187770);Pyridoxine (NPC269919) | NP level |
| NCT00954525 | Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02066688 | Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT00085345 | Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01983969 | Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma | cancer;lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00652431 | Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00441870 | Study of EC0225 for the Treatment of Refractory or Metastatic Tumors | cancer | Folic Acid (NPC147983) | NP level |
| NCT01107730 | Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT00607945 | Dietary Fatty Acids as Complementary Therapy in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Linoleic Acid (NPC85813) | NP level |
| NCT03602235 | High Dose Ascorbic Acid for Plasma Cell Disorders | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02393378 | Namilumab vs Adalimumab in Participants With Moderate to Severe Early Rheumatoid Arthritis Inadequately Responding to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01104519 | A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01070810 | Thiamine as a Metabolic Resuscitator in Septic Shock | septic shock | Thiamine (NPC150950) | NP level |
| NCT02541708 | IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in Tanzania | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT05470998 | L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00269204 | Lipid Efficacy/Tolerability Study (0524A-020) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00062556 | Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT03268733 | The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome | polycystic ovary syndrome | Folic Acid (NPC147983) | NP level |
| NCT00137124 | L-Arginine Metabolism in Essential Hypertension | essential hypertension | Arginine (NPC226453) | NP level |
| NCT00120822 | Folic Acid Supplementation in Gambian Primigravidae | malaria | Folic Acid (NPC147983) | NP level |
| NCT00056225 | VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study) | Alzheimer disease | Pyridoxine (NPC269919);Folic Acid (NPC147983) | NP level |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer | rectum cancer | Ascorbate (NPC187770) | NP level |
| NCT00470522 | Study of Methotrexate in Lupus Erythematosus | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT00298272 | Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02075970 | Optimized Erythropoietin (EPO) Treatment | neonatal anemia | Biotin (NPC199072) | NP level |
| NCT00441207 | Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors | cancer | Ascorbate (NPC187770) | NP level |
| NCT01042535 | Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer | male breast carcinoma | Tryptophan (NPC203468) | NP level |
| NCT00300352 | Effect of Folic Acid Treatment in Coronary Artery Disease | coronary artery disease | Folic Acid (NPC147983) | NP level |
| NCT03606967 | Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT05378919 | Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer | rectum cancer | Folic Acid (NPC147983) | NP level |
| NCT03718507 | Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants | acute respiratory distress syndrome | Sucrose (NPC130683) | NP level |
| NCT04989049 | Therapeutic Effect of Folic Acid in Healing of Oral Ulcers | Oral ulcer | Folic Acid (NPC147983) | NP level |
| NCT00618995 | A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT02388178 | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study | dental caries | Arginine (NPC226453) | NP level |
| NCT01550510 | Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | colorectal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT00000324 | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 | cocaine dependence | Tryptophan (NPC203468) | NP level |
| NCT01555489 | Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03581773 | Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy | mucositis | Folic Acid (NPC147983) | NP level |
| NCT00406874 | Effect of Omega 3 Fats on Sperm Quality and Sexual Function | infertility | Folic Acid (NPC147983) | NP level |
| NCT00626444 | Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL) | non-Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Arginine (NPC226453) | NP level |
| NCT02563327 | Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT00157521 | L-Arginine in Pre-Eclampsia | preeclampsia | Arginine (NPC226453) | NP level |
| NCT00402883 | Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction | Folic Acid (NPC147983);Beta Carotene (NPC17810);Ascorbate (NPC187770);Pyridoxine (NPC269919) | NP level |
| NCT00112879 | Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03437902 | Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT02344355 | A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT03799094 | Vitamin C and Tyrosine Kinase Inhibitor in Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
| NCT00533312 | MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02678234 | An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT01842139 | Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission | acute myeloid leukemia | Lysine (NPC112890) | NP level |
| NCT00633581 | Efficacy of Vitamin C Injection on Fatigue in Workers After Work | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT01014546 | Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis | essential thrombocythemia;polycythemia vera;primary myelofibrosis | Ascorbate (NPC187770) | NP level |
| NCT00056433 | Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00345150 | Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls | hypertension | Arginine (NPC226453) | NP level |
| NCT00567931 | 1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT00223717 | Treatment of Supine Hypertension in Autonomic Failure | hypertension | Arginine (NPC226453) | NP level |
| NCT01835782 | Determining the Safety of L-serine in ALS | amyotrophic lateral sclerosis | Serine (NPC219143) | NP level |
| NCT03649633 | Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT01238471 | Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study | retinopathy of prematurity | Sucrose (NPC130683) | NP level |
| NCT01661764 | Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention | colorectal adenoma | Oleic Acid (NPC261831) | NP level |
| NCT02109315 | Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes. | type 1 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT01711359 | A Study in Participants With Moderate to Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00280683 | Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma | asthma | Arginine (NPC226453) | NP level |
| NCT00202280 | Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication | psychosis | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT01183065 | Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) | head and neck malignant neoplasia | Folic Acid (NPC147983) | NP level |
| NCT04363216 | Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00672360 | Folate Rechallenge | autism | Folic Acid (NPC147983) | NP level |
| NCT03446456 | Vasopressin and Pain Perception in the Brain | pain | Arginine (NPC226453) | NP level |
| NCT00325572 | Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism | autism | Ascorbate (NPC187770) | NP level |
| NCT01783431 | Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells | melanoma | Lysine (NPC112890) | NP level |
| NCT00215878 | D-serine for Posttraumatic Stress Disorder Treatment | post-traumatic stress disorder | Serine (NPC219143) | NP level |
| NCT00004758 | Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment | epilepsy | Pyridoxine (NPC269919) | NP level |
| NCT00806819 | Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT05281926 | A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients | hepatocellular carcinoma | Lysine (NPC112890) | NP level |
| NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
| NCT00485758 | Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Ascorbate (NPC187770);Pyridoxine (NPC269919);Niacin (NPC167400);Folic Acid (NPC147983);Retinol (NPC55412);Biotin (NPC199072) | NP level |
| NCT00578305 | A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00000553 | HDL-Atherosclerosis Treatment Study (HATS) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00769132 | A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01419067 | A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection | Craniopharyngioma | Methionine (NPC152451) | NP level |
| NCT00943124 | MK0524B Bioequivalence Study (0524B-070) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT03090048 | Vitamin A and Azithromycin for Acne Vulgaris | acne | Retinol (NPC55412) | NP level |
| NCT00006136 | Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | Beta-thalassemia | Arginine (NPC226453) | NP level |
| NCT00203476 | A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00269217 | Lipid Efficacy Study (0524B-022)(COMPLETED) | Combined hyperlipidemia;Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00284427 | Safety of Antioxidants During GYN Cancer Care | cervical cancer;ovarian cancer | Ascorbate (NPC187770) | NP level |
| NCT00536510 | Effect of MK0524A on Cholesterol Levels (0524A-048) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT03800667 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT02699099 | Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. | malaria | Retinol (NPC55412) | NP level |
| NCT00071266 | The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT03062449 | Phase IIa L-serine Trial for eAD | Alzheimer disease | Serine (NPC219143) | NP level |
| NCT04703036 | Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19 | COVID-19 | Glycine (NPC126681) | NP level |
| NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
| NCT01080352 | Vitamin C as an Anti-cancer Drug | prostate adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT03175341 | Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer | breast cancer | Ascorbate (NPC187770) | NP level |
| NCT01720095 | Niapsan as Add -on Therapy to Antipsychotic Treatment in First Episode Psychosis | psychosis | Niacin (NPC167400) | NP level |
| NCT00953134 | Periconceptional Iron Supplementation in Rural Bangladesh | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT02730364 | An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT01561547 | Trial of Repeated Analgesia With Kangaroo Care | pain | Sucrose (NPC130683) | NP level |
| NCT04347889 | Preventing COVID-19 in Healthcare Workers With HCQ: A RCT | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01426438 | Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate | HIV-1 infection | Niacin (NPC167400) | NP level |
| NCT02189772 | Safety and Tolerability Study of Metadoxine Extended Release (MDX) (Previously Known as MG01CI) in PI-ADHD Adolescent Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT01502280 | Fluorescence-guided Surgery for Low- and High-grade Gliomas | glioma | Ascorbate (NPC187770) | NP level |
| NCT01368328 | Effect of the Chromium Nicotinate on Type 2 Diabetes | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01057589 | A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer | upper aerodigestive tract neoplasm | Folic Acid (NPC147983) | NP level |
| NCT04337879 | A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | colorectal cancer | Folic Acid (NPC147983) | NP level |
| NCT01587963 | High Dose Vitamin C in the Critically Ill Patient | Shock | Ascorbate (NPC187770) | NP level |
| NCT00554827 | Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | Cutaneous T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT00513617 | Effectiveness of Arginine as a Treatment for Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT03188445 | Intravenous Iron Isomaltoside Versus Oral Iron Supplementation for Treatment of Iron Deficiency in Pregnancy. | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT01083329 | Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects | obesity | Niacin (NPC167400) | NP level |
| NCT02067975 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | schizophrenia | Tryptophan (NPC203468) | NP level |
| NCT00631111 | Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain | pain | Ascorbate (NPC187770) | NP level |
| NCT04446104 | A Preventive Treatment for Migrant Workers at High-risk of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01503060 | Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain | pain | Sucrose (NPC130683) | NP level |
| NCT05284656 | Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT04478734 | Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease | Huntington disease | Thiamine (NPC150950);Biotin (NPC199072) | NP level |
| NCT00609518 | A Study for Patients With Non-Squamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01720316 | Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders | bipolar disorder | Glycine (NPC126681) | NP level |
| NCT03510884 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Ascorbate (NPC187770) | NP level |
| NCT00452829 | Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study) | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT01936831 | High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB) | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT01295450 | Study to Evaluate the Efficacy and Tolerability of Apevinat BC Compared to Vitamin Complex | Anorexia | Ascorbate (NPC187770) | NP level |
| NCT03450707 | Thiamine as a Metabolic Resuscitator After Cardiac Arrest | cardiac arrest | Thiamine (NPC150950) | NP level |
| NCT02093026 | Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02795299 | Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02756117 | The Effect of Acute Lysine Administration on α-aminoadipic Acid | prediabetes syndrome | Lysine (NPC112890) | NP level |
| NCT00973609 | Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC) | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT00533611 | Effect of MK0524A on Flushing Caused by Niacin (0524A-056) | Flushing | Niacin (NPC167400) | NP level |
| NCT01266018 | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Arginine (NPC226453) | NP level |
| NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Methionine (NPC152451) | NP level |
| NCT04370288 | Clinical Application of Methylene Blue for Treatment of Covid-19 Patients | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00006021 | Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT04482686 | Trial of Combination Therapy to Treat COVID-19 Infection | COVID-19;severe acute respiratory syndrome | Ascorbate (NPC187770) | NP level |
| NCT02762838 | Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02168270 | Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma | anaplastic astrocytoma;anaplastic oligodendroglioma;gliosarcoma | Ascorbate (NPC187770) | NP level |
| NCT00070434 | S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT02734147 | High Dose Intravenous Ascorbic Acid in Severe Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT01115504 | Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy | heart failure | Thiamine (NPC150950) | NP level |
| NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT04900792 | A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT01580683 | Vitamin C and Atrial Fibrillation After Cardiac Surgery | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT03697239 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT03359239 | Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer | urinary bladder cancer | Lysine (NPC112890) | NP level |
| NCT03088345 | Early Use of Vasopressin in Post-Fontan Management | congenital heart disease | Arginine (NPC226453) | NP level |
| NCT00000599 | Cholesterol-Lowering Atherosclerosis Study (CLAS) | carotid artery disease;cerebral atherosclerosis;Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT04404387 | Lessening Organ Dysfunction With VITamin C in Septic ARDS | acute respiratory distress syndrome | Ascorbate (NPC187770) | NP level |
| NCT02174705 | Rotavirus vs. Sucrose for Vaccine Injection Pain | pain | Sucrose (NPC130683) | NP level |
| NCT00152893 | To Determine if Chromium Nicotinate Supplementation Will Improve Insulin Resistance in HIV Patients With Metabolic Abnormalities | HIV infection | Niacin (NPC167400) | NP level |
| NCT00047983 | Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant Patients | kidney disease | Arginine (NPC226453) | NP level |
| NCT04261036 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT01061736 | Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00000600 | Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up | carotid artery disease;cerebral atherosclerosis;heart disease | Ascorbate (NPC187770) | NP level |
| NCT01984073 | Effects of Niacin On Fatty Acid Trapping | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00344734 | Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure | congestive heart failure | Arginine (NPC226453) | NP level |
| NCT00096330 | Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Thiamine (NPC150950) | NP level |
| NCT00299130 | A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01703104 | The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT05096663 | Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01118624 | Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer | breast carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00127218 | High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT00000555 | Women's Angiographic Vitamin and Estrogen Trial (WAVE) | menopause;Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT00986609 | MUC1 Vaccine for Triple-negative Breast Cancer | inflammatory breast carcinoma;triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT01685281 | Study Comparing Two Doses of MG01CI and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00677339 | L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) | pulmonary tuberculosis | Arginine (NPC226453) | NP level |
| NCT03166254 | Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer | non-small cell lung carcinoma | Lysine (NPC112890) | NP level |
| NCT00536237 | MK0524A Phase IIb Study (0524A-011)(COMPLETED) | Flushing | Niacin (NPC167400) | NP level |
| NCT03964688 | Effect of Vitamin C in Autologous Stem Cell Transplantations | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03541486 | A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT03592693 | Vitamin C, Hydrocortisone and Thiamine for Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT00338221 | Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT00520247 | Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism | hypertension | Folic Acid (NPC147983) | NP level |
| NCT02936037 | Effect of MD1003 in Progressive Multiple Sclerosis (SPI2) | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT01569919 | A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma | mesothelioma | Folic Acid (NPC147983) | NP level |
| NCT00266227 | A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00276263 | Sarcosine Preventive Therapy for Individuals At High Risk for Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT04616248 | In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT00134433 | Endothelial Modulation for Angiogenic Therapy | coronary artery disease | Arginine (NPC226453) | NP level |
| NCT01603446 | L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome | MELAS | Arginine (NPC226453) | NP level |
| NCT03540758 | Regulation of Endogenous Glucose Production by Central KATP Channels | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT03580122 | The Effect of Arginine on Classic Galactosemia | classic galactosemia | Arginine (NPC226453) | NP level |
| NCT00397657 | Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT04401150 | Lessening Organ Dysfunction With VITamin C - COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00243412 | A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04740580 | Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease | Alzheimer disease | Glycine (NPC126681) | NP level |
| NCT02424201 | Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja. | postpartum hemorrhage | Ascorbate (NPC187770) | NP level |
| NCT00291226 | Glycine vs Placebo for the Schizophrenia Prodrome | schizophrenia | Glycine (NPC126681) | NP level |
| NCT02780505 | Assessment of the Effect of Vitamin C on Anemia in Patients With Continuous Ambulatory Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT04054973 | L-arginine Study for Persistent Symptoms of Schizophrenia | schizophrenia | Arginine (NPC226453) | NP level |
| NCT03624270 | Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia | acute promyelocytic leukemia | Ascorbate (NPC187770) | NP level |
| NCT00299104 | A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03068832 | Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT00258245 | Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00200746 | Treatment of Alcohol-Related Hepatitis With Arginine | Hepatitis, Alcoholic | Arginine (NPC226453) | NP level |
| NCT01828437 | Addition of Pyridoxine to Prednisolone in Infantile Spasms | West syndrome | Pyridoxine (NPC269919) | NP level |
| NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
| NCT04535427 | Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Arginine (NPC226453) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Ascorbate (NPC187770) | NP level |
| NCT00953212 | Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery | atrial fibrillation;atrial flutter | Ascorbate (NPC187770) | NP level |
| NCT02961816 | Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00000372 | Glycine and D-Cycloserine in Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT04395768 | International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00143702 | D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE) | lactic acidosis | Thiamine (NPC150950) | NP level |
| NCT02291458 | L-arginine and Brown Adipose Tissue | Glucose intolerance | Arginine (NPC226453) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT01670955 | The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT01949116 | Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications | HIV infection | Folic Acid (NPC147983) | NP level |
| NCT03066115 | Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation | hypoxia | Ascorbate (NPC187770) | NP level |
| NCT05289908 | Intrathecal Pemetrexed for Leptomeningeal Metastasis | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT01900431 | Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis | uveitis | Folic Acid (NPC147983) | NP level |
| NCT00920413 | Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT03797443 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00154700 | Twice Weekly TP-HDFL for Recurrent or Metastatic Esophageal Cancer | esophageal cancer | Folic Acid (NPC147983) | NP level |
| NCT04249336 | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH | allergic disease | Arginine (NPC226453) | NP level |
| NCT00000482 | Coronary Drug Project | Myocardial Ischemia;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT00951158 | A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors | neoplasm | Linoleic Acid (NPC85813) | NP level |
| NCT03956056 | Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy | pancreatic carcinoma | Lysine (NPC112890) | NP level |
| NCT00469209 | Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01319734 | Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00787059 | AC6 Gene Transfer for CHF | congestive heart failure | Sucrose (NPC130683) | NP level |
| NCT00606502 | Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT03223519 | COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS) | muscular disease | Ascorbate (NPC187770) | NP level |
| NCT01417481 | Effect of Glycine in Cystic Fibrosis | cystic fibrosis | Glycine (NPC126681) | NP level |
| NCT01010581 | SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04783792 | The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention | osteoarthritis | Ascorbate (NPC187770) | NP level |
| NCT00630877 | Evaluation of a Flushing ASsessment Tool (FAST) in Subjects Receiving Niacin Extended-release Plus Aspirin | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02086864 | A Placebo Controlled Study of Homeopathic Treatment of Children and Youth With ADHD | attention deficit hyperactivity disorder | Sucrose (NPC130683) | NP level |
| NCT00098319 | Oral Cleft Prevention Trial in Brazil | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT05363917 | Natrunix Versus Methotrexate in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03509662 | Vitamin C in Post-cardiac Arrest | cardiac arrest | Thiamine (NPC150950);Ascorbate (NPC187770) | NP level |
| NCT00220532 | Folate and Protection Against Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT02186158 | Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized. | pneumonia | Ascorbate (NPC187770) | NP level |
| NCT03866174 | A Study of Psilocybin for Major Depressive Disorder (MDD) | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT00397917 | Oral Cleft Prevention Program | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT02114502 | Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma | multiple myeloma | Pyridoxine (NPC269919) | NP level |
| NCT00804843 | Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED) | carotid atherosclerosis | Niacin (NPC167400) | NP level |
| NCT03121677 | Personalized Tumor Vaccine Strategy and PD-1 Blockade in Patients With Follicular Lymphoma | follicular lymphoma | Lysine (NPC112890) | NP level |
| NCT03356483 | Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study. | obsessive-compulsive disorder | Niacin (NPC167400) | NP level |
| NCT01194453 | Pemetrexed Plus Cisplatin Versus Gemcitabine Plus Cisplatin for Advanced NSCLC Metastatic Non-small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01976676 | Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion | habitual abortion | Folic Acid (NPC147983) | NP level |
| NCT01071291 | Effects of Niaspan™ on High-density Lipoprotein (HDL) in Healthy Male Subjects (0000-069) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
| NCT05009355 | The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00781196 | Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth | gingival overgrowth | Folic Acid (NPC147983) | NP level |
| NCT02833350 | Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00388856 | Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT01345474 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT00384293 | Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00731588 | Red Blood Cell (RBC) Survival Following Transfusion in Infants | neonatal anemia | Biotin (NPC199072) | NP level |
| NCT00052715 | Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT02589145 | Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00000116 | Randomized Trial of DHA for Retinitis Pigmentosa Patients Receiving Vitamin A | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT02701673 | Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT01188876 | Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer | fallopian tube cancer;ovarian cancer;peritoneum cancer | Folic Acid (NPC147983) | NP level |
| NCT00211562 | Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids | schizophrenia | Ascorbate (NPC187770) | NP level |
| NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
| NCT00170404 | TB Nutrition, Immunology and Epidemiology | tuberculosis | Niacin (NPC167400);Folic Acid (NPC147983);Retinol (NPC55412) | NP level |
| NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Quercetin (NPC20791) | NP level |
| NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT00974714 | L-arginine Effects on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT00575848 | Study of the Effects of Glycine on Symptoms and Memory in Patients With Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT03522922 | Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring | acne | Ascorbate (NPC187770) | NP level |
| NCT01785186 | Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT01953536 | Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004) | breast neoplasm | Folic Acid (NPC147983) | NP level |
| NCT02757898 | Transfusion of Biotinylated Red Blood Cells | anemia (phenotype) | Biotin (NPC199072) | NP level |
| NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
| NCT02793648 | Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly. | depressive disorder | Ascorbate (NPC187770) | NP level |
| NCT00272610 | Topical Vitamin A Versus Vehicle Cream in the Treatment of Aged Skin | Purpura | Retinol (NPC55412) | NP level |
| NCT00058123 | Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT00499265 | Gemcitabine With or Without WX-671 in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery | pancreatic carcinoma | Serine (NPC219143) | NP level |
| NCT04334512 | A Study of Quintuple Therapy to Treat COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00519207 | Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture | pain | Sucrose (NPC130683) | NP level |
| NCT03508726 | High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas | soft tissue sarcoma | Ascorbate (NPC187770) | NP level |
| NCT00082251 | Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02602483 | Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). | temporomandibular joint disorder | Ascorbate (NPC187770) | NP level |
| NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT03872011 | Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock | septic shock | Thiamine (NPC150950);Ascorbate (NPC187770) | NP level |
| NCT00136188 | Nitric Oxide (NO) Activity and Diabetic Nephropathy | diabetic nephropathy | Folic Acid (NPC147983) | NP level |
| NCT00475176 | S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C | chronic hepatitis C virus infection | Methionine (NPC152451) | NP level |
| NCT04855266 | Iron Sucrose in Patients With Iron Deficiency and POTS | orthostatic hypotension | Sucrose (NPC130683) | NP level |
| NCT01501942 | Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma | asthma | Glycine (NPC126681) | NP level |
| NCT03481790 | Lactoferrin Versus Ferrous Sulphate for Treatment of Iron Deficiency Anaemia During Pregnancy | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT00482560 | Analgesic Effect of Breast Feeding vs Sucrose in Neonatal Screening | pain | Sucrose (NPC130683) | NP level |
| NCT02606773 | "Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT01792310 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | glioma | Oleic Acid (NPC261831) | NP level |
| NCT02969681 | Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer | colorectal neoplasm | Ascorbate (NPC187770) | NP level |
| NCT01468038 | A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food | Sleep Disorder | L-Glutamate (NPC137958) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract;macular degeneration | Ascorbate (NPC187770);Beta Carotene (NPC17810) | NP level |
| NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
| NCT05457959 | Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant | glioma | Lysine (NPC112890) | NP level |
| NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
| NCT00950989 | Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00133406 | Long-term Impact and Intervention for Diarrhea in Brazil | diarrheal disease | Retinol (NPC55412);Glycine (NPC126681) | NP level |
| NCT01191216 | 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT00000114 | Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT03166228 | Hemodynamic Changes During Operative Hysteroscopy | hypertension | Glycine (NPC126681) | NP level |
| NCT01140646 | Evaluation of SAMe for Hot Flashes | Hot flashes | Methionine (NPC152451) | NP level |
| NCT01190995 | Role of Repeated Painful Procedures in Preterm Neonates on Short Term Neurobehavioural Outcome | pain | Sucrose (NPC130683) | NP level |
| NCT02773147 | Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine | HIV infection | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT04764383 | Histaminergic Basis of Fatigue in Multiple Sclerosis | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT01490944 | Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT02516085 | Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT01871766 | Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy | rhabdomyosarcoma | Methionine (NPC152451) | NP level |
| NCT03510715 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03172325 | Study to Demonstrate Non-Inferior Efficacy and Safety of CinnoRA® Versus Humira® for Treatment of Active RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT05452772 | 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder | nicotine dependence | Niacin (NPC167400) | NP level |
| NCT01864057 | Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants | beriberi | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT00493064 | To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT04898023 | Zinc and Green Tea Extract for Community Respiratory Viral Infections | viral disease | Ascorbate (NPC187770) | NP level |
| NCT00763633 | B6 Treatment for Nausea and Vomiting in Pregnancy | Nausea and vomiting | Pyridoxine (NPC269919) | NP level |
| NCT04900415 | Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction | COVID-19 | Retinol (NPC55412) | NP level |
| NCT01356966 | Exercise Intolerance in Renal Failure | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT01142219 | L-Arginine and Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00002650 | High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT02744820 | Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT04301336 | Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT02905591 | A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03908333 | High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT01134341 | Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | anaplastic large cell lymphoma;mycosis fungoides;Sezary's disease | Folic Acid (NPC147983) | NP level |
| NCT01905150 | Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02206425 | Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01071525 | The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT04328961 | Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP) | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT04364750 | Biomarkers of Diet-microbiota Interactions in Irritable Bowel Syndrome | irritable bowel syndrome | Histidine (NPC237812) | NP level |
| NCT00944645 | MK0524A Bioequivalence Study (0524A-059) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02297399 | Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00626392 | Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
| NCT00796887 | Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery | Ischemic stroke | Niacin (NPC167400) | NP level |
| NCT04715022 | Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) | hypertension | Ascorbate (NPC187770) | NP level |
| NCT00147368 | Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT02440061 | Ghrelin and Beta Cell Function in Diabetes | type 2 diabetes mellitus | Arginine (NPC226453) | NP level |
| NCT01321034 | Effect of Niacin in the Lipoprotein (a) Concentration | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00133419 | Micronutrients and Enteric Infections in African Children | infection | Retinol (NPC55412) | NP level |
| NCT00376584 | Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) | Disorder of lipid metabolism;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791) | NP level |
| NCT02106650 | Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT01583647 | A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00005107 | Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT02878265 | The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children | malaria | Retinol (NPC55412) | NP level |
| NCT00861523 | Does Thiamine Help Vomiting and Nausea in Pregnancy? | hyperemesis gravidarum | Thiamine Hydrochloride (NPC189436);Thiamine (NPC150950) | NP level |
| NCT00929370 | A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam. | schizophrenia | Glycine (NPC126681) | NP level |
| NCT01891747 | A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma | malignant glioma | Ascorbate (NPC187770) | NP level |
| NCT02504671 | Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00216099 | Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer | prostate cancer | Folic Acid (NPC147983) | NP level |
| NCT00344916 | Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT03640949 | Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest | sudden cardiac arrest | Arginine (NPC226453) | NP level |
| NCT01590303 | Outcome Following Vitamin C Administration in Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT02791906 | Targeting Central Pulsatile Hemodynamics in Chronic Kidney Disease | chronic kidney disease | Ascorbate (NPC187770) | NP level |
| NCT00218946 | Nasogastric Tube in Premature Babies - Pain and Treatment | premature birth | Sucrose (NPC130683) | NP level |
| NCT03679780 | The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT00184054 | Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous Leukemia | acute myeloid leukemia | Ascorbate (NPC187770) | NP level |
| NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
| NCT00215917 | D-Serine Monotherapy for Schizophrenia | schizophrenia | Serine (NPC219143) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SNCA,SRC,GRM5,GSK3B,GRIA2,GRIA3,GRIA4,GRIN2B,GRIA1
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT00508989,NCT02447874,NCT00056433,NCT04301336,NCT01703104,NCT05470998,NCT00513617,NCT01142219,NCT04476277
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLCO1B1,TYR,GRM8,HCAR2,NOX4,MET,MMP12,NPSR1,CYP1A1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
GRIK1,DPP4,GSTP1,SRC,CA4,FABP3,SNCA,CA2,LMNA
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
HIF1A
NCT04715022,NCT00223717,NCT04952051,NCT00345150,NCT00520247,NCT03166228,NCT04832009 |
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARA
NCT00378833,NCT00536510,NCT01583647,NCT00384293,NCT00203476,NCT00376584,NCT00652431 |
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
EGFR,AHR,GSTP1,KDR,AXL,TP53
NCT00329498,NCT00803530 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
XDH,IGF1R
NCT02947750,NCT02848131,NCT05284656,NCT02791906,NCT01356966,NCT00047983 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
OR51E2,SLCO1B1,FABP5,NOX4,ALOX15,GRIN3A
NCT01080352,NCT01912820 |
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT00262730,NCT02833701,NCT04677049,NCT04900792,NCT01752491,NCT04201873,NCT02017249,NCT02344355
|
AnemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00-3A9Z |
NCT00953134,NCT01670955,NCT02780505,NCT00920413,NCT01490944,NCT02631668,NCT02225886,NCT02757898
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
CYP19A1,DPP4,AXL,GRM1,NFKB1,MET,HCAR2,GRIN3A
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP2C9,SLCO1B1,CYP3A4,CDK1,CYP1A2,AURKB,CA2,AKR1B1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
ALOX5,FLT3,AHR,DPP4,NFKB1
MMP12,FABP5 |
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
SRC,MET,TP53,FLT3,KDR
NCT01188876,NCT00284427 |
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
SRC,MET,HCAR2,PPARA,KDR
NCT00408577,NCT03679780 |
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MET,CSNK2A1,MKNK1,IGF1R,EGFR,MKNK2,KDR
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
GRIA3,GRIN2B,AKR1B1,GRIA1,GRIA2,CYP19A1,GRIA4
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
ALOX5,CA4,MMP12
NCT00280683,NCT01501942,NCT01057615,NCT00029679 |
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT01263041,NCT03680274,NCT03333278,NCT02734147,NCT04999137,NCT03509350,NCT01590303
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT04999137,NCT03333278,NCT03872011,NCT03649633,NCT01070810,NCT03592693,NCT03828929
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT01050621,NCT00441207,NCT00034463,NCT00957359,NCT04733534,NCT01983969,NCT00441870
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT01364805,NCT03956056,NCT00954525,NCT01905150,NCT00499265,NCT01555489,NCT03797443
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000599,NCT00000553,NCT00000461,NCT00000541,NCT00000555,NCT00000482,NCT00000512
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
YES1,FFAR1,SLC1A1,ADRA2B,CYP1A1
NCT00054938,NCT00470522 |
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01920191,NCT00567931,NCT01057589,NCT00024310,NCT00951158,NCT01324115,NCT01191216
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
SLCO1B1,AKR1C3,NOX4,MMP12,NPSR1,AURKB,FABP4
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
SLCO1B1,CDK1,NOX4,MMP12,NPSR1,AURKB,ALOX15
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
GRIA2,CDK1,MMP12,AURKB,CA12,SLC1A1,GRM8
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
GRM5,AKR1C3,MMP12,AHR,NOX4,GRIA4,GRIN3A
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
FFAR1,KDR,PPARA,DPP4,AURKB,AKR1B1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MET,HIF1A,SRC,TP53,KDR,EGFR
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
GRIK1,GRIN2B,GRM2
NCT00004758,NCT02318446,NCT02369822 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
TP53,CDK1,AURKB,FLT3,SRC,DPP4
|
NADisease Category: NADisease ICD-11 Code: NA |
NOX4,MET
NCT00071266,NCT00781196,NCT04553666,NCT00062556 |
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
EGFR,KDR,TYR,MET,MAPK1
NCT01783431 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MAPK1,SRC,TP53,IGF1R,EGFR,GSTP1
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
ALOX5,KDR,AHR
NCT05025488,NCT00272610,NCT01014546 |
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
GRM2,GRM3
NCT00204932,NCT02612259,NCT01083329,NCT02063802 |
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT00120289,NCT00127218,NCT01221402,NCT00114400,NCT00397657,NCT00150722
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
NCT00157521,NCT00571766,NCT00388856,NCT03451266,NCT00974714 |
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
GRIK1,GRIA2,HSD17B2,CDK1,GRM3,CA12
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
DPP4,GRIN3A,NOX4,FLT3,MMP12,AKR1B1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CDK1,AKR1C3,MMP12,AURKB,CA12,XDH
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CYP2C9,CA2,ALOX15,ADRA2B,CYP1A1,GRM8
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
OR51E2,DPP4,CYP1B1,NOX4,ADRA2B,FFAR4
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA4,GRIN1,CYP2C9,CA12,CA2
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
TP53,SRC
NCT00703196,NCT00220532,NCT00284427 |
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
GRIN1
NCT00170404,NCT01936831,NCT01785186,NCT02563327 |
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
DPP4,NFKB1,PPARA
NCT02107976,NCT02297399 |
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
MET,EGFR,KDR,TP53
NCT01183065 |
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
CA2,XDH
NCT01005303,NCT04703361,NCT01115504 |
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
AKR1C3,AURKB
NCT00216099,NCT01607879,NCT05501548 |
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
GRIK1,GRIN2B,GRIN2A,GRIA1,GRIN1
|
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
GRIN2B
NCT03450707,NCT04921189,NCT03509662,NCT03640949 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
DPP4
NCT03516903,NCT00120289,NCT00000541,NCT00000482 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
NCT00120822,NCT02878265,NCT02699099,NCT00147368,NCT00616304
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
NCT01685281,NCT02189772,NCT00995085,NCT01243242,NCT02086864
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
NCT03148236,NCT00953212,NCT01580683,NCT01107730 |
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
KDR,SRC,TP53,FLT3
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
MET,TP53,HCAR2,DPP4
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA2,CA4,MET,AKR1B1
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
TP53,MET,EGFR,KDR
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
KDR,MET,EGFR,MMP12
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
EGFR,FLT3,GRIN2B,KDR
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
EGFR,TP53,AXL,SRC
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NFKB1,ALOX5,AHR,CYP3A4
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4,GRM5
NCT00325572,NCT00672360 |
Iron deficiency anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00 |
NCT04268849,NCT02541708,NCT03481790,NCT03188445
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT00152893,NCT02773147,NCT02018965,NCT01949116
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
HCAR2,MMP12,GRIN3A
NCT00275418 |
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT00300352,NCT00134433,NCT04907253,NCT03943459
|
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT05457959,NCT01502280,NCT01891747,NCT01792310
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
CYP2C9,ADRA2B,PIM1,GRIK1
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
HCAR2,MMP12,GRIN3A,NOX4
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
GRM1,GRIA1,CA4,ABCG2
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
FLT3,FFAR1,MET,AXL
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
HCAR2,MET,AXL,HSD17B2
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
CA2,AKR1B1,ALOX5,NFKB1,ABCG2
NCT02930343,NCT01711359,NCT00243412,NCT02833350,NCT01217814,NCT00578305,NCT00299130,NCT02379091,NCT01873443,NCT02467504,NCT02504671,NCT02093026,NCT00298272,NCT01061736,NCT00965653,NCT02795299,NCT04535427,NCT00950989,NCT01010581,NCT03028467,NCT03172325,NCT02762838,NCT02393378,NCT00299104,NCT01850680,NCT01116141,NCT00266227,NCT02293902,NCT05363917 |
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
CYP2C9,GRIK3,CISD1,RECQL,FABP3,GRM8,LMNA,OR51E2,ABCG2,DPP4,HSD17B2,ALOX5,CYP1B1,APP,SNCA,ALOX15,CA7,AXL,AKR1C3,SLC1A1,CA2,HCAR2,XDH,PIM1,FFAR4,POLB,GSTP1,MET,NR1I2,NPSR1,AURKB,HIF1A
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
GRIA1,GRIK3,CISD1,FFAR1,GRM8,GRIK1,DPP4,HSD17B2,GRM3,ALOX15,FABP5,CA7,GRIA4,GRIN3A,GRM1,YES1,TP53,CA2,HCAR2,XDH,FFAR4,POLB,GSTP1,MET,NR1I2,MMP12,NPSR1,AURKB,CYP19A1,AKR1B1,HSD17B10
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
YES1,EGFR,CA2,APP,HIF1A,XDH,KDR,MKNK2,MAPK1,FLT3,CA12,ALOX5,CDK1,AHR,MKNK1,CA4,TP53,AURKB,IGF1R,CYP3A4,AXL,NFKB1,PPARA,GSTP1,PIM1,SRC,POLB,MET,CSNK2A1,GSK3B
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CDK1,TYR,FFAR1,RECQL,LMNA,OR51E2,GRIK1,DPP4,HSD17B2,ALOX5,SNCA,ALOX15,CA7,EGFR,AXL,SRC,KDR,CSNK2A2,SLC1A1,HCAR2,XDH,PIM1,FLT3,FFAR4,GSTP1,MET,MMP12,AHR,AURKB,CA12
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
EGFR,MET
NCT01587261 |
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
SRC,GSK3B,FLT3
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
ALOX5,FFAR1,FLT3
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
GRIN2B,GRM3,GRM2
|
Obsessive-compulsive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B20 |
GRIN1
NCT01031927,NCT03356483 |
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
KDR,MET,SRC
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2,CA4,CA12
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
GRM2,GRM5,CYP3A4
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
ALOX5,EGFR,CDK1
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
MET,KDR,EGFR
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
XDH,ALOX5
NCT02735707 |
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
TP53,SRC
NCT01188876 |
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
PPARA
FABP4 NCT02541045 |
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
NCT00807807,NCT00000600 |
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1,ABCG2
NCT04364750 |
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
HCAR2,GRIN2B
NCT00796887 |
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT00338221,NCT00396500,NCT00133562
|
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT03697239,NCT03410030,NCT03908333
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
NCT00575848,NCT00222235,NCT00817336
|
Neuropathy, ataxia, and retinitis pigmentosaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C73.1 |
NCT00065455,NCT00000114,NCT00000116
|
Vitamin C deficiency, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B56.Z |
NCT02606773,NCT03224572,NCT05009355
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT02586285,NCT01287585,NCT05281926
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT00000152,NCT00000161,NCT05062486
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
NCT01118624,NCT04616248,NCT03606967
|
Mixed hyperlipidaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.2 |
NCT00289900,NCT00269204,NCT00269217
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FFAR4,MMP12
NCT03268733 |
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
NCT01852890,NCT03541486 |
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01417481,NCT01348204,NCT00405665
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03580616,NCT03427086,NCT01835782
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
HCAR2,CYP1A1,CDK1
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
NR1I2,AURKB,ABCG2
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1,GRM8,GRM1
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
GRM1,GRM8,ABCG2
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,GRM2,ABCG2
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
CDK1,GRIK3,CISD1,FFAR1,RECQL,FABP3,FABP4,GRM8,LMNA,OR51E2,PPARA,FABP5,EGFR,GRIN3A,CA12,AXL,SRC,KDR,CSNK2A2,TP53,NOX4,GSTP1,MET,NR1I2,AHR,AURKB,AKR1B1,HSD17B10
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
GRIK3,CISD1,CYP1A2,FABP3,GRIA2,HSD17B2,ALOX5,ALOX15,FABP5,CA12,GRM1,YES1,GRIK5,ALOX12,TP53,SLC1A1,CA2,HCAR2,NOX4,XDH,CSNK2A3,FFAR4,GSTP1,MET,NR1I2,MMP12,AHR
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
CYP2C9,SLCO1B1,CDK1,MAPK1,FABP3,ABCG2,DPP4,HSD17B2,ALOX5,APP,SNCA,FABP5,CA12,KDR,CA4,ALOX12,SLC1A1,NOX4,XDH,HIF1A,MET,AHR,NPSR1,AKR1B1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04357782,NCT04900415,NCT04446104,NCT04347889,NCT04928495,NCT04853199,NCT04335084,NCT04370288,NCT04401150,NCT04328961,NCT04703036,NCT03680274,NCT04482686,NCT04354428,NCT02735707,NCT04631536,NCT04851821,NCT05283954,NCT05029037,NCT04363216,NCT04395768,NCT04344184,NCT04334512
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
GRIA1,GRIK3,GRM8,OR51E2,GRIK1,GRIA2,APP,SNCA,FABP5,GRIA4,GRIN3A,GRM1,GRIK5,CA4,GRM2,SLC1A1,CA2,NOX4,XDH,MET,MMP12
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
TP53,IGF1R,FLT3,KDR,EGFR,MKNK1,MKNK2,GSTP1,MET
NCT04516681,NCT01426490,NCT04337879,NCT02066688,NCT00002650,NCT00973609,NCT00611000,NCT00096330,NCT01661764,NCT00070434,NCT02969681 |
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
IGF1R,AKR1B1,GRIK1,ADRA2B,ALOX5
NCT00631111,NCT03082001,NCT03446456,NCT00949104,NCT01796678,NCT03272594,NCT00482560,NCT01561547,NCT03745963,NCT00519207,NCT02990364,NCT01190995,NCT01201954,NCT01503060,NCT02174705 |
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CDK1,LMNA,OR51E2,IGF1R,ALOX5,FABP5,GRM5,SRC,GRIK5,CA4,GRM2,ALOX12,TP53,NOX4,CSNK2A3,HIF1A,GSTP1,MMP12,AURKB,AKR1B1
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CYP2C9,TYR,GRM8,CYP19A1,ALOX5,FABP5,GRM5,XDH,FFAR4,MET,AURKB,OR51E2,FFAR4,GRIK3,MMP12,ALOX5,AURKB,FABP5,GRIA4,GRM8
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
OR51E2,GRIA2,CA12,FABP5,CDK1,AKR1C3,GRM2,CA4,MMP12,AURKB,NOX4,CYP19A1,FABP4,CA12,CDK1,SRC,AKR1C3,MMP12,AURKB,CYP19A1
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
ALOX5,SRC
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1,ALOX5
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
SRC,KDR
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
GRIK1,ADRA2B
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
GRM3,GRM2
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
GRIK1,ADRA2B
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
IGF1R,ALOX5
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
KDR,SRC
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
PPARA,HCAR2
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
NCT00000161 |
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC,GSK3B
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
NCT00154700 |
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH,PPARA
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
MET,KDR
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
SRC,EGFR
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
GRM2
NCT01720316 |
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
GRM5,GSK3B
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
CDK1,FLT3
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
FLT3
NCT04898023 |
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
TP53,SRC
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
IGF1R,SRC
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARA,HCAR2
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
APP,IGF1R
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
NCT00573313 |
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
SRC,FLT3
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT00300365 |
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
NCT00137124 |
Other specified infectious meningitis not elsewhere classifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.Y |
NCT05289908,NCT03101579
|
Primary neoplasms of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
NCT01188096,NCT03068832
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
NCT02678234,NCT02730364
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT04630964,NCT03866174
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02730949,NCT02109315
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT02702492,NCT00626444
|
Asymptomatic stenosis of intracranial or extracranial arteryDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD55 |
NCT00000600,NCT00000599
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT02083575,NCT00006136
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT01388764,NCT02516085
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT00475176,NCT01438320
|
Tuberculosis of the respiratory systemDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10 |
NCT00677339,NCT03882177
|
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
NCT04345705,NCT01569919
|
Cleft lipDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA40 |
NCT00098319,NCT00397917
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT04946383,NCT05422885
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT02618824,NCT03088345
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT04046094,NCT03359239
|
FlushingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64.4 |
NCT00536237,NCT00533611
|
Dental cariesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08.0 |
NCT04750902,NCT02388178
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
NCT00406874,NCT01407432
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
NCT03015675 |
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00052715,NCT00058123
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT05378919,NCT04801511
|
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT02868151,NCT03581773
|
Peripheral T-cell lymphoma, not otherwise specifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90.C |
NCT02106650,NCT02013362
|
AsphyxiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.1 |
NCT03066115,NCT04357782
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT05276895,NCT04783792
|
Cerebrovascular diseases, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B2Z |
NCT00000599,NCT00000600
|
Cleft palateDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA42 |
NCT00397917,NCT00098319
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT04404387,NCT03718507
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT02186158,NCT02735707
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
NCT04261036,NCT03800667
|
Schizophrenia or other primary psychotic disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A2Z |
NCT01720095,NCT00202280
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT02793648,NCT00480207
|
Cutaneous T-cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1951 |
NCT00554827,NCT02061449
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
NCT05452772,NCT00067899
|
FatigueDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG22 |
NCT02521077,NCT00633581
|
Spina bifida, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA02.Z |
NCT00301587,NCT00452829
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
NCT03522922,NCT03090048
|
Retinal vascular occlusionDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B74 |
NCT00500045,NCT00493064
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT01014546,NCT05025488
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00005107,NCT00344916
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT03752918,NCT00215878
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
NCT03121677,NCT00455416
|
Noise effects on inner earDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB37 |
NCT01345474,NCT02903355
|
Other specified haemorrhagic or haematological disorders of fetus or newbornDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA8Y |
NCT02075970,NCT00731588
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00344734,NCT00787059
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT03989271,NCT01708278
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
MMP12,DPP4
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
NOX4,FABP4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
MMP12,CYP1A1
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
HCAR2,MET
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CDK1,GRIA1,FABP3,FABP4,OR51E2,GRIA2,IGF1R,GRM3,FABP5,CA12,GRM1,SRC,CA4,NOX4,GSTP1,MMP12,AURKB,CYP19A1,AKR1B1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CDK1,FFAR1,FABP3,OR51E2,CYP19A1,CYP3A4,DPP4,HSD17B2,SNCA,FABP5,CA7,GRM1,CA4,SLC1A1,NOX4,MET,MMP12,AURKB,CA12
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
AXL,SRC,AHR,FLT3,IGF1R,KDR
NCT00227682,NCT00469209,NCT00317811,NCT00006021,NCT00112879,NCT00258245,NCT03964688,NCT02206425,NCT00661544,NCT03602235,NCT02114502,NCT00085345 |
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
GRM5,GRM3,AKR1B1,GRM2
NCT00575848,NCT00005658,NCT00222235,NCT00276263,NCT00211562,NCT00291226,NCT00929370,NCT00268749,NCT02067975,NCT04054973,NCT00491569,NCT00215917,NCT00000372,NCT00817336 |
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA12,CDK1,CA4,CYP19A1,MKNK1,EGFR,CA2,KDR,SRC,MET,AXL,IGF1R,MKNK2
NCT00908791,NCT02427581,NCT00986609,NCT03175341 |
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
HCAR2,PPARA
NCT00111891,NCT00943124,NCT00664287,NCT00944645,NCT00728910,NCT01984073,NCT00626392,NCT00903617,NCT00961636,NCT00630877,NCT03510884,NCT00376584,NCT01104519,NCT02890992,NCT01071291 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
PPARA,FFAR1,NFKB1,DPP4
NCT00607945,NCT02786823,NCT05210504,NCT03685773,NCT01839344,NCT00618995,NCT02440061,NCT03540758,NCT03437902,NCT01319734,NCT01368328,NCT00485758,NCT02744820 |
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CYP2C9,CISD1,GRIK1,CYP3A4,DPP4,HSD17B2,CYP1B1,ALOX15,FABP5,NFKB1,HCAR2,FLT3,FFAR4,MMP12,AKR1B1,HSD17B10
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CYP2C9,SLCO1B1,CDK1,OR51E2,GRIA2,CA7,GRM1,AKR1C3,ALOX12,ADRA2B,XDH,MMP12,NPSR1,AURKB,CA12
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
EGFR,MET,KDR
NCT00806819,NCT03799094,NCT01194453,NCT00609518,NCT05096663,NCT01165021,NCT02420314,NCT00606502,NCT02655913,NCT03166254,NCT02905591 |
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT00082251,NCT00769132,NCT00378833,NCT00271817,NCT00269217,NCT00533312,NCT00203476,NCT00652431,NCT03510715,NCT01054508,NCT01321034,NCT00080275,NCT01071525,NCT00536510
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
GRIA2,DPP4,GRIK3,MET,MMP12,ALOX5,FFAR1,HCAR2,CYP1B1,NOX4,CA12,CA7,XDH
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CYP2C9,CDK1,GRIK3,GRM8,HSD17B2,ALOX15,CA2,HCAR2,XDH,MMP12,NPSR1,AURKB,CYP1A1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
GSTP1,AXL,ALOX5,MMP12,EGFR,FLT3,MET,CDK1,IGF1R,KDR
NCT00402883,NCT00033722 |
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
APP,MET,GRM2,GRM5,GRM3,FLT3,KDR,SNCA
NCT00056225,NCT01439555,NCT04740580,NCT03062449 |
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
GRIK3,FFAR1,FABP3,GRM8,ABCG2,IGF1R,APP,GRM5,SLC1A1,NOX4,GSTP1,NR1I2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CYP2C9,SLCO1B1,CDK1,CA7,AKR1C3,GRIK5,XDH,NR1I2,MMP12,NPSR1,AURKB,CA12
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
CYP19A1,GRM5,HIF1A,GRM1,AXL,GRIA1,GRIK3,FFAR1,ADRA2B,XDH,EGFR,LMNA
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
GRIK3,LMNA,DPP4,CYP1B1,FABP5,CA12,KDR,CA2,HCAR2,CSNK2A3,MET,CYP19A1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
GRIA1,GRIK3,CYP1A2,GRIK1,CYP3A4,GRM2,HCAR2,CA2,MET,AURKB,CA12,CYP1A1
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NFKB1,PIM1,TP53,AXL,GSK3B,SRC,FLT3,AURKB
NCT01842139,NCT00184054,NCT00329498 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NFKB1,GRIN1,GRIN2B,SRC
NCT02220244,NCT01381354,NCT04764383,NCT02220933,NCT03266965,NCT00638196,NCT02936037 |
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
EGFR,MKNK2,MKNK1,HIF1A
NCT00917826,NCT01983969,NCT02961816,NCT00998946,NCT02589145,NCT02701673 |
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
SLCO1B1,CDK1,GRM8,ALOX15,NOX4,MET,MMP12,NPSR1,AURKB,CYP19A1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
Myotonic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71 |
GSK3B
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Skin sensation disturbanceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME65 |
GRM5
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TP53
|
Alpha-1-antitrypsin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C5A |
GRIN2B
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
APP
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
EGFR
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
GRM5
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
GRM2
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Dystrophic epidermolysis bullosaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC32 |
APP
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
FLT3
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MAPK1
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Desmoid tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7C |
APP
|
Diagnostic imagingDisease Category: NADisease ICD-11 Code: N.A. |
APP
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
AKR1C3
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NFKB1
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
AXL
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
TYR
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
HIF1A
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53
|
Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
GRM5
|
Ureteral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C92 |
AHR
|
Acquired hypermelanosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60 |
TYR
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
FLT3
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
GRIN2A
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT00763633
|
AnorexiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43.7 |
NCT01295450
|
Polycythaemia veraDisease Category: X.Extension CodesDisease ICD-11 Code: XH0453 |
NCT01014546
|
Pulmonary alveolar proteinosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB04.31 |
NCT03887169
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT00855257
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT01953536
|
Inflammatory carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C62 |
NCT00986609
|
Infectious gastroenteritis or colitis without specification of infectious agentDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A40.Z |
NCT00133406
|
Sezary syndromeDisease Category: X.Extension CodesDisease ICD-11 Code: XH8HN3 |
NCT01134341
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT02929888
|
Noninfectious erosive or ulcerative disorders of oral mucosaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01.1 |
NCT04989049
|
Harmful effects of drugs, medicaments or biological substances, not elsewhere classifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE60 |
NCT02908581
|
Flare or flashDisease Category: X.Extension CodesDisease ICD-11 Code: XE03F |
NCT01140646
|
Acute viral hepatitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50 |
NCT00108589
|
Recurrent pregnancy lossDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA33 |
NCT01976676
|
Malignant neoplasm metastasis in male genital organsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E06 |
NCT02516670
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT01550510
|
Carcinomas of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.0 |
NCT03162562
|
Other specified syndromes with multiple structural anomalies, not of environmental originDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F.1Y |
NCT00446147
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
NCT00120289
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT04035096
|
Abdominal pelvic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD81 |
NCT00694564
|
Human immunodeficiency virus type 1Disease Category: X.Extension CodesDisease ICD-11 Code: XN8LD |
NCT01426438
|
Malignant neoplasms of retroperitoneumDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C50 |
NCT01188876
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT04249336
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
Rhabdomyosarcoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0GA1 |
NCT01871766
|
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT00136188
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT01266018
|
Anterior uveitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A96 |
NCT01900431
|
Injury of lung, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NB32.3Z |
NCT04344184
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02424201
|
ShockDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG40 |
NCT01587963
|
MelasmaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60.1 |
NCT01603446
|
CraniopharyngiomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1AZ2 |
NCT01419067
|
Oligodendroglioma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH8844 |
NCT02168270
|
Aortic valve stenosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB70 |
NCT02109614
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT02602483
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00200746
|
Vitamin A deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55 |
NCT00128557
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT01436266
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT04478734
|
Acute promyelocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1A50 |
NCT03624270
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT00000324
|
Burn and burn infectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND90-NE2Z |
NCT00734695
|
GliosarcomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH9RC8 |
NCT02168270
|
Movement disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A07-8A0Z |
NCT01908452
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03861416
|
Hereditary sensory or autonomic neuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.Z |
NCT00271635
|
Macro reentrant atrial tachycardia, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.2Z |
NCT00953212
|
Argininosuccinic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.A0 |
NCT00345605
|
Mild hyperemesis gravidarumDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA60.0 |
NCT00861523
|
Duplications of the short arm of chromosome 17Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD41.G1 |
NCT00484510
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT00133419
|
Uterine fibroidDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E66 |
NCT01715597
|
Astrocytoma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH96C7 |
NCT02168270
|
Disorders of muscles, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB3Z |
NCT03223519
|
MenopauseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.0 |
NCT00000555
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02756117
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04482686
|
Ependymoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1511 |
NCT02125786
|
Anaplastic large cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1LC0 |
NCT01134341
|
Mycosis fungoidesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B01 |
NCT01134341
|
Basal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C32 |
NCT04279535
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT05042024
|
Other specified disorders of carbohydrate absorption or transportDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C61.Y |
NCT02291458
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT03493178
|
Circadian rhythm sleep disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A60-7A65 |
NCT01468038
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT01985685
|
Clear cell renal cell carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH46F1 |
NCT03334409
|
Soft tissue disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB56 |
NCT03508726
|
Galactose-1-phosphate uridyltransferase deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C51.40 |
NCT03580122
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT03418038
|
Atherosclerotic chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD40.Z |
NCT00804843
|
Retinopathy of prematurityDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71.3 |
NCT01238471
|
Parasitic infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D0Y-1G2Z |
NCT00396500
|
BeriberiDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5A.0 |
NCT01864057
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT00634998
|
Infantile spasmsDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62.0 |
NCT01828437
|
Carcinoma of male breastDisease Category: X.Extension CodesDisease ICD-11 Code: XH5KW8 |
NCT01042535
|
Diabetic lactic acidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A22.1 |
NCT00143702
|
Melanoma of skin, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30.Z |
NCT02129075
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
NCT04855266
|
Complex regional pain syndromeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30.04 |
NCT02390505
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT00218946
|
Hereditary sensory and autonomic neuropathy type IDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.0 |
NCT01733407
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
AXL
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
MMP12
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
HCAR2
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
Plant-Targeted Human Disease Network
>> Targets derived from weak experimental activities
