Alterative; Antispasmodic; Aphrodisiac; Demulcent; Digestive; Diuretic; Galactogogue; Infertility; Women's complaints
Madagascar; Bangladesh; Liberia; Sudan; Guinea; Nepal; Cambodia; Ethiopia; Rwanda; Somalia; Nigeria; Cote d'Ivoire; Ghana; Australia; Burkina Faso; Togo; Zimbabwe; China; Thailand; Sierra Leone; Eritrea; Maldives; Pakistan; Oman; Tanzania; Indonesia; Mauritius; Trinidad and Tobago; Vietnam; Gabon; Guinea-Bissau; Mali; Yemen; Jamaica; Angola; Myanmar; Equatorial Guinea; India; Mozambique; Uganda; Sri Lanka; Kenya
Ingredient ID: NPC95126
Ingredient ID: NPC7964
Ingredient ID: NPC72661
Ingredient ID: NPC43293
Ingredient ID: NPC38807
Ingredient ID: NPC3417
Ingredient ID: NPC309399
Ingredient ID: NPC290445
Ingredient ID: NPC283908
Ingredient ID: NPC27669
Ingredient ID: NPC269923
Ingredient ID: NPC265513
Ingredient ID: NPC249340
Ingredient ID: NPC247282
Ingredient ID: NPC245265
Ingredient ID: NPC235204
Ingredient ID: NPC221275
Ingredient ID: NPC220596
Ingredient ID: NPC213755
Ingredient ID: NPC19856
Ingredient ID: NPC165711
Ingredient ID: NPC157923
Ingredient ID: NPC149293
Ingredient ID: NPC113614
Ingredient ID: NPC105141
Ingredient ID: NPC101849
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Enzyme | KARS1 | Lysyl-tRNA synthetase | Q15046 | CHEMBL5575 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
Plant level | 1 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT05025917 | Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women | Muscle Weakness|Osteoporosis;Postmenopausal | Asparagus Racemosus | Plant level As single plant |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Other specified disorders of musclesDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB32.Y |
NCT05025917
|
Postmenopausal osteoporosisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.11 |
NCT05025917
|