Collective Molecular Activities of the Plant: Theobroma Cacao
Example Image
PLANiTS DNA barcode
Taxonomic Information
Used in Medicines
Country/Region:
Ghana; Brazil; Philippines; India; Papua New Guinea; China; Sri Lanka; Nigeria; Bolivia; Venezuela; EcuadorTraditional Medicine System:
Indian Folk; TCM; SiddhaGeographical Distribution
Brazil; Guinea; Peru; Nigeria; Bolivia; Cameroon; Cote d'Ivoire; Ecuador; Ghana; Cuba; El Salvador; Venezuela; Papua New Guinea; Togo; Guatemala; China; Haiti; Belize; Philippines; United States; Trinidad and Tobago; French Guiana; Dominican Republic; Jamaica; Seychelles; Honduras; Mexico; India; Colombia; Sri Lanka; Fiji
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary
Overview of Ingredients
123 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
73 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
86 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC99734
Ingredient ID: NPC94167
Ingredient ID: NPC93888
Ingredient ID: NPC85813
Ingredient ID: NPC85488
Ingredient ID: NPC80302
Ingredient ID: NPC76662
Ingredient ID: NPC75384
Ingredient ID: NPC73219
Ingredient ID: NPC70744
Ingredient ID: NPC69445
Ingredient ID: NPC6913
Ingredient ID: NPC68938
Ingredient ID: NPC62765
Ingredient ID: NPC62045
Ingredient ID: NPC58064
Ingredient ID: NPC55412
Ingredient ID: NPC50880
Ingredient ID: NPC490378
Ingredient ID: NPC490353
Ingredient ID: NPC489908
Ingredient ID: NPC489907
Ingredient ID: NPC489899
Ingredient ID: NPC470831
Ingredient ID: NPC46335
Ingredient ID: NPC424
Ingredient ID: NPC38343
Ingredient ID: NPC33338
Ingredient ID: NPC328447
Ingredient ID: NPC317120
Ingredient ID: NPC314243
Ingredient ID: NPC314184
Ingredient ID: NPC310342
Ingredient ID: NPC306397
Ingredient ID: NPC305307
Ingredient ID: NPC303422
Ingredient ID: NPC302857
Ingredient ID: NPC301696
Ingredient ID: NPC295644
Ingredient ID: NPC294558
Ingredient ID: NPC287695
Ingredient ID: NPC286956
Ingredient ID: NPC28657
Ingredient ID: NPC282812
Ingredient ID: NPC281686
Ingredient ID: NPC280254
Ingredient ID: NPC279406
Ingredient ID: NPC279026
Ingredient ID: NPC278906
Ingredient ID: NPC277510
Ingredient ID: NPC272614
Ingredient ID: NPC272552
Ingredient ID: NPC269919
Ingredient ID: NPC264084
Ingredient ID: NPC261831
Ingredient ID: NPC261324
Ingredient ID: NPC256849
Ingredient ID: NPC255246
Ingredient ID: NPC252603
Ingredient ID: NPC248007
Ingredient ID: NPC242580
Ingredient ID: NPC237812
Ingredient ID: NPC236202
Ingredient ID: NPC234222
Ingredient ID: NPC227491
Ingredient ID: NPC226453
Ingredient ID: NPC226315
Ingredient ID: NPC226108
Ingredient ID: NPC224161
Ingredient ID: NPC223548
Ingredient ID: NPC220825
Ingredient ID: NPC219876
Ingredient ID: NPC214702
Ingredient ID: NPC208793
Ingredient ID: NPC20791
Ingredient ID: NPC204932
Ingredient ID: NPC203719
Ingredient ID: NPC203468
Ingredient ID: NPC201844
Ingredient ID: NPC196512
Ingredient ID: NPC195952
Ingredient ID: NPC189436
Ingredient ID: NPC187770
Ingredient ID: NPC185755
Ingredient ID: NPC185392
Ingredient ID: NPC185231
Ingredient ID: NPC180871
Ingredient ID: NPC17810
Ingredient ID: NPC175342
Ingredient ID: NPC174246
Ingredient ID: NPC170509
Ingredient ID: NPC1682
Ingredient ID: NPC167400
Ingredient ID: NPC161571
Ingredient ID: NPC160026
Ingredient ID: NPC159451
Ingredient ID: NPC157417
Ingredient ID: NPC156654
Ingredient ID: NPC155263
Ingredient ID: NPC154656
Ingredient ID: NPC154186
Ingredient ID: NPC152451
Ingredient ID: NPC150950
Ingredient ID: NPC147983
Ingredient ID: NPC139940
Ingredient ID: NPC137958
Ingredient ID: NPC136014
Ingredient ID: NPC130683
Ingredient ID: NPC129800
Ingredient ID: NPC126681
Ingredient ID: NPC126029
Ingredient ID: NPC124846
Ingredient ID: NPC119133
Ingredient ID: NPC118284
Ingredient ID: NPC11433
Ingredient ID: NPC112890
Ingredient ID: NPC112318
Ingredient ID: NPC111888
Ingredient ID: NPC110899
Ingredient ID: NPC11016
Ingredient ID: NPC108811
Ingredient ID: NPC107522
Ingredient ID: NPC100980
Classification of Human Proteins Collectively Targeted by the Plant
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2B6 | Cytochrome P450 2B6 | P20813 | CHEMBL4729 |
| Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
| Therapeutic Target | Enzyme | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | P05186 | CHEMBL5979 |
| Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
| Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
| Therapeutic Target | Enzyme | AKR1C3 | Aldo-keto-reductase family 1 member C3 | P42330 | CHEMBL4681 |
| Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
| Therapeutic Target | Fatty acid binding protein family | FABP5 | Fatty acid binding protein epidermal | Q01469 | CHEMBL3674 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK5 | Glutamate receptor ionotropic kainate 5 | Q16478 | CHEMBL2675 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK3 | Glutamate receptor ionotropic kainate 3 | Q13003 | CHEMBL3684 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIA4 | Glutamate receptor ionotropic, AMPA 4 | P48058 | CHEMBL3190 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK1 | Glutamate receptor ionotropic kainate 1 | P39086 | CHEMBL1918 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lyase | CA6 | Carbonic anhydrase VI | P23280 | CHEMBL3025 |
| Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
| Therapeutic Target | Membrane receptor | APP | Beta amyloid A4 protein | P05067 | CHEMBL2487 |
| Therapeutic Target | Nuclear hormone receptor subfamily 1 | PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 | CHEMBL239 |
| Therapeutic Target | Nuclear hormone receptor subfamily 1 | RORC | Nuclear receptor ROR-gamma | P51449 | CHEMBL1741186 |
| Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
| Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
| Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Oxidoreductase | PTGS2 | Cyclooxygenase-2 | P35354 | CHEMBL230 |
| Therapeutic Target | Oxidoreductase | NQO2 | Quinone reductase 2 | P16083 | CHEMBL3959 |
| Therapeutic Target | Oxidoreductase | AOX1 | Aldehyde oxidase | Q06278 | CHEMBL3257 |
| Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
| Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
| Therapeutic Target | Protein Kinase | SRC | Tyrosine-protein kinase SRC | P12931 | CHEMBL267 |
| Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
| Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
| Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
| Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
| Therapeutic Target | Protein Kinase | PTK2 | Focal adhesion kinase 1 | Q05397 | CHEMBL2695 |
| Therapeutic Target | Protein Kinase | FYN | Tyrosine-protein kinase FYN | P06241 | CHEMBL1841 |
| Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
| Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
| Therapeutic Target | Protein Kinase | MAPK1 | MAP kinase ERK2 | P28482 | CHEMBL4040 |
| Therapeutic Target | Protein Kinase | ALK | ALK tyrosine kinase receptor | Q9UM73 | CHEMBL4247 |
| Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
| Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A2 | Norepinephrine transporter | P23975 | CHEMBL222 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A4 | Serotonin transporter | P31645 | CHEMBL228 |
| Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A3 | Dopamine transporter | Q01959 | CHEMBL238 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HCAR2 | Hydroxycarboxylic acid receptor 2 | Q8TDS4 | CHEMBL3785 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2B | Alpha-2b adrenergic receptor | P18089 | CHEMBL1942 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR1 | Free fatty acid receptor 1 | O14842 | CHEMBL4422 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | DRD3 | Dopamine D3 receptor | P35462 | CHEMBL234 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR4 | G-protein coupled receptor 120 | Q5NUL3 | CHEMBL5339 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM1 | Metabotropic glutamate receptor 1 | Q13255 | CHEMBL3772 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM8 | Metabotropic glutamate receptor 8 | O00222 | CHEMBL3228 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
| Therapeutic Target | Transferase | GSTP1 | Glutathione S-transferase Pi | P09211 | CHEMBL3902 |
| Therapeutic Target | Transferase | SULT1A1 | Sulfotransferase 1A1 | P50225 | CHEMBL1743291 |
| Therapeutic Target | Transferase | PIK3CB | PI3-kinase p110-beta subunit | P42338 | CHEMBL3145 |
| Therapeutic Target | Transferase | PIK3CA | PI3-kinase p110-alpha subunit | P42336 | CHEMBL4005 |
| Therapeutic Target | Transient receptor potential channel | TRPA1 | Transient receptor potential cation channel subfamily A member 1 | O75762 | CHEMBL6007 |
| Therapeutic Target | Unclassified protein | SNCA | Alpha-synuclein | P37840 | CHEMBL6152 |
Clinical Trials Summary
Overview
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 756 | |
 Plant level | 10 | |
Clinical trial details
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT02594358 | Caffeine in Amblyopia Study | amblyopia | Caffeine (NPC256849) | NP level |
| NCT00120822 | Folic Acid Supplementation in Gambian Primigravidae | malaria | Folic Acid (NPC147983) | NP level |
| NCT00272610 | Topical Vitamin A Versus Vehicle Cream in the Treatment of Aged Skin | Purpura | Retinol (NPC55412) | NP level |
| NCT01989897 | Effect of HSA or Saline Diluent on Immunotherapy Extract Stability as Determined by Graded ID Skin Tests | allergic rhinitis | Phenol (NPC100980) | NP level |
| NCT02990364 | Combination Analgesia for Neonatal Circumcision | pain | Sucrose (NPC130683) | NP level |
| NCT04952051 | Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension | hypertension | Folic Acid (NPC147983) | NP level |
| NCT01468415 | Efficiency Comparison Between Methylprednisolone and Phenol 8% Treatment Using a Trans Sacral Approach - on Lower Back Pain and Limbs | Back pain | Phenol (NPC100980) | NP level |
| NCT03095105 | Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT01566565 | The Safety Evaluation of Drug Combinations Against High Altitude Pulmonary Hypertension | pulmonary arterial hypertension | Theophylline (NPC252603) | NP level |
| NCT03446456 | Vasopressin and Pain Perception in the Brain | pain | Arginine (NPC226453) | NP level |
| NCT04872270 | Pain Management After Shoulder Arthroplasty | pain | Caffeine (NPC256849) | NP level |
| NCT00567931 | 1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT03101579 | Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT01561547 | Trial of Repeated Analgesia With Kangaroo Care | pain | Sucrose (NPC130683) | NP level |
| NCT01289561 | Combined Effects of Alcohol and Caffeine | alcohol dependence | Caffeine (NPC256849) | NP level |
| NCT03068832 | Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT01287585 | Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy | hepatocellular carcinoma | Arginine (NPC226453) | NP level |
| NCT04740580 | Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease | Alzheimer disease | Glycine (NPC126681) | NP level |
| NCT00006021 | Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03029429 | Theophylline Treatment for Pseudohypoparathyroidism | Albright hereditary osteodystrophy;pseudohypoparathyroidism | Theophylline (NPC252603) | NP level |
| NCT00137124 | L-Arginine Metabolism in Essential Hypertension | essential hypertension | Arginine (NPC226453) | NP level |
| NCT04132336 | Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed | pain | Caffeine (NPC256849) | NP level |
| NCT00930306 | AZD2066 Cocktail Study | Chronic pain | Caffeine (NPC256849) | NP level |
| NCT00571766 | Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT03624270 | Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia | acute promyelocytic leukemia | Ascorbate (NPC187770) | NP level |
| NCT01999829 | Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo | atrial fibrillation | Caffeine (NPC256849) | NP level |
| NCT03718507 | Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants | acute respiratory distress syndrome | Sucrose (NPC130683) | NP level |
| NCT03437902 | Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00796887 | Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery | Ischemic stroke | Niacin (NPC167400) | NP level |
| NCT00263471 | Myopia Progression and the Effect of 7-Methylxanthine | Myopia | 7-Methylguanine (NPC248007) | NP level |
| NCT04631536 | Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC | COVID-19 | Folic Acid (NPC147983);Arginine (NPC226453) | NP level |
| NCT04425902 | Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults | HIV infection | Caffeine (NPC256849) | NP level |
| NCT00065455 | Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT00047983 | Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant Patients | kidney disease | Arginine (NPC226453) | NP level |
| NCT01828437 | Addition of Pyridoxine to Prednisolone in Infantile Spasms | West syndrome | Pyridoxine (NPC269919) | NP level |
| NCT00291226 | Glycine vs Placebo for the Schizophrenia Prodrome | schizophrenia | Glycine (NPC126681) | NP level |
| NCT00127218 | High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT01590303 | Outcome Following Vitamin C Administration in Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT01165021 | A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01014546 | Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis | essential thrombocythemia;polycythemia vera;primary myelofibrosis | Ascorbate (NPC187770) | NP level |
| NCT04843553 | Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients | actinic keratosis | Niacinamide (NPC306397) | NP level |
| NCT00998946 | Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma | lymphoma | Folic Acid (NPC147983) | NP level |
| NCT04328961 | Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP) | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03358706 | A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis | Crohn's disease;ulcerative colitis | Caffeine (NPC256849) | NP level |
| NCT01873443 | Long-Term Efficacy and Safety of CT-P10 in Patients With RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00272844 | Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome | Smith-Lemli-Opitz syndrome | Cholesterol (NPC28657) | NP level |
| NCT02061449 | Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma | Cutaneous T-cell lymphoma | Lysine (NPC112890) | NP level |
| NCT02293902 | A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04630964 | The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT00519207 | Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture | pain | Sucrose (NPC130683) | NP level |
| NCT01891747 | A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma | malignant glioma | Ascorbate (NPC187770) | NP level |
| NCT01492114 | Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults. | inflammation | Resveratrol (NPC161571) | NP level |
| NCT04703036 | Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19 | COVID-19 | Glycine (NPC126681) | NP level |
| NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT02890992 | An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01134341 | Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | anaplastic large cell lymphoma;mycosis fungoides;Sezary's disease | Folic Acid (NPC147983) | NP level |
| NCT05485805 | A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo | toothache | Caffeine (NPC256849) | NP level |
| NCT00000116 | Randomized Trial of DHA for Retinitis Pigmentosa Patients Receiving Vitamin A | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT00408577 | Prevention of Cardiac and Vascular Events in Patients With NGT/IGT. | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT04400890 | Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol, a Plant Polyphenol, for COVID-19 | COVID-19 | Resveratrol (NPC161571) | NP level |
| NCT00000114 | Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT01435837 | Interaction of Caffeine and Hydration on Voice | voice disorders | Caffeine (NPC256849) | NP level |
| NCT00216099 | Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer | prostate cancer | Folic Acid (NPC147983) | NP level |
| NCT00677339 | L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) | pulmonary tuberculosis | Arginine (NPC226453) | NP level |
| NCT01856868 | Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study) | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
| NCT00317811 | Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01188876 | Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer | fallopian tube cancer;ovarian cancer;peritoneum cancer | Folic Acid (NPC147983) | NP level |
| NCT05025488 | Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm | essential thrombocythemia;myelofibrosis | Lysine (NPC112890) | NP level |
| NCT00200746 | Treatment of Alcohol-Related Hepatitis With Arginine | Hepatitis, Alcoholic | Arginine (NPC226453) | NP level |
| NCT04370288 | Clinical Application of Methylene Blue for Treatment of Covid-19 Patients | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03481790 | Lactoferrin Versus Ferrous Sulphate for Treatment of Iron Deficiency Anaemia During Pregnancy | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT01439555 | Endothelial Facilitation in Alzheimer's Disease | Alzheimer disease | Arginine (NPC226453) | NP level |
| NCT04703361 | Effects of Ketones and Niacin in Heart Failure Patients | systolic heart failure | Niacin (NPC167400) | NP level |
| NCT02344355 | A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT04201873 | Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT00143702 | D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE) | lactic acidosis | Thiamine (NPC150950) | NP level |
| NCT04482686 | Trial of Combination Therapy to Treat COVID-19 Infection | COVID-19;severe acute respiratory syndrome | Ascorbate (NPC187770) | NP level |
| NCT02730949 | D-chiro-Inositol in Overweight Type 1 Diabetes Patients | type 1 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT01651793 | Effect of Phytochemicals From Theobroma Cacao on Mental Energy | Mental Fatigue | Theobroma Cacao | Plant level As plant Extract |
| NCT00493064 | To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT00054938 | Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE) | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT00554827 | Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | Cutaneous T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT03370159 | CPI-613 and Docetaxel in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer | non-small cell lung carcinoma | Octanoic Acid (NPC301696) | NP level |
| NCT04395768 | International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer | rectum cancer | Ascorbate (NPC187770) | NP level |
| NCT01905150 | Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
| NCT02537691 | Longitudinal Cohort Study in Participants With Severe Asthma to Assess Biomarkers | asthma | Theophylline (NPC252603) | NP level |
| NCT01636557 | A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Caffeine (NPC256849) | NP level |
| NCT01555489 | Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT04921189 | Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors | cardiac arrest | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT00508989 | Niacin to Improve Blood Flow in People With Sickle Cell Disease | sickle cell anemia | Niacin (NPC167400) | NP level |
| NCT00929370 | A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam. | schizophrenia | Glycine (NPC126681) | NP level |
| NCT02833701 | Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT03236662 | (-)- Epicatechin Becker Muscular Dystrophy | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
| NCT01914081 | Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside | dilated cardiomyopathy | Resveratrol (NPC161571) | NP level |
| NCT01221402 | Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT00082251 | Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01130727 | The Effect of Green Tea or Cocoa Extracts in Endothelial Dysfunction in Patients With Diabetes Mellitus | Diabetes Mellitus|Diabetic Nephropathy|Arterial Hypertension | Theobroma Cacao | Plant level As plant Extract |
| NCT00953212 | Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery | atrial fibrillation;atrial flutter | Ascorbate (NPC187770) | NP level |
| NCT05281926 | A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients | hepatocellular carcinoma | Lysine (NPC112890) | NP level |
| NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT00728910 | Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00252785 | Efficacy & Safety of Symbicort® TURBUHALER® 160/4.5 µg Twice Daily & Pulmicort® TURBUHALER® 200 µg Twice Daily + Theolong® Tablet 200 mg Twice Daily in Japanese Asthmatic Patients | asthma | Theophylline (NPC252603) | NP level |
| NCT03768492 | Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy | breast carcinoma | Caffeine (NPC256849) | NP level |
| NCT00638196 | Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS | multiple sclerosis | Oleic Acid (NPC261831) | NP level |
| NCT01188096 | A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT02063802 | Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT00634413 | Effect of ADC4022 Co-Administered With Budesonide on Pulmonary Inflammation in Subjects With Moderate to Severe COPD | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT00661544 | Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03321734 | Intermittent Hypoxia and Caffeine in Infants Born Preterm | hypoxia | Caffeine (NPC256849) | NP level |
| NCT00954525 | Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00508885 | The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT01194453 | Pemetrexed Plus Cisplatin Versus Gemcitabine Plus Cisplatin for Advanced NSCLC Metastatic Non-small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT03752918 | The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. | post-traumatic stress disorder | Niacin (NPC167400) | NP level |
| NCT04900792 | A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT04035096 | The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients | malignant colon neoplasm | Ascorbate (NPC187770) | NP level |
| NCT02390505 | Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery | complex regional pain syndrome | Ascorbate (NPC187770) | NP level |
| NCT01142219 | L-Arginine and Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT04900415 | Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction | COVID-19 | Retinol (NPC55412) | NP level |
| NCT00950989 | Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01104519 | A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02080078 | A Phase I Dose Escalation Study of Erlotinib in Combination With Theophylline | non-small cell lung carcinoma | Theophylline (NPC252603) | NP level |
| NCT03288155 | Can a Flavonoid-rich Pure Cocoa Reduce Fatigue in People With Parkinson's (PD) | Parkinson Disease|Fatigue | Theobroma Cacao | Plant level As single plant |
| NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
| NCT00446147 | Study of Pyridoxine for Hand-Foot Syndrome | Hand-foot syndrome | Pyridoxine (NPC269919) | NP level |
| NCT01629329 | Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT00734695 | Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment. | burn | Ascorbate (NPC187770) | NP level |
| NCT01031927 | N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD) | obsessive-compulsive disorder | Glycine (NPC126681) | NP level |
| NCT04249336 | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH | allergic disease | Arginine (NPC226453) | NP level |
| NCT04335084 | A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02589145 | Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00056225 | VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study) | Alzheimer disease | Pyridoxine (NPC269919);Folic Acid (NPC147983) | NP level |
| NCT02832336 | The Effect of Caffeine on the Narcoleptic Patients | narcolepsy | Caffeine (NPC256849) | NP level |
| NCT03541486 | A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00301587 | A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT00344734 | Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure | congestive heart failure | Arginine (NPC226453) | NP level |
| NCT02018965 | Niacin on Immune Activation : a Proof-of-concept Study | HIV infection | Niacin (NPC167400) | NP level |
| NCT02521077 | Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT02379091 | Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03003000 | Ibuprofen/Caffeine Lower Back or Neck Pain Study | Back pain;Neck pain | Caffeine (NPC256849) | NP level |
| NCT02558595 | Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2) | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT04054973 | L-arginine Study for Persistent Symptoms of Schizophrenia | schizophrenia | Arginine (NPC226453) | NP level |
| NCT03882177 | StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis | pulmonary tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT01426971 | Ibuprofen Versus Ibuprofen Plus Caffeine in the Treatment of Migraine. | pain | Caffeine (NPC256849) | NP level |
| NCT03028467 | Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04855266 | Iron Sucrose in Patients With Iron Deficiency and POTS | orthostatic hypotension | Sucrose (NPC130683) | NP level |
| NCT01842633 | Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache | pain | Caffeine (NPC256849) | NP level |
| NCT00903617 | Study to Test GSK256073 in Patients With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02388178 | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study | dental caries | Arginine (NPC226453) | NP level |
| NCT02140814 | Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT01902758 | Drug Combination on Exercise Performance at High Altitude | altitude sickness | Theophylline (NPC252603) | NP level |
| NCT02420314 | Pharmacological Ascorbate for Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01503060 | Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain | pain | Sucrose (NPC130683) | NP level |
| NCT00000461 | Harvard Atherosclerosis Reversibility Project (HARP) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00441870 | Study of EC0225 for the Treatment of Refractory or Metastatic Tumors | cancer | Folic Acid (NPC147983) | NP level |
| NCT03751592 | Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer | lung cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT03861416 | "Unifuzol®" in Patients With Peripheral Arterial Disease | peripheral arterial disease | Arginine (NPC226453) | NP level |
| NCT03253913 | Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial | lymphangioleiomyomatosis | Resveratrol (NPC161571) | NP level |
| NCT03761511 | Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia | Friedreich ataxia | Niacinamide (NPC306397) | NP level |
| NCT03015675 | IV Ascorbic Acid in Advanced Gastric Cancer | gastric cancer | Ascorbate (NPC187770) | NP level |
| NCT01984073 | Effects of Niacin On Fatty Acid Trapping | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04535427 | Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Arginine (NPC226453) | NP level |
| NCT00006136 | Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | Beta-thalassemia | Arginine (NPC226453) | NP level |
| NCT00626444 | Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL) | non-Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT02647086 | Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD) | atopic eczema | Caffeine (NPC256849) | NP level |
| NCT00485758 | Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT02174705 | Rotavirus vs. Sucrose for Vaccine Injection Pain | pain | Sucrose (NPC130683) | NP level |
| NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
| NCT00943124 | MK0524B Bioequivalence Study (0524B-070) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT03509662 | Vitamin C in Post-cardiac Arrest | cardiac arrest | Thiamine (NPC150950);Ascorbate (NPC187770) | NP level |
| NCT03510884 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00533611 | Effect of MK0524A on Flushing Caused by Niacin (0524A-056) | Flushing | Niacin (NPC167400) | NP level |
| NCT02541708 | IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in Tanzania | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT01191216 | 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT02013362 | Phase I/II Clinical Study of Pralatrexate in Japanese Patients With Relapsed or Refractory Peripheral T-cell Lymphoma | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT02261844 | Resveratrol and Human Hepatocyte Function in Cancer | liver cancer | Resveratrol (NPC161571) | NP level |
| NCT03205202 | Cataract and AMD in a Trial of a Multivitamin and Cocoa Extract | Cataract|Age Related Macular Degeneration | Theobroma Cacao | Plant level As plant Extract |
| NCT03797443 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01564381 | Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women | cardiovascular disease | Resveratrol (NPC161571) | NP level |
| NCT01140646 | Evaluation of SAMe for Hot Flashes | Hot flashes | Methionine (NPC152451) | NP level |
| NCT00806819 | Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00157521 | L-Arginine in Pre-Eclampsia | preeclampsia | Arginine (NPC226453) | NP level |
| NCT01677611 | Effects of Resveratrol in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
| NCT02114502 | Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma | multiple myeloma | Pyridoxine (NPC269919) | NP level |
| NCT02985671 | To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain. | Low back pain | Caffeine (NPC256849) | NP level |
| NCT00329498 | L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes | acute myeloid leukemia;myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT01116141 | A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04516681 | IV Ascorbic Acid in Peritoneal Metastatic Colorectal Cancer | colorectal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02030977 | The Effects of Resveratrol Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis | non-alcoholic fatty liver disease | Resveratrol (NPC161571) | NP level |
| NCT03509350 | Vitamin C, Thiamine, and Steroids in Sepsis | Sepsis | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT01550510 | Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | colorectal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT00024310 | Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors | neoplasm | Folic Acid (NPC147983) | NP level |
| NCT04478734 | Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease | Huntington disease | Thiamine (NPC150950) | NP level |
| NCT02168270 | Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma | anaplastic astrocytoma;anaplastic oligodendroglioma;gliosarcoma | Ascorbate (NPC187770) | NP level |
| NCT01766219 | CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery | cholangiocarcinoma;gallbladder neoplasm | Octanoic Acid (NPC301696) | NP level |
| NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Histidine (NPC237812);Tryptophan (NPC203468) | NP level |
| NCT01276704 | Prevention Strategy for Pre-Menopausal Women at High Risk for Development of Breast Cancer | breast cancer | (+)-Secoisolariciresinol (NPC85488) | NP level |
| NCT00000599 | Cholesterol-Lowering Atherosclerosis Study (CLAS) | carotid artery disease;cerebral atherosclerosis;Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00513617 | Effectiveness of Arginine as a Treatment for Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02606773 | "Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00406874 | Effect of Omega 3 Fats on Sperm Quality and Sexual Function | infertility | Folic Acid (NPC147983) | NP level |
| NCT05445232 | A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants | obesity | Caffeine (NPC256849) | NP level |
| NCT02066688 | Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT02314208 | Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 | Spastic paraplegia | Resveratrol (NPC161571) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Thiamine (NPC150950) | NP level |
| NCT00575848 | Study of the Effects of Glycine on Symptoms and Memory in Patients With Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT01850680 | Single Ascending Dose Study of Safety and Tolerability of Sarilumab and Methotrexate in Japanese Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT02728349 | Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
| NCT00289900 | Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT04554901 | The Effect of Cocoa on Platelet Function Profiles in Patients | Platelet Dysfunction | Theobroma Cacao | Plant level As single plant |
| NCT01054508 | Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02225093 | A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer | prostate cancer | Caffeine (NPC256849) | NP level |
| NCT02088502 | Theophylline, N-acetylcysteine, and Theophylline Plus N-acetylcysteine in Preventing Contrast-induced Nephropathy | kidney disease | Theophylline (NPC252603) | NP level |
| NCT01243242 | Clinical Efficacy & Safety, of Metadoxine (MG01CI) Extended Release in Attention-Deficit Hyperactivity Disorder (ADHD) | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT05009355 | The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT02523274 | Resveratrol and Exercise to Treat Functional Limitations in Late Life | aging | Resveratrol (NPC161571) | NP level |
| NCT00276263 | Sarcosine Preventive Therapy for Individuals At High Risk for Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT00536510 | Effect of MK0524A on Cholesterol Levels (0524A-048) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00241631 | Enhancement of in-Vitro GC Function in Patients With COPD | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT03493178 | Glutathione in Mild Cognitive Impairment | Cognitive impairment | Glycine (NPC126681) | NP level |
| NCT00500045 | Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT02701127 | Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury | Acute kidney injury | Niacinamide (NPC306397) | NP level |
| NCT02336633 | Resveratrol and Huntington Disease | Huntington disease | Resveratrol (NPC161571) | NP level |
| NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
| NCT00033722 | Lometrexol Plus Folic Acid in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT02947750 | Neurovascular Transduction During Exercise in Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00995085 | Efficacy Study of Metadoxine SR Formulation in Attention Deficit Hyperactivity Disorder (ADHD) Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract;macular degeneration | Ascorbate (NPC187770);Beta Carotene (NPC17810) | NP level |
| NCT00114400 | BVAIT: B-Vitamin Atherosclerosis Intervention Trial | atherosclerosis | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT00664287 | Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04844528 | Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC) | chronic lymphocytic leukemia | Niacinamide (NPC306397) | NP level |
| NCT00652431 | Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01589809 | Effect of Nicotinamide in Friedreich's Ataxia | neurodegenerative disease | Niacinamide (NPC306397) | NP level |
| NCT01504854 | Resveratrol for Alzheimer's Disease | Alzheimer disease | Resveratrol (NPC161571) | NP level |
| NCT03956056 | Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy | pancreatic carcinoma | Lysine (NPC112890) | NP level |
| NCT00120289 | Niacin Plus Statin to Prevent Vascular Events | stroke;atherosclerosis;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT00325572 | Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism | autism | Ascorbate (NPC187770) | NP level |
| NCT02516670 | Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer | metastatic prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT01011699 | Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT01419067 | A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection | Craniopharyngioma | Methionine (NPC152451) | NP level |
| NCT00147368 | Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT03066115 | Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation | hypoxia | Ascorbate (NPC187770) | NP level |
| NCT05289908 | Intrathecal Pemetrexed for Leptomeningeal Metastasis | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT02067975 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | schizophrenia | Tryptophan (NPC203468) | NP level |
| NCT04279535 | Topical Vitamin C for Treatment of Basal Cell Cancer | basal cell carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03022838 | The Effects of Caffeine Withdrawal on Migraine | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT02189772 | Safety and Tolerability Study of Metadoxine Extended Release (MDX) (Previously Known as MG01CI) in PI-ADHD Adolescent Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT01266018 | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Arginine (NPC226453) | NP level |
| NCT03745963 | The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU | pain | Sucrose (NPC130683) | NP level |
| NCT00692510 | Drug Interaction Study Between AZD3480 and Cytochrome P450 | Alzheimer disease | Caffeine (NPC256849) | NP level |
| NCT05042024 | Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | periodontitis | Arginine (NPC226453) | NP level |
| NCT01295450 | Study to Evaluate the Efficacy and Tolerability of Apevinat BC Compared to Vitamin Complex | Anorexia | Ascorbate (NPC187770) | NP level |
| NCT03580122 | The Effect of Arginine on Classic Galactosemia | classic galactosemia | Arginine (NPC226453) | NP level |
| NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
| NCT02083575 | Role of Vitamin C to Augment Iron Chelation With DFP or DFX | beta-thalassemia major | Ascorbate (NPC187770) | NP level |
| NCT01426438 | Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate | HIV-1 infection | Niacin (NPC167400) | NP level |
| NCT05457959 | Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant | glioma | Lysine (NPC112890) | NP level |
| NCT01686646 | Effects of Two Doses of a Common Cold Treatment on Alertness | common cold | Caffeine (NPC256849) | NP level |
| NCT04359823 | DSAP Treatment Comparison | porokeratosis | Cholesterol (NPC28657) | NP level |
| NCT02427581 | Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy | triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT00266227 | A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02773147 | Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine | HIV infection | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT03933163 | Micronised Resveratrol as a Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
| NCT00376584 | Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) | Disorder of lipid metabolism;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00218946 | Nasogastric Tube in Premature Babies - Pain and Treatment | premature birth | Sucrose (NPC130683) | NP level |
| NCT00298272 | Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04337879 | A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | colorectal cancer | Folic Acid (NPC147983) | NP level |
| NCT01900431 | Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis | uveitis | Folic Acid (NPC147983) | NP level |
| NCT01462370 | Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1) | Dysmenorrhea | Caffeine (NPC256849) | NP level |
| NCT01842139 | Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission | acute myeloid leukemia | Lysine (NPC112890) | NP level |
| NCT00133419 | Micronutrients and Enteric Infections in African Children | infection | Retinol (NPC55412) | NP level |
| NCT04928495 | Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02793648 | Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly. | depressive disorder | Ascorbate (NPC187770) | NP level |
| NCT02791906 | Targeting Central Pulsatile Hemodynamics in Chronic Kidney Disease | chronic kidney disease | Ascorbate (NPC187770) | NP level |
| NCT00056433 | Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02311088 | Trial of Caffeine to Alleviate Dyspnea Related to Ticagrelor | Dyspnea | Caffeine (NPC256849) | NP level |
| NCT02393378 | Namilumab vs Adalimumab in Participants With Moderate to Severe Early Rheumatoid Arthritis Inadequately Responding to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00726726 | Drug Interaction Study With a Potential Alzheimer's Disease Compound | Alzheimer disease | Caffeine (NPC256849) | NP level |
| NCT04449198 | Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1 | type 1 diabetes mellitus | Resveratrol (NPC161571) | NP level |
| NCT03097211 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT01603446 | L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome | MELAS | Arginine (NPC226453) | NP level |
| NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Ascorbate (NPC187770) | NP level |
| NCT00630877 | Evaluation of a Flushing ASsessment Tool (FAST) in Subjects Receiving Niacin Extended-release Plus Aspirin | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00269217 | Lipid Efficacy Study (0524B-022)(COMPLETED) | Combined hyperlipidemia;Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00170404 | TB Nutrition, Immunology and Epidemiology | tuberculosis | Niacin (NPC167400);Retinol (NPC55412);Folic Acid (NPC147983) | NP level |
| NCT00513110 | A Possible Therapeutic Role for Adenosine During Inflammation | serum lipopolysaccharide activity | Caffeine (NPC256849) | NP level |
| NCT01118624 | Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer | breast carcinoma | Folic Acid (NPC147983) | NP level |
| NCT02516085 | Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT01368328 | Effect of the Chromium Nicotinate on Type 2 Diabetes | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT02219906 | Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation | metabolic syndrome | Resveratrol (NPC161571) | NP level |
| NCT00495092 | Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients | cocaine dependence | Caffeine (NPC256849) | NP level |
| NCT01875159 | Effects of Caffeine on Intermittent Hypoxia in Infants Born Preterm | hypoxia | Caffeine (NPC256849) | NP level |
| NCT01107730 | Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT02974114 | Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain | pain | Caffeine (NPC256849) | NP level |
| NCT03508726 | High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas | soft tissue sarcoma | Ascorbate (NPC187770) | NP level |
| NCT00085345 | Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01517399 | Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects | neoplasm | Caffeine (NPC256849) | NP level |
| NCT02876887 | Cocoa to Improve Walking Performance in Peripheral Artery Disease | Peripheral Artery Disease | Theobroma Cacao | Plant level As single plant |
| NCT04334512 | A Study of Quintuple Therapy to Treat COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01080352 | Vitamin C as an Anti-cancer Drug | prostate adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT03166254 | Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer | non-small cell lung carcinoma | Lysine (NPC112890) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction | Folic Acid (NPC147983);Ascorbate (NPC187770);Pyridoxine (NPC269919);Beta Carotene (NPC17810) | NP level |
| NCT04989049 | Therapeutic Effect of Folic Acid in Healing of Oral Ulcers | Oral ulcer | Folic Acid (NPC147983) | NP level |
| NCT01083329 | Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects | obesity | Niacin (NPC167400) | NP level |
| NCT05210504 | Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3 | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT00300365 | Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL | metabolic syndrome | Niacin (NPC167400) | NP level |
| NCT04055818 | A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease | sickle cell anemia | Niacinamide (NPC306397) | NP level |
| NCT01407432 | Impact of Folates in the Care of the Male Infertility | male infertility | Folic Acid (NPC147983) | NP level |
| NCT01010581 | SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02702492 | PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA) | non-Hodgkins lymphoma | Niacin (NPC167400) | NP level |
| NCT01071525 | The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00268749 | Glycine Treatment of Prodromal Symptoms | schizophrenia | Glycine (NPC126681) | NP level |
| NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983);Ascorbate (NPC187770) | NP level |
| NCT02318446 | Efficacy Study of Folic Acid Supplementation in Adolescent Epileptics | epilepsy | Folic Acid (NPC147983) | NP level |
| NCT00211562 | Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids | schizophrenia | Ascorbate (NPC187770) | NP level |
| NCT00184054 | Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous Leukemia | acute myeloid leukemia | Ascorbate (NPC187770) | NP level |
| NCT03606967 | Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT04357782 | Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation | hypoxia;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00433576 | Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery | colorectal adenocarcinoma;malignant colon neoplasm;rectum cancer | Resveratrol (NPC161571) | NP level |
| NCT00300352 | Effect of Folic Acid Treatment in Coronary Artery Disease | coronary artery disease | Folic Acid (NPC147983) | NP level |
| NCT04570085 | Effect of CAFfeine on Cognition in Alzheimer's Disease | Alzheimer disease | Caffeine (NPC256849) | NP level |
| NCT02520752 | A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors | neoplasm | Caffeine (NPC256849) | NP level |
| NCT01238471 | Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study | retinopathy of prematurity | Sucrose (NPC130683) | NP level |
| NCT02093026 | Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00003684 | Theophylline in Treating Cancer Patients With Shortness of Breath | respiratory failure | Theophylline (NPC252603) | NP level |
| NCT00475176 | S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C | chronic hepatitis C virus infection | Methionine (NPC152451) | NP level |
| NCT00405665 | The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis | cystic fibrosis | Arginine (NPC226453) | NP level |
| NCT04240821 | Theophylline for Treatment of Pseudohypoparathyroidism | Albright hereditary osteodystrophy;pseudohypoparathyroidism type 1A | Theophylline (NPC252603) | NP level |
| NCT00763633 | B6 Treatment for Nausea and Vomiting in Pregnancy | Nausea and vomiting | Pyridoxine (NPC269919) | NP level |
| NCT00000553 | HDL-Atherosclerosis Treatment Study (HATS) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00953134 | Periconceptional Iron Supplementation in Rural Bangladesh | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT00378833 | Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00672360 | Folate Rechallenge | autism | Folic Acid (NPC147983) | NP level |
| NCT00269204 | Lipid Efficacy/Tolerability Study (0524A-020) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00223717 | Treatment of Supine Hypertension in Autonomic Failure | hypertension | Arginine (NPC226453) | NP level |
| NCT01871766 | Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy | rhabdomyosarcoma | Methionine (NPC152451) | NP level |
| NCT01356966 | Exercise Intolerance in Renal Failure | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00803530 | Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes | myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT01183065 | Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) | head and neck malignant neoplasia | Folic Acid (NPC147983) | NP level |
| NCT00280683 | Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma | asthma | Arginine (NPC226453) | NP level |
| NCT03172325 | Study to Demonstrate Non-Inferior Efficacy and Safety of CinnoRA® Versus Humira® for Treatment of Active RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03419364 | Study of Nicotinamide in Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT04347889 | Preventing COVID-19 in Healthcare Workers With HCQ: A RCT | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00202280 | Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication | psychosis | Pyridoxine (NPC269919);Folic Acid (NPC147983) | NP level |
| NCT02472626 | 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia | acute myeloid leukemia | Octanoic Acid (NPC301696) | NP level |
| NCT04268849 | Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT03121677 | Personalized Tumor Vaccine Strategy and PD-1 Blockade in Patients With Follicular Lymphoma | follicular lymphoma | Lysine (NPC112890) | NP level |
| NCT03091868 | Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT02183688 | Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT03516903 | Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI | myocardial infarction | Folic Acid (NPC147983) | NP level |
| NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02735707 | Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia | COVID-19;influenza;pneumonia | Ascorbate (NPC187770) | NP level |
| NCT01066728 | CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity | Apnea | Theophylline (NPC252603) | NP level |
| NCT03685773 | The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01468038 | A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food | Sleep Disorder | L-Glutamate (NPC137958) | NP level |
| NCT00203476 | A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01985685 | The Effect of Thiamine vs. Placebo on VO2 in Critical Illness | respiratory failure | Thiamine (NPC150950) | NP level |
| NCT03260166 | Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus | cutaneous lupus erythematosus;systemic lupus erythematosus | Niacinamide (NPC306397) | NP level |
| NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
| NCT03602235 | High Dose Ascorbic Acid for Plasma Cell Disorders | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02125786 | A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma | ependymoma | Methionine (NPC152451) | NP level |
| NCT00136188 | Nitric Oxide (NO) Activity and Diabetic Nephropathy | diabetic nephropathy | Folic Acid (NPC147983) | NP level |
| NCT01017939 | A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer | prostate carcinoma | Theophylline (NPC252603) | NP level |
| NCT04715022 | Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) | hypertension | Ascorbate (NPC187770) | NP level |
| NCT01364805 | New Treatment Option for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00402883 | Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT01720316 | Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders | bipolar disorder | Glycine (NPC126681) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | Sepsis | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT03581773 | Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy | mucositis | Folic Acid (NPC147983) | NP level |
| NCT00917826 | Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | lymphoma | Arginine (NPC226453) | NP level |
| NCT00691210 | Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies | Hodgkins lymphoma;non-Hodgkins lymphoma | Niacinamide (NPC306397) | NP level |
| NCT00965653 | A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03799094 | Vitamin C and Tyrosine Kinase Inhibitor in Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02780505 | Assessment of the Effect of Vitamin C on Anemia in Patients With Continuous Ambulatory Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT01070810 | Thiamine as a Metabolic Resuscitator in Septic Shock | septic shock | Thiamine (NPC150950) | NP level |
| NCT05452772 | 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder | nicotine dependence | Niacin (NPC167400) | NP level |
| NCT00000578 | NHLBI/NICHD Collaborative Studies of Asthma in Pregnancy | asthma | Theophylline (NPC252603) | NP level |
| NCT01902381 | CPI-613 in Treating Patients With Myelodysplastic Syndromes Who Failed Previous Therapy | myelodysplastic syndrome | Octanoic Acid (NPC301696) | NP level |
| NCT01596647 | Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors | neoplasm | Caffeine (NPC256849) | NP level |
| NCT02048215 | Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity | obesity | Caffeine (NPC256849) | NP level |
| NCT00222235 | Adjunctive Treatment for Decreasing Symptoms of Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT04404387 | Lessening Organ Dysfunction With VITamin C in Septic ARDS | acute respiratory distress syndrome | Ascorbate (NPC187770) | NP level |
| NCT03626298 | Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia | acne | Niacinamide (NPC306397) | NP level |
| NCT04553666 | Reducing Frailty for Older Cancer Survivors Using Supplements | inflammation | Ascorbate (NPC187770) | NP level |
| NCT00299130 | A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03800667 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT03697239 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT01880866 | (-)-Epicatechin and Pulmonary Arterial Hypertension | pulmonary arterial hypertension | (-)-Epicatechin (NPC126029) | NP level |
| NCT00756418 | Montelukast Post-marketing Comparative Study With Theophyline Added to Inhaled Corticosteroid (0476-396) | asthma | Theophylline (NPC252603) | NP level |
| NCT02424201 | Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja. | postpartum hemorrhage | Ascorbate (NPC187770) | NP level |
| NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
| NCT00067899 | Oxidative Stress and Vitamin E Requirements | nicotine dependence | Ascorbate (NPC187770) | NP level |
| NCT02245204 | Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers | cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT00966836 | Prevention of Transplant Atherosclerosis With Everolimus and Anti-cytomegalovirus Therapy | cytomegalovirus infection | Phenol (NPC100980) | NP level |
| NCT01569919 | A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma | mesothelioma | Folic Acid (NPC147983) | NP level |
| NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Resveratrol (NPC161571);Quercetin (NPC20791) | NP level |
| NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Niacinamide (NPC306397);Methionine (NPC152451) | NP level |
| NCT02862977 | Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment | pain | Caffeine (NPC256849) | NP level |
| NCT04750902 | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children | dental caries | Arginine (NPC226453) | NP level |
| NCT01752491 | A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT00397917 | Oral Cleft Prevention Program | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT03188445 | Intravenous Iron Isomaltoside Versus Oral Iron Supplementation for Treatment of Iron Deficiency in Pregnancy. | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT04783792 | The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention | osteoarthritis | Ascorbate (NPC187770) | NP level |
| NCT00271817 | To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00284427 | Safety of Antioxidants During GYN Cancer Care | cervical cancer;ovarian cancer | Ascorbate (NPC187770) | NP level |
| NCT01949116 | Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications | HIV infection | Folic Acid (NPC147983) | NP level |
| NCT03990766 | Smell Changes & Efficacy of Nasal Theophylline | viral disease | Theophylline (NPC252603) | NP level |
| NCT04616248 | In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT01321151 | Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers | concussion | Resveratrol (NPC161571) | NP level |
| NCT00034463 | ALIMTA (Pemetrexed) in Patients With Locally Advanced or Metastatic Cancer | cancer | Folic Acid (NPC147983) | NP level |
| NCT02930343 | Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04504045 | Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Caffeine (NPC256849) | NP level |
| NCT00769132 | A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00654667 | Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome | insulin resistance | Resveratrol (NPC161571) | NP level |
| NCT04898023 | Zinc and Green Tea Extract for Community Respiratory Viral Infections | viral disease | Ascorbate (NPC187770) | NP level |
| NCT00252863 | DESOLO - SiT Peri-Launch: A Comparison of Symbicort Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma in Adults | asthma | Theophylline (NPC252603) | NP level |
| NCT00112879 | Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT03540758 | Regulation of Endogenous Glucose Production by Central KATP Channels | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT02863575 | A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine | pain | Caffeine (NPC256849) | NP level |
| NCT02905591 | A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Arginine (NPC226453) | NP level |
| NCT02109614 | Early Aortic Valve Lipoprotein(a) Lowering Trial | aortic stenosis | Niacin (NPC167400) | NP level |
| NCT02136342 | Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer | cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Resveratrol (NPC161571);Quercetin (NPC20791) | NP level |
| NCT03679780 | The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT00096330 | Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT04551170 | Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old | Albright hereditary osteodystrophy;pseudohypoparathyroidism type 1A | Theophylline (NPC252603) | NP level |
| NCT02961816 | Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT02549924 | Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
| NCT00606502 | Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT02447874 | Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT03334409 | Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery | clear cell renal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02772601 | This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis | psoriasis | Caffeine (NPC256849) | NP level |
| NCT00029679 | Borage Oil and Ginkgo Biloba (EGb 761) in Asthma | asthma | Linoleic Acid (NPC85813) | NP level |
| NCT04764383 | Histaminergic Basis of Fatigue in Multiple Sclerosis | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT01319734 | Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT02433925 | Resveratrol's Effects on Inflammation and Oxidative Stress in Chronic Kidney Disease | chronic kidney disease | Resveratrol (NPC161571) | NP level |
| NCT03094156 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT00807807 | Evaluating the Effects of Folic Acid Supplementation in Older Adults: The Folic Acid Supplementation Trial (The FAST Study) | heart disease | Folic Acid (NPC147983) | NP level |
| NCT02602483 | Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). | temporomandibular joint disorder | Ascorbate (NPC187770) | NP level |
| NCT04246762 | Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4 | rheumatoid arthritis | Caffeine (NPC256849) | NP level |
| NCT03592693 | Vitamin C, Hydrocortisone and Thiamine for Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT03162562 | The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer | ovarian carcinoma | Lysine (NPC112890) | NP level |
| NCT00316472 | The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT02106650 | Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT02786823 | Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT02086864 | A Placebo Controlled Study of Homeopathic Treatment of Children and Youth With ADHD | attention deficit hyperactivity disorder | Sucrose (NPC130683) | NP level |
| NCT01050621 | Trial of Chemotherapy Plus Intravenous Vitamin C in Patients With Advanced Cancer for Whom Chemotherapy Alone is Only Marginally Effective | cancer | Ascorbate (NPC187770) | NP level |
| NCT02908581 | Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis | heavy metal poisoning | Folic Acid (NPC147983) | NP level |
| NCT00154700 | Twice Weekly TP-HDFL for Recurrent or Metastatic Esophageal Cancer | esophageal cancer | Folic Acid (NPC147983) | NP level |
| NCT02206425 | Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02878265 | The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children | malaria | Retinol (NPC55412) | NP level |
| NCT02740712 | Pharmacokinetic Drug-Drug Interaction Study of Rucaparib | neoplasm | Caffeine (NPC256849) | NP level |
| NCT01417481 | Effect of Glycine in Cystic Fibrosis | cystic fibrosis | Glycine (NPC126681) | NP level |
| NCT00469209 | Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00338221 | Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT05096663 | Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01217814 | Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00973609 | Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC) | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT01525628 | Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients | chronic hepatitis C virus infection | Caffeine (NPC256849) | NP level |
| NCT01953536 | Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004) | breast neoplasm | Folic Acid (NPC147983) | NP level |
| NCT01248468 | Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT02479451 | Helping Olfaction and Nutrition On Renal Replacement | chronic kidney disease | Theophylline (NPC252603) | NP level |
| NCT01436266 | Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion | hemorrhage | Folic Acid (NPC147983) | NP level |
| NCT00119496 | Rosiglitazone Versus Theophylline in Asthmatic Smokers | asthma | Theophylline (NPC252603) | NP level |
| NCT01345474 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT00609518 | A Study for Patients With Non-Squamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT02678234 | An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT01190995 | Role of Repeated Painful Procedures in Preterm Neonates on Short Term Neurobehavioural Outcome | pain | Sucrose (NPC130683) | NP level |
| NCT02582996 | Cefalium® Compared to Tylenol® in the Treatment of Migraine Attacks | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT03533556 | Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder | attention deficit hyperactivity disorder | Caffeine (NPC256849) | NP level |
| NCT01071291 | Effects of Niaspan™ on High-density Lipoprotein (HDL) in Healthy Male Subjects (0000-069) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00271635 | Ascorbic Acid Treatment in CMT1A Trial (AATIC) | Charcot-Marie-Tooth disease | Ascorbate (NPC187770) | NP level |
| NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
| NCT00128557 | Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh | vitamin A deficiency | Retinol (NPC55412) | NP level |
| NCT00384293 | Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01587963 | High Dose Vitamin C in the Critically Ill Patient | Shock | Ascorbate (NPC187770) | NP level |
| NCT00781196 | Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth | gingival overgrowth | Folic Acid (NPC147983) | NP level |
| NCT03093389 | Tolerability and Steady-state Pharmacokinetics of BIA 6-512 | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT02541045 | Clinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepatitis | non-alcoholic fatty liver disease | Pyridoxine (NPC269919) | NP level |
| NCT01842399 | Resveratrol and Cardiovascular Health in the Elderly | hypertension | Resveratrol (NPC161571) | NP level |
| NCT03148236 | Vitamin C in Atrial Fibrillation Ablation | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT00533312 | MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00951158 | A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors | neoplasm | Linoleic Acid (NPC85813) | NP level |
| NCT01080677 | Caffeine/Propranolol Intervention for Acute Migraine | migraine disorder | Caffeine (NPC256849) | NP level |
| NCT01190735 | Caffeine for Motor Manifestations of Parkinson's Disease | Parkinson disease | Caffeine (NPC256849) | NP level |
| NCT00957359 | Psilocybin Cancer Anxiety Study | cancer | Niacin (NPC167400) | NP level |
| NCT02467504 | Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01275170 | A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005) | infectious disease | Caffeine (NPC256849) | NP level |
| NCT04364750 | Biomarkers of Diet-microbiota Interactions in Irritable Bowel Syndrome | irritable bowel syndrome | Histidine (NPC237812) | NP level |
| NCT01754662 | Effects of Combining Cocoa and Soy in Type 2 Diabetes | Type 2 Diabetes|Dietary Intervention | Theobroma Cacao | Plant level As single plant |
| NCT02744820 | Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT00377975 | "Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat | obesity | Caffeine (NPC256849) | NP level |
| NCT01061736 | Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00033436 | Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer | urinary bladder cancer | Niacinamide (NPC306397) | NP level |
| NCT03095092 | Effect of Food on BIA 6-512 (Trans-resveratrol) | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT03743636 | Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease | peripheral arterial disease | Resveratrol (NPC161571) | NP level |
| NCT00004758 | Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment | epilepsy | Pyridoxine (NPC269919) | NP level |
| NCT00070434 | S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT03187496 | Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers. | non-alcoholic steatohepatitis | Caffeine (NPC256849) | NP level |
| NCT01983969 | Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma | cancer;lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT04301336 | Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT03175341 | Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer | breast cancer | Ascorbate (NPC187770) | NP level |
| NCT00227682 | Arsenic Trioxide, Thalidomide, Dexamethasone, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00573313 | Effects of SAMe in Patients With Alcoholic Liver Disease | liver disease | Methionine (NPC152451) | NP level |
| NCT01703104 | The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT00000512 | Familial Atherosclerosis Treatment Study | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT03088345 | Early Use of Vasopressin in Post-Fontan Management | congenital heart disease | Arginine (NPC226453) | NP level |
| NCT04446104 | A Preventive Treatment for Migrant Workers at High-risk of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03887169 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | pulmonary alveolar proteinosis | Folic Acid (NPC147983);Pyridoxine (NPC269919);Methionine (NPC152451);Ascorbate (NPC187770) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Ascorbate (NPC187770) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Retinol (NPC55412);Folic Acid (NPC147983);Niacin (NPC167400);Ascorbate (NPC187770);Pyridoxine (NPC269919) | NP level |
| NCT04344184 | SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI) | acute lung injury;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03522922 | Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring | acne | Ascorbate (NPC187770) | NP level |
| NCT02297399 | Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT02655614 | A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis | amyotrophic lateral sclerosis | Caffeine (NPC256849) | NP level |
| NCT00345150 | Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls | hypertension | Arginine (NPC226453) | NP level |
| NCT00204932 | Effects of CLA Supplements on Body Weight and Fat Oxidation | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT00223691 | Treatment of Orthostatic Hypotension in Autonomic Failure | orthostatic hypotension | Caffeine (NPC256849) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | septic shock | Thiamine (NPC150950);Ascorbate (NPC187770) | NP level |
| NCT00098969 | UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants | neoplasm | Resveratrol (NPC161571) | NP level |
| NCT02463409 | Theophylline as a Treatment for Children With Pseudohypoparathyroidism Type 1a (Albright Hereditary Osteodystrophy) | Albright hereditary osteodystrophy;pseudohypoparathyroidism type 1A | Theophylline (NPC252603) | NP level |
| NCT00965068 | Cholesterol in ASD: Characterization and Treatment | Asperger syndrome;autism | Cholesterol (NPC28657) | NP level |
| NCT03970798 | A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin | Parkinson disease | Caffeine (NPC256849) | NP level |
| NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
| NCT02416739 | Anticancer Activity of Nicotinamide on Lung Cancer | non-small cell lung carcinoma | Niacinamide (NPC306397) | NP level |
| NCT01599871 | Low-dose Theophylline as Anti-inflammatory Enhancer in Severe Chronic Obstructive Pulmonary Disease | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT00634998 | Vitamin C Supplementation as a Preventive Treatment of Diabetic Peripheral Neuropathy | diabetic neuropathy | Ascorbate (NPC187770) | NP level |
| NCT01711359 | A Study in Participants With Moderate to Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00961636 | A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00855257 | Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome | acute coronary syndrome | Niacin (NPC167400) | NP level |
| NCT03828929 | Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT03224572 | The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT02795299 | Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03131973 | Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin | rheumatoid arthritis | Caffeine (NPC256849) | NP level |
| NCT00443170 | A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects | anemia (phenotype) | Caffeine (NPC256849) | NP level |
| NCT02186158 | Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized. | pneumonia | Ascorbate (NPC187770) | NP level |
| NCT00986609 | MUC1 Vaccine for Triple-negative Breast Cancer | inflammatory breast carcinoma;triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT02699099 | Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. | malaria | Retinol (NPC55412) | NP level |
| NCT01126229 | Resveratrol for Improved Performance in the Elderly | memory impairment | Resveratrol (NPC161571) | NP level |
| NCT01587261 | Vitamin C for Severe Thermal Injuries | injury | Ascorbate (NPC187770) | NP level |
| NCT01685281 | Study Comparing Two Doses of MG01CI and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00150722 | High-Density Lipoprotein (HDL) Modulation and Endothelial Function | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT02291458 | L-arginine and Brown Adipose Tissue | Glucose intolerance | Arginine (NPC226453) | NP level |
| NCT02323698 | Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury | Spinal cord injury | Caffeine (NPC256849) | NP level |
| NCT00825695 | Flavanol-Rich Cocoa and Cerebral Blood Flow | Hypertension|Diabetes | Theobroma Cacao | Plant level As single plant |
| NCT00633581 | Efficacy of Vitamin C Injection on Fatigue in Workers After Work | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT04649203 | Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy | diabetic neuropathy | Niacinamide (NPC306397) | NP level |
| NCT03872011 | Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock | septic shock | Ascorbate (NPC187770);Thiamine (NPC150950) | NP level |
| NCT02213094 | Phase I Study of Nicotinamide for Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT02258074 | The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT03266965 | Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT00484510 | High Dose Ascorbic Acid Treatment of CMT1A | Charcot-Marie-Tooth disease type 1A | Ascorbate (NPC187770) | NP level |
| NCT01583647 | A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01908452 | Pyridoxal Kinase Activity in Tardive Dyskinesia | movement disorder | Pyridoxine (NPC269919) | NP level |
| NCT01738178 | Caffeine as a Therapy for Parkinson's Disease | Parkinson disease | Caffeine (NPC256849) | NP level |
| NCT00580931 | Safety Study of Nicotinamide to Treat Alzheimer's Disease | Alzheimer disease | Niacinamide (NPC306397) | NP level |
| NCT01468948 | Octanoic Acid for Essential Tremor | essential tremor | Octanoic Acid (NPC301696) | NP level |
| NCT01670955 | The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT02903355 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT01172405 | Efficacy and Safety Study to Compare Ibuprofen + Caffeine With Ibuprofen Alone in the Treatment of Headache | Headache | Caffeine (NPC256849) | NP level |
| NCT04542993 | Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy | COVID-19;severe acute respiratory syndrome | Resveratrol (NPC161571) | NP level |
| NCT04670081 | Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression | depressive disorder | Niacinamide (NPC306397) | NP level |
| NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
| NCT00804843 | Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED) | carotid atherosclerosis | Niacin (NPC167400) | NP level |
| NCT03640949 | Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest | sudden cardiac arrest | Arginine (NPC226453) | NP level |
| NCT00175812 | Differentiation Induction in Acute Myelogenous Leukemia | acute myeloid leukemia | Theophylline (NPC252603) | NP level |
| NCT03268902 | Early Life Interventions for Childhood Growth and Development In Tanzania | malnutrition | Niacinamide (NPC306397) | NP level |
| NCT00459420 | Caffeine for Excessive Daytime Somnolence in Parkinson's Disease | Parkinson disease | Caffeine (NPC256849) | NP level |
| NCT03410030 | Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT00471952 | Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache | migraine with aura;migraine without aura | Caffeine (NPC256849) | NP level |
| NCT04046094 | Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients | urinary bladder cancer | Ascorbate (NPC187770) | NP level |
| NCT02756117 | The Effect of Acute Lysine Administration on α-aminoadipic Acid | prediabetes syndrome | Lysine (NPC112890) | NP level |
| NCT00944645 | MK0524A Bioequivalence Study (0524A-059) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT03758014 | Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Grade IV GBM Patients | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
| NCT00052715 | Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT03082001 | Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies | pain | Sucrose (NPC130683) | NP level |
| NCT03769285 | Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial | basal cell carcinoma;squamous cell carcinoma | Niacinamide (NPC306397) | NP level |
| NCT04363216 | Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00452829 | Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study) | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT00071266 | The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT00220532 | Folate and Protection Against Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT02440061 | Ghrelin and Beta Cell Function in Diabetes | type 2 diabetes mellitus | Arginine (NPC226453) | NP level |
| NCT00607945 | Dietary Fatty Acids as Complementary Therapy in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Linoleic Acid (NPC85813) | NP level |
| NCT01115504 | Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy | heart failure | Thiamine (NPC150950) | NP level |
| NCT03272594 | The Influence of Breastfeeding on Cortical Activity During Procedures | pain | Sucrose (NPC130683) | NP level |
| NCT04309877 | Theophylline for Depression Study | depressive disorder | Theophylline (NPC252603) | NP level |
| NCT02762838 | Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00152893 | To Determine if Chromium Nicotinate Supplementation Will Improve Insulin Resistance in HIV Patients With Metabolic Abnormalities | HIV infection | Niacin (NPC167400) | NP level |
| NCT02563327 | Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT00432887 | Experimental Studies of the Effects of Caffeine on Glucose Regulation | type 2 diabetes mellitus | Caffeine (NPC256849) | NP level |
| NCT01490944 | Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT02109315 | Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes. | type 1 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT01321034 | Effect of Niacin in the Lipoprotein (a) Concentration | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00000555 | Women's Angiographic Vitamin and Estrogen Trial (WAVE) | menopause;Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT00299104 | A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02017249 | Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme | glioblastoma multiforme | Arginine (NPC226453) | NP level |
| NCT00000482 | Coronary Drug Project | Myocardial Ischemia;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT02114892 | Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Resveratrol (NPC161571) | NP level |
| NCT01324115 | NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors | neoplasm | Arginine (NPC226453) | NP level |
| NCT01796678 | Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial | pain | Arginine (NPC226453) | NP level |
| NCT02340520 | Enhancement of Corticosteroid Efficacy in COPD | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT00536237 | MK0524A Phase IIb Study (0524A-011)(COMPLETED) | Flushing | Niacin (NPC167400) | NP level |
| NCT02833350 | Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00000372 | Glycine and D-Cycloserine in Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT03556592 | Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4 | atopic eczema | Caffeine (NPC256849) | NP level |
| NCT02730364 | An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT02612259 | A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity | obesity | Tryptophan (NPC203468) | NP level |
| NCT05284656 | Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00000324 | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 | cocaine dependence | Tryptophan (NPC203468) | NP level |
| NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT03090048 | Vitamin A and Azithromycin for Acne Vulgaris | acne | Retinol (NPC55412) | NP level |
| NCT00694564 | Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children | Abdominal pain | Methionine (NPC152451) | NP level |
| NCT01388764 | Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT01936831 | High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB) | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT04867252 | Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome | polycystic ovary syndrome | Resveratrol (NPC161571) | NP level |
| NCT00470522 | Study of Methotrexate in Lupus Erythematosus | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT00003808 | Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic Leukemia | leukemia | Theophylline (NPC252603) | NP level |
| NCT02484391 | CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma | Granulocytic Sarcoma | Octanoic Acid (NPC301696) | NP level |
| NCT01783431 | Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells | melanoma | Lysine (NPC112890) | NP level |
| NCT05363917 | Natrunix Versus Methotrexate in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00437632 | Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809 | substance dependence | Caffeine (NPC256849) | NP level |
| NCT01696214 | A Pilot Study to Determine the Feasibility and Utility of Implementing of the Full Scale TOM Trial | asthma | Theophylline (NPC252603) | NP level |
| NCT00703196 | Folic Acid Clinical Trial for the Prevention of Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT01057615 | Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma | asthma | Ascorbate (NPC187770) | NP level |
| NCT05378919 | Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer | rectum cancer | Folic Acid (NPC147983) | NP level |
| NCT00441207 | Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors | cancer | Ascorbate (NPC187770) | NP level |
| NCT03864042 | Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors | metastatic melanoma | Caffeine (NPC256849) | NP level |
| NCT01416480 | Clinical Trial to Evaluate the Safety and Efficacy of "Theobromine Capsule" as an Antitussive in Acute Cougher | bronchial disease | Theobromine (NPC119133) | NP level |
| NCT01931787 | CPI-613 in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Octanoic Acid (NPC301696) | NP level |
| NCT00062556 | Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT05470998 | L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00243412 | A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00009841 | Gene Therapy in Treating Patients With Advanced Head and Neck Cancer | head and neck malignant neoplasia | Cholesterol (NPC28657) | NP level |
| NCT00345605 | Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder | argininosuccinic aciduria | Arginine (NPC226453) | NP level |
| NCT00262730 | Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT01201954 | Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning | pain | Sucrose (NPC130683) | NP level |
| NCT00616304 | Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT02107976 | Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00302289 | B181: Stimulation of Thermogenesis by Bio-Active Food Ingredients | obesity | Caffeine (NPC256849) | NP level |
| NCT02969681 | Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer | colorectal neoplasm | Ascorbate (NPC187770) | NP level |
| NCT04345705 | Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma | mesothelioma | Lysine (NPC112890) | NP level |
| NCT04261036 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT02409537 | Effects of Dietary Antioxidants to Prevent Cardiovascular Disease | Hypercholesterolemia | Resveratrol (NPC161571) | NP level |
| NCT03166228 | Hemodynamic Changes During Operative Hysteroscopy | hypertension | Glycine (NPC126681) | NP level |
| NCT00733993 | Caffeine and Cocaine | cocaine dependence | Caffeine (NPC256849) | NP level |
| NCT05501548 | Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer | prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT01502280 | Fluorescence-guided Surgery for Low- and High-grade Gliomas | glioma | Ascorbate (NPC187770) | NP level |
| NCT04870866 | NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia | Ataxia-telangiectasia | Niacinamide (NPC306397) | NP level |
| NCT00256334 | Resveratrol for Patients With Colon Cancer | malignant colon neoplasm | Resveratrol (NPC161571) | NP level |
| NCT02905799 | Resveratrol in Knee Osteoarthritis | osteoarthritis | Resveratrol (NPC161571) | NP level |
| NCT00299858 | Theophylline in Chronic Obstructive Pulmonary Disease | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT02225886 | Ascorbic Acid Administration in the Treatment of Anemia in Chronic Hemodialysed Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT03649633 | Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT00002650 | High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00848172 | Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor | essential tremor | Octanoic Acid (NPC301696) | NP level |
| NCT00861523 | Does Thiamine Help Vomiting and Nausea in Pregnancy? | hyperemesis gravidarum | Thiamine (NPC150950);Thiamine Hydrochloride (NPC189436) | NP level |
| NCT01920191 | Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma | neoplasm | Lysine (NPC112890) | NP level |
| NCT03223519 | COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS) | muscular disease | Ascorbate (NPC187770) | NP level |
| NCT03392623 | DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. | freckles | Niacinamide (NPC306397) | NP level |
| NCT00578305 | A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT05283954 | Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03418038 | Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or Clonal Cytopenia of Undetermined Significance | Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT03866174 | A Study of Psilocybin for Major Depressive Disorder (MDD) | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT00005107 | Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT01661764 | Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention | colorectal adenoma | Oleic Acid (NPC261831) | NP level |
| NCT03091543 | Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
| NCT00480207 | Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults | depressive disorder | Folic Acid (NPC147983) | NP level |
| NCT01799161 | Combination of gp96-Ig Vaccine, Theophylline and Oxygen for the Treatment of Patients With Advanced, Relapsed or Metastatic Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Theophylline (NPC252603) | NP level |
| NCT00098319 | Oral Cleft Prevention Trial in Brazil | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT02655913 | Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03964688 | Effect of Vitamin C in Autologous Stem Cell Transplantations | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Folic Acid (NPC147983);Pyridoxine (NPC269919);Beta Carotene (NPC17810) | NP level |
| NCT01864057 | Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants | beriberi | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT04401150 | Lessening Organ Dysfunction With VITamin C - COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01339884 | A Study of Resveratrol as Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
| NCT01263106 | A Study of LY2216684 and Theophylline in Healthy Subjects | major depressive disorder | Theophylline (NPC252603) | NP level |
| NCT00133406 | Long-term Impact and Intervention for Diarrhea in Brazil | diarrheal disease | Retinol (NPC55412);Glycine (NPC126681) | NP level |
| NCT02929888 | Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients | acute myocardial infarction | Lysine (NPC112890) | NP level |
| NCT00920413 | Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT02868151 | Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers | oral mucositis | Ascorbate (NPC187770) | NP level |
| NCT01276951 | Controlled Clinical Trial to Determine the Effective Dose of Cocoa in Lowering Blood Pressure | Hypertension | Theobroma Cacao | Plant level As single plant |
| NCT01368887 | Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis | psoriasis | Niacinamide (NPC306397) | NP level |
| NCT03984188 | Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD | chronic obstructive pulmonary disease | Theophylline (NPC252603) | NP level |
| NCT01042535 | Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer | male breast carcinoma | Tryptophan (NPC203468) | NP level |
| NCT02130440 | Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis | seasonal allergic rhinitis | Resveratrol (NPC161571) | NP level |
| NCT01057589 | A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer | upper aerodigestive tract neoplasm | Folic Acid (NPC147983) | NP level |
| NCT03359239 | Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer | urinary bladder cancer | Lysine (NPC112890) | NP level |
| NCT01976676 | Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion | habitual abortion | Folic Acid (NPC147983) | NP level |
| NCT03446625 | Resveratrol as a Preventive Treatment of OHSS | infertility | Resveratrol (NPC161571) | NP level |
| NCT00618995 | A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT00005658 | Glycine to Treat Psychotic Disorders in Children | schizophrenia | Glycine (NPC126681) | NP level |
| NCT04383639 | Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes | Type 2 Diabetes | Theobroma Cacao | Plant level As single plant |
| NCT03908333 | High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT03510715 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02621060 | Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance | abnormal glucose tolerance | Chlorogenic Acid (NPC302857) | NP level |
| NCT00631111 | Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain | pain | Ascorbate (NPC187770) | NP level |
| NCT03450707 | Thiamine as a Metabolic Resuscitator After Cardiac Arrest | cardiac arrest | Thiamine (NPC150950) | NP level |
| NCT03356483 | Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study. | obsessive-compulsive disorder | Niacin (NPC167400) | NP level |
| NCT02701673 | Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00134433 | Endothelial Modulation for Angiogenic Therapy | coronary artery disease | Arginine (NPC226453) | NP level |
| NCT00108589 | S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis | Hepatitis | Methionine (NPC152451) | NP level |
| NCT01293734 | Research on Traditional Chinese Medicine (TCM) Clinical Treatment of the Acute Episode of Bronchial Asthma. | asthma | Theophylline (NPC252603) | NP level |
| NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Arginine (NPC226453) | NP level |
| NCT00344916 | Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT00397657 | Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT01501942 | Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma | asthma | Glycine (NPC126681) | NP level |
| NCT01462318 | An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis | relapsing-remitting multiple sclerosis | Caffeine (NPC256849) | NP level |
| NCT01197040 | Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome | nephrotic syndrome | Phenol (NPC100980) | NP level |
| NCT03268733 | The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome | polycystic ovary syndrome | Folic Acid (NPC147983) | NP level |
| NCT02734147 | High Dose Intravenous Ascorbic Acid in Severe Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
| NCT00908791 | Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue | breast cancer | Linoleic Acid (NPC85813) | NP level |
| NCT02631668 | the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT02369822 | Trial of Vitamin C as Add on Therapy for Children With Idiopathic Epilepsy | epilepsy | Ascorbate (NPC187770) | NP level |
| NCT00949104 | Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates | pain | Sucrose (NPC130683) | NP level |
| NCT00482560 | Analgesic Effect of Breast Feeding vs Sucrose in Neonatal Screening | pain | Sucrose (NPC130683) | NP level |
| NCT01792310 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | glioma | Oleic Acid (NPC261831) | NP level |
| NCT00974714 | L-arginine Effects on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT03269318 | PRISTINE - Personalised Approach to Improve aSThma prescrIbing iN childrEn | asthma | Theophylline (NPC252603) | NP level |
| NCT00111891 | An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00520247 | Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism | hypertension | Folic Acid (NPC147983) | NP level |
| NCT02397382 | Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis | psoriasis | Caffeine (NPC256849) | NP level |
| NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
| NCT02129075 | A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma | cutaneous melanoma | Lysine (NPC112890) | NP level |
| NCT03333824 | Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer | neoplasm | Caffeine (NPC256849) | NP level |
| NCT01785186 | Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT04354428 | Treatment for COVID-19 in High-Risk Adult Outpatients | COVID-19 | Folic Acid (NPC147983);Ascorbate (NPC187770) | NP level |
| NCT00133562 | HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT00787059 | AC6 Gene Transfer for CHF | congestive heart failure | Sucrose (NPC130683) | NP level |
| NCT05170464 | The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation | memory impairment | Caffeine (NPC256849) | NP level |
| NCT00258245 | Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00080275 | Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00564824 | The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease | coronary artery disease | Caffeine (NPC256849) | NP level |
| NCT02586285 | Effect of S-Adenosyl Methionine Treatment on Recurrence After Curative Resection of Hepatocellular Carcinoma | hepatocellular carcinoma | Methionine (NPC152451) | NP level |
| NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791) | NP level |
| NCT02062190 | Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia | schizophrenia | Resveratrol (NPC161571) | NP level |
| NCT03451266 | Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT02704494 | Resveratrol's Effects in Diabetic Nephropathy | diabetic nephropathy | Resveratrol (NPC161571) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Thiamine (NPC150950);Niacinamide (NPC306397) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT00611000 | Effect of Folate on DNA in Colon Tissue and Blood Samples From Patients at Increased Risk of Developing Colorectal Neoplasia | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01720095 | Niapsan as Add -on Therapy to Antipsychotic Treatment in First Episode Psychosis | psychosis | Niacin (NPC167400) | NP level |
| NCT01852890 | Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT02245932 | Resveratrol In Chronic Obstructive Pulmonary Disease (COPD) Patients (CARMENS-trial) | chronic obstructive pulmonary disease | Resveratrol (NPC161571) | NP level |
| NCT04677049 | Study of Niacin in Glioblastoma | glioblastoma multiforme | Niacin (NPC167400) | NP level |
| NCT00388856 | Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT00000600 | Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up | carotid artery disease;cerebral atherosclerosis;heart disease | Ascorbate (NPC187770) | NP level |
| NCT03680274 | Lessening Organ Dysfunction With VITamin C | COVID-19;Sepsis | Ascorbate (NPC187770) | NP level |
| NCT01755702 | Paracetamol With Caffeine to Treat Episodic Tension Type Headache | Tension-type headache | Caffeine (NPC256849) | NP level |
| NCT00396500 | Deworming and Vitamin A (DEVTA) Prepilot Study | malnutrition;parasitic infection | Retinol (NPC55412) | NP level |
| NCT00626392 | Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01715597 | Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma | uterine fibroid | Ascorbate (NPC187770) | NP level |
| NCT00058123 | Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT00388128 | Caffeine and Intermittent Claudication | intermittent vascular claudication | Caffeine (NPC256849) | NP level |
| NCT02504671 | Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT04643249 | Drug-drug Interaction Study of KL1333 in Healthy Subjects | mitochondrial disease | Caffeine (NPC256849) | NP level |
| NCT01580683 | Vitamin C and Atrial Fibrillation After Cardiac Surgery | atrial fibrillation | Ascorbate (NPC187770) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
GRIA1,GRIA2,GRIA3,GRIN2B,TRPA1,PTGS1,GRIA4,CYP19A1,AKR1B1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
DPP4,ALOX5,RORC,NFKB1,FLT3
FABP5 NCT02397382,NCT02772601,NCT01368887 |
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
CYP3A4,PTGS1,ALOX5,NR3C1,NR3C1,PTGS2,NFKB1
NCT02647086,NCT03556592 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
OR51E2,NOX4,ALOX15,GRIN3A,SLCO1B1,FABP5,SLC6A3
NCT01080352,NCT01912820 |
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04301336,NCT00056433,NCT00508989,NCT01703104,NCT02447874,NCT01142219,NCT00513617,NCT05470998,NCT04055818
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00957359,NCT02245204,NCT00034463,NCT00441870,NCT01983969,NCT02136342,NCT04733534,NCT00441207,NCT01050621
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
NOX4,FLT3,GRIN3A,DPP4,AKR1B1,TSHR,TRPA1,ADORA2A,ALPL
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NPSR1,NOX4,GRM8,CA6,CYP1A1,SLCO1B1,HCAR2,CA9,MET
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
PPARA,DPP4,NFKB1,ESR1
NCT00825695,NCT01130727 NCT02297399,NCT02107976 |
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
FLT3,GRIN2B,EGFR,PTGS2,KDR,SLC6A2,SLC6A4
NCT00930306 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
CDK1,SRC,DPP4,FLT3,TP53,AURKB,MTOR,PIK3CA
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARA
NCT00652431,NCT00203476,NCT00376584,NCT00378833,NCT01583647,NCT00384293,NCT00536510 |
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
KDR,EGFR,TP53,AXL,GSTP1
NCT01902381,NCT00329498,NCT00803530 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
IGF1R,MTOR,GSTP1,TP53,MAPK1,SRC,PTK2,EGFR
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
SLC6A2,SLC6A4,GRIN2B,GRM2,DRD3,SLC6A3,GRM3,NR3C1
|
NADisease Category: NADisease ICD-11 Code: NA |
NOX4,MET
NCT00062556,NCT00388128,NCT01492114,NCT00781196,NCT00071266,NCT04553666 |
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
FLT3,KDR,PTK2,TP53,SRC,MET
NCT00284427,NCT01188876 |
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
NCT03509350,NCT03333278,NCT01590303,NCT03680274,NCT02734147,NCT04999137,NCT01263041 |
AnemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00-3A9Z |
NCT01490944,NCT00443170,NCT01670955,NCT00953134,NCT02225886,NCT00920413,NCT02780505,NCT02631668
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
ADORA2A
NCT00571766,NCT00157521,NCT00974714,NCT03451266,NCT02213094,NCT03419364,NCT00388856 |
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
FFAR1,CYP1A1,ADRA2B,SLC1A1,YES1
NCT00054938,NCT00470522,NCT03260166 |
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
SLCO1B1,NPSR1,AURKB,NOX4,CYP2B6,SLC6A2,CDK1,ALOX15
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PTGS2,HCAR2,ESR1,ADORA2A,ESR2,PTGS1,PPARA
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
PTGS2,GRIN1,PTGS1
NCT00170404,NCT01785186,NCT02563327,NCT01936831 |
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
NR3C1,DPP4,KDR,AURKB,PPARA,AKR1B1,FFAR1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
CA2,ADORA2A,SLC6A2,XDH
NCT01005303,NCT04703361,NCT01115504 |
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
EGFR,DRD3,KDR,ESR1,TP53,SRC,MET
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
RORC
GRIN3A,PTGS2,HCAR2,ALPL NCT03358706,NCT00275418 |
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
EGFR,MET,MTOR,CSNK2A1,KDR,IGF1R
NCT02261844 |
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
KDR,MET,EGFR,TP53,MTOR
NCT01183065,NCT00009841 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
PTGS1,PTGS2,DPP4
NCT00120289,NCT00000541,NCT00000482,NCT03516903 |
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
ADORA2A
NCT00150722,NCT00114400,NCT00120289,NCT01221402,NCT00397657,NCT00127218 |
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
GRIK1,SLC6A2,NR3C1,SLC6A4,SLC6A3,ADRA2B
NCT00437632 |
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000541,NCT00000482,NCT00000461,NCT00000512,NCT00000599,NCT00000555,NCT00000553
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT03333278,NCT03872011,NCT03828929,NCT01070810,NCT04999137,NCT03592693,NCT03649633
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
GRIK1,ALPL,CA12,CDK1,TRPA1,GRM3,GRIA2
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
AKR1C3,PTGS1,GRIA4,GRIN3A,NOX4,ALK,GRM5
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
SLC6A2,TP53,DRD3,KDR,MET,EGFR
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
SLC6A2,SLC6A4,SLC6A3
NCT00495092,NCT00733993,NCT00000324 |
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
GRIK1,GRM2,GRIN2B
NCT02318446,NCT00004758,NCT02369822 |
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT00954525,NCT03797443,NCT01364805,NCT01905150,NCT03956056,NCT01555489
|
Migraine disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SD10 |
NCT03022838,NCT02183688,NCT01248468,NCT01080677,NCT01629329,NCT02582996
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
AKR1C3,AURKB,CA9,CA12,CDK1,XDH
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
FFAR1,PTK2,FLT3,MET,PTGS2,AXL
|
FatigueDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG22 |
SLC6A2
NCT01651793,NCT03288155 NCT00633581,NCT02521077 |
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
ALOX5,KDR
NCT01014546,NCT05025488,NCT00272610 |
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
ADORA2A,MET,TP53,DPP4,HCAR2
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
SRC,KDR,TP53,FLT3,PTK2
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
ESR2,PTGS2,NFKB1,PTGS1,NR3C1
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
GRM5,SLC6A2,SLC6A4,NR3C1,SLC6A3
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
PTGS1,PTGS2
NCT05276895,NCT04783792,NCT02905799 |
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA2,CA6,GRIN1,CA12,CA14
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
KDR,MTOR,CA9,EGFR,MET
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
SRC,NR3C1,ALOX5,PTGS1,PTGS2
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESR2,NR3C1,ADORA2A
NCT02130440,NCT01989897 |
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
SLC6A2,ADRA2B,SLC6A4,SLC6A3,GRIK1
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
MTOR,EGFR,MET,PIK3CB,KDR
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
GRM5,DPP4
NCT00672360,NCT00325572,NCT00965068 |
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
GRIN2B,GRIA1,GRIK1,GRIN2A,GRIN1
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
MET,KDR,MAPK1,EGFR
NCT01783431 |
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
SRC,TP53
NCT00703196,NCT00220532,NCT00284427 |
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ADORA2A,SLC6A2,CA2,MET,AKR1B1
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
ADORA2A,SLC6A4,SLC6A2
NCT00223691,NCT04855266 |
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
PPARA
FABP4 NCT02030977,NCT02541045,NCT03187496 |
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
GRIN2B
NCT03450707,NCT03509662,NCT03640949,NCT04921189 |
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
NCT03768492,NCT01118624,NCT03606967,NCT04616248 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
NCT00120822,NCT02699099,NCT02878265,NCT00147368,NCT00616304
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT00152893,NCT02018965,NCT01949116,NCT02773147,NCT04425902
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT04907253,NCT00564824,NCT00300352,NCT03943459,NCT00134433
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT01999829,NCT00953212,NCT01107730,NCT01580683,NCT03148236
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
ADRA2B,PIM1,TSHR,ALK,GRIK1
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
RORC,ABCG2,GRIA1,GRM1,CA14
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
GRM2,ABCG2,CYP1B1,PTGS2,SLC6A4
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
AXL,YES1,NR3C1,ADORA2A,APP,RORC,CA2,GSTP1,EGFR,CDK1,CA14,MAPK1,CA6,PIM1,MET,PTK2,FLT3,ESR1,ALOX5,PIK3CB,MTOR,ALK,XDH,AURKB,POLB,CSNK2A1,IGF1R,CA9,PTGS1,TP53,PTGS2,FYN,SRC,CA12,NFKB1,KDR,DRD3,PPARA,NQO2,AOX1,PIK3CA,CYP3A4
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
AKR1B1,ABCG2,ALOX5,PTGS1,CA2,NFKB1,NR3C1,PTGS2
NCT02467504,NCT00578305,NCT01711359,NCT01850680,NCT00243412,NCT02293902,NCT01061736,NCT02504671,NCT01010581,NCT02379091,NCT01116141,NCT01217814,NCT01636557,NCT02795299,NCT00299130,NCT00266227,NCT01873443,NCT05363917,NCT00965653,NCT00950989,NCT02930343,NCT03028467,NCT02762838,NCT02393378,NCT00298272,NCT02093026,NCT00299104,NCT04246762,NCT02833350,NCT03172325,NCT03131973,NCT04535427 |
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA6,PTGS1,CA2,CA12
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
EGFR,TP53,SRC,AXL
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT00300365,NCT02114892,NCT02219906 |
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
PTGS2,PTGS1,SLC6A4,SLC6A2
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
PTGS1,PTGS2,AKR1C3,ESR1
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
SLC6A2,SLC6A4
NCT00067899,NCT05452772 |
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1,FLT3
NCT03990766,NCT04898023 |
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
MET,KDR,SRC,MTOR
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
GRM2,DRD3,SLC6A3
NCT01720316 |
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
DRD3,CDK1,EGFR,ALOX5
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
PTGS2,CYP19A1,PTGS1,ESR1
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
NCT03090048,NCT03522922,NCT03626298 |
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
PTGS1,PTGS2
NCT03003000,NCT01468415 |
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
DRD3,TP53,SRC,MTOR
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
CYP3A4,SLC6A4,GRM2,GRM5
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
NCT03446625,NCT01407432,NCT00406874 |
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT02793648,NCT00480207,NCT04670081,NCT04309877
|
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT01502280,NCT01891747,NCT05457959,NCT01792310
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT00133562,NCT00396500,NCT03268902,NCT00338221
|
Iron deficiency anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00 |
NCT03481790,NCT02541708,NCT04268849,NCT03188445
|
AsphyxiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.1 |
NCT01875159,NCT03066115,NCT03321734,NCT04357782
|
PseudohypoparathyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A50.1 |
NCT04240821,NCT04551170,NCT02463409,NCT03029429
|
Deletions of the long arm of chromosome 2Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD44.20 |
NCT04551170,NCT04240821,NCT03029429,NCT02463409
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1,HCAR2,TSHR,CDK1
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
GRIN3A,ALPL,HCAR2,NOX4
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10,PTGS1,GRIA1,NPSR1,CYP2B6,GRM1,CA14,FFAR4,SLC6A4,ALOX15,GRM8,GRIA4,GRIN3A,TP53,DPP4,YES1,PTGS2,POLB,RORC,AKR1B1,TSHR,ALK,CA2,GRIK3,TRPA1,TDP1,FFAR1,ALPL,FABP5,AURKB,CYP19A1,HCAR2,CA9,MET,GSTP1,XDH,GRM3,GRIK1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
PTGS1,OR51E2,ALOX5,CYP1B1,NPSR1,SLC1A1,CYP2B6,FFAR4,CA14,GRM8,ALOX15,AKR1C3,FABP3,NAPRT,ABCG2,SNCA,XDH,PIM1,RECQL,DPP4,PTGS2,POLB,ALK,CA2,GRIK3,TRPA1,LMNA,AXL,ADORA2A,AURKB,HCAR2,CA9,FYN,MET,GSTP1,APP
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HSD17B10,OR51E2,CSNK2A2,NOX4,GRM8,GSTP1,FABP3,GRIN3A,RECQL,CA12,EGFR,AOX1,CDK1,TRIM24,SRC,FABP4,AKR1B1,TSHR,ALK,PPARA,GRIK3,TRPA1,TDP1,LMNA,AXL,FFAR1,PTK2,ESR2,FABP5,AURKB,CA9,MET,TP53,KDR
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
PIK3CB,ALOX5,SLC6A2,AKR1B1,PTGS2,ADRA2B,GRIK1,MTOR,IGF1R,PTGS1,SLC6A4
NCT01426971,NCT04872270,NCT00631111,NCT01796678,NCT01561547,NCT02863575,NCT02174705,NCT03082001,NCT02974114,NCT02990364,NCT04132336,NCT00519207,NCT01842633,NCT02862977,NCT03745963,NCT03272594,NCT01503060,NCT01201954,NCT00482560,NCT03446456,NCT00949104,NCT01190995 |
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
PTGS1,KDR,OR51E2,ALOX5,CSNK2A2,SLC1A1,FLT3,FFAR4,ALOX15,SNCA,PIM1,RECQL,CA12,DPP4,EGFR,AOX1,CDK1,SRC,ALK,TRPA1,TDP1,LMNA,AXL,FFAR1,SULT1A1,AURKB,HCAR2,CA9,SLC6A3,MET,GSTP1,XDH,GRIK1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CSNK2A3,ALOX5,SLC1A1,PIK3CB,NOX4,GRM1,GRIK5,CYP1A2,FFAR4,ALOX15,FABP3,TP53,CA12,ALOX12,YES1,ESR1,GRIA2,RORC,TSHR,ALK,CA2,GRIK3,TDP1,ALPL,FABP5,HCAR2,CA9,MET,GSTP1,XDH
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
NCT03205202 NCT00000161 |
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT01130727
NCT00136188,NCT02704494 |
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1,SLC6A4,ESR2
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
GRIN2B,HCAR2
NCT00796887 |
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
NQO2,SLC6A4,CA2
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
SLC6A2,ESR1,ALK
|
Binge eating disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B82 |
SLC6A3,SLC6A4,SLC6A2
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
NR3C1,CYP19A1,ESR2
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
KDR,MET,TSHR
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
DRD3,SRC,FLT3
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
XDH,ALOX5
NCT02735707 |
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
SRC,TP53
NCT01188876 |
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
APP,IGF1R,NR3C1
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
MET,EGFR
NCT01587261 |
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
FFAR1,FLT3,ALOX5
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1,ALOX5,IGF1R
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1,PTGS1,NR3C1
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
SLC6A3,SLC6A2,SLC6A4
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
TRPA1
NCT02678234,NCT02730364 |
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2,NFKB1
NCT04364750 |
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
NCT00807807,NCT00000600 |
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
SRC,FLT3,FYN
|
Obsessive-compulsive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B20 |
GRIN1
NCT03356483,NCT01031927 |
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
MTOR
NCT01569919,NCT04345705 |
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
PIK3CA
NCT00455416,NCT03121677 |
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
PTGS1
FABP4,NOX4 |
Mixed hyperlipidaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.2 |
NCT00289900,NCT00269204,NCT00269217
|
Neuropathy, ataxia, and retinitis pigmentosaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C73.1 |
NCT00000116,NCT00065455,NCT00000114
|
Vitamin C deficiency, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B56.Z |
NCT02606773,NCT05009355,NCT03224572
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT00256334,NCT04035096,NCT00433576
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FFAR4
NCT03268733,NCT04867252 |
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01417481,NCT01348204,NCT00405665
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT05062486,NCT00000161,NCT00000152
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT04630964,NCT03866174,NCT01263106
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT02586285,NCT05281926,NCT01287585
|
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT03697239,NCT03410030,NCT03908333
|
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT03933163,NCT03761511,NCT01339884
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01525628,NCT01438320,NCT00475176
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT02702492,NCT00626444,NCT00691210
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02730949,NCT02109315,NCT04449198
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT05378919,NCT04801511,NCT00433576
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT05422885,NCT04946383,NCT02523274
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT03359239,NCT04046094,NCT00033436
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
NCT01852890,NCT03541486 |
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
DRD3,AURKB,ABCG2
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1,GRM8,GRM1
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2,GRM1,GRM8
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
MET,HCAR2,AXL
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NR3C1,PTGS1,PTGS2,NFKB1,DPP4,FFAR1,PPARA
NCT04383639,NCT01754662 NCT02440061,NCT00618995,NCT03540758,NCT04504045,NCT00607945,NCT00485758,NCT02744820,NCT01368328,NCT02786823,NCT01839344,NCT05210504,NCT03685773,NCT01319734,NCT00432887,NCT01677611,NCT02549924,NCT03437902 |
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SLC6A3,DRD3,ADORA2A,SRC,GRIA1,GRIA4,GRIA3,GRM5,SNCA,PTGS1,GRIA2,GRIN2B,PTGS2,SLC6A4
NCT03288155 NCT01190735,NCT01738178,NCT03970798,NCT03091543,NCT03094156,NCT00459420,NCT03091868,NCT03093389,NCT03095092,NCT03097211,NCT03095105 |
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
ESR2,CA12,ESR1,NR3C1,CA6,MET,CA9,CA2,CA14,AXL,PIK3CA,EGFR,NQO2,MTOR,KDR,IGF1R,ALK,PIK3CB,CDK1,SRC,CYP19A1
NCT03175341,NCT01276704,NCT02427581,NCT00986609,NCT00908791 |
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
GRM2,PTGS1,OR51E2,GRIA1,SLC1A1,NOX4,GRM1,GRIK5,GRM8,CA14,GRIA4,GRIN3A,SNCA,XDH,GRIA2,RORC,ALK,CA2,GRIK3,NR3C1,ADORA2A,FABP5,MET,SLC6A2,APP,GRIK1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT05029037,NCT04631536,NCT04354428,NCT04400890,NCT04900415,NCT04370288,NCT04851821,NCT04853199,NCT04446104,NCT04363216,NCT05283954,NCT04928495,NCT04335084,NCT04357782,NCT04542993,NCT04334512,NCT04344184,NCT04482686,NCT03680274,NCT04401150,NCT04395768,NCT04347889,NCT04328961,NCT02735707,NCT04703036
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ALOX5,GRM5,GRM8,FFAR4,XDH,ALK,TRPA1,FABP5,AURKB,CYP19A1,CA9,MET,OR51E2,ALOX5,GRM8,FFAR4,GRIA4,TSHR,ALK,GRIK3,TRPA1,FABP5,AURKB,CA9,SLC6A3
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
PTGS1,KDR,ALOX5,NPSR1,PIK3CB,NOX4,SLC1A1,CYP2B6,CA14,FABP3,ABCG2,SNCA,XDH,CA12,DPP4,ALOX12,AKR1B1,MAPK1,TRPA1,ADORA2A,SLCO1B1,FABP5,MET,CDK1,APP
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
EGFR,GSTP1,MET,KDR,ALK,PTGS1,FLT3,PIK3CA,IGF1R,TP53,PIK3CB,ADORA2A
NCT00973609,NCT00611000,NCT04337879,NCT01426490,NCT02969681,NCT00096330,NCT00070434,NCT00002650,NCT02066688,NCT04516681,NCT01661764 |
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
GRM2,PTGS1,CSNK2A3,OR51E2,ALOX5,NOX4,GRIK5,GRM5,SLC6A4,TP53,ALOX12,CDK1,SRC,AKR1B1,TRPA1,LMNA,IGF1R,ESR2,FABP5,AURKB,CA9,SLC6A3,GSTP1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
GRM2,OR51E2,NOX4,AKR1C3,CA12,GRIA2,FABP4,FABP5,CYP19A1,AURKB,CA9,SLC6A3,SLC6A2,CDK1,AKR1C3,TRIM24,SRC,CYP19A1,AURKB,CA9,CA12,CDK1
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
APP,MET,GRM3,KDR,DRD3,GRM5,GRM2,ESR2,SLC6A4,PTGS1,FLT3,PTGS2,SNCA
NCT00056225,NCT00726726,NCT04570085,NCT00692510,NCT00580931,NCT04740580,NCT01504854,NCT01439555 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
OR51E2,GRIA1,NOX4,GRM1,SLC6A4,GSTP1,FABP3,CA12,GRIA2,TRIM24,SRC,FABP4,AKR1B1,ALK,IGF1R,FABP5,AURKB,CYP19A1,SLC6A2,CDK1,GRM3
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
AXL,DRD3,KDR,IGF1R,SRC,MTOR,FYN,FLT3
NCT03964688,NCT00227682,NCT02114502,NCT03602235,NCT00661544,NCT00085345,NCT00469209,NCT00006021,NCT00258245,NCT00317811,NCT02206425,NCT00112879 |
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
KDR,SRC
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
NCT00154700 |
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1,NR3C1
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
FLT3,MTOR
|
Stomach diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA43-DA4Y |
SLC6A2,SLC6A3
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
MTOR,TP53
|
Urinary system diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC2Z |
PTGS1,PTGS2
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
ADORA2A,NFKB1
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
MTOR,EGFR
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NR3C1
NCT04249336 |
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
KDR,SRC
|
Joint painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME82 |
PTGS2,PTGS1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
ALOX5,NFKB1
|
Inherited coagulation factor deficiencyDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B14 |
PTGS2,PTGS1
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
NCT00137124 |
Vitamin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55-5B5F |
AOX1,NR3C1
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
ADORA2A,EGFR
|
Reactive arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA11 |
PTGS1,PTGS2
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2,ESR1
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
PTGS1
NCT03358706 |
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR,ESR2
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR,ALPL
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
PTK2,ESR1
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
PTGS1,PTGS2
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ALK,FLT3
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
MTOR
NCT03253913 |
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH,PPARA
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
HCAR2,PPARA
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
NCT00573313 |
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
SRC,IGF1R
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
GRIN2A,PTGS1
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
GRM3,GRM2
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
CDK1,FLT3
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
EGFR,SRC
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
SLC6A3
NCT02832336 |
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
PTGS1,PTGS2
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MAPK1,MTOR
|
Inflammatory spondyloarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA92 |
PTGS1,PTGS2
|
Parasitic infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D0Y-1G2Z |
ALPL
NCT00396500 |
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53,MTOR
|
Soft tissue disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB56 |
SLC6A4
NCT03508726 |
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NR3C1
NCT00133419 |
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
SLC6A4
NCT00763633 |
Cleft lipDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA40 |
NCT00397917,NCT00098319
|
Other specified infectious meningitis not elsewhere classifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.Y |
NCT05289908,NCT03101579
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00344916,NCT00005107
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT02735707,NCT02186158
|
Spina bifida, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA02.Z |
NCT00452829,NCT00301587
|
Becker muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.0 |
NCT01856868,NCT03236662
|
Essential tremor or related tremorsDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04.1 |
NCT00848172,NCT01468948
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT00691210,NCT03418038
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00058123,NCT00052715
|
Cutaneous T-cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1951 |
NCT00554827,NCT02061449
|
Tuberculosis of the respiratory systemDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10 |
NCT00677339,NCT03882177
|
Age-associated cognitive declineDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.0 |
NCT05170464,NCT01126229
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
NCT04261036,NCT03800667
|
Tension-type headacheDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A81 |
NCT01172405,NCT01755702
|
Peripheral T-cell lymphoma, not otherwise specifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90.C |
NCT02106650,NCT02013362
|
Retinal vascular occlusionDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B74 |
NCT00500045,NCT00493064
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03743636,NCT03861416
|
Schizophrenia or other primary psychotic disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A2Z |
NCT00202280,NCT01720095
|
Cleft palateDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA42 |
NCT00397917,NCT00098319
|
Dental cariesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08.0 |
NCT04750902,NCT02388178
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT04404387,NCT03718507
|
Disorders of calcium or phosphate excretionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB90.48 |
NCT00508885,NCT00316472
|
Asymptomatic stenosis of intracranial or extracranial arteryDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD55 |
NCT00000600,NCT00000599
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
NCT00575848,NCT00222235
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT01985685,NCT00003684
|
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT03581773,NCT02868151
|
FlushingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64.4 |
NCT00536237,NCT00533611
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT02083575,NCT00006136
|
Basal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C32 |
NCT04279535,NCT03769285
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT00634998,NCT04649203
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT05025488,NCT01014546
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04482686,NCT04542993
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT01266018,NCT01931787
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00787059,NCT00344734
|
Cerebrovascular diseases, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B2Z |
NCT00000599,NCT00000600
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT02618824,NCT03088345
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT00433576,NCT01550510
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT01388764,NCT02516085
|
Primary neoplasms of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
NCT03068832,NCT01188096
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT04478734,NCT02336633
|
Noise effects on inner earDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB37 |
NCT02903355,NCT01345474
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
NCT03015675 |
Autosomal dominant polycystic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB81 |
NCT02558595,NCT02140814
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ADORA2A,AXL
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
PTGS2,FABP4
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
TRPA1,DPP4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1,CA9
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MET,HCAR2
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
AKR1B1,GRM2,DRD3,GRM5,ADORA2A,SLC6A4,GRM3
NCT00000372,NCT00268749,NCT00211562,NCT04054973,NCT00005658,NCT00222235,NCT00276263,NCT00291226,NCT02062190,NCT00929370,NCT02067975,NCT00575848 |
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MET,ALK,EGFR,KDR
NCT02420314,NCT02655913,NCT05096663,NCT01194453,NCT02080078,NCT03166254,NCT00609518,NCT01165021,NCT00806819,NCT03370159,NCT00606502,NCT02905591,NCT01799161,NCT03799094,NCT02416739 |
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,CYP1B1,FLT3,FFAR4,CA6,ALOX15,NFKB1,DPP4,TRIM24,AKR1B1,TRPA1,ADORA2A,CYP3A4,FABP5,HCAR2,CA9,SLC6A3,SLC6A2,GRIK1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
OR51E2,SLC1A1,NOX4,GRM1,FABP3,SNCA,CA12,DPP4,NR3C1,FFAR1,CYP3A4,FABP5,AURKB,CYP19A1,CA9,SLC6A3,MET,SLC6A2,CDK1
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
HCAR2,PPARA
NCT00944645,NCT00626392,NCT00943124,NCT00111891,NCT02890992,NCT00961636,NCT01984073,NCT00728910,NCT00903617,NCT01104519,NCT00664287,NCT00376584,NCT00630877,NCT03510884,NCT01071291 |
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
OR51E2,NPSR1,GRM1,CA6,AKR1C3,CA12,ALOX12,GRIA2,TSHR,TRPA1,ADRA2B,SLCO1B1,AURKB,CA9,SLC6A2,CDK1,XDH
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
KDR,CSNK2A3,CYP1B1,CA12,DPP4,PTGS2,AOX1,TSHR,CA2,GRIK3,LMNA,FABP5,CYP19A1,HCAR2,CA9,MET,PTGS1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
CDK1,IGF1R,EGFR,ADORA2A,RORC,ALK,AXL,KDR,MET,GSTP1,FLT3,ALOX5,MTOR
NCT00402883,NCT00033722,NCT03751592 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
PTGS2,NR3C1,ALOX5
NCT01696214,NCT00000578,NCT01057615,NCT02537691,NCT01293734,NCT00756418,NCT00119496,NCT01501942,NCT00252785,NCT00280683,NCT00029679,NCT03269318,NCT00252863 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
MTOR,PTK2,ADORA2A
NCT00825695,NCT01276951 NCT04952051,NCT00520247,NCT00223717,NCT01880866,NCT00345150,NCT04715022,NCT01842399,NCT04832009,NCT03166228,NCT01566565 |
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT00533312,NCT00082251,NCT00269217,NCT00203476,NCT00652431,NCT02409537,NCT01054508,NCT01071525,NCT00080275,NCT00536510,NCT00769132,NCT01321034,NCT03510715,NCT00378833,NCT00271817
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
NPSR1,CYP2B6,GRM8,CA6,ALOX15,ALK,CA2,GRIK3,CYP1A1,ALPL,AURKB,HCAR2,CA9,CDK1,XDH
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
NR3C1,ESR2,PIK3CB,AURKB,AOX1,MTOR,ADORA2A,ESR1,AKR1C3,PIK3CA
NCT02225093,NCT00216099,NCT01607879,NCT05501548 |
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
NPSR1,CYP2B6,GRIK5,CA6,AKR1C3,CA12,TSHR,TRPA1,SLCO1B1,AURKB,CA9,SLC6A3,CDK1,XDH
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
GRM2,GRIA1,CYP1A2,SLC6A4,CA12,CA2,GRIK3,CYP1A1,CYP3A4,AURKB,HCAR2,MET,SLC6A2,GRIK1
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
SLC6A2,SLC6A3,GRM3,SLC6A4,GRM2
NCT05445232,NCT00302289,NCT02048215,NCT01083329,NCT00377975,NCT00204932,NCT02063802,NCT02612259 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
IGF1R,XDH
NCT01356966,NCT01011699,NCT02947750,NCT05284656,NCT00047983,NCT02479451,NCT02848131,NCT02088502,NCT02791906,NCT02258074,NCT02433925 |
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01057589,NCT01596647,NCT02520752,NCT00024310,NCT01517399,NCT03333824,NCT01324115,NCT00951158,NCT02740712,NCT01191216,NCT01920191,NCT00098969,NCT00567931
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
SLC1A1,NOX4,GRM5,GRM8,FABP3,ABCG2,GRIK3,FFAR1,IGF1R,ADORA2A,SULT1A1,GSTP1,APP
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
FFAR1,ALOX5,CYP1B1,ALPL,HCAR2,NOX4,CA12,ALK,DPP4,GRIK3,MET,XDH,GRIA2
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
FFAR1,ADRA2B,ADORA2A,GRIA1,CYP19A1,XDH,GRIK3,GRM1,EGFR,SLC6A2,GRM5,LMNA,AXL
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
AURKB,FLT3,TP53,PIM1,NFKB1,SRC,AXL
NCT01842139,NCT02472626,NCT00329498,NCT00184054,NCT00175812 |
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
SLC1A1,CYP2B6,GRM8,SLC6A4,CA12,ESR1,GRIA2,TRPA1,ADORA2A,AURKB,CA9,CDK1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
OR51E2,CYP1B1,NOX4,FFAR4,DPP4,ESR1,AOX1,ALK,TRPA1,ADRA2B,SULT1A1,FYN
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9,EGFR,MTOR,ALK,DRD3
NCT00998946,NCT00917826,NCT02589145,NCT01983969,NCT02701673,NCT02961816 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
ESR1,GRIN2B,NFKB1,NR3C1,RORC,SRC,GRIN1
NCT01381354,NCT04764383,NCT03266965,NCT00638196 |
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
ADORA2A,NR3C1
NCT00634413,NCT01708278,NCT01599871,NCT00299858,NCT02245932,NCT00241631,NCT03989271,NCT03984188,NCT02340520 |
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
NPSR1,NOX4,GRM8,CA6,ALOX15,SLCO1B1,AURKB,CYP19A1,SLC6A3,MET,CDK1
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
KDR,SRC,HCAR2,PPARA,MET,PTGS1,PTGS2
NCT03679780,NCT00408577,NCT01564381 |
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
SLC6A2,DRD3,SLC6A4,SLC6A3
NCT01685281,NCT02086864,NCT02189772,NCT00995085,NCT01243242,NCT03533556 |
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT03758014,NCT02344355,NCT04677049,NCT00262730,NCT04900792,NCT04201873,NCT02833701,NCT01752491,NCT02017249,NCT02728349
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
NPSR1,NOX4,AKR1C3,PTGS2,FABP4,TRPA1,SLCO1B1,AURKB,CA9,SLC6A2
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ADORA2A,NFKB1,GRIN3A,CYP19A1,HCAR2,DPP4,MET,GRM1,PTGS2,AXL
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
FABP3,GRIK1,SRC,SNCA,NQO2,DPP4,CA2,GSTP1,PTGS2,LMNA
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CDK1,SLCO1B1,CYP3A4,AKR1B1,AURKB,CYP2B6,CA9,CA2,SLC6A2,CYP1A2
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CYP1A1,ADRA2B,ADORA2A,ESR2,PIK3CB,CA2,GRM8,SLC6A2,CA14,ALOX15
|
Age-related macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75.0 |
NCT03205202
|
Diseases of arteries or arterioles, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD5Z |
NCT02876887
|
Essential hypertension, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00.Z |
NCT01130727
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
SLC6A3
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Radionuclide imagingDisease Category: NADisease ICD-11 Code: N.A. |
ADORA2A
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1
|
Adaptive immunity immunodeficiencyDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01 |
NR3C1
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
SLC6A2
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
APP
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
AXL
|
concerning food/fluid intake symptomDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43 |
SLC6A4
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
DRD3
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
Autoimmune diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40-4A45 |
RORC
|
Acute painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG31 |
SLC6A2
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
Otitis externaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA00-AA13 |
NR3C1
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
HydrocephalusDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D64 |
MTOR
|
Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
GRM5
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Genetic prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E02 |
ALPL
|
VasculitisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A44 |
PTGS1
|
Eye anterior segment structural developmental anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA11 |
PTGS1
|
Dystrophic epidermolysis bullosaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC32 |
APP
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
GRM2
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Adrenogenital disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A71 |
NR3C1
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Ataxic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03 |
PTGS1
|
Skin sensation disturbanceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME65 |
GRM5
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
SLC6A2
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Diagnostic imagingDisease Category: NADisease ICD-11 Code: N.A. |
APP
|
Psychoactive substances use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G |
DRD3
|
Desmoid tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7C |
APP
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
DRD3
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
EGFR
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
Knee osteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
PTGS2
|
Intracranial injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07 |
SLC6A3
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Gastroduodenal motor/secretory disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41 |
DRD3
|
Ejaculatory dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA03 |
SLC6A4
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SLC6A4
|
Alpha-1-antitrypsin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C5A |
GRIN2B
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
GRM5
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SLC6A4
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
Spine/trunk injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51 |
NR3C1
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Unspecific substance use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4Z |
ADORA2A
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT00855257
|
Movement disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A07-8A0Z |
NCT01908452
|
Infantile spasmsDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62.0 |
NCT01828437
|
Actinic keratosisDisease Category: X.Extension CodesDisease ICD-11 Code: XH36H6 |
NCT04843553
|
Mycosis fungoidesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B01 |
NCT01134341
|
ParaplegiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB56 |
NCT02314208
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
Migraine with auraDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80.1 |
NCT00471952
|
Infection, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1H0Z |
NCT01275170
|
Recurrent pregnancy lossDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA33 |
NCT01976676
|
Infectious gastroenteritis or colitis without specification of infectious agentDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A40.Z |
NCT00133406
|
Injury of lung, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NB32.3Z |
NCT04344184
|
Burn and burn infectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND90-NE2Z |
NCT00734695
|
Harmful effects of drugs, medicaments or biological substances, not elsewhere classifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE60 |
NCT02908581
|
Impaired glucose toleranceDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.1 |
NCT02621060
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT03493178
|
Retinopathy of prematurityDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71.3 |
NCT01238471
|
Mild hyperemesis gravidarumDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA60.0 |
NCT00861523
|
Inflammatory carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C62 |
NCT00986609
|
Cervical spine painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.0 |
NCT03003000
|
Polycythaemia veraDisease Category: X.Extension CodesDisease ICD-11 Code: XH0453 |
NCT01014546
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101
|
Sezary syndromeDisease Category: X.Extension CodesDisease ICD-11 Code: XH8HN3 |
NCT01134341
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT03752918
|
Argininosuccinic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.A0 |
NCT00345605
|
Disorders of muscles, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB3Z |
NCT03223519
|
Flare or flashDisease Category: X.Extension CodesDisease ICD-11 Code: XE03F |
NCT01140646
|
Rhabdomyosarcoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0GA1 |
NCT01871766
|
Acute promyelocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1A50 |
NCT03624270
|
Other specified inborn errors of energy metabolismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C53.Y |
NCT04643249
|
Diabetic lactic acidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A22.1 |
NCT00143702
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
NCT00120289
|
Pulmonary alveolar proteinosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB04.31 |
NCT03887169
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT01436266
|
Other specified effects of air pressure or water pressureDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NF04.Y |
NCT01902758
|
Injury of spinal cord, level unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51.2 |
NCT02323698
|
GliosarcomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH9RC8 |
NCT02168270
|
Anterior uveitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A96 |
NCT01900431
|
ApnoeaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.0 |
NCT01066728
|
Other specified disorders of carbohydrate absorption or transportDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C61.Y |
NCT02291458
|
Galactose-1-phosphate uridyltransferase deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C51.40 |
NCT03580122
|
Atherosclerotic chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD40.Z |
NCT00804843
|
Disorders of cholesterol synthesisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52.10 |
NCT00272844
|
Aortic valve stenosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB70 |
NCT02109614
|
Oligodendroglioma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH8844 |
NCT02168270
|
Migraine without auraDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80.0 |
NCT00471952
|
Malignant neoplasms of retroperitoneumDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C50 |
NCT01188876
|
Human immunodeficiency virus type 1Disease Category: X.Extension CodesDisease ICD-11 Code: XN8LD |
NCT01426438
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT01953536
|
Degenerative high myopiaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B76 |
NCT00263471
|
Malignant neoplasms of prostate, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.Z |
NCT01017939
|
Malignant neoplasms of gallbladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C13 |
NCT01766219
|
Hereditary sensory or autonomic neuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.Z |
NCT00271635
|
Noninfectious erosive or ulcerative disorders of oral mucosaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01.1 |
NCT04989049
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01686646
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00200746
|
AnorexiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43.7 |
NCT01295450
|
Other specified syndromes with multiple structural anomalies, not of environmental originDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F.1Y |
NCT00446147
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT00218946
|
Impairment of binocular functionsDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9D46 |
NCT02594358
|
Melanoma of skin, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30.Z |
NCT02129075
|
CraniopharyngiomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1AZ2 |
NCT01419067
|
MenopauseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.0 |
NCT00000555
|
Voice disturbances, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MA82.Z |
NCT01435837
|
DNA repair defects other than combined T-cell or B-cell immunodeficienciesDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01.31 |
NCT04870866
|
Clear cell renal cell carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH46F1 |
NCT03334409
|
DysmenorrhoeaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34.3 |
NCT01462370
|
Bacterial infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C41 |
NCT00513110
|
Circadian rhythm sleep disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A60-7A65 |
NCT01468038
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT02985671
|
Carcinoma of male breastDisease Category: X.Extension CodesDisease ICD-11 Code: XH5KW8 |
NCT01042535
|
Vitamin A deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55 |
NCT00128557
|
Acute kidney failure, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60.Z |
NCT02701127
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02756117
|
Other specified diseases of the respiratory systemDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB40.Y |
NCT01416480
|
Nephritic syndromeDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB40 |
NCT01197040
|
Abdominal pelvic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD81 |
NCT00694564
|
DyspnoeaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.5 |
NCT02311088
|
Alcohol dependenceDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40.2 |
NCT01289561
|
BeriberiDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5A.0 |
NCT01864057
|
Relapsing-remitting multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.0 |
NCT01462318
|
Ependymoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1511 |
NCT02125786
|
PorokeratosesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED52 |
NCT04359823
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT04844528
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT05042024
|
Complex regional pain syndromeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30.04 |
NCT02390505
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT02602483
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT02655614
|
Anaplastic large cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1LC0 |
NCT01134341
|
ShockDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG40 |
NCT01587963
|
Carcinomas of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.0 |
NCT03162562
|
Other specified disorders of teeth and supporting structuresDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0A.Y |
NCT05485805
|
Uterine fibroidDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E66 |
NCT01715597
|
Astrocytoma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH96C7 |
NCT02168270
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT02929888
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02424201
|
Autism spectrum disorder without disorder of intellectual development and with mild or no impairment of functional languageDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02.0 |
NCT00965068
|
Macro reentrant atrial tachycardia, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.2Z |
NCT00953212
|
Duplications of the short arm of chromosome 17Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD41.G1 |
NCT00484510
|
Malignant neoplasm metastasis, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E2Z |
NCT03864042
|
Malignant neoplasm metastasis in male genital organsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E06 |
NCT02516670
|
SarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2C35 |
NCT02484391
|
Squamous cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B60-2D01 |
NCT03769285
|
CholangiocarcinomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH7M15 |
NCT01766219
|
Cutaneous lupus erythematosusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EB50-EB5Z |
NCT03260166
|
Insulin-resistance syndromesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A44 |
NCT00654667
|
Acute viral hepatitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50 |
NCT00108589
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT00003808
|
Congenital cytomegalovirus infectionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA62.3 |
NCT00966836
|
MelasmaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60.1 |
NCT01603446
|
CardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43 |
NCT01914081
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
Neurodegenerative disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20-8A23 |
NCT01589809
|
ConcussionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.0 |
NCT01321151
|
FrecklesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED61.0 |
NCT03392623
|
Non-alcoholic steatohepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.1 |
PTGS2
|
Intrauterine growth restrictionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA20.1 |
ADORA2A
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA6
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
HCAR2
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
Plant-Targeted Human Disease Network
>> Targets derived from weak experimental activities
