Plant ID: NPO12044
Plant Latin Name: Dorstenia Barteri
Taxonomy Genus: Dorstenia
Taxonomy Family: Moraceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Cameroon
Ingredient ID: NPC80353
Ingredient ID: NPC78263
Ingredient ID: NPC77672
Ingredient ID: NPC43211
Ingredient ID: NPC36447
Ingredient ID: NPC291854
Ingredient ID: NPC276222
Ingredient ID: NPC269343
Ingredient ID: NPC265146
Ingredient ID: NPC254790
Ingredient ID: NPC233039
Ingredient ID: NPC225531
Ingredient ID: NPC225434
Ingredient ID: NPC223543
Ingredient ID: NPC142319
Ingredient ID: NPC109300
Ingredient ID: NPC105542
Ingredient ID: NPC104159
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Isomerase | P4HB | Protein disulfide-isomerase | P07237 | CHEMBL5422 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 1 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00717652 | Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma | freckles | Arbutin (NPC142319) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
FrecklesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED61.0 |
NCT00717652
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
P4HB
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
P4HB
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
P4HB
|