Target_ID	Gene_Symbol	Protein_Name	Uniprot_ID	ChEMBL_ID	TTD_ID	if_DTP	if_CYP	if_therapeutic_target	Target_Class_Level1	Target_Class_Level2	Target_Class_Level3	Target_Class_level_displayed	Target_type
NPT598	RORB	Nuclear receptor ROR-beta	Q92753	CHEMBL3091268	NA	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT48	KDM4E	Lysine-specific demethylase 4D-like	B2RXH2	CHEMBL1293226	T17036	0	0	1	Epigenetic regulator	Eraser	Lysine demethylase	Lysine demethylase	Therapeutic Target
NPT1448	SGK1	Serine/threonine-protein kinase Sgk1	O00141	CHEMBL2343	T64682	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4567	GRM8	Metabotropic glutamate receptor 8	O00222	CHEMBL3228	T77548	0	0	1	Membrane receptor	Family C G protein-coupled receptor	Small molecule receptor (family C GPCR)	Small molecule receptor (family C GPCR)	Therapeutic Target
NPT4999	MEN1	Menin	O00255	CHEMBL1615381	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT1446	PIK3CD	PI3-kinase p110-delta subunit	O00329	CHEMBL3130	T67849	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT1702	PLK4	Serine/threonine-protein kinase PLK4	O00444	CHEMBL3788	T71374	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1717	STK25	Serine/threonine-protein kinase 25	O00506	CHEMBL5552	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1418	FAAH	Anandamide amidohydrolase	O00519	CHEMBL2243	T34389	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT203	CES2	Carboxylesterase 2	O00748	CHEMBL3180	NA	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT4018	SCD	Acyl-CoA desaturase	O00767	CHEMBL5555	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3334	CIT	Citron Rho-interacting kinase	O14578	CHEMBL5579	T91397	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT956	PTGES	Prostaglandin E synthase	O14684	CHEMBL5658	T02562	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT3441	MAP2K7	Dual specificity mitogen-activated protein kinase kinase 7	O14733	CHEMBL3530	T53159	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT144	TERT	Telomerase reverse transcriptase	O14746	CHEMBL2916	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT1608	CHEK1	Serine/threonine-protein kinase Chk1	O14757	CHEMBL4630	T62449	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT869	FFAR1	Free fatty acid receptor 1	O14842	CHEMBL4422	T25608	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT981	IKBKB	Inhibitor of nuclear factor kappa B kinase beta subunit	O14920	CHEMBL1991	T78429	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1432	AURKA	Serine/threonine-protein kinase Aurora-A	O14965	CHEMBL4722	T87675	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3221	GAK	Serine/threonine-protein kinase GAK	O14976	CHEMBL4355	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3335	DCLK1	Serine/threonine-protein kinase DCLK1	O15075	CHEMBL5683	T42447	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT982	CHUK	Inhibitor of nuclear factor kappa B kinase alpha subunit	O15111	CHEMBL3476	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT538	NPC1	Niemann-Pick C1 protein	O15118	CHEMBL1293277	NA	0	0	1	Transporter	n.a.	n.a.	Transporter	Therapeutic Target
NPT3333	MUSK	Muscle, skeletal receptor tyrosine protein kinase	O15146	CHEMBL5684	T44387	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1540	SLC22A2	Solute carrier family 22 member 2	O15244	CHEMBL1743122	NA	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT613	SLC22A1	Solute carrier family 22 member 1	O15245	CHEMBL5685	NA	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT1614	MAPK13	MAP kinase p38 delta	O15264	CHEMBL2939	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT686	HDAC3	Histone deacetylase 3	O15379	CHEMBL1829	T05090	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT1699	PDPK1	3-phosphoinositide dependent protein kinase-1	O15530	CHEMBL2534	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5301	MLNR	Motilin receptor	O43193	CHEMBL2203	T62306	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT1687	DAPK3	Death-associated protein kinase 3	O43293	CHEMBL2468	T81623	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3442	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	O43318	CHEMBL5776	T04361	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1447	RIPK2	Serine/threonine-protein kinase RIPK2	O43353	CHEMBL5014	T92463	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT497	MGAM	Maltase-glucoamylase	O43451	CHEMBL2074	T92777	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT949	CA12	Carbonic anhydrase XII	O43570	CHEMBL3242	T16987	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT3460	DYRK3	Dual-specificity tyrosine-phosphorylation regulated kinase 3	O43781	CHEMBL4575	T97149	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1270	AKR1B10	Aldo-keto reductase family 1 member B10	O60218	CHEMBL5983	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1660	NUAK1	NUAK family SNF1-like kinase 1	O60285	CHEMBL5784	T21653	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3246	JAK2	Tyrosine-protein kinase JAK2	O60674	CHEMBL2971	T08391	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1282	MITF	Microphthalmia-associated transcription factor	O75030	CHEMBL1741165	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT3107	ROCK2	Rho-associated protein kinase 2	O75116	CHEMBL2973	T06093	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3398	ULK1	Serine/threonine-protein kinase ULK1	O75385	CHEMBL6006	T79307	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1890	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	O75460	CHEMBL1163101	T01003	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT543	NR1I2	Pregnane X receptor	O75469	CHEMBL3401	T82702	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT10	GMNN	Geminin	O75496	CHEMBL1293278	T57387	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT1613	RPS6KA5	Ribosomal protein S6 kinase alpha 5	O75582	CHEMBL4237	T50224	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT45	USP2	Ubiquitin carboxyl-terminal hydrolase 2	O75604	CHEMBL1293227	T95183	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT3374	RPS6KA4	Ribosomal protein S6 kinase alpha 4	O75676	CHEMBL3125	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1708	STK16	Serine/threonine-protein kinase 16	O75716	CHEMBL3938	T04303	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1546	SLC22A3	Solute carrier family 22 member 3	O75751	CHEMBL2073673	T55948	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT346	TRPA1	Transient receptor potential cation channel subfamily A member 1	O75762	CHEMBL6007	T84040	0	0	1	Ion channel	Voltage-gated ion channel	Transient receptor potential channel	Transient receptor potential channel	Therapeutic Target
NPT3247	PAK3	Serine/threonine-protein kinase PAK 3	O75914	CHEMBL2999	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT273	PDE5A	Phosphodiesterase 5A	O76074	CHEMBL1827	T07663	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 5	Phosphodiesterase 5	Therapeutic Target
NPT4736	PDE9A	Phosphodiesterase 9A	O76083	CHEMBL3535	T17852	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 9	Phosphodiesterase 9	Therapeutic Target
NPT3230	STK17B	Serine/threonine-protein kinase 17B	O94768	CHEMBL3980	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1707	STK10	Serine/threonine-protein kinase 10	O94804	CHEMBL3981	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3366	PRKD3	Protein kinase C nu	O94806	CHEMBL2595	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT622	SLCO2B1	Solute carrier organic anion transporter family member 2B1	O94956	CHEMBL1743124	T34064	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT588	TNKS	Tankyrase-1	O95271	CHEMBL6164	T39231	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT713	ABCB11	Bile salt export pump	O95342	CHEMBL6020	T33969	1	0	0	Transporter	Primary active transporter	ATP-binding cassette	ATP-binding cassette	Drug Transporter
NPT3407	MAP3K6	Mitogen-activated protein kinase kinase kinase 6	O95382	CHEMBL1163123	T35283	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4907	TDP2	Tyrosyl-DNA phosphodiesterase 2	O95551	CHEMBL2169736	T04696	0	0	1	Enzyme	Phosphodiesterase	n.a.	Phosphodiesterase	Therapeutic Target
NPT2737	ESRRB	Estrogen-related receptor beta	O95718	CHEMBL3751	T68066	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT3316	MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4	O95819	CHEMBL6166	T71367	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3307	LATS1	Serine/threonine-protein kinase LATS1	O95835	CHEMBL6167	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2993	ABHD16A	Protein BAT5	O95870	CHEMBL6168	NA	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT1695	PAK4	Serine/threonine-protein kinase PAK 4	O96013	CHEMBL4482	T98293	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1680	CHEK2	Serine/threonine-protein kinase Chk2	O96017	CHEMBL2527	T28713	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT94	ALDH1A1	Aldehyde dehydrogenase 1A1	P00352	CHEMBL3577	T99641	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT2818	DHFR	Dihydrofolate reductase	P00374	CHEMBL202	T17345	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT5976	COX2	Cytochrome c oxidase subunit 2	P00403	CHEMBL6174	NA	0	0	1	Transporter	Primary active transporter	Oxidoreduction-driven transporters	Oxidoreduction-driven transporters	Therapeutic Target
NPT2729	ABL1	Tyrosine-protein kinase ABL	P00519	CHEMBL1862	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT285	EGFR	Epidermal growth factor receptor erbB1	P00533	CHEMBL203	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT670	F2	Thrombin	P00734	CHEMBL204	T94033	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT2533	F10	Coagulation factor X	P00742	CHEMBL244	T84631	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT6544	REN	Renin	P00797	CHEMBL286	T61622	0	0	1	Enzyme	Protease	Aspartic protease	Aspartic protease	Therapeutic Target
NPT3838	ADA	Adenosine deaminase	P00813	CHEMBL1910	T03661	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT947	CA1	Carbonic anhydrase I	P00915	CHEMBL261	T13201	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT233	CA2	Carbonic anhydrase II	P00918	CHEMBL205	T20401	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT4054	HRAS	Transforming protein p21/H-Ras-1	P01112	CHEMBL2167	NA	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT516	TNF	TNF-alpha	P01375	CHEMBL1825	NA	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT483	LMNA	Prelamin-A/C	P02545	CHEMBL1293235	NA	0	0	1	Structural protein	n.a.	n.a.	Structural protein	Therapeutic Target
NPT77	TTR	Transthyretin	P02766	CHEMBL3194	NA	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT108	ESR1	Estrogen receptor alpha	P03372	CHEMBL206	T89534	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT4266	ND4	NADH-ubiquinone oxidoreductase chain 4	P03905	CHEMBL4499	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT69	MMP1	Matrix metalloproteinase-1	P03956	CHEMBL332	T52450	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT253	HMGCR	HMG-CoA reductase	P04035	CHEMBL402	T53585	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1424	RAF1	Serine/threonine-protein kinase RAF	P04049	CHEMBL1906	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT503	FUCA1	Alpha-L-fucosidase I	P04066	CHEMBL4176	NA	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT249	NR3C1	Glucocorticoid receptor	P04150	CHEMBL2034	NA	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT2852	PRNP	Prion protein	P04156	CHEMBL4869	T08722	0	0	1	Surface antigen	n.a.	n.a.	Surface antigen	Therapeutic Target
NPT1755	TK1	Thymidine kinase, cytosolic	P04183	CHEMBL2883	T30081	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT895	SHBG	Testis-specific androgen-binding protein	P04278	CHEMBL3305	NA	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT286	ERBB2	Receptor protein-tyrosine kinase erbB-2	P04626	CHEMBL1824	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3239	NTRK1	Nerve growth factor receptor Trk-A	P04629	CHEMBL2815	T07173	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT539	TP53	Cellular tumor antigen p53	P04637	CHEMBL4096	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT1603	CYP1A1	Cytochrome P450 1A1	P04798	CHEMBL2231	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 1	Cytochrome P450 family 1	Cytochrome P450
NPT4947	ATP1A1	Sodium/potassium-transporting ATPase alpha-1 chain	P05023	CHEMBL1807	T40800	0	0	1	Transporter	Primary active transporter	P-type ATPase	P-type ATPase	Therapeutic Target
NPT78	APP	Beta amyloid A4 protein	P05067	CHEMBL2487	NA	0	0	1	Membrane receptor	n.a.	n.a.	Membrane receptor	Therapeutic Target
NPT2732	ALDH2	Aldehyde dehydrogenase	P05091	CHEMBL1935	T99641	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT3159	CYP17A1	Cytochrome P450 17A1	P05093	CHEMBL3522	T89041	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 17	Cytochrome P450 family 17	Cytochrome P450
NPT3953	SERPINE1	Plasminogen activator inhibitor-1	P05121	CHEMBL3475	NA	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT880	PRKCG	Protein kinase C gamma	P05129	CHEMBL2938	T47107	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1634	MPO	Myeloperoxidase	P05164	CHEMBL2439	T23471	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT208	CYP1A2	Cytochrome P450 1A2	P05177	CHEMBL3356	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 1	Cytochrome P450 family 1	Cytochrome P450
NPT802	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P05186	CHEMBL5979	T09538	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT74	JUN	Proto-oncogene c-JUN	P05412	CHEMBL4977	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT760	PRKCB	Protein kinase C beta	P05771	CHEMBL3045	T40276	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5087	HPN	Serine protease hepsin	P05981	CHEMBL2079849	T73471	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT2574	INSR	Insulin receptor	P06213	CHEMBL1981	T85435	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT13	LCK	Tyrosine-protein kinase LCK	P06239	CHEMBL258	T12499	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT14	FYN	Tyrosine-protein kinase FYN	P06241	CHEMBL1841	T17980	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT439	BCHE	Butyrylcholinesterase	P06276	CHEMBL1914	T99799	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT542	PGR	Progesterone receptor	P06401	CHEMBL208	T22939	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT1423	CDK1	Cyclin-dependent kinase 1	P06493	CHEMBL308	T49898	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1667	PYGL	Liver glycogen phosphorylase	P06737	CHEMBL2568	T19184	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT59	POLB	DNA polymerase beta	P06746	CHEMBL2392	T06958	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3067	LPL	Lipoprotein lipase	P06858	CHEMBL2060	T28692	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT4274	EPHX1	Epoxide hydrolase 1	P07099	CHEMBL1968	NA	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT1356	P4HB	Protein disulfide-isomerase	P07237	CHEMBL5422	NA	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT1437	FES	Tyrosine-protein kinase FES	P07332	CHEMBL5455	T29083	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3267	CSF1R	Macrophage colony stimulating factor  receptor	P07333	CHEMBL1844	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1547	CTSD	Cathepsin D	P07339	CHEMBL2581	T67102	0	0	1	Enzyme	Protease	Aspartic protease	Aspartic protease	Therapeutic Target
NPT3579	CAPN1	Calpain 1	P07384	CHEMBL3891	T92517	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT1146	CA3	Carbonic anhydrase III	P07451	CHEMBL2885	NA	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT606	PRSS1	Trypsin I	P07477	CHEMBL209	T27602	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT226	ADRB2	Beta-2 adrenergic receptor	P07550	CHEMBL210	NA	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT469	CTSL	Cathepsin L	P07711	CHEMBL3837	T41141	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT214	CTSB	Cathepsin B	P07858	CHEMBL4072	T61746	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT918	HSP90AA1	Heat shock protein HSP 90-alpha	P07900	CHEMBL3880	T18477	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT1663	YES1	Tyrosine-protein kinase YES	P07947	CHEMBL2073	T75570	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3111	LYN	Tyrosine-protein kinase Lyn	P07948	CHEMBL3905	T68163	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3370	RET	Tyrosine-protein kinase receptor RET	P07949	CHEMBL2041	T60631	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1438	IGF1R	Insulin-like growth factor I receptor	P08069	CHEMBL1957	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1896	GLI1	Zinc finger protein GLI1	P08151	CHEMBL5461	T40890	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT263	CHRM2	Muscarinic acetylcholine receptor M2	P08172	CHEMBL211	T46185	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT265	CHRM4	Muscarinic acetylcholine receptor M4	P08173	CHEMBL1821	T20709	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT668	ABCB1	P-glycoprotein 1	P08183	CHEMBL4302	T25258	1	0	0	Transporter	Primary active transporter	ATP-binding cassette	ATP-binding cassette	Drug Transporter
NPT894	SERPINA6	Corticosteroid binding globulin	P08185	CHEMBL2421	T88452	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT541	NR3C2	Mineralocorticoid receptor	P08235	CHEMBL1994	T72168	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT1429	HSP90AB1	Heat shock protein HSP 90-beta	P08238	CHEMBL4303	T96623	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT568	MMP2	Matrix metalloproteinase-2	P08253	CHEMBL333	NA	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT567	MMP3	Matrix metalloproteinase 3	P08254	CHEMBL283	T86702	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT1337	MET	Hepatocyte growth factor receptor	P08581	CHEMBL3717	T40474	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT225	ADRB1	Beta-1 adrenergic receptor	P08588	CHEMBL213	T44068	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3205	HCK	Tyrosine-protein kinase HCK	P08631	CHEMBL3234	T31406	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT109	CYP3A4	Cytochrome P450 3A4	P08684	CHEMBL340	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 3	Cytochrome P450 family 3	Cytochrome P450
NPT92	HTR1A	Serotonin 1a (5-HT1a) receptor	P08908	CHEMBL214	T78709	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT266	CHRM5	Muscarinic acetylcholine receptor M5	P08912	CHEMBL2035	T79961	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT222	ADRA2A	Alpha-2a adrenergic receptor	P08913	CHEMBL1867	T11448	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3373	ROS1	Proto-oncogene tyrosine-protein kinase ROS	P08922	CHEMBL5568	T69128	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5009	GSTP1	Glutathione S-transferase Pi	P09211	CHEMBL3902	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT2575	PDGFRB	Platelet-derived growth factor receptor beta	P09619	CHEMBL1913	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3112	FGR	Tyrosine-protein kinase FGR	P09769	CHEMBL4454	T49925	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2215	POLA1	DNA polymerase alpha subunit	P09884	CHEMBL1828	T26463	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT570	ALOX5	Arachidonate 5-lipoxygenase	P09917	CHEMBL215	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT2520	LTA4H	Leukotriene A4 hydrolase	P09960	CHEMBL4618	T03691	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT218	ADORA3	Adenosine A3 receptor	P0DMS8	CHEMBL256	T36059	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT4848	HSPA1A	Heat shock 70 kDa protein 1	P0DMV8	CHEMBL5460	T49639	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT5108	GLI2	Zinc finger protein GLI2	P10070	CHEMBL5119	T29672	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT102	CXCL8	Interleukin-8	P10145	CHEMBL2157	T22658	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT60	GAA	Lysosomal alpha-glucosidase	P10253	CHEMBL2608	T31514	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT153	AR	Androgen Receptor	P10275	CHEMBL1871	NA	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT3201	RARA	Retinoic acid receptor alpha	P10276	CHEMBL2055	T94085	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT980	BCL2	Apoptosis regulator Bcl-2	P10415	CHEMBL4860	NA	0	0	1	Ion channel	Other ion channel	Miscellaneous ion channel	Miscellaneous ion channel	Therapeutic Target
NPT628	CYP2C8	Cytochrome P450 2C8	P10632	CHEMBL3721	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT110	CYP2D6	Cytochrome P450 2D6	P10635	CHEMBL289	T57392	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT51	MAPT	Microtubule-associated protein tau	P10636	CHEMBL1293224	NA	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT1479	KIT	Stem cell growth factor receptor	P10721	CHEMBL1936	T57700	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1159	RARB	Retinoic acid receptor beta	P10826	CHEMBL2008	T61657	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT5682	THRA	Thyroid hormone receptor alpha	P10827	CHEMBL1860	T79591	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT46	THRB	Thyroid hormone receptor beta-1	P10828	CHEMBL1947	T98933	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT942	SLC2A1	Glucose transporter	P11166	CHEMBL2535	T89458	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT1394	UMPS	Uridine 5'-monophosphate synthase	P11172	CHEMBL5216	T15851	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT262	CHRM1	Muscarinic acetylcholine receptor M1	P11229	CHEMBL216	T28893	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3960	BCR	Bcr/Abl fusion protein	P11274	CHEMBL5146	NA	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT1265	PIM1	Serine/threonine-protein kinase PIM1	P11309	CHEMBL2147	T50594	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1480	FGFR1	Fibroblast growth factor receptor 1	P11362	CHEMBL3650	T47101	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT143	TOP1	DNA topoisomerase I	P11387	CHEMBL1781	T09826	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT1044	TOP2A	DNA topoisomerase II alpha	P11388	CHEMBL1806	T96144	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT198	VDR	Vitamin D receptor	P11473	CHEMBL1977	T34234	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT2736	ESRRA	Estrogen-related receptor alpha	P11474	CHEMBL3429	T68066	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT240	CYP2A6	Cytochrome P450 2A6	P11509	CHEMBL5282	T06455	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT441	CYP19A1	Cytochrome P450 19A1	P11511	CHEMBL1978	T13260	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 19	Cytochrome P450 family 19	Cytochrome P450
NPT212	CYP2C9	Cytochrome P450 2C9	P11712	CHEMBL3397	T19244	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT2213	CDK4	Cyclin-dependent kinase 4	P11802	CHEMBL331	T85799	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2817	IMPDH2	Inosine-5'-monophosphate dehydrogenase 2	P12268	CHEMBL2002	T89360	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1166	ACE	Angiotensin-converting enzyme	P12821	CHEMBL1808	T82577	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT36	SRC	Tyrosine-protein kinase SRC	P12931	CHEMBL267	T85943	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4181	PEPD	Xaa-Pro dipeptidase	P12955	CHEMBL4185	T94823	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT5980	RARG	Retinoic acid receptor gamma	P13631	CHEMBL2003	T82146	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT677	F3	Coagulation factor III	P13726	CHEMBL4081	T72702	0	0	1	Surface antigen	n.a.	n.a.	Surface antigen	Therapeutic Target
NPT640	SLC5A1	Sodium/glucose cotransporter 1	P13866	CHEMBL4979	T54771	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT227	ADRB3	Beta-3 adrenergic receptor	P13945	CHEMBL246	T51408	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1587	HSD17B1	Estradiol 17-beta-dehydrogenase 1	P14061	CHEMBL3181	T44011	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT6510	CTSE	Cathepsin E	P14091	CHEMBL3092	T16891	0	0	1	Enzyme	Protease	Aspartic protease	Aspartic protease	Therapeutic Target
NPT1250	MIF	Macrophage migration inhibitory factor	P14174	CHEMBL2085	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1384	FDPS	Farnesyl diphosphate synthase	P14324	CHEMBL1782	T86528	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT243	DRD2	Dopamine D2 receptor	P14416	CHEMBL217	T67162	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3286	INSRR	Insulin receptor-related protein	P14616	CHEMBL5483	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT52	PKM	Pyruvate kinase isozymes M1/M2	P14618	CHEMBL1075189	T65889	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT741	TYR	Tyrosinase	P14679	CHEMBL1973	T97035	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT280	MMP9	Matrix metalloproteinase 9	P14780	CHEMBL321	NA	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT1406	GABRA1	GABA receptor alpha-1 subunit	P14867	CHEMBL1962	T51487	0	0	1	Ion channel	Ligand-gated ion channel	GABA-A receptor	GABA-A receptor	Therapeutic Target
NPT1078	IDO1	Indoleamine 2,3-dioxygenase	P14902	CHEMBL4685	T89697	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT645	DAO	D-amino-acid oxidase	P14920	CHEMBL5485	T33124	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1434	BRAF	Serine/threonine-protein kinase B-raf	P15056	CHEMBL5145	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5645	CPA1	Carboxypeptidase A1	P15085	CHEMBL2088	T33966	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT6507	CPB1	Carboxypeptidase B	P15086	CHEMBL2552	T36725	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT142	FABP4	Fatty acid binding protein adipocyte	P15090	CHEMBL2083	T07217	0	0	1	Auxiliary transport protein	Fatty acid binding protein family	n.a.	Fatty acid binding protein family	Therapeutic Target
NPT41	AKR1B1	Aldose reductase	P15121	CHEMBL1900	T26623	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT151	HPGD	15-hydroxyprostaglandin dehydrogenase [NAD+]	P15428	CHEMBL1293255	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3161	CYP11B1	Cytochrome P450 11B1	P15538	CHEMBL1908	T84621	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 11	Cytochrome P450 family 11	Cytochrome P450
NPT935	NQO1	Quinone reductase 1)	P15559	CHEMBL3623	T52389	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT3223	PHKG2	Phosphorylase kinase gamma subunit 2	P15735	CHEMBL2349	T69208	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT792	ALOX15	Arachidonate 15-lipoxygenase	P16050	CHEMBL2903	T16042	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT366	NQO2	Quinone reductase 2	P16083	CHEMBL3959	T75498	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1581	CBR1	Carbonyl reductase [NADPH] 1	P16152	CHEMBL5586	T70518	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT2797	PNLIP	Pancreatic lipase	P16233	CHEMBL1812	T94309	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3020	PDGFRA	Platelet-derived growth factor receptor alpha	P16234	CHEMBL2007	T53524	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT210	TSHR	Thyroid stimulating hormone receptor	P16473	CHEMBL1963	T60606	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT3244	FER	Tyrosine-protein kinase FER	P16591	CHEMBL3982	T16993	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT182	PRKCA	Protein kinase C alpha	P17252	CHEMBL299	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1703	PRKACA	cAMP-dependent protein kinase alpha-catalytic subunit	P17612	CHEMBL4101	T20669	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1210	PTPN2	T-cell protein-tyrosine phosphatase	P17706	CHEMBL3807	T49156	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT2892	XBP1	X-box-binding protein 1	P17861	CHEMBL1741176	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT301	FLT1	Vascular endothelial growth factor receptor 1	P17948	CHEMBL1868	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT178	PTPN1	Protein-tyrosine phosphatase 1B	P18031	CHEMBL335	NA	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT1119	ALOX12	Arachidonate 12-lipoxygenase	P18054	CHEMBL3687	T35527	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT223	ADRA2B	Alpha-2b adrenergic receptor	P18089	CHEMBL1942	T41580	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT224	ADRA2C	Alpha-2c adrenergic receptor	P18825	CHEMBL1916	T01777	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3160	CYP11B2	Cytochrome P450 11B2	P19099	CHEMBL2722	T59056	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 11	Cytochrome P450 family 11	Cytochrome P450
NPT3369	EIF2AK2	Interferon-induced, double-stranded RNA-activated protein kinase	P19525	CHEMBL5785	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3273	CSNK2A2	Casein kinase II alpha (prime)	P19784	CHEMBL4070	T80526	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT546	RXRA	Retinoid X receptor alpha	P19793	CHEMBL2061	T13726	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 2	Nuclear hormone receptor subfamily 2	Therapeutic Target
NPT163	NFKB1	Nuclear factor NF-kappa-B p105 subunit	P19838	CHEMBL3251	T83145	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT264	CHRM3	Muscarinic acetylcholine receptor M3	P20309	CHEMBL245	T67684	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1185	PSMB1	Proteasome component C5	P20618	CHEMBL4208	NA	0	0	1	Enzyme	Protease	Threonine protease	Threonine protease	Therapeutic Target
NPT2536	ITGAL	Leukocyte adhesion glycoprotein LFA-1 alpha	P20701	CHEMBL1803	T35640	0	0	1	Membrane receptor	n.a.	n.a.	Membrane receptor	Therapeutic Target
NPT3410	MAK	Serine/threonine-protein kinase MAK	P20794	CHEMBL1163106	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT627	CYP2B6	Cytochrome P450 2B6	P20813	CHEMBL4729	T11793	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT4023	CYP3A5	Cytochrome P450 3A5	P20815	CHEMBL3019	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 3	Cytochrome P450 family 3	Cytochrome P450
NPT4762	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P20839	CHEMBL1822	T40111	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT261	MAOA	Monoamine oxidase A	P21397	CHEMBL1951	T83875	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT232	CNR1	Cannabinoid CB1 receptor	P21554	CHEMBL218	T76685	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3354	EPHA1	Ephrin type-A receptor 1	P21709	CHEMBL5810	T28418	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT242	DRD1	Dopamine D1 receptor	P21728	CHEMBL2056	T22118	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1481	FGFR2	Fibroblast growth factor receptor 2	P21802	CHEMBL4142	T58454	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT245	DRD4	Dopamine D4 receptor	P21917	CHEMBL219	T24983	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1811	DRD5	Dopamine D5 receptor	P21918	CHEMBL1850	T46828	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT2854	KCNA3	Voltage-gated potassium channel subunit Kv1.3	P22001	CHEMBL4633	T76914	0	0	1	Ion channel	Voltage-gated ion channel	Potassium channels	Potassium channels	Therapeutic Target
NPT204	ACHE	Acetylcholinesterase	P22303	CHEMBL220	T30082	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT901	UGT1A1	UDP-glucuronosyltransferase 1-1	P22309	CHEMBL1287617	T93480	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT3372	FGFR4	Fibroblast growth factor receptor 4	P22455	CHEMBL3973	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3227	FGFR3	Fibroblast growth factor receptor 3	P22607	CHEMBL2742	T91331	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3261	PRKACB	cAMP-dependent protein kinase beta-1 catalytic subunit	P22694	CHEMBL2918	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1062	CA4	Carbonic anhydrase IV	P22748	CHEMBL3729	T53378	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT166	CES1	Acyl coenzyme A:cholesterol acyltransferase	P23141	CHEMBL2265	T76369	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT30	PTGS1	Cyclooxygenase-1	P23219	CHEMBL221	T03403	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1063	CA6	Carbonic anhydrase VI	P23280	CHEMBL3025	T06569	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT426	GLRA1	Glycine receptor subunit alpha-1	P23415	CHEMBL5845	T55285	0	0	1	Ion channel	Ligand-gated ion channel	Glycine receptor	Glycine receptor	Therapeutic Target
NPT1611	RPS6KB1	Ribosomal protein S6 kinase 1	P23443	CHEMBL4501	T94479	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1689	JAK1	Tyrosine-protein kinase JAK1	P23458	CHEMBL2835	T62460	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT912	AHCY	Adenosylhomocysteinase	P23526	CHEMBL2664	T68698	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT228	SLC6A2	Norepinephrine transporter	P23975	CHEMBL222	T21945	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT1008	GABRR1	GABA receptor rho-1 subunit	P24046	CHEMBL3561	T99665	0	0	1	Ion channel	Ligand-gated ion channel	GABA-A receptor	GABA-A receptor	Therapeutic Target
NPT300	TBXAS1	Thromboxane-A synthase	P24557	CHEMBL1835	T78356	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 5	Cytochrome P450 family 5	Cytochrome P450
NPT3124	PRKCH	Protein kinase C eta	P24723	CHEMBL3616	T40149	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1371	CDK2	Cyclin-dependent kinase 2	P24941	CHEMBL301	T70176	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT237	CXCR1	Interleukin-8 receptor A	P25024	CHEMBL4029	T00884	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT221	ADRA1D	Alpha-1d adrenergic receptor	P25100	CHEMBL223	T53381	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT274	PTAFR	Platelet activating factor receptor	P25105	CHEMBL250	T87023	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT2752	DNMT1	DNA (cytosine-5)-methyltransferase 1	P26358	CHEMBL1993	T88304	0	0	1	Epigenetic regulator	Writer	DNA methyltransferase	DNA methyltransferase	Therapeutic Target
NPT582	MAOB	Monoamine oxidase B	P27338	CHEMBL2039	T83011	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT281	MAPK3	MAP kinase ERK1	P27361	CHEMBL3385	T23276	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3280	MARK3	Serine/threonine-protein kinase c-TAK1	P27448	CHEMBL5600	T90553	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1592	DPP4	Dipeptidyl peptidase IV	P27487	CHEMBL284	T31391	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT49	APEX1	DNA-(apurinic or apyrimidinic site) lyase	P27695	CHEMBL5619	T13348	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT2761	PDE4A	Phosphodiesterase 4A	P27815	CHEMBL254	T61744	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 4	Phosphodiesterase 4	Therapeutic Target
NPT1187	PSMB5	Proteasome Macropain subunit MB1	P28074	CHEMBL4662	T49031	0	0	1	Enzyme	Protease	Threonine protease	Threonine protease	Therapeutic Target
NPT974	HTR1D	Serotonin 1d (5-HT1d) receptor	P28221	CHEMBL1983	T11072	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT973	HTR1B	Serotonin 1b (5-HT1b) receptor	P28222	CHEMBL1898	T07806	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT290	HTR2A	Serotonin 2a (5-HT2a) receptor	P28223	CHEMBL224	T32060	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT4219	CHAT	Choline acetylase	P28329	CHEMBL4039	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT292	HTR2C	Serotonin 2c (5-HT2c) receptor	P28335	CHEMBL225	T83813	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT282	MAPK1	MAP kinase ERK2	P28482	CHEMBL4040	T58970	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2776	HTR1E	Serotonin 1e (5-HT1e) receptor	P28566	CHEMBL2182	T84117	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1137	HSD11B1	11-beta-hydroxysteroid dehydrogenase 1	P28845	CHEMBL4235	T65200	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT217	ADORA2A	Adenosine A2a receptor	P29274	CHEMBL251	T77365	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3225	EPHA2	Ephrin type-A receptor 2	P29317	CHEMBL2068	T57278	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3217	EPHA3	Ephrin type-A receptor 3	P29320	CHEMBL4954	T28413	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3216	EPHA8	Ephrin type-A receptor 8	P29322	CHEMBL4134	T58266	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2941	EPHB2	Ephrin type-B receptor 2	P29323	CHEMBL3290	T73756	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3309	LTK	Leukocyte tyrosine kinase receptor	P29376	CHEMBL5627	T47657	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT277	CASP1	Caspase-1	P29466	CHEMBL4801	T98269	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT3974	NOS3	Nitric-oxide synthase, endothelial	P29474	CHEMBL4803	T06046	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3569	NOS1	Nitric-oxide synthase, brain	P29475	CHEMBL3568	T16117	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3276	TYK2	Tyrosine-protein kinase TYK2	P29597	CHEMBL3553	T78932	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3060	CDC25A	Dual specificity phosphatase Cdc25A	P30304	CHEMBL3775	T30823	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT911	CDC25B	Dual specificity phosphatase Cdc25B	P30305	CHEMBL4804	T46365	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT1659	AXL	Tyrosine-protein kinase receptor UFO	P30530	CHEMBL4895	T82383	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT216	ADORA1	Adenosine A1 receptor	P30542	CHEMBL226	NA	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT4358	AGTR1	Type-1 angiotensin II receptor	P30556	CHEMBL227	T74456	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT5256	HTR1F	Serotonin 1f (5-HT1f) receptor	P30939	CHEMBL1805	T78656	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT641	SLC5A2	Sodium/glucose cotransporter 2	P31639	CHEMBL3884	NA	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT6142	GABRA5	GABA receptor alpha-5 subunit	P31644	CHEMBL5112	T26368	0	0	1	Ion channel	Ligand-gated ion channel	GABA-A receptor	GABA-A receptor	Therapeutic Target
NPT295	SLC6A4	Serotonin transporter	P31645	CHEMBL228	T27812	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT728	AKT1	Serine/threonine-protein kinase AKT	P31749	CHEMBL4282	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1430	AKT2	Serine/threonine-protein kinase AKT2	P31751	CHEMBL2431	T62753	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT476	ATIC	AICAR transformylase	P31939	CHEMBL2518	T04741	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT4729	CCKBR	Cholecystokinin B receptor	P32239	CHEMBL298	T05849	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT424	CHRNA3	Neuronal acetylcholine receptor subunit alpha-3	P32297	CHEMBL3068	T54931	0	0	1	Ion channel	Ligand-gated ion channel	Nicotinic acetylcholine receptor	Nicotinic acetylcholine receptor	Therapeutic Target
NPT3447	GRK4	G protein-coupled receptor kinase 4	P32298	CHEMBL5861	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2871	CDA	Cytidine deaminase	P32320	CHEMBL4502	T79027	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT213	CYP2C19	Cytochrome P450 2C19	P33261	CHEMBL3622	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT1594	ABCC1	Multidrug resistance-associated protein 1	P33527	CHEMBL3004	T11288	1	0	0	Transporter	Primary active transporter	ATP-binding cassette	ATP-binding cassette	Drug Transporter
NPT6141	GABRA3	GABA receptor alpha-3 subunit	P34903	CHEMBL3026	T62292	0	0	1	Ion channel	Ligand-gated ion channel	GABA-A receptor	GABA-A receptor	Therapeutic Target
NPT862	EPHX2	Epoxide hydratase	P34913	CHEMBL2409	T35734	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT3457	GRK5	G protein-coupled receptor kinase 5	P34947	CHEMBL5678	T69612	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1785	HTR7	Serotonin 7 (5-HT7) receptor	P34969	CHEMBL3155	T79062	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1287	CNR2	Cannabinoid CB2 receptor	P34972	CHEMBL253	T37693	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT5318	CRHR1	Corticotropin releasing factor receptor 1	P34998	CHEMBL1800	T45262	0	0	1	Membrane receptor	Family B G protein-coupled receptor	Peptide receptor (family B GPCR)	Peptide receptor (family B GPCR)	Therapeutic Target
NPT1143	CA5A	Carbonic anhydrase VA	P35218	CHEMBL4789	NA	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT3517	NOS2	Nitric oxide synthase, inducible	P35228	CHEMBL4481	T02703	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1788	ADRA1A	Alpha-1a adrenergic receptor	P35348	CHEMBL229	T92609	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT31	PTGS2	Cyclooxygenase-2	P35354	CHEMBL230	T66665	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT251	HRH1	Histamine H1 receptor	P35367	CHEMBL231	T77913	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1789	ADRA1B	Alpha-1b adrenergic receptor	P35368	CHEMBL232	T29500	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT145	OPRM1	Mu opioid receptor	P35372	CHEMBL233	T47768	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT599	RORA	Nuclear receptor ROR-alpha	P35398	CHEMBL5868	T43206	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT244	DRD3	Dopamine D3 receptor	P35462	CHEMBL234	T02551	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3716	SCN1A	Sodium channel protein type I alpha subunit	P35498	CHEMBL1845	T58440	1	0	0	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Drug Transporter
NPT3713	SCN4A	Sodium channel protein type IV alpha subunit	P35499	CHEMBL2072	T02546	1	0	0	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Drug Transporter
NPT4448	GCK	Hexokinase type IV	P35557	CHEMBL3820	T87166	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT5020	GRK3	Beta-adrenergic receptor kinase 2	P35626	CHEMBL1075166	T57174	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT155	AHR	Aryl hydrocarbon receptor	P35869	CHEMBL3201	T23666	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT2573	FLT4	Vascular endothelial growth factor receptor 3	P35916	CHEMBL1955	T07303	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1478	KDR	Vascular endothelial growth factor receptor 2	P35968	CHEMBL279	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1690	MAP2K2	Dual specificity mitogen-activated protein kinase kinase 2	P36507	CHEMBL2964	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT410	CHRNA7	Neuronal acetylcholine receptor protein alpha-7 subunit	P36544	CHEMBL2492	T34429	0	0	1	Ion channel	Ligand-gated ion channel	Nicotinic acetylcholine receptor	Nicotinic acetylcholine receptor	Therapeutic Target
NPT1650	FLT3	Tyrosine-protein kinase receptor FLT3	P36888	CHEMBL1974	T74312	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3304	ACVRL1	Serine/threonine-protein kinase receptor R3	P37023	CHEMBL5311	T36959	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT958	HSD17B3	Estradiol 17-beta-dehydrogenase 3	P37058	CHEMBL4234	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1588	HSD17B2	Estradiol 17-beta-dehydrogenase 2	P37059	CHEMBL2789	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT99	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	CHEMBL235	NA	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT920	SNCA	Alpha-synuclein	P37840	CHEMBL6152	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT157	BRCA1	Breast cancer type 1 susceptibility protein	P38398	CHEMBL5990	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3744	GRIK1	Glutamate receptor ionotropic kainate 1	P39086	CHEMBL1918	T73495	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT1089	MMP12	Matrix metalloproteinase 12	P39900	CHEMBL4393	T03500	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT96	THPO	Thrombopoietin	P40225	CHEMBL1293256	T99379	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT38	STAT3	Signal transducer and activator of transcription 3	P40763	CHEMBL4026	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT271	OPRD1	Delta opioid receptor	P41143	CHEMBL236	T58992	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT272	OPRK1	Kappa opioid receptor	P41145	CHEMBL237	T60693	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT3826	P2RY2	Purinergic receptor P2Y2	P41231	CHEMBL4398	T93515	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3113	CSK	Tyrosine-protein kinase CSK	P41240	CHEMBL2634	T08741	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4519	SLC19A1	Folate transporter 1	P41440	CHEMBL4833	T35465	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3549	GRM5	Metabotropic glutamate receptor 5	P41594	CHEMBL3227	T99347	0	0	1	Membrane receptor	Family C G protein-coupled receptor	Small molecule receptor (family C GPCR)	Small molecule receptor (family C GPCR)	Therapeutic Target
NPT291	HTR2B	Serotonin 2b (5-HT2b) receptor	P41595	CHEMBL1833	T31204	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3394	PRKCI	Protein kinase C iota	P41743	CHEMBL2598	T83174	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT37	STAT1	Signal transducer and activator of transcription 1-alpha/beta	P42224	CHEMBL6101	T64205	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT3741	GRIA1	Glutamate receptor ionotropic, AMPA 1	P42261	CHEMBL2009	T33584	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT3742	GRIA2	Glutamate receptor ionotropic, AMPA 2	P42262	CHEMBL4016	T42392	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT3504	AKR1C3	Aldo-keto-reductase family 1 member C3	P42330	CHEMBL4681	T60857	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1444	PIK3CA	PI3-kinase p110-alpha subunit	P42336	CHEMBL4005	T80276	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT3376	PIK3CB	PI3-kinase p110-beta subunit	P42338	CHEMBL3145	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT940	MTOR	Serine/threonine-protein kinase mTOR	P42345	CHEMBL2842	T75243	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT979	CASP3	Caspase-3	P42574	CHEMBL2334	T57943	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT3388	MATK	Tyrosine-protein kinase CTK	P42679	CHEMBL4175	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3351	TEC	Tyrosine-protein kinase TEC	P42680	CHEMBL4246	T15848	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3272	TXK	Tyrosine-protein kinase TXK	P42681	CHEMBL4367	T32590	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3214	ABL2	Tyrosine-protein kinase ABL2	P42684	CHEMBL4014	T83009	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3204	FRK	Tyrosine-protein kinase FRK	P42685	CHEMBL4223	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1197	HTT	Huntingtin	P42858	CHEMBL5514	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT955	CA7	Carbonic anhydrase VII	P43166	CHEMBL2326	T37541	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT101	GLP1R	Glucagon-like peptide 1 receptor	P43220	CHEMBL1784	T36075	0	0	1	Membrane receptor	Family B G protein-coupled receptor	Peptide receptor (family B GPCR)	Peptide receptor (family B GPCR)	Therapeutic Target
NPT3595	CTSK	Cathepsin K	P43235	CHEMBL268	T11388	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT4088	GRK6	G protein-coupled receptor kinase 6	P43250	CHEMBL6144	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1274	RAD52	DNA repair protein RAD52 homolog	P43351	CHEMBL2362978	NA	0	0	1	Other nuclear protein	n.a.	n.a.	Other nuclear protein	Therapeutic Target
NPT3259	ZAP70	Tyrosine-protein kinase ZAP-70	P43403	CHEMBL2803	T64553	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1449	SYK	Tyrosine-protein kinase SYK	P43405	CHEMBL2599	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1426	MAPK8	c-Jun N-terminal kinase 1	P45983	CHEMBL2276	T40097	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1427	MAPK9	c-Jun N-terminal kinase 2	P45984	CHEMBL4179	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3319	MAP2K4	Dual specificity mitogen-activated protein kinase kinase 4	P45985	CHEMBL2897	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT47	RECQL	ATP-dependent DNA helicase Q1	P46063	CHEMBL1293236	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT425	HTR3A	Serotonin 3a (5-HT3a) receptor	P46098	CHEMBL1899	T64591	0	0	1	Ion channel	Ligand-gated ion channel	5HT3 receptor	5HT3 receptor	Therapeutic Target
NPT6127	BDKRB1	Bradykinin B1 receptor	P46663	CHEMBL4308	T58589	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT3281	MAP2K3	Dual specificity mitogen-activated protein kinase kinase 3	P46734	CHEMBL2109	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT6140	GABRA2	GABA receptor alpha-2 subunit	P47869	CHEMBL4956	T51452	0	0	1	Ion channel	Ligand-gated ion channel	GABA-A receptor	GABA-A receptor	Therapeutic Target
NPT1814	GCGR	Glucagon receptor	P47871	CHEMBL1985	NA	0	0	1	Membrane receptor	Family B G protein-coupled receptor	Peptide receptor (family B GPCR)	Peptide receptor (family B GPCR)	Therapeutic Target
NPT1784	HTR5A	Serotonin 5a (5-HT5a) receptor	P47898	CHEMBL3426	T15571	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3825	P2RY1	Purinergic receptor P2Y1	P47900	CHEMBL4315	T67818	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT967	XDH	Xanthine dehydrogenase	P47989	CHEMBL1929	T40954	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT4046	MTNR1A	Melatonin receptor 1A	P48039	CHEMBL1945	T97613	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3743	GRIA4	Glutamate receptor ionotropic, AMPA 4	P48058	CHEMBL3190	T96235	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT1591	PREP	Prolyl endopeptidase	P48147	CHEMBL3202	T86161	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT5981	RXRG	Retinoid X receptor gamma	P48443	CHEMBL2004	T46456	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 2	Nuclear hormone receptor subfamily 2	Therapeutic Target
NPT3168	CSNK1A1	Casein kinase I alpha	P48729	CHEMBL2793	T13075	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3266	CSNK1D	Casein kinase I delta	P48730	CHEMBL2828	T72915	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1445	PIK3CG	PI3-kinase p110-gamma subunit	P48736	CHEMBL3267	T95913	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT2961	TDO2	Tryptophan 2,3-dioxygenase	P48775	CHEMBL2140	T44818	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1441	MAPKAPK2	MAP kinase-activated protein kinase 2	P49137	CHEMBL2208	T21307	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4047	MTNR1B	Melatonin receptor 1B	P49286	CHEMBL1946	T48268	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3324	CDK8	Cell division protein kinase 8	P49336	CHEMBL5719	T10822	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1681	CLK1	Dual specificty protein kinase CLK1	P49759	CHEMBL4224	T51468	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1682	CLK2	Dual specificity protein kinase CLK2	P49760	CHEMBL4225	T51468	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1683	CLK3	Dual specificity protein kinase CLK3	P49761	CHEMBL4226	T51468	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT676	GSK3A	Glycogen synthase kinase-3 alpha	P49840	CHEMBL2850	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT591	GSK3B	Glycogen synthase kinase-3 beta	P49841	CHEMBL262	T70977	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5968	HNMT	Histamine N-methyltransferase	P50135	CHEMBL2190	T17448	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT2581	SULT1A1	Sulfotransferase 1A1	P50225	CHEMBL1743291	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT294	HTR6	Serotonin 6 (5-HT6) receptor	P50406	CHEMBL3371	T16691	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT5373	METAP2	Methionine aminopeptidase 2	P50579	CHEMBL3922	T75596	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT3346	CDK7	Cyclin-dependent kinase 7	P50613	CHEMBL3055	T58449	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3347	CDK9	Cyclin-dependent kinase 9	P50750	CHEMBL3116	T44458	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT537	RAB9A	Ras-related protein Rab-9A	P51151	CHEMBL1293294	T66350	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT103	RORC	Nuclear receptor ROR-gamma	P51449	CHEMBL1741186	T25307	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT3312	BLK	Tyrosine-protein kinase BLK	P51451	CHEMBL2250	T74307	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2674	P2RX1	P2X purinoceptor 1	P51575	CHEMBL2094	T69091	0	0	1	Ion channel	Ligand-gated ion channel	P2X receptor	P2X receptor	Therapeutic Target
NPT3386	IRAK1	Interleukin-1 receptor-associated kinase 1	P51617	CHEMBL3357	T63846	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1110	CCR6	C-C chemokine receptor type 6	P51684	CHEMBL4423	NA	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT1705	RPS6KA3	Ribosomal protein S6 kinase alpha 3	P51812	CHEMBL2345	T03279	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2750	BMX	Tyrosine-protein kinase BMX	P51813	CHEMBL3834	T99990	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3262	PRKX	Serine/threonine-protein kinase PRKX	P51817	CHEMBL5818	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1658	NEK2	Serine/threonine-protein kinase NEK2	P51955	CHEMBL3835	T49102	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3396	NEK4	Serine/threonine-protein kinase Nek4	P51957	CHEMBL5819	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1336	PGD	6-phosphogluconate dehydrogenase	P52209	CHEMBL3404	T76497	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT1440	JAK3	Tyrosine-protein kinase JAK3	P52333	CHEMBL2148	T23172	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1691	MAP2K6	Dual specificity mitogen-activated protein kinase kinase 6	P52564	CHEMBL2171	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT831	PLK1	Serine/threonine-protein kinase PLK1	P53350	CHEMBL3024	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1721	DAPK1	Death-associated protein kinase 1	P53355	CHEMBL2558	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT946	ACLY	ATP-citrate synthase	P53396	CHEMBL3720	T52189	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT3242	LIMK1	LIM domain kinase 1	P53667	CHEMBL3836	T70840	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3278	LIMK2	LIM domain kinase 2	P53671	CHEMBL5932	T09133	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1615	MAPK12	MAP kinase p38 gamma	P53778	CHEMBL4674	T79798	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3207	MAPK10	c-Jun N-terminal kinase 3	P53779	CHEMBL2637	T85421	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT58	BLM	Bloom syndrome protein	P54132	CHEMBL1293237	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT5836	CACNA2D1	Voltage-gated calcium channel alpha2/delta subunit 1	P54289	CHEMBL1919	T84316	0	0	1	Auxiliary transport protein	Calcium channel auxiliary subunit alpha2delta family	n.a.	Calcium channel auxiliary subunit alpha2delta family	Therapeutic Target
NPT3969	ATP12A	Potassium-transporting ATPase alpha chain 2	P54707	CHEMBL2933	NA	1	0	0	Enzyme	Hydrolase	n.a.	Hydrolase	Drug Transporter
NPT3219	EPHA5	Ephrin type-A receptor 5	P54756	CHEMBL3987	T18474	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2572	EPHB4	Ephrin type-B receptor 4	P54760	CHEMBL5147	T49507	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3212	EPHB1	Ephrin type-B receptor 1	P54762	CHEMBL5072	T02446	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3218	EPHA4	Ephrin type-A receptor 4	P54764	CHEMBL3988	T70234	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4559	F2RL1	Proteinase-activated receptor 2	P55085	CHEMBL5963	T62841	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT1226	CASP7	Caspase-7	P55210	CHEMBL3468	T72252	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT867	CASP6	Caspase-6	P55212	CHEMBL3308	NA	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT2629	GFER	FAD-linked sulfhydryl oxidase ALR	P55789	CHEMBL1741189	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT2675	P2RX3	P2X purinoceptor 3	P56373	CHEMBL2998	T17140	0	0	1	Ion channel	Ligand-gated ion channel	P2X receptor	P2X receptor	Therapeutic Target
NPT688	HDAC4	Histone deacetylase 4	P56524	CHEMBL3524	T63816	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT740	BACE1	Beta-secretase 1	P56817	CHEMBL4822	T79031	0	0	1	Enzyme	Protease	Aspartic protease	Aspartic protease	Therapeutic Target
NPT3349	SIK1	Serine/threonine-protein kinase SIK1	P57059	CHEMBL6082	T11317	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3820	EIF4A1	Eukaryotic initiation factor 4A-I	P60842	CHEMBL2052028	NA	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3033	ESRRG	Estrogen-related receptor gamma	P62508	CHEMBL4245	T68066	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT5887	PPIA	Cyclophilin A	P62937	CHEMBL1949	T47081	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT4166	FKBP1A	FK506-binding protein 1A	P62942	CHEMBL1902	T76059	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT4171	FKBP1B	FK506-binding protein 1B	P68106	CHEMBL2430	NA	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT1598	CSNK2A1	Casein kinase II alpha	P68400	CHEMBL3629	T51565	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2930	HBB	Hemoglobin beta chain	P68871	CHEMBL4331	T31825	0	0	1	Secreted protein	n.a.	n.a.	Secreted protein	Therapeutic Target
NPT3292	SRPK2	Serine/threonine-protein kinase SRPK2	P78362	CHEMBL5668	T58924	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3326	MAP3K9	Mitogen-activated protein kinase kinase kinase 9	P80192	CHEMBL2872	T19760	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1138	HSD11B2	11-beta-hydroxysteroid dehydrogenase 2	P80365	CHEMBL3746	T43721	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT154	SMAD3	Mothers against decapentaplegic homolog 3	P84022	CHEMBL1293258	T35445	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT3345	CDK3	Cyclin-dependent kinase 3	Q00526	CHEMBL4442	T22956	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1571	CDK6	Cyclin-dependent kinase 6	Q00534	CHEMBL2508	T89361	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3240	CDK5	Cyclin-dependent kinase 5	Q00535	CHEMBL4036	T20973	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3728	MDM2	p53-binding protein Mdm-2	Q00987	CHEMBL5023	NA	0	0	1	Other nuclear protein	n.a.	n.a.	Other nuclear protein	Therapeutic Target
NPT796	PMP22	Peripheral myelin protein 22	Q01453	CHEMBL1293298	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT5235	FABP5	Fatty acid binding protein epidermal	Q01469	CHEMBL3674	T21507	0	0	1	Auxiliary transport protein	Fatty acid binding protein family	n.a.	Fatty acid binding protein family	Therapeutic Target
NPT246	SLC6A3	Dopamine transporter	Q01959	CHEMBL238	T55959	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT761	PRKCE	Protein kinase C epsilon	Q02156	CHEMBL3582	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT491	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1	Q02750	CHEMBL3587	T35940	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2576	TEK	Tyrosine-protein kinase TIE-2	Q02763	CHEMBL4128	T92144	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3327	MAP3K10	Mitogen-activated protein kinase kinase kinase 10	Q02779	CHEMBL2873	T89323	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4371	FKBP4	FK506 binding protein 4	Q02790	CHEMBL4050	T87020	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT322	TOP2B	DNA topoisomerase II beta	Q02880	CHEMBL3396	T96144	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT1038	KMT2A	Histone-lysine N-methyltransferase MLL	Q03164	CHEMBL1293299	T25462	0	0	1	Epigenetic regulator	Writer	Protein methyltransferase	Protein methyltransferase	Therapeutic Target
NPT106	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	CHEMBL3979	T85042	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT721	RELA	Nuclear factor NF-kappa-B p65 subunit	Q04206	CHEMBL5533	T83145	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT5086	HGFAC	Hepatocyte growth factor activator	Q04756	CHEMBL3351190	T38584	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT887	PRKCQ	Protein kinase C theta	Q04759	CHEMBL3920	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1566	GLO1	Glyoxalase I	Q04760	CHEMBL2424	T88285	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT3287	ACVR1	Activin receptor type-1	Q04771	CHEMBL5903	T12091	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT6226	CHRNE	Acetylcholine receptor protein epsilon chain	Q04844	CHEMBL2484	NA	0	0	1	Ion channel	Ligand-gated ion channel	Nicotinic acetylcholine receptor	Nicotinic acetylcholine receptor	Therapeutic Target
NPT3390	MST1R	Macrophage-stimulating protein receptor	Q04912	CHEMBL2689	T01973	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1436	PTK2	Focal adhesion kinase 1	Q05397	CHEMBL2695	T15068	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3455	PRKCZ	Protein kinase C zeta	Q05513	CHEMBL3438	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT881	PRKCD	Protein kinase C delta	Q05655	CHEMBL2996	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT833	BTK	Tyrosine-protein kinase BTK	Q06187	CHEMBL5251	T25005	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2742	AOX1	Aldehyde oxidase	Q06278	CHEMBL3257	T94444	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT3277	TYRO3	Tyrosine-protein kinase receptor TYRO3	Q06418	CHEMBL5314	T94880	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1283	PAX8	Paired box protein Pax-8	Q06710	CHEMBL2362980	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT4735	PDE4B	Phosphodiesterase 4B	Q07343	CHEMBL275	T10265	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 4	Phosphodiesterase 4	Therapeutic Target
NPT2796	BCL2L1	Apoptosis regulator Bcl-X	Q07817	CHEMBL4625	NA	0	0	1	Ion channel	Other ion channel	Miscellaneous ion channel	Miscellaneous ion channel	Therapeutic Target
NPT57	MCL1	Induced myeloid leukemia cell differentiation protein Mcl-1	Q07820	CHEMBL4361	NA	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT866	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	CHEMBL239	T86591	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT3245	TNK2	Tyrosine kinase non-receptor protein 2	Q07912	CHEMBL4599	T63220	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT6124	CYP24A1	Cytochrome P450 24A1	Q07973	CHEMBL4521	T92458	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 24	Cytochrome P450 family 24	Cytochrome P450
NPT284	PPP3CA	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	Q08209	CHEMBL4445	T25464	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT3342	DDR1	Epithelial discoidin domain-containing receptor 1	Q08345	CHEMBL5319	T09185	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1464	PDE4D	Phosphodiesterase 4D	Q08499	CHEMBL288	T02001	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 4	Phosphodiesterase 4	Therapeutic Target
NPT5446	ADCY1	Brain adenylate cyclase 1	Q08828	CHEMBL2899	T63609	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1439	ITK	Tyrosine-protein kinase ITK/TSK	Q08881	CHEMBL2959	T91761	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1688	DMPK	Myotonin-protein kinase	Q09013	CHEMBL5320	T68766	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5283	FUT7	Alpha-(1,3)-fucosyltransferase 7	Q11130	CHEMBL3596077	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT4185	SREBF2	Sterol regulatory element-binding protein 2	Q12772	CHEMBL1795166	T03385	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT98	KCNH2	HERG	Q12809	CHEMBL240	T20251	1	0	0	Ion channel	Voltage-gated ion channel	Potassium channels	Potassium channels	Drug Transporter
NPT3406	MAP4K2	Mitogen-activated protein kinase kinase kinase kinase 2	Q12851	CHEMBL5330	T07191	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3412	MAP3K12	Mitogen-activated protein kinase kinase kinase 12	Q12852	CHEMBL1908389	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3320	MERTK	Proto-oncogene tyrosine-protein kinase MER	Q12866	CHEMBL5331	T55781	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3737	GRIK2	Glutamate receptor ionotropic kainate 2	Q13002	CHEMBL3683	T58178	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT3746	GRIK3	Glutamate receptor ionotropic kainate 3	Q13003	CHEMBL3684	T68876	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT1711	STK4	Serine/threonine-protein kinase MST1	Q13043	CHEMBL4598	T47164	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT28	PLA2G7	LDL-associated phospholipase A2	Q13093	CHEMBL3514	T69912	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT1794	NR1H3	LXR-alpha	Q13133	CHEMBL2808	T52297	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT3120	PAK1	Serine/threonine-protein kinase PAK 1	Q13153	CHEMBL4600	T37961	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3440	MAP2K5	Dual specificity mitogen-activated protein kinase kinase 5	Q13163	CHEMBL4948	T17143	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1442	PAK2	Serine/threonine-protein kinase PAK 2	Q13177	CHEMBL4487	T07766	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3331	STK3	Serine/threonine-protein kinase MST2	Q13188	CHEMBL4708	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3411	MAP3K1	Mitogen-activated protein kinase kinase kinase 1	Q13233	CHEMBL3956	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3368	PRKG2	cGMP-dependent protein kinase 2	Q13237	CHEMBL2896	T23606	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1259	GRM1	Metabotropic glutamate receptor 1	Q13255	CHEMBL3772	T27137	0	0	1	Membrane receptor	Family C G protein-coupled receptor	Small molecule receptor (family C GPCR)	Small molecule receptor (family C GPCR)	Therapeutic Target
NPT524	ATM	Serine-protein kinase ATM	Q13315	CHEMBL3797	T97196	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2715	PTPRS	Receptor-type tyrosine-protein phosphatase S	Q13332	CHEMBL2396508	T10147	0	0	1	Enzyme	Phosphatase	Protein Phosphatase	Protein Phosphatase	Therapeutic Target
NPT6515	ADAM9	ADAM9	Q13443	CHEMBL5982	T03672	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT4170	FKBP5	Peptidyl-prolyl cis-trans isomerase FKBP5	Q13451	CHEMBL2052031	T98337	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT592	ROCK1	Rho-associated protein kinase 1	Q13464	CHEMBL3231	T51282	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3297	TNK1	Non-receptor tyrosine-protein kinase TNK1	Q13470	CHEMBL5334	T91598	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5199	TUBB3	Tubulin beta-3 chain	Q13509	CHEMBL2597	NA	0	0	1	Structural protein	n.a.	n.a.	Structural protein	Therapeutic Target
NPT755	PIN1	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Q13526	CHEMBL2288	T16308	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT4884	ATR	Serine-protein kinase ATR	Q13535	CHEMBL5024	T97155	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT684	HDAC1	Histone deacetylase 1	Q13547	CHEMBL325	T68547	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT1630	CAMK2B	CaM kinase II beta	Q13554	CHEMBL4121	T18299	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1676	CAMK2G	CaM kinase II gamma	Q13555	CHEMBL3829	T18299	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1675	CAMK2D	CaM kinase II delta	Q13557	CHEMBL2801	T18299	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3114	DYRK1A	Dual-specificity tyrosine-phosphorylation regulated kinase 1A	Q13627	CHEMBL2292	T92803	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4011	HTR4	Serotonin 4 (5-HT4) receptor	Q13639	CHEMBL1875	T59679	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3215	PTK6	Tyrosine-protein kinase BRK	Q13882	CHEMBL4601	T73694	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3970	KLF5	Kruppel-like factor 5	Q13887	CHEMBL1293249	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT2691	CACNA1C	Voltage-gated L-type calcium channel alpha-1C subunit	Q13936	CHEMBL1940	T51115	1	0	0	Ion channel	Voltage-gated ion channel	Voltage-gated calcium channel	Voltage-gated calcium channel	Drug Transporter
NPT3367	PRKG1	cGMP-dependent protein kinase 1 beta	Q13976	CHEMBL4273	T56035	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3232	CAMK1	CaM kinase I alpha	Q14012	CHEMBL2493	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3275	IKBKE	Inhibitor of nuclear factor kappa B kinase epsilon subunit	Q14164	CHEMBL3529	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3263	PTK2B	Protein tyrosine kinase 2 beta	Q14289	CHEMBL5469	T07087	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5104	PDE3A	Phosphodiesterase 3A	Q14432	CHEMBL241	T88975	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 3	Phosphodiesterase 3	Therapeutic Target
NPT2856	SCN5A	Sodium channel protein type V alpha subunit	Q14524	CHEMBL1980	T39716	0	0	1	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Therapeutic Target
NPT3282	MELK	Maternal embryonic leucine zipper kinase	Q14680	CHEMBL4578	T96892	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3604	NR1I3	Nuclear receptor subfamily 1 group I member 3	Q14994	CHEMBL5503	T69506	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT3174	KARS1	Lysyl-tRNA synthetase	Q15046	CHEMBL5575	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1443	PDK1	Pyruvate dehydrogenase kinase isoform 1	Q15118	CHEMBL4766	T15776	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4110	EBP	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase	Q15125	CHEMBL4931	T25317	0	0	1	Enzyme	Isomerase	n.a.	Isomerase	Therapeutic Target
NPT3364	PRKD1	Protein kinase C mu	Q15139	CHEMBL3863	T47885	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1710	STK38	Serine/threonine-protein kinase 38	Q15208	CHEMBL1075155	T03581	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1435	ERBB4	Receptor protein-tyrosine kinase erbB-4	Q15303	CHEMBL3009	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3234	RPS6KA2	Ribosomal protein S6 kinase alpha 2	Q15349	CHEMBL3906	T28043	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3211	EPHA7	Ephrin type-A receptor 7	Q15375	CHEMBL4602	T57006	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4712	P2RY14	Purinergic receptor P2Y14	Q15391	CHEMBL4518	T16555	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT4169	SF3B3	Splicing factor 3B subunit 3	Q15393	CHEMBL1250378	NA	0	0	1	Other nuclear protein	n.a.	n.a.	Other nuclear protein	Therapeutic Target
NPT3106	RPS6KA1	Ribosomal protein S6 kinase alpha 1	Q15418	CHEMBL2553	T83202	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1898	SHH	Sonic hedgehog protein	Q15465	CHEMBL5602	T12075	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT3352	TESK1	Dual specificity testis-specific protein kinase 1	Q15569	CHEMBL5604	T49542	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5886	ELAVL1	ELAV-like protein 1	Q15717	CHEMBL1250379	T78349	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT3068	LTB4R	Leukotriene B4 receptor 1	Q15722	CHEMBL3911	T59626	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT2626	MYLK	Myosin light chain kinase, smooth muscle	Q15746	CHEMBL2428	T97141	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4146	TAB1	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1	Q15750	CHEMBL5605	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT1616	MAPK11	MAP kinase p38 beta	Q15759	CHEMBL3961	T55729	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3279	STK11	Serine/threonine-protein kinase 11	Q15831	CHEMBL5606	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3395	GRK1	Rhodopsin kinase	Q15835	CHEMBL5607	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3708	SCN9A	Sodium channel protein type IX alpha subunit	Q15858	CHEMBL4296	T12119	1	0	0	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Drug Transporter
NPT6625	ATP6AP1	Vacuolar ATP synthase subunit S1	Q15904	CHEMBL4790	NA	0	0	1	Transporter	Primary active transporter	F-type and V-type ATPases	F-type and V-type ATPases	Therapeutic Target
NPT152	NFE2L2	Nuclear factor erythroid 2-related factor 2	Q16236	CHEMBL1075094	T88505	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT3271	NTRK3	NT-3 growth factor receptor	Q16288	CHEMBL5608	T51076	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3745	GRIK5	Glutamate receptor ionotropic kainate 5	Q16478	CHEMBL2675	T87930	0	0	1	Ion channel	Ligand-gated ion channel	Ionotropic glutamate receptor	Ionotropic glutamate receptor	Therapeutic Target
NPT1656	PKN1	Protein kinase N1	Q16512	CHEMBL3384	T60003	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3357	PKN2	Protein kinase N2	Q16513	CHEMBL3032	T94197	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT283	MAPK14	MAP kinase p38 alpha	Q16539	CHEMBL260	T65864	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1677	CAMK4	CaM kinase IV	Q16566	CHEMBL2494	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3328	MAP3K11	Mitogen-activated protein kinase kinase kinase 11	Q16584	CHEMBL2708	T12126	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3270	NTRK2	Neurotrophic tyrosine kinase receptor type 2	Q16620	CHEMBL4898	T84703	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT93	SMN1	Survival motor neuron protein	Q16637	CHEMBL1293232	NA	0	0	1	Epigenetic regulator	Reader	Methyl-lysine/arginine binding protein	Methyl-lysine/arginine binding protein	Therapeutic Target
NPT211	HIF1A	Hypoxia-inducible factor 1 alpha	Q16665	CHEMBL4261	NA	0	0	1	Transcription factor	n.a.	n.a.	Transcription factor	Therapeutic Target
NPT1604	CYP1B1	Cytochrome P450 1B1	Q16678	CHEMBL4878	T92521	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 1	Cytochrome P450 family 1	Cytochrome P450
NPT2599	CYP2A13	Cytochrome P450 2A13	Q16696	CHEMBL3542436	NA	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 2	Cytochrome P450 family 2	Cytochrome P450
NPT948	CA9	Carbonic anhydrase IX	Q16790	CHEMBL3594	T64567	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT3224	PHKG1	Phosphorylase kinase gamma subunit 1	Q16816	CHEMBL4004	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3303	DDR2	Discoidin domain-containing receptor 2	Q16832	CHEMBL5122	T11764	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2217	CYP51A1	Cytochrome P450 51	Q16850	CHEMBL3849	T32972	0	1	0	Enzyme	Cytochrome P450	Cytochrome P450 family 51	Cytochrome P450 family 51	Cytochrome P450
NPT4407	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	CHEMBL2331053	T23787	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3167	MPEG1	Macrophage-expressed gene 1 protein	Q2M385	CHEMBL3414409	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT3446	MYLK3	Myosin light chain kinase	Q32MK0	CHEMBL4627	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT665	SLC22A6	Solute carrier family 22 member 6	Q4U2R8	CHEMBL1641347	NA	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3380	SBK1	Serine/threonine-protein kinase SBK1	Q52WX2	CHEMBL1163129	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4409	PDCD4	Programmed cell death protein 4	Q53EL6	CHEMBL1781868	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT3434	MAP3K19	SPS1/STE20-related protein kinase YSK4	Q56UN5	CHEMBL6191	T42157	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4003	FFAR4	G-protein coupled receptor 120	Q5NUL3	CHEMBL5339	T51385	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3448	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2	Q5S007	CHEMBL1075104	T08123	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3329	CDC42BPA	Serine/threonine-protein kinase MRCK-A	Q5VT25	CHEMBL4516	T00075	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3306	CDC42BPG	Serine/threonine-protein kinase MRCK gamma	Q6DT37	CHEMBL5615	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3341	NEK5	Serine/threonine-protein kinase Nek5	Q6P3R8	CHEMBL5044	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3382	ULK3	Serine/threonine-protein kinase ULK3	Q6PHR2	CHEMBL5047	T16188	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1416	NPSR1	Neuropeptide S receptor	Q6W5P4	CHEMBL5162	T20958	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT3451	DSTYK	Dual serine/threonine and tyrosine protein kinase	Q6XUX3	CHEMBL1908386	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3812	SLCO4C1	Solute carrier organic anion transporter family member 4C1	Q6ZQN7	CHEMBL2073690	T36053	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3235	MARK2	MAP/microtubule affinity-regulating kinase 2	Q7KZI7	CHEMBL3831	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3431	TAOK1	Serine/threonine-protein kinase TAO1	Q7L7X3	CHEMBL5261	T97016	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3269	TLK2	Serine/threonine-protein kinase tousled-like 2	Q86UE8	CHEMBL5404	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3257	STK32C	Serine/threonine-protein kinase 32C	Q86UX6	CHEMBL5405	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1701	PIM3	Serine/threonine-protein kinase PIM3	Q86V86	CHEMBL5407	T16596	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4036	SLC47A2	Multidrug and toxin extrusion protein 2	Q86VL8	CHEMBL1743127	T78127	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3255	MYLK4	Myosin light chain kinase family member 4	Q86YV6	CHEMBL5426	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3444	HIPK1	Homeodomain-interacting protein kinase 1	Q86Z02	CHEMBL5427	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1672	CAMK1D	CaM kinase I delta	Q8IU85	CHEMBL5073	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3311	MAP4K3	Mitogen-activated protein kinase kinase kinase kinase 3	Q8IVH8	CHEMBL5432	T46000	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1612	MAPKAPK5	MAP kinase-activated protein kinase 5	Q8IW41	CHEMBL3094	T29754	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3344	BRSK2	BR serine/threonine-protein kinase 2	Q8IWQ3	CHEMBL4574	T10375	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3445	NIM1K	Serine/threonine-protein kinase NIM1	Q8IY84	CHEMBL3542	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3422	ULK2	Serine/threonine-protein kinase ULK2	Q8IYT8	CHEMBL5435	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3101	CA13	Carbonic anhydrase XIII	Q8N1Q1	CHEMBL3912	NA	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT2994	ABHD12	Monoacylglycerol lipase ABHD12	Q8N2K0	CHEMBL5516	NA	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3381	MINK1	Misshapen-like kinase 1	Q8N4C8	CHEMBL5518	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3336	DCLK2	Serine/threonine-protein kinase DCLK2	Q8N568	CHEMBL5519	T63298	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3248	CAMKK1	CaM-kinase kinase alpha	Q8N5S9	CHEMBL5256	T38134	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2983	DAGLB	Sn1-specific diacylglycerol lipase beta	Q8NCG7	CHEMBL5521	T15509	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT3439	HIPK4	Homeodomain-interacting protein kinase 4	Q8NE63	CHEMBL1075167	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT472	TRPV1	Vanilloid receptor	Q8NER1	CHEMBL4794	NA	0	0	1	Ion channel	Voltage-gated ion channel	Transient receptor potential channel	Transient receptor potential channel	Therapeutic Target
NPT3338	MYO3A	Myosin IIIA	Q8NEV4	CHEMBL5546	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3443	NEK11	Serine/threonine-protein kinase Nek11	Q8NG66	CHEMBL5638	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3363	MAPK15	Mitogen-activated protein kinase 15	Q8TD08	CHEMBL5198	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3241	NEK9	Serine/threonine-protein kinase NEK9	Q8TD19	CHEMBL5257	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3315	BRSK1	BR serine/threonine-protein kinase 1	Q8TDC3	CHEMBL5650	T20053	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT525	HCAR2	Hydroxycarboxylic acid receptor 2	Q8TDS4	CHEMBL3785	T88185	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT745	GPBAR1	G-protein coupled bile acid receptor 1	Q8TDU6	CHEMBL5409	T86273	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT6631	GANC	Neutral alpha-glucosidase C	Q8TET4	CHEMBL2520	T61339	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT4093	HASPIN	Serine/threonine-protein kinase haspin	Q8TF76	CHEMBL1075163	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3438	GRK7	G protein-coupled receptor kinase 7	Q8WTQ7	CHEMBL1075133	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT690	HDAC7	Histone deacetylase 7	Q8WUI4	CHEMBL2716	T98698	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT3339	MYO3B	Myosin-IIIB	Q8WXR4	CHEMBL5654	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3399	DYRK2	Dual-specificity tyrosine-phosphorylation regulated kinase 2	Q92630	CHEMBL4376	T39486	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT248	ESR2	Estrogen receptor beta	Q92731	CHEMBL242	T80896	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 3	Nuclear hormone receptor subfamily 3	Therapeutic Target
NPT685	HDAC2	Histone deacetylase 2	Q92769	CHEMBL1937	T51191	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT5649	HDAC10	Histone deacetylase 10	Q969S8	CHEMBL5103	T94324	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT3418	SGK3	Serine/threonine-protein kinase Sgk3	Q96BR1	CHEMBL6186	T64102	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5648	HDAC11	Histone deacetylase 11	Q96DB2	CHEMBL3310	T97903	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT1046	SIRT1	NAD-dependent deacetylase sirtuin 1	Q96EB6	CHEMBL4506	T14731	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT4037	SLC47A1	Multidrug and toxin extrusion protein 1	Q96FL8	CHEMBL1743126	T39676	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3829	P2RY11	Purinergic receptor P2Y11	Q96G91	CHEMBL4867	T92689	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1433	AURKB	Serine/threonine-protein kinase Aurora-B	Q96GD4	CHEMBL2185	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1713	PBK	PDZ-binding kinase	Q96KB5	CHEMBL4896	T98642	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Q96KQ7	CHEMBL6032	T53251	0	0	1	Epigenetic regulator	Writer	Protein methyltransferase	Protein methyltransferase	Therapeutic Target
NPT3318	MARK4	MAP/microtubule affinity-regulating kinase 4	Q96L34	CHEMBL5754	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1673	CAMK1G	CaM kinase I gamma	Q96NX5	CHEMBL5258	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3462	TSSK2	Testis-specific serine/threonine-protein kinase 2	Q96PF2	CHEMBL6014	T04413	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3340	NEK1	Serine/threonine-protein kinase Nek1	Q96PY6	CHEMBL5855	T43031	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3454	PASK	PAS domain-containing serine/threonine-protein kinase	Q96RG2	CHEMBL6054	T37371	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT540	NR1H4	Bile acid receptor FXR	Q96RI1	CHEMBL2047	T51426	0	0	1	Transcription factor	Nuclear receptor	Nuclear hormone receptor subfamily 1	Nuclear hormone receptor subfamily 1	Therapeutic Target
NPT976	TAAR1	Trace amine-associated receptor 1	Q96RJ0	CHEMBL5857	T99524	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT1678	CAMKK2	CaM-kinase kinase beta	Q96RR4	CHEMBL5284	T82262	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3291	SRPK1	Serine/threonine-protein kinase SRPK1	Q96SB4	CHEMBL4375	T94201	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3715	SCN2A	Sodium channel protein type II alpha subunit	Q99250	CHEMBL4187	T29678	0	0	1	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Therapeutic Target
NPT3037	GPER1	G-protein coupled estrogen receptor 1	Q99527	CHEMBL5872	T65236	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT4954	P2RX4	P2X purinoceptor 4	Q99571	CHEMBL2104	T60330	0	0	1	Ion channel	Ligand-gated ion channel	P2X receptor	P2X receptor	Therapeutic Target
NPT1431	MAP3K5	Mitogen-activated protein kinase kinase kinase 5	Q99683	CHEMBL5285	T97589	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3000	MGLL	Monoglyceride lipase	Q99685	CHEMBL4191	T18664	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT149	HSD17B10	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Q99714	CHEMBL4159	NA	0	0	1	Enzyme	Oxidoreductase	n.a.	Oxidoreductase	Therapeutic Target
NPT296	SIGMAR1	Sigma opioid receptor	Q99720	CHEMBL287	T46360	0	0	1	Membrane receptor	n.a.	n.a.	Membrane receptor	Therapeutic Target
NPT3389	MAP3K3	Mitogen-activated protein kinase kinase kinase 3	Q99759	CHEMBL5970	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2879	SLC29A1	Equilibrative nucleoside transporter 1	Q99808	CHEMBL1997	T13491	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT1099	SMO	Smoothened homolog	Q99835	CHEMBL5971	T66505	0	0	1	Membrane receptor	Frizzled family G protein-coupled receptor	Smoothened receptor (frizzled family GPCR)	Smoothened receptor (frizzled family GPCR)	Therapeutic Target
NPT1569	CTRC	Chymotrypsin C	Q99895	CHEMBL2386	T10118	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT5152	FUCA2	Alpha-L-fucosidase 2	Q9BTY2	CHEMBL2271	NA	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3283	MKNK1	MAP kinase-interacting serine/threonine-protein kinase MNK1	Q9BUB5	CHEMBL4718	T97136	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3004	ABHD6	Monoacylglycerol lipase ABHD6	Q9BV23	CHEMBL2189127	T81452	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3323	CDK19	Cell division cycle 2-like protein kinase 6	Q9BWU1	CHEMBL6002	T98034	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3299	TSSK1B	Testis-specific serine/threonine-protein kinase 1	Q9BXA7	CHEMBL6003	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT6513	EBPL	Emopamil-binding protein-like	Q9BY08	CHEMBL2311238	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT687	HDAC8	Histone deacetylase 8	Q9BY41	CHEMBL3192	T28887	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT3296	STK33	Serine/threonine-protein kinase 33	Q9BYT3	CHEMBL6005	T17552	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3365	PRKD2	Serine/threonine-protein kinase D2	Q9BZL6	CHEMBL4900	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1257	SENP6	Sentrin-specific protease 6	Q9GZR1	CHEMBL1741215	NA	0	0	1	Enzyme	Protease	Cysteine protease	Cysteine protease	Therapeutic Target
NPT3348	NUAK2	NUAK family SNF1-like kinase 2	Q9H093	CHEMBL5698	T55005	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3290	SIK2	Serine/threonine-protein kinase SIK2	Q9H0K1	CHEMBL5699	T30495	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3243	MYLK2	myosin light chain kinase 2	Q9H1R3	CHEMBL2777	T98198	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1706	SLK	Serine/threonine-protein kinase 2	Q9H2G2	CHEMBL4202	T57307	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2563	TNKS2	Tankyrase-2	Q9H2K2	CHEMBL6154	T38087	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT3427	TAOK3	Serine/threonine-protein kinase TAO3	Q9H2K8	CHEMBL5701	T63682	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3432	HIPK2	Homeodomain-interacting protein kinase 2	Q9H2X6	CHEMBL4576	T53952	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT988	HRH4	Histamine H4 receptor	Q9H3N8	CHEMBL3759	T26500	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3409	HIPK3	Homeodomain-interacting protein kinase 3	Q9H422	CHEMBL4577	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3358	PLK3	Serine/threonine-protein kinase PLK3	Q9H4B4	CHEMBL4897	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3231	CLK4	Dual specificity protein kinase CLK4	Q9HAZ1	CHEMBL4203	T51468	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3213	MKNK2	MAP kinase signal-integrating kinase 2	Q9HBH9	CHEMBL4204	T99160	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT2944	RXFP1	Relaxin receptor 1	Q9HBX9	CHEMBL1293316	T73696	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Peptide receptor (family A GPCR)	Peptide receptor (family A GPCR)	Therapeutic Target
NPT3456	SGK2	Serine/threonine-protein kinase Sgk2	Q9HBY8	CHEMBL5794	T64102	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1627	GPR35	G-protein coupled receptor 35	Q9HC97	CHEMBL1293267	T56143	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT72	SLCO1B3	Solute carrier organic anion transporter family member 1B3	Q9NPD5	CHEMBL1743121	T02565	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT1606	NOX4	NADPH oxidase 4	Q9NPH5	CHEMBL1250375	T29741	0	0	1	Enzyme	n.a.	n.a.	Enzyme	Therapeutic Target
NPT1697	PAK6	Serine/threonine-protein kinase PAK6	Q9NQU5	CHEMBL4311	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3429	SNRK	SNF-related serine/threonine-protein kinase	Q9NRH2	CHEMBL1908384	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3308	LATS2	Serine/threonine-protein kinase LATS2	Q9NRM7	CHEMBL5907	T18390	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT50	TDP1	Tyrosyl-DNA phosphodiesterase 1	Q9NUW8	CHEMBL1075138	T33492	0	0	1	Enzyme	Phosphodiesterase	n.a.	Phosphodiesterase	Therapeutic Target
NPT3425	IRAK4	Interleukin-1 receptor-associated kinase 4	Q9NWZ3	CHEMBL3778	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3714	SCN3A	Sodium channel protein type III alpha subunit	Q9NY46	CHEMBL5163	T76937	0	0	1	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Therapeutic Target
NPT3300	STK32B	Serine/threonine-protein kinase 32B	Q9NY57	CHEMBL5912	T01255	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5493	SLC5A4	Low affinity sodium-glucose cotransporter	Q9NY91	CHEMBL1770047	T22583	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT3258	MAP3K20	Mixed lineage kinase 7	Q9NYL2	CHEMBL3886	T97821	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3414	PLK2	Serine/threonine-protein kinase PLK2	Q9NYY3	CHEMBL5938	T59654	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3904	ERAP1	Endoplasmic reticulum aminopeptidase 1	Q9NZ08	CHEMBL5939	T72849	0	0	1	Enzyme	Protease	Metallo protease	Metallo protease	Therapeutic Target
NPT3317	MARK1	Serine/threonine-protein kinase MARK1	Q9P0L2	CHEMBL5940	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1700	PIM2	Serine/threonine-protein kinase PIM2	Q9P1W9	CHEMBL4523	T07279	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1696	PAK5	Serine/threonine-protein kinase PAK7	Q9P286	CHEMBL4524	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1693	STK26	Serine/threonine-protein kinase MST4	Q9P289	CHEMBL5941	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3537	DNMT3B	DNA (cytosine-5)-methyltransferase 3B	Q9UBC3	CHEMBL6095	T65501	0	0	1	Epigenetic regulator	Reader	Methyl-lysine/arginine binding protein	Methyl-lysine/arginine binding protein	Therapeutic Target
NPT3285	NLK	Serine/threonine protein kinase NLK	Q9UBE8	CHEMBL5364	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT692	HDAC6	Histone deacetylase 6	Q9UBN7	CHEMBL1865	T22274	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT6508	RPS6KB2	Ribosomal protein S6 kinase 2	Q9UBS0	CHEMBL3111	T42760	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1407	GABBR1	GABA-B receptor 1	Q9UBS5	CHEMBL2064	T42446	0	0	1	Membrane receptor	Family C G protein-coupled receptor	Small molecule receptor (family C GPCR)	Small molecule receptor (family C GPCR)	Therapeutic Target
NPT1709	STK17A	Serine/threonine-protein kinase 17A	Q9UEE5	CHEMBL4525	T91323	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3416	STK39	STE20/SPS1-related proline-alanine-rich protein kinase	Q9UEW8	CHEMBL1163108	T67837	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3220	EPHA6	Ephrin type-A receptor 6	Q9UF33	CHEMBL4526	T08647	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3417	TBK1	Serine/threonine-protein kinase TBK1	Q9UHD2	CHEMBL5408	T63024	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3711	SCN11A	Sodium channel protein type XI alpha subunit	Q9UI33	CHEMBL5167	T34123	0	0	1	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Therapeutic Target
NPT3236	DAPK2	Death-associated protein kinase 2	Q9UIK4	CHEMBL3123	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3254	RPS6KA6	Ribosomal protein S6 kinase alpha 6	Q9UK32	CHEMBL4924	T95878	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1712	TNIK	TRAF2- and NCK-interacting kinase	Q9UKE5	CHEMBL4527	T72534	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3268	TLK1	Serine/threonine-protein kinase tousled-like 1	Q9UKI8	CHEMBL5388	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT691	HDAC9	Histone deacetylase 9	Q9UKV0	CHEMBL4145	T03687	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT3426	TAOK2	Serine/threonine-protein kinase TAO2	Q9UL54	CHEMBL1075195	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT954	CA14	Carbonic anhydrase XIV	Q9ULX7	CHEMBL3510	T31992	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT1661	ALK	ALK tyrosine kinase receptor	Q9UM73	CHEMBL4247	T56418	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT8	POLI	DNA polymerase iota	Q9UNA4	CHEMBL5391	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT6363	CELA1	Elastase 1	Q9UNI1	CHEMBL3000	T22839	0	0	1	Enzyme	Protease	Serine protease	Serine protease	Therapeutic Target
NPT1422	ABCG2	ATP-binding cassette sub-family G member 2	Q9UNQ0	CHEMBL5393	T56556	1	0	0	Transporter	Primary active transporter	ATP-binding cassette	ATP-binding cassette	Drug Transporter
NPT2887	PHF8	Histone lysine demethylase PHF8	Q9UPP1	CHEMBL1938212	T00933	0	0	1	Epigenetic regulator	Reader	Plant homeodomain	Plant homeodomain	Therapeutic Target
NPT3423	CILK1	Serine/threonine-protein kinase ICK	Q9UPZ9	CHEMBL1163126	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3206	AURKC	Serine/threonine-protein kinase Aurora-C	Q9UQB9	CHEMBL3935	T97592	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3712	SCN8A	Sodium channel protein type VIII alpha subunit	Q9UQD0	CHEMBL5202	T58741	1	0	0	Ion channel	Voltage-gated ion channel	Voltage-gated sodium channel	Voltage-gated sodium channel	Drug Transporter
NPT689	HDAC5	Histone deacetylase 5	Q9UQL6	CHEMBL2563	T07930	0	0	1	Epigenetic regulator	Eraser	Histone deacetylase	Histone deacetylase	Therapeutic Target
NPT1674	CAMK2A	CaM kinase II alpha	Q9UQM7	CHEMBL4147	T18299	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT5106	PDE10A	Phosphodiesterase 10A	Q9Y233	CHEMBL4409	T84133	0	0	1	Enzyme	Phosphodiesterase	Phosphodiesterase 10	Phosphodiesterase 10	Therapeutic Target
NPT2546	AKT3	Serine/threonine-protein kinase AKT3	Q9Y243	CHEMBL4816	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT9	POLH	DNA polymerase eta	Q9Y253	CHEMBL5542	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT1149	PLAA	Phospholipase A-2-activating protein	Q9Y263	CHEMBL6114	NA	0	0	1	Unclassified protein	n.a.	n.a.	Unclassified protein	Therapeutic Target
NPT1144	CA5B	Carbonic anhydrase VB	Q9Y2D0	CHEMBL3969	NA	0	0	1	Enzyme	Lyase	n.a.	Lyase	Therapeutic Target
NPT3233	STK38L	Serine/threonine-protein kinase 38-like	Q9Y2H1	CHEMBL4851	T37417	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT1791	NISCH	Nischarin	Q9Y2I1	CHEMBL3923	T78943	0	0	1	Other cytosolic protein	n.a.	n.a.	Other cytosolic protein	Therapeutic Target
NPT3378	SIK3	Serine/threonine-protein kinase SIK3	Q9Y2K2	CHEMBL6149	T81830	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT4948	GSTK1	Glutathione S-transferase kappa 1	Q9Y2Q3	CHEMBL4491	NA	0	0	1	Enzyme	Transferase	n.a.	Transferase	Therapeutic Target
NPT4120	GPR55	G-protein coupled receptor 55	Q9Y2T6	CHEMBL1075322	T87670	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3413	MAP3K2	Mitogen-activated protein kinase kinase kinase 2	Q9Y2U5	CHEMBL5914	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT3274	DYRK1B	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Q9Y463	CHEMBL5543	T82720	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT864	L3MBTL1	Lethal(3)malignant brain tumor-like protein 1	Q9Y468	CHEMBL1287622	NA	0	0	1	Epigenetic regulator	Reader	Methyl-lysine/arginine binding protein	Methyl-lysine/arginine binding protein	Therapeutic Target
NPT2982	DAGLA	Sn1-specific diacylglycerol lipase alpha	Q9Y4D2	CHEMBL5545	T03150	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3109	MAP4K5	Mitogen-activated protein kinase kinase kinase kinase 5	Q9Y4K4	CHEMBL4852	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT987	HRH3	Histamine H3 receptor	Q9Y5N1	CHEMBL264	T64765	0	0	1	Membrane receptor	Family A G protein-coupled receptor	Small molecule receptor (family A GPCR)	Small molecule receptor (family A GPCR)	Therapeutic Target
NPT3330	CDC42BPB	Serine/threonine-protein kinase MRCK beta	Q9Y5S2	CHEMBL5052	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT6188	NOX1	NADPH oxidase 1	Q9Y5S8	CHEMBL1287628	NA	0	0	1	Transporter	Transmembrane 1-electron transfer carriers	n.a.	Transmembrane 1-electron transfer carriers	Therapeutic Target
NPT3066	LIPG	Endothelial lipase	Q9Y5X9	CHEMBL5080	T19368	0	0	1	Enzyme	Hydrolase	n.a.	Hydrolase	Therapeutic Target
NPT3332	STK24	Serine/threonine-protein kinase 24	Q9Y6E0	CHEMBL5082	NA	0	0	1	Enzyme	Kinase	Protein Kinase	Protein Kinase	Therapeutic Target
NPT73	SLCO1B1	Solute carrier organic anion transporter family member 1B1	Q9Y6L6	CHEMBL1697668	T46814	1	0	0	Transporter	Electrochemical transporter	SLC superfamily of solute carriers	SLC superfamily of solute carriers	Drug Transporter
NPT6327	NCOA3	Nuclear receptor coactivator 3	Q9Y6Q9	CHEMBL1615382	T26774	0	0	1	Epigenetic regulator	Writer	Histone acetyltransferase	Histone acetyltransferase	Therapeutic Target