ICD10 Disease Category |
Disease Name |
ICD10 Code |
Linked Targets |
N00-N99: Diseases of the genitourinary system |
Urinary dysfunction |
N39.3-N39.4 |
ACHE |
NA: NA |
Upper abdominal bloating |
NA |
ACHE |
H00-H59: Diseases of the eye and adnexa |
Open-angle glaucoma |
H40-H42 |
ACHE |
C00-D49: Neoplasms |
B-cell lymphoma |
C85.1 |
SYK |
NA: NA |
Anaplastic mixed oligoastrocytoma |
NA |
FLT3 |
K00-K95: Diseases of the digestive system |
Colon polyps |
K63.5 |
PTGS2 |
C00-D49: Neoplasms |
Colon cancer |
C50 |
FLT3 |
C00-D49: Neoplasms |
Colorectal cancer |
C18-C21 |
TP53; FLT3 |
C00-D49: Neoplasms |
Lymphoma |
C81-C86 |
HIF1A |
N00-N99: Diseases of the genitourinary system |
Vagina disease |
N76.0 |
ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Autoimmune diabetes |
E08-E13 |
SYK; ESR1 |
N00-N99: Diseases of the genitourinary system |
Atrophic vaginitis |
N95.2 |
ESR1 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Atrophy |
M62.571 |
ESR1 |
Z00-Z99: Factors influencing health status and contact with health services |
Contraception |
Z30 |
AR; ESR1 |
C00-D49: Neoplasms |
Leukemia |
C90-C95 |
FLT3; ESR1 |
C00-D49: Neoplasms |
Late-stage solid tumors |
C00-C75, C7A, C7B, D10-D36, D3A |
TP53 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Knee osteoarthritis |
M15-M19, M47 |
PTGS2 |
L00-L99: Diseases of the skin and subcutaneous tissue |
Vitiligo |
L80 |
MAOA |
E00-E89: Endocrine, nutritional and metabolic diseases |
Male hormonal deficiencies |
E20-E35 |
AR |
NA: NA |
Male hypogonadism |
NA |
AR |
C00-D49: Neoplasms |
Advanced breast cancer |
C50 |
CYP19A1 |
H00-H59: Diseases of the eye and adnexa |
Eye disorders |
H00-H59 |
ESR1 |
NA: NA |
Menopausal disorder |
NA |
ESR1 |
N00-N99: Diseases of the genitourinary system |
Female infertility |
N97.0 |
ESR1; ESR1 |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Female sexual dysfunction |
F52 |
ESR1 |
S00-T88: Injury, poisoning and certain other consequences of external causes |
Poison intoxication |
T36-T50 |
ACHE |
S00-T88: Injury, poisoning and certain other consequences of external causes |
Allergy |
T78.4 |
SYK |
L00-L99: Diseases of the skin and subcutaneous tissue |
Alopecia |
L65.9 |
AR |
G00-G99: Diseases of the nervous system G00-G99 |
Alzheimer disease |
G30 |
GSK3B; ACHE; ACHE; ACHE; MAOA; PTGS2; MAPT |
C00-D49: Neoplasms |
AML |
NA |
FLT3 |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Major depressive disorder |
F32, F33, M32 |
MAOA; MAOA |
NA: NA |
Postmenopausal disorder |
NA |
ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Female hypogonadism |
E23, E28 |
ESR1 |
N00-N99: Diseases of the genitourinary system |
Post-menopausal vaginal atrophy |
N95.2 |
ESR1 |
K00-K95: Diseases of the digestive system |
Alcoholic hepatitis |
K70.1 |
AR |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Alcohol use disorders |
F10.2 |
MAOA |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Mood disorder |
F30-F39 |
MAOA |
N00-N99: Diseases of the genitourinary system |
Prostate disease |
N42.9 |
CYP19A1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hypogonadism |
E23.0, E28.3, E29.1 |
AR; ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hyperuricemia |
E79.0 |
XDH |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hyperuricaemia in gout |
E79.0, M10 |
XDH |
C00-D49: Neoplasms |
Metastatic prostate cancer |
C61 |
AR |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Mild cognitive impairment |
F06.7 |
ACHE |
C00-D49: Neoplasms |
Osteosarcoma |
C40-C41 |
GSK3B |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Osteoporosis in post-menopausal women |
M80-M81 |
AR |
J00-J99: Diseases of the respiratory system |
Airway inflammation |
J00-J99 |
FLT3 |
I00-I99: Diseases of the circulatory system |
Thrombosis |
I80-I82 |
SYK |
C00-D49: Neoplasms |
Thyroid cancer |
C73 |
TSHR |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Ankylosing spondylitis |
M08.1, M45 |
PTGS2 |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Anxiety disorder |
F32, F40-F42 |
ACHE; CYP3A4; MAOA |
C00-D49: Neoplasms |
Metastatic castration-resistant prostate cancer |
C61 |
AR |
N00-N99: Diseases of the genitourinary system |
Menopause symptoms |
N95.0 |
ESR1; ESR1 |
N00-N99: Diseases of the genitourinary system |
Menorrhagia |
N92.0 |
ESR1 |
Z00-Z99: Factors influencing health status and contact with health services |
Oral contraceptive |
Z30 |
ESR1 |
C00-D49: Neoplasms |
Pancreatic cancer |
C25 |
FLT3; PTGS2 |
G00-G99: Diseases of the nervous system G00-G99 |
Parkinson's disease |
G20 |
ACHE; MAOA |
A00-B99: Certain infectious and parasitic diseases |
Pediculus humanus capitis |
B85.0 |
ACHE |
E00-E89: Endocrine, nutritional and metabolic diseases |
Amyloidosis |
E85 |
TTR |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Muscle atrophy |
M62.5 |
AR |
G00-G99: Diseases of the nervous system G00-G99 |
Multiple scierosis |
G35 |
ESR1; ESR1 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Moderate to severe rheumatoid arthritis |
M05-M06 |
PTGS2 |
Q00-Q99: Congenital malformations, deformations and chromosomal abnormalities |
Osteopetrosis |
Q78.2 |
ESR1 |
C00-D49: Neoplasms |
Oral cavity cancer |
C00-C08 |
TP53 |
J00-J99: Diseases of the respiratory system |
Asthma |
J45 |
SYK; SYK; PTGS2 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Arthritis |
M00-M25 |
PTGS2; PTGS2; ABCC1 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Arthralgia |
M25.5 |
ESR1 |
I00-I99: Diseases of the circulatory system |
Heart failure |
I50 |
AR; XDH |
H60-H95: Diseases of the ear and mastoid process |
Hearing disorder |
H90.5 |
TP53 |
W85-W99: Exposure to electric current, radiation and extreme ambient air temperature and pressure |
Diagnostic test to differentiate primary and secondary hypothyroidism |
W88 |
TSHR |
G00-G99: Diseases of the nervous system G00-G99 |
Neuropathic pain |
G64, G90.0 |
MAOA; PTGS2; PTGS2 |
I00-I99: Diseases of the circulatory system |
Neurological disease |
I21, I22, R52, R52.1-R52.2, R60.9, G89 |
ESR1 |
C00-D49: Neoplasms |
Hematological malignancies |
C81-C86 |
SYK; TP53 |
N00-N99: Diseases of the genitourinary system |
Dyspareunia |
N94.1 |
ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetic complication |
E08-E13 |
AKR1B1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetic neuropathy |
E11.40 |
AKR1B1 |
C00-D49: Neoplasms |
Non-hodgkin's lymphoma |
C85 |
SYK |
C00-D49: Neoplasms |
Carcinoma |
D00-D09 |
ESR1 |
C00-D49: Neoplasms |
Cancer |
C00-C96 |
AR; GSK3B; HIF1A; SYK; TP53; FLT3; FLT3; ACHE; ESR1; ESR1; PTGS2; CSNK2A1 |
N00-N99: Diseases of the genitourinary system |
Infertility |
N97.0 |
ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetes |
E23.2, N25.1 |
GSK3B; AKR1B1 |
L00-L99: Diseases of the skin and subcutaneous tissue |
Dermatological disease |
L00-L99 |
AR |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Depression |
F30-F39 |
MAOA |
A00-B99: Certain infectious and parasitic diseases |
Diarrhea |
A09, K59.1 |
CFTR |
G00-G99: Diseases of the nervous system G00-G99 |
Myasthenia gravis diagnosis |
G70.0 |
ACHE |
G00-G99: Diseases of the nervous system G00-G99 |
Myasthenia gravis |
G70.0 |
ACHE |
C00-D49: Neoplasms |
Myelofibrosis |
C94.4, D47.4 |
FLT3 |
C00-D49: Neoplasms |
Myeloid leukemia |
C92 |
FLT3 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Inflammation |
E08-E13, E10.2, E11, E11.2, E13.2, I73.9, I80-I82, N00-N29, G89 |
PTGS2 |
C00-D49: Neoplasms |
Inflammatory disease |
C11, C44, K75.9, M00-M25 |
SYK; PTGS2 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Osteoporosis |
M80-M81, Z79.890 |
AR; ESR1 |
L00-L99: Diseases of the skin and subcutaneous tissue |
Acne vulgaris |
L70.0 |
AR; AR; ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Cystic fibrosis |
E84 |
AR; CFTR |
R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified |
Cachexia |
R64 |
AR |
R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified |
Chronic pain |
R52.1-R52.2, G89 |
PTGS2 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Estrogen deficiency |
E28.39 |
ESR1 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Osteoarthritis |
M15-M19, M47 |
PTGS2; PTGS2; PTGS2; PTGS2; PTGS2; PTGS2 |
C00-D49: Neoplasms |
Castration-resistant prostate cancer |
C61 |
AR |
I00-I99: Diseases of the circulatory system |
Cardiomyopathy |
I42.0 |
TTR |
I00-I99: Diseases of the circulatory system |
Cardiovascular disorder |
I00-I99 |
AR |
S00-T88: Injury, poisoning and certain other consequences of external causes |
Poisoning due to pesticides and chemicals |
T36-T50 |
ACHE |
NA: NA |
GIST |
NA |
FLT3 |
H00-H59: Diseases of the eye and adnexa |
Glaucoma |
H40-H42 |
ACHE; AKR1B1 |
C00-D49: Neoplasms |
Glioblastoma |
NA |
FLT3 |
NA: NA |
Gonorrheal vaginitis |
NA |
ESR1 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Gout |
M10 |
XDH; AKR1B1; PTGS2; ABCC1; ABCC1 |
G00-G99: Diseases of the nervous system G00-G99 |
Epilepsy |
G40 |
MAOA |
G00-G99: Diseases of the nervous system G00-G99 |
Epileptic seizures |
G40, P90, R56 |
ACHE |
C00-D49: Neoplasms |
Bladder cancer |
C67 |
AR; CYP19A1 |
C00-D49: Neoplasms |
Adrenocortical carcinoma |
C74.0 |
ESR1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Endocrine disease |
E00-E35 |
AR |
G00-G99: Diseases of the nervous system G00-G99 |
Encephalopathy |
G93.4 |
XDH |
N00-N99: Diseases of the genitourinary system |
Endometriosis |
N80 |
CYP19A1; PTGS2 |
C00-D49: Neoplasms |
Solid tumours |
C00-D48 |
HIF1A; SYK; TP53; FLT3; PKM |
C00-D49: Neoplasms |
Brain cancer |
C71, D33 |
ESR1 |
C00-D49: Neoplasms |
Breast cancer |
C50 |
AR; CYP19A1; FLT3; FLT3; ESR1; ESR1 |
C00-D49: Neoplasms |
Non-small cell lung cancer |
C33-C34 |
PTGS2 |
C00-D49: Neoplasms |
Head and neck cancer |
C07-C14, C32-C33 |
TP53; AKR1B1 |
NA: NA |
Rheumatold arthritis |
NA |
PTGS2; PTGS2; PTGS2 |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Rheumatoid arthritis |
M05-M06 |
SYK; AKR1B1; PTGS2; PTGS2; PTGS2; PTGS2 |
N00-N99: Diseases of the genitourinary system |
Dysmenorrhea |
N94.4-N94.6 |
ESR1; PTGS2; PTGS2; PTGS2; PTGS2 |
NA: NA |
Early satiation associated with functional dyspepsia |
NA |
ACHE |
E00-E89: Endocrine, nutritional and metabolic diseases |
Testosterone deficiency |
E29.1 |
AR |
E00-E89: Endocrine, nutritional and metabolic diseases |
TTR amyloidosis |
E85 |
TTR |
G00-G99: Diseases of the nervous system G00-G99 |
Central nervous system disease |
G00-G99 |
MAPT |
C00-D49: Neoplasms |
Chronic lymphocytic leukaemia |
C91 |
SYK |
K00-K95: Diseases of the digestive system |
Xerostomia |
K11.7, R68.2 |
ACHE |
A00-B99: Certain infectious and parasitic diseases |
Helminth infection |
A00-B99 |
ACHE |
NA: NA |
Hematopoietic stem cell transplantation |
NA |
FLT3 |
I00-I99: Diseases of the circulatory system |
Renal artery disease |
I70.1 |
TP53 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetic cataract |
E10.36, E11.36 |
AKR1B1 |
C00-D49: Neoplasms |
Female androgenresponsive recurrent mammary cancer |
C50 |
AR |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Cognitive disorders |
F01-F07, F04, F05, R41.3 |
ACHE; MAPT |
C00-D49: Neoplasms |
Hormonally-responsive breast cancer |
C50 |
CYP19A1 |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hormone deficiency |
E00-E90 |
AR; ESR1; ESR1 |
A00-B99: Certain infectious and parasitic diseases |
HIV-associated diarrhoea |
A09 |
CFTR |
C00-D49: Neoplasms |
Refractory renal cell carcinoma |
C64 |
PKM |
N00-N99: Diseases of the genitourinary system |
Female infertility due to anovulation |
N97.0 |
ESR1 |
C00-D49: Neoplasms |
Advanced prostate cancer |
C61 |
AR; ESR1 |
C00-D49: Neoplasms |
Gliosarcoma |
NA |
FLT3 |
A00-B99: Certain infectious and parasitic diseases |
Human immunodeficiency virus infection |
B20-B26 |
FLT3 |
Z00-Z99: Factors influencing health status and contact with health services |
Hormone replacement therapy |
Z79.890 |
ESR1 |
I00-I99: Diseases of the circulatory system |
Pulmonary arterial hypertension |
I27.0, I27.2 |
HIF1A |
C00-D49: Neoplasms |
CLL |
NA |
FLT3 |
A00-B99: Certain infectious and parasitic diseases |
Trematode infection |
B66.9 |
ESR1 |
H00-H59: Diseases of the eye and adnexa |
Chronic glaucoma |
H40-H42 |
ACHE |
G00-G99: Diseases of the nervous system G00-G99 |
Pain |
G64, G90.0, R52, G89 |
AR; ACHE; ESR1; PTGS2; PTGS2; PTGS2; PTGS2; PKM |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hyperlipidaemia |
E78 |
ESR1 |
S00-T88: Injury, poisoning and certain other consequences of external causes |
Hyperthermia |
T68 |
PTGS2 |
L00-L99: Diseases of the skin and subcutaneous tissue |
Psoriasis |
L40 |
FLT3 |
N00-N99: Diseases of the genitourinary system |
Prostate hyperplasia |
N40 |
AR |
C00-D49: Neoplasms |
Prostate cancer |
C61 |
AR; AR; FLT3; ESR1 |
NA: NA |
Joint and muscular pain |
NA |
PTGS2 |
N00-N99: Diseases of the genitourinary system |
Irregularities |
N92.6 |
ESR1 |
S00-T88: Injury, poisoning and certain other consequences of external causes |
Toxicity |
T36-T50, T51-T65 |
TP53 |
C00-D49: Neoplasms |
Thyroid cancer diagnosis |
C73 |
TSHR |
E00-E89: Endocrine, nutritional and metabolic diseases |
Type 2 diabetes |
E11 |
PTGS2 |
C00-D49: Neoplasms |
Hormone refractory prostate cancer |
C61 |
AR; ESR1 |
C00-D49: Neoplasms |
Acute lymphoblastic leukemia |
C91.0 |
FLT3 |
C00-D49: Neoplasms |
Acute myeloid leukemia |
C92.0 |
TP53; TP53; FLT3; FLT3 |
G00-G99: Diseases of the nervous system G00-G99 |
Neurodegenerative disease |
G30-G32 |
ACHE; MAPT |
K00-K95: Diseases of the digestive system |
Inflammatory bowel disease |
K50, K51 |
PTGS2 |