Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Unclassified | PAX8 | Paired box protein Pax-8 | Q06710 | CHEMBL2362980 |
Unclassified | HTT | Huntingtin | P42858 | CHEMBL5514 |
Unclassified | RAB9A | Ras-related protein Rab-9A | P51151 | CHEMBL1293294 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
CC | GO:0044464; cell part | GO:0005770; late endosome | 1.448E-04 | 3.979E-01 | HTT, RAB9A |
MF | GO:0060089; molecular transducer activity | GO:0004996; thyroid-stimulating hormone receptor activity | 3.106E-04 | 3.979E-01 | PAX8 |
MF | GO:0005488; binding | GO:0034452; dynactin binding | 1.708E-03 | 5.237E-01 | HTT |
MF | GO:0005215; transporter activity | GO:0005319; lipid transporter activity | 2.220E-02 | 1.000E+00 | HTT |
MF | GO:0005488; binding | GO:0001047; core promoter binding | 2.587E-02 | 1.000E+00 | PAX8 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09160 Human Diseases | 09161 Cancers | hsa05216 | Thyroid cancer | 4.344E-03 | 2.606E-02 | PAX8 |
09150 Organismal Systems | 09152 Endocrine system | hsa04918 | Thyroid hormone synthesis | 1.061E-02 | 3.184E-02 | PAX8 |
09160 Human Diseases | 09167 Infectious diseases | hsa05162 | Measles | 2.026E-02 | 3.441E-02 | RAB9A |
09160 Human Diseases | 09163 Neurodegenerative diseases | hsa05016 | Huntington's disease | 2.867E-02 | 3.441E-02 | HTT |
09160 Human Diseases | 09161 Cancers | hsa05202 | Transcriptional misregulation in cancer | 2.676E-02 | 3.441E-02 | PAX8 |
09160 Human Diseases | 09161 Cancers | hsa05200 | Pathways in cancer | 5.838E-02 | 5.838E-02 | PAX8 |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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