Plant ID: NPO12620
Plant Latin Name: Carum carvi
Taxonomy Genus: Carum
Taxonomy Family: Apiaceae
NCBI TaxonomyDB:
48032
Plant-of-the-World-Online:
n.a.
Antiseptic; Antispasmodic; Aromatic; Carminative; Digestive; Emmenagogue; Expectorant; Galactogogue; Ophthalmic; Parasiticide; Stimulant
Lebanon; India; Jordan; Thailand; China; Iraq; Bulgaria
CDA; | |
SLC28A1; SLC28A3; | |
LMNA; |
Cytochrome P450 Enzymes: |
---|
Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Enzyme_unclassified | CDA | Cytidine deaminase | P32320 | CHEMBL4502 |
SLC superfamily of solute carriers | SLC28A1 | Sodium/nucleoside cotransporter 1 | O00337 | CHEMBL5551 |
SLC superfamily of solute carriers | SLC28A3 | Solute carrier family 28 member 3 | Q9HAS3 | CHEMBL5707 |
Unclassified | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
BP | GO:0051179; localization | GO:1904823; purine nucleobase transmembrane transport | 9.649E-08 | 4.202E-04 | SLC28A1, SLC28A3 |
BP | GO:0051179; localization | GO:0015855; pyrimidine nucleobase transport | 9.649E-08 | 4.202E-04 | SLC28A1, SLC28A3 |
MF | GO:0005215; transporter activity | GO:0015389; pyrimidine- and adenine-specific:sodium symporter activity | 3.216E-08 | 4.202E-04 | SLC28A1, SLC28A3 |
BP | GO:0051179; localization | GO:1901642; nucleoside transmembrane transport | 6.752E-07 | 1.470E-03 | SLC28A1, SLC28A3 |
BP | GO:0051179; localization | GO:0072531; pyrimidine-containing compound transmembrane transport | 1.447E-06 | 2.250E-03 | SLC28A1, SLC28A3 |
CC | GO:0044425; membrane part | GO:0005887; integral component of plasma membrane | 2.889E-02 | 1.000E+00 | SLC28A1, SLC28A3 |
CC | GO:0044464; cell part | GO:0005635; nuclear envelope | 3.333E-02 | 1.000E+00 | LMNA |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00983 | Drug metabolism - other enzymes | 9.169E-03 | 2.917E-02 | CDA |
09160 Human Diseases | 09165 Cardiovascular diseases | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 1.472E-02 | 2.917E-02 | LMNA |
09160 Human Diseases | 09165 Cardiovascular diseases | hsa05410 | Hypertrophic cardiomyopathy (HCM) | 1.650E-02 | 2.917E-02 | LMNA |
09160 Human Diseases | 09165 Cardiovascular diseases | hsa05414 | Dilated cardiomyopathy | 1.788E-02 | 2.917E-02 | LMNA |
09140 Cellular Processes | 09143 Cell growth and death | hsa04210 | Apoptosis | 2.771E-02 | 3.233E-02 | LMNA |
09100 Metabolism | 09104 Nucleotide metabolism | hsa00240 | Pyrimidine metabolism | 2.084E-02 | 2.917E-02 | CDA |
Unclassified | Unclassified | hsa01100 | Metabolic pathways | 2.257E-01 | 2.257E-01 | CDA |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
---|---|---|---|
C00-D49: Neoplasms | Solid tumours | C00-D48 | CDA; |