Target_ID Gene_Symbol Protein_Name Uniprot_ID ChEMBL_ID TTD_ID Target_Class_Level1 Target_Class_Level2 Target_Class_Level3 NPT10 GMNN Geminin O75496 CHEMBL1293278 T57387 NPT1008 GABRR1 GABA receptor rho-1 subunit P24046 CHEMBL3561 T99665 Ion channel Ligand-gated ion channel GABA-A receptor NPT102 CXCL8 Interleukin-8 P10145 CHEMBL2157 T22658 NPT103 RORC Nuclear receptor ROR-gamma P51449 CHEMBL1741186 T25307 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group F NPT1038 KMT2A Histone-lysine N-methyltransferase MLL Q03164 CHEMBL1293299 T25462 Epigenetic regulator Reader Plant homeodomain NPT1044 TOP2A DNA topoisomerase II alpha P11388 CHEMBL1806 T17048 Enzyme Isomerase NPT106 PPARD Peroxisome proliferator-activated receptor delta Q03181 CHEMBL3979 T36557 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group C NPT1062 CA4 Carbonic anhydrase IV P22748 CHEMBL3729 T53378 Enzyme Lyase NPT1063 CA6 Carbonic anhydrase VI P23280 CHEMBL3025 T06569 Enzyme Lyase NPT107 NMUR2 Neuromedin-U receptor 2 Q9GZQ4 CHEMBL1075144 T04210 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1078 IDO1 Indoleamine 2,3-dioxygenase P14902 CHEMBL4685 T89697 Enzyme NPT1079 EP300 Histone acetyltransferase p300 Q09472 CHEMBL3784 T25956 Epigenetic regulator Reader Bromodomain NPT108 ESR1 Estrogen receptor alpha P03372 CHEMBL206 T89534 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group A NPT1080 KAT2B Histone acetyltransferase PCAF Q92831 CHEMBL5500 T16902 Epigenetic regulator Reader Bromodomain NPT1089 MMP12 Matrix metalloproteinase 12 P39900 CHEMBL4393 T03500 Enzyme Protease Metallo protease NPT109 CYP3A4 Cytochrome P450 3A4 P08684 CHEMBL340 T90391 Enzyme Cytochrome P450 Cytochrome P450 family 3 NPT1090 MMP13 Matrix metalloproteinase 13 P45452 CHEMBL280 T34296 Enzyme Protease Metallo protease NPT1099 SMO Smoothened homolog Q99835 CHEMBL5971 Membrane receptor Frizzled family G protein-coupled receptor Smoothened receptor (frizzled family GPCR) NPT110 CYP2D6 Cytochrome P450 2D6 P10635 CHEMBL289 T57392 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT1109 APLNR Apelin receptor P35414 CHEMBL1628481 T65783 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1110 CCR6 C-C chemokine receptor type 6 P51684 CHEMBL4423 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1111 CXCR5 C-X-C chemokine receptor type 5 P32302 CHEMBL1075315 T09528 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1119 ALOX12 Arachidonate 12-lipoxygenase P18054 CHEMBL3687 T35527 Enzyme NPT1133 MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Q9UKM7 CHEMBL2308 Enzyme NPT1137 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 P28845 CHEMBL4235 T65200 Enzyme NPT1138 HSD11B2 11-beta-hydroxysteroid dehydrogenase 2 P80365 CHEMBL3746 T43721 Enzyme NPT1143 CA5A Carbonic anhydrase VA P35218 CHEMBL4789 Enzyme Lyase NPT1144 CA5B Carbonic anhydrase VB Q9Y2D0 CHEMBL3969 Enzyme Lyase NPT1146 CA3 Carbonic anhydrase III P07451 CHEMBL2885 Enzyme Lyase NPT1196 ACP1 Low molecular weight phosphotyrosine protein phosphatase P24666 CHEMBL4903 Enzyme Phosphatase Protein Phosphatase NPT1197 HTT Huntingtin P42858 CHEMBL5514 T22496 NPT1210 PTPN2 T-cell protein-tyrosine phosphatase P17706 CHEMBL3807 Enzyme Phosphatase Protein Phosphatase NPT1211 DUSP3 Dual specificity protein phosphatase 3 P51452 CHEMBL2635 Enzyme Phosphatase Protein Phosphatase NPT1214 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 P35610 CHEMBL2782 Enzyme NPT1224 GAPDH Glyceraldehyde-3-phosphate dehydrogenase liver P04406 CHEMBL2284 T39321 Enzyme NPT1226 CASP7 Caspase-7 P55210 CHEMBL3468 T72252 Enzyme Protease Cysteine protease NPT1250 MIF Macrophage migration inhibitory factor P14174 CHEMBL2085 T78393 Enzyme NPT1255 SENP8 Sentrin-specific protease 8 Q96LD8 CHEMBL1741207 T13928 Enzyme NPT1256 SENP7 Sentrin-specific protease 7 Q9BQF6 CHEMBL1741213 Enzyme NPT1257 SENP6 Sentrin-specific protease 6 Q9GZR1 CHEMBL1741215 Enzyme NPT1259 GRM1 Metabotropic glutamate receptor 1 Q13255 CHEMBL3772 T27137 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT1265 PIM1 Serine/threonine-protein kinase PIM1 P11309 CHEMBL2147 T50594 Enzyme Kinase Protein Kinase NPT1270 AKR1B10 Aldo-keto reductase family 1 member B10 O60218 CHEMBL5983 Enzyme NPT1274 RAD52 DNA repair protein RAD52 homolog P43351 CHEMBL2362978 NPT1282 MITF Microphthalmia-associated transcription factor O75030 CHEMBL1741165 NPT1283 PAX8 Paired box protein Pax-8 Q06710 CHEMBL2362980 NPT1287 CNR2 Cannabinoid CB2 receptor P34972 CHEMBL253 T37693 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1289 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase P00492 CHEMBL2360 Enzyme NPT1291 PNP Purine nucleoside phosphorylase P00491 CHEMBL4338 T78198 Enzyme NPT13 LCK Tyrosine-protein kinase LCK P06239 CHEMBL258 T12499 Enzyme Kinase Protein Kinase NPT1324 GABRR2 GABA receptor rho-2 subunit P28476 CHEMBL2375 T90682 Ion channel Ligand-gated ion channel GABA-A receptor NPT1336 PGD 6-phosphogluconate dehydrogenase P52209 CHEMBL3404 T76497 Enzyme NPT1337 MET Hepatocyte growth factor receptor P08581 CHEMBL3717 T40474 Enzyme Kinase Protein Kinase NPT1356 P4HB Protein disulfide-isomerase P07237 CHEMBL5422 Enzyme NPT1371 CDK2 Cyclin-dependent kinase 2 P24941 CHEMBL301 T70176 Enzyme Kinase Protein Kinase NPT1391 P2RY6 Pyrimidinergic receptor P2Y6 Q15077 CHEMBL4714 T90782 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT14 FYN Tyrosine-protein kinase FYN P06241 CHEMBL1841 T17980 Enzyme Kinase Protein Kinase NPT1407 GABBR1 GABA-B receptor 1 Q9UBS5 CHEMBL2064 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT1416 NPSR1 Neuropeptide S receptor Q6W5P4 CHEMBL5162 T20958 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1418 FAAH Anandamide amidohydrolase O00519 CHEMBL2243 T11754 Enzyme NPT142 FABP4 Fatty acid binding protein adipocyte P15090 CHEMBL2083 T07217 NPT1422 ABCG2 ATP-binding cassette sub-family G member 2 Q9UNQ0 CHEMBL5393 Transporter Primary active transporter ATP-binding cassette NPT1423 CDK1 Cyclin-dependent kinase 1 P06493 CHEMBL308 T49898 Enzyme Kinase Protein Kinase NPT1426 MAPK8 c-Jun N-terminal kinase 1 P45983 CHEMBL2276 T40097 Enzyme Kinase Protein Kinase NPT1427 MAPK9 c-Jun N-terminal kinase 2 P45984 CHEMBL4179 T69375 Enzyme Kinase Protein Kinase NPT143 TOP1 DNA topoisomerase I P11387 CHEMBL1781 T09826 Enzyme Isomerase NPT1432 AURKA Serine/threonine-protein kinase Aurora-A O14965 CHEMBL4722 T87675 Enzyme Kinase Protein Kinase NPT1433 AURKB Serine/threonine-protein kinase Aurora-B Q96GD4 CHEMBL2185 T77764 Enzyme Kinase Protein Kinase NPT1434 BRAF Serine/threonine-protein kinase B-raf P15056 CHEMBL5145 T99089 Enzyme Kinase Protein Kinase NPT1435 ERBB4 Receptor protein-tyrosine kinase erbB-4 Q15303 CHEMBL3009 T92057 Enzyme Kinase Protein Kinase NPT1436 PTK2 Focal adhesion kinase 1 Q05397 CHEMBL2695 T15068 Enzyme Kinase Protein Kinase NPT1437 FES Tyrosine-protein kinase FES P07332 CHEMBL5455 T29083 Enzyme Kinase Protein Kinase NPT1438 IGF1R Insulin-like growth factor I receptor P08069 CHEMBL1957 T64977 Enzyme Kinase Protein Kinase NPT144 TERT Telomerase reverse transcriptase O14746 CHEMBL2916 T86052 Enzyme NPT1440 JAK3 Tyrosine-protein kinase JAK3 P52333 CHEMBL2148 Enzyme Kinase Protein Kinase NPT1441 MAPKAPK2 MAP kinase-activated protein kinase 2 P49137 CHEMBL2208 T21307 Enzyme Kinase Protein Kinase NPT1444 PIK3CA PI3-kinase p110-alpha subunit P42336 CHEMBL4005 T80276 Enzyme NPT1445 PIK3CG PI3-kinase p110-gamma subunit P48736 CHEMBL3267 T95913 Enzyme NPT1449 SYK Tyrosine-protein kinase SYK P43405 CHEMBL2599 T62431 Enzyme Kinase Protein Kinase NPT145 OPRM1 Mu opioid receptor P35372 CHEMBL233 T47768 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT1463 CYP2J2 Cytochrome P450 2J2 P51589 CHEMBL3491 Enzyme NPT1464 PDE4D Phosphodiesterase 4D Q08499 CHEMBL288 T47941 Enzyme Phosphodiesterase Phosphodiesterase 4 NPT1478 KDR Vascular endothelial growth factor receptor 2 P35968 CHEMBL279 T80975 Enzyme Kinase Protein Kinase NPT1479 KIT Stem cell growth factor receptor P10721 CHEMBL1936 T57700 Enzyme Kinase Protein Kinase NPT1480 FGFR1 Fibroblast growth factor receptor 1 P11362 CHEMBL3650 T47101 Enzyme Kinase Protein Kinase NPT149 HSD17B10 Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Q99714 CHEMBL4159 Enzyme NPT151 HPGD 15-hydroxyprostaglandin dehydrogenase [NAD+] P15428 CHEMBL1293255 Enzyme NPT1518 SLC1A1 Excitatory amino acid transporter 3 P43005 CHEMBL2721 T31721 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT1519 SLC1A2 Excitatory amino acid transporter 2 P43004 CHEMBL4973 T95438 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT152 NFE2L2 Nuclear factor erythroid 2-related factor 2 Q16236 CHEMBL1075094 T88505 NPT1529 PNMT Phenylethanolamine N-methyltransferase P11086 CHEMBL4617 T56496 Enzyme NPT153 AR Androgen Receptor P10275 CHEMBL1871 T46521 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C NPT154 SMAD3 Mothers against decapentaplegic homolog 3 P84022 CHEMBL1293258 NPT1540 SLC22A2 Solute carrier family 22 member 2 O15244 CHEMBL1743122 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT1546 SLC22A3 Solute carrier family 22 member 3 O75751 CHEMBL2073673 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT1547 CTSD Cathepsin D P07339 CHEMBL2581 T67102 Enzyme Protease Aspartic protease NPT155 AHR Aryl hydrocarbon receptor P35869 CHEMBL3201 T23666 NPT1566 GLO1 Glyoxalase I Q04760 CHEMBL2424 T88285 Enzyme NPT1569 CTRC Chymotrypsin C Q99895 CHEMBL2386 T10118 Enzyme Protease Serine protease NPT157 BRCA1 Breast cancer type 1 susceptibility protein P38398 CHEMBL5990 Enzyme NPT1571 CDK6 Cyclin-dependent kinase 6 Q00534 CHEMBL2508 Enzyme Kinase Protein Kinase NPT1575 PIK3R1 PI3-kinase p85-alpha subunit P27986 CHEMBL2506 Enzyme NPT1580 AMY1A;AMY1B;AMY1C Salivary alpha-amylase P04745 CHEMBL2478 Enzyme NPT1581 CBR1 Carbonyl reductase [NADPH] 1 P16152 CHEMBL5586 T70518 Enzyme NPT1583 HSF1 Heat shock factor protein 1 Q00613 CHEMBL5869 T49639 NPT1587 HSD17B1 Estradiol 17-beta-dehydrogenase 1 P14061 CHEMBL3181 T44011 Enzyme NPT1588 HSD17B2 Estradiol 17-beta-dehydrogenase 2 P37059 CHEMBL2789 Enzyme NPT1591 PREP Prolyl endopeptidase P48147 CHEMBL3202 T86161 Enzyme Protease Serine protease NPT1592 DPP4 Dipeptidyl peptidase IV P27487 CHEMBL284 T31391 Enzyme Protease Serine protease NPT1594 ABCC1 Multidrug resistance-associated protein 1 P33527 CHEMBL3004 T11288 Transporter Primary active transporter ATP-binding cassette NPT1598 CSNK2A1 Casein kinase II alpha P68400 CHEMBL3629 T51565 Enzyme Kinase Protein Kinase NPT1603 CYP1A1 Cytochrome P450 1A1 P04798 CHEMBL2231 Enzyme Cytochrome P450 Cytochrome P450 family 1 NPT1604 CYP1B1 Cytochrome P450 1B1 Q16678 CHEMBL4878 T92521 Enzyme Cytochrome P450 Cytochrome P450 family 1 NPT1606 NOX4 NADPH oxidase 4 Q9NPH5 CHEMBL1250375 T29741 Enzyme NPT1608 CHEK1 Serine/threonine-protein kinase Chk1 O14757 CHEMBL4630 T62449 Enzyme Kinase Protein Kinase NPT1611 RPS6KB1 Ribosomal protein S6 kinase 1 P23443 CHEMBL4501 T94479 Enzyme Kinase Protein Kinase NPT1612 MAPKAPK5 MAP kinase-activated protein kinase 5 Q8IW41 CHEMBL3094 T29754 Enzyme Kinase Protein Kinase NPT1616 MAPK11 MAP kinase p38 beta Q15759 CHEMBL3961 T55729 Enzyme Kinase Protein Kinase NPT1619 GALK1 Galactokinase P51570 CHEMBL1293257 Enzyme NPT1620 STAT6 Signal transducer and activator of transcription 6 P42226 CHEMBL5401 T20585 NPT1627 GPR35 G-protein coupled receptor 35 Q9HC97 CHEMBL1293267 T56143 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT163 NFKB1 Nuclear factor NF-kappa-B p105 subunit P19838 CHEMBL3251 T40192 NPT1630 CAMK2B CaM kinase II beta Q13554 CHEMBL4121 T18299 Enzyme Kinase Protein Kinase NPT1634 MPO Myeloperoxidase P05164 CHEMBL2439 T23471 Enzyme NPT1650 FLT3 Tyrosine-protein kinase receptor FLT3 P36888 CHEMBL1974 T74312 Enzyme Kinase Protein Kinase NPT1656 PKN1 Protein kinase N1 Q16512 CHEMBL3384 T60003 Enzyme Kinase Protein Kinase NPT1657 NEK6 Serine/threonine-protein kinase NEK6 Q9HC98 CHEMBL4309 T30829 Enzyme Kinase Protein Kinase NPT1658 NEK2 Serine/threonine-protein kinase NEK2 P51955 CHEMBL3835 T49102 Enzyme Kinase Protein Kinase NPT1659 AXL Tyrosine-protein kinase receptor UFO P30530 CHEMBL4895 T82383 Enzyme Kinase Protein Kinase NPT166 CES1 Acyl coenzyme A:cholesterol acyltransferase P23141 CHEMBL2265 T76369 Enzyme NPT1660 NUAK1 NUAK family SNF1-like kinase 1 O60285 CHEMBL5784 T21653 Enzyme Kinase Protein Kinase NPT1661 ALK ALK tyrosine kinase receptor Q9UM73 CHEMBL4247 Enzyme Kinase Protein Kinase NPT1667 PYGL Liver glycogen phosphorylase P06737 CHEMBL2568 Enzyme NPT1670 MPG DNA-3-methyladenine glycosylase P29372 CHEMBL3396943 NPT1672 CAMK1D CaM kinase I delta Q8IU85 CHEMBL5073 Enzyme Kinase Protein Kinase NPT1674 CAMK2A CaM kinase II alpha Q9UQM7 CHEMBL4147 T18299 Enzyme Kinase Protein Kinase NPT1675 CAMK2D CaM kinase II delta Q13557 CHEMBL2801 T18299 Enzyme Kinase Protein Kinase NPT1676 CAMK2G CaM kinase II gamma Q13555 CHEMBL3829 T18299 Enzyme Kinase Protein Kinase NPT1678 CAMKK2 CaM-kinase kinase beta Q96RR4 CHEMBL5284 T82262 Enzyme Kinase Protein Kinase NPT1680 CHEK2 Serine/threonine-protein kinase Chk2 O96017 CHEMBL2527 T28713 Enzyme Kinase Protein Kinase NPT1681 CLK1 Dual specificty protein kinase CLK1 P49759 CHEMBL4224 T46685 Enzyme Kinase Protein Kinase NPT1682 CLK2 Dual specificity protein kinase CLK2 P49760 CHEMBL4225 T73725 Enzyme Kinase Protein Kinase NPT1685 CSNK1G2 Casein kinase I gamma 2 P78368 CHEMBL2543 T82773 Enzyme Kinase Protein Kinase NPT1686 CSNK1G3 Casein kinase I isoform gamma-3 Q9Y6M4 CHEMBL5084 T29728 Enzyme Kinase Protein Kinase NPT1687 DAPK3 Death-associated protein kinase 3 O43293 CHEMBL2468 T81623 Enzyme Kinase Protein Kinase NPT1699 PDPK1 3-phosphoinositide dependent protein kinase-1 O15530 CHEMBL2534 T20891 Enzyme Kinase Protein Kinase NPT1700 PIM2 Serine/threonine-protein kinase PIM2 Q9P1W9 CHEMBL4523 T07279 Enzyme Kinase Protein Kinase NPT1701 PIM3 Serine/threonine-protein kinase PIM3 Q86V86 CHEMBL5407 T16596 Enzyme Kinase Protein Kinase NPT1702 PLK4 Serine/threonine-protein kinase PLK4 O00444 CHEMBL3788 T71374 Enzyme Kinase Protein Kinase NPT1703 PRKACA cAMP-dependent protein kinase alpha-catalytic subunit P17612 CHEMBL4101 T20669 Enzyme Kinase Protein Kinase NPT1705 RPS6KA3 Ribosomal protein S6 kinase alpha 3 P51812 CHEMBL2345 T03279 Enzyme Kinase Protein Kinase NPT1706 SLK Serine/threonine-protein kinase 2 Q9H2G2 CHEMBL4202 T57307 Enzyme Kinase Protein Kinase NPT1709 STK17A Serine/threonine-protein kinase 17A Q9UEE5 CHEMBL4525 T91323 Enzyme Kinase Protein Kinase NPT1713 PBK PDZ-binding kinase Q96KB5 CHEMBL4896 T98642 Enzyme Kinase Protein Kinase NPT1720 PLG Plasminogen P00747 CHEMBL1801 T89034 Enzyme Protease Serine protease NPT1721 DAPK1 Death-associated protein kinase 1 P53355 CHEMBL2558 Enzyme Kinase Protein Kinase NPT1746 NR1H2 LXR-beta P55055 CHEMBL4093 T13714 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group H NPT1755 TK1 Thymidine kinase, cytosolic P04183 CHEMBL2883 T30081 Enzyme NPT178 PTPN1 Protein-tyrosine phosphatase 1B P18031 CHEMBL335 T89529 Enzyme Phosphatase Protein Phosphatase NPT1784 HTR5A Serotonin 5a (5-HT5a) receptor P47898 CHEMBL3426 T15571 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1785 HTR7 Serotonin 7 (5-HT7) receptor P34969 CHEMBL3155 T79062 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1788 ADRA1A Alpha-1a adrenergic receptor P35348 CHEMBL229 T92609 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1789 ADRA1B Alpha-1b adrenergic receptor P35368 CHEMBL232 T29500 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1791 NISCH Nischarin Q9Y2I1 CHEMBL3923 T65689 NPT1794 NR1H3 LXR-alpha Q13133 CHEMBL2808 T52297 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group H NPT1811 DRD5 Dopamine D5 receptor P21918 CHEMBL1850 T46828 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT1814 GCGR Glucagon receptor P47871 CHEMBL1985 T87875 Membrane receptor Family B G protein-coupled receptor Peptide receptor (family B GPCR) NPT182 PRKCA Protein kinase C alpha P17252 CHEMBL299 T56722 Enzyme Kinase Protein Kinase NPT1834 CREBBP CREB-binding protein Q92793 CHEMBL5747 T03634 Epigenetic regulator Reader Bromodomain NPT1870 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) P10586 CHEMBL3521 Enzyme Phosphatase Protein Phosphatase NPT1890 ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 O75460 CHEMBL1163101 T01003 Enzyme NPT1896 GLI1 Zinc finger protein GLI1 P08151 CHEMBL5461 T40890 NPT1898 SHH Sonic hedgehog protein Q15465 CHEMBL5602 T12075 NPT198 VDR Vitamin D receptor P11473 CHEMBL1977 T34234 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group I NPT203 CES2 Carboxylesterase 2 O00748 CHEMBL3180 Enzyme NPT204 ACHE Acetylcholinesterase P22303 CHEMBL220 T30082 Enzyme Hydrolase NPT205 PTPN6 Protein-tyrosine phosphatase 1C P29350 CHEMBL3166 T98264 Enzyme Phosphatase Protein Phosphatase NPT206 PTPN11 Protein-tyrosine phosphatase 2C Q06124 CHEMBL3864 T13057 Enzyme Phosphatase Protein Phosphatase NPT208 CYP1A2 Cytochrome P450 1A2 P05177 CHEMBL3356 Enzyme Cytochrome P450 Cytochrome P450 family 1 NPT210 TSHR Thyroid stimulating hormone receptor P16473 CHEMBL1963 T60606 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT211 HIF1A Hypoxia-inducible factor 1 alpha Q16665 CHEMBL4261 T55610 NPT212 CYP2C9 Cytochrome P450 2C9 P11712 CHEMBL3397 T19244 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT213 CYP2C19 Cytochrome P450 2C19 P33261 CHEMBL3622 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT214 CTSB Cathepsin B P07858 CHEMBL4072 T61746 Enzyme Protease Cysteine protease NPT216 ADORA1 Adenosine A1 receptor P30542 CHEMBL226 T92072 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT217 ADORA2A Adenosine A2a receptor P29274 CHEMBL251 T77365 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT218 ADORA3 Adenosine A3 receptor P0DMS8 CHEMBL256 T36059 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT221 ADRA1D Alpha-1d adrenergic receptor P25100 CHEMBL223 T53381 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2213 CDK4 Cyclin-dependent kinase 4 P11802 CHEMBL331 T85799 Enzyme Kinase Protein Kinase NPT2215 POLA1 DNA polymerase alpha subunit P09884 CHEMBL1828 T26463 Enzyme Transferase NPT222 ADRA2A Alpha-2a adrenergic receptor P08913 CHEMBL1867 T11448 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2222 NPC1L1 Niemann-Pick C1-like protein 1 Q9UHC9 CHEMBL2027 NPT223 ADRA2B Alpha-2b adrenergic receptor P18089 CHEMBL1942 T41580 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT224 ADRA2C Alpha-2c adrenergic receptor P18825 CHEMBL1916 T01777 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT225 ADRB1 Beta-1 adrenergic receptor P08588 CHEMBL213 T44068 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT226 ADRB2 Beta-2 adrenergic receptor P07550 CHEMBL210 T52522 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2266 FBP1 Fructose-1,6-bisphosphatase P09467 CHEMBL3975 Enzyme NPT227 ADRB3 Beta-3 adrenergic receptor P13945 CHEMBL246 T51408 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT228 SLC6A2 Norepinephrine transporter P23975 CHEMBL222 T21945 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT232 CNR1 Cannabinoid CB1 receptor P21554 CHEMBL218 T76685 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT233 CA2 Carbonic anhydrase II P00918 CHEMBL205 T20401 Enzyme Lyase NPT234 CCR2 C-C chemokine receptor type 2 P41597 CHEMBL4015 T89988 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT237 CXCR1 Interleukin-8 receptor A P25024 CHEMBL4029 T00884 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT240 CYP2A6 Cytochrome P450 2A6 P11509 CHEMBL5282 T06455 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT242 DRD1 Dopamine D1 receptor P21728 CHEMBL2056 T22118 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT243 DRD2 Dopamine D2 receptor P14416 CHEMBL217 T67162 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT244 DRD3 Dopamine D3 receptor P35462 CHEMBL234 T02551 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT245 DRD4 Dopamine D4 receptor P21917 CHEMBL219 T24983 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT246 SLC6A3 Dopamine transporter Q01959 CHEMBL238 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT248 ESR2 Estrogen receptor beta Q92731 CHEMBL242 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group A NPT249 NR3C1 Glucocorticoid receptor P04150 CHEMBL2034 T40016 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C NPT251 HRH1 Histamine H1 receptor P35367 CHEMBL231 T77913 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT252 HRH2 Histamine H2 receptor P25021 CHEMBL1941 T30985 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2520 LTA4H Leukotriene A4 hydrolase P09960 CHEMBL4618 T03691 Enzyme Protease Metallo protease NPT253 HMGCR HMG-CoA reductase P04035 CHEMBL402 T53585 Enzyme Oxidoreductase NPT2533 F10 Coagulation factor X P00742 CHEMBL244 T84631 Enzyme Protease Serine protease NPT2536 ITGAL Leukocyte adhesion glycoprotein LFA-1 alpha P20701 CHEMBL1803 T35640 NPT2553 ANPEP Aminopeptidase N P15144 CHEMBL1907 T67272 Enzyme Protease Metallo protease NPT2562 PARP1 Poly [ADP-ribose] polymerase-1 P09874 CHEMBL3105 T06273 Enzyme NPT2563 TNKS2 Tankyrase-2 Q9H2K2 CHEMBL6154 Enzyme NPT2571 MAP3K8 Mitogen-activated protein kinase kinase kinase 8 P41279 CHEMBL4899 T46700 Enzyme Kinase Protein Kinase NPT2572 EPHB4 Ephrin type-B receptor 4 P54760 CHEMBL5147 T49507 Enzyme Kinase Protein Kinase NPT2573 FLT4 Vascular endothelial growth factor receptor 3 P35916 CHEMBL1955 T07303 Enzyme Kinase Protein Kinase NPT2574 INSR Insulin receptor P06213 CHEMBL1981 T85435 Enzyme Kinase Protein Kinase NPT2575 PDGFRB Platelet-derived growth factor receptor beta P09619 CHEMBL1913 T59102 Enzyme Kinase Protein Kinase NPT2576 TEK Tyrosine-protein kinase TIE-2 Q02763 CHEMBL4128 T92144 Enzyme Kinase Protein Kinase NPT259 MC4R Melanocortin receptor 4 P32245 CHEMBL259 T72458 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT2599 CYP2A13 Cytochrome P450 2A13 Q16696 CHEMBL3542436 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT2603 ADK Adenosine kinase P55263 CHEMBL3589 T91661 Enzyme NPT261 MAOA Monoamine oxidase A P21397 CHEMBL1951 T83875 Enzyme Oxidoreductase NPT262 CHRM1 Muscarinic acetylcholine receptor M1 P11229 CHEMBL216 T28893 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2626 MYLK Myosin light chain kinase, smooth muscle Q15746 CHEMBL2428 T97141 Enzyme Kinase Protein Kinase NPT2629 GFER FAD-linked sulfhydryl oxidase ALR P55789 CHEMBL1741189 Enzyme NPT263 CHRM2 Muscarinic acetylcholine receptor M2 P08172 CHEMBL211 T46185 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT264 CHRM3 Muscarinic acetylcholine receptor M3 P20309 CHEMBL245 T67684 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT265 CHRM4 Muscarinic acetylcholine receptor M4 P08173 CHEMBL1821 T50918 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2652 SAE1 SUMO-activating enzyme subunit 1 Q9UBE0 CHEMBL1615388 NPT266 CHRM5 Muscarinic acetylcholine receptor M5 P08912 CHEMBL2035 T79961 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2674 P2RX1 P2X purinoceptor 1 P51575 CHEMBL2094 T69091 Ion channel Ligand-gated ion channel P2X receptor NPT2680 ODC1 Ornithine decarboxylase P11926 CHEMBL1869 T60366 Enzyme Lyase NPT2691 CACNA1C Voltage-gated L-type calcium channel alpha-1C subunit Q13936 CHEMBL1940 T51115 Ion channel Voltage-gated ion channel Voltage-gated calcium channel NPT271 OPRD1 Delta opioid receptor P41143 CHEMBL236 T58992 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT2715 PTPRS Receptor-type tyrosine-protein phosphatase S Q13332 CHEMBL2396508 Enzyme Phosphatase Protein Phosphatase NPT272 OPRK1 Kappa opioid receptor P41145 CHEMBL237 T60693 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT2724 KDM2A Lysine-specific demethylase 2A Q9Y2K7 CHEMBL1938210 T71949 Epigenetic regulator Reader Plant homeodomain NPT2725 KDM4C Lysine-specific demethylase 4C Q9H3R0 CHEMBL6175 T73863 Epigenetic regulator Reader Methyl-lysine/arginine binding protein NPT2729 ABL1 Tyrosine-protein kinase ABL P00519 CHEMBL1862 T89747 Enzyme Kinase Protein Kinase NPT273 PDE5A Phosphodiesterase 5A O76074 CHEMBL1827 T07663 Enzyme Phosphodiesterase Phosphodiesterase 5 NPT2732 ALDH2 Aldehyde dehydrogenase P05091 CHEMBL1935 T44282 Enzyme Oxidoreductase NPT2736 ESRRA Estrogen-related receptor alpha P11474 CHEMBL3429 T72841 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group B NPT2737 ESRRB Estrogen-related receptor beta O95718 CHEMBL3751 T42025 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group B NPT274 PTAFR Platelet activating factor receptor P25105 CHEMBL250 T87023 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2742 AOX1 Aldehyde oxidase Q06278 CHEMBL3257 Enzyme NPT2752 DNMT1 DNA (cytosine-5)-methyltransferase 1 P26358 CHEMBL1993 T88304 Epigenetic regulator Writer DNA methyltransferase NPT277 CASP1 Caspase-1 P29466 CHEMBL4801 T98269 Enzyme Protease Cysteine protease NPT2776 HTR1E Serotonin 1e (5-HT1e) receptor P28566 CHEMBL2182 T84117 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT278 CTSG Cathepsin G P08311 CHEMBL4071 T86385 Enzyme Protease Serine protease NPT279 ELANE Leukocyte elastase P08246 CHEMBL248 T40332 Enzyme Protease Serine protease NPT2796 BCL2L1 Apoptosis regulator Bcl-X Q07817 CHEMBL4625 T56510 Ion channel Other ion channel Miscellaneous ion channel NPT280 MMP9 Matrix metalloproteinase 9 P14780 CHEMBL321 T93690 Enzyme Protease Metallo protease NPT2801 UBE2N Ubiquitin-conjugating enzyme E2 N P61088 CHEMBL6089 Enzyme NPT281 MAPK3 MAP kinase ERK1 P27361 CHEMBL3385 T23276 Enzyme Kinase Protein Kinase NPT2816 BRD4 Bromodomain-containing protein 4 O60885 CHEMBL1163125 T40556 Epigenetic regulator Reader Bromodomain NPT2818 DHFR Dihydrofolate reductase P00374 CHEMBL202 T17345 Enzyme Oxidoreductase NPT282 MAPK1 MAP kinase ERK2 P28482 CHEMBL4040 T58970 Enzyme Kinase Protein Kinase NPT283 MAPK14 MAP kinase p38 alpha Q16539 CHEMBL260 T65864 Enzyme Kinase Protein Kinase NPT285 EGFR Epidermal growth factor receptor erbB1 P00533 CHEMBL203 T59328 Enzyme Kinase Protein Kinase NPT2852 PRNP Prion protein P04156 CHEMBL4869 T08722 NPT2854 KCNA3 Voltage-gated potassium channel subunit Kv1.3 P22001 CHEMBL4633 T76914 Ion channel Voltage-gated ion channel Potassium channels NPT2856 SCN5A Sodium channel protein type V alpha subunit Q14524 CHEMBL1980 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT286 ERBB2 Receptor protein-tyrosine kinase erbB-2 P04626 CHEMBL1824 T96788 Enzyme Kinase Protein Kinase NPT2871 CDA Cytidine deaminase P32320 CHEMBL4502 T79027 Enzyme NPT2875 SLC28A3 Solute carrier family 28 member 3 Q9HAS3 CHEMBL5707 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT2876 SLC28A2 Sodium/nucleoside cotransporter 2 O43868 CHEMBL5780 T94627 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT2877 SLC28A1 Sodium/nucleoside cotransporter 1 O00337 CHEMBL5551 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT2886 KDM7A Lysine-specific demethylase 7 Q6ZMT4 CHEMBL2163177 T18784 Epigenetic regulator Reader Plant homeodomain NPT2887 PHF8 Histone lysine demethylase PHF8 Q9UPP1 CHEMBL1938212 T00933 Epigenetic regulator Reader Plant homeodomain NPT2892 XBP1 X-box-binding protein 1 P17861 CHEMBL1741176 NPT290 HTR2A Serotonin 2a (5-HT2a) receptor P28223 CHEMBL224 T32060 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT291 HTR2B Serotonin 2b (5-HT2b) receptor P41595 CHEMBL1833 T31204 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT292 HTR2C Serotonin 2c (5-HT2c) receptor P28335 CHEMBL225 T83813 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT2930 HBB Hemoglobin beta chain P68871 CHEMBL4331 T31825 NPT294 HTR6 Serotonin 6 (5-HT6) receptor P50406 CHEMBL3371 T16691 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT295 SLC6A4 Serotonin transporter P31645 CHEMBL228 T27812 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT296 SIGMAR1 Sigma opioid receptor Q99720 CHEMBL287 NPT298 TACR2 Neurokinin 2 receptor P21452 CHEMBL2327 T52790 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT30 PTGS1 Cyclooxygenase-1 P23219 CHEMBL221 T60529 Enzyme Oxidoreductase NPT300 TBXAS1 Thromboxane-A synthase P24557 CHEMBL1835 T78356 Enzyme Cytochrome P450 Cytochrome P450 family 5 NPT3000 MGLL Monoglyceride lipase Q99685 CHEMBL4191 T18664 Enzyme NPT301 FLT1 Vascular endothelial growth factor receptor 1 P17948 CHEMBL1868 T80782 Enzyme Kinase Protein Kinase NPT3020 PDGFRA Platelet-derived growth factor receptor alpha P16234 CHEMBL2007 T53524 Enzyme Kinase Protein Kinase NPT303 AVPR1A Vasopressin V1a receptor P37288 CHEMBL1889 T79232 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT3037 GPER1 G-protein coupled estrogen receptor 1 Q99527 CHEMBL5872 T65236 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT3068 LTB4R Leukotriene B4 receptor 1 Q15722 CHEMBL3911 T59626 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT31 PTGS2 Cyclooxygenase-2 P35354 CHEMBL230 T78464 Enzyme Oxidoreductase NPT3101 CA13 Carbonic anhydrase XIII Q8N1Q1 CHEMBL3912 Enzyme Lyase NPT3107 ROCK2 Rho-associated protein kinase 2 O75116 CHEMBL2973 T06093 Enzyme Kinase Protein Kinase NPT3109 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 Q9Y4K4 CHEMBL4852 Enzyme Kinase Protein Kinase NPT3111 LYN Tyrosine-protein kinase Lyn P07948 CHEMBL3905 T68163 Enzyme Kinase Protein Kinase NPT3114 DYRK1A Dual-specificity tyrosine-phosphorylation regulated kinase 1A Q13627 CHEMBL2292 T92803 Enzyme Kinase Protein Kinase NPT3116 CFTR Cystic fibrosis transmembrane conductance regulator P13569 CHEMBL4051 T55654 Ion channel Other ion channel Chloride channel NPT3124 PRKCH Protein kinase C eta P24723 CHEMBL3616 T40149 Enzyme Kinase Protein Kinase NPT3167 MPEG1 Macrophage-expressed gene 1 protein Q2M385 CHEMBL3414409 NPT3168 CSNK1A1 Casein kinase I alpha P48729 CHEMBL2793 T13075 Enzyme Kinase Protein Kinase NPT3172 PLA2G2A Phospholipase A2 group IIA P14555 CHEMBL3474 T19160 Enzyme NPT3193 SPHK1 Sphingosine kinase 1 Q9NYA1 CHEMBL4394 T86014 Enzyme NPT3194 SPHK2 Sphingosine kinase 2 Q9NRA0 CHEMBL3023 T31989 Enzyme NPT3201 RARA Retinoic acid receptor alpha P10276 CHEMBL2055 T94085 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group B NPT3204 FRK Tyrosine-protein kinase FRK P42685 CHEMBL4223 Enzyme Kinase Protein Kinase NPT3205 HCK Tyrosine-protein kinase HCK P08631 CHEMBL3234 T31406 Enzyme Kinase Protein Kinase NPT3207 MAPK10 c-Jun N-terminal kinase 3 P53779 CHEMBL2637 T00663 Enzyme Kinase Protein Kinase NPT3213 MKNK2 MAP kinase signal-integrating kinase 2 Q9HBH9 CHEMBL4204 Enzyme Kinase Protein Kinase NPT3223 PHKG2 Phosphorylase kinase gamma subunit 2 P15735 CHEMBL2349 T69208 Enzyme Kinase Protein Kinase NPT3227 FGFR3 Fibroblast growth factor receptor 3 P22607 CHEMBL2742 T91331 Enzyme Kinase Protein Kinase NPT3231 CLK4 Dual specificity protein kinase CLK4 Q9HAZ1 CHEMBL4203 T98225 Enzyme Kinase Protein Kinase NPT3238 TTK Dual specificity protein kinase TTK P33981 CHEMBL3983 T74977 Enzyme Kinase Protein Kinase NPT3239 NTRK1 Nerve growth factor receptor Trk-A P04629 CHEMBL2815 T07173 Enzyme Kinase Protein Kinase NPT3240 CDK5 Cyclin-dependent kinase 5 Q00535 CHEMBL4036 T20973 Enzyme Kinase Protein Kinase NPT3242 LIMK1 LIM domain kinase 1 P53667 CHEMBL3836 T70840 Enzyme Kinase Protein Kinase NPT3244 FER Tyrosine-protein kinase FER P16591 CHEMBL3982 T16993 Enzyme Kinase Protein Kinase NPT3245 TNK2 Tyrosine kinase non-receptor protein 2 Q07912 CHEMBL4599 T63220 Enzyme Kinase Protein Kinase NPT3246 JAK2 Tyrosine-protein kinase JAK2 O60674 CHEMBL2971 T08391 Enzyme Kinase Protein Kinase NPT3258 MAP3K20 Mixed lineage kinase 7 Q9NYL2 CHEMBL3886 T97821 Enzyme Kinase Protein Kinase NPT3262 PRKX Serine/threonine-protein kinase PRKX P51817 CHEMBL5818 Enzyme Kinase Protein Kinase NPT3263 PTK2B Protein tyrosine kinase 2 beta Q14289 CHEMBL5469 T07087 Enzyme Kinase Protein Kinase NPT3266 CSNK1D Casein kinase I delta P48730 CHEMBL2828 T87109 Enzyme Kinase Protein Kinase NPT3267 CSF1R Macrophage colony stimulating factor receptor P07333 CHEMBL1844 T55414 Enzyme Kinase Protein Kinase NPT3270 NTRK2 Neurotrophic tyrosine kinase receptor type 2 Q16620 CHEMBL4898 T84703 Enzyme Kinase Protein Kinase NPT3271 NTRK3 NT-3 growth factor receptor Q16288 CHEMBL5608 T51076 Enzyme Kinase Protein Kinase NPT3274 DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B Q9Y463 CHEMBL5543 T82720 Enzyme Kinase Protein Kinase NPT3275 IKBKE Inhibitor of nuclear factor kappa B kinase epsilon subunit Q14164 CHEMBL3529 T32335 Enzyme Kinase Protein Kinase NPT3276 TYK2 Tyrosine-protein kinase TYK2 P29597 CHEMBL3553 T78932 Enzyme Kinase Protein Kinase NPT3277 TYRO3 Tyrosine-protein kinase receptor TYRO3 Q06418 CHEMBL5314 T94880 Enzyme Kinase Protein Kinase NPT3280 MARK3 Serine/threonine-protein kinase c-TAK1 P27448 CHEMBL5600 T90553 Enzyme Kinase Protein Kinase NPT3282 MELK Maternal embryonic leucine zipper kinase Q14680 CHEMBL4578 T61518 Enzyme Kinase Protein Kinase NPT3287 ACVR1 Activin receptor type-1 Q04771 CHEMBL5903 T12091 Enzyme Kinase Protein Kinase NPT3290 SIK2 Serine/threonine-protein kinase SIK2 Q9H0K1 CHEMBL5699 T30495 Enzyme Kinase Protein Kinase NPT3309 LTK Leukocyte tyrosine kinase receptor P29376 CHEMBL5627 T47657 Enzyme Kinase Protein Kinase NPT3312 BLK Tyrosine-protein kinase BLK P51451 CHEMBL2250 T74307 Enzyme Kinase Protein Kinase NPT3315 BRSK1 BR serine/threonine-protein kinase 1 Q8TDC3 CHEMBL5650 T20053 Enzyme Kinase Protein Kinase NPT3316 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 O95819 CHEMBL6166 T71367 Enzyme Kinase Protein Kinase NPT3318 MARK4 MAP/microtubule affinity-regulating kinase 4 Q96L34 CHEMBL5754 Enzyme Kinase Protein Kinase NPT3320 MERTK Proto-oncogene tyrosine-protein kinase MER Q12866 CHEMBL5331 T55781 Enzyme Kinase Protein Kinase NPT3324 CDK8 Cell division protein kinase 8 P49336 CHEMBL5719 T10822 Enzyme Kinase Protein Kinase NPT3327 MAP3K10 Mitogen-activated protein kinase kinase kinase 10 Q02779 CHEMBL2873 T89323 Enzyme Kinase Protein Kinase NPT3331 STK3 Serine/threonine-protein kinase MST2 Q13188 CHEMBL4708 Enzyme Kinase Protein Kinase NPT3347 CDK9 Cyclin-dependent kinase 9 P50750 CHEMBL3116 T44458 Enzyme Kinase Protein Kinase NPT3365 PRKD2 Serine/threonine-protein kinase D2 Q9BZL6 CHEMBL4900 Enzyme Kinase Protein Kinase NPT3366 PRKD3 Protein kinase C nu O94806 CHEMBL2595 Enzyme Kinase Protein Kinase NPT3369 EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase P19525 CHEMBL5785 T04831 Enzyme Kinase Protein Kinase NPT3370 RET Tyrosine-protein kinase receptor RET P07949 CHEMBL2041 T60631 Enzyme Kinase Protein Kinase NPT3373 ROS1 Proto-oncogene tyrosine-protein kinase ROS P08922 CHEMBL5568 T69128 Enzyme Kinase Protein Kinase NPT3376 PIK3CB PI3-kinase p110-beta subunit P42338 CHEMBL3145 T95594 Enzyme NPT3381 MINK1 Misshapen-like kinase 1 Q8N4C8 CHEMBL5518 Enzyme Kinase Protein Kinase NPT3386 IRAK1 Interleukin-1 receptor-associated kinase 1 P51617 CHEMBL3357 T63846 Enzyme Kinase Protein Kinase NPT3388 MATK Tyrosine-protein kinase CTK P42679 CHEMBL4175 Enzyme Kinase Protein Kinase NPT3396 NEK4 Serine/threonine-protein kinase Nek4 P51957 CHEMBL5819 Enzyme Kinase Protein Kinase NPT3399 DYRK2 Dual-specificity tyrosine-phosphorylation regulated kinase 2 Q92630 CHEMBL4376 T39486 Enzyme Kinase Protein Kinase NPT3406 MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 Q12851 CHEMBL5330 T07191 Enzyme Kinase Protein Kinase NPT3417 TBK1 Serine/threonine-protein kinase TBK1 Q9UHD2 CHEMBL5408 T63024 Enzyme Kinase Protein Kinase NPT3425 IRAK4 Interleukin-1 receptor-associated kinase 4 Q9NWZ3 CHEMBL3778 T55398 Enzyme Kinase Protein Kinase NPT3431 TAOK1 Serine/threonine-protein kinase TAO1 Q7L7X3 CHEMBL5261 T97016 Enzyme Kinase Protein Kinase NPT3432 HIPK2 Homeodomain-interacting protein kinase 2 Q9H2X6 CHEMBL4576 T53952 Enzyme Kinase Protein Kinase NPT3439 HIPK4 Homeodomain-interacting protein kinase 4 Q8NE63 CHEMBL1075167 Enzyme Kinase Protein Kinase NPT3441 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 O14733 CHEMBL3530 T53159 Enzyme Kinase Protein Kinase NPT3442 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 O43318 CHEMBL5776 T04361 Enzyme Kinase Protein Kinase NPT3448 LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 Q5S007 CHEMBL1075104 T08123 Enzyme Kinase Protein Kinase NPT3456 SGK2 Serine/threonine-protein kinase Sgk2 Q9HBY8 CHEMBL5794 Enzyme Kinase Protein Kinase NPT3457 GRK5 G protein-coupled receptor kinase 5 P34947 CHEMBL5678 T69612 Enzyme Kinase Protein Kinase NPT3458 CDC7 Cell division cycle 7-related protein kinase O00311 CHEMBL5443 T81358 Enzyme Kinase Protein Kinase NPT346 TRPA1 Transient receptor potential cation channel subfamily A member 1 O75762 CHEMBL6007 T84040 Ion channel Voltage-gated ion channel Transient receptor potential channel NPT3460 DYRK3 Dual-specificity tyrosine-phosphorylation regulated kinase 3 O43781 CHEMBL4575 T97149 Enzyme Kinase Protein Kinase NPT3504 AKR1C3 Aldo-keto-reductase family 1 member C3 P42330 CHEMBL4681 T60857 Enzyme NPT3506 AKR1C4 Aldo-keto reductase family 1 member C4 P17516 CHEMBL4999 Enzyme NPT3507 AKR1C2 Aldo-keto reductase family 1 member C2 P52895 CHEMBL5847 Enzyme NPT3517 NOS2 Nitric oxide synthase, inducible P35228 CHEMBL4481 T02703 Enzyme NPT3549 GRM5 Metabotropic glutamate receptor 5 P41594 CHEMBL3227 T99347 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT3569 NOS1 Nitric-oxide synthase, brain P29475 CHEMBL3568 T16117 Enzyme NPT3579 CAPN1 Calpain 1 P07384 CHEMBL3891 Enzyme Protease Cysteine protease NPT3595 CTSK Cathepsin K P43235 CHEMBL268 T11388 Enzyme Protease Cysteine protease NPT36 SRC Tyrosine-protein kinase SRC P12931 CHEMBL267 T85943 Enzyme Kinase Protein Kinase NPT366 NQO2 Quinone reductase 2 P16083 CHEMBL3959 T75498 Enzyme NPT37 STAT1 Signal transducer and activator of transcription 1-alpha/beta P42224 CHEMBL6101 T64205 NPT3708 SCN9A Sodium channel protein type IX alpha subunit Q15858 CHEMBL4296 T12119 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3711 SCN11A Sodium channel protein type XI alpha subunit Q9UI33 CHEMBL5167 T34123 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3712 SCN8A Sodium channel protein type VIII alpha subunit Q9UQD0 CHEMBL5202 T58741 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3713 SCN4A Sodium channel protein type IV alpha subunit P35499 CHEMBL2072 T02546 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3714 SCN3A Sodium channel protein type III alpha subunit Q9NY46 CHEMBL5163 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3715 SCN2A Sodium channel protein type II alpha subunit Q99250 CHEMBL4187 T29678 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3716 SCN1A Sodium channel protein type I alpha subunit P35498 CHEMBL1845 T58440 Ion channel Voltage-gated ion channel Voltage-gated sodium channel NPT3727 LDHB L-lactate dehydrogenase B chain P07195 CHEMBL4940 Enzyme NPT3728 MDM2 p53-binding protein Mdm-2 Q00987 CHEMBL5023 T10937 NPT3735 NTSR1 Neurotensin receptor 1 P30989 CHEMBL4123 T02728 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT3737 GRIK2 Glutamate receptor ionotropic kainate 2 Q13002 CHEMBL3683 T58178 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3741 GRIA1 Glutamate receptor ionotropic, AMPA 1 P42261 CHEMBL2009 T33584 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3742 GRIA2 Glutamate receptor ionotropic, AMPA 2 P42262 CHEMBL4016 T42392 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3743 GRIA4 Glutamate receptor ionotropic, AMPA 4 P48058 CHEMBL3190 T96235 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3744 GRIK1 Glutamate receptor ionotropic kainate 1 P39086 CHEMBL1918 T73495 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3745 GRIK5 Glutamate receptor ionotropic kainate 5 Q16478 CHEMBL2675 T87930 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT3746 GRIK3 Glutamate receptor ionotropic kainate 3 Q13003 CHEMBL3684 T68876 Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NPT38 STAT3 Signal transducer and activator of transcription 3 P40763 CHEMBL4026 T86803 NPT3812 SLCO4C1 Solute carrier organic anion transporter family member 4C1 Q6ZQN7 CHEMBL2073690 T36053 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT3820 EIF4A1 Eukaryotic initiation factor 4A-I P60842 CHEMBL2052028 Enzyme NPT3825 P2RY1 Purinergic receptor P2Y1 P47900 CHEMBL4315 T67818 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT3826 P2RY2 Purinergic receptor P2Y2 P41231 CHEMBL4398 T93515 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT3838 ADA Adenosine deaminase P00813 CHEMBL1910 T03661 Enzyme Hydrolase NPT3839 KCNA5 Voltage-gated potassium channel subunit Kv1.5 P22460 CHEMBL4306 T17569 Ion channel Voltage-gated ion channel Potassium channels NPT3938 CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Q9GZU7 CHEMBL1795098 Enzyme NPT3953 SERPINE1 Plasminogen activator inhibitor-1 P05121 CHEMBL3475 T15556 NPT3960 BCR Bcr/Abl fusion protein P11274 CHEMBL2096618 Enzyme Kinase Protein Kinase NPT3969 ATP12A Potassium-transporting ATPase alpha chain 2 P54707 CHEMBL2933 Enzyme Hydrolase NPT3970 KLF5 Kruppel-like factor 5 Q13887 CHEMBL1293249 NPT3971 TAS2R31 Taste receptor type 2 member 31 P59538 CHEMBL2034804 Membrane receptor Taste family G protein-coupled receptor Taste receptor (taste family GPCR) NPT3997 PTPN22 Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Q9Y2R2 CHEMBL2889 Enzyme Phosphatase Protein Phosphatase NPT4001 FABP3 Fatty acid binding protein muscle P05413 CHEMBL3344 NPT4003 FFAR4 G-protein coupled receptor 120 Q5NUL3 CHEMBL5339 T51385 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4011 HTR4 Serotonin 4 (5-HT4) receptor Q13639 CHEMBL1875 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4015 MMP14 Matrix metalloproteinase 14 P50281 CHEMBL3869 T65019 Enzyme Protease Metallo protease NPT4018 SCD Acyl-CoA desaturase O00767 CHEMBL5555 T10897 Enzyme NPT4030 OXER1 Oxoeicosanoid receptor 1 Q8TDS5 CHEMBL1628461 T68834 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4034 HKDC1 Putative hexokinase HKDC1 Q2TB90 CHEMBL1741200 Enzyme NPT4036 SLC47A2 Multidrug and toxin extrusion protein 2 Q86VL8 CHEMBL1743127 T78127 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT4037 SLC47A1 Multidrug and toxin extrusion protein 1 Q96FL8 CHEMBL1743126 T39676 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT4046 MTNR1A Melatonin receptor 1A P48039 CHEMBL1945 T97613 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4047 MTNR1B Melatonin receptor 1B P49286 CHEMBL1946 T48268 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4054 HRAS Transforming protein p21/H-Ras-1 P01112 CHEMBL2167 T71081 NPT4059 ADORA2B Adenosine A2b receptor P29275 CHEMBL255 T86679 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4088 GRK6 G protein-coupled receptor kinase 6 P43250 CHEMBL6144 Enzyme Kinase Protein Kinase NPT4093 HASPIN Serine/threonine-protein kinase haspin Q8TF76 CHEMBL1075163 Enzyme Kinase Protein Kinase NPT41 AKR1B1 Aldose reductase P15121 CHEMBL1900 T26623 Enzyme NPT410 CHRNA7 Neuronal acetylcholine receptor protein alpha-7 subunit P36544 CHEMBL2492 T34429 Ion channel Ligand-gated ion channel Nicotinic acetylcholine receptor NPT4104 CASP2 Caspase-2 P42575 CHEMBL4884 T81103 Enzyme Protease Cysteine protease NPT4106 AOC3 Amine oxidase, copper containing Q16853 CHEMBL3437 Enzyme NPT4110 EBP 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Q15125 CHEMBL4931 T25317 Enzyme NPT4115 XPO1 Exportin-1 O14980 CHEMBL5661 T51407 NPT4119 GPR18 N-arachidonyl glycine receptor Q14330 CHEMBL2384898 T72267 Membrane receptor Family A G protein-coupled receptor NPT4120 GPR55 G-protein coupled receptor 55 Q9Y2T6 CHEMBL1075322 T87670 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT4163 PTPRCAP Protein tyrosine phosphatase receptor type C-associated protein Q14761 CHEMBL4806 Enzyme NPT4166 FKBP1A FK506-binding protein 1A P62942 CHEMBL1902 Enzyme Isomerase NPT4181 PEPD Xaa-Pro dipeptidase P12955 CHEMBL4185 T94823 Enzyme Protease Metallo protease NPT4218 NT5E 5'-nucleotidase P21589 CHEMBL5957 T65116 Enzyme NPT4219 CHAT Choline acetylase P28329 CHEMBL4039 Enzyme NPT424 CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 P32297 CHEMBL3068 T74166 Ion channel Ligand-gated ion channel Nicotinic acetylcholine receptor NPT425 HTR3A Serotonin 3a (5-HT3a) receptor P46098 CHEMBL1899 T64591 Ion channel Ligand-gated ion channel 5HT3 receptor NPT4252 TLR9 Toll-like receptor 9 Q9NR96 CHEMBL5804 T11451 Membrane receptor Toll-like and Il-1 receptors NPT426 GLRA1 Glycine receptor subunit alpha-1 P23415 CHEMBL5845 T50269 Ion channel Ligand-gated ion channel Glycine receptor NPT4266 MT-ND4 NADH-ubiquinone oxidoreductase chain 4 P03905 CHEMBL4499 Enzyme Oxidoreductase NPT4274 EPHX1 Epoxide hydrolase 1 P07099 CHEMBL1968 Enzyme Protease Serine protease NPT429 CHRNA4 Neuronal acetylcholine receptor protein alpha-4 subunit P43681 CHEMBL1882 T70967 Ion channel Ligand-gated ion channel Nicotinic acetylcholine receptor NPT4309 XIAP Inhibitor of apoptosis protein 3 P98170 CHEMBL4198 T81892 NPT4324 GLRA2 Glycine receptor subunit alpha-2 P23416 CHEMBL5871 Ion channel Ligand-gated ion channel Glycine receptor NPT4342 SLC6A15 Sodium-dependent neutral amino acid transporter B(0)AT2 Q9H2J7 CHEMBL3351189 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT439 BCHE Butyrylcholinesterase P06276 CHEMBL1914 Enzyme Hydrolase NPT4407 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Q16875 CHEMBL2331053 T23787 NPT441 CYP19A1 Cytochrome P450 19A1 P11511 CHEMBL1978 T13260 Enzyme Cytochrome P450 Cytochrome P450 family 19 NPT4418 ENPP2 Autotaxin Q13822 CHEMBL3691 Enzyme NPT45 USP2 Ubiquitin carboxyl-terminal hydrolase 2 O75604 CHEMBL1293227 T95183 Enzyme NPT4559 F2RL1 Proteinase-activated receptor 2 P55085 CHEMBL5963 T62841 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT4562 GRM3 Metabotropic glutamate receptor 3 Q14832 CHEMBL2888 T02719 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT4563 GRM2 Metabotropic glutamate receptor 2 Q14416 CHEMBL5137 T62820 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT4565 GRM4 Metabotropic glutamate receptor 4 Q14833 CHEMBL2736 T99402 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT4567 GRM8 Metabotropic glutamate receptor 8 O00222 CHEMBL3228 T77548 Membrane receptor Family C G protein-coupled receptor Small molecule receptor (family C GPCR) NPT4576 FOLH1 Glutamate carboxypeptidase II Q04609 CHEMBL1892 Enzyme Protease Metallo protease NPT4581 PLCG1 Phospholipase C-gamma-1 P19174 CHEMBL3964 Enzyme NPT4582 VCP Transitional endoplasmic reticulum ATPase P55072 CHEMBL1075145 T12646 Transporter Primary active transporter Endoplasmic reticular retrotranslocon family NPT46 THRB Thyroid hormone receptor beta-1 P10828 CHEMBL1947 T98933 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group A NPT4674 APAF1 Apoptotic protease-activating factor 1 O14727 CHEMBL1795093 NPT4684 TGM2 Protein-glutamine gamma-glutamyltransferase P21980 CHEMBL2730 T05387 Enzyme NPT469 CTSL Cathepsin L P07711 CHEMBL3837 T41141 Enzyme Protease Cysteine protease NPT4698 PLD1 Phospholipase D1 Q13393 CHEMBL2536 T38996 Enzyme NPT4699 PLD2 Phospholipase D2 O14939 CHEMBL2734 T10383 Enzyme NPT47 RECQL ATP-dependent DNA helicase Q1 P46063 CHEMBL1293236 Enzyme NPT4712 P2RY14 Purinergic receptor P2Y14 Q15391 CHEMBL4518 T16555 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT472 TRPV1 Vanilloid receptor Q8NER1 CHEMBL4794 T83193 Ion channel Voltage-gated ion channel Transient receptor potential channel NPT4735 PDE4B Phosphodiesterase 4B Q07343 CHEMBL275 T47941 Enzyme Phosphodiesterase Phosphodiesterase 4 NPT477 APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G Q9HC16 CHEMBL1741217 Enzyme NPT4786 TXN2 Thioredoxin, mitochondrial Q99757 CHEMBL2189153 NPT4787 TXN Thioredoxin P10599 CHEMBL2010624 T85616 NPT48 KDM4E Lysine-specific demethylase 4D-like B2RXH2 CHEMBL1293226 Epigenetic regulator Eraser Lysine demethylase NPT483 LMNA Prelamin-A/C P02545 CHEMBL1293235 NPT4848 HSPA1A Heat shock 70 kDa protein 1 P0DMV8 CHEMBL5460 NPT4884 ATR Serine-protein kinase ATR Q13535 CHEMBL5024 T97155 Enzyme Kinase Protein Kinase NPT4897 IDE Insulin-degrading enzyme P14735 CHEMBL1293287 T81900 Enzyme NPT49 APEX1 DNA-(apurinic or apyrimidinic site) lyase P27695 CHEMBL5619 T13348 Enzyme NPT4907 TDP2 Tyrosyl-DNA phosphodiesterase 2 O95551 CHEMBL2169736 T04696 Enzyme NPT491 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Q02750 CHEMBL3587 T35940 Enzyme Kinase Protein Kinase NPT4947 ATP1A1 Sodium/potassium-transporting ATPase alpha-1 chain P05023 CHEMBL1807 T40800 Enzyme Hydrolase NPT4948 GSTK1 Glutathione S-transferase kappa 1 Q9Y2Q3 CHEMBL4491 Enzyme NPT497 MGAM Maltase-glucoamylase O43451 CHEMBL2074 T92777 Enzyme Hydrolase NPT50 TDP1 Tyrosyl-DNA phosphodiesterase 1 Q9NUW8 CHEMBL1075138 T33492 Enzyme NPT5009 GSTP1 Glutathione S-transferase Pi P09211 CHEMBL3902 T21669 Enzyme NPT501 GLA Alpha-galactosidase A P06280 CHEMBL2524 T21678 Enzyme NPT5013 CMA1 Chymase P23946 CHEMBL4068 T05114 Enzyme Protease Serine protease NPT5015 OXTR Oxytocin receptor P30559 CHEMBL2049 T84486 Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) NPT503 FUCA1 Alpha-L-fucosidase I P04066 CHEMBL4176 Enzyme NPT5051 RBBP9 Putative hydrolase RBBP9 O75884 CHEMBL1075121 T12084 Enzyme NPT5071 CACNA1D Voltage-gated L-type calcium channel alpha-1D subunit Q01668 CHEMBL4138 T24793 Ion channel Voltage-gated ion channel Voltage-gated calcium channel NPT51 MAPT Microtubule-associated protein tau P10636 CHEMBL1293224 T45593 NPT510 UGCG Ceramide glucosyltransferase Q16739 CHEMBL2063 Enzyme Transferase NPT5100 PDE2A Phosphodiesterase 2A O00408 CHEMBL2652 T77400 Enzyme Phosphodiesterase Phosphodiesterase 2 NPT5104 PDE3A Phosphodiesterase 3A Q14432 CHEMBL241 Enzyme Phosphodiesterase Phosphodiesterase 3 NPT5105 PDE3B Phosphodiesterase 3B Q13370 CHEMBL290 T21357 Enzyme Phosphodiesterase Phosphodiesterase 3 NPT5106 PDE10A Phosphodiesterase 10A Q9Y233 CHEMBL4409 T84133 Enzyme Phosphodiesterase Phosphodiesterase 10 NPT5108 GLI2 Zinc finger protein GLI2 P10070 CHEMBL5119 T29672 NPT511 SI Sucrase-isomaltase P14410 CHEMBL2748 Enzyme NPT5136 TUBB1 Tubulin beta-1 chain Q9H4B7 CHEMBL1915 T84397 NPT514 AGL Glycogen debranching enzyme P35573 CHEMBL5272 Enzyme NPT5152 FUCA2 Alpha-L-fucosidase 2 Q9BTY2 CHEMBL2271 Enzyme NPT5155 FABP2 Fatty acid binding protein intestinal P12104 CHEMBL4879 NPT5199 TUBB3 Tubulin beta-3 chain Q13509 CHEMBL2597 NPT52 PKM Pyruvate kinase isozymes M1/M2 P14618 CHEMBL1075189 T65889 Enzyme NPT5220 MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Q9UDY8 CHEMBL3632452 Enzyme Hydrolase NPT5234 SLC22A12 Solute carrier family 22 member 12 Q96S37 CHEMBL6120 T86057 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT5235 FABP5 Fatty acid binding protein epidermal Q01469 CHEMBL3674 T21507 NPT5236 TLR2 Toll-like receptor 2 O60603 CHEMBL4163 T82078 Membrane receptor Toll-like and Il-1 receptors NPT524 ATM Serine-protein kinase ATM Q13315 CHEMBL3797 T97196 Enzyme Kinase Protein Kinase NPT525 HCAR2 Hydroxycarboxylic acid receptor 2 Q8TDS4 CHEMBL3785 T00864 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT5256 HTR1F Serotonin 1f (5-HT1f) receptor P30939 CHEMBL1805 T78656 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT5270 IL1B Interleukin-1 beta P01584 CHEMBL1909490 T42000 NPT5283 FUT7 Alpha-(1,3)-fucosyltransferase 7 Q11130 CHEMBL3596077 Enzyme Transferase NPT5318 CRHR1 Corticotropin releasing factor receptor 1 P34998 CHEMBL1800 T45262 Membrane receptor Family B G protein-coupled receptor Peptide receptor (family B GPCR) NPT532 KDM4A Lysine-specific demethylase 4A O75164 CHEMBL5896 Epigenetic regulator Reader Methyl-lysine/arginine binding protein NPT537 RAB9A Ras-related protein Rab-9A P51151 CHEMBL1293294 T66350 NPT5373 METAP2 Methionine aminopeptidase 2 P50579 CHEMBL3922 T75596 Enzyme Protease Metallo protease NPT538 NPC1 Niemann-Pick C1 protein O15118 CHEMBL1293277 NPT5386 CREB1 Cyclic AMP-responsive element-binding protein 1 P16220 CHEMBL5587 T47496 NPT539 TP53 Cellular tumor antigen p53 P04637 CHEMBL4096 T82051 NPT540 NR1H4 Bile acid receptor FXR Q96RI1 CHEMBL2047 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group H NPT5406 NOD2 Nucleotide-binding oligomerization domain-containing protein 2 Q9HC29 CHEMBL1293266 T75643 NPT541 NR3C2 Mineralocorticoid receptor P08235 CHEMBL1994 T72168 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C NPT542 PGR Progesterone receptor P06401 CHEMBL208 T22939 Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C NPT543 NR1I2 Pregnane X receptor O75469 CHEMBL3401 T82702 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group I NPT545 PLA2G1B Phospholipase A2 group 1B P04054 CHEMBL4426 T31479 Enzyme NPT546 RXRA Retinoid X receptor alpha P19793 CHEMBL2061 T13726 Nuclear receptor Nuclear hormone receptor subfamily 2 Nuclear hormone receptor subfamily 2 group B NPT5463 SLC7A11 Cystine/glutamate transporter Q9UPY5 CHEMBL1075149 T11615 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT5493 SLC5A4 Low affinity sodium-glucose cotransporter Q9NY91 CHEMBL1770047 T22583 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT5626 MCOLN3 MCOLN3 protein Q8TDD5 CHEMBL1293243 T14241 Ion channel Voltage-gated ion channel Transient receptor potential channel NPT5649 HDAC10 Histone deacetylase 10 Q969S8 CHEMBL5103 T94324 Epigenetic regulator Eraser Histone deacetylase NPT567 MMP3 Matrix metalloproteinase 3 P08254 CHEMBL283 T86702 Enzyme Protease Metallo protease NPT568 MMP2 Matrix metalloproteinase-2 P08253 CHEMBL333 T68251 Enzyme Protease Metallo protease NPT5689 GSTA1 Glutathione S-transferase A1 P08263 CHEMBL3409 Enzyme NPT57 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 Q07820 CHEMBL4361 T14912 NPT570 ALOX5 Arachidonate 5-lipoxygenase P09917 CHEMBL215 T93566 Enzyme Oxidoreductase NPT58 BLM Bloom syndrome protein P54132 CHEMBL1293237 Enzyme NPT582 MAOB Monoamine oxidase B P27338 CHEMBL2039 T83011 Enzyme Oxidoreductase NPT585 NR0B1 Nuclear receptor subfamily 0 group B member 1 P51843 CHEMBL1795094 T23191 Nuclear receptor Nuclear hormone receptor subfamily 0 Nuclear hormone receptor subfamily 0 group B NPT588 TNKS Tankyrase-1 O95271 CHEMBL6164 Enzyme NPT59 POLB DNA polymerase beta P06746 CHEMBL2392 Enzyme NPT591 GSK3B Glycogen synthase kinase-3 beta P49841 CHEMBL262 T70977 Enzyme Kinase Protein Kinase NPT592 ROCK1 Rho-associated protein kinase 1 Q13464 CHEMBL3231 T07102 Enzyme Kinase Protein Kinase NPT60 GAA Lysosomal alpha-glucosidase P10253 CHEMBL2608 T31514 Enzyme Hydrolase NPT601 CTSV Cathepsin L2 O60911 CHEMBL3272 T93653 Enzyme Protease Cysteine protease NPT606 PRSS1 Trypsin I P07477 CHEMBL209 T27602 Enzyme Protease Serine protease NPT6080 LSS Lanosterol synthase P48449 CHEMBL3593 T56175 Enzyme NPT61 GBA Beta-glucocerebrosidase P04062 CHEMBL2179 T84173 Enzyme NPT613 SLC22A1 Solute carrier family 22 member 1 O15245 CHEMBL5685 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT6188 NOX1 NADPH oxidase 1 Q9Y5S8 CHEMBL1287628 T32137 Transporter Transmembrane 1-electron transfer carriers NPT620 PCSK7 Subtilisin/kexin type 7 Q16549 CHEMBL2232 T33211 Enzyme Protease Serine protease NPT622 SLCO2B1 Solute carrier organic anion transporter family member 2B1 O94956 CHEMBL1743124 T34064 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT627 CYP2B6 Cytochrome P450 2B6 P20813 CHEMBL4729 T11793 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT628 CYP2C8 Cytochrome P450 2C8 P10632 CHEMBL3721 Enzyme Cytochrome P450 Cytochrome P450 family 2 NPT6327 NCOA3 Nuclear receptor coactivator 3 Q9Y6Q9 CHEMBL1615382 T26774 Epigenetic regulator Writer Histone acetyltransferase NPT640 SLC5A1 Sodium/glucose cotransporter 1 P13866 CHEMBL4979 T54771 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT641 SLC5A2 Sodium/glucose cotransporter 2 P31639 CHEMBL3884 T81100 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT644 LDHA L-lactate dehydrogenase A chain P00338 CHEMBL4835 T15053 Enzyme NPT645 DAO D-amino-acid oxidase P14920 CHEMBL5485 T33124 Enzyme NPT6507 CPB1 Carboxypeptidase B P15086 CHEMBL2552 T36725 Enzyme Protease Metallo protease NPT6513 EBPL Emopamil-binding protein-like Q9BY08 CHEMBL2311238 NPT6574 NCOA1 Nuclear receptor coactivator 1 Q15788 CHEMBL1615387 Epigenetic regulator Writer Histone acetyltransferase NPT6631 GANC Neutral alpha-glucosidase C Q8TET4 CHEMBL2520 Enzyme NPT665 SLC22A6 Solute carrier family 22 member 6 Q4U2R8 CHEMBL1641347 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT668 ABCB1 P-glycoprotein 1 P08183 CHEMBL4302 T25258 Transporter Primary active transporter ATP-binding cassette NPT669 SLC22A8 Solute carrier family 22 member 8 Q8TCC7 CHEMBL1641348 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT670 F2 Thrombin P00734 CHEMBL204 T94033 Enzyme Protease Serine protease NPT676 GSK3A Glycogen synthase kinase-3 alpha P49840 CHEMBL2850 T85250 Enzyme Kinase Protein Kinase NPT677 F3 Coagulation factor III P13726 CHEMBL4081 T72702 NPT684 HDAC1 Histone deacetylase 1 Q13547 CHEMBL325 Epigenetic regulator Eraser Histone deacetylase NPT685 HDAC2 Histone deacetylase 2 Q92769 CHEMBL1937 T51191 Epigenetic regulator Eraser Histone deacetylase NPT686 HDAC3 Histone deacetylase 3 O15379 CHEMBL1829 T05090 Epigenetic regulator Eraser Histone deacetylase NPT687 HDAC8 Histone deacetylase 8 Q9BY41 CHEMBL3192 T28887 Epigenetic regulator Eraser Histone deacetylase NPT69 MMP1 Matrix metalloproteinase-1 P03956 CHEMBL332 T52450 Enzyme Protease Metallo protease NPT692 HDAC6 Histone deacetylase 6 Q9UBN7 CHEMBL1865 T22274 Epigenetic regulator Eraser Histone deacetylase NPT72 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Q9NPD5 CHEMBL1743121 T02565 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT721 RELA Nuclear factor NF-kappa-B p65 subunit Q04206 CHEMBL5533 NPT728 AKT1 Serine/threonine-protein kinase AKT P31749 CHEMBL4282 T67619 Enzyme Kinase Protein Kinase NPT73 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Q9Y6L6 CHEMBL1697668 T46814 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT74 JUN Proto-oncogene c-JUN P05412 CHEMBL4977 T69085 NPT740 BACE1 Beta-secretase 1 P56817 CHEMBL4822 Enzyme Protease Aspartic protease NPT741 TYR Tyrosinase P14679 CHEMBL1973 T97035 Enzyme Oxidoreductase NPT745 GPBAR1 G-protein coupled bile acid receptor 1 Q8TDU6 CHEMBL5409 T86273 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT748 SLC10A1 Bile acid transporter Q14973 CHEMBL5287 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT760 PRKCB Protein kinase C beta P05771 CHEMBL3045 T40276 Enzyme Kinase Protein Kinase NPT761 PRKCE Protein kinase C epsilon Q02156 CHEMBL3582 T93262 Enzyme Kinase Protein Kinase NPT77 TTR Transthyretin P02766 CHEMBL3194 T86462 NPT78 APP Beta amyloid A4 protein P05067 CHEMBL2487 T87024 NPT792 ALOX15 Arachidonate 15-lipoxygenase P16050 CHEMBL2903 T16042 Enzyme NPT796 PMP22 Peripheral myelin protein 22 Q01453 CHEMBL1293298 NPT801 ALPI Intestinal alkaline phosphatase P09923 CHEMBL5573 Enzyme NPT802 ALPL Alkaline phosphatase, tissue-nonspecific isozyme P05186 CHEMBL5979 T09538 Enzyme NPT808 SLC6A1 GABA transporter 1 P30531 CHEMBL1903 T62184 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT810 SLC6A11 GABA transporter 3 P48066 CHEMBL5208 T38200 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT831 PLK1 Serine/threonine-protein kinase PLK1 P53350 CHEMBL3024 T59273 Enzyme Kinase Protein Kinase NPT833 BTK Tyrosine-protein kinase BTK Q06187 CHEMBL5251 Enzyme Kinase Protein Kinase NPT861 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic O75874 CHEMBL2007625 T69563 Enzyme NPT862 EPHX2 Epoxide hydratase P34913 CHEMBL2409 T35734 Enzyme Protease Serine protease NPT864 L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 Q9Y468 CHEMBL1287622 Epigenetic regulator Reader Methyl-lysine/arginine binding protein NPT865 FASN Fatty acid synthase P49327 CHEMBL4158 T16514 Enzyme Transferase NPT866 PPARA Peroxisome proliferator-activated receptor alpha Q07869 CHEMBL239 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group C NPT869 FFAR1 Free fatty acid receptor 1 O14842 CHEMBL4422 T25608 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT870 CD38 Lymphocyte differentiation antigen CD38 P28907 CHEMBL4660 T10877 Enzyme NPT876 GDA Guanine deaminase Q9Y2T3 CHEMBL3129 Enzyme NPT880 PRKCG Protein kinase C gamma P05129 CHEMBL2938 T47107 Enzyme Kinase Protein Kinase NPT881 PRKCD Protein kinase C delta Q05655 CHEMBL2996 T49368 Enzyme Kinase Protein Kinase NPT887 PRKCQ Protein kinase C theta Q04759 CHEMBL3920 T72295 Enzyme Kinase Protein Kinase NPT894 SERPINA6 Corticosteroid binding globulin P08185 CHEMBL2421 T88452 NPT895 SHBG Testis-specific androgen-binding protein P04278 CHEMBL3305 NPT901 UGT1A1 UDP-glucuronosyltransferase 1-1 P22309 CHEMBL1287617 Enzyme NPT911 CDC25B Dual specificity phosphatase Cdc25B P30305 CHEMBL4804 T46365 Enzyme Phosphatase Protein Phosphatase NPT912 AHCY Adenosylhomocysteinase P23526 CHEMBL2664 T68698 Enzyme NPT918 HSP90AA1 Heat shock protein HSP 90-alpha P07900 CHEMBL3880 T18477 NPT92 HTR1A Serotonin 1a (5-HT1a) receptor P08908 CHEMBL214 T78709 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT93 SMN1;SMN2 Survival motor neuron protein Q16637 CHEMBL1293232 T95695 Epigenetic regulator Reader Methyl-lysine/arginine binding protein NPT935 NQO1 Quinone reductase 1) P15559 CHEMBL3623 T52389 Enzyme NPT94 ALDH1A1 Aldehyde dehydrogenase 1A1 P00352 CHEMBL3577 Enzyme NPT940 MTOR Serine/threonine-protein kinase mTOR P42345 CHEMBL2842 T75243 Enzyme NPT942 SLC2A1 Glucose transporter P11166 CHEMBL2535 T89458 Transporter Electrochemical transporter SLC superfamily of solute carriers NPT946 ACLY ATP-citrate synthase P53396 CHEMBL3720 T52189 Enzyme NPT947 CA1 Carbonic anhydrase I P00915 CHEMBL261 T13201 Enzyme Lyase NPT948 CA9 Carbonic anhydrase IX Q16790 CHEMBL3594 T64567 Enzyme Lyase NPT949 CA12 Carbonic anhydrase XII O43570 CHEMBL3242 T16987 Enzyme Lyase NPT954 CA14 Carbonic anhydrase XIV Q9ULX7 CHEMBL3510 Enzyme Lyase NPT955 CA7 Carbonic anhydrase VII P43166 CHEMBL2326 Enzyme Lyase NPT956 PTGES Prostaglandin E synthase O14684 CHEMBL5658 T02562 Enzyme NPT958 HSD17B3 Estradiol 17-beta-dehydrogenase 3 P37058 CHEMBL4234 Enzyme NPT96 THPO Thrombopoietin P40225 CHEMBL1293256 NPT967 XDH Xanthine dehydrogenase P47989 CHEMBL1929 T40954 Enzyme Oxidoreductase NPT973 HTR1B Serotonin 1b (5-HT1b) receptor P28222 CHEMBL1898 T07806 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT974 HTR1D Serotonin 1d (5-HT1d) receptor P28221 CHEMBL1983 T11072 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT976 TAAR1 Trace amine-associated receptor 1 Q96RJ0 CHEMBL5857 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT979 CASP3 Caspase-3 P42574 CHEMBL2334 T57943 Enzyme Protease Cysteine protease NPT98 KCNH2 HERG Q12809 CHEMBL240 Ion channel Voltage-gated ion channel Potassium channels NPT980 BCL2 Apoptosis regulator Bcl-2 P10415 CHEMBL4860 T47387 Ion channel Other ion channel Miscellaneous ion channel NPT981 IKBKB Inhibitor of nuclear factor kappa B kinase beta subunit O14920 CHEMBL1991 T78429 Enzyme Kinase Protein Kinase NPT987 HRH3 Histamine H3 receptor Q9Y5N1 CHEMBL264 T64765 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT988 HRH4 Histamine H4 receptor Q9H3N8 CHEMBL3759 T26500 Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) NPT99 PPARG Peroxisome proliferator-activated receptor gamma P37231 CHEMBL235 T58921 Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group C