List of protein families with GO categories currently covered by SVMProt

List of protein families with GO categories currently covered by SVMProt.

Predictive performance on these SVM, PNN, KNN are given in Sensitivity TP/(TP+FN), Specificity or Recall TN/(TN+FP), Precision TP/(TP + FP), Accuracy (TP+TN)/(TP+FN+TN+FP),
and MCC ().

Protein family

GO Category

SVM PNN KNN

Sensitivity (%) Specificity (%) Precision (%) Accuracy (%) MCC Sensitivity (%) Specificity (%) Precision (%) Accuracy (%) MCC Sensitivity (%) Specificity (%) Precision (%) Accuracy (%) MCC

EC1.1 Oxidoreductases acting on the CH-OH group of donors
GO:0016614 82.47 96.12 72.01 94.65 0.74 - - - - - - - - - -

EC1.2 Oxidoreductases acting on the aldehyde or oxo group of donors
GO:0016903 78.96 98.46 77.08 97.25 0.77 - - - - - - - - - -

EC1.3 Oxidoreductases acting on the CH-CH group of donors
GO:0016627 66.36 98.86 56.15 98.16 0.60 74.92 99.08 96.38 93.12 0.81 86.82 91.09 75.49 90.07 0.74

EC1.4 Oxidoreductases acting on the CH-NH2 group of donors
GO:0016638 65.79 99.48 65.79 98.98 0.66 77.28 99.21 94.15 96.11 0.83 92.46 93.79 70.24 93.61 0.77

EC1.5 Oxidoreductases acting on the CH-NH group of donors
GO:0016645 58.57 99.58 66.13 99.01 0.62 64.18 99.17 92.55 94.32 0.74 84.45 95.84 75.95 94.31 0.77

EC1.6 Oxidoreductases acting on NADH or NADPH
GO:0016651 94.51 98.24 92.7 97.52 0.92 - - - - - - - - - -

EC1.7 Oxidoreductases acting on other nitrogenous compounds as donors
GO:0016661 65.91 99.74 69.05 99.45 0.67 - - - - - - - - - -

EC1.8 Oxidoreductases acting on a sulfur group of donors
GO:0016667 58.82 99.6 66.67 99.05 0.62 - - - - - 90.35 95.14 82.03 94.2 0.82

EC1.9 Oxidoreductases acting on a heme group of donors
GO:0016675 99.26 99.04 99.01 99.15 0.98 - - - - - - - - - -

EC1.10 Oxidoreductases acting on diphenols and related substances as donors
GO:0016679 76.47 99.4 68.42 99.02 0.72 84.99 99.48 90.51 98.68 0.87 88.45 99.5 90.93 98.91 0.89

EC1.11 Oxidoreductases acting on a peroxide as acceptor
GO:0016684 86.9 99.56 86.9 99.15 0.87 82.29 98.81 88.87 97.09 0.84 82.08 97.74 80.35 96.16 0.79

EC1.13 Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases)
GO:0016701 55.77 99.74 69.05 99.29 0.62 - - - - - 79.44 99.04 82.8 97.96 0.80

EC1.14 Oxidoreductases acting on paired donors with incorporation reduction of molecular oxygen
GO:0016705 70.99 98.86 62 98.15 0.66 73.51 99.24 92.54 96.32 0.81 76.74 95.45 69.16 93.26 0.69

EC1.15 Oxidoreductases acting on superoxide as acceptor
GO:0016721 92.5 99.6 91.74 99.28 0.92 94.03 99.76 97.05 99.31 0.95 92.63 99.57 94.49 99.06 0.93

EC1.17 Oxidoreductases acting on CH2 groups
GO:0016725 78.18 99.82 82.69 99.59 0.80 82.3 99.16 95.32 96.26 0.87 - - - - -

EC1.18 Oxidoreductases acting on iron-sulfur proteins as donors
GO:0016730 91.76 99.56 78 99.43 0.84 87.74 99.62 92.35 99.02 0.89 83.69 99.15 83.52 98.39 0.82

EC2.1 Transferases transferring one-carbon groups
GO:0016741 68.1 85 20.43 84.1 0.32 - - - - - - - - - -

EC2.2 Transferases transferring aldehyde or ketone residues
GO:0016744 83.87 99.7 89.66 99.23 0.87 - - - - - - - - - -

EC2.3 Acyltransferases
GO:0016764 81.67 97.28 87.89 94.24 0.81 - - - - - - - - - -

EC2.4 Glycosyltransferases
GO:0042123 70.49 94.19 41.51 92.88 0.51 - - - - - - - - - -

EC2.5 Transferases transferring alkyl or aryl groups, other than methyl groups
GO:0016765 70.26 98.14 59.57 97.1 0.63 - - - - - - - - - -

EC2.6 Transferases transferring nitrogenous groups
GO:0016769 70.09 99.03 60.48 98.42 0.64 - - - - - - - - - -

EC2.7 Transferases transferring phosphorus-containing groups
GO:0016772 81.66 89.05 79.76 86.5 0.70 - - - - - - - - - -

EC2.8 Transferases transferring sulfur-containing groups
GO:0016782 66.67 99.78 64.52 99.59 0.66 89.29 98.79 94.85 96.89 0.90 92.51 94.34 79.54 93.99 0.82

EC2.9 Transferring selenium-containing groups
GO:0016785 95.95 99.99 99.33 99.92 0.97 92.38 99.88 92.53 99.75 0.92 83.72 99.69 81.43 99.44 0.82

EC3.1 Hydrolases acting on ester bonds
GO:0016788 71.11 90.6 45.61 88.65 0.51 - - - - - - - - - -

EC3.2 Glycosylases
GO:0016798 84.54 94.85 84.01 92.35 0.79 - - - - - - - - - -

EC3.3 Hydrolases acting on ether bonds
GO:0016801 59.26 99.36 50 98.94 0.54 85.23 99.9 97.18 99.32 0.91 83.98 99.39 84.26 98.81 0.84

EC3.4 Hydrolases acting on peptide bonds (Peptidases)
GO:0008233 74.58 94.2 48.62 92.85 0.57 - - - - - - - - - -

EC3.5 Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds
GO:0016810 60.47 97.78 54.17 96.23 0.56 - - - - - - - - - -

EC3.6 Hydrolases acting on acid anhydrides
GO:0016817 91.6 95.57 75.74 95.05 0.81 - - - - - - - - - -

EC3.7 Acting on carbon-carbon bonds
GO:0016822 96.48 99.89 94.56 99.82 0.95 91.19 99.91 95.19 99.74 0.93 84.4 99.43 78.03 99.07 0.81

EC3.8 Acting on halide bonds
GO:0016824 89.45 99.9 82.79 99.84 0.86 74.37 99.94 87.57 99.81 0.81 51.06 99.84 77.5 99.32 0.62

EC4.1 Carbon-carbon lyases
GO:0016830 89.82 89.35 83.9 89.53 0.78 - - - - - - - - - -

EC4.2 Carbon-oxygen lyases
GO:0016835 80.4 92.24 80.8 88.82 0.73 - - - - - - - - - -

EC4.3 Carbon-nitrogen lyases
GO:0016840 74.36 99.26 43.94 99.07 0.57 85.13 98.84 82.59 98 0.83 83.04 98.19 74.05 97.31 0.77

EC4.4 Carbon-sulfur lyases
GO:0016846 60.34 99.86 83.33 99.41 0.71 83.78 99.18 86.84 98.25 0.84 76.99 98.99 82.65 97.69 0.79

EC4.6 Phosphorus-oxygen lyases
GO:0016849 67.07 82.06 5.77 81.82 0.17 60.49 98.8 73.85 96.77 0.65 72.73 98.04 66.78 96.74 0.68

EC5.1 Racemases and Epimerases
GO:0016854 53.03 99.4 53.85 98.8 0.53 69.26 98.7 94.49 91.54 0.76 80.66 93.81 79.95 90.73 0.74

EC5.2 Cis-trans-Isomerases
GO:0016859 66.67 99.52 75 98.83 0.70 88.36 98.66 93.51 96.82 0.89 89.89 97.23 86.98 95.98 0.86

EC5.3 Intramolecular oxidoreductases
GO:0016860 75.84 98.02 57.69 97.26 0.65 - - - - - - - - - -

EC5.4 Intramolecular transferases
GO:0016866 54.55 99.38 57.53 98.71 0.56 - - - - - - - - - -

EC5.5 Intramolecular lyases
GO:0016872 70.09 99.03 60.48 98.42 0.64 75.39 99.86 82.59 99.65 0.79 62.36 99.83 76.69 99.48 0.69

EC5.99 Other Isomerases
GO:0016853 92.17 99.56 87.43 99.33 0.89 94.49 99.62 98.34 98.63 0.95 96.64 94.76 80.52 95.1 0.85

EC6.1 Ligases forming carbon-oxygen bonds
GO:0016875 90.79 97.32 91.37 95.76 0.88 - - - - - - - - - -

EC6.2 Ligases forming carbon-sulfur bonds
GO:0016877 79.69 99.75 79.69 99.51 0.79 89.5 98.88 92.33 97.66 0.89 91.99 95.67 75.63 95.21 0.81

EC6.3 Ligases forming carbon-nitrogen bonds
GO:0016879 83.76 95.46 86.73 92.4 0.80 - - - - - - - - - -

EC6.4 Ligases forming carbon-carbon bonds
GO:0016885 63.64 99.92 87.5 99.61 0.74 86.73 98.94 89.43 97.79 0.87 94.83 96.44 72.6 96.29 0.81

EC6.5 Ligases forming phosphoric ester bonds
GO:0016886 70.97 99.88 78.57 99.7 0.75 88.46 99.77 96.94 98.9 0.92 91.96 96.31 66.27 95.99 0.76

EC6.6 Forming nitrogen�metal bonds
GO:0051002 89.29 99.93 91.74 99.83 0.91 79.46 99.95 94.01 99.77 0.87 88.43 98.71 55.73 98.53 0.69

TC1.A alpha-type channels
GO:0005216 86.77 99.28 78.85 98.9 0.82 - - - - - - - - - -

TC1.B beta-barrel porins
GO:0015288 70.65 99.6 69.15 99.23 0.69 - - - - - - - - - -

TC1.C Pore-forming toxins (proteins and peptides)
GO:0005216 78.74 99.77 86.96 99.36 0.82 - - - - - - - - - -

TC1.E Holins
GO:0034290 78.57 99.94 93.22 99.69 0.85 - - - - - - - - - -

TC2.A porters (symporters, uniporters, antiporters)
GO:0015291 87.26 98.51 80.43 97.77 0.82 - - - - - - - - - -

TC2.A.1 Major facilitator family (MFS)
GO:0005215 76.54 97.86 28.7 97.62 0.46 - - - - - - - - - -

TC2.A.3 Amino acid-polyamine-organocation (APC) family
GO:0005215 93.94 99.36 40.26 99.34 0.62 - - - - - - - - - -

TC2.A.6 Resistance-nodulation-cell division (RND) family
GO:0005215 71.88 99.41 34.85 99.28 0.50 - - - - - - - - - -

TC2.C Ion-gradient-driven energizers
GO:0015291 76.47 99.79 87.5 99.35 0.81 - - - - - - - - - -

TC3.A P-P-bond-hydrolysis-driven transporters
GO:0015405 78.68 97.63 86.25 94.62 0.79 - - - - - - - - - -

TC3.A.1 ATP-binding cassette (ABC) family
GO:0043190 94.1 91.55 36.41 91.68 0.56 - - - - - - - - - -

TC3.A.3 P-type ATPase (P-ATPase) family
GO:0015662 97.06 95.68 17.37 95.69 0.40 - - - - - - - - - -

TC3.A.5 Type II (general) secretory pathway (IISP) family
GO:0015405 85.94 91.54 15.17 91.44 0.35 - - - - - - - - - -

TC3.A.15 The Outer Membrane Protein Secreting Main Terminal Branch (MTB) family
GO:0015405 60.61 98.05 12.35 97.88 0.26 - - - - - - - - - -

TC3.D Oxidoreduction-driven transporters
GO:0015453 91.14 99.5 94.49 98.79 0.92 - - - - - - - - - -

TC3.E Light absorption-driven transporters
GO:0015454 96.11 99.85 97.29 99.65 0.96 - - - - - - - - - -

TC4.A Phosphotransfer-driven group translocators
GO:0008982 82.7 99.66 87.93 99.16 0.85 - - - - - - - - - -

TC9.A Recognized transporters of unknown biochemical mechanism
GO:0005215 78.79 99.3 75.14 98.76 0.76 - - - - - - - - - -

TC9.B Putative uncharacterized transport proteins
GO:0005215 80.17 98.39 82.72 96.8 0.79 - - - - - - - - - -

7 transmembrane receptor (rhodopsin family and chemoreceptor)
GO:0004930 96.9 99.16 97.33 98.62 0.96 - - - - - - - - - -

7 transmembrane receptor (secretin family)
GO:0004930 90.7 94.91 24.02 94.84 0.45 - - - - - - - - - -

7 transmembrane receptor (metabotropic glutamate family)
GO:0004930 89.86 95.77 16.76 95.72 0.37 - - - - - - - - - -

7 transmembrane receptor (odorant receptor)
GO:0004930 97.44 97.56 17.59 97.56 0.41 - - - - - - - - - -

G protein coupled receptors
GO:0004930 95.62 98.07 94.53 97.43 0.93 94.05 99.9 93.38 99.81 0.94 96.63 98.94 64.11 98.9 0.78

Nuclear receptors
GO:0003700 89.47 97.57 90.2 95.94 0.87 - - - - - - - - - -

DNA-binding proteins
GO:0003677 90.4 85.56 77.77 87.29 0.74 68.97 98.06 85.19 94 0.73 81.86 90.19 61.38 88.85 0.65

RNA-binding proteins
GO:0003723 97.76 95.98 69.04 96.13 0.81 - - - - - - - - - -

mRNA-binding proteins
GO:0003729 79.27 96.48 37.9 96.02 0.53 - - - - - - - - - -

rRNA-binding proteins
GO:0019843 94.06 98.68 59.01 98.59 0.74 95.84 98.68 93.56 98.2 0.94 96.49 98.29 91.42 98.01 0.93

tRNA-binding proteins
GO:0000049 94.12 99.9 90.57 99.84 0.92 - - - - - - - - - -

Structural proteins (Matrix protein,Core protein,Viral occlusion body,Keratin)
GO:0005198 98.46 99.19 98.49 98.93 0.97 - - - - - - - - - -

Lectin
GO:0030246 81.63 85.7 5.31 85.66 0.17 - - - - - - - - - -

Chlorophyll
GO:0016168 97.35 99.84 97.91 99.67 0.97 - - - - - - - - - -

Photoreceptor
GO:0009881 92.88 99.62 95.47 99.09 0.94 80.77 99.98 91.3 99.94 0.86 61.17 99.78 41.72 99.68 0.50

DNA-directed DNA polymerase
GO:0003887 81.93 98.65 88.45 96.78 0.83 80.2 99.67 66.39 99.51 0.73 51.06 99.39 41.18 98.99 0.46

DNA-directed RNA polymerase
GO:0003899 88.95 97.95 93.48 95.72 0.88 - - - - - - - - - -

Lipid-binding
GO:0008289 84.43 99.87 93.38 99.54 0.88 66.92 99.72 72.1 99.37 0.69 72.82 99.63 71.23 99.3 0.71

All lipid-binding proteins
GO:0008289 89.88 96.95 95.25 94.09 0.88 - - - - - - - - - -

Calcium-binding
GO:0005509 86.26 88.22 57.04 87.92 0.63 - - - - - - - - - -

Cobalt-binding
GO:0050897 81.63 99.91 98.09 98.93 0.89 - - - - - - - - - -

Copper-binding
GO:0005507 83.51 98.11 72.76 97.28 0.77 - - - - - - - - - -

Iron-binding
GO:0005506 93.96 91.37 64.86 91.74 0.73 - - - - - - - - - -

Magnesium-binding
GO:0000287 81.16 87.9 80.91 85.29 0.69 - - - - - - - - - -

Manganese-binding
GO:0030145 85.36 94.51 71.88 93.22 0.74 - - - - - - - - - -

Nickel-binding
GO:0016151 77.61 99.18 70.59 98.64 0.73 - - - - - - - - - -

Potassium-binding
GO:0030955 90.39 99.95 98.69 99.56 0.94 - - - - - - - - - -

Sodium-binding
GO:0031402 90.91 99.86 97.39 99.37 0.94 - - - - - - - - - -

Zinc-binding
GO:0008270 74.91 98.02 97.32 86.7 0.75 - - - - - - - - - -

Metal-binding
GO:0046872 78.07 88.01 95.14 80.55 0.59 - - - - - - - - - -

Actin binding
GO:0003779 94.94 99.45 83.25 99.33 0.88 - - - - - - - - - -

Chitin-binding
GO:0008061 92.42 99.9 84.78 99.86 0.88 75.36 99.91 82.81 99.77 0.79 93.63 98.6 29.86 98.57 0.53

Folate-binding
GO:0005542 96.97 100 98.97 99.99 0.98 94.95 100 98.95 99.98 0.97 94.12 99.86 62.75 99.84 0.77

Antioxidant
GO:0016209 89 99.97 89.9 99.94 0.89 86 99.94 78.9 99.9 0.82 69.05 99.92 73.73 99.82 0.71

Calmodulin-binding
GO:0005516 87.2 99.96 90.51 99.9 0.89 82.93 99.93 83.95 99.85 0.83 69.96 99.44 41.6 99.27 0.54

Cyclin
GO:0061575 97.96 99.98 88.89 99.98 0.93 89.8 99.94 66.67 99.93 0.77 74.74 99.84 52.21 99.78 0.62

Cyclosporin
GO:0042277 87.5 100 100 99.99 0.93 75 99.99 80 99.98 0.77 84.21 99.93 35.56 99.92 0.55

Cytokine
GO:0005125 91.29 99.93 89.8 99.88 0.91 - - - - - 70.66 99.85 80 99.61 0.75

Elongation factor
GO:0003746 97.48 99.97 98.78 99.91 0.98 84.14 99.87 94.01 99.49 0.89 95.84 99.56 83.71 99.47 0.89

Excision nuclease
GO:0004518 97.39 99.99 99 99.97 0.98 93.46 99.93 91.37 99.87 0.92 95.75 99.48 58.84 99.45 0.75

Eye lens protein
GO:0005212 98 100 98 99.99 0.98 100 99.95 71.43 99.95 0.84 96.77 99.97 82.19 99.96 0.89

Growth factor
GO:0008083 88.89 99.92 88.52 99.85 0.89 86.01 99.91 86.72 99.82 0.86 76.74 99.87 81.91 99.7 0.79

GTPase activation
GO:0005096 92.92 99.94 83.33 99.92 0.88 86.73 99.93 78.4 99.89 0.82 61.84 99.56 42.24 99.36 0.51

Guanine-nucleotide releasing factor
GO:0005085 83.33 99.95 77.38 99.91 0.80 89.74 99.85 55.56 99.83 0.71 93.79 99.18 31.72 99.15 0.54

Heparin-binding
GO:0008201 89.13 99.92 73.87 99.89 0.81 90.22 99.86 61.03 99.83 0.74 70.73 99.93 75 99.84 0.73

Hormone
GO:0005179 87.69 99.92 90.68 99.81 0.89 76.88 99.9 87.97 99.7 0.82 69.78 99.83 80.45 99.52 0.75

Initiation factor
GO:0003743 91.36 99.86 93.02 99.7 0.92 74.21 99.93 95.41 99.43 0.84 77.63 99.65 81.18 99.22 0.79

Ion channel
GO:0005216 90.58 99.82 87.77 99.68 0.89 - - - - - 75.77 99.03 57.46 98.63 0.66

Metalloenzyme inhibitor
GO:0004857 83.33 99.99 93.75 99.98 0.88 88.89 99.98 80 99.97 0.84 70.73 99.96 63.04 99.93 0.67

Porin
GO:0015288 93.9 99.99 93.9 99.97 0.94 87.8 99.98 88.89 99.95 0.88 79.81 99.95 82.18 99.9 0.81

Protease inhibitor
GO:0030414 79.79 99.93 85.23 99.83 0.82 75.53 99.57 47.18 99.44 0.59 66.79 99.73 63.39 99.49 0.65

Protein phosphatase inhibitor
GO:0004864 96 99.99 88.89 99.99 0.92 - - - - - 64.86 99.99 88.89 99.96 0.76

SH3-binding
GO:0017124 94.12 99.99 95.52 99.98 0.95 - - - - - 58.16 99.92 65.52 99.82 0.62

Sigma factor
GO:0016987 87.04 99.98 85.45 99.96 0.86 83.33 99.97 81.82 99.95 0.82 68.33 99.9 50.62 99.85 0.59

Storage protein
GO:0045735 50 99.98 40 99.97 0.45 - - - - - 63.64 99.88 22.95 99.86 0.39

Vitamin C binding
GO:0031418 91.89 100 100 99.99 0.96 97.3 99.89 47.37 99.89 0.68 81.63 99.94 61.54 99.91 0.71

Zinc-finger
GO:0070742; GO:0071535 56.32 99.91 97.79 96.99 0.73 78.44 97.34 67.91 96.08 0.71 71.6 96.8 66.77 94.72 0.66

TC8.A Auxiliary transport proteins
GO:0006810 74.25 99.76 89.21 99.08 0.81 - - - - - - - - - -

Cell adhesion
GO:0007155 85.93 99.11 84.06 98.43 0.84 - - - - - - - - - -

Chlorophyll biosynthesis
GO:0015995 86.44 88.8 16.45 88.74 0.35 - - - - - - - - - -

Herbicide resistance
GO:0009635 95.22 99.86 95.22 99.72 0.95 96.72 99.98 89.39 99.98 0.93 95.16 99.97 85.51 99.97 0.90

Photorespiration
GO:0009853 99.7 99.66 99.44 99.67 0.99 95.15 99.96 92.45 99.93 0.94 96.35 99.92 86.83 99.9 0.92

Photosynthesis
GO:0015979 93.3 98.06 82.28 97.64 0.87 81.62 99.64 87.88 99.09 0.84 86.21 99.36 81.3 98.94 0.83

Plant defense
GO:0006952 88.65 99.13 82.81 98.66 0.85 - - - - - - - - - -

DNA condensation
GO:0030261 87.64 99.45 80.41 99.16 0.84 69.83 99.89 66.39 99.79 0.68 83.21 99.9 72.67 99.84 0.77

DNA integration
GO:0015074 86.63 98.07 87.05 96.58 0.85 72.79 99.96 87.61 99.86 0.80 68.92 99.85 63.75 99.74 0.66

DNA recombination
GO:0006310 85.74 97.38 92.05 94.34 0.85 77.59 98.92 76.95 97.96 0.76 67.46 99.25 80.3 97.87 0.73

DNA repair
GO:0006281 88.66 96.81 85.92 95.34 0.84 64.32 99.3 90.43 96.05 0.74 67.58 96.81 67.98 94.14 0.65

DNA replication
GO:0006260 85.6 96.64 76.77 95.37 0.79 76.78 98.9 77.64 97.85 0.76 59.69 98.5 66.57 96.65 0.62

Lipid degradation
GO:0016042 78.9 99.94 97.4 99.31 0.87 75.08 99.93 89.56 99.73 0.82 64.75 99.77 72.04 99.44 0.68

Lipid metabolism
GO:0006629 79.5 99.17 66.67 98.77 0.72 72.08 98.5 80.32 96.43 0.74 71.83 97.78 73.92 95.69 0.71

Lipid synthesis
GO:0008610 82.22 99.61 95.07 98.14 0.87 - - - - - - - - - -

Lipid transport
GO:0006869 79.49 99.81 80.52 99.6 0.80 71.51 99.93 82.55 99.8 0.77 59.43 99.79 60.87 99.58 0.60

Lipopolysaccharide biosynthesis
GO:0009103 76.64 99.83 88.98 99.43 0.82 - - - - - - - - - -

Lipoprotein
GO:0055097; GO:0055096 90.59 98.54 94.88 96.71 0.91 - - - - - - - - - -

Immune response
GO:0006955 86.84 99.95 97.06 99.7 0.92 - - - - - - - - - -

Inflammatory response
GO:0006954 87.5 99.75 73.68 99.65 0.80 75.37 99.69 46.98 99.6 0.59 55.21 99.81 59.22 99.6 0.57

Innate immunity
GO:0045087 89.66 99.9 86.67 99.82 0.88 65.52 99.93 85.88 99.71 0.75 84.64 99.24 49.74 99.12 0.65

Virulent protein
GO:0009405 95.38 99.92 96.49 99.82 0.96 70.3 99.92 87.65 99.66 0.78 63.98 99.14 49.15 98.69 0.56

mRNA capping
GO:0006370 80.77 99.85 79.25 99.72 0.80 82.19 99.97 91.6 99.9 0.87 61.54 99.72 46.83 99.57 0.54

mRNA slicing
- 77.27 99.3 77.27 98.65 0.77 - - - - - - - - - -

Actin capping
GO:0051693 95.1 99.98 93.27 99.97 0.94 91.18 99.9 70.99 99.87 0.81 73.33 99.93 55 99.9 0.63

DNA replication inhibitor
GO:0008156 97.93 99.99 97.93 99.97 0.98 97.11 99.94 91.09 99.92 0.94 93.93 99.89 83.75 99.85 0.89

Mitogen
GO:0051781 92.74 99.93 93.24 99.86 0.93 83.6 99.92 91.2 99.75 0.87 85.19 99.77 79.59 99.62 0.82

Pathogenesis-related protein
GO:0009607 96.33 99.98 98.01 99.94 0.97 94.87 99.93 94.17 99.88 0.94 91.26 99.91 91.67 99.81 0.91

Protein synthesis inhibitor
GO:0017148 86.06 99.97 92.81 99.91 0.89 81.82 99.93 84.91 99.85 0.83 79.43 99.8 63.18 99.71 0.71

Vasoactive
GO:0050880 94.96 99.99 97.41 99.98 0.96 93.28 99.95 86.05 99.93 0.89 86.23 99.96 88.15 99.91 0.87

Amphibian defense peptide
GO:0006952 100 100 75 100 0.87 66.67 99.98 25 99.98 0.41 100 99.98 66.67 99.98 0.82

Chromatin regulator
GO:0016568 76.43 99.5 62.86 99.24 0.69 68.24 99.65 68.41 99.3 0.68 59.9 98.99 47.73 98.4 0.53

Chromophore
GO:0018298 93.83 99.93 93.83 99.87 0.94 86.91 99.87 88.44 99.73 0.88 89.38 99.49 68.2 99.37 0.77

Covalent protein-RNA linkage
GO:0018144 96.3 99.96 80 99.96 0.88 90.74 99.99 92.45 99.98 0.92 74.55 99.79 32.54 99.75 0.49

Hypotensive agent
GO:0008217 66.67 100 100 100 0.82 66.67 99.99 33.33 99.99 0.47 87.5 99.99 58.33 99.98 0.71

Integrin
GO:0007229 90.91 100 95.24 99.99 0.93 86.36 99.93 41.3 99.92 0.60 90.32 99.92 47.46 99.91 0.66

Motor protein
GO:0098840 89.47 99.97 91.07 99.94 0.90 80.7 99.95 82.88 99.89 0.82 64.32 99.46 39.03 99.27 0.50

Neuropeptide
GO:0007218 86.21 99.93 66.67 99.91 0.75 79.31 99.96 76.67 99.93 0.78 79.75 99.89 60 99.85 0.69

Signal transduction inhibitor
GO:0009968 84.62 99.91 49.25 99.89 0.65 84.62 99.98 80.49 99.96 0.82 87.04 99.94 65.28 99.92 0.75

Transmembrane
GO:0016021 90.12 86.66 79.06 87.9 0.75 - - - - - - - - - -

Outer membrane
GO:0009279 92.71 86.42 32.12 86.83 0.50 - - - - - - - - - -

Coat proteins
GO:0030117 84.77 99.41 85.2 98.85 0.84 - - - - - - - - - -

Envelope proteins
GO:0019031 90 99.5 84.38 99.22 0.87 - - - - - - - - - -

Photosystem I
GO:0009522 97.6 84.76 23.5 85.35 0.44 88.37 99.94 87.36 99.89 0.88 86.8 99.9 81.82 99.84 0.84

Photosystem II
GO:0009523 97.47 99.48 97.07 99.18 0.97 - - - - - - - - - -

Collagen
GO:0005581 96.83 99.99 96.83 99.99 0.97 96.83 99.94 74.39 99.94 0.85 84.47 99.98 92.55 99.94 0.88

Flavoprotein
GO:0045251 87.93 99.36 88.02 98.78 0.87 73.73 99.54 89.55 98.24 0.81 71.3 97.81 64.25 96.43 0.66

Mutator protein
GO:1990633 83.82 100 98.28 99.97 0.91 77.94 99.91 62.35 99.87 0.70 70 99.95 73.13 99.9 0.71

Viral nucleoprotein
GO:0019013 89.91 99.95 91.93 99.89 0.91 87.72 99.98 96.15 99.9 0.92 79.06 99.87 77.73 99.74 0.78

cAMP binding
- 97.29 99.97 98.55 99.92 0.98 - - - - - 85.6 99.75 86.19 99.5 0.85

cGMP binding
- 98.46 100 98.46 99.99 0.98 - - - - - 82.19 99.79 41.96 99.76 0.58

Milk protein
- 92.16 100 97.92 99.99 0.95 - - - - - 74.07 99.98 86.96 99.95 0.80

Suppressor of RNA silencing
- 95.4 99.98 98.57 99.93 0.97 91.03 100 99.75 99.89 0.95 93.05 99.03 51.94 98.96 0.69

Allergen
- 85.19 99.88 60.53 99.84 0.71 86.42 99.92 69.31 99.89 0.77 74.11 99.95 79.81 99.87 0.77

Biotin binding
- 77.78 99.99 73.68 99.98 0.75 - - - - - 83.33 99.71 17.86 99.7 0.39

Cadmium binding
- 80 99.99 80 99.99 0.80 - - - - - 75 99.98 66.67 99.97 0.71

Chaperone
- 84.61 99.88 98.39 98.68 0.91 80.29 98.87 85.91 97.41 0.82 85.36 97.98 78.03 97 0.80

Chloride binding
- 92 99.98 92 99.96 0.92 - - - - - 71.64 99.85 62.34 99.76 0.66

Molybdenum binding
- 84.3 99.98 92.73 99.93 0.88 - - - - - 70.83 99.66 43.22 99.56 0.55

Muscle protein
- 95.38 99.96 90.51 99.95 0.93 89.23 99.91 77.33 99.87 0.83 79.77 99.89 76.67 99.81 0.78

Plastoquinone binding
- 96.7 99.98 98.65 99.94 0.97 - - - - - 93.46 99.76 82.03 99.69 0.87

Schiff base binding
- 93.2 99.86 93.56 99.73 0.93 - - - - - 73.3 99.7 83.4 99.17 0.77

Selenium binding
- 91.84 99.99 96.77 99.97 0.94 - - - - - 74 99.95 78.72 99.88 0.76

Sialic acid binding
- 76.19 100 94.12 99.98 0.85 90.48 99.9 35.19 99.9 0.57 81.82 99.96 64.29 99.95 0.73

Thiamine pyrophosphate binding
- 96.53 99.94 93.58 99.91 0.95 87.7 99.85 83.73 99.75 0.85 74.64 99.44 53.85 99.22 0.63

Ubiquinone binding
- 94.07 99.93 97.41 99.76 0.95 82.58 99.67 88.13 99.19 0.85 91.5 99.32 79.16 99.1 0.85

Last update: 29 Nov 2017

Protein family	GO Category	SVM					PNN					KNN
Protein family	GO Category	Sensitivity (%)	Specificity (%)	Precision (%)	Accuracy (%)	MCC	Sensitivity (%)	Specificity (%)	Precision (%)	Accuracy (%)	MCC	Sensitivity (%)	Specificity (%)	Precision (%)	Accuracy (%)	MCC
EC1.1 Oxidoreductases acting on the CH-OH group of donors	GO:0016614	82.47	96.12	72.01	94.65	0.74	-	-	-	-	-	-	-	-	-	-
EC1.2 Oxidoreductases acting on the aldehyde or oxo group of donors	GO:0016903	78.96	98.46	77.08	97.25	0.77	-	-	-	-	-	-	-	-	-	-
EC1.3 Oxidoreductases acting on the CH-CH group of donors	GO:0016627	66.36	98.86	56.15	98.16	0.60	74.92	99.08	96.38	93.12	0.81	86.82	91.09	75.49	90.07	0.74
EC1.4 Oxidoreductases acting on the CH-NH2 group of donors	GO:0016638	65.79	99.48	65.79	98.98	0.66	77.28	99.21	94.15	96.11	0.83	92.46	93.79	70.24	93.61	0.77
EC1.5 Oxidoreductases acting on the CH-NH group of donors	GO:0016645	58.57	99.58	66.13	99.01	0.62	64.18	99.17	92.55	94.32	0.74	84.45	95.84	75.95	94.31	0.77
EC1.6 Oxidoreductases acting on NADH or NADPH	GO:0016651	94.51	98.24	92.7	97.52	0.92	-	-	-	-	-	-	-	-	-	-
EC1.7 Oxidoreductases acting on other nitrogenous compounds as donors	GO:0016661	65.91	99.74	69.05	99.45	0.67	-	-	-	-	-	-	-	-	-	-
EC1.8 Oxidoreductases acting on a sulfur group of donors	GO:0016667	58.82	99.6	66.67	99.05	0.62	-	-	-	-	-	90.35	95.14	82.03	94.2	0.82
EC1.9 Oxidoreductases acting on a heme group of donors	GO:0016675	99.26	99.04	99.01	99.15	0.98	-	-	-	-	-	-	-	-	-	-
EC1.10 Oxidoreductases acting on diphenols and related substances as donors	GO:0016679	76.47	99.4	68.42	99.02	0.72	84.99	99.48	90.51	98.68	0.87	88.45	99.5	90.93	98.91	0.89
EC1.11 Oxidoreductases acting on a peroxide as acceptor	GO:0016684	86.9	99.56	86.9	99.15	0.87	82.29	98.81	88.87	97.09	0.84	82.08	97.74	80.35	96.16	0.79
EC1.13 Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases)	GO:0016701	55.77	99.74	69.05	99.29	0.62	-	-	-	-	-	79.44	99.04	82.8	97.96	0.80
EC1.14 Oxidoreductases acting on paired donors with incorporation reduction of molecular oxygen	GO:0016705	70.99	98.86	62	98.15	0.66	73.51	99.24	92.54	96.32	0.81	76.74	95.45	69.16	93.26	0.69
EC1.15 Oxidoreductases acting on superoxide as acceptor	GO:0016721	92.5	99.6	91.74	99.28	0.92	94.03	99.76	97.05	99.31	0.95	92.63	99.57	94.49	99.06	0.93
EC1.17 Oxidoreductases acting on CH2 groups	GO:0016725	78.18	99.82	82.69	99.59	0.80	82.3	99.16	95.32	96.26	0.87	-	-	-	-	-
EC1.18 Oxidoreductases acting on iron-sulfur proteins as donors	GO:0016730	91.76	99.56	78	99.43	0.84	87.74	99.62	92.35	99.02	0.89	83.69	99.15	83.52	98.39	0.82
EC2.1 Transferases transferring one-carbon groups	GO:0016741	68.1	85	20.43	84.1	0.32	-	-	-	-	-	-	-	-	-	-
EC2.2 Transferases transferring aldehyde or ketone residues	GO:0016744	83.87	99.7	89.66	99.23	0.87	-	-	-	-	-	-	-	-	-	-
EC2.3 Acyltransferases	GO:0016764	81.67	97.28	87.89	94.24	0.81	-	-	-	-	-	-	-	-	-	-
EC2.4 Glycosyltransferases	GO:0042123	70.49	94.19	41.51	92.88	0.51	-	-	-	-	-	-	-	-	-	-
EC2.5 Transferases transferring alkyl or aryl groups, other than methyl groups	GO:0016765	70.26	98.14	59.57	97.1	0.63	-	-	-	-	-	-	-	-	-	-
EC2.6 Transferases transferring nitrogenous groups	GO:0016769	70.09	99.03	60.48	98.42	0.64	-	-	-	-	-	-	-	-	-	-
EC2.7 Transferases transferring phosphorus-containing groups	GO:0016772	81.66	89.05	79.76	86.5	0.70	-	-	-	-	-	-	-	-	-	-
EC2.8 Transferases transferring sulfur-containing groups	GO:0016782	66.67	99.78	64.52	99.59	0.66	89.29	98.79	94.85	96.89	0.90	92.51	94.34	79.54	93.99	0.82
EC2.9 Transferring selenium-containing groups	GO:0016785	95.95	99.99	99.33	99.92	0.97	92.38	99.88	92.53	99.75	0.92	83.72	99.69	81.43	99.44	0.82
EC3.1 Hydrolases acting on ester bonds	GO:0016788	71.11	90.6	45.61	88.65	0.51	-	-	-	-	-	-	-	-	-	-
EC3.2 Glycosylases	GO:0016798	84.54	94.85	84.01	92.35	0.79	-	-	-	-	-	-	-	-	-	-
EC3.3 Hydrolases acting on ether bonds	GO:0016801	59.26	99.36	50	98.94	0.54	85.23	99.9	97.18	99.32	0.91	83.98	99.39	84.26	98.81	0.84
EC3.4 Hydrolases acting on peptide bonds (Peptidases)	GO:0008233	74.58	94.2	48.62	92.85	0.57	-	-	-	-	-	-	-	-	-	-
EC3.5 Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds	GO:0016810	60.47	97.78	54.17	96.23	0.56	-	-	-	-	-	-	-	-	-	-
EC3.6 Hydrolases acting on acid anhydrides	GO:0016817	91.6	95.57	75.74	95.05	0.81	-	-	-	-	-	-	-	-	-	-
EC3.7 Acting on carbon-carbon bonds	GO:0016822	96.48	99.89	94.56	99.82	0.95	91.19	99.91	95.19	99.74	0.93	84.4	99.43	78.03	99.07	0.81
EC3.8 Acting on halide bonds	GO:0016824	89.45	99.9	82.79	99.84	0.86	74.37	99.94	87.57	99.81	0.81	51.06	99.84	77.5	99.32	0.62
EC4.1 Carbon-carbon lyases	GO:0016830	89.82	89.35	83.9	89.53	0.78	-	-	-	-	-	-	-	-	-	-
EC4.2 Carbon-oxygen lyases	GO:0016835	80.4	92.24	80.8	88.82	0.73	-	-	-	-	-	-	-	-	-	-
EC4.3 Carbon-nitrogen lyases	GO:0016840	74.36	99.26	43.94	99.07	0.57	85.13	98.84	82.59	98	0.83	83.04	98.19	74.05	97.31	0.77
EC4.4 Carbon-sulfur lyases	GO:0016846	60.34	99.86	83.33	99.41	0.71	83.78	99.18	86.84	98.25	0.84	76.99	98.99	82.65	97.69	0.79
EC4.6 Phosphorus-oxygen lyases	GO:0016849	67.07	82.06	5.77	81.82	0.17	60.49	98.8	73.85	96.77	0.65	72.73	98.04	66.78	96.74	0.68
EC5.1 Racemases and Epimerases	GO:0016854	53.03	99.4	53.85	98.8	0.53	69.26	98.7	94.49	91.54	0.76	80.66	93.81	79.95	90.73	0.74
EC5.2 Cis-trans-Isomerases	GO:0016859	66.67	99.52	75	98.83	0.70	88.36	98.66	93.51	96.82	0.89	89.89	97.23	86.98	95.98	0.86
EC5.3 Intramolecular oxidoreductases	GO:0016860	75.84	98.02	57.69	97.26	0.65	-	-	-	-	-	-	-	-	-	-
EC5.4 Intramolecular transferases	GO:0016866	54.55	99.38	57.53	98.71	0.56	-	-	-	-	-	-	-	-	-	-
EC5.5 Intramolecular lyases	GO:0016872	70.09	99.03	60.48	98.42	0.64	75.39	99.86	82.59	99.65	0.79	62.36	99.83	76.69	99.48	0.69
EC5.99 Other Isomerases	GO:0016853	92.17	99.56	87.43	99.33	0.89	94.49	99.62	98.34	98.63	0.95	96.64	94.76	80.52	95.1	0.85
EC6.1 Ligases forming carbon-oxygen bonds	GO:0016875	90.79	97.32	91.37	95.76	0.88	-	-	-	-	-	-	-	-	-	-
EC6.2 Ligases forming carbon-sulfur bonds	GO:0016877	79.69	99.75	79.69	99.51	0.79	89.5	98.88	92.33	97.66	0.89	91.99	95.67	75.63	95.21	0.81
EC6.3 Ligases forming carbon-nitrogen bonds	GO:0016879	83.76	95.46	86.73	92.4	0.80	-	-	-	-	-	-	-	-	-	-
EC6.4 Ligases forming carbon-carbon bonds	GO:0016885	63.64	99.92	87.5	99.61	0.74	86.73	98.94	89.43	97.79	0.87	94.83	96.44	72.6	96.29	0.81
EC6.5 Ligases forming phosphoric ester bonds	GO:0016886	70.97	99.88	78.57	99.7	0.75	88.46	99.77	96.94	98.9	0.92	91.96	96.31	66.27	95.99	0.76
EC6.6 Forming nitrogen�metal bonds	GO:0051002	89.29	99.93	91.74	99.83	0.91	79.46	99.95	94.01	99.77	0.87	88.43	98.71	55.73	98.53	0.69
TC1.A alpha-type channels	GO:0005216	86.77	99.28	78.85	98.9	0.82	-	-	-	-	-	-	-	-	-	-
TC1.B beta-barrel porins	GO:0015288	70.65	99.6	69.15	99.23	0.69	-	-	-	-	-	-	-	-	-	-
TC1.C Pore-forming toxins (proteins and peptides)	GO:0005216	78.74	99.77	86.96	99.36	0.82	-	-	-	-	-	-	-	-	-	-
TC1.E Holins	GO:0034290	78.57	99.94	93.22	99.69	0.85	-	-	-	-	-	-	-	-	-	-
TC2.A porters (symporters, uniporters, antiporters)	GO:0015291	87.26	98.51	80.43	97.77	0.82	-	-	-	-	-	-	-	-	-	-
TC2.A.1 Major facilitator family (MFS)	GO:0005215	76.54	97.86	28.7	97.62	0.46	-	-	-	-	-	-	-	-	-	-
TC2.A.3 Amino acid-polyamine-organocation (APC) family	GO:0005215	93.94	99.36	40.26	99.34	0.62	-	-	-	-	-	-	-	-	-	-
TC2.A.6 Resistance-nodulation-cell division (RND) family	GO:0005215	71.88	99.41	34.85	99.28	0.50	-	-	-	-	-	-	-	-	-	-
TC2.C Ion-gradient-driven energizers	GO:0015291	76.47	99.79	87.5	99.35	0.81	-	-	-	-	-	-	-	-	-	-
TC3.A P-P-bond-hydrolysis-driven transporters	GO:0015405	78.68	97.63	86.25	94.62	0.79	-	-	-	-	-	-	-	-	-	-
TC3.A.1 ATP-binding cassette (ABC) family	GO:0043190	94.1	91.55	36.41	91.68	0.56	-	-	-	-	-	-	-	-	-	-
TC3.A.3 P-type ATPase (P-ATPase) family	GO:0015662	97.06	95.68	17.37	95.69	0.40	-	-	-	-	-	-	-	-	-	-
TC3.A.5 Type II (general) secretory pathway (IISP) family	GO:0015405	85.94	91.54	15.17	91.44	0.35	-	-	-	-	-	-	-	-	-	-
TC3.A.15 The Outer Membrane Protein Secreting Main Terminal Branch (MTB) family	GO:0015405	60.61	98.05	12.35	97.88	0.26	-	-	-	-	-	-	-	-	-	-
TC3.D Oxidoreduction-driven transporters	GO:0015453	91.14	99.5	94.49	98.79	0.92	-	-	-	-	-	-	-	-	-	-
TC3.E Light absorption-driven transporters	GO:0015454	96.11	99.85	97.29	99.65	0.96	-	-	-	-	-	-	-	-	-	-
TC4.A Phosphotransfer-driven group translocators	GO:0008982	82.7	99.66	87.93	99.16	0.85	-	-	-	-	-	-	-	-	-	-
TC9.A Recognized transporters of unknown biochemical mechanism	GO:0005215	78.79	99.3	75.14	98.76	0.76	-	-	-	-	-	-	-	-	-	-
TC9.B Putative uncharacterized transport proteins	GO:0005215	80.17	98.39	82.72	96.8	0.79	-	-	-	-	-	-	-	-	-	-
7 transmembrane receptor (rhodopsin family and chemoreceptor)	GO:0004930	96.9	99.16	97.33	98.62	0.96	-	-	-	-	-	-	-	-	-	-
7 transmembrane receptor (secretin family)	GO:0004930	90.7	94.91	24.02	94.84	0.45	-	-	-	-	-	-	-	-	-	-
7 transmembrane receptor (metabotropic glutamate family)	GO:0004930	89.86	95.77	16.76	95.72	0.37	-	-	-	-	-	-	-	-	-	-
7 transmembrane receptor (odorant receptor)	GO:0004930	97.44	97.56	17.59	97.56	0.41	-	-	-	-	-	-	-	-	-	-
G protein coupled receptors	GO:0004930	95.62	98.07	94.53	97.43	0.93	94.05	99.9	93.38	99.81	0.94	96.63	98.94	64.11	98.9	0.78
Nuclear receptors	GO:0003700	89.47	97.57	90.2	95.94	0.87	-	-	-	-	-	-	-	-	-	-
DNA-binding proteins	GO:0003677	90.4	85.56	77.77	87.29	0.74	68.97	98.06	85.19	94	0.73	81.86	90.19	61.38	88.85	0.65
RNA-binding proteins	GO:0003723	97.76	95.98	69.04	96.13	0.81	-	-	-	-	-	-	-	-	-	-
mRNA-binding proteins	GO:0003729	79.27	96.48	37.9	96.02	0.53	-	-	-	-	-	-	-	-	-	-
rRNA-binding proteins	GO:0019843	94.06	98.68	59.01	98.59	0.74	95.84	98.68	93.56	98.2	0.94	96.49	98.29	91.42	98.01	0.93
tRNA-binding proteins	GO:0000049	94.12	99.9	90.57	99.84	0.92	-	-	-	-	-	-	-	-	-	-
Structural proteins (Matrix protein,Core protein,Viral occlusion body,Keratin)	GO:0005198	98.46	99.19	98.49	98.93	0.97	-	-	-	-	-	-	-	-	-	-
Lectin	GO:0030246	81.63	85.7	5.31	85.66	0.17	-	-	-	-	-	-	-	-	-	-
Chlorophyll	GO:0016168	97.35	99.84	97.91	99.67	0.97	-	-	-	-	-	-	-	-	-	-
Photoreceptor	GO:0009881	92.88	99.62	95.47	99.09	0.94	80.77	99.98	91.3	99.94	0.86	61.17	99.78	41.72	99.68	0.50
DNA-directed DNA polymerase	GO:0003887	81.93	98.65	88.45	96.78	0.83	80.2	99.67	66.39	99.51	0.73	51.06	99.39	41.18	98.99	0.46
DNA-directed RNA polymerase	GO:0003899	88.95	97.95	93.48	95.72	0.88	-	-	-	-	-	-	-	-	-	-
Lipid-binding	GO:0008289	84.43	99.87	93.38	99.54	0.88	66.92	99.72	72.1	99.37	0.69	72.82	99.63	71.23	99.3	0.71
All lipid-binding proteins	GO:0008289	89.88	96.95	95.25	94.09	0.88	-	-	-	-	-	-	-	-	-	-
Calcium-binding	GO:0005509	86.26	88.22	57.04	87.92	0.63	-	-	-	-	-	-	-	-	-	-
Cobalt-binding	GO:0050897	81.63	99.91	98.09	98.93	0.89	-	-	-	-	-	-	-	-	-	-
Copper-binding	GO:0005507	83.51	98.11	72.76	97.28	0.77	-	-	-	-	-	-	-	-	-	-
Iron-binding	GO:0005506	93.96	91.37	64.86	91.74	0.73	-	-	-	-	-	-	-	-	-	-
Magnesium-binding	GO:0000287	81.16	87.9	80.91	85.29	0.69	-	-	-	-	-	-	-	-	-	-
Manganese-binding	GO:0030145	85.36	94.51	71.88	93.22	0.74	-	-	-	-	-	-	-	-	-	-
Nickel-binding	GO:0016151	77.61	99.18	70.59	98.64	0.73	-	-	-	-	-	-	-	-	-	-
Potassium-binding	GO:0030955	90.39	99.95	98.69	99.56	0.94	-	-	-	-	-	-	-	-	-	-
Sodium-binding	GO:0031402	90.91	99.86	97.39	99.37	0.94	-	-	-	-	-	-	-	-	-	-
Zinc-binding	GO:0008270	74.91	98.02	97.32	86.7	0.75	-	-	-	-	-	-	-	-	-	-
Metal-binding	GO:0046872	78.07	88.01	95.14	80.55	0.59	-	-	-	-	-	-	-	-	-	-
Actin binding	GO:0003779	94.94	99.45	83.25	99.33	0.88	-	-	-	-	-	-	-	-	-	-
Chitin-binding	GO:0008061	92.42	99.9	84.78	99.86	0.88	75.36	99.91	82.81	99.77	0.79	93.63	98.6	29.86	98.57	0.53
Folate-binding	GO:0005542	96.97	100	98.97	99.99	0.98	94.95	100	98.95	99.98	0.97	94.12	99.86	62.75	99.84	0.77
Antioxidant	GO:0016209	89	99.97	89.9	99.94	0.89	86	99.94	78.9	99.9	0.82	69.05	99.92	73.73	99.82	0.71
Calmodulin-binding	GO:0005516	87.2	99.96	90.51	99.9	0.89	82.93	99.93	83.95	99.85	0.83	69.96	99.44	41.6	99.27	0.54
Cyclin	GO:0061575	97.96	99.98	88.89	99.98	0.93	89.8	99.94	66.67	99.93	0.77	74.74	99.84	52.21	99.78	0.62
Cyclosporin	GO:0042277	87.5	100	100	99.99	0.93	75	99.99	80	99.98	0.77	84.21	99.93	35.56	99.92	0.55
Cytokine	GO:0005125	91.29	99.93	89.8	99.88	0.91	-	-	-	-	-	70.66	99.85	80	99.61	0.75
Elongation factor	GO:0003746	97.48	99.97	98.78	99.91	0.98	84.14	99.87	94.01	99.49	0.89	95.84	99.56	83.71	99.47	0.89
Excision nuclease	GO:0004518	97.39	99.99	99	99.97	0.98	93.46	99.93	91.37	99.87	0.92	95.75	99.48	58.84	99.45	0.75
Eye lens protein	GO:0005212	98	100	98	99.99	0.98	100	99.95	71.43	99.95	0.84	96.77	99.97	82.19	99.96	0.89
Growth factor	GO:0008083	88.89	99.92	88.52	99.85	0.89	86.01	99.91	86.72	99.82	0.86	76.74	99.87	81.91	99.7	0.79
GTPase activation	GO:0005096	92.92	99.94	83.33	99.92	0.88	86.73	99.93	78.4	99.89	0.82	61.84	99.56	42.24	99.36	0.51
Guanine-nucleotide releasing factor	GO:0005085	83.33	99.95	77.38	99.91	0.80	89.74	99.85	55.56	99.83	0.71	93.79	99.18	31.72	99.15	0.54
Heparin-binding	GO:0008201	89.13	99.92	73.87	99.89	0.81	90.22	99.86	61.03	99.83	0.74	70.73	99.93	75	99.84	0.73
Hormone	GO:0005179	87.69	99.92	90.68	99.81	0.89	76.88	99.9	87.97	99.7	0.82	69.78	99.83	80.45	99.52	0.75
Initiation factor	GO:0003743	91.36	99.86	93.02	99.7	0.92	74.21	99.93	95.41	99.43	0.84	77.63	99.65	81.18	99.22	0.79
Ion channel	GO:0005216	90.58	99.82	87.77	99.68	0.89	-	-	-	-	-	75.77	99.03	57.46	98.63	0.66
Metalloenzyme inhibitor	GO:0004857	83.33	99.99	93.75	99.98	0.88	88.89	99.98	80	99.97	0.84	70.73	99.96	63.04	99.93	0.67
Porin	GO:0015288	93.9	99.99	93.9	99.97	0.94	87.8	99.98	88.89	99.95	0.88	79.81	99.95	82.18	99.9	0.81
Protease inhibitor	GO:0030414	79.79	99.93	85.23	99.83	0.82	75.53	99.57	47.18	99.44	0.59	66.79	99.73	63.39	99.49	0.65
Protein phosphatase inhibitor	GO:0004864	96	99.99	88.89	99.99	0.92	-	-	-	-	-	64.86	99.99	88.89	99.96	0.76
SH3-binding	GO:0017124	94.12	99.99	95.52	99.98	0.95	-	-	-	-	-	58.16	99.92	65.52	99.82	0.62
Sigma factor	GO:0016987	87.04	99.98	85.45	99.96	0.86	83.33	99.97	81.82	99.95	0.82	68.33	99.9	50.62	99.85	0.59
Storage protein	GO:0045735	50	99.98	40	99.97	0.45	-	-	-	-	-	63.64	99.88	22.95	99.86	0.39
Vitamin C binding	GO:0031418	91.89	100	100	99.99	0.96	97.3	99.89	47.37	99.89	0.68	81.63	99.94	61.54	99.91	0.71
Zinc-finger	GO:0070742; GO:0071535	56.32	99.91	97.79	96.99	0.73	78.44	97.34	67.91	96.08	0.71	71.6	96.8	66.77	94.72	0.66
TC8.A Auxiliary transport proteins	GO:0006810	74.25	99.76	89.21	99.08	0.81	-	-	-	-	-	-	-	-	-	-
Cell adhesion	GO:0007155	85.93	99.11	84.06	98.43	0.84	-	-	-	-	-	-	-	-	-	-
Chlorophyll biosynthesis	GO:0015995	86.44	88.8	16.45	88.74	0.35	-	-	-	-	-	-	-	-	-	-
Herbicide resistance	GO:0009635	95.22	99.86	95.22	99.72	0.95	96.72	99.98	89.39	99.98	0.93	95.16	99.97	85.51	99.97	0.90
Photorespiration	GO:0009853	99.7	99.66	99.44	99.67	0.99	95.15	99.96	92.45	99.93	0.94	96.35	99.92	86.83	99.9	0.92
Photosynthesis	GO:0015979	93.3	98.06	82.28	97.64	0.87	81.62	99.64	87.88	99.09	0.84	86.21	99.36	81.3	98.94	0.83
Plant defense	GO:0006952	88.65	99.13	82.81	98.66	0.85	-	-	-	-	-	-	-	-	-	-
DNA condensation	GO:0030261	87.64	99.45	80.41	99.16	0.84	69.83	99.89	66.39	99.79	0.68	83.21	99.9	72.67	99.84	0.77
DNA integration	GO:0015074	86.63	98.07	87.05	96.58	0.85	72.79	99.96	87.61	99.86	0.80	68.92	99.85	63.75	99.74	0.66
DNA recombination	GO:0006310	85.74	97.38	92.05	94.34	0.85	77.59	98.92	76.95	97.96	0.76	67.46	99.25	80.3	97.87	0.73
DNA repair	GO:0006281	88.66	96.81	85.92	95.34	0.84	64.32	99.3	90.43	96.05	0.74	67.58	96.81	67.98	94.14	0.65
DNA replication	GO:0006260	85.6	96.64	76.77	95.37	0.79	76.78	98.9	77.64	97.85	0.76	59.69	98.5	66.57	96.65	0.62
Lipid degradation	GO:0016042	78.9	99.94	97.4	99.31	0.87	75.08	99.93	89.56	99.73	0.82	64.75	99.77	72.04	99.44	0.68
Lipid metabolism	GO:0006629	79.5	99.17	66.67	98.77	0.72	72.08	98.5	80.32	96.43	0.74	71.83	97.78	73.92	95.69	0.71
Lipid synthesis	GO:0008610	82.22	99.61	95.07	98.14	0.87	-	-	-	-	-	-	-	-	-	-
Lipid transport	GO:0006869	79.49	99.81	80.52	99.6	0.80	71.51	99.93	82.55	99.8	0.77	59.43	99.79	60.87	99.58	0.60
Lipopolysaccharide biosynthesis	GO:0009103	76.64	99.83	88.98	99.43	0.82	-	-	-	-	-	-	-	-	-	-
Lipoprotein	GO:0055097; GO:0055096	90.59	98.54	94.88	96.71	0.91	-	-	-	-	-	-	-	-	-	-
Immune response	GO:0006955	86.84	99.95	97.06	99.7	0.92	-	-	-	-	-	-	-	-	-	-
Inflammatory response	GO:0006954	87.5	99.75	73.68	99.65	0.80	75.37	99.69	46.98	99.6	0.59	55.21	99.81	59.22	99.6	0.57
Innate immunity	GO:0045087	89.66	99.9	86.67	99.82	0.88	65.52	99.93	85.88	99.71	0.75	84.64	99.24	49.74	99.12	0.65
Virulent protein	GO:0009405	95.38	99.92	96.49	99.82	0.96	70.3	99.92	87.65	99.66	0.78	63.98	99.14	49.15	98.69	0.56
mRNA capping	GO:0006370	80.77	99.85	79.25	99.72	0.80	82.19	99.97	91.6	99.9	0.87	61.54	99.72	46.83	99.57	0.54
mRNA slicing	-	77.27	99.3	77.27	98.65	0.77	-	-	-	-	-	-	-	-	-	-
Actin capping	GO:0051693	95.1	99.98	93.27	99.97	0.94	91.18	99.9	70.99	99.87	0.81	73.33	99.93	55	99.9	0.63
DNA replication inhibitor	GO:0008156	97.93	99.99	97.93	99.97	0.98	97.11	99.94	91.09	99.92	0.94	93.93	99.89	83.75	99.85	0.89
Mitogen	GO:0051781	92.74	99.93	93.24	99.86	0.93	83.6	99.92	91.2	99.75	0.87	85.19	99.77	79.59	99.62	0.82
Pathogenesis-related protein	GO:0009607	96.33	99.98	98.01	99.94	0.97	94.87	99.93	94.17	99.88	0.94	91.26	99.91	91.67	99.81	0.91
Protein synthesis inhibitor	GO:0017148	86.06	99.97	92.81	99.91	0.89	81.82	99.93	84.91	99.85	0.83	79.43	99.8	63.18	99.71	0.71
Vasoactive	GO:0050880	94.96	99.99	97.41	99.98	0.96	93.28	99.95	86.05	99.93	0.89	86.23	99.96	88.15	99.91	0.87
Amphibian defense peptide	GO:0006952	100	100	75	100	0.87	66.67	99.98	25	99.98	0.41	100	99.98	66.67	99.98	0.82
Chromatin regulator	GO:0016568	76.43	99.5	62.86	99.24	0.69	68.24	99.65	68.41	99.3	0.68	59.9	98.99	47.73	98.4	0.53
Chromophore	GO:0018298	93.83	99.93	93.83	99.87	0.94	86.91	99.87	88.44	99.73	0.88	89.38	99.49	68.2	99.37	0.77
Covalent protein-RNA linkage	GO:0018144	96.3	99.96	80	99.96	0.88	90.74	99.99	92.45	99.98	0.92	74.55	99.79	32.54	99.75	0.49
Hypotensive agent	GO:0008217	66.67	100	100	100	0.82	66.67	99.99	33.33	99.99	0.47	87.5	99.99	58.33	99.98	0.71
Integrin	GO:0007229	90.91	100	95.24	99.99	0.93	86.36	99.93	41.3	99.92	0.60	90.32	99.92	47.46	99.91	0.66
Motor protein	GO:0098840	89.47	99.97	91.07	99.94	0.90	80.7	99.95	82.88	99.89	0.82	64.32	99.46	39.03	99.27	0.50
Neuropeptide	GO:0007218	86.21	99.93	66.67	99.91	0.75	79.31	99.96	76.67	99.93	0.78	79.75	99.89	60	99.85	0.69
Signal transduction inhibitor	GO:0009968	84.62	99.91	49.25	99.89	0.65	84.62	99.98	80.49	99.96	0.82	87.04	99.94	65.28	99.92	0.75
Transmembrane	GO:0016021	90.12	86.66	79.06	87.9	0.75	-	-	-	-	-	-	-	-	-	-
Outer membrane	GO:0009279	92.71	86.42	32.12	86.83	0.50	-	-	-	-	-	-	-	-	-	-
Coat proteins	GO:0030117	84.77	99.41	85.2	98.85	0.84	-	-	-	-	-	-	-	-	-	-
Envelope proteins	GO:0019031	90	99.5	84.38	99.22	0.87	-	-	-	-	-	-	-	-	-	-
Photosystem I	GO:0009522	97.6	84.76	23.5	85.35	0.44	88.37	99.94	87.36	99.89	0.88	86.8	99.9	81.82	99.84	0.84
Photosystem II	GO:0009523	97.47	99.48	97.07	99.18	0.97	-	-	-	-	-	-	-	-	-	-
Collagen	GO:0005581	96.83	99.99	96.83	99.99	0.97	96.83	99.94	74.39	99.94	0.85	84.47	99.98	92.55	99.94	0.88
Flavoprotein	GO:0045251	87.93	99.36	88.02	98.78	0.87	73.73	99.54	89.55	98.24	0.81	71.3	97.81	64.25	96.43	0.66
Mutator protein	GO:1990633	83.82	100	98.28	99.97	0.91	77.94	99.91	62.35	99.87	0.70	70	99.95	73.13	99.9	0.71
Viral nucleoprotein	GO:0019013	89.91	99.95	91.93	99.89	0.91	87.72	99.98	96.15	99.9	0.92	79.06	99.87	77.73	99.74	0.78
cAMP binding	-	97.29	99.97	98.55	99.92	0.98	-	-	-	-	-	85.6	99.75	86.19	99.5	0.85
cGMP binding	-	98.46	100	98.46	99.99	0.98	-	-	-	-	-	82.19	99.79	41.96	99.76	0.58
Milk protein	-	92.16	100	97.92	99.99	0.95	-	-	-	-	-	74.07	99.98	86.96	99.95	0.80
Suppressor of RNA silencing	-	95.4	99.98	98.57	99.93	0.97	91.03	100	99.75	99.89	0.95	93.05	99.03	51.94	98.96	0.69
Allergen	-	85.19	99.88	60.53	99.84	0.71	86.42	99.92	69.31	99.89	0.77	74.11	99.95	79.81	99.87	0.77
Biotin binding	-	77.78	99.99	73.68	99.98	0.75	-	-	-	-	-	83.33	99.71	17.86	99.7	0.39
Cadmium binding	-	80	99.99	80	99.99	0.80	-	-	-	-	-	75	99.98	66.67	99.97	0.71
Chaperone	-	84.61	99.88	98.39	98.68	0.91	80.29	98.87	85.91	97.41	0.82	85.36	97.98	78.03	97	0.80
Chloride binding	-	92	99.98	92	99.96	0.92	-	-	-	-	-	71.64	99.85	62.34	99.76	0.66
Molybdenum binding	-	84.3	99.98	92.73	99.93	0.88	-	-	-	-	-	70.83	99.66	43.22	99.56	0.55
Muscle protein	-	95.38	99.96	90.51	99.95	0.93	89.23	99.91	77.33	99.87	0.83	79.77	99.89	76.67	99.81	0.78
Plastoquinone binding	-	96.7	99.98	98.65	99.94	0.97	-	-	-	-	-	93.46	99.76	82.03	99.69	0.87
Schiff base binding	-	93.2	99.86	93.56	99.73	0.93	-	-	-	-	-	73.3	99.7	83.4	99.17	0.77
Selenium binding	-	91.84	99.99	96.77	99.97	0.94	-	-	-	-	-	74	99.95	78.72	99.88	0.76
Sialic acid binding	-	76.19	100	94.12	99.98	0.85	90.48	99.9	35.19	99.9	0.57	81.82	99.96	64.29	99.95	0.73
Thiamine pyrophosphate binding	-	96.53	99.94	93.58	99.91	0.95	87.7	99.85	83.73	99.75	0.85	74.64	99.44	53.85	99.22	0.63
Ubiquinone binding	-	94.07	99.93	97.41	99.76	0.95	82.58	99.67	88.13	99.19	0.85	91.5	99.32	79.16	99.1	0.85
Last update: 29 Nov 2017