Weighted SIF Format
Weighted SIF format is defined based on SIF format, and it is useful when computing the properties for the edge-weighted networks.
The weighted SIF network format is tab-delimited. It specifies the two interacting nodes in each line, with the relationship type in between, and followed by the numerical edge weight:
(node A) tab (relationship type) tab (node B) tab (edge weight)
In biological networks, the edge weight could be PPI kinetics constant, PPI binding affinity, gene co-expression association, interaction confidence level, etc.
Additionally, the input file may contain multiple separated networks, PROFEAT automatically detects each connected network, ranks them by their number of nodes, and outputs descriptors for each individual network accordingly.
The sample edge-weighted SIF network file is available HERE.