SIF Network File Format
SIF format, namely Simple Interaction File is adopted in PROFEAT, and it is also compatiable with many network software (e.g. Cytoscape, Gephi, etc.)
The SIF network format is tab-delimited, specifying the two interacting nodes in each line, with the relationship type in between:
(node A) tab (relationship type) tab (node B)
Biologically, the binary interaction network could be protein-protein interaction network, gene co-expression network, gene regulatory network, drug-target network, metabolic network, etc.
Additionally, the input file may contain multiple separated networks, PROFEAT automatically detects each connected network, ranks them by their number of nodes, and outputs descriptors for each individual network accordingly.
The sample unweighted SIF network file is available HERE.