The Therapeutically Relevant
Multiple Pathways Database is designed to provide information about
such multiple pathways and related therpaeutic targets described in
the literatures, the targeted disease conditions, and the corresponding
drugs/ligands directed at each of these targets. This database currently
contains 11 entries of multiple pathways, 97 entries of individual pathways,
120 targets covering 72 disease conditions along with 120 sets of drugs
directed at each of these targets. Each entry can be retrieved through
multiple methods including multiple pathway name, individual pathway
name and disease name. Additional information provided include protein
name, synonyms, Swissprot AC number, species, gene name and location,
protein sequence (AASEQ) and gene sequence (NTSEQ) as well as potential
therapeutic implications while applicable. Cross-links to other databases
are provided which include Genecard, GDB, Locuslink, NCBI, KEGG, OMIM,
SwissProt to facilitate the access of more detailed information about
various aspects of the particular target or non-target protein.
Click
here
for the explanation of query method.
Click here
for the legend of the pathway map.
Click here
for the reference of all the pathways.
Note: all the pathways are developed using Macromedia Flash, an explorer plugin should be installed in order to view them.
Preliminary: Use of TRMP for commercial purposes is not allowed.
Citation: C.J.Zheng, H. Zhou, B. Xie, L.Y. Han, C.W. Yap, and Y. Z. Chen.(2004) TRMP: A Database of Therapeutically Relevant Multiple-Pathways, Bioinformatics. 20(14): 2236-41
Last update: 1/1/2004
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Dr.
Chen Yuzong
Associate Professor
Dept.Computational Science.NUS.
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