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| Therapeutic Target Database |
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Therapeutic Target Database (TTD) is a database
to provide information about the known and explored therapeutic
protein and nucleic acid targets, the targeted disease, pathway
information and the corresponding drugs directed at each of these
targets. Also included in this database are links to relevant
databases containing information about target function, sequence,
3D structure, ligand binding properties, enzyme nomenclature and
drug structure, therapeutic class, clinical development status.
All information provided are fully referenced.
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| NEWS |
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TTD
Version 4.3.02 release on Aug 25th 2011. New version
of TTD provides Quantitative
Structure-Activity Relationship (QSAR) models
and Target
Validation Information for TTD drug target.
Moreover, Multi
Target Agents Data with structure and potency
information, Drug
Combinations and Nature-derived
Drugs together with drug species origin data
are also included.
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Statistics
of this database |
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This
database currently contains 2,025
targets, including 364
successful, 286 clinical
trial, 44 discontinued
and 1,331 research targets,
17,816
drugs, including 1,540
approved, 1,423 clinical
trial, 14,853 experimental
drugs and 3,681
multi-target agents (14,170
small molecules and 652
antisense drugs with available strucuture or oligonucleotide sequence).
Targets
and drugs in this database cover 61
protein biochemical class and 140
drug therapeutic classes respectively.
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How
to cite our database |
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Y. Zhou, ......, Y. Z. Chen*, F. Zhu*. TTD: Therapeutic Target Database describing target druggability information.
Nucleic
Acids Res.
doi: 10.1093/nar/gkad751 (2023).
PubMed
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Welcome
to sign our Guestbook.
If you
find any error in data or bug in web service, please kindly report it
to Dr.
Zhu.
Dr.
Chen Yuzong
Deputy
Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
All rights
reserved.
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