PROFEAT - Protein Feature Server (2016)                                                                                        Return to HOME

PROFEAT is a web server for computing commonly used proteins features from amino acid sequence, and interaction network properties from network structure.

🔑 Reference Manual and User Guide
🔑 Network Descriptor Tutorial NEW!
🔑 Structure Descriptor Tutorial NEW!

Protein-Protein Interaction Pair Descriptors

upload your protein pair,             or upload sample protein pair

You can EITHER give

protein-protein interaction pair SEPARATELY here:

Sequence A

Sequence B

Sequence MUST be provided in RAW or FASTA format


PPI pairs by upload sequence and PPI pair files here:

Upload Sequences

File format of Sequences can be found HERE

Upload PPI Pairs

File format of PPI Pairs can be found HERE

Length of protein name is restricted to <100 characters

How to cite our database

P. Zhang, L. Tao, X. Zeng, C. Qin, S.Y. Chen, F. Zhu, Z.R. Li, Y.Y. Jiang, W.P. Chen, Y.Z. Chen. A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks. Brief Bioinform. pii: bbw071 (2016).

P. Zhang, L. Tao, X. Zeng, C. Qin, S.Y. Chen, F. Zhu, S.Y. Yang, Z.R. Li, W.P. Chen, Y.Z. Chen. PROFEAT Update: A Protein Features Web Server with Added Facility to Compute Network Descriptors for Studying Omics-Derived Networks. J Mol Biol. pii:S0022-2836(16)30428-4. (2016).

H.B. Rao, F. Zhu, G.B. Yang, Z.R. Li, and Y.Z. Chen. Update of PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence. Nucleic Acids Res. Jul 1, 2011; 39(Web Server issue):W385-90.

Z.R. Li, H.H. Lin, L.Y. Han, L. Jiang, X. Chen, and Y.Z. Chen. PROFEAT: A Web Server for Computing Structural and Physicochemical Features of Proteins and Peptides from Amino Acid Sequence. Nucleic Acids Res. Jul 1, 2006; 34(Web Server issue):W32-7.

List of Publications That Used the Features in PROFEAT

The earlier version of PROFEAT can be found HERE.

Last updated: 30 May 2016

visits since November 6, 2005

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Tao Lin or Mr. Zhang Peng.

Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD |  Databases |  Software |  Teaching |  Research |  Links

     Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543