TCM Prescription: He Shou Wu Granules



Prescription Description
Prescription IDTCMFx6817
Pinyin NameHe Shou Wu Ke Li
Chinese Name何首乌颗粒
English NameHe Shou Wu Granules
Function Description血劳, 眩晕, 耳鸣, 白发症, 崩漏
IndicationsMetrorrhagia disorder, Tinnitus disorder, Vertigo disorder, Abnormal uterine and vaginal bleeding, Tinnitus, Dizziness, Anemia
Disease ICD-11 Category SB93 [Metrorrhagia disorder (TM1), 崩漏 (TM1) ];
SC75 [Tinnitus disorder (TM1), 耳鸣 (TM1) ];
SD22 [Vertigo disorder (TM1), 眩晕 (TM1) ];
GA2Z [Abnormal uterine or vaginal bleeding, unspecified, 异常子宫或阴道出血,未特指的 ];
MC41 [Tinnitus, 耳鸣 ];
MB48 [Dizziness and giddiness, 头晕和眩晕 ];
MB21.1 [Amnesia, 健忘症 ];
Human Tissues Associated with IndicationBrain
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH819 Polygonum multiflorum 何首乌 TCMH819 ITSAL419-14
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT329 NQO2 Quinone reductase 2 Oxidoreductase P16083
TCMT729 PIK3CA PI3-kinase p110-alpha subunit Transferase P42336
TCMT730 PIK3CB PI3-kinase p110-beta subunit Transferase P42338
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1170 Enterobacter cloacae
TCMT1176 Streptococcus pneumoniae
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1182 Streptococcus sanguinis
TCMT1213 Neisseria gonorrhoeae
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
Select to Download
1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway