Prescription Description
| Prescription ID | TCMFx6448 |
| Pinyin Name | Zhi Ke Ding Chuan Pian |
| Chinese Name | 止咳定喘片 |
| English Name | Zhi Ke Ding Chuan Tablets |
| Function Description | 哮喘 |
| Indications | Asthma |
| Disease ICD-11 Category |
CA23 [Asthma, 哮喘
]; |
| Human Tissues Associated with Indication | Lung |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH118 | Angelica dahurica | 白芷 | TCMH118 | ITSAK3312-14 |
| TCMH899 | Damnacanthus indicus | 虎刺 | TCMH899 | ITSAO999-14 |
| TCMH6 | Ardisiae japonicae | 矮地茶 | TCMH6 | |
| TCMH1370 | Siraitia grosvenorii | 罗汉果 | TCMH1370 | ITSAL2179-14 |
| TCMH2000 | Tacca plantaginea | 水三七 | TCMH2000 | ITSAN589-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT378 | LIMK1 | LIM domain kinase 1 | Kinase | P53667 |
| TCMT613 | NR3C1 | Glucocorticoid receptor | Nuclear receptor | P04150 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1180 | Human herpesvirus 2 |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1247 | Human herpesvirus 1 |
| TCMT1250 | Vesicular stomatitis virus |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1294 | Human parainfluenza virus 3 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1444 | Fusarium oxysporum |
| TCMT1447 | Respiratory syncytial virus |
| TCMT1449 | Influenza A virus |
| TCMT1450 | Plasmodium falciparum 3D7 |
| TCMT1451 | Sclerotinia |
| TCMT1452 | Rhizopus microsporus var. chinensis |
| TCMT1453 | Penicillium crustosum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples