Prescription Description
| Prescription ID | TCMFx5283 |
| Pinyin Name | She Xiang Zhi Chuang Shuan |
| Chinese Name | 麝香痔疮栓 |
| English Name | She Xiang Zhi Chuang Shuan |
| Function Description | 痔疮, 肛裂 |
| Indications | Fissured anus disorder, Anal fissure, Hemorrhoids |
| Disease ICD-11 Category |
SB7C [Fissured anus disorder (TM1), 肛裂 (TM1)
]; DB50.0 [Anal fissure, 肛裂 ]; DB60 [Haemorrhoids, 痔 ]; |
| Human Tissues Associated with Indication | Large Intestine |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1886 | NA | 麝香酮 | TCMH1886 | |
| TCMH1716 | Calculus bovis artificiosus | 人工牛黄 | TCMH1716 | |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
| TCMH1768 | Panax notoginseng | 三七 | TCMH1768 | ITSAO2360-14 |
| TCMH2175 | Galla chinensis | 五倍子 | TCMH2175 | |
| TCMH1337 | Calamina | 炉甘石 | TCMH1337 | |
| TCMH472 | Atropa belladonna | 颠茄流浸膏 | TCMH472 | AY028147 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT290 | CHRM5 | Muscarinic acetylcholine receptor M5 | GPCR | P08912 |
| TCMT291 | CHRM3 | Muscarinic acetylcholine receptor M3 | GPCR | P20309 |
| TCMT292 | CHRM1 | Muscarinic acetylcholine receptor M1 | GPCR | P11229 |
| TCMT293 | CHRM2 | Muscarinic acetylcholine receptor M2 | GPCR | P08172 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
| TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1218 | Staphylococcus aureus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1393 | Vibrio sp. |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples