Prescription Description
| Prescription ID | TCMFx4878 |
| Pinyin Name | Luo Fu Shan Liang Cha Ke Li |
| Chinese Name | 罗浮山凉茶颗粒 |
| English Name | Luo Fu Shan Liang Cha Granules |
| Function Description | 中暑, 感冒, 积滞 |
| Indications | Common cold disorder, Common cold, Dyspepsia, Sunstroke |
| Disease ICD-11 Category |
SA60 [Common cold disorder (TM1), 感冒 (TM1)
]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; MD92 [Dyspepsia, 消化不良 ]; NF01.0 [Heat stroke, 中暑 ]; |
| Human Tissues Associated with Indication | Lung, Blood, Spleen, Intestine, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH667 | Radix ilicis asprellae | 岗梅 | TCMH667 | |
| TCMH442 | Elephantopus scaber | 地胆草 | TCMH442 | ITSAF3392-14 |
| TCMH910 | Tadehagi triquetrum | 葫芦茶 | TCMH910 | ITSAJ4186-14 |
| TCMH1136 | Bidens biternata | 金盏银盘 | TCMH1136 | GENG996-15 |
| TCMH90 | Imperata cylindrica | 白茅根 | TCMH90 | ITSAP888-14 |
| TCMH420 | Lophatherum gracile | 淡竹叶 | TCMH420 | GBVY2724-14, GBVT2442-13 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT49 | SCN9A | Sodium channel protein type IX alpha subunit | Ion channel | Q15858 |
| TCMT51 | SCN11A | Sodium channel protein type XI alpha subunit | Ion channel | Q9UI33 |
| TCMT52 | SCN8A | Sodium channel protein type VIII alpha subunit | Ion channel | Q9UQD0 |
| TCMT53 | SCN4A | Sodium channel protein type IV alpha subunit | Ion channel | P35499 |
| TCMT54 | SCN3A | Sodium channel protein type III alpha subunit | Ion channel | Q9NY46 |
| TCMT55 | SCN2A | Sodium channel protein type II alpha subunit | Ion channel | Q99250 |
| TCMT56 | SCN1A | Sodium channel protein type I alpha subunit | Ion channel | P35498 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1212 | Verticillium dahliae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1221 | Human herpesvirus 4 |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1229 | Enterococcus faecalis |
| TCMT1231 | Human herpesvirus 1 strain KOS |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1346 | Helicobacter pylori |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples