Prescription Description
| Prescription ID | TCMFx4340 |
| Pinyin Name | Nong Suo Shui Niu Jiao Pian |
| Chinese Name | 浓缩水牛角片 |
| English Name | Nong Suo Shui Niu Jiao Tablets |
| Function Description | 温毒发斑, 急惊风, 癫痫, 狂病 |
| Indications | Acute convulsion disorder, Convulsions, Epilepsy |
| Disease ICD-11 Category |
SE33 [Acute convulsion disorder (TM1), 急惊风 (TM1)
]; 8A68.Z [Type of seizure, unspecified, 癫痫发作类型，未特指的 ]; 8A6Z [Epilepsy or seizures, unspecified, 癫痫或癫痫发作，未特指的 ]; |
| Human Tissues Associated with Indication | Brain, Heart |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1997 | Bubalus bubalis | 水牛角 | TCMH1997 | GBMA0080-06 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT243 | ADRA2C | Alpha-2c adrenergic receptor | GPCR | P18825 |
| TCMT247 | ADRA2A | Alpha-2a adrenergic receptor | GPCR | P08913 |
| TCMT273 | NR1H4 | Bile acid receptor FXR | Nuclear receptor | Q96RI1 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT588 | DAO | D-amino-acid oxidase | Oxidoreductase | P14920 |
| TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
| TCMT796 | PCNA | Proliferating cell nuclear antigen | Unclassified | P12004 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
| TCMT864 | THRA | Thyroid hormone receptor alpha | Nuclear receptor | P10827 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1177 | Haemophilus influenzae |
| TCMT1193 | Staphylococcus |
| TCMT1194 | Shigella sonnei |
| TCMT1195 | Streptococcus pasteurianus |
| TCMT1196 | Salmonella |
| TCMT1197 | Shigella sp. |
| TCMT1198 | Serratia marcescens |
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1227 | Streptococcus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1243 | Aspergillus flavus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1361 | Neisseria meningitidis |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1412 | Salmonella typhimurium |
| TCMT1442 | Leishmania donovani |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1454 | Bacillus subtilis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples