Prescription Description
| Prescription ID | TCMFx3790 |
| Pinyin Name | Fu Fang Man Tuo Luo Yao Shui |
| Chinese Name | 复方曼陀罗药水 |
| English Name | Fu Fang Man Tuo Luo Yao Decoction |
| Function Description | 腹痛, 跌打损伤, 痹病 |
| Indications | Abdominal pain disorder, Arthritis |
| Disease ICD-11 Category |
SA58 [Abdominal pain disorder (TM1), 腹痛 (TM1)
]; FA2Z [Inflammatory arthropathies, unspecified, 炎性关节病，未特指的 ]; |
| Human Tissues Associated with Indication | Intestine, Stomach, SkeletalMuscle |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1442 | Datura stramonium | 曼陀罗 | TCMH1442 | ITSAM3630-14 |
| TCMH222 | Aconitum carmichaelii | 草乌 | TCMH222 | ITSAH2410-14 |
| TCMH1228 | Capsicum frutescens | 辣椒 | TCMH1228 | ITSAL4555-14 |
| TCMH2585 | Cinnamomum camphora | 樟脑 | TCMH2585 | SDH069-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT154 | PRKCD | Protein kinase C delta | Kinase | Q05655 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT290 | CHRM5 | Muscarinic acetylcholine receptor M5 | GPCR | P08912 |
| TCMT291 | CHRM3 | Muscarinic acetylcholine receptor M3 | GPCR | P20309 |
| TCMT292 | CHRM1 | Muscarinic acetylcholine receptor M1 | GPCR | P11229 |
| TCMT293 | CHRM2 | Muscarinic acetylcholine receptor M2 | GPCR | P08172 |
| TCMT327 | TRPV1 | Vanilloid receptor | Ion channel | Q8NER1 |
| TCMT551 | CHRM4 | Muscarinic acetylcholine receptor M4 | GPCR | P08173 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1212 | Verticillium dahliae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1221 | Human herpesvirus 4 |
| TCMT1246 | Escherichia coli |
| TCMT1247 | Human herpesvirus 1 |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1438 | Plasmodium falciparum |
| TCMT1444 | Fusarium oxysporum |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples