GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, GSK3B, HSD17B2, IDO1, IGF1R, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC, TYR |
8.13537 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, MMP2, NR3C1, PTGS2, RORC, SRC, TYR |
7.21333 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
6.89455 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FUT7, IDO1, PIM1, PTGS2, TYR, XDH |
6.8627 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, HSD17B1, HSD17B2, MET, PTGS2 |
6.8627 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CDC25B, CSNK2A1, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PGR, PIM1, PTGS2, SRC, XDH |
6.43788 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
6.43788 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
6.43788 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, IDO1, NR3C1, PTGS2, RORC, SRC, TYR |
6.43788 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC, TYR |
6.43788 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
6.39345 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
6.33068 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, DHFR |
6.30994 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
6.29661 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, GSK3B, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
6.29661 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
6.28835 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
5.978 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP2, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
5.978 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
5.9236 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7 |
5.91723 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MMP9, PTGS2, SRC |
5.88397 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC |
5.74743 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
5.74743 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APP, AR, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, NR3C1, PTGS2, RORC, SRC, TYR |
5.70842 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, TYR |
5.5928 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, GSK3B, IDO1, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
5.20482 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1, HSD17B2 |
5.09522 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC |
5.06389 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, HSD17B1, HSD17B2, KDR, MET, PTGS2, SRC, XDH |
4.83085 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, FUT7, GSK3B, HSD17B2, KDR, MET, MMP2, MMP9, PGR, PIM1, PTGS2, RORC, SRC, TYR |
4.79053 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
4.72555 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, PIM1, SRC |
4.71135 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, APP, AR, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, NR3C1, PTGS2, RORC, SRC |
4.71135 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CYP1B1, GSK3B, IGF1R, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC |
4.68483 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
4.25703 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APP, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, GSK3B, IGF1R, MMP2, NR3C1, PTGS2, SRC |
4.25703 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, APP, AR, AURKB, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, NR3C1, PTGS2, PTPN1, RORC, SRC |
4.1565 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, GSK3B, IDO1, KDR, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
4.14565 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
4.11718 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
4.07006 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APP, AR, CYP1A1, CYP1B1, FLT3, NR3C1, PTGS2, RORC, SRC |
3.99059 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD17B2, KDR, MMP9, PGR, PIM1, PTGS2, RORC, SRC, TYR |
3.97673 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
3.97673 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
3.97673 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.89436 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.83859 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.79349 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, NR3C1, PTGS2, PTPN1, RORC, SRC, TYR |
3.77092 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
3.65022 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, HCAR2, IDO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
3.64369 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MET, PTGS2 |
3.64253 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, GSK3B, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC |
3.60484 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CYP1B1, FLT3, KDR, MET, PTGS2, PTPN1, SRC, XDH |
3.59451 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
3.58285 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
3.57667 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, FABP4, GSK3B, IGF1R, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
3.53471 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, RORC, SRC |
3.5236 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AXL, CYP19A1, CYP1A2, CYP1B1, FABP4, HSD17B2, IDO1, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, RORC, SRC, TYR |
3.51631 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
3.351 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.34618 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.28417 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, CDC25B, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2 |
3.28083 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, DHFR, FABP4, GSK3B, IDO1, IGF1R, MET, MMP12, MMP2, PTGS2, PTPN1, SRC, XDH |
3.16203 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
3.13765 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC, TYR |
3.11538 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
3.06487 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC |
3.06487 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HCAR2, PTGS2, RORC, SRC |
3.03191 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, RORC, SRC |
2.98586 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CSNK2A1, DHFR, FABP4, GSK3B, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.98586 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.98586 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, APP, AURKB, AXL, CDC25B, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
2.98586 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
2.9852 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HCAR2, HSD17B1, HSD17B2 |
2.92384 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.91398 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, NR3C1, PGR, PIM1, RORC, SRC |
2.91398 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, APP, AR, AXL, CDC25B, CYP19A1, CYP1A1, HSD17B2, IDO1, MMP2, MMP9, PGR, PTGS2, SRC |
2.91398 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
2.91076 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, NR3C1, PTGS2, SRC |
2.90569 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC, TYR |
2.8854 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC |
2.87943 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B2, KDR, SRC, TYR |
2.85053 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, DHFR, IDO1 |
2.84506 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, DHFR, FABP3, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.83479 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, NR3C1, PTGS2, SRC |
2.83479 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.81244 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APP, AR, FLT3, GSK3B, IGF1R, MMP2, NR3C1, PTGS2, SRC |
2.81244 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, APP, AURKB, AXL, CDC25B, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
2.80506 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.80506 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.79031 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
2.7569 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, DHFR, TYR |
2.74505 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, PTGS2 |
2.7342 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.63044 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC |
2.63044 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.63044 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC |
2.62389 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, GSK3B, MET, MMP9, SRC |
2.62389 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, PTGS2 |
2.60617 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, APP, AR, AXL, CBR1, CDC25B, CYP1A1, FABP4, FLT3, FUT7, GSK3B, KDR, MET, MMP2, MMP9, PGR, PTGS2, RORC, SRC |
2.59797 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CYP1A1, CYP1B1, DHFR, FABP3, KDR, NR3C1, PTGS2, SRC |
2.58949 |
[BP] GO:0010038 |
response to metal ion
|
APP, CA2, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.56092 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.5507 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FLT3, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.53732 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FLT3, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.53732 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD17B1, HSD17B2 |
2.53732 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AR, AURKB, AXL, CDC25B, CSNK2A1, CYP1A1, CYP1A2, DHFR, FLT3, FUT7, GSK3B, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
2.53732 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.53732 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.52362 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.52362 |
[BP] GO:0048545 |
response to steroid hormone
|
AR, CA2, FLT3, NR3C1, PTGS2, SRC |
2.50409 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.50409 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.50409 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, CA2, CYP1B1, HCAR2, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SRC |
2.45567 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.45319 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, FLT3, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.4492 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
2.44366 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APP, AXL, CYP1B1, MMP9, PTGS2, SRC |
2.41293 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, GSK3B, IDO1, XDH |
2.41293 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, HCAR2, KDR, PTGS2, SRC |
2.41293 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
2.41293 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.41008 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, CA2, CYP19A1, GSK3B, HCAR2, MMP12, PTGS2, SRC |
2.40077 |
[BP] GO:0032787 |
None
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, PTGS2 |
2.40073 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.40073 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
2.40072 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APP, FABP3, GSK3B, IGF1R, PTGS2, SRC |
2.3896 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, IDO1 |
2.3896 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.37194 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, FABP3, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.35982 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.33228 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, FABP4, FLT3, IGF1R, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.33228 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, FLT3, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.32683 |
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, GSK3B, HCAR2, MMP12, PTGS2, PTPN1, SRC |
2.32322 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, CDC25B, CSNK2A1, DHFR, FABP4, FLT3, GSK3B, IGF1R, MMP9, PTGS2, PTPN1, SRC, XDH |
2.31888 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.31888 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.30853 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.30853 |
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.30731 |
[BP] GO:0071383 |
None
|
AR, FLT3, NR3C1, SRC |
2.30556 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, CYP1A1, FLT3, MET, PIM1, SRC, TYR |
2.303 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2 |
2.26727 |
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.26049 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, APP, AR, FLT3, KDR, PTPN1, SRC, XDH |
2.26049 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, NR3C1, PGR, SRC |
2.23249 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
2.2181 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.21547 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, NR3C1, SRC |
2.17984 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.17984 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, NR3C1, NR3C2, PGR, RORC |
2.1793 |
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, IDO1 |
2.16582 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.16147 |
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HCAR2, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
2.16147 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, PTGS2 |
2.15223 |
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.15223 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC |
2.13229 |
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, CYP1B1, FABP3, IDO1, PTGS2, XDH |
2.10908 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.10268 |
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APP, AR, AURKB, CSNK2A1, DHFR, FABP4, GSK3B, IGF1R, KDR, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.08466 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.08466 |
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CYP1A1, PGR, PTGS2, SRC |
2.08466 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.08466 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, HSD17B1, HSD17B2, PTGS2 |
2.07158 |
[BP] GO:0021700 |
developmental maturation
|
APP, AXL, CDC25B, MMP2, PGR |
2.06995 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.06995 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
2.06342 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, APP, AR, FLT3, IGF1R, KDR, PTPN1, SRC, XDH |
2.06237 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
2.05464 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.05454 |
[BP] GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, MMP9, PTGS2, SRC |
2.05311 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, FABP4, FLT3, IGF1R, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.04925 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, GSK3B, PGR, RORC, SRC |
2.04578 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.02785 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, FABP3 |
2.02072 |
[BP] GO:1901654 |
None
|
AKR1B1, AR, CSNK2A1, NR3C1, SRC |
2.02017 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.0003 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, CA1, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, KDR, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
2.86919 |
[CC] GO:0005829 |
cytosol
|
AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, CA1, CA2, CA7, CBR1, CDC25B, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, NR3C1, NR3C2, PGR, PIM1, PTPN1, SRC, TYR, XDH |
2.69385 |
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.01192 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.81515 |
[CC] GO:0005783 |
None
|
ADORA1, APP, CA4, CYP19A1, FLT3, KDR, PTGS2, PTPN1, XDH |
1.41376 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTPN1, RORC, TYR, XDH |
12.4348 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
8.45412 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
8.22903 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
8.22903 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
6.42159 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA7, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PTPN1, RORC |
5.978 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
5.40325 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
4.76212 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, PTGS2, SRC |
4.71135 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
4.70682 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, PTGS2, SRC |
4.51577 |
[MF] GO:0005496 |
steroid binding
|
AR, HSD17B1, NR3C1, NR3C2, PGR, RORC |
4.38597 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
4.38597 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.89504 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, HSD17B1, IDO1, PTGS2, SRC, XDH |
3.87807 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, NR3C1, NR3C2, PGR, RORC |
3.82458 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.73618 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.72619 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2, XDH |
3.42028 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.29877 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, HSD17B1, IGF1R, NR3C1 |
3.16203 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS2, TYR |
3.13765 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, XDH |
3.06781 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
3.01239 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
2.98586 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.92384 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.91963 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.85637 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
2.83479 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.80506 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2 |
2.63044 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.41252 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, FLT3, HCAR2, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, RORC |
2.34661 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PTPN1, SRC |
2.33228 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.303 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.26049 |
[MF] GO:0008289 |
lipid binding
|
AR, AXL, FABP3, FABP4, HSD17B1, NR3C1, NR3C2, PGR, RORC |
2.21286 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.17432 |
[MF] GO:0005158 |
None
|
IGF1R, PTPN1, SRC |
2.11325 |
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, KDR, NR3C1 |
2.08466 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.01192 |