| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
15.7992 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CHRM1, CHRM3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TRPV1, XDH |
15.7992 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA3, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, HSD17B2, HSP90AB1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
15.051 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
13.4619 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
13.345 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
13.3187 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
13.2795 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, HSP90AB1, NR3C1, PPARG, PRKCE, PRKCG, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
13.0767 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, HSD11B1, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PPARG, PTGS1, PTGS2, TRPV1 |
12.6483 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.3617 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FLT3, GPR35, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.9615 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TOP2A, TYR, XDH |
11.7738 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.5769 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.4165 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.2636 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CHRM1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, GPR35, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
11.0214 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.8283 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.7675 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.7557 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, FABP3, FUT7, GLO1, HSPA1A, PIK3CA, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR, XDH |
10.7438 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, ALOX12, APP, BCL2, CDC25B, CHRM1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F2, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARG, PRKCA, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
10.6233 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, PPARG, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
10.4451 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CHRM1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
10.2814 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F2, F3, FLT3, GPR35, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.2055 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, IGF1R, INSR, MMP2, NR3C1, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
10.142 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.0386 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
9.96442 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
9.91585 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPR35, HSP90AA1, HSP90AB1, INSR, MET, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCE, SMAD3, SRC, TRPV1 |
9.85796 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F2, F3, FABP4, FLT3, GPR35, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.81811 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, INSR, NR3C1, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
9.64798 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
9.62602 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSP90AB1, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
9.57992 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
9.42436 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CHRM2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F2, F3, FABP3, FABP4, FLT3, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR |
9.42148 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.92571 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.91177 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
8.91177 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
8.81708 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, FABP3, HSP90AB1, KDR, NR3C1, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
8.75806 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
8.71081 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.65404 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.64325 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CHRM5, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, HSP90AB1, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.59858 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, PPARG, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.56421 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
8.54402 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
8.54402 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CHRM5, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, HSP90AB1, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.53981 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, HSP90AB1, IGF1R, INSR, MMP2, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
8.53981 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CHRM1, CYP19A1, DRD1, DRD2, DRD3, EGFR, F2, GPR35, HCAR2, HSP90AB1, HSPA1A, INSR, MMP12, MMP9, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
8.53981 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.52783 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ALOX12, APP, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.46867 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
8.46427 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, F2, FABP3, FLT3, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.41926 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, F2, FABP3, FLT3, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.41926 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.39641 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, FABP4, GPR35, INSR, MET, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCE, SMAD3, TRPV1 |
8.31647 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
8.30184 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX12, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUT7, MET, PIK3CA, PIK3CB, PPARA, PPARG, PTGS1, PTGS2 |
8.13671 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
8.06985 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
8.06562 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HSD11B1, HSD17B1, HSD17B2, NQO2, PPARG, PTGS1, PTGS2, TYR, XDH |
8.01722 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PRKCD, PTGS2, SRC |
8.01523 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
7.99175 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, HSP90AB1, IGF1R, INSR, MMP2, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
7.98144 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, HSP90AA1, HSP90AB1, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
7.92859 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.91051 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, HSP90AB1, NR3C1, PPARG, PTGS2, RORC, SRC, TRPV1 |
7.91051 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CYP1B1, DRD1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
7.897 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, XDH |
7.88373 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CHRM1, CHRM3, CHRM5, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F2, F3, FABP4, HSD17B2, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
7.88106 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, HSP90AA1, HSP90AB1, HSPA1A, MMP2, PPARA, PPARG, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
7.85615 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.7521 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CHRM5, CYP1A1, DRD3, F2, FABP3, FLT3, HCAR2, PPARA, PPARG, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
7.73444 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.71134 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A, TYR |
7.71134 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.71134 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.6974 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CBR1, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
7.69298 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, HSP90AA1, HSP90AB1, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
7.6767 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F2, F3, FABP4, KDR, MET, MMP12, PPARA, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
7.63624 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX12, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F2, F3, FABP4, FLT3, GPR35, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.58885 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
7.56351 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, DRD1, DRD2, DRD3, EGFR, F2, HCAR2, HSP90AB1, INSR, MMP12, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
7.49707 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD17B2, NR3C1, PPARG, PRKCE, PTGS2, RORC, SRC, TYR |
7.49707 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, ALOX12, BCL2, CDC25B, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F2, F3, FLT3, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK |
7.452 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, ESRRB, F2, FLT3, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.28216 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, DRD1, EGFR, HSP90AB1, KDR, NR3C1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
7.25517 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, F2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
7.18296 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, HSP90AA1, KDR, PRKCD, PRKCE, SRC |
7.16624 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ALOX12, APP, AXL, BCL2, CA2, CHRM1, CHRM2, CHRM3, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, GPR35, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1, XDH |
7.11345 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CBR1, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
7.11215 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, DRD1, DRD2, DRD3, EGFR, F2, HCAR2, KDR, PIK3CB, PRKCE, PTGS2, SRC, TRPV1 |
7.04461 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
7.02783 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PPARG, PTGS1, PTGS2 |
7.01118 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, F2, FABP4, FLT3, HSP90AB1, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.00402 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
6.95848 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
6.95718 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, ESR1, HSD11B1, HSD17B1, HSD17B2 |
6.95358 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, F2, FLT3, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.9452 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.90472 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, F2, FLT3, FUT7, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
6.84504 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ALOX12, APP, AXL, BCL2, CA2, CHRM3, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F2, F3, HCAR2, HSPA1A, KDR, MET, MMP12, MMP9, PIM1, PPARG, PRKCA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
6.83726 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, F2, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A |
6.81386 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SRC, TEK |
6.77289 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, F2, KDR, PRKCE, SRC, TRPV1 |
6.75966 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.75965 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.75599 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, F2, HSP90AA1, HSP90AB1, HSPA1A, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
6.74829 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FABP4, FLT3, GPR35, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1, XDH |
6.74013 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
6.71695 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HCAR2, HSD11B1, HSD17B1, HSD17B2, PRKCA, PRKCE, SLC22A1 |
6.66939 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HSP90AB1, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.55588 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
6.55523 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
6.55523 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, PIK3CA, PPARA, PPARG, SMAD3, SRC, TEK, TYR |
6.54307 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX12, ALOX15, BCL2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.53416 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
6.42635 |
|
[BP] GO:0015872 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
6.36951 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, ALOX12, CHRM1, CHRM3, DRD2, F10, F2, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
6.36951 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F2, F3, FLT3, HSP90AB1, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.36951 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, PPARA, PPARG, PRKCG, RORC, SRC, TOP2A |
6.31697 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
6.30524 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, F2, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
6.29489 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.29015 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, ESR1, F2, F3, FLT3, HSP90AB1, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.2845 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FLT3, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIM1, PPARA, PPARG, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
6.28362 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.2496 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, PPARG, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.21498 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, F2, FABP4, HSP90AB1, HSPA1A, MMP12, MMP2, PPARA, PPARG, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.19954 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.18487 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AXL, BCL2, CA1, CA2, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, RORC, SMAD3, SRC, TEK, TRPV1 |
6.11997 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
6.03031 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
6.00071 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.99536 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, HSP90AB1, NQO2, PTGS1, RORC |
5.92914 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSP90AB1, INSR, PRKCA, PRKCE, SRC |
5.9227 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
5.88756 |
|
[BP] GO:0051937 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
5.87486 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.87486 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
5.86997 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.82583 |
|
[BP] GO:0006811 |
None
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM5, DRD1, DRD2, DRD3, FABP3, PPARA, PPARG, PRKCB, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
5.82583 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.81665 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F2, F3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, INSR, MET, MMP9, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, XDH |
5.73382 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
5.73382 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TYR, XDH |
5.73049 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.70012 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DRD1, EGFR, ESR1, FLT3, IGF1R, INSR, MMP2, NR3C1, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
5.69845 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
5.64431 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, F2, MMP12, PPARA, PPARG, PRKCD, SMAD3, TEK |
5.56315 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CYP19A1, DRD1, DRD2, DRD3, F2, PPARA, PPARG, PRKCD, SMAD3, TEK |
5.5049 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, PPARG, RORC, SRC |
5.48819 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PIM1, PPARA, PPARG, RORC, SRC |
5.47657 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, F2, HCAR2, PIK3CB, PTGS2 |
5.46456 |
|
[BP] GO:0032787 |
None
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PPARA, PPARG, PTGS1, PTGS2 |
5.45091 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, ESR1, FABP4, GPR35, IGF1R, MET, MMP9, PIM1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC |
5.44357 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
5.42765 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F2, F3, FLT3, GPR35, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TRPV1 |
5.41865 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, DUSP3, EGFR, FLT3, IGF1R, INSR, KDR, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
5.40382 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, F2, PPARA, SMAD3 |
5.40382 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
5.40382 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, TYR |
5.40382 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, IGF1R, INSR, PPARA, PPARG, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.39244 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.36058 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
5.36058 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.36058 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CHRM1, DRD2, DRD3, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
5.34077 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
5.34077 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.32258 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PPARG, PRKCG, RORC, TOP2A |
5.30717 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD17B1, HSD17B2 |
5.29228 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CHRM1, CHRM3, CHRM5, CYP1A1, EGFR, ESR1, FLT3, MET, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
5.25673 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, F2, FLT3, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
5.20709 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HSP90AA1, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PPARG, PRKCD, PTPN1, SRC, TEK |
5.1942 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F2, F3, FLT3, HSP90AA1, HSP90AB1, HSPA1A, INSR, PIK3CA, PIK3CB, PPARG, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, XDH |
5.1753 |
|
[BP] GO:0015844 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
5.16051 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.16051 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, EGFR, FLT3, INSR, KDR, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
5.13903 |
|
[BP] GO:0009410 |
None
|
DRD1, DRD2, DRD3, EGFR, HSP90AB1, NR3C1, PPARG, PRKCE, PRKCG |
5.11533 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, DRD2, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
5.09886 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
5.08853 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
5.03293 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
5.00562 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
5.00562 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.99657 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, EGFR, HSPA1A |
4.96988 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSP90AA1, HSP90AB1, HSPA1A, INSR, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TOP2A |
4.8584 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, CHRM5, DRD2, DRD3 |
4.8584 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.85424 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, IGF1R, INSR, MMP2, PPARG, PRKCD, PTGS2, SRC, TRPV1 |
4.83433 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, F2, PPARA, PPARG, PRKCD, SMAD3, TEK |
4.8155 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.80019 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PPARG, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TOP2A |
4.78482 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.78047 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX12, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HSD11B1, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGS1, PTGS2 |
4.73775 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, ALOX12, DRD1, DRD2, MET, PIK3CA, TRPV1 |
4.73775 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
4.70422 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, DRD2, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
4.68995 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, PPARG, RORC, SRC |
4.66665 |
|
[BP] GO:1903426 |
None
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
4.65941 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.61352 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CHRM1, DRD2, DRD3, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.60409 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.57373 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.56359 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.55432 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.54332 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP4, FLT3, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.53575 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, DRD2, DUSP3, ESR1, F2, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
4.5331 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.53238 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, HSP90AA1, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TOP2A |
4.53238 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HSP90AA1, HSP90AB1, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
4.53227 |
|
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, ESR1 |
4.50213 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.49879 |
|
[BP] GO:0051234 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, F10, F2, FABP3, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
4.49539 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, IGF1R, INSR, MMP2, PPARG, PRKCD, PTGS2, SRC, TRPV1 |
4.48438 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.46737 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
4.45669 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3, SRC |
4.45579 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.44271 |
|
[BP] GO:0043279 |
None
|
DRD2, DRD3, HSP90AB1, PPARG, PRKCE, PRKCG, TRPV1 |
4.38414 |
|
[BP] GO:0006810 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, F10, F2, FABP3, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
4.36449 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, DRD2, DRD3, EGFR, PRKCE, PTGS2 |
4.36337 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, DRD2, DRD3, EGFR, PRKCE, PTGS2 |
4.36337 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, ESR1, HSPA1A, IGF1R, MET, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
4.36204 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
4.35959 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.35959 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, CHRM3, DRD2, DRD3, EGFR, GPR35, HCAR2, PRKCA, PTGS2, SMAD3, TRPV1 |
4.3497 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, F2, FLT3, HSP90AA1, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.34407 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.33098 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CSNK2A1, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, F2, FABP4, HSP90AB1, HSPA1A, IGF1R, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
4.31436 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, F2, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PPARG, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
4.30888 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2, PRKCE |
4.30213 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PPARG, PRKCD, PRKCE, SMAD3, SRC, TEK |
4.28543 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CHRM1, DRD2, DRD3, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.28543 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, CHRM1, DRD1, DRD2, DRD3, F2, GPR35, MMP9, PRKCD, PRKCE, PTGS2 |
4.2842 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.25784 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, MMP9, PRKCE, PTGS2 |
4.22488 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD17B1, HSD17B2 |
4.22371 |
|
[BP] GO:0042307 |
positive regulation of protein import into nucleus
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3 |
4.20496 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
4.19812 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.19351 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HSP90AB1, HSPA1A, IGF1R, MMP12, MMP9, NR3C1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
4.17668 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA |
4.17271 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, F2, FABP4, PPARA, PPARG, PRKCD, PTGS2, SMAD3, TEK |
4.16785 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGS2 |
4.16247 |
|
[BP] GO:1904591 |
positive regulation of protein import
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3 |
4.15805 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.13831 |
|
[BP] GO:0051179 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, FABP3, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
4.11293 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, F2, FLT3, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.11293 |
|
[BP] GO:0015893 |
None
|
CA2, CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.09241 |
|
[BP] GO:0008217 |
None
|
ADORA1, DRD2, DRD3, PPARA, PPARG, PTGS1, PTGS2, SMAD3 |
4.07169 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A1, SLC22A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
4.06599 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
4.06599 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
4.06599 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
4.06599 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, HSP90AB1, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
4.05423 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, HSP90AB1, MET, MMP9, PPARA, PRKCD, SRC |
4.02652 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
4.02368 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, PTGS1, PTGS2 |
4.02368 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
3.97717 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, ESR1, F2, GPR35, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.96245 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, BCL2, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, F2, HCAR2, HSP90AB1, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.96094 |
|
[BP] GO:0003018 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2, SRC, TEK |
3.9606 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.95897 |
|
[BP] GO:0040008 |
regulation of growth
|
ALOX12, APP, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, F2, HSPA1A, INSR, PIK3CA, PIM1, PPARG, SMAD3 |
3.95144 |
|
[BP] GO:0007188 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3 |
3.94425 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, DRD1, DRD2, DRD3, EGFR, INSR, PRKCG, PTGS2 |
3.93843 |
|
[BP] GO:0038128 |
None
|
EGFR, HSP90AA1, PIK3CA, PRKCA, SRC |
3.92087 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, KDR, PRKCA, PTPN1, SRC, TEK |
3.91373 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, HSP90AA1, HSP90AB1, IGF1R, INSR, PRKCD, PRKCG, SRC |
3.90869 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, HSP90AB1, MET, MMP9, PPARA, PPARG, PRKCD, SMAD3, SRC |
3.89463 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.87779 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, PPARG, RORC |
3.87207 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, INSR, PPARA, PPARG, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.86493 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
CHRM5, FABP3, FLT3, PRKCD, SRC, TEK |
3.85816 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, HSP90AA1, KDR, PIK3CA, PIK3CB, SRC |
3.85816 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.82075 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PPARG, PRKCG, PTPN1, SRC |
3.82075 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
3.8046 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.7561 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ALOX12, APP, AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, HSP90AB1, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, XDH |
3.75108 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, PRKCD, SRC, TEK |
3.72508 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSP90AB1, INSR, PPARG, PTGS2, SRC |
3.7038 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.68469 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.68262 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, TYR |
3.66817 |
|
[BP] GO:0071702 |
None
|
ADORA1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM5, DRD1, DRD2, DRD3, FABP3, HSP90AA1, MMP12, PPARA, PPARG, PRKCB, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
3.65605 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, EGFR, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
3.64622 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.64593 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.64258 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
3.60809 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.60046 |
|
[BP] GO:1901655 |
None
|
AKR1B1, EGFR, NR3C1, PPARG, PRKCE, SRC |
3.58054 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, PPARG, RORC, SMAD3, SRC, TOP2A |
3.57633 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, NR3C1, PPARG, PRKCE, SRC |
3.55941 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PPARG, PTGS2, TYR |
3.55412 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.5504 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.53997 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.53997 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.52956 |
|
[BP] GO:0032409 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, MMP9, PPARG, PRKCD, PRKCE |
3.49929 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSP90AA1, HSP90AB1, HSPA1A, INSR, PRKCE |
3.49512 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, MMP12, PRKCE, SRC, TRPV1 |
3.49147 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3 |
3.48229 |
|
[BP] GO:0038096 |
Fc-gamma receptor signaling pathway involved in phagocytosis
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.48023 |
|
[BP] GO:0002433 |
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.48023 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.47861 |
|
[BP] GO:0051972 |
regulation of telomerase activity
|
AURKB, HSP90AA1, HSP90AB1, PPARG, SRC |
3.47421 |
|
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.46882 |
|
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.46882 |
|
[BP] GO:0002431 |
Fc receptor mediated stimulatory signaling pathway
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.44326 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, HSP90AA1, HSP90AB1, IGF1R, INSR, PIK3CA, PPARG, PRKCD, PRKCG, SRC |
3.43874 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.40867 |
|
[BP] GO:0038094 |
Fc-gamma receptor signaling pathway
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.40469 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD17B2, HSP90AB1, INSR, MMP2, MMP9, PPARG, PTGS2, SRC, TOP2A |
3.40409 |
|
[BP] GO:0060359 |
None
|
DRD1, DRD2, DRD3, HSP90AB1, PRKCE, PRKCG |
3.40289 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.40144 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.37118 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.36686 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.36686 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PPARG, PRKCE, PTGS2, SRC |
3.36543 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, SRC |
3.36543 |
|
[BP] GO:0050994 |
None
|
ADORA1, HCAR2, PPARA, PRKCD, PRKCE |
3.36543 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, EGFR, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, MET, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, XDH |
3.36127 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, CHRM1, CHRM3, CHRM5, DRD2, DRD3, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PRKCD, SLC22A2, TRPV1, XDH |
3.34584 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.34391 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.34391 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, CHRM1, EGFR, F2, HSP90AB1, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.33485 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, HSP90AB1, INSR, KDR, PIM1, PPARG, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK |
3.33173 |
|
[BP] GO:0015696 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.33173 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
3.30175 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, KDR, PRKCA, SRC, TEK |
3.28503 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.28324 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, F3, KDR, PPARG, PRKCA, PRKCB, PTGS2, TEK, XDH |
3.27827 |
|
[BP] GO:0061041 |
regulation of wound healing
|
ALOX12, F2, F3, PRKCA, PRKCD, PRKCE, SMAD3 |
3.24956 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.2433 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.24058 |
|
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.22316 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, APP, CA2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HCAR2, INSR, PIK3CA, PIK3CB, PPARG, SRC |
3.22316 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
3.22125 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PPARG, PTGS2, TEK, TRPV1, TYR |
3.20299 |
|
[BP] GO:0072347 |
None
|
DRD2, DRD3, HSP90AB1, PRKCE, PRKCG |
3.19973 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
3.1955 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, ESR2, PPARG, PRKCG, PTGS2, TEK, TRPV1 |
3.1955 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, PPARG, RORC |
3.18388 |
|
[BP] GO:0003013 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2, SRC, TEK |
3.18388 |
|
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSP90AB1, INSR, PPARG, SRC |
3.18376 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.17249 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
3.17154 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, EGFR, ESR1, FLT3, INSR, NR3C1, PPARG, PRKCD, PRKCE, SRC |
3.16853 |
|
[BP] GO:0035303 |
None
|
ADORA1, CHRM5, DRD2, HSP90AB1, NUAK1, PRKCD, SMAD3 |
3.15643 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, IGF1R, INSR, PPARG, PRKCD, SRC |
3.1441 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE |
3.13888 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, PTGS2 |
3.13862 |
|
[BP] GO:0045088 |
regulation of innate immune response
|
DRD2, ESR1, HSP90AB1, HSPA1A, MMP12, MMP2, PPARG, PRKCD, PRKCE, PTPN1, SRC |
3.12972 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, ESRRB, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
3.12394 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, BCL2, CHRM1, CSNK2A1, DRD1, DRD2, DRD3, EGFR, F2, HSP90AB1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.12377 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, PTGS1, PTGS2 |
3.11768 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.09325 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
3.09325 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.08628 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F2, F3, FABP4, KDR, MET, PRKCA, PTGS2, SMAD3 |
3.08628 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HSP90AB1, HSPA1A, IGF1R, KDR, MMP12, MMP9, NR3C1, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
3.08088 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
3.07697 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
3.07382 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, NR3C1, PTGS2, SRC |
3.06159 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, BCL2, CHRM1, CSNK2A1, EGFR, F2, HSP90AB1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.04985 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
3.02872 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, PTGS2, TYR |
3.02177 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.01333 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, TRPV1 |
3.01333 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, SRC |
3.01309 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, NR3C1, PTGS2, SRC |
3.00567 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK |
2.99792 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR |
2.99076 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, PTGS2 |
2.98874 |
|
[BP] GO:0006855 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
2.98874 |
|
[BP] GO:1900180 |
regulation of protein localization to nucleus
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3, SRC |
2.98197 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGS1, PTGS2 |
2.97755 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, FABP3, FABP4, FUT7, HSP90AA1, HSPA1A, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
2.97001 |
|
[BP] GO:0043278 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.97001 |
|
[BP] GO:0014072 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.97001 |
|
[BP] GO:0010543 |
regulation of platelet activation
|
ALOX12, F2, PRKCA, PRKCD |
2.97001 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, PTGS2 |
2.96426 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.94848 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, KDR, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.94176 |
|
[BP] GO:0090066 |
None
|
ADORA1, ALOX15, CHRM1, CHRM3, DRD1, EGFR, HSP90AB1, PRKCD, PRKCE, PTGS2 |
2.93674 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.92286 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.92286 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.91926 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.91926 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.91926 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.91926 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.91926 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, DRD1, DRD2, DRD3, EGFR, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
2.91926 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA |
2.91926 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.91926 |
|
[BP] GO:0015908 |
None
|
DRD2, DRD3, FABP3, PPARA, PPARG |
2.91926 |
|
[BP] GO:0045765 |
regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, PPARG, PRKCA, PRKCB, PTGS2, TEK |
2.91699 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, PRKCE, SRC |
2.89222 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.89222 |
|
[BP] GO:0035304 |
regulation of protein dephosphorylation
|
ADORA1, DRD2, HSP90AB1, NUAK1, PRKCD |
2.89222 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.88699 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.88699 |
|
[BP] GO:1903034 |
regulation of response to wounding
|
ALOX12, F2, F3, PRKCA, PRKCD, PRKCE, SMAD3 |
2.88388 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, PRKCD, PRKCE, PTPN1, SRC |
2.8808 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
ALOX12, APP, AXL, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK |
2.85696 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCL2, CHRM1, CHRM3, CHRM5, CYP1B1, DRD1, DRD2, DRD3, EGFR, INSR, PIK3CA, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
2.84449 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
2.84449 |
|
[BP] GO:0007611 |
None
|
APP, DRD1, DRD2, DRD3, EGFR, INSR, PRKCG, PTGS2 |
2.83113 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUT7, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PRKCB, PRKCD, PRKCE, RORC, SMAD3, TRPV1 |
2.82778 |
|
[BP] GO:0042306 |
regulation of protein import into nucleus
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3 |
2.82526 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.82526 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
2.82138 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
2.79616 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.78896 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.78896 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.78896 |
|
[BP] GO:1904589 |
regulation of protein import
|
APP, EGFR, F2, HSP90AB1, PRKCD, PTGS2, SMAD3 |
2.78482 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.7546 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.7546 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, RORC, SRC |
2.74619 |
|
[BP] GO:0030258 |
lipid modification
|
ALOX12, CYP1A1, CYP3A4, EGFR, MET, PIK3CA, PIK3CB, PPARG |
2.74381 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.7196 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.7196 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.71336 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.69728 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.69728 |
|
[BP] GO:0097746 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2 |
2.69382 |
|
[BP] GO:0035296 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2 |
2.69382 |
|
[BP] GO:0031100 |
animal organ regeneration
|
AXL, CSNK2A1, EGFR, FLT3, PPARG |
2.69114 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTGS2 |
2.69114 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3 |
2.69114 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.68582 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR |
2.67828 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.66052 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD17B1, HSD17B2 |
2.66052 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD |
2.64087 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PPARG, PTGS2 |
2.62391 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3 |
2.61318 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, DRD2, DRD3, GPR35, HSPA1A, MMP9, PRKCB, PRKCE, PTGS2 |
2.61318 |
|
[BP] GO:0045927 |
positive regulation of growth
|
ALOX12, BCL2, CSNK2A1, DRD2, EGFR, F2, INSR, PIM1 |
2.61318 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MMP12, PRKCE, SRC |
2.61318 |
|
[BP] GO:0050678 |
None
|
EGFR, F3, KDR, MMP12, PPARG, PRKCA, SMAD3, TEK, XDH |
2.60717 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.60283 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ALOX12, APP, AXL, BCL2, DRD2, DRD3, EGFR, F2, GPR35, HSP90AB1, PPARG, PRKCD, PTGS2, SMAD3, TEK, XDH |
2.60278 |
|
[BP] GO:0070542 |
None
|
FABP3, PPARG, PRKCE, PTGS2, SRC |
2.59588 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, PTGS1, PTGS2 |
2.59588 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.59419 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F2, F3, INSR, KDR, PIM1, PPARG, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, XDH |
2.58821 |
|
[BP] GO:0045776 |
None
|
ADORA1, DRD2, DRD3, PPARA |
2.56632 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HSP90AB1, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
2.5661 |
|
[BP] GO:0050880 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2 |
2.56116 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, PPARG, RORC |
2.55256 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, PPARG, PTGS2, TRPV1, TYR |
2.54976 |
|
[BP] GO:0001936 |
None
|
F3, KDR, PPARG, PRKCA, TEK, XDH |
2.54753 |
|
[BP] GO:0035150 |
None
|
ADORA1, CHRM1, CHRM3, DRD1, EGFR, PTGS2 |
2.54753 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.54151 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.54151 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.54151 |
|
[BP] GO:0051131 |
None
|
HSP90AA1, HSP90AB1, HSPA1A |
2.54151 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.53708 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.53708 |
|
[BP] GO:0038127 |
None
|
EGFR, HSP90AA1, PIK3CA, PRKCA, SRC |
2.53529 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.53529 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.53529 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FLT3, FUT7, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TYR, XDH |
2.52201 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, PPARG |
2.52201 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.52201 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.52201 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.52201 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.52201 |
|
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, EGFR, FLT3, PPARG |
2.51382 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, INSR, PTGS2 |
2.51382 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD |
2.50132 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.50132 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.47944 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4 |
2.47744 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, NR3C1, PTGS2 |
2.46647 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, PPARG, PTGS2, SRC, TRPV1, TYR |
2.46331 |
|
[BP] GO:0051248 |
None
|
APP, CSNK2A1, DUSP3, EGFR, F2, FABP4, HSP90AB1, HSPA1A, IGF1R, MMP9, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.44604 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, F2, PIK3CA, PIK3CB, PTGS1, PTGS2, TRPV1 |
2.44074 |
|
[BP] GO:1900046 |
regulation of hemostasis
|
ALOX12, F2, F3, PRKCA, PRKCD |
2.43748 |
|
[BP] GO:0030193 |
regulation of blood coagulation
|
ALOX12, F2, F3, PRKCA, PRKCD |
2.43748 |
|
[BP] GO:0034762 |
None
|
APP, BCL2, CA2, DRD1, DRD2, DRD3, F2, GPR35, MMP9, PRKCE |
2.4113 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.4113 |
|
[BP] GO:0010544 |
negative regulation of platelet activation
|
ALOX12, F2, PRKCD |
2.4113 |
|
[BP] GO:0090330 |
regulation of platelet aggregation
|
ALOX12, PRKCA, PRKCD |
2.4113 |
|
[BP] GO:0010959 |
None
|
ADORA1, BCL2, DRD1, DRD2, DRD3, F2, GPR35, PRKCE, PTGS2 |
2.4113 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, PRKCE |
2.40776 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AXL, EGFR, ESR1, FLT3, NR3C1, PPARG, PRKCE, RORC, SRC |
2.40417 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AXL, BCL2, CBR1, CDC25B, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GLO1, KDR, MET, MMP2, MMP9, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.40132 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, PRKCE, SRC, TRPV1 |
2.3953 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.39372 |
|
[BP] GO:2000146 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, PPARG |
2.38478 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3 |
2.38478 |
|
[BP] GO:0006939 |
None
|
CHRM3, DRD1, DRD2, TRPV1 |
2.38478 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, HSPA1A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.37457 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.36585 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, HSPA1A, MMP9, NUAK1, PPARG, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TOP2A, TRPV1 |
2.35739 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.35503 |
|
[BP] GO:0035306 |
None
|
ADORA1, HSP90AB1, PRKCD, SMAD3 |
2.35503 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.35338 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.35338 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, F2, GPR35, PRKCE, SMAD3, TRPV1 |
2.3424 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, CHRM3, DRD2, EGFR, PTGS2 |
2.3424 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, DRD2, DRD3, EGFR, HCAR2, MMP12, PRKCA, PRKCE, SRC |
2.32884 |
|
[BP] GO:0050818 |
regulation of coagulation
|
ALOX12, F2, F3, PRKCA, PRKCD |
2.32593 |
|
[BP] GO:0034766 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.32593 |
|
[BP] GO:1904062 |
None
|
APP, DRD1, DRD2, DRD3, F2, GPR35, MMP9, PRKCE |
2.32491 |
|
[BP] GO:0009266 |
None
|
ADORA1, HSP90AA1, HSPA1A, PPARG, PTGS2, TRPV1 |
2.31513 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3 |
2.29453 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.29453 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.28749 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, PRKCG |
2.2789 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, PRKCG |
2.2789 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
APP, CSNK2A1, DRD2, EGFR, ESR1, F3, HSP90AB1, HSPA1A, MMP9, NUAK1, PPARG, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.2789 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, KDR, TEK |
2.27251 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.27251 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.27251 |
|
[BP] GO:1905323 |
None
|
HSP90AA1, HSP90AB1 |
2.27251 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.27251 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.27251 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.27251 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.27251 |
|
[BP] GO:0051271 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, PPARG |
2.2483 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AURKB, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, MMP12, NR3C1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
2.24665 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3 |
2.24665 |
|
[BP] GO:0015909 |
None
|
DRD2, DRD3, FABP3, PPARG |
2.24665 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.24488 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.24488 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.24488 |
|
[BP] GO:0010594 |
regulation of endothelial cell migration
|
KDR, MET, PPARG, PRKCA, PTGS2, TEK |
2.24119 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, PIK3CA, PTGS2 |
2.24093 |
|
[BP] GO:0002429 |
immune response-activating cell surface receptor signaling pathway
|
BCL2, HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, SRC |
2.23156 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, PRKCG |
2.22615 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, PRKCG |
2.22615 |
|
[BP] GO:0034763 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.22363 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.22263 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.22263 |
|
[BP] GO:0031334 |
positive regulation of protein complex assembly
|
ALOX15, ESR1, HSPA1A, MET, MMP1, PRKCE, SRC |
2.21771 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.21748 |
|
[BP] GO:0051924 |
regulation of calcium ion transport
|
BCL2, DRD1, DRD2, F2, GPR35, PRKCE, PTGS2 |
2.20905 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.20905 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.20905 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.20905 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.20905 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC |
2.19723 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.19548 |
|
[BP] GO:0050996 |
None
|
PPARA, PRKCD, PRKCE |
2.19548 |
|
[BP] GO:0022898 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, MMP9, PRKCE |
2.18998 |
|
[BP] GO:0090257 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, PRKCA, PTGS2, SMAD3 |
2.18998 |
|
[BP] GO:0045785 |
positive regulation of cell adhesion
|
ALOX12, ALOX15, KDR, PIK3CA, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.1852 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, CYP1B1, ESR1, ESR2, HSPA1A, PIM1, PPARG, PRKCB |
2.17751 |
|
[BP] GO:0034097 |
response to cytokine
|
ALOX15, AXL, BCL2, FABP4, FLT3, HSP90AB1, PRKCA, PTGS2, SRC, TRPV1 |
2.1701 |
|
[BP] GO:0002252 |
None
|
ALOX5, APP, BCL2, F2, FUT7, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PIK3CA, PIK3CB, PRKCD, PRKCE, RORC, SRC |
2.1701 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX12, ALOX15, CYP19A1, CYP3A4, TYR |
2.16922 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.16922 |
|
[BP] GO:0001558 |
regulation of cell growth
|
ALOX12, BCL2, CSNK2A1, EGFR, ESR2, F2, HSPA1A, PPARG, SMAD3 |
2.14819 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CSNK2A1, DRD2, DRD3, DUSP3, FABP4, IGF1R, MMP9, PPARG, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
2.14819 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.14506 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.14506 |
|
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.14506 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.14506 |
|
[BP] GO:2000278 |
regulation of DNA biosynthetic process
|
AURKB, HSP90AA1, HSP90AB1, PPARG, SRC |
2.14197 |
|
[BP] GO:0040013 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, PPARG |
2.13839 |
|
[BP] GO:0043254 |
regulation of protein complex assembly
|
ALOX15, ESR1, HSP90AA1, HSPA1A, MET, MMP1, PRKCD, PRKCE, SRC |
2.13616 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, ESRRB, INSR, PPARA, PRKCA |
2.13093 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
2.12829 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.12642 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, KDR, PRKCE, SMAD3, TEK |
2.12642 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, MMP12, PRKCE, SRC |
2.12208 |
|
[BP] GO:0000122 |
None
|
AURKB, DRD3, ESR1, ESR2, ESRRA, HSPA1A, MMP12, NR3C1, PPARA, PPARG, RORC, SMAD3, TRPV1 |
2.12047 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CHRM1, CHRM5, CYP1B1, DRD1, DRD2, DRD3, EGFR, INSR, PRKCG, PTGS2, TRPV1, TYR |
2.11681 |
|
[BP] GO:0051254 |
None
|
APP, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MET, MMP12, NR3C1, PPARA, PPARG, RORC, SMAD3, SRC, TOP2A |
2.11066 |
|
[BP] GO:0001959 |
None
|
AXL, HSP90AB1, HSPA1A, MMP12, PPARG, PTPN1 |
2.1089 |
|
[BP] GO:0052548 |
None
|
APP, CSNK2A1, F3, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
2.10181 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP3A4 |
2.10016 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.10016 |
|
[BP] GO:0035902 |
response to immobilization stress
|
CYP1A1, CYP1A2, PPARG |
2.10016 |
|
[BP] GO:0061900 |
None
|
APP, EGFR, TRPV1 |
2.10016 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.10016 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AXL, BCL2, CA2, DRD2, DRD3, EGFR, ESRRA, ESRRB, F2, HSP90AB1, KDR, PPARA, PPARG, PRKCA, PRKCB, PTGS2, RORC, SMAD3, TRPV1, XDH |
2.09992 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.09992 |
|
[BP] GO:0046541 |
None
|
CHRM1, CHRM3 |
2.09992 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.09992 |
|
[BP] GO:0090325 |
None
|
DRD2, DRD3 |
2.09992 |
|
[BP] GO:0007598 |
None
|
F10, F3 |
2.09992 |
|
[BP] GO:0046618 |
None
|
SLC47A1, SLC47A2 |
2.09992 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.09992 |
|
[BP] GO:0032800 |
receptor biosynthetic process
|
ACHE, PPARG |
2.09992 |
|
[BP] GO:0051122 |
hepoxilin biosynthetic process
|
ALOX12, ALOX15 |
2.09992 |
|
[BP] GO:0051121 |
hepoxilin metabolic process
|
ALOX12, ALOX15 |
2.09992 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.09992 |
|
[BP] GO:0010891 |
None
|
PPARA, PPARG |
2.09992 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, DRD1, F2, PIK3CA, PIK3CB, PPARG, PRKCD, PTGS1, PTGS2, SRC, TRPV1 |
2.08474 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
2.0843 |
|
[BP] GO:0019229 |
None
|
CHRM1, CHRM3, EGFR, PTGS2 |
2.0843 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, ESRRB, INSR, PPARA, PRKCA |
2.07505 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, PPARG, PTGS2, SRC, TRPV1, TYR |
2.07119 |
|
[BP] GO:0046649 |
lymphocyte activation
|
AXL, BCL2, FLT3, FUT7, PRKCB, PRKCD, RORC, SMAD3 |
2.0698 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.06147 |
|
[BP] GO:0034110 |
regulation of homotypic cell-cell adhesion
|
ALOX12, PRKCA, PRKCD |
2.06147 |
|
[BP] GO:0022603 |
regulation of anatomical structure morphogenesis
|
ALOX12, BCL2, CYP1B1, ESR1, F2, F3, KDR, PIM1, PPARG, PRKCA, PRKCB, PTGS2, SRC, TEK, XDH |
2.05565 |
|
[BP] GO:1902905 |
positive regulation of supramolecular fiber organization
|
ALOX15, APP, HSPA1A, MET, PRKCE, SMAD3 |
2.04819 |
|
[BP] GO:0038093 |
Fc receptor signaling pathway
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
2.0477 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, INSR, PPARA, PRKCE, RORC, SRC |
2.03592 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CHRM2, CYP1A1, DRD3, EGFR, F2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP1, MMP12, PRKCD, SMAD3, SRC |
2.03241 |
|
[BP] GO:0051282 |
None
|
DRD1, DRD2, F2, PRKCE, TRPV1 |
2.02488 |
|
[BP] GO:0050679 |
None
|
EGFR, F3, KDR, MMP12, PRKCA, TEK |
2.02488 |
|
[BP] GO:0060759 |
None
|
AXL, HSP90AB1, HSPA1A, MMP12, PPARG, PTPN1 |
2.02488 |
|
[BP] GO:0002768 |
immune response-regulating cell surface receptor signaling pathway
|
BCL2, HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, SRC |
2.02471 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, BCL2, CYP1B1, DRD2, FABP3, HSPA1A, PPARG, PTGS2, SMAD3, XDH |
2.02195 |
|
[BP] GO:0006706 |
steroid catabolic process
|
CYP19A1, CYP1A2, CYP3A4 |
2.02008 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.02008 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.02008 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3 |
2.02008 |
|
[BP] GO:0045685 |
None
|
APP, DRD3, F2, PPARG |
2.01684 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, F2, GPR35, PRKCE, TRPV1 |
2.01466 |
|
[BP] GO:0031647 |
None
|
BCL2, HSP90AA1, HSP90AB1, HSPA1A, PRKCD, SMAD3, SRC |
2.00469 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALPL, APP, AXL, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FLT3, GLO1, GPR35, HCAR2, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1 |
7.99175 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD17B2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1, TYR |
5.88677 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, EGFR, HSP90AA1, HSP90AB1, INSR, MET, PRKCG, PTGS2, SLC22A1, SRC, TEK, TRPV1 |
5.4268 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ALOX15, APP, AXL, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DUSP3, EGFR, F10, F2, F3, FLT3, GPR35, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, PRKCG, PTGS2, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
5.39023 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, CA4, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, F10, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
4.93217 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GPR35, HCAR2, HSD11B1, HSD17B2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, PIK3CA, PIK3CB, PRKCG, PTGS1, PTGS2, PTPN1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TEK, TRPV1, TYR |
4.35959 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, CHRM3, EGFR, HSP90AB1, SLC22A1, TEK |
4.32922 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MMP2, MMP9, NQO2, NR3C1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TOP2A, TRPV1, TYR, XDH |
4.06599 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, FLT3, GPR35, IGF1R, INSR, KDR, MET, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
3.68123 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, HSP90AA1, HSP90AB1, INSR, SRC, TRPV1 |
3.43601 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TYR |
3.37641 |
|
[CC] GO:0098793 |
None
|
ADORA1, APP, CHRM1, CHRM2, CHRM3, DRD2, SLC22A2 |
2.91038 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SLC47A1, SMAD3, SRC, TOP2A, TYR, XDH |
2.80902 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, EGFR, F10, F2, FLT3, HSD11B1, HSD17B2, PTGS1, PTGS2, PTPN1 |
2.76588 |
|
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
2.56316 |
|
[CC] GO:0031982 |
None
|
AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DRD2, DRD3, DUSP3, EGFR, F2, F3, FABP3, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPN1, SLC22A2, SLC47A1, SRC, TYR |
2.55256 |
|
[CC] GO:0070062 |
None
|
AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DUSP3, F2, F3, FABP3, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, SLC22A2, SRC |
2.43748 |
|
[CC] GO:1903561 |
None
|
AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DUSP3, F2, F3, FABP3, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, SLC22A2, SRC |
2.40417 |
|
[CC] GO:0043230 |
None
|
AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DUSP3, F2, F3, FABP3, FABP4, GLO1, HSP90AA1, HSP90AB1, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, SLC22A2, SRC |
2.40334 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, FLT3, HSPA1A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, XDH |
2.36362 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CHRM3, DRD1, DRD2, HSP90AA1, HSP90AB1, INSR, PTGS1, SRC, TRPV1 |
2.34982 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CHRM3, DRD1, DRD2, HSP90AA1, HSP90AB1, INSR, PTGS1, SRC, TRPV1 |
2.34982 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.29453 |
|
[CC] GO:0043226 |
organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CBR1, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SLC47A1, SMAD3, SRC, TOP2A, TYR, XDH |
2.23103 |
|
[CC] GO:0043679 |
None
|
CHRM1, CHRM2, CHRM3, DRD2 |
2.19723 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CHRM1, CHRM2, CHRM3, CHRM5, DRD2, PRKCG, SLC22A2, SRC, TRPV1 |
2.06053 |
|
[CC] GO:0005829 |
cytosol
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, AURKB, BCL2, CA1, CA2, CA3, CA7, CBR1, CDC25B, CSNK2A1, DUSP3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, NQO2, NR3C1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TRPV1, TYR, XDH |
2.02195 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, EGFR, HSD11B1, HSD17B2, PTGS1, PTGS2 |
2.02008 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TYR, XDH |
23.4609 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
18.3252 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
18.3035 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, F10, F2, F3, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SRC, TEK, TOP2A, TYR, XDH |
14.752 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, DRD1, DRD2, DRD3, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
13.3924 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TOP2A, TRPV1, TYR, XDH |
13.3793 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PPARA, PPARG, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3 |
12.8323 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.324 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.3205 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TOP2A, TRPV1, TYR, XDH |
10.7438 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HSD11B1, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
8.82516 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, PPARG, RORC, TEK, TRPV1 |
8.42615 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
8.31647 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, XDH |
7.897 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4 |
7.85615 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, PPARG, PRKCE, RORC, SMAD3, TEK, TRPV1 |
7.62075 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.42004 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, PPARG, RORC, TEK, TRPV1 |
7.33394 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, PPARG, RORC, TEK, TRPV1 |
7.03419 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.90472 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, PPARG, RORC |
6.84504 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.70193 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC |
6.63247 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.57463 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
6.55796 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC |
6.34976 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.34857 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.30879 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.29015 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARG, RORC |
6.05367 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARG, RORC |
6.05367 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.94474 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, TYR |
5.9227 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, HSD17B1, NR3C1, PPARA, PPARG, RORC, TRPV1 |
5.74964 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.73382 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, CHRM3, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
5.73049 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD17B1, NR3C1, RORC |
5.69845 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, AOX1, APP, AURKB, AXL, CSNK2A1, EGFR, F10, F2, F3, FABP3, FABP4, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.67135 |
|
[MF] GO:0030235 |
nitric-oxide synthase regulator activity
|
EGFR, ESR1, HSP90AA1, HSP90AB1 |
5.54155 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TYR |
5.39511 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.21924 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
4.92124 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.902 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.83712 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HSP90AA1, HSP90AB1, HSPA1A, MET, NR3C1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A |
4.83695 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.73135 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.68225 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HSD17B1, NQO2, PTGS1, PTGS2, SRC, XDH |
4.67158 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARG, TEK, TRPV1 |
4.40231 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARG, TEK, TRPV1 |
4.40231 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.35959 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HSD11B1, HSD17B1, HSD17B2, XDH |
4.33084 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.22453 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.22316 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
4.21216 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, HSP90AA1, HSP90AB1, IGF1R, KDR, MET, MMP9, NQO2, PPARG, PTGS2, SLC22A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
4.20548 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
4.19171 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP3A4 |
4.18709 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
3.9606 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3 |
3.93721 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.8713 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.7561 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CSNK2A1, DUSP3, EGFR, F10, F2, F3, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
3.57884 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ADORA1, APP, AURKB, AXL, CSNK2A1, EGFR, F2, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.53417 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.47421 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PPARG, PRKCB, SMAD3, SRC |
3.40289 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.3242 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, HSP90AA1, HSP90AB1, NR3C1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
3.29595 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.28074 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.27924 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.27177 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, HSP90AA1, HSP90AB1, NR3C1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
3.2433 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.22316 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.22316 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.22316 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.22316 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.22316 |
|
[MF] GO:0008227 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD2 |
3.19973 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
3.13862 |
|
[MF] GO:0004629 |
None
|
ADORA1, CHRM1, CHRM3, CHRM5 |
3.06497 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HSP90AB1, HSPA1A, KDR, NR3C1 |
3.02995 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.97755 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.97331 |
|
[MF] GO:0042578 |
None
|
ADORA1, ALPL, APEX1, CA3, CDC25B, CHRM1, CHRM3, CHRM5, DUSP3, PTPN1 |
2.96426 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, MET, PPARA, PPARG, PTPN1, SMAD3 |
2.92746 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CSNK2A1, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
2.91926 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.91926 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.91926 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.91926 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.91926 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.91926 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3 |
2.88699 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.88699 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
2.79426 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3 |
2.78896 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD11B1, HSD17B1, HSD17B2 |
2.78278 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, CHRM3, DRD1, DRD2, DRD3 |
2.76359 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
2.7196 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ACHE, AOX1, BCL2, DRD2, FLT3, HSP90AA1, HSP90AB1, NQO2, PTGS2, SLC22A1, SMAD3, TOP2A, TYR, XDH |
2.55064 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.52201 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.52201 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.52201 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.52201 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.52201 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.52201 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.52201 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.52201 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.52201 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.52201 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.51364 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.47944 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, AOX1, AXL, BCL2, DRD2, EGFR, FLT3, HSP90AA1, HSP90AB1, NQO2, PPARG, PTGS2, SLC22A1, SMAD3, TOP2A, TYR, XDH |
2.45843 |
|
[MF] GO:0051213 |
dioxygenase activity
|
ALOX12, ALOX15, ALOX5, PTGS1, PTGS2 |
2.39888 |
|
[MF] GO:0008081 |
None
|
ADORA1, APEX1, CHRM1, CHRM3, CHRM5 |
2.38029 |
|
[MF] GO:0017171 |
serine hydrolase activity
|
ACHE, F10, F2, F3, MMP1, MMP12, MMP2, MMP9 |
2.35732 |
|
[MF] GO:0035257 |
None
|
ESR1, FLT3, PPARG, PRKCB, SMAD3, SRC |
2.3424 |
|
[MF] GO:0015238 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
2.32593 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3 |
2.29453 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.27251 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.27251 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.27251 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.27251 |
|
[MF] GO:0016788 |
None
|
ACHE, ADORA1, ALPL, APEX1, CA1, CA2, CA3, CDC25B, CHRM1, CHRM3, CHRM5, DUSP3, PTPN1 |
2.25963 |
|
[MF] GO:0015101 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.10016 |
|
[MF] GO:0001047 |
None
|
ESR1, ESR2, ESRRB, MMP12, NR3C1, PPARG |
2.09992 |
|
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.09992 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.09992 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.09992 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, BCL2, ESR1, ESRRB, FLT3, PIM1, PPARA, PPARG, PRKCB, SMAD3, SRC |
2.08474 |
|
[MF] GO:0051427 |
hormone receptor binding
|
ESR1, FLT3, PPARG, PRKCB, SMAD3, SRC |
2.06053 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.01684 |
|
[MF] GO:0004252 |
None
|
F10, F2, F3, MMP1, MMP12, MMP2, MMP9 |
2.01466 |
