| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
ADRB2, AKR1B1, ALPL, APEX1, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, HMGCR, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, RORC, SRC, TEK, TYR |
13.05 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRB2, AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCA, RORC, SMAD3, SRC, TEK, TYR |
13.05 |
|
[BP] GO:0042221 |
response to chemical
|
ADRB2, AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR2A, IGF1R, INSR, KDR, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCA, RORC, SMAD3, SRC, TEK, TOP1, TYR |
12.4107 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR7, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PDE3A, PPARA, PRKCA, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
12.0858 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, MMP12, MMP9, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
11.9349 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, MMP12, MMP9, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
11.9281 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
10.5811 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
10.5588 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, SMAD3, SRC, TEK |
10.3148 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.97591 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.81582 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, OPRM1, PIM1, PRKCA, SMAD3, SRC, TEK, XDH |
9.81582 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRB, F3, FABP4, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR7, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TYR |
9.67583 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FLT3, HSD11B2, OPRK1, OPRM1, PDE3A, RORC, SRC, TEK, TYR |
9.6628 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PRKCA, PTPN1, SRC, TEK, XDH |
9.39084 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PDE3A, PPARA, TBXAS1 |
9.25089 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, MMP12, MMP9, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.2441 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
9.05992 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
8.85704 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, OPRK1, PRKCA |
8.81805 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PDE3A, PIM1, PRKCA, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, XDH |
8.52715 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PDE3A, PIM1, PPARA, PRKCA, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, XDH |
8.4769 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HTR2A, INSR, KDR, MET, MMP2, MMP9, PDE3A, PDE3B, PIM1, PPARA, PRKCA, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
8.35803 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7, PDE3A, SRC, TEK |
8.31067 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TOP2A, TYR |
8.2948 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.28996 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, OPRK1, OPRM1, RORC, SRC, TYR |
8.14239 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, RORC, SMAD3, SRC |
8.10873 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
8.10873 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, ADRB2, AKR1B1, ALPI, ALPL, AOX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
8.06272 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PRKCA, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
8.04471 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, EGFR, FABP3, HMGCR, HSD11B2, HTR2A, KDR, OPRK1, OPRM1, PDE3A, SRC, TOP1 |
8.04471 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB2, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
8.04471 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PDE3A, PIM1, PRKCA, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, XDH |
8.04237 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, OPRK1, PDE3B, PPARA, SRC, TEK |
8.03208 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, EGFR, HMGCR, HSD11B2, HSPA1A, HTR2A, MMP2, OPRD1, OPRK1, OPRM1, PPARA, SMAD3, SRC, TEK, TYR |
8.02911 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ADRB2, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HMGCR, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
8.0141 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRB1, ADRB2, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HMGCR, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
8.0141 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
7.95463 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ADRB2, APEX1, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK |
7.94726 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRB2, AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, MMP2, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, RORC, SMAD3, SRC |
7.90999 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, EGFR, ESR1, HTR7, OPRK1, OPRM1, PPARA, RORC, SRC, TOP1, TOP2A |
7.65353 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, IGF1R, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.65353 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, MMP12, MMP2, MMP9, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.64106 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PRKCA, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
7.63722 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD1, DRD2, EGFR, HCAR2, HMGCR, HTR2A, KDR, OPRK1, SRC, TNKS, TNKS2 |
7.63722 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, HTR2A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PRKCA, TEK |
7.53595 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, PDE10A, PDE3A, PDE3B, PIM1, PPARA, TBXAS1, TYR, XDH |
7.52829 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TYR |
7.49864 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRB1, ADRB2, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, KDR, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
7.414 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ADRB2, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, KDR, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
7.33564 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRB1, ADRB2, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.3005 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
7.22779 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7, PDE3A, SRC, TEK |
7.19548 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, DRD1, DRD2, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, SRC, TEK, TYR |
7.10382 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.05814 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9 |
7.05814 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PDE3A, PIM1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK |
7.02208 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PDE3A, PIM1, PRKCA, PTPN1, SMAD3, SRC, TEK |
6.93893 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRB1, ADRB2, AURKB, BCL2, CDC25B, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.87192 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
6.85051 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRB2, BCL2, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MMP12, MMP9, OPRK1, OPRM1, PDE3B, PTPN1, SMAD3, SRC, XDH |
6.81181 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRB2, BCL2, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MMP12, MMP9, OPRK1, OPRM1, PDE3B, PTPN1, SMAD3, SRC, XDH |
6.78944 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, OPRK1, PRKCA, SMAD3, SRC, TEK |
6.77744 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.72226 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2 |
6.69027 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, DRD1, DRD2, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, SRC, TEK, TYR |
6.59737 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
6.58448 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRB1, ADRB2, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.51591 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIM1, PRKCA, SMAD3, SRC, TEK, TNKS2, XDH |
6.47047 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRB2, DRD2, EGFR, FLT3, HMGCR, HTR2A, INSR, KDR, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
6.38402 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PDE3A, PIM1, PRKCA, PTPN1, SMAD3, SRC, TEK |
6.33055 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRB2, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.27404 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PTPN1, RORC, SMAD3, SRC, TOP2A |
6.27113 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
6.26874 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRB2, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, SRC, TEK, XDH |
6.17633 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, HTR1A, HTR7, OPRD1, OPRK1, OPRM1 |
6.16746 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRB2, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, HMGCR, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
6.04666 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
6.03825 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRB2, DRD2, DUSP3, EGFR, FLT3, HMGCR, HTR2A, IGF1R, INSR, KDR, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
5.97805 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD1, DRD2, HMGCR, KDR, OPRD1, OPRK1, SRC |
5.96236 |
|
[BP] GO:0001659 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, HTR2A |
5.89479 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7 |
5.87142 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7 |
5.87142 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRB1, ADRB2, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP9, NUAK1, OPRD1, OPRM1, PIM1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
5.76473 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TNKS, TOP1 |
5.73277 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
ADRB2, AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, OPRK1, PDE3A, PDE3B, RORC, SRC |
5.68708 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRB2, BCL2, CDC25B, DRD2, EGFR, FLT3, HMGCR, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
5.66362 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7 |
5.65703 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7 |
5.63225 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ADRB2, AXL, BCL2, CA2, CA7, CYP19A1, DRD1, DRD2, EGFR, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, INSR, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PPARA, PRKCA, PTPN1, SMAD3, SRC |
5.63058 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRB2, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
5.62878 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRB2, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DUSP3, ESR1, FABP4, GPR35, HMGCR, IGF1R, MET, MMP9, OPRM1, PIM1, PPARA, PRKCA, PTPN1, SRC, TNKS |
5.58394 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, HTR1A, HTR7, OPRD1, OPRK1, OPRM1 |
5.58394 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PDE3A, PPARA, TBXAS1 |
5.56196 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.55393 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
5.47161 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, MMP9, NUAK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
5.43564 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRB1, ADRB2, AXL, BCL2, CA2, CYP1B1, DRD2, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, HTR2A, KDR, MET, MMP12, MMP9, OPRM1, PDE3A, PIM1, PRKCA, SMAD3, SRC, TEK |
5.43564 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, XDH |
5.43368 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.33321 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, SRC |
5.29934 |
|
[BP] GO:0038003 |
None
|
OPRD1, OPRK1, OPRM1, SIGMAR1 |
5.27595 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, PPARA, SMAD3, SRC, TEK |
5.24011 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, OPRK1, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
5.201 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, HTR2A, INSR, MET, SMAD3, SRC |
5.12536 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, PPARA, SMAD3, SRC, TEK |
5.11864 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRB2, BCL2, CDK6, CYP19A1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PDE3B, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
5.08046 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, OPRK1, PRKCA, SMAD3, SRC, TEK |
5.0379 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRB2, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
5.02649 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
DRD2, DUSP3, EGFR, HMGCR, HTR2A, KDR, OPRM1, PRKCA, PTPN1, SRC, TEK |
5.02374 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, HTR1A, HTR7, OPRD1, OPRK1, OPRM1 |
5.00021 |
|
[BP] GO:1901652 |
response to peptide
|
ADRB2, AKR1B1, APEX1, FABP3, HSD11B2, IGF1R, INSR, OPRK1, PDE3B, PPARA, SRC, TEK |
4.91641 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, ADRB2, AKR1B1, DRD1, DRD2, HTR2A, MET |
4.91641 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRB1, ADRB2, CA2, DRD1, DRD2, ESR1, GPR35, HCAR2, HTR1A, HTR2A, HTR7, INSR, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, SIGMAR1, SRC |
4.91438 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRB2, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
4.91438 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, OPRM1, PDE3A, RORC, SRC |
4.90062 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRB2, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
4.87771 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCA, SENP6, SRC, TEK, TNKS, TOP1, TOP2A |
4.81692 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, PPARA, SMAD3, SRC, TEK |
4.79596 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, EGFR, ESR1, F3, FABP4, HMGCR, KDR, MET, MMP12, OPRM1, PPARA, PRKCA, SMAD3, TEK |
4.79596 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HCAR2, HMGCR, HTR2A, PDE3B, PPARA, RORC, SRC, TEK |
4.76936 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRB1, ADRB2, DRD2, EGFR, GPR35, HCAR2, HTR2A, OPRD1, OPRK1, OPRM1, PRKCA, SMAD3 |
4.76936 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, HMGCR, PDE3A |
4.76305 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
4.73701 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, TBXAS1, TYR, XDH |
4.71429 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, EGFR, OPRM1, PPARA, SMAD3 |
4.67948 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP1, MMP12, MMP2, MMP9, PDE10A, PDE3A, PDE3B, SRC, XDH |
4.6644 |
|
[BP] GO:0007200 |
None
|
DRD1, DRD2, ESR1, HTR2A, OPRD1, OPRK1, OPRM1 |
4.65817 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRB1, ADRB2, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.60654 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRB2, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, INSR, KDR, MET, PDE3B, PPARA, PRKCA, PTPN1, SMAD3 |
4.59822 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
4.58397 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.55898 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.50259 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TNKS, TOP1 |
4.46059 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, SMAD3, SRC, TEK |
4.46059 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRB1, ADRB2, AKR1B1, BCL2, CYP1B1, DRD1, DRD2, EGFR, HMGCR, HSD11B2, HTR1A, HTR2A, HTR7, INSR, OPRD1, OPRK1, OPRM1, PDE3A, SRC, TEK, TYR |
4.44829 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, DRD1, EGFR, IGF1R, INSR, MMP2, OPRM1, PDE3A, PDE3B, SRC |
4.43057 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, ADRB2, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, HTR2A, INSR, KDR, NUAK1, OPRM1, PDE3A, PDE3B, PIM1, PPARA, PRKCA, RORC, SMAD3, SRC, TEK, TNKS2, XDH |
4.41546 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DUSP3, EGFR, HSPA1A, INSR, PDE3A, PIM1, PRKCA, SENP6, SMAD3, SRC, TNKS, TOP2A |
4.39365 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
DRD2, EGFR, HMGCR, HTR2A, KDR, OPRM1, PRKCA, SRC, TEK |
4.37535 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, SRC, TNKS, TNKS2 |
4.35704 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TNKS, TOP2A |
4.35501 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.33276 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.33276 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, OPRK1, PRKCA |
4.31867 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.30672 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, OPRD1, OPRM1, PDE3B, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
4.28774 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIM1, PPARA, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
4.27152 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, GBA2, HMGCR, HTR1A, TYR |
4.24956 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, XDH |
4.23556 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PRKCA, PTPN1, SRC, TEK |
4.22191 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, HTR2A, KDR, SRC |
4.20737 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRB2, BCL2, CDC25B, DRD2, EGFR, FLT3, HMGCR, HTR2A, INSR, KDR, MMP9, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SRC, TEK, XDH |
4.1866 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRB2, AKR1B1, APEX1, DRD1, EGFR, ESR1, FLT3, IGF1R, INSR, MMP2, OPRM1, PDE3A, PDE3B, SMAD3, SRC |
4.1866 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, EGFR, F3, INSR, MET, SRC, TEK, XDH |
4.162 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, PDE3A |
4.1267 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, DRD1, EGFR, IGF1R, INSR, MMP2, OPRM1, PDE3A, PDE3B, SRC |
4.11718 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.10583 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
4.10583 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
4.09569 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, ADRB2, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.08897 |
|
[BP] GO:0007190 |
None
|
ADORA3, ADRB1, ADRB2, DRD1, PRKCA |
4.0884 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, OPRM1, SRC |
4.08668 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PDE3B, PTPN1, SRC, XDH |
4.08183 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, ADRB2, BCL2, CA2, CA7, DRD1, DRD2, GPR35, HTR1A, HTR2A, MMP9, OPRD1, OPRK1, OPRM1 |
4.06136 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, OPRK1, OPRM1, PDE3A, SRC, TOP2A |
4.05553 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRB1, ADRB2, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, HSPA1A, HTR2A, INSR, MET, MMP9, OPRD1, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.00031 |
|
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, HTR1A, HTR2A, HTR7 |
3.98338 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, ADRB2, AKR1B1, AKR1B10, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.97494 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, EGFR, HCAR2, TNKS, TNKS2 |
3.94967 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.90793 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRB2, BACE1, CA2, CA7, DRD1, DRD2, EGFR, HTR2A |
3.85712 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRB2, BACE1, CA2, CA7, DRD1, DRD2, EGFR, HTR2A |
3.85712 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD1, DRD2, ESRRB, HTR2A, INSR, OPRM1, PPARA, PRKCA |
3.84092 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, ADRB2, DRD2, PPARA |
3.84092 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.82288 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRB2, CA2, CA7, DRD1, DRD2, EGFR |
3.8196 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ADRB2, ALPL, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, KDR, MET, MMP2, MMP9, PDE3A, RORC, SMAD3, SRC, TEK, TOP2A |
3.81522 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
3.81005 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, SRC, TEK |
3.79858 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, HTR1A, TYR |
3.78675 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, ADRB2, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, IGF1R, INSR, KDR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.75983 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD1, DRD2, ESRRB, HTR2A, INSR, OPRM1, PPARA, PRKCA |
3.75241 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRB1, ADRB2, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.72429 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, HTR2A, OPRK1 |
3.72291 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.72258 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, HSD11B2, HSPA1A, HTR1A, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.70408 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRB2, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.68952 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.64284 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.63062 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.60495 |
|
[BP] GO:0042698 |
ovulation cycle
|
AXL, EGFR, OPRK1, OPRM1 |
3.56542 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, MMP12, OPRK1, OPRM1, PRKCA, SRC |
3.54925 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.51682 |
|
[BP] GO:0072523 |
None
|
AOX1, PDE10A, PDE3A, PDE3B, XDH |
3.5076 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRB2, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
3.49137 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, FABP3, PPARA |
3.478 |
|
[BP] GO:0032868 |
None
|
FABP3, HSD11B2, INSR, OPRK1, PDE3B, PPARA, SRC |
3.47234 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRB2, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
3.46337 |
|
[BP] GO:0030534 |
None
|
DRD1, DRD2, HTR2A, OPRD1, OPRK1, OPRM1, PPARA |
3.45513 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, HTR2A, IGF1R, INSR, PTPN1, SRC |
3.45465 |
|
[BP] GO:0019933 |
None
|
ADRB1, ADRB2, DRD1, DRD2, OPRM1, PDE3A |
3.44775 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.43247 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ADRB2, ALPI, ALPL, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
3.42768 |
|
[BP] GO:0051098 |
regulation of binding
|
ADRB2, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
3.42768 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ADRB2, AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, HMGCR, HTR2A, INSR, KDR, OPRM1, PDE3A, PIM1, PRKCA, SMAD3, SRC, TEK |
3.4048 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, ADRB2, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, IGF1R, INSR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.38534 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1 |
3.36562 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ADRB2, AURKB, BCL2, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.35205 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRB1, ADRB2, AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, EGFR, HTR2A, IGF1R, INSR, KDR, MET, NUAK1, OPRM1, PDE3A, PRKCA, PTPN1, SRC, TEK |
3.34274 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, EGFR, HSPA1A, INSR, PDE3A, SENP6, TNKS |
3.32347 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.32112 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, OPRK1, PDE3B, PPARA, SRC, TEK |
3.31477 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, EGFR, HSPA1A |
3.30798 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1 |
3.30798 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRB1, ADRB2, DRD2, HSD11B2, PPARA, SMAD3 |
3.30289 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ADRB2, AURKB, AXL, BCL2, DRD2, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.27453 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRB1, ADRB2, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, HSPA1A, HTR2A, INSR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.25926 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, GPR35, HTR2A, INSR, MET, SMAD3 |
3.25926 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, SRC, TEK |
3.25391 |
|
[BP] GO:0019935 |
None
|
ADRB1, ADRB2, DRD1, DRD2, OPRM1, PDE3A |
3.24566 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, MMP12, OPRK1, OPRM1, PRKCA, SRC |
3.24536 |
|
[BP] GO:0007610 |
None
|
BCL2, DRD1, DRD2, EGFR, HMGCR, HTR1A, HTR2A, INSR, OPRD1, OPRK1, OPRM1, PPARA |
3.23216 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.23216 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.23216 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.23216 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.23216 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRB2, BCL2, DRD2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PDE3B, PTPN1, SMAD3, SRC, XDH |
3.23216 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, HTR2A |
3.21968 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, PTPN1, SRC, TEK |
3.20114 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
3.19434 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DRD2, DUSP3, EGFR, INSR, PRKCA, SRC |
3.18364 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, ADRB2, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, EGFR, HCAR2, INSR, MMP12, OPRK1, SMAD3, SRC |
3.18299 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1 |
3.17604 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, ADRB2, MMP1, MMP12, MMP2, MMP9 |
3.13278 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ADRB2, ALPI, ALPL, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIM1, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
3.1319 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, PIM1, SRC, TEK, TYR |
3.12606 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
3.09188 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.08843 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, PRKCA, SRC, TNKS, TOP1 |
3.07241 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, HTR2A |
3.07241 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, ADRB2, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MMP2, MMP9, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.06779 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.06363 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.04295 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRB1, ADRB2, DRD1, DRD2, EGFR, KDR, OPRM1, PDE3A |
3.01277 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
3.00514 |
|
[BP] GO:0042596 |
None
|
ADRB1, BCL2, DRD1, HTR1A |
3.00514 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, ADRB2, BCL2, DRD2, TNKS2 |
2.98422 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA, SMAD3, TEK |
2.9831 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.97832 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PTPN1, SMAD3, SRC, TEK |
2.9641 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, SRC |
2.9641 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.9641 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HTR2A, IGF1R, INSR, PTPN1, SRC |
2.95525 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRB2, AURKB, CDC25B, DRD2, EGFR, FLT3, HTR2A, INSR, PTPN1, SRC, TEK, TNKS |
2.95061 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR |
2.93901 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ADRB2, ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.92312 |
|
[BP] GO:0036211 |
protein modification process
|
ADRB2, ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.92312 |
|
[BP] GO:0051930 |
None
|
ADORA1, OPRD1, OPRK1, OPRM1 |
2.92312 |
|
[BP] GO:0051931 |
None
|
ADORA1, OPRD1, OPRK1, OPRM1 |
2.92312 |
|
[BP] GO:0031644 |
None
|
ADORA1, GPR35, OPRD1, OPRK1, OPRM1 |
2.91624 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRB2, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PRKCA, PTPN1, SMAD3, SRC, TEK, XDH |
2.91053 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, OPRD1 |
2.87839 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
2.87839 |
|
[BP] GO:0031635 |
None
|
OPRK1, OPRM1 |
2.87293 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.87293 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, SRC, TEK |
2.87293 |
|
[BP] GO:0007189 |
None
|
ADRB1, ADRB2, DRD1, DRD2, OPRM1 |
2.87293 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PDE3A, SRC |
2.86935 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRB2, DUSP3, EGFR, FLT3, HMGCR, HTR2A, IGF1R, INSR, PTPN1, SRC |
2.86935 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, HTR1A |
2.85232 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, PRKCA, SMAD3, TEK, XDH |
2.84351 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ADRB2, AURKB, AXL, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, OPRD1, PDE3A, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.84351 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, PPARA, SRC, TEK |
2.83698 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, PRKCA, SRC, TNKS, TOP1 |
2.82671 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, EGFR, HTR1A, INSR, SMAD3 |
2.81461 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, PDE10A, PDE3A, PDE3B, XDH |
2.81078 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, SRC, TEK |
2.80459 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.78864 |
|
[BP] GO:0051952 |
None
|
ADORA1, DRD1, DRD2, HTR2A, OPRK1 |
2.77685 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9 |
2.77685 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PDE3B, PPARA, SMAD3 |
2.72852 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.72775 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, OPRM1, SRC, TYR |
2.71291 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, ESR2, HTR2A, HTR7, OPRD1, OPRK1, OPRM1, TEK |
2.70492 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.69953 |
|
[BP] GO:0006198 |
None
|
PDE10A, PDE3A, PDE3B |
2.69953 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR2A |
2.69953 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.65923 |
|
[BP] GO:0050890 |
None
|
ADORA1, DRD1, DRD2, EGFR, HMGCR, HTR2A, INSR, OPRK1 |
2.63903 |
|
[BP] GO:0043412 |
macromolecule modification
|
ADRB2, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, PTPN1, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.63903 |
|
[BP] GO:0010959 |
None
|
ADORA1, ADRB2, BCL2, DRD1, DRD2, GPR35, HTR2A, OPRD1, OPRK1 |
2.62778 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, EGFR, HTR7, PPARA, RORC, TOP1 |
2.6228 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, FABP3, PPARA |
2.59069 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ADRB2, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, EGFR, ESR1, ESRRA, F3, HMGCR, INSR, KDR, OPRM1, PDE3B, PIM1, PRKCA, SMAD3, SRC, TEK, XDH |
2.57713 |
|
[BP] GO:0006195 |
None
|
PDE10A, PDE3A, PDE3B, XDH |
2.57557 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, EGFR, FLT3, HTR2A, INSR, PTPN1, SRC, TEK |
2.57557 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, HMGCR, PPARA, SMAD3, TEK |
2.57557 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, KDR, MET, OPRM1, PRKCA, SMAD3 |
2.57557 |
|
[BP] GO:0070848 |
response to growth factor
|
EGFR, INSR, KDR, OPRD1, OPRM1, PDE3A, SMAD3, SRC |
2.57557 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HMGCR, MMP12, OPRM1, PRKCA, SRC |
2.57535 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRB1, ADRB2, AXL, BCL2, DRD1, DRD2, ESR2, HTR2A, HTR7, OPRD1, OPRK1, OPRM1, TEK |
2.57535 |
|
[BP] GO:0043393 |
regulation of protein binding
|
ADRB2, AURKB, BCL2, MET, MMP9, PPARA, SRC |
2.57236 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, ADRB2, BCL2, CSNK2A1, DRD2, EGFR, ESR2, HSPA1A, INSR, PIM1, SMAD3, TNKS2 |
2.55836 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, GPR35, HTR2A, MMP9 |
2.55177 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.55057 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALPI, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.55025 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.54673 |
|
[BP] GO:1901653 |
cellular response to peptide
|
ADRB2, AKR1B1, APEX1, IGF1R, INSR, PDE3B, SRC |
2.54114 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR7 |
2.52338 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.51564 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, CDC25B, CYP1A1, DUSP3, INSR, PRKCA |
2.5105 |
|
[BP] GO:2001023 |
None
|
DRD1, DRD2, HTR2A, MET, OPRK1 |
2.49444 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.48138 |
|
[BP] GO:0050801 |
ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, FABP3, GPR35, HTR2A, SMAD3 |
2.47455 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PDE3B, PPARA, PRKCA, SMAD3, SRC, TEK |
2.47455 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.47455 |
|
[BP] GO:0009214 |
None
|
PDE10A, PDE3A, PDE3B |
2.47455 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.47351 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.47351 |
|
[BP] GO:0002025 |
None
|
ADRB1, ADRB2 |
2.47351 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
ADRB2, AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.46775 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
DUSP3, EGFR, HMGCR, IGF1R, OPRK1, PTPN1, XDH |
2.46737 |
|
[BP] GO:0070302 |
regulation of stress-activated protein kinase signaling cascade
|
DUSP3, EGFR, HMGCR, IGF1R, OPRK1, PTPN1, XDH |
2.45676 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, PPARA, TBXAS1 |
2.42956 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, MMP12, OPRK1, SRC |
2.42896 |
|
[BP] GO:0006939 |
None
|
DRD1, DRD2, HTR2A, HTR7 |
2.42527 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, SRC |
2.42426 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DUSP3, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.42169 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.4144 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.4144 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GBA2, GLO1, PPARA, TBXAS1 |
2.40492 |
|
[BP] GO:0007631 |
None
|
DRD1, DRD2, OPRD1, OPRK1, OPRM1 |
2.385 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTPN1, SRC |
2.385 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.36609 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.36609 |
|
[BP] GO:0097755 |
None
|
ADRB1, ADRB2, DRD1, EGFR |
2.36609 |
|
[BP] GO:0051100 |
negative regulation of binding
|
ADRB2, AURKB, CYP2D6, MET, PPARA, TNKS |
2.36609 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, SRC |
2.36609 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1 |
2.36609 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.35321 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.35321 |
|
[BP] GO:0016101 |
None
|
AKR1B10, CYP1A1, CYP1B1, EGFR, PDE3A |
2.3519 |
|
[BP] GO:0030817 |
None
|
ADRB1, DRD1, DRD2, OPRM1, PRKCA |
2.33537 |
|
[BP] GO:0043266 |
None
|
ADORA1, DRD1, DRD2, HTR2A, OPRK1 |
2.33537 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, PPARA, RORC, TOP2A |
2.33537 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, ESR2, HTR2A, HTR7, OPRD1, OPRK1, OPRM1, TEK |
2.33537 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, CA2, DRD2, EGFR, HCAR2, HMGCR, MMP12, OPRM1, PRKCA, PTPN1, SMAD3, SRC |
2.32201 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, ADRB2, APEX1, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, MMP12, OPRD1, OPRM1, PIM1, PPARA, PRKCA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.32102 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.31572 |
|
[BP] GO:0050994 |
None
|
ADORA1, HCAR2, PDE3B, PPARA |
2.31572 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRB2, BCL2, DRD1, GPR35, KDR, OPRD1, OPRM1, SRC |
2.30662 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.30662 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, BCL2, DRD2, GPR35, HMGCR, HSPA1A, HTR2A, MMP9, OPRK1, OPRM1 |
2.30554 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1 |
2.30362 |
|
[BP] GO:0071880 |
None
|
ADRB1, ADRB2, DRD2 |
2.30052 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.2889 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, OPRM1, SRC, TYR |
2.27129 |
|
[BP] GO:0007611 |
None
|
DRD1, DRD2, EGFR, HMGCR, HTR2A, INSR, OPRK1 |
2.26764 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.26764 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.26265 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
ADRB1, BCL2, DRD1, HTR1A |
2.26265 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.26265 |
|
[BP] GO:0010038 |
response to metal ion
|
BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9 |
2.24631 |
|
[BP] GO:0032094 |
None
|
CYP1A1, HSD11B2, OPRM1 |
2.24442 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.24442 |
|
[BP] GO:0032922 |
None
|
DRD2, PPARA, RORC, TOP1 |
2.23512 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR7 |
2.23049 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.23049 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.23049 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.23049 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.21837 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
ADRB2, AURKB, BCL2, HSPA1A, INSR, KDR, MET, MMP9, PDE3A, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.20525 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.20502 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, EGFR, FLT3, HTR2A, INSR, PTPN1, SRC |
2.20126 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, SMAD3, XDH |
2.20045 |
|
[BP] GO:0043949 |
None
|
ADRB1, PDE10A, PDE3B |
2.19861 |
|
[BP] GO:0051194 |
None
|
ESRRB, HTR2A, INSR |
2.19861 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.19861 |
|
[BP] GO:0050995 |
None
|
ADORA1, HCAR2, PDE3B |
2.19861 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.19078 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
EGFR, INSR, KDR, OPRD1, PDE3A, SMAD3, SRC |
2.18007 |
|
[BP] GO:0009314 |
response to radiation
|
AURKB, BCL2, DRD1, DRD2, EGFR, HMGCR, OPRK1, OPRM1, TYR |
2.16528 |
|
[BP] GO:0050708 |
None
|
ACHE, DRD2, EGFR, HCAR2, HMGCR, MMP12, OPRM1, PRKCA, SRC |
2.1508 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.14558 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HTR2A, INSR, PPARA, RORC, SRC |
2.14298 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.14029 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6 |
2.14029 |
|
[BP] GO:0050679 |
None
|
EGFR, F3, KDR, MMP12, PRKCA, TEK |
2.13207 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.11535 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.10207 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR2A, HTR7 |
2.10207 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR2A, HTR7 |
2.10207 |
|
[BP] GO:0071875 |
None
|
ADRB1, ADRB2, DRD2 |
2.10207 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.10207 |
|
[BP] GO:0051172 |
None
|
APEX1, AURKB, CSNK2A1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, OPRM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.09604 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.09604 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MMP12, SRC |
2.09325 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, RORC |
2.08516 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, GPR35, HTR2A, SMAD3 |
2.08121 |
|
[BP] GO:1900544 |
None
|
ADRB1, DRD1, ESRRB, HTR2A, INSR |
2.07165 |
|
[BP] GO:0045981 |
None
|
ADRB1, DRD1, ESRRB, HTR2A, INSR |
2.07165 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, SMAD3, TEK |
2.07165 |
|
[BP] GO:0051704 |
multi-organism process
|
AXL, BCL2, CDK6, CYP1A1, EGFR, HSD11B2, HSPA1A, HTR2A, INSR, KDR, MET, MMP1, MMP12, OPRK1, SMAD3, SRC, TOP1 |
2.0657 |
|
[BP] GO:0034762 |
None
|
ADRB2, BCL2, CA2, DRD1, DRD2, GPR35, MMP9, OPRK1, OPRM1 |
2.06245 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.06245 |
|
[BP] GO:0042311 |
None
|
ADRB1, ADRB2, DRD1 |
2.06245 |
|
[BP] GO:0030814 |
None
|
ADRB1, DRD1, DRD2, OPRM1, PRKCA |
2.06245 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.06245 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.06245 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.06245 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.06245 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.06245 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.06245 |
|
[BP] GO:0009166 |
None
|
PDE10A, PDE3A, PDE3B, XDH |
2.06245 |
|
[BP] GO:0046888 |
None
|
ADORA1, DRD2, HMGCR, OPRK1 |
2.06245 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, MMP12, MMP2, PRKCA, PTPN1, SMAD3, SRC |
2.06047 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, OPRK1, PTPN1, XDH |
2.06047 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, RORC |
2.05384 |
|
[BP] GO:0050795 |
None
|
ADORA1, DRD2, HTR1A, HTR2A |
2.04081 |
|
[BP] GO:0051881 |
regulation of mitochondrial membrane potential
|
BCL2, KDR, OPRD1, SRC |
2.04081 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.04081 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, GBA2, HSPA1A, PDE10A, PDE3A, PDE3B, SRC, XDH |
2.03825 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
ADRB2, CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, PPARA, PTPN1 |
2.03825 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, HTR2A, MMP12, OPRK1, OPRM1, SMAD3, SRC, TYR |
2.03245 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRB2, EGFR, FLT3, HTR2A, INSR, PTPN1, SRC |
2.03189 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, HTR2A, INSR, PTPN1, SRC |
2.03152 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.03152 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.03152 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.03152 |
|
[BP] GO:0030802 |
None
|
ADRB1, DRD1, DRD2, OPRM1, PRKCA |
2.03089 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.02552 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.02508 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.01161 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.00656 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.00116 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, MMP12, OPRK1, SRC |
2.00067 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AXL, CDK6, EGFR, ESR1, FLT3, OPRK1, RORC, SRC |
2.00067 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, BACE1, CA4, DRD1, DRD2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK |
5.17626 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALOX5, ALPI, ALPL, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP2, OPRD1, OPRK1, OPRM1, PDE10A, PDE3B, PIM1, PRKCA, PTPN1, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR |
4.57442 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, BACE1, DRD1, DRD2, FLT3, GPR35, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK |
4.36445 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPI, ALPL, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, DRD2, EGFR, ESR1, F3, FLT3, GBA2, GLO1, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP2, OPRD1, OPRK1, OPRM1, PIM1, PRKCA, PTPN1, SMAD3, SRC, TEK |
4.0884 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, HMGCR, HSPA1A, KDR, OPRM1, PDE3B, PRKCA, PTPN1, SIGMAR1, XDH |
3.84145 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPI, ALPL, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PTPN1, SIGMAR1, SRC, TBXAS1, TEK, TYR |
3.54118 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, INSR, KDR, MMP2, MMP9, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PRKCA, PTPN1, SENP6, SIGMAR1, SMAD3, SRC, TBXAS1, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.25926 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, BACE1, CA2, CA4, CA9, DRD1, DRD2, DUSP3, EGFR, F3, FLT3, GPR35, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, SRC, TEK |
3.22295 |
|
[CC] GO:0045121 |
membrane raft
|
BACE1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, SRC, TEK |
3.17604 |
|
[CC] GO:0098857 |
membrane microdomain
|
BACE1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, SRC, TEK |
3.1566 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, ADRB2, CA2, CA4, CA9, DRD1, DRD2, EGFR, HTR2A, INSR, MET, OPRD1, OPRM1, SIGMAR1, SRC, TEK |
3.11102 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, INSR, OPRD1, OPRM1, SRC |
2.9641 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR2A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRM1, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.90788 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, EGFR, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, SIGMAR1, TBXAS1 |
2.87293 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.87293 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, EGFR, FLT3, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTPN1, SIGMAR1, TBXAS1 |
2.82625 |
|
[CC] GO:0032590 |
None
|
INSR, OPRD1, OPRM1 |
2.69953 |
|
[CC] GO:0032589 |
None
|
ADORA1, INSR, OPRD1, OPRM1 |
2.64604 |
|
[CC] GO:0098589 |
membrane region
|
BACE1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, SRC, TEK |
2.63614 |
|
[CC] GO:0031224 |
None
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPI, ALPL, AXL, BACE1, CA12, CA14, CA4, CA9, DRD1, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, SIGMAR1, TBXAS1, TEK, TYR |
2.47047 |
|
[CC] GO:0016021 |
None
|
ADORA1, ADORA3, ADRB1, ADRB2, ALPI, ALPL, AXL, BACE1, CA12, CA14, CA9, DRD1, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, SIGMAR1, TBXAS1, TEK, TYR |
2.12737 |
|
[CC] GO:0043204 |
None
|
DRD2, OPRK1, OPRM1, PDE10A, TOP1 |
2.07165 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.03152 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, ALPI, AOX1, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
15.0429 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
13.05 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DUSP3, EGFR, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PRKCA, PTPN1, SENP6, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
12.4107 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
11.6568 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PPARA, RORC, SIGMAR1, TEK |
9.47237 |
|
[MF] GO:0008270 |
zinc ion binding
|
ALPI, CA1, CA12, CA2, CA4, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PPARA, PRKCA, PTPN1, RORC, SMAD3, TNKS |
8.81805 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CDK6, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PPARA, RORC, SIGMAR1, TEK |
8.69621 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, ESR1, ESR2, ESRRA, ESRRB, GLO1, HTR1A, HTR2A, HTR7, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TYR, XDH |
8.62271 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PPARA, RORC, SIGMAR1, TEK |
8.34868 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PPARA, RORC, SIGMAR1, SMAD3, TEK |
8.10873 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
7.59113 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, EGFR, FLT3, HSPA1A, HTR2A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PIM1, PPARA, PRKCA, SIGMAR1, SRC, TEK, TOP1, TOP2A |
7.48076 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
7.25846 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.8768 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK |
6.3505 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK |
6.3505 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.12713 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, TBXAS1, TYR, XDH |
5.88855 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TYR, XDH |
5.85771 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.56894 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, GLO1 |
5.56894 |
|
[MF] GO:0004985 |
None
|
OPRD1, OPRK1, OPRM1, SIGMAR1 |
5.27595 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TOP1 |
5.06695 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1, XDH |
5.02649 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
5.00773 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.81692 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.81692 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRB2, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
4.7734 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
4.76936 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRB2, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
4.73701 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.68479 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.64646 |
|
[MF] GO:0008227 |
None
|
ADRB1, ADRB2, DRD2, HTR1A, HTR2A, HTR7 |
4.47645 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1, TYR |
4.42826 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.40331 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TOP1 |
4.15763 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, HTR1A, HTR2A, HTR7 |
3.92953 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, ADRB2, ALPI, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HMGCR, HSPA1A, MET, PDE3B, PPARA, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.87329 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.85712 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TOP1 |
3.72429 |
|
[MF] GO:1901338 |
None
|
ADRB1, ADRB2, DRD1, DRD2 |
3.72291 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
3.71526 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, SRC, TBXAS1 |
3.68419 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B2, HSD17B1, SRC, TBXAS1, XDH |
3.65165 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
3.54111 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, ADRB1, ADRB2, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PDE10A, PDE3A, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TOP2A, XDH |
3.50585 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, SRC, TBXAS1 |
3.48969 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.25018 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
3.24586 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
3.24536 |
|
[MF] GO:0042578 |
None
|
ADORA1, ALPI, ALPL, APEX1, CDC25B, DUSP3, PDE10A, PDE3A, PDE3B, PTPN1 |
3.2246 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TBXAS1, TYR |
3.21976 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.21968 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.1566 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRB1, ADRB2, DRD1, DRD2, GPR35, HCAR2, HTR1A, HTR2A, HTR7, OPRD1, OPRK1, OPRM1, SIGMAR1 |
3.08843 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.08579 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, HTR1A, HTR2A, HTR7, OPRM1 |
3.07458 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR2A, HTR7 |
2.97238 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR2A, HTR7 |
2.97238 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TOP1 |
2.9641 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.95875 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.92312 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.87293 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.87293 |
|
[MF] GO:0004119 |
None
|
PDE3A, PDE3B |
2.87293 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PRKCA, PTPN1, SENP6, SRC, TEK, TOP1 |
2.80596 |
|
[MF] GO:0099528 |
None
|
HTR1A, HTR2A, HTR7, OPRM1 |
2.76469 |
|
[MF] GO:0047555 |
None
|
PDE10A, PDE3A, PDE3B |
2.69953 |
|
[MF] GO:0042277 |
peptide binding
|
ACHE, ADRB2, BACE1, IGF1R, INSR, OPRD1, OPRK1, OPRM1 |
2.68096 |
|
[MF] GO:0004115 |
None
|
PDE10A, PDE3A, PDE3B |
2.61442 |
|
[MF] GO:0016788 |
None
|
ACHE, ADORA1, ALPI, ALPL, APEX1, CA1, CA2, CDC25B, DUSP3, PDE10A, PDE3A, PDE3B, PTPN1 |
2.58641 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR |
2.57535 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.54913 |
|
[MF] GO:0004935 |
None
|
ADRB1, ADRB2, DRD2 |
2.54673 |
|
[MF] GO:0004939 |
None
|
ADRB1, ADRB2 |
2.47351 |
|
[MF] GO:0008081 |
None
|
ADORA1, APEX1, PDE10A, PDE3A, PDE3B |
2.4619 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC |
2.44218 |
|
[MF] GO:0033218 |
amide binding
|
ACHE, ADRB2, BACE1, IGF1R, INSR, OPRD1, OPRK1, OPRM1 |
2.36505 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PDE10A, PDE3A, PIM1, PPARA, PRKCA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TOP2A, XDH |
2.33934 |
|
[MF] GO:0043168 |
anion binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PDE10A, PDE3A, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
2.3339 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR2A, HTR7 |
2.31572 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.23049 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIM1, PPARA, PRKCA, PTPN1, RORC, SENP6, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.21837 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.20744 |
|
[MF] GO:0042923 |
None
|
OPRD1, OPRK1, OPRM1 |
2.19861 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, XDH |
2.17527 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, ADRB2, AOX1, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, HMGCR, IGF1R, KDR, MET, MMP9, SMAD3, TOP2A, TYR, XDH |
2.16602 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, ADRB2, BACE1, INSR |
2.11535 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR2A, HTR7 |
2.10207 |
|
[MF] GO:0004114 |
None
|
PDE10A, PDE3A, PDE3B |
2.10207 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR2A, HTR7 |
2.10207 |
|
[MF] GO:0004112 |
None
|
PDE10A, PDE3A, PDE3B |
2.06245 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.06245 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.06245 |
|
[MF] GO:0051380 |
None
|
ADRB1, ADRB2 |
2.06245 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.06245 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PTPN1 |
2.04001 |
