| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CHRM1, CHRM3, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KCNH2, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
24.0398 |
|
[BP] GO:0007187 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, CNR2, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
20.3859 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, ADRA1A, ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KCNH2, KDR, KIT, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PRKCD, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
17.9226 |
|
[BP] GO:0007188 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
17.887 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA3, CA9, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, GPER1, GRIK5, GRM5, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PRKCD, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TYR |
16.7291 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, PPARA, PRKCD, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
16.2542 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CHRNA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
15.8376 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CHRNA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
15.7827 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CHRNA7, CYP1B1, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
15.7299 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1B1, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2 |
15.5796 |
|
[BP] GO:0003018 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
15.331 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CACNA1C, CHRM1, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRB, F10, F2, F3, FABP4, GPER1, GRM1, GRM5, GRM8, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, KCNH2, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TYR |
15.0895 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRM5, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
15.024 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
14.9875 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.9712 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.9712 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRM5, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
14.966 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, ADRB2, AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, FABP3, FLT3, GPER1, GRM5, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MMP2, NR3C1, PPARA, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TEK |
14.9194 |
|
[BP] GO:0097746 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
14.4633 |
|
[BP] GO:0035296 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
14.4633 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
14.367 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESRRB, F2, FABP3, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
14.2169 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESRRB, F2, FABP3, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
14.2169 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
14.1463 |
|
[BP] GO:0050880 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
14.0715 |
|
[BP] GO:0023052 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, KCNH2, PGR, SLC1A1, TEK |
14.043 |
|
[BP] GO:0035150 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
14.0359 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA3, ADRA1A, ADRA1D, AKR1B1, APP, AR, BCL2, CDC25B, CHRM1, CHRNA7, CSNK2A1, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, F2, F3, FABP3, FLT3, GPER1, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PTAFR, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
13.9359 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, HTR1B, HTR5A, INSR, KIT, NR3C1, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK |
13.8042 |
|
[BP] GO:0007193 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
13.4992 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
13.4992 |
|
[BP] GO:0007267 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, SLC1A1, TEK |
13.4649 |
|
[BP] GO:0003013 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
13.3679 |
|
[BP] GO:0007154 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, AXL, BCL2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PTGS2, SLC1A1, TEK |
13.2172 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
13.0007 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CHRM3, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
12.8885 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CHRNA7, CNR1, CSNK2A1, CYP1B1, EGFR, ERBB2, ESRRA, F10, F2, F3, FABP4, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
12.8619 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADRA1A, ADRB2, APP, CA2, CA7, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PTGS2 |
12.5597 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADRA1A, ADRB2, APP, CA2, CA7, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PTGS2 |
12.5597 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRB1, ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CHRM2, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KCNH2, KDR, KIT, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TYR |
12.5254 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESRRB, F2, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
12.4773 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, F2, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
12.2075 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, APP, CA2, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, CNR2, ESR1, F2, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, PTAFR, SRC |
12.205 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.8461 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CHRNA3, CHRNA7, CNR1, CNR2, CYP1A1, CYP1B1, EGFR, FABP3, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KCNH2, KDR, NR3C1, PRKCD, PTAFR, PTGS2, SRC |
11.7534 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
11.5691 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
11.5691 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, CNR1, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3, SRC |
11.4868 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, CNR1, EGFR, ESR1, F2, FABP3, FABP4, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3 |
11.4447 |
|
[BP] GO:0006940 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB2, CHRM1, CHRM2, CHRM3, CHRNA3, GPER1, KIT, PTAFR, PTGS2 |
11.4341 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
ADRA1D, AKR1B1, AR, BCL2, CDC25B, CHRM1, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PTAFR, PTGS2, TEK |
11.4043 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.1546 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, HSD17B2, HTR1B, HTR5A, NR3C1, PTAFR, PTGES, PTGS2, RORC, SRC, TYR |
11.152 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FLT3, GPER1, HSD11B2, HTR1B, HTR5A, NR3C1, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TYR |
11.0831 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, CHRNA7, EGFR, ERBB2, FLT3, GPER1, GRM1, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
10.9956 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA3, ADRB2, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CHRM1, CHRNA3, CNR1, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F2, F3, GPER1, GPR35, GRIK5, GRM5, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK |
10.9874 |
|
[BP] GO:0097756 |
None
|
ADRA1A, ADRA1B, ADRA1D, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
10.799 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
10.7619 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
10.7619 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, FUT7, GLO1, HSD17B3, HSPA1A, HTR2B, HTR2C, MIF, PIK3CA, PIM1, PPARA, PTAFR, PTGES, PTGS1, PTGS2, TYR, XDH |
10.5088 |
|
[BP] GO:0042310 |
None
|
ADRA1A, ADRA1B, ADRA1D, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
10.4199 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, CHRNA7, DUSP3, EGFR, ERBB2, FLT3, GPER1, GRM1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC, TEK, XDH |
10.4098 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
10.4098 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP4, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
10.2478 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, ESR1, FABP3, FABP4, FUT7, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2 |
10.1676 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.0175 |
|
[BP] GO:0044057 |
None
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, EGFR, GPER1, GPR35, GRM1, HTR2A, HTR2C, KCNH2, KIT, PTAFR, PTGS2, SLC1A1, SMAD3 |
10.0008 |
|
[BP] GO:0007200 |
None
|
ADRA1A, ADRA1B, ADRA1D, CHRM1, CHRM2, CHRM3, CHRM5, ESR1, GRM5, HTR2A, HTR2B, HTR2C |
9.97777 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
9.97777 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.97777 |
|
[BP] GO:0003008 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, APP, BCL2, CHRM1, CHRM3, CHRM5, CHRNA7, CNR1, CNR2, CYP1B1, EGFR, GPER1, GRM1, GRM5, GRM8, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KCNH2, KIT, PIK3CA, PTAFR, PTGS2, SRC, TEK, TYR |
9.91774 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
9.77732 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KCNH2, KDR, KIT, MMP2, MMP9, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
9.74595 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, ADRA1B, ADRA1D, AR, AURKB, BCL2, CHRM1, CHRM3, CHRM5, CYP1A1, EGFR, ERBB2, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
9.65932 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, CHRNA7, CNR1, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, F3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KCNH2, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCD, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS2, XDH |
9.65872 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.63886 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA3, ADRA1A, ADRB1, ADRB2, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
9.53793 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, F2, FLT3, GPER1, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
9.46683 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, EGFR, ESR1, F2, FABP3, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
9.46683 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
9.44915 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
9.40029 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
9.40029 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
9.13866 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
9.09624 |
|
[BP] GO:0090066 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALOX15, CHRM1, CHRM3, EGFR, GPER1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PRKCD, PTAFR, PTGS2 |
9.08236 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
9.04416 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADRA1A, ADRB1, ADRB2, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESR1, ESR2, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
9.04143 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, EGFR, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
9.03145 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, F10, F2, F3, FABP4, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
8.90092 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B2, HSD17B3, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
8.89888 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADRB2, ALOX15, APP, AXL, BCL2, CA2, CA7, CACNA1C, CHRM1, CHRNA3, CNR1, CYP19A1, EGFR, ERBB2, F2, GPER1, GPR35, GRIK5, GRM5, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC |
8.86091 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
8.82925 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADRB2, APP, BCL2, CA2, CA7, CACNA1C, CHRM1, CHRNA3, CNR1, F2, GPER1, GPR35, GRM5, HTR1A, HTR1B, HTR2A, KCNH2, MIF, MMP9, PRKCD, PTAFR, PTGS2 |
8.6864 |
|
[BP] GO:0010941 |
regulation of cell death
|
AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CHRNA7, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
8.56214 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EGFR, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
8.41094 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADRA1A, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
8.31733 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PTGS2, SRC, TEK |
8.27681 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
8.24752 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, CHRNA7, DUSP3, EGFR, ERBB2, GPER1, HTR2A, HTR2B, HTR2C, KDR, MIF, PTPN1, SRC, TEK |
8.20648 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, EGFR, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
8.20584 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
8.20552 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
CHRM5, FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
8.17153 |
|
[BP] GO:0045987 |
None
|
ADRA1A, ADRA1B, ADRA1D, CHRM3, GPER1, KIT, PTAFR, PTGS2 |
8.14071 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
8.10798 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, APP, AR, AXL, BCL2, CA2, CHRM3, CHRNA7, CNR1, CYP1B1, EGFR, ESRRB, F2, F3, GPER1, HSPA1A, HTR2A, HTR2B, KDR, KIT, MET, MIF, MMP12, MMP9, PIM1, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK |
8.10795 |
|
[BP] GO:0006937 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, GPER1, KIT, PTAFR, PTGS2 |
8.09422 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA3, ADRA1A, ADRB1, ADRB2, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, F2, F3, FABP4, FLT3, GPER1, GPR35, GRM1, GRM3, GRM5, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
8.02595 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
8.02595 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.97278 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, EGFR, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
7.96768 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADRA1A, ADRA1B, ADRB1, ADRB2, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, GRM1, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.96046 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADRB2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, F2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
7.92956 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
7.86039 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.7708 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, F3, GPER1, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.7355 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADRB2, AURKB, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, F2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
7.73539 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.69012 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK, TYR |
7.68812 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.68023 |
|
[BP] GO:0042391 |
None
|
ADRA1A, ADRB2, APP, BCL2, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KCNH2, KDR, SRC |
7.66311 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, CHRNA7, CNR1, CNR2, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK, TYR |
7.62294 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
CNR1, EGFR, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PTGS2 |
7.62294 |
|
[BP] GO:0019229 |
None
|
ADRA1A, ADRA1B, ADRA1D, CHRM1, CHRM3, EGFR, HTR2A, PTAFR, PTGS2 |
7.55746 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, KIT, MMP9, PRKCD, PTGES, PTGS2, SRC |
7.5392 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.50293 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
CHRM5, CNR1, CYP1A1, F2, FABP3, FLT3, GPER1, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PTGS2, RORC, SRC, TEK |
7.42314 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADRB2, APP, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GRM1, GRM5, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
7.4137 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.39541 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
AURKB, BCL2, CA2, CA7, CACNA1C, CNR1, EGFR, F2, GPER1, HTR2A, HTR2B, HTR2C, KDR, MIF, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
7.35592 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APEX1, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
7.35592 |
|
[BP] GO:0090257 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, GPER1, KIT, PTAFR, PTGS2, SMAD3 |
7.34052 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA3, ADRA1A, ADRB2, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KCNH2, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCD, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.34052 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
7.30929 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.27153 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, ADRA1A, ADRA1B, ADRA1D, APP, BCL2, CACNA1C, CHRNA7, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
7.22329 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
7.22204 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADRB2, APP, AURKB, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GRM1, GRM5, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
7.22204 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRB2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KCNH2, KDR, KIT, MIF, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A |
7.14867 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
7.14867 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, CHRNA7, EGFR, GPER1, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TEK |
7.10799 |
|
[BP] GO:1903522 |
None
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, CACNA1C, CHRM1, CHRM2, CHRM3, EGFR, HTR2A, KCNH2, PTAFR, PTGS2, SLC1A1 |
7.08222 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
7.07678 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRB2, AKR1B1, APEX1, APP, AR, EGFR, ERBB2, ESR1, FLT3, GPER1, GRM5, HTR1B, IGF1R, INSR, KIT, MMP2, NR3C1, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
7.05419 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA3, APEX1, APP, BCL2, CHRM1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F3, GPER1, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.03169 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
7.01828 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
ADRB2, AKR1B1, APEX1, APP, AR, AXL, CYP1B1, EGFR, ESR1, GPER1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SRC |
7.01488 |
|
[BP] GO:1903524 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, EGFR, HTR2A, PTAFR, PTGS2, SLC1A1 |
7.01249 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA3, ADRA1A, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KCNH2, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PRKCD, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.01249 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
CHRNA7, DUSP3, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
6.97794 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, AKR1B1, CACNA1C, CHRNA3, CNR1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, GPER1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HTR1A, HTR2A, HTR2C |
6.91396 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.88654 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
6.87865 |
|
[BP] GO:0045933 |
None
|
ADRA1A, ADRA1B, ADRA1D, CHRM3, GPER1, KIT, PTAFR, PTGS2 |
6.85577 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADRB2, CDC25B, CHRNA3, CHRNA7, EGFR, ERBB2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
6.85254 |
|
[BP] GO:1901652 |
response to peptide
|
ADRB2, AKR1B1, APEX1, APP, CHRNA7, FABP3, GPER1, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK |
6.82932 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
6.72818 |
|
[BP] GO:0045907 |
None
|
ADRA1A, ADRA1B, ADRA1D, EGFR, HTR2A, PTAFR, PTGS2 |
6.72818 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.71115 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
6.67754 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADRB2, APP, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
6.66408 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
6.64936 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, GPER1, HSD11B2, HTR1B, NR3C1, PTAFR, PTGS2, SRC |
6.60286 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.58182 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5, PTAFR |
6.52618 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.50022 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
6.46509 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, EGFR, ERBB2, GPER1, GRM5, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SRC, TEK |
6.44883 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, ADRA1D, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
6.41801 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.40082 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, FABP3, FABP4, FUT7, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2 |
6.39361 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA3, APEX1, APP, BCL2, CACNA1C, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.36138 |
|
[BP] GO:0008217 |
None
|
ADRA1A, ADRB1, ADRB2, AR, CNR1, HSD11B2, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
6.35924 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.34773 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.33195 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.25991 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA3, ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRM5, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.2546 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, ADRA1B, ADRA1D, CACNA1C, ESR1, F2, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, SMAD3 |
6.20606 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA3, ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.1942 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GPER1, HSD11B2, HTR1B, NR3C1, PTAFR, PTGS2, SRC |
6.19404 |
|
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7 |
6.18892 |
|
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7 |
6.18892 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
6.17269 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.16651 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADRB1, ADRB2, AKR1B1, APP, AURKB, BCL2, CA2, CHRNA7, CYP1A1, EGFR, GRM1, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, PPARA, PTAFR, PTGS2, SMAD3, SRC, TEK, TYR |
6.08018 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.07713 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
6.06792 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA3, ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRM5, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.06788 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.06064 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CHRNA7, CNR1, CNR2, CYP1A1, CYP1B1, HTR1B, HTR1D, KDR, PRKCD, SRC |
6.03638 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA3, ADRB2, APP, AXL, BCL2, CA1, CSNK2A1, EGFR, ERBB2, F2, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
6.02828 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGES, PTGS1, PTGS2 |
6.02828 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, GPER1, NR3C1, PTAFR, PTGS2, RORC, SRC |
5.97695 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADRA1A, ADRA1B, ADRA1D, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, FLT3, HSD11B1, HSD17B2, HSD17B3, HTR5A, INSR, KDR, KIT, MMP9, PGR, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
5.92814 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.8939 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, ADRB2, APP, AR, AURKB, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
5.86931 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.82177 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.81629 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, NQO2, PTGS1, PTGS2, TYR, XDH |
5.71591 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
CHRNA7, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
5.71191 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.67875 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
5.6339 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
5.58214 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
5.56452 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.52817 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADRB2, CHRNA7, DUSP3, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
5.49763 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.45195 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
5.42505 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA3, ADRA1A, ADRA1B, ADRB1, ADRB2, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRNA3, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.41027 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
5.4007 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HTR1B, KCNH2, KDR, NR3C1, PRKCD, PTAFR, PTGS2, SRC |
5.39631 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, SRC, TEK, TNKS |
5.38595 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CACNA1C, EGFR, GPER1, GRM5, HTR2B, HTR5A, KDR |
5.35675 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, EGFR, GPER1, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC |
5.33926 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7, CNR1, CNR2, HTR1B |
5.3226 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.29608 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.29608 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.27555 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADRA1A, ADRB2, AR, BCL2, CNR2, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, GPR35, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
5.2453 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADRA1A, ADRB2, AR, BCL2, CNR2, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, GPR35, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
5.21939 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADRB2, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, EGFR, ERBB2, F2, GPER1, HTR2B, INSR, KCNH2, MIF, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
5.18205 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA3, ADRB1, ADRB2, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CHRNA7, CNR2, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, F2, GPER1, HSD11B2, HSPA1A, HTR1A, HTR2C, KIT, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A |
5.17902 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADRB2, CHRNA7, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
5.16451 |
|
[BP] GO:0006811 |
None
|
ABCB1, ADRA1A, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM5, CHRNA3, CHRNA7, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, HTR2C, KCNH2, PPARA, SLC1A1 |
5.12824 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, ADRA1B, ADRA1D, CACNA1C, ESR1, F2, GPER1, GPR35, GRM1, HTR2A, HTR2B, HTR2C |
5.12459 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CHRNA3, CHRNA7, CNR1, EGFR, GRM1, GRM5, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KIT, PPARA, PTGS2 |
5.0924 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADRA1A, ADRB2, ALOX15, AR, BCL2, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ERBB2, ESR1, ESR2, F2, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.08839 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADRA1A, ADRB2, APP, CA2, CA7, CHRNA7, EGFR, GPER1, PTGS2 |
5.07024 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
5.07024 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, SLC1A1 |
5.04909 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
5.03849 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, ADRB2, APP, AR, AURKB, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
5.01245 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
BCL2, CA2, CA7, CACNA1C, F2, GPER1, HTR2A, HTR2B, HTR2C, KDR, SRC |
4.9816 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
4.96058 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, MIF, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
4.96035 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.94681 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
4.94681 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADRA1A, ADRA1B, ADRB2, ALOX15, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.93283 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, EGFR, GPER1, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC |
4.93283 |
|
[BP] GO:0071880 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
4.91389 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CHRNA7, CNR1, CNR2, CSNK2A1, CYP2D6, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
4.9087 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.9087 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.84213 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
4.81626 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.80805 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.80224 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.80224 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, ERBB2, F2, PPARA, SMAD3 |
4.65706 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, EGFR, F2, GPER1, PIK3CB, PTGS2, TNKS, TNKS2 |
4.6548 |
|
[BP] GO:0045913 |
None
|
ESRRB, GPER1, HTR2A, INSR, PPARA, PTAFR, SRC |
4.64775 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, HTR7, KIT, PGR, PPARA, RORC, SRC, TOP2A |
4.54215 |
|
[BP] GO:0071875 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
4.51163 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TNKS |
4.44975 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2, HSD17B3 |
4.39358 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.39358 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRB2, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DUSP3, ESR1, FABP4, GPR35, GRM3, IGF1R, MET, MMP9, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SRC, TNKS |
4.36003 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PPARA, PTGES, PTGS1, PTGS2 |
4.3511 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ADRB2, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, ESR1, GPER1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PRKCD, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.33223 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HTR1B, MMP2, MMP9, PTAFR, PTGS2 |
4.32967 |
|
[BP] GO:0006939 |
None
|
ADRA1A, CHRM3, HTR1D, HTR2A, HTR2B, HTR7 |
4.31673 |
|
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3 |
4.25742 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, PGR, SRC |
4.25742 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CHRNA7, CNR1, CSNK2A1, CYP2D6, DUSP3, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
4.2393 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, PTGS1, RORC |
4.22967 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, APP, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, F2, F3, FABP4, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.20984 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
CNR2, CYP19A1, F2, GPER1, PPARA, PRKCD, SMAD3, TEK |
4.20332 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CHRNA3, CYP1B1, EGFR, GPER1, GRIK5, HTR1A, INSR, PTGS2, SLC1A1, SMAD3 |
4.16624 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.14958 |
|
[BP] GO:0001994 |
None
|
ADRA1A, ADRA1B, ADRA1D |
4.14495 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.14495 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA3, ALOX15, AXL, CNR2, F2, GPER1, KIT, MIF, PIK3CA, PIK3CB, PTAFR, PTGES, PTGS1, PTGS2 |
4.12845 |
|
[BP] GO:0010676 |
None
|
ESRRB, GPER1, INSR, PPARA, PTAFR, SRC |
4.12423 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, CA2, CA7, GRM5, MIF, PRKCD, PTAFR |
4.12415 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADRB2, CHRNA3, CHRNA7, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.11803 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
4.1145 |
|
[BP] GO:0001516 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.10963 |
|
[BP] GO:0046457 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.10963 |
|
[BP] GO:1901653 |
cellular response to peptide
|
ADRB2, AKR1B1, APEX1, APP, GPER1, GRM5, IGF1R, INSR, PRKCD, SRC |
4.10607 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, KIT, MMP9, PTGES, PTGS2 |
4.055 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.04744 |
|
[BP] GO:1904645 |
response to amyloid-beta
|
ADRB2, APP, CHRNA7, GRM5, IGF1R |
4.04744 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.03268 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, EGFR, ERBB2, F2, GPER1, HTR2B, MIF, MMP12, PRKCD, PTGS2, SMAD3, SRC |
3.99835 |
|
[BP] GO:0090087 |
None
|
ACHE, APP, CA2, CACNA1C, CHRM1, CNR1, EGFR, ERBB2, F2, GPER1, HTR2B, HTR2C, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
3.97999 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DUSP3, ESR1, GPER1, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
3.97999 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
3.9791 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, GPER1, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.95233 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, INSR, PRKCD, PTGS2, SMAD3, XDH |
3.94587 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
CNR2, CYP19A1, F2, GPER1, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.90477 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, HTR1B, MMP2, MMP9, PTAFR, PTGS2 |
3.88685 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, ADRB2, APP, AR, AURKB, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.88215 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, INSR, PRKCD, PTGS2, SMAD3, XDH |
3.87764 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSD17B3, INSR, KIT, PGR, PTGS2, SRC |
3.87181 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
3.86431 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, KIT, SRC, TEK |
3.85295 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
3.85295 |
|
[BP] GO:0019933 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, GPER1, HTR5A |
3.85225 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.82102 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, HSD17B3, INSR, KIT, MMP2, MMP9, PGR, PTAFR, PTGS2, SRC, TOP2A |
3.80643 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, GPER1, GRIK5, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PTAFR, SRC |
3.80249 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.79423 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, ADRB2, APP, AR, AXL, BCL2, CA2, CHRNA3, CHRNA7, CNR1, CYP1B1, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, F3, GPER1, HTR2A, HTR2C, INSR, KDR, KIT, MIF, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, XDH |
3.79211 |
|
[BP] GO:0051098 |
regulation of binding
|
ADRB2, APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TNKS |
3.76278 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.75061 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.75061 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.73908 |
|
[BP] GO:0050730 |
None
|
APP, EGFR, FLT3, GRM5, HTR2A, KIT, MIF, PRKCD, PTPN1, SRC |
3.73873 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HTR2A, MIF, PRKCD, PTGS2 |
3.73873 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ADRB2, ALOX15, APP, AR, AURKB, AXL, BCL2, CHRNA3, CHRNA7, CNR1, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, F2, GPER1, GRIK5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PIK3CB, PRKCD, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.73297 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, SLC1A1 |
3.73297 |
|
[BP] GO:0006810 |
None
|
ABCB1, ABCG2, ACHE, ADRA1A, ADRB2, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, CHRNA3, CHRNA7, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNH2, KIT, MIF, MMP12, MMP9, PPARA, PRKCD, PTAFR, SLC1A1, SRC, TNKS, XDH |
3.71866 |
|
[BP] GO:1900542 |
None
|
ADRB1, ESRRB, GPER1, GRM3, GRM8, HTR1B, HTR1E, HTR2A, INSR, PPARA |
3.69327 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, GPER1, KDR, KIT, TEK |
3.68621 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, EGFR, ERBB2, F2, GPER1, HTR2B, MIF, MMP12, PRKCD, PTGS2, SMAD3, SRC |
3.67978 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC, TEK |
3.67978 |
|
[BP] GO:0051234 |
None
|
ABCB1, ABCG2, ACHE, ADRA1A, ADRB2, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, CHRNA3, CHRNA7, EGFR, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNH2, KIT, MIF, MMP12, MMP9, PPARA, PRKCD, PTAFR, SLC1A1, SRC, TNKS, XDH |
3.65548 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTAFR, PTGS2 |
3.65518 |
|
[BP] GO:0050795 |
None
|
CNR1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
3.65248 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
3.65248 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, F3, FABP4, GPER1, KDR, MET, MIF, MMP12, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.63596 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
BCL2, CNR1, GPR35, HTR1B, HTR2A, KCNH2, MMP9, PTGS2 |
3.61445 |
|
[BP] GO:0019935 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, GPER1, HTR5A |
3.61083 |
|
[BP] GO:0031347 |
regulation of defense response
|
CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, GPER1, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
3.60863 |
|
[BP] GO:0006140 |
None
|
ADRB1, ESRRB, GPER1, GRM3, GRM8, HTR1B, HTR1E, HTR2A, INSR, PPARA |
3.59595 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
F2, FLT3, GPER1, KDR, KIT, TEK |
3.58226 |
|
[BP] GO:0032845 |
None
|
BCL2, HTR2A, HTR2B, HTR2C, MIF, SRC, TNKS, TNKS2 |
3.55407 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, ERBB2, F10, F2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK, TNKS, TOP2A |
3.54702 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, ADRB2, APP, BCL2, PIK3CA, TNKS2 |
3.54702 |
|
[BP] GO:0051179 |
None
|
ABCB1, ABCG2, ACHE, ADRA1A, ADRB2, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, CHRNA3, CHRNA7, EGFR, ESR1, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNH2, KIT, MIF, MMP12, MMP9, PPARA, PRKCD, PTAFR, SLC1A1, SRC, TNKS, TNKS2, XDH |
3.51381 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.51241 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA3, ADRA1A, ADRA1B, ADRB2, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRM5, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.46925 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, ADRB2, APP, AR, BCL2, CSNK2A1, EGFR, ERBB2, ESR2, F2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
3.44885 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ALOX15, APP, AXL, BCL2, CA2, CNR1, CNR2, CYP19A1, DUSP3, ERBB2, ESR1, ESRRA, F2, GPER1, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
3.43945 |
|
[BP] GO:0034762 |
None
|
ABCB1, ADRB2, APP, BCL2, CA2, CACNA1C, F2, GPER1, GPR35, GRM5, KCNH2, MMP9, PTAFR |
3.43461 |
|
[BP] GO:0051046 |
None
|
ACHE, CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, GPER1, GRIK5, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PTAFR, SRC |
3.4297 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.41073 |
|
[BP] GO:0051345 |
None
|
ADRA1A, ADRB1, APP, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, KIT, PRKCD, PTAFR, PTPN1, SMAD3, XDH |
3.4019 |
|
[BP] GO:0007189 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, GPER1 |
3.37954 |
|
[BP] GO:0045776 |
None
|
ADRB1, ADRB2, CNR1, PPARA, PTAFR |
3.37874 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, CHRM1, CNR1, EGFR, ERBB2, F2, GPER1, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
3.36052 |
|
[BP] GO:0001666 |
response to hypoxia
|
BCL2, CHRNA7, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
3.34668 |
|
[BP] GO:0043393 |
regulation of protein binding
|
ADRB2, APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC |
3.33624 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.31729 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADRB2, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCD, PTPN1, SMAD3 |
3.31622 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.3142 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.29919 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.28878 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
ADRB2, APP, AR, AURKB, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, GPER1, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PTAFR, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.28878 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, ADRB2, AR, BCL2, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.285 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.27392 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRA1A, ADRB1, APP, CSNK2A1, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, KIT, MMP9, NUAK1, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.2641 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
BCL2, CHRNA7, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
3.2454 |
|
[BP] GO:0060078 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM5 |
3.22896 |
|
[BP] GO:0050678 |
None
|
AR, EGFR, ERBB2, F3, HTR2B, KDR, MMP12, PGR, SMAD3, TEK, XDH |
3.21479 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSD17B3, INSR, KIT, SRC |
3.20716 |
|
[BP] GO:0050890 |
None
|
APP, CHRM1, CHRNA7, CNR1, EGFR, GRM5, HTR2A, INSR, KIT, PTGS2 |
3.18036 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ADRB2, ALOX15, AURKB, BCL2, GPER1, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.16117 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CACNA1C, CHRM1, CNR1, CSNK2A1, EGFR, ERBB2, F2, GPER1, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
3.16019 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.1597 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
3.14361 |
|
[BP] GO:0010675 |
None
|
ESRRB, GPER1, INSR, PPARA, PTAFR, RORC, SRC |
3.11992 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADRA1D, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.11358 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK |
3.10989 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, CHRM1, CNR1, EGFR, ERBB2, F2, GPER1, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
3.10548 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F2, F3, FABP4, KDR, MET, MIF, PTGS2, SMAD3 |
3.09925 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.08674 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.08674 |
|
[BP] GO:0050866 |
negative regulation of cell activation
|
AXL, CNR1, CNR2, DUSP3, ERBB2, F2, GPER1, PRKCD |
3.08352 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, KIT, NR3C1, PRKCD, SRC |
3.07869 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, KIT, PRKCD, PTAFR, PTGS2 |
3.06376 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, GPER1, HTR5A, PTGS2 |
3.06186 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, F2, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, RORC, SMAD3, SRC |
3.06063 |
|
[BP] GO:0097755 |
None
|
ADRB1, ADRB2, EGFR, GPER1, PTAFR |
3.04588 |
|
[BP] GO:0050865 |
regulation of cell activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, ERBB2, F2, GPER1, MIF, PIK3CA, PRKCD, PTAFR, SRC |
3.04219 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, HSD17B3, HTR1A, PTAFR, TYR |
3.03577 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
3.02314 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GPER1, HTR2A, INSR, PPARA, PTAFR, RORC, SRC |
3.02065 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, ERBB2, F3, HTR2B, KDR, MMP12, TEK |
3.00453 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CHRNA7, CYP1B1, F3, GPER1, KDR, KIT, PTGS2, TEK |
3.00453 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, F2, FUT7, KIT, MIF, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.99812 |
|
[BP] GO:0010359 |
None
|
ABCB1, GRM5, PTAFR |
2.98248 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, ADRB2, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.973 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, KIT, SRC, TEK |
2.97077 |
|
[BP] GO:0070482 |
response to oxygen levels
|
BCL2, CHRNA7, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
2.96284 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
2.96284 |
|
[BP] GO:0006693 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
2.96284 |
|
[BP] GO:0006692 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
2.96284 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PTAFR, SRC |
2.95946 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3, SRC |
2.9478 |
|
[BP] GO:0098900 |
None
|
ADRA1A, CACNA1C, CNR1, CNR2, GPR35 |
2.93799 |
|
[BP] GO:0007611 |
None
|
APP, CHRNA7, CNR1, EGFR, GRM5, HTR2A, INSR, KIT, PTGS2 |
2.92352 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ADRB2, APP, AR, AXL, BCL2, CA2, CHRNA7, CNR1, CYP1B1, ESRRB, F3, GPER1, HTR2A, HTR2C, INSR, KDR, KIT, PIM1, PTGS2, SMAD3, SRC, TEK |
2.90845 |
|
[BP] GO:1904646 |
cellular response to amyloid-beta
|
ADRB2, APP, GRM5, IGF1R |
2.90245 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CHRNA7, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.89324 |
|
[BP] GO:0051588 |
None
|
CHRNA3, GPER1, GRIK5, HTR1A, HTR1B, HTR2C |
2.88871 |
|
[BP] GO:0043270 |
None
|
ABCB1, ADRB2, CHRM1, F2, GPER1, KCNH2, MIF, PRKCD, PTAFR |
2.88465 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.84637 |
|
[BP] GO:0050873 |
None
|
ADRB1, ADRB2, FABP4, PTGS2 |
2.84292 |
|
[BP] GO:0034764 |
None
|
ABCB1, ADRB2, CA2, F2, GPER1, KCNH2, PTAFR |
2.83318 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.83318 |
|
[BP] GO:0032409 |
None
|
ABCB1, ADRB2, APP, BCL2, GPR35, GRM5, MMP9, PRKCD, PTAFR |
2.83318 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, GPER1, INSR, MIF, SRC |
2.79994 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADRA1D, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.79933 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, SMAD3, SRC, TEK |
2.79169 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.77401 |
|
[BP] GO:0001997 |
None
|
ADRA1A, ADRB1 |
2.74051 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.74051 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.74051 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.73598 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.72873 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.72873 |
|
[BP] GO:0019371 |
None
|
PTGES, PTGS1, PTGS2 |
2.72873 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.71046 |
|
[BP] GO:0042307 |
positive regulation of protein import into nucleus
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3 |
2.70257 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.67984 |
|
[BP] GO:0046854 |
phosphatidylinositol phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.67984 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, AR, BCL2, CHRM1, CSNK2A1, EGFR, ERBB2, F2, GPER1, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.67443 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.67443 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.67181 |
|
[BP] GO:1904591 |
positive regulation of protein import
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3 |
2.65857 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.65483 |
|
[BP] GO:0006952 |
defense response
|
ADORA3, ALOX15, APP, AXL, BCL2, CNR2, F2, GPER1, HTR1A, HTR2C, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, SRC |
2.65066 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.63916 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.63916 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.63916 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.63916 |
|
[BP] GO:0042596 |
None
|
ADRB1, BCL2, HTR1A, HTR2C |
2.63794 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.63733 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTAFR, PTGES, PTGS2, SRC |
2.63733 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.63014 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.6229 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
ADRB2, APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCD, PTPN1 |
2.59922 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
2.59782 |
|
[BP] GO:0009266 |
None
|
ADRB1, ADRB2, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2 |
2.5972 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.59199 |
|
[BP] GO:0106027 |
None
|
APP, CHRNA7, IGF1R, INSR |
2.59199 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, GPER1, HTR1A, HTR2A, HTR2C |
2.59002 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, CNR2, HTR1B, HTR2A, PTGS2 |
2.58769 |
|
[BP] GO:0060402 |
None
|
ADRA1A, CACNA1C, HTR2A, HTR2B, HTR2C |
2.58769 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.56246 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.56246 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CHRNA7, CYP1B1, ERBB2, F3, GPER1, KDR, KIT, PTGS2, TEK, XDH |
2.54869 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, CHRM1, EGFR, ERBB2, F2, GPER1, PRKCD, PTGS2, SMAD3, SRC |
2.54653 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, ADRB2, MMP1, MMP12, MMP2, MMP9 |
2.53757 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CACNA1C, CHRM1, CHRNA3, CSNK2A1, EGFR, ERBB2, F2, GPER1, GRIK5, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.52861 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.52436 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7 |
2.52436 |
|
[BP] GO:0051100 |
negative regulation of binding
|
ADRB2, AURKB, CYP2D6, MET, PPARA, PRKCD, TNKS |
2.51981 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.51947 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, ERBB2, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.51501 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.49969 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PRKCD, SRC, TNKS, TNKS2 |
2.47266 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.47207 |
|
[BP] GO:0006936 |
None
|
ADRA1A, CHRM3, HTR1D, HTR2A, HTR2B, HTR7, KCNH2, PIK3CA |
2.46002 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, F2, MMP12, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC |
2.46 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, F2, PIK3CA, PIK3CB, PRKCD, SRC |
2.4588 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HSD17B3 |
2.44831 |
|
[BP] GO:0060079 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
2.44831 |
|
[BP] GO:0046834 |
lipid phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.44002 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.43861 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.43463 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, ADRB2, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, GRM3, GRM5, GRM8, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.41805 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
CNR2, CYP19A1, F2, GPER1, MIF, PPARA, PRKCD, SMAD3, TEK |
2.41712 |
|
[BP] GO:0051282 |
None
|
CACNA1C, F2, GPER1, HTR2A, HTR2B, HTR2C |
2.40082 |
|
[BP] GO:1900543 |
None
|
GRM3, GRM8, HTR1B, HTR1E, PPARA |
2.39422 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.38415 |
|
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1, HSD17B3 |
2.37434 |
|
[BP] GO:0045980 |
None
|
GRM3, GRM8, HTR1B, HTR1E, PPARA |
2.36896 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.36896 |
|
[BP] GO:0030814 |
None
|
ADRB1, GPER1, GRM3, GRM8, HTR1B, HTR1E |
2.34393 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
2.34275 |
|
[BP] GO:0046890 |
None
|
FABP3, GPER1, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
2.33817 |
|
[BP] GO:0038128 |
None
|
EGFR, ERBB2, PIK3CA, SRC |
2.33543 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
GPER1, HTR1B, MMP2, MMP9 |
2.33543 |
|
[BP] GO:0034765 |
None
|
ABCB1, ADRB2, APP, CACNA1C, F2, GPER1, GPR35, GRM5, KCNH2, MMP9, PTAFR |
2.33365 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.33365 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.33365 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.33365 |
|
[BP] GO:0001996 |
None
|
ADRA1A, ADRB1 |
2.33365 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.33365 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.33365 |
|
[BP] GO:0003099 |
None
|
ADRA1A, ADRB1 |
2.33365 |
|
[BP] GO:1905144 |
None
|
CHRNA3, CHRNA7 |
2.33365 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.33365 |
|
[BP] GO:0002025 |
None
|
ADRB1, ADRB2 |
2.33365 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, EGFR, ESR1, FLT3, GPER1, NR3C1, PTAFR, RORC, SRC |
2.32871 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ADRB2, ALPL, APP, AR, AXL, BCL2, CDC25B, CHRNA7, CYP1A1, EGFR, ERBB2, ESR1, ESRRB, FABP4, FLT3, FUT7, GLO1, HTR2B, KDR, KIT, MET, MIF, MMP2, MMP9, PGR, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.32483 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADRB1, ADRB2, AKR1B1, HTR2A, MET, PIK3CA |
2.31964 |
|
[BP] GO:0022898 |
None
|
ABCB1, ADRB2, APP, BCL2, GPR35, GRM5, MMP9, PTAFR |
2.30187 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DUSP3, ESR1, F2, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
2.28383 |
|
[BP] GO:0045598 |
None
|
GPER1, HTR2A, HTR2C, PTGS2, RORC, SMAD3 |
2.28383 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD |
2.28383 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, F2, MMP12, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC |
2.28383 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.28383 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.28383 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.28383 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.28383 |
|
[BP] GO:0022602 |
ovulation cycle process
|
BCL2, ESR1, KIT, PGR, SRC |
2.28383 |
|
[BP] GO:0060401 |
None
|
ADRA1A, CACNA1C, HTR2A, HTR2B, HTR2C |
2.28383 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.28287 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.27363 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.27363 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
2.26937 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, ERBB2, PPARA, SMAD3 |
2.2611 |
|
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, F2, FLT3, KIT |
2.2611 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.25993 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, HSD17B3, MIF, PTAFR, PTGES, PTGS1, PTGS2 |
2.24711 |
|
[BP] GO:1903793 |
None
|
ABCB1, MIF, PRKCD, PTAFR |
2.23787 |
|
[BP] GO:0002694 |
regulation of leukocyte activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, ERBB2, GPER1, MIF, PIK3CA, PTAFR, SRC |
2.2232 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.21521 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, EGFR, ERBB2, F2, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, SRC, TEK |
2.21516 |
|
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, F2, FLT3, KIT |
2.21465 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.21425 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.21425 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.21255 |
|
[BP] GO:0008016 |
None
|
ADORA3, ADRA1A, ADRA1B, ADRB1, CACNA1C, CHRM2, KCNH2, SLC1A1 |
2.20674 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.20549 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.20549 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.20549 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
ADRB2, CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PTPN1 |
2.20549 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADRA1A, ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, EGFR, F2, HSD11B2, HTR2A, KIT, MMP12, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC, TYR |
2.19129 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, SRC |
2.17091 |
|
[BP] GO:0043255 |
regulation of carbohydrate biosynthetic process
|
ESRRB, GPER1, INSR, PPARA, PTAFR |
2.17091 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B |
2.16994 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.14853 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.14651 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTAFR, PTGS2, TEK, TYR |
2.12073 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC |
2.11893 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
ADRB1, ADRB2, APP, AR, BCL2, INSR, PIK3CA, PIM1, TNKS2 |
2.11893 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.10533 |
|
[BP] GO:0034767 |
None
|
ABCB1, ADRB2, F2, GPER1, KCNH2, PTAFR |
2.10533 |
|
[BP] GO:0048731 |
system development
|
ACHE, ALPL, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, ERBB2, HSD17B3, MMP9, PIK3CA, SMAD3, SRC, TEK |
2.10375 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA3, ADRA1A, APP, AR, BCL2, CYP1B1, ERBB2, FABP3, GPER1, HSPA1A, PTGES, PTGS2, SMAD3, XDH |
2.10375 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ADRB2, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.09295 |
|
[BP] GO:0036211 |
protein modification process
|
ADRB2, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CHRM1, CHRM3, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.09295 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DUSP3, EGFR, GPER1, HSPA1A, INSR, MIF, PIM1, PTGS2, SMAD3, SRC, TNKS, TOP2A |
2.08506 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.08506 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.08506 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.08416 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.08416 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.08416 |
|
[BP] GO:1901529 |
None
|
ABCB1, PTAFR |
2.08416 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.08416 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.08416 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
2.08408 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, GPER1, IGF1R, INSR, PIK3CA, PRKCD, SRC, TNKS, TNKS2 |
2.07769 |
|
[BP] GO:0006633 |
None
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
2.07173 |
|
[BP] GO:0050877 |
None
|
APP, CHRM1, CHRM5, CHRNA7, CNR1, CNR2, CYP1B1, EGFR, GRM1, GRM5, GRM8, HTR2A, INSR, KIT, PTGS2, TYR |
2.04584 |
|
[BP] GO:0030815 |
None
|
GRM3, GRM8, HTR1B, HTR1E |
2.04507 |
|
[BP] GO:0034250 |
None
|
APP, CHRNA7, ERBB2, ESR1, PRKCD, PTAFR |
2.03483 |
|
[BP] GO:0060359 |
None
|
CHRNA3, CHRNA7, CNR1, HTR1B, PTAFR |
2.02864 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, EGFR, ESR1, KIT, PGR, PTGS2, SRC |
2.02864 |
|
[BP] GO:0031331 |
positive regulation of cellular catabolic process
|
ADRB2, ESRRB, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PTPN1 |
2.02104 |
|
[BP] GO:2001023 |
None
|
CHRNA3, CNR1, HTR1B, HTR2A, MET |
2.00802 |
|
[BP] GO:2000241 |
regulation of reproductive process
|
AR, CNR1, ESR1, INSR, PTAFR, SRC |
2.00512 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALOX15, APP, AXL, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, DUSP3, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, PTAFR, PTGS2, SLC1A1, SRC, TEK |
16.412 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTPN1, SLC1A1, SMAD3, SRC, TEK |
14.19 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, APP, AXL, CA4, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, CNR2, F10, F3, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, TEK |
14.0715 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, APP, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, CNR2, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, TEK |
12.498 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TYR |
12.1995 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADRA1A, ADRA1B, ADRB2, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, EGFR, ERBB2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, PTGS2, SLC1A1, SRC, TEK |
11.0662 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, NR3C2, PIK3CA, PIK3CB, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SRC, TEK, TYR |
10.7698 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.04731 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, ADRB2, APP, CHRNA3, CHRNA7, EGFR, ERBB2, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, NR3C2, SMAD3 |
6.42643 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, ADRA1B, APP, CHRNA3, CHRNA7, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
5.21821 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, ADRA1B, APP, CHRNA3, CHRNA7, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
5.18635 |
|
[CC] GO:0044853 |
plasma membrane raft
|
ADRA1A, ADRA1B, CHRNA3, CHRNA7, HTR2A, INSR, PTGS2, SRC |
4.93283 |
|
[CC] GO:0044456 |
None
|
ACHE, APP, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, SRC |
4.92611 |
|
[CC] GO:0042734 |
None
|
CNR1, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
4.9087 |
|
[CC] GO:0031224 |
None
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTGES, SLC1A1, TEK, TYR |
4.84024 |
|
[CC] GO:0043005 |
None
|
APP, CA2, CHRM1, CHRM2, CHRM3, CHRNA3, CNR1, CNR2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, PTGS2, SRC |
4.715 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, ADRA1B, APP, CHRNA3, CHRNA7, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
4.3511 |
|
[CC] GO:0016021 |
None
|
ABCB1, ABCG2, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ALPL, APP, AXL, CA12, CA14, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTGES, SLC1A1, TEK, TYR |
4.06994 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM3 |
4.05343 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, F10, F2, FLT3, GPER1, GRIA2, HSD11B1, HSD11B2, HSD17B2, HSD17B3, NR3C2, PTGES, PTGS1, PTGS2, PTPN1 |
3.67978 |
|
[CC] GO:0120025 |
None
|
AKR1B1, APP, CA2, CHRM1, CHRM2, CHRM3, CHRNA3, CNR1, CNR2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SRC, TEK |
3.58898 |
|
[CC] GO:0014069 |
None
|
CACNA1C, CHRM1, CHRNA3, GPER1, GRIK5, GRM1, GRM3, GRM5, SRC |
3.44578 |
|
[CC] GO:0099572 |
None
|
CACNA1C, CHRM1, CHRNA3, GPER1, GRIK5, GRM1, GRM3, GRM5, SRC |
3.44578 |
|
[CC] GO:0005901 |
caveola
|
ADRA1A, ADRA1B, HTR2A, INSR, PTGS2, SRC |
3.41193 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, GPER1, GRIA2, HSD11B1, HSD11B2, HSD17B2, HSD17B3, NR3C2, PTGES, PTGS1, PTGS2 |
3.29352 |
|
[CC] GO:0042995 |
cell projection
|
AKR1B1, APP, CA2, CHRM1, CHRM2, CHRM3, CHRNA3, CNR1, CNR2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SRC, TEK |
3.21782 |
|
[CC] GO:0097458 |
None
|
APP, CA2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRNA3, CNR1, CNR2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, HTR2B, HTR5A, INSR, PTGS1, PTGS2, SRC |
3.14817 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.14498 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.13347 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, ERBB2, GPER1, HSPA1A, KCNH2, PRKCD, PTGES, SRC, TNKS2, TYR |
2.94955 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADRA1A, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CACNA1C, CDC25B, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GRIA2, GRIA4, GRIK5, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2A, HTR4, HTR5A, INSR, KCNH2, KDR, KIT, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.79892 |
|
[CC] GO:0045202 |
None
|
ACHE, APP, CHRM1, CHRM2, CHRM3, CHRM5, EGFR, GRIA2, HTR2B |
2.6229 |
|
[CC] GO:0030425 |
None
|
CHRM1, CHRM2, CHRM3, CHRNA3, CNR2, GPER1, GRIA2, GRIK5, GRM1, HTR5A |
2.52162 |
|
[CC] GO:0030054 |
cell junction
|
ACHE, AKR1B1, APP, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, EGFR, GPER1, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2B, KDR, KIT, PRKCD, TEK |
2.32343 |
|
[CC] GO:0098802 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM1, INSR |
2.25665 |
|
[CC] GO:0005783 |
None
|
APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GPER1, GRIK5, HSD17B3, HSPA1A, HTR5A, KDR, PRKCD, PTGS2, PTPN1, XDH |
2.24518 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
CA2, CA4, CA9, CHRM3, EGFR, ERBB2, TEK |
2.1002 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.02864 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
27.6633 |
|
[MF] GO:0008227 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
25.3146 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
25.3146 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
24.7117 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AR, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SMAD3, TEK |
24.2473 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
22.6797 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
19.5305 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
18.7473 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
18.7473 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
18.7282 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
17.8692 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM3, CHRNA3, CHRNA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
17.4425 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.0895 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.0895 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.9712 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.9712 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, CHRM3, CHRNA3, CHRNA7, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.1717 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM3, CHRNA3, CHRNA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
13.3913 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, CHRM3, CHRNA3, CHRNA7, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
12.2721 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, CHRM3, CHRNA3, CHRNA7, EGFR, GPER1, HSD17B1, IGF1R, INSR, NQO2, NR3C1, SHBG |
11.4341 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC, SHBG |
11.38 |
|
[MF] GO:0004930 |
None
|
ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, CNR1, CNR2, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, PTAFR |
10.799 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.7816 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC, SMAD3, TNKS |
10.7698 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.7303 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC |
10.4562 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CHRM1, CHRM2, CHRM3, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, EGFR, ERBB2, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, SRC, TEK, TOP2A |
10.4345 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CHRM1, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, F10, F2, F3, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, PTGES, PTGS1, PTGS2, PTPN1, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
9.52177 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
8.80627 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.30556 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.30556 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.79495 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.43 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
7.43 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.32487 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, NQO2, PTGS1, PTGS2, TYR, XDH |
7.26486 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SHBG |
7.1282 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7 |
6.84623 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
6.82581 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR, KIT |
6.80606 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.52311 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.29109 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.18892 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.07713 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, XDH |
6.06792 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.92814 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.63032 |
|
[MF] GO:0004935 |
None
|
ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
5.3997 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TYR |
5.18635 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B2, HSD17B1, NQO2, PTGES, PTGS1, PTGS2, SRC, XDH |
5.01245 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
4.80367 |
|
[MF] GO:0004937 |
None
|
ADRA1A, ADRA1B, ADRA1D |
4.70527 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, XDH |
4.67478 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, SRC, TEK |
4.65902 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
4.4744 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, ADRB2, APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRB, F3, GRM5, HSPA1A, KCNH2, KIT, MET, MIF, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.35553 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.25742 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK |
4.17849 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.1145 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA3, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRM5, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.90088 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, ADRB2, AOX1, APP, BCL2, CHRNA7, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, FLT3, GRIK5, IGF1R, KCNH2, KDR, KIT, MET, MIF, MMP9, NQO2, PGR, PTGS2, SMAD3, TOP2A, TYR, XDH |
3.87242 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.79423 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
3.79423 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK |
3.67978 |
|
[MF] GO:0042166 |
None
|
ACHE, CHRM3, CHRNA3, CHRNA7 |
3.65289 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.58226 |
|
[MF] GO:0004936 |
None
|
ADRA1A, ADRA1B, ADRA1D |
3.5317 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.47627 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADRB1, ADRB2, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SHBG, SMAD3, SRC, TEK, TOP2A, XDH |
3.34668 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.31729 |
|
[MF] GO:0098960 |
None
|
CHRNA3, CHRNA7, GRM1, GRM5 |
3.30065 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
3.16051 |
|
[MF] GO:0005231 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.1199 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, KIT, SMAD3 |
3.10132 |
|
[MF] GO:0022824 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.04588 |
|
[MF] GO:0022835 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.04588 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADRA1A, ADRA1B, ADRB1, ADRB2, AOX1, AR, AXL, BCL2, CHRNA7, EGFR, ERBB2, FLT3, KCNH2, KIT, NQO2, PTGS2, SMAD3, TOP2A, TYR, XDH |
2.93799 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, ALOX15, AOX1, APP, AURKB, AXL, CSNK2A1, EGFR, ERBB2, F10, F2, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGES, SLC1A1, SRC, TEK, TOP2A, XDH |
2.85434 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK |
2.78182 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.74051 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.74051 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.74051 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.74051 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.74051 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, ADRB2, CHRNA7, GRIA2, INSR |
2.70257 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADRB2, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.54405 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.49928 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADRB2, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.45299 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, MET, PPARA, PTPN1, SMAD3 |
2.38205 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, XDH |
2.36867 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.33365 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.33365 |
|
[MF] GO:0004939 |
None
|
ADRB1, ADRB2 |
2.33365 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.33365 |
|
[MF] GO:0005230 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
2.3034 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.16994 |
|
[MF] GO:0005488 |
binding
|
ABCB1, ABCG2, ACHE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CHRM1, CHRM2, CHRM3, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRIA2, GRIK5, GRM1, GRM5, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.16586 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.12073 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, ADRB2, AOX1, BCL2, CHRNA7, FLT3, KCNH2, KIT, NQO2, PTGS2, SMAD3, TOP2A, TYR, XDH |
2.08644 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.08506 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.08506 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.08416 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.08416 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.08416 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.08416 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP2A |
2.02063 |
