| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR7, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, XDH |
21.3623 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HTR5A, IGF1R, INSR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
19.3899 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR5A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
18.0153 |
|
[BP] GO:0042221 |
response to chemical
|
ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TOP1, TRPV1, TYR |
17.6791 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
16.121 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
16.0954 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
14.9341 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, HSD11B2, HTR5A, NR3C1, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
14.4673 |
|
[BP] GO:0042493 |
response to drug
|
ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, HMGCR, HSD11B2, HTR2A, HTR2B, KDR, MMP3, NR3C1, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TOP1, TRPV1 |
14.3221 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.7592 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.5744 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
13.4864 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.352 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP2, MMP3, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.1349 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
13.1243 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, APP, AR, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PRKCA, PTAFR, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
12.6934 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP3, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
12.6624 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, DRD5, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, HTR5A, IGF1R, INSR, MMP2, NR3C1, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1 |
12.6459 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, PRKCE, PTGS2 |
12.5497 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, PRKCE, PTGS2 |
12.5497 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
12.3479 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
12.091 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
12.091 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR7, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP3, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TRPV1, TYR |
11.9769 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
11.9656 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.9261 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.9103 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.8234 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.82 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TRPV1 |
11.7968 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2A, HTR2B, KDR, MIF, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
11.7282 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP3, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TOP2A, TRPV1, TYR |
11.3821 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR5A, INSR, NR3C1, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TEK, TRPV1 |
11.3588 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA1A, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CDK6, CNR1, CNR2, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
10.8656 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ADRA1A, AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
10.8656 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, DRD1, DRD5, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TRPV1 |
10.8527 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.8306 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRA1A, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR5A, HTR6, HTR7 |
10.7011 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
10.6489 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, HTR5A, NR3C1, PRKCE, PTAFR, PTGS2, RORC, SRC, TYR |
10.4795 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, HTR2A, PTGS2 |
10.3977 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRA1A, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, SRC, TRPV1 |
10.3645 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
10.2783 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.2174 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.2174 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, ALOX12, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, PRKCA, PTAFR, PTGS2, TEK |
10.0439 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, MMP3, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
10.0245 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
9.99275 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
9.88644 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.66043 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.57602 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR2B, MIF, PIK3CA, PIM1, PPARA, PTAFR, PTGS1, PTGS2, TYR, XDH |
9.51677 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRA1A, AKR1B1, ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.51677 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.49718 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
9.49206 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.48123 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.47067 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
9.44359 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
9.44359 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.41867 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRA1A, CNR1, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR5A, HTR7 |
9.41607 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, AR, DRD2, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
9.4123 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
9.3855 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
9.38375 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
9.30797 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
9.30797 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TRPV1, XDH |
9.21638 |
|
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, DRD5, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
9.21601 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CNR1, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
9.20756 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
9.14996 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
9.14996 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
9.08826 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.0873 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, AR, DRD2, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
9.04634 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.97648 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.95407 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
8.89532 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, PRKCA, PRKCE, SLC22A1 |
8.63156 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.63156 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
8.56243 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD2, DRD3, DRD5, HSD11B2, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
8.56027 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
8.54222 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, KDR, MET, MIF, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
8.41223 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADRA1A, CA2, CA7, CNR1, CNR2, DRD2, PRKCE |
8.37276 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.3596 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.3596 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.32541 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.32541 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.32541 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, HTR2A, HTR2B, MMP2, PPARA, PRKCB, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
8.20538 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PGR, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
8.17175 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, MMP3, NR3C1, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TRPV1 |
8.17115 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1 |
8.16132 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.12576 |
|
[BP] GO:0050801 |
ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.12576 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MIF, MMP2, MMP3, MMP9, NR3C1, NUAK1, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
8.07721 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.03988 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR5A, HTR7 |
8.01919 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.00906 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA1A, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
8.00906 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
8.00906 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
8.00906 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.93448 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
7.91122 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.85802 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.85802 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.85802 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRIK5, HTR1A, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.81623 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, HMGCR, KDR, PRKCD, PRKCE, SRC |
7.79382 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, NR3C1, PTAFR, PTGS2, RORC, SRC, TRPV1 |
7.78452 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.77545 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ALOX12, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, MMP3, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.75025 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP3, MMP9, PRKCD, PTGS2, SRC |
7.71764 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.71328 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, HTR2B, MIF, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
7.65415 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, HMGCR, KDR, MET, MIF, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
7.61025 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.58883 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.58883 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA1A, ALOX12, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.58883 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, HMGCR, HTR2A, HTR2B, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
7.58883 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
7.49853 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA1A, ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
7.48372 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.47695 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRA1A, AR, AXL, BCL2, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PGR, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
7.46862 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, HMGCR, HTR1A, HTR2A, HTR2B, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
7.46205 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.45703 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, DUSP3, EGFR, HMGCR, HTR2A, HTR2B, KDR, MIF, PRKCA, PTPN1, SRC, TEK |
7.43929 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
7.40904 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
7.40904 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.37179 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.34074 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
7.33587 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX12, ALOX15, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
7.27149 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, HTR7, PGR, PPARA, PRKCG, RORC, SRC, TOP1, TOP2A |
7.24477 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
7.2432 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, EGFR, HMGCR, HTR2A, HTR2B, KDR, MIF, PRKCA, SRC, TEK |
7.23405 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
7.21887 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA1A, APP, CA2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, PTAFR, SIGMAR1, SRC |
7.21343 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.19964 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PGR, PRKCG, SLC1A1, TEK |
7.18537 |
|
[BP] GO:0055080 |
cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.16292 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.14569 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRA1A, AKR1B1, APP, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HTR1A, HTR2A, HTR2B, HTR7, INSR, PIK3CA, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
7.12034 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
7.09874 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
7.03695 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1 |
7.00971 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, HTR2A, HTR2B, KDR, PRKCE, SRC, TRPV1 |
6.98623 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.98623 |
|
[BP] GO:0099536 |
None
|
CNR1, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PRKCG, SLC1A1 |
6.98623 |
|
[BP] GO:0099537 |
None
|
CNR1, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PRKCG, SLC1A1 |
6.98623 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
6.98469 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ADRA1A, APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.92622 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
6.91879 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, GBA2, HMGCR, HTR1A, PTAFR, TYR |
6.82208 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, MET, MIF, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
6.72953 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.68844 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
6.65635 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.65635 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.64021 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HMGCR, HTR2A, INSR, PRKCG, PTGS2 |
6.57773 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.57773 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
6.57773 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, DRD1, DRD5, EGFR, ESR1, FLT3, GRM5, IGF1R, INSR, MMP2, NR3C1, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
6.5704 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, NR3C1, PRKCE, PRKCG, PTAFR |
6.55198 |
|
[BP] GO:0006811 |
None
|
ADRA1A, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, PPARA, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
6.52588 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.49321 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PGR, PRKCG, SLC1A1, TEK |
6.41679 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HMGCR, HTR2A, INSR, PRKCG, PTGS2 |
6.38968 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
6.30571 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CB, PRKCD, PTPN1, SRC |
6.28311 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
6.231 |
|
[BP] GO:0007268 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PRKCG, SLC1A1 |
6.22681 |
|
[BP] GO:0098916 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR6, HTR7, PRKCG, SLC1A1 |
6.22681 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, MET, MIF, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SRC, TEK |
6.20603 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
6.20603 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
6.17425 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGS1, PTGS2 |
6.15953 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, DRD5, HTR2A, PTGS2 |
6.13419 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.13419 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.13419 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, DRD5, PPARA, PTAFR |
6.08775 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS, TOP1 |
6.04942 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, HTR2B, IGF1R, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
6.02155 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PRKCD, SRC, TEK |
6.02051 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.00231 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, CNR1, DRD1, DRD2, DRD3, GPR35, GRM5, HTR1A, HTR2A, MIF, MMP9, PRKCD, PRKCE, PTAFR, PTGS2 |
5.95642 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.94247 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRA1A, ALOX15, DRD1, DRD5, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, PRKCD, PRKCE, PTAFR, PTGS2 |
5.85742 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD5, EGFR, GRM5, IGF1R, INSR, MMP2, MMP3, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
5.84244 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
5.80181 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.79426 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.79426 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.70031 |
|
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, TRPV1 |
5.69526 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
5.66931 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, DRD3, GPR35, HTR2A, MMP9, PRKCE, PTGS2 |
5.65081 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.6387 |
|
[BP] GO:0042310 |
None
|
ADRA1A, DRD5, HTR1A, HTR2A, HTR2B, HTR7 |
5.63841 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
5.62782 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS, TOP1 |
5.59779 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CNR2, CYP19A1, DRD1, DRD2, DRD3, HMGCR, MIF, PPARA, PRKCD, SMAD3, TEK |
5.58828 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
5.5755 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP3, MMP9, PRKCD, SRC |
5.56283 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
5.51966 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD5, EGFR, GRM5, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
5.49977 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.49814 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, FLT3, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1, TOP2A |
5.46836 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRA1A, APP, BCL2, CNR1, CNR2, DRD1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
5.43645 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP3, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.42879 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, HTR2A, HTR2B, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC, TRPV1 |
5.42031 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, HCAR2, HTR2B, INSR, MIF, MMP12, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
5.41898 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.39542 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.374 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.3461 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.3461 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
5.3461 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.34528 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.34528 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
5.32607 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
5.32013 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
5.26352 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, ALOX12, DRD1, DRD2, HTR2A, MET, PIK3CA, TRPV1 |
5.26346 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, HTR2A, HTR2B, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC |
5.23893 |
|
[BP] GO:0032787 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PPARA, PTGS1, PTGS2 |
5.23487 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
5.21378 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.1974 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
5.19034 |
|
[BP] GO:0007200 |
None
|
ADRA1A, DRD1, DRD2, DRD5, ESR1, GRM5, HTR2A, HTR2B |
5.16862 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX12, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
5.14712 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC |
5.14605 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, DRD3, DRD5, PRKCE, PRKCG, PTAFR |
5.13415 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP3, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.13397 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, HSD11B2, HSPA1A, HTR1A, MIF, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
5.11751 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
5.10821 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, MIF, PRKCA, PRKCE, SRC |
5.05401 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
5.03666 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
5.03615 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, MMP3, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.98361 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, PTAFR, SRC, TRPV1 |
4.90634 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, HSD11B2, NR3C1, PTAFR, PTGS2, SRC |
4.8999 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A, HTR2A, HTR2B |
4.8934 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP3, MMP9, PRKCD, SRC |
4.87406 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.86296 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, RORC, SMAD3, SRC, TRPV1 |
4.86296 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.85468 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.84356 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA1A, DRD2, DRD3, EGFR, GPR35, GRM1, HCAR2, HTR2A, PRKCA, PTAFR, PTGS2, SLC1A1, SMAD3, TRPV1 |
4.80091 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, GRM5, HMGCR, INSR, PTGS2 |
4.7787 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.77291 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, DRD5, EGFR, PPARA, SMAD3 |
4.77237 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, PTAFR, SRC |
4.728 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, SMAD3, SRC, TEK |
4.70819 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
4.7032 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, HTR2A, MIF, PRKCD, PRKCE, PTPN1, SRC |
4.69301 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MIF, PRKCD, PTGS2 |
4.69301 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, PRKCE, SMAD3, TRPV1 |
4.6681 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.65071 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
4.64852 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, GRM5, PTAFR |
4.64492 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, HTR2A, INSR, PPARA, PRKCA |
4.6439 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.6391 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.63589 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.5734 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PRKCD, SRC, TEK |
4.5734 |
|
[BP] GO:0097366 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5, MMP3 |
4.5585 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
4.535 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, HTR2A, INSR, PPARA, PRKCA |
4.5272 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, HTR2B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.51345 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.49654 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP3, MMP9, PRKCD, SRC |
4.48058 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTAFR, PTGS2 |
4.42313 |
|
[BP] GO:0001975 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5 |
4.41101 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.36359 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.35964 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, HTR1A, TYR |
4.35331 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
4.35123 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTAFR, PTGS2, SRC |
4.34308 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, PTGS1, RORC |
4.33853 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.32286 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.31236 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CB, PRKCD, PTPN1, SRC |
4.2845 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.28174 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.26023 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ADORA1, CA2, CA7, GRM5, MIF, PRKCD, PTAFR |
4.22088 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
4.21426 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD, PRKCE |
4.21426 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, MIF, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
4.21426 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR5A, HTR7 |
4.20269 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.20269 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, GRM8, HMGCR, HTR2A, INSR, PRKCG, PTGS2, TRPV1, TYR |
4.1962 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
4.1962 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, PRKCA, PRKCE |
4.1962 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, MIF, PTGS1, PTGS2 |
4.1962 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, MIF, PIK3CB, PTPN1, SRC |
4.18217 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TNKS, TOP2A |
4.18056 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7, PRKCE |
4.18056 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP3, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.16554 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, HTR5A, INSR, KDR, MMP9, PGR, PIK3CA, PIM1, PPARA, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
4.1382 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
4.12877 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.12877 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
4.11249 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.11097 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TNKS, TOP2A |
4.10143 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.07443 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, F3, HTR2B, KDR, MMP12, PGR, PRKCA, SMAD3, TEK, XDH |
4.07126 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, PGR, PTAFR, PTGS2, SRC, TOP2A |
4.06701 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A, TRPV1 |
4.06393 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
4.06393 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.05179 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
4.03618 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, MMP12, PPARA, PRKCD, SMAD3, TEK |
4.03618 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, DRD3, DRD5, PRKCE, PRKCG |
4.00843 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, AR, BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
4.00149 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
4.00149 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
4.00149 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.99844 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.98952 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, DRD3, DRD5, PRKCE, PRKCG, TRPV1 |
3.95929 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.94892 |
|
[BP] GO:0045907 |
None
|
ADRA1A, EGFR, HTR2A, PTAFR, PTGS2 |
3.94019 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.93725 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.93725 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
3.93351 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PRKCE, PTAFR, SRC |
3.91097 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC, TEK |
3.90838 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
3.90756 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.88504 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.85819 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
3.85819 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.85294 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.84861 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.83176 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.83176 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, GRIK5, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP3, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.83113 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.83023 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
3.8258 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HTR2B, HTR5A, KDR |
3.82513 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTAFR, PTGS2 |
3.77629 |
|
[BP] GO:0030817 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.7759 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PRKCG, RORC, TOP2A |
3.7759 |
|
[BP] GO:0060402 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.75347 |
|
[BP] GO:0006855 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.75347 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
3.75347 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
3.75131 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.7454 |
|
[BP] GO:0032409 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTAFR |
3.72426 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, DRD3, GPR35, HMGCR, HSPA1A, HTR2A, MMP9, PRKCB, PRKCE, PTGS2 |
3.72426 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
3.72426 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, HTR2A, INSR, KDR, MIF, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
3.71633 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA |
3.67629 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP3, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, XDH |
3.67544 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
3.6729 |
|
[BP] GO:0014075 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5 |
3.67025 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.64823 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.64763 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, HTR2A, HTR2B, PRKCE, TRPV1 |
3.63962 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.59761 |
|
[BP] GO:0015893 |
None
|
CA2, DRD1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.59698 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.58764 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.55248 |
|
[BP] GO:1903524 |
None
|
ADRA1A, EGFR, HTR2A, PTAFR, PTGS2, SLC1A1 |
3.54637 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
3.54172 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.52254 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.52254 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.5186 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.5186 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.51707 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, HMGCR |
3.51707 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.51662 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.49107 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGS2 |
3.49107 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.48691 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
3.48691 |
|
[BP] GO:0006810 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2A, HTR2B, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.46704 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.46704 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, HSPA1A |
3.44947 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.44547 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.41347 |
|
[BP] GO:0051234 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2A, HTR2B, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.41053 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.38723 |
|
[BP] GO:0040016 |
embryonic cleavage
|
PIK3CB, TOP1, TOP2A |
3.38625 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.3858 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.38489 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
3.36629 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD1, DRD2, DRD3, HTR2A |
3.36629 |
|
[BP] GO:0060401 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.36629 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.35617 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
3.35617 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.35377 |
|
[BP] GO:0030814 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.34758 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
3.34596 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.34596 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.34596 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.34148 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, ALOX12, DRD2, F10, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
3.32993 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.31256 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, NR3C1, PGR, SRC |
3.31256 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
3.30518 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.30447 |
|
[BP] GO:0051179 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2A, HTR2B, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TNKS2, TRPV1, XDH |
3.30087 |
|
[BP] GO:0030802 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.28728 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.26435 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.26313 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.26092 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
3.25775 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, KDR, MET, MIF, PRKCA, PTGS2, SMAD3 |
3.24915 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
3.24514 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TNKS |
3.23631 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.23631 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PRKCE, SRC |
3.23093 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.22539 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.22539 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.21708 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.21708 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DRD5, DUSP3, FABP4, GRM3, HMGCR, IGF1R, MMP9, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
3.20821 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, MIF, PRKCE, TNKS |
3.1914 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.186 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.186 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP3, MMP9, PTGS2 |
3.18441 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, PTGS2, TYR |
3.1826 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.1826 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.1826 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, HMGCR |
3.16747 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, MIF, PIK3CB, PTPN1, SRC |
3.15766 |
|
[BP] GO:0022898 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
3.15631 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
3.15524 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B, PRKCE |
3.15524 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.15247 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HMGCR, HTR2A, INSR, KDR, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK |
3.15247 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.15078 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, PRKCA, TEK |
3.14175 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
3.14175 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.13151 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, PTAFR |
3.13151 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTAFR, PTGS2 |
3.11157 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, PTAFR, SRC |
3.11157 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, NR3C1, PRKCE, PTAFR, RORC, SRC |
3.11157 |
|
[BP] GO:0040008 |
regulation of growth
|
ALOX12, APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
3.09441 |
|
[BP] GO:1900371 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.09261 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.07814 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
3.0733 |
|
[BP] GO:0030808 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.0733 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B |
3.07202 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
3.07194 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.06319 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
ALOX12, APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK |
3.05189 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
3.05141 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.04855 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3, HTR1A |
3.03831 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR2A, MET |
3.03568 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, MIF, PIK3CA, PIK3CB, PTAFR, PTGS1, PTGS2, TRPV1 |
3.02506 |
|
[BP] GO:0019933 |
None
|
ADRA1A, DRD1, DRD2, DRD3, DRD5, HTR5A |
2.98377 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.98181 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ADRA1A, ALPL, AXL, BCL2, CDK6, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, HMGCR, HSD11B2, HTR2A, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.97647 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC, TOP1 |
2.97647 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, HTR7, PPARA, RORC, TOP1 |
2.96414 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.94268 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR2A |
2.94268 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DRD2, DUSP3, ESR1, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC |
2.94224 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
2.93644 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.93644 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PGR, PTGS2, SRC |
2.91623 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
2.90814 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.90814 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.87148 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.86817 |
|
[BP] GO:0003014 |
None
|
ADORA1, ADRA1A, AKR1B1, BCL2, DRD2, HSD11B2 |
2.86494 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.85977 |
|
[BP] GO:0030799 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
2.85524 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, HTR2B, PRKCE |
2.838 |
|
[BP] GO:0061041 |
regulation of wound healing
|
ALOX12, F3, HMGCR, PRKCA, PRKCD, PRKCE, SMAD3 |
2.838 |
|
[BP] GO:0045785 |
positive regulation of cell adhesion
|
ALOX12, ALOX15, CDK6, KDR, PIK3CA, PRKCA, PRKCE, PTAFR, SMAD3, SRC, TEK |
2.82269 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.82269 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.82269 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.82269 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.82269 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.82269 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.82269 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR2B |
2.82269 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.82269 |
|
[BP] GO:0019229 |
None
|
ADRA1A, EGFR, HTR2A, PTAFR, PTGS2 |
2.81958 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.80727 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTAFR, PTGS2, SRC |
2.79667 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.79667 |
|
[BP] GO:0042220 |
None
|
CNR1, DRD2, DRD3, DRD5 |
2.79246 |
|
[BP] GO:0045777 |
None
|
ADORA1, ADRA1A, CNR1, HSD11B2 |
2.79246 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.7919 |
|
[BP] GO:0031279 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
2.7919 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.79113 |
|
[BP] GO:0019935 |
None
|
ADRA1A, DRD1, DRD2, DRD3, DRD5, HTR5A |
2.79061 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.78539 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.76984 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.76984 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.76984 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.76984 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.76906 |
|
[BP] GO:0051339 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
2.76401 |
|
[BP] GO:0007194 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.74803 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.74803 |
|
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.73329 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, DRD5, EGFR, ESR1, PGR, PTGS2, SRC |
2.72312 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC |
2.7224 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.72049 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.72049 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AR, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HTR2B, KDR, MET, MIF, MMP2, MMP9, PGR, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.706 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, PRKCD, PTGS2 |
2.70493 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.70036 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.68566 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, PRKCD, SRC |
2.68355 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.67628 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.67628 |
|
[BP] GO:0050865 |
regulation of cell activation
|
ALOX12, APP, AXL, BCL2, CNR1, CNR2, DUSP3, MIF, PIK3CA, PRKCA, PRKCD, PTAFR, SRC |
2.67628 |
|
[BP] GO:0048167 |
None
|
ADORA1, APP, DRD1, DRD2, DRD5, GRM5, PTGS2 |
2.67348 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PTAFR, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.67022 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, MIF, MMP12 |
2.66996 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9, TRPV1 |
2.66949 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, PRKCE, SMAD3, TEK |
2.66949 |
|
[BP] GO:0031280 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.6564 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.6481 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.6481 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, NR3C1, PGR, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.62664 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE |
2.62664 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, MET, MMP1, MMP3, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.62664 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.62635 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.62635 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.62635 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.62635 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.62635 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.62597 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.61599 |
|
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.6139 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, INSR, NR3C1, PRKCD, PRKCE, SRC |
2.60579 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.60107 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.59901 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, CNR1, HCAR2, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, SRC |
2.57661 |
|
[BP] GO:0051350 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.5712 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR |
2.5712 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.5712 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX12, ALOX15, CYP19A1, HMGCR, PTAFR, TYR |
2.5543 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PRKCG, PTPN1, SRC |
2.55048 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.54466 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.53683 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.53683 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR2A |
2.53683 |
|
[BP] GO:0051282 |
None
|
DRD1, DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
2.5367 |
|
[BP] GO:0007190 |
None
|
ADORA3, DRD1, DRD5, PRKCA |
2.53186 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.53186 |
|
[BP] GO:0032412 |
None
|
APP, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.51745 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA1A, DRD2, EGFR, HTR2A, PTAFR, PTGS2, SLC1A1 |
2.51745 |
|
[BP] GO:0007189 |
None
|
ADRA1A, DRD1, DRD2, DRD3, DRD5 |
2.49567 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.49567 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.49149 |
|
[BP] GO:0031334 |
positive regulation of protein complex assembly
|
ALOX15, ESR1, HSPA1A, MET, MMP1, MMP3, PRKCE, SRC |
2.4812 |
|
[BP] GO:1903034 |
regulation of response to wounding
|
ALOX12, F3, HMGCR, PRKCA, PRKCD, PRKCE, SMAD3 |
2.46962 |
|
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.46962 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.45286 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.45286 |
|
[BP] GO:0003073 |
None
|
AR, DRD3, DRD5, HSD11B2 |
2.45108 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.45108 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, NR3C1, SRC |
2.44525 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GRM3, GRM8, HMGCR, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
2.44213 |
|
[BP] GO:0010563 |
None
|
DRD2, DRD3, DUSP3, FABP4, GRM3, GRM8, HMGCR, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
2.43617 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.43617 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.43617 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GRM3, GRM8, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCG, PTAFR, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.42894 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.42894 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.42894 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.42894 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.42894 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.42894 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.42894 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.42894 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, HMGCR, MIF, PTAFR, PTGS1, PTGS2 |
2.42189 |
|
[BP] GO:0034762 |
None
|
APP, BCL2, CA2, DRD1, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.42189 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, GRM5, HTR2A, MIF, PTPN1, SRC |
2.41138 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.38754 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.38754 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B |
2.38754 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.38754 |
|
[BP] GO:0042060 |
None
|
ALOX15, DRD5, EGFR, PPARA, SMAD3 |
2.38412 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.37532 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2 |
2.34911 |
|
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.33319 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GRM1, GRM5, PRKCE |
2.32567 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.31423 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.31213 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.31213 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.31213 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.31213 |
|
[BP] GO:0070542 |
None
|
FABP3, PRKCE, PTAFR, PTGS2, SRC |
2.31213 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, APP, AR, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, PTGS2, SMAD3, XDH |
2.29296 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, GRIK5, HMGCR, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.29056 |
|
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.28844 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.28541 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, MMP12, NR3C1, PPARA, PRKCA, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1 |
2.28203 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B |
2.27705 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, TNKS2 |
2.27299 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, MIF, PIK3CB |
2.26802 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.26802 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.26802 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.26656 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC |
2.25001 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.24807 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, PRKCD, PTAFR, PTGS2 |
2.24807 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.24807 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.24807 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.24807 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.24807 |
|
[BP] GO:0090330 |
regulation of platelet aggregation
|
ALOX12, PRKCA, PRKCD |
2.24807 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.24807 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR2B |
2.24807 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.24804 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, HMGCR, INSR, KDR, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, XDH |
2.24467 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.23996 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.2356 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRA1A, APP, CSNK2A1, DRD2, EGFR, ESR1, F3, HSPA1A, HTR2A, HTR2B, MMP9, NUAK1, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.2204 |
|
[BP] GO:0001936 |
None
|
F3, HTR2B, KDR, PRKCA, TEK, XDH |
2.2062 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.2062 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.20398 |
|
[BP] GO:0006633 |
None
|
ALOX12, ALOX15, MIF, PTGS1, PTGS2 |
2.18736 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.18736 |
|
[BP] GO:0001938 |
None
|
F3, HTR2B, KDR, PRKCA, TEK |
2.18736 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.18736 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.18736 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.18736 |
|
[BP] GO:0007617 |
None
|
APP, DRD1, DRD5 |
2.18736 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.18736 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD2, DRD3, HTR2A |
2.18606 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HSPA1A, HTR2B, MIF, MMP12, PTAFR, PTGS2, SMAD3, SRC |
2.18294 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.17477 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.17477 |
|
[BP] GO:0001994 |
None
|
ADRA1A, DRD5 |
2.17477 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.17477 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.17477 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.17477 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.17477 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.17477 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.16314 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, DRD5, EGFR, HTR2B |
2.15295 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.14219 |
|
[BP] GO:2000241 |
regulation of reproductive process
|
AR, CNR1, ESR1, INSR, PTAFR, SRC |
2.13813 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.13201 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.13201 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.12877 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.11866 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, GRIK5, HTR1A |
2.11286 |
|
[BP] GO:0030534 |
None
|
APP, DRD1, DRD2, DRD3, HTR2A, PPARA |
2.10969 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, XDH |
2.10969 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP1, MMP12, MMP2, MMP3, MMP9, PIK3CB, SRC, XDH |
2.10949 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.07408 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.07408 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.07408 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.07408 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, DRD1, HTR1A, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS1, PTGS2, SRC, TRPV1 |
2.05851 |
|
[BP] GO:0040007 |
None
|
ADRA1A, APP, AR, BCL2, CYP19A1, ESR1, SMAD3, SRC, TNKS2 |
2.05735 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUT7, HSPA1A, MIF, MMP9, PRKCB, PRKCD, PRKCE, PTAFR, RORC, SMAD3, TRPV1 |
2.05428 |
|
[BP] GO:0034766 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.03264 |
|
[BP] GO:0051259 |
None
|
ACHE, AR, HMGCR, IGF1R, INSR, MIF, SIGMAR1, SLC1A1, SLC22A1, TEK, TRPV1 |
2.03255 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.02513 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.02513 |
|
[BP] GO:0051194 |
None
|
ESRRB, HTR2A, INSR |
2.01984 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.01984 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2 |
2.01984 |
|
[BP] GO:0050996 |
None
|
PPARA, PRKCD, PRKCE |
2.01984 |
|
[BP] GO:0031349 |
positive regulation of defense response
|
CNR1, EGFR, FABP4, HSPA1A, MMP12, MMP2, PRKCD, PRKCE, PTGS2, SRC |
2.01498 |
|
[BP] GO:0098900 |
None
|
ADRA1A, CNR1, CNR2, GPR35 |
2.0138 |
|
[BP] GO:0048146 |
positive regulation of fibroblast proliferation
|
CDK6, EGFR, ESR1, MIF |
2.0138 |
|
[BP] GO:0019233 |
None
|
CNR1, CNR2, GRM1, PTGS2 |
2.0138 |
|
[BP] GO:0015696 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
2.0138 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.0138 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.0136 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX12, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1 |
11.8875 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, APP, AXL, CA4, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
11.4699 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, TYR |
10.4577 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, APP, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
9.99275 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRA1A, ALOX15, APP, AXL, CA2, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PRKCG, PTAFR, PTGS2, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
9.45247 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, ADRA1A, CA2, CA4, CA9, CNR1, DRD1, DRD2, DRD5, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, PRKCG, PTGS2, SIGMAR1, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
8.42975 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C2, PIK3CA, PIK3CB, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TEK, TRPV1, TYR |
7.23405 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, HTR5A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SIGMAR1, XDH |
4.41542 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PRKCG, PTGS2, SRC, TEK |
4.40098 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PRKCG, PTGS2, SRC, TEK |
4.31236 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, SIGMAR1 |
4.02978 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR5A, INSR, KDR, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.95619 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1, SIGMAR1 |
3.9308 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CNR1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SIGMAR1, SLC22A2, SRC, TRPV1 |
3.90786 |
|
[CC] GO:0097060 |
None
|
CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SIGMAR1, TRPV1 |
3.87608 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, CA2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, HTR2B, HTR5A, INSR, PRKCG, PTGS1, PTGS2, SIGMAR1, SLC22A2, SRC, TOP1, TRPV1 |
3.85819 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.8258 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, CA2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, PRKCG, PTGS2, SRC |
3.7759 |
|
[CC] GO:0014069 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SIGMAR1, SRC |
3.57981 |
|
[CC] GO:0099572 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SIGMAR1, SRC |
3.57981 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.09441 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.07313 |
|
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.06713 |
|
[CC] GO:0031224 |
None
|
ACHE, ADORA1, ADORA3, ADRA1A, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TEK, TRPV1, TYR |
2.8407 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.82269 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, NR3C2, SMAD3 |
2.79667 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CNR1, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SIGMAR1, SRC, TRPV1 |
2.7919 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CNR1, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SIGMAR1, SRC, TRPV1 |
2.7919 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TNKS2, TYR |
2.62445 |
|
[CC] GO:0005901 |
caveola
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.52086 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR5A, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.51417 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.50821 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.44525 |
|
[CC] GO:0043226 |
organelle
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR5A, HTR6, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.43231 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.42189 |
|
[CC] GO:0016021 |
None
|
ADORA1, ADORA3, ADRA1A, ALPL, APP, AXL, CA12, CA14, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TEK, TRPV1, TYR |
2.39623 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, SLC22A1, TEK |
2.24208 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, INSR, SRC, TRPV1 |
2.24208 |
|
[CC] GO:0031090 |
None
|
ADRA1A, ALOX5, APP, BCL2, CA4, CNR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD5, EGFR, FUT7, GBA2, GRIA2, GRIA4, HMGCR, INSR, PGR, PRKCA, PTAFR, PTGS1, PTGS2, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TYR |
2.20061 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.13201 |
|
[CC] GO:0044853 |
plasma membrane raft
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.09268 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
22.3061 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
17.8751 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SIGMAR1, TEK, TRPV1 |
17.5644 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SIGMAR1, TEK, TRPV1 |
15.8699 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SIGMAR1, TEK, TRPV1 |
15.6235 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PRKCE, PTAFR, RORC, SIGMAR1, SMAD3, TEK, TRPV1 |
15.5989 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.3959 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
13.9147 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
13.2268 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
12.5876 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, FLT3, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SIGMAR1, SRC, TEK, TOP1, TOP2A, TRPV1 |
11.3691 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA1A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, TEK, TRPV1 |
11.3691 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, SIGMAR1, TEK, TRPV1 |
11.3691 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
9.75492 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.36039 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.31629 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
9.04634 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC |
8.76333 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
8.69942 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5, HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
8.17175 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
8.17175 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.48372 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.38029 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, XDH |
7.19964 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.99548 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.99548 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
6.89487 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
6.56911 |
|
[MF] GO:0008227 |
None
|
ADRA1A, DRD2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.50045 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
6.32449 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
6.32449 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.32449 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
6.26204 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.231 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.22681 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA1A, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, PTAFR, SIGMAR1 |
6.15612 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.13419 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.13419 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
6.02583 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TRPV1 |
5.96009 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.73317 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
5.63841 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.45994 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.45567 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TYR |
5.3065 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
5.23893 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B2, HSD17B1, NQO2, PTGS1, PTGS2, SRC, XDH |
5.19034 |
|
[MF] GO:0099528 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
4.96877 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
4.8916 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
4.7787 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.72895 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
4.5585 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
4.51205 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.31236 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
4.2738 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, MET, MIF, NR3C1, PGR, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.22746 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
4.21426 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.20269 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.18056 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, EGFR, F10, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, SLC1A1, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
3.98537 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
3.88428 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.77629 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
3.73925 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.59761 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
3.5123 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, TOP1 |
3.4749 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.46704 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
3.45642 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
3.45373 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
3.3563 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
3.316 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, MET, MIF, MMP9, NQO2, PGR, PTGS2, SLC22A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
3.28733 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.28728 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
3.1826 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.07202 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.07202 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.07202 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.06319 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.00202 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.00202 |
|
[MF] GO:0015238 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
2.91219 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.88653 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.82269 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.82269 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.82269 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.82269 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.82269 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.82269 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.82269 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.75333 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.72049 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.67628 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.62685 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F10, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK, TOP1 |
2.56078 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, NR3C1, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.54197 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, NR3C1, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.53713 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.52804 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.42894 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.42894 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.42894 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.42894 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.42894 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.42894 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.42894 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.42894 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.42894 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.42894 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.42894 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.31213 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.27705 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.18736 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.18736 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.17477 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.17477 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.17477 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.17477 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.15871 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.15451 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.15295 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.12849 |
|
[MF] GO:0051213 |
dioxygenase activity
|
ALOX12, ALOX15, ALOX5, PTGS1, PTGS2 |
2.11286 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.06542 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.03583 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.0293 |
