| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, DRD3, EGFR, ESR1, F10, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
16.4094 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MMP2, MMP3, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TOP1, TYR |
16.0654 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.6196 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.6196 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ESR1, FABP3, HMGCR, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCD, PTAFR, PTGS2, RORC, SRC, TEK, TYR |
15.3521 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
15.1591 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
15.1231 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, POLB, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
14.6699 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, ESR1, FABP3, FABP4, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1 |
13.6229 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, EGFR, ERBB2, F10, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
13.6176 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, F10, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
13.1473 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
12.9735 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, BCL2, CDC25B, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PTAFR, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
12.9282 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, ALPL, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP3, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TYR |
12.6521 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ESR1, F10, FABP4, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP3, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TOP1, TYR |
12.0432 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, F10, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP3, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.9253 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.7922 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.5799 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD3, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.3951 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, BCL2, CA9, CNR1, CNR2, CYP1A1, CYP1B1, DRD3, EGFR, FABP3, HMGCR, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, MMP3, NR3C1, POLB, PRKCD, PTAFR, PTGS2, SRC, TOP1 |
11.3504 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD3, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.3085 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ERBB2, ESR1, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MMP2, NR3C1, PPARA, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TEK |
11.0306 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.8813 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FUT7, HMGCR, HSPA1A, HTR2B, HTR2C, MIF, PIK3CA, PIM1, PPARA, PTAFR, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.8578 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, NR3C1, PTAFR, PTGS2, RORC, SRC, TYR |
10.6854 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, FABP3, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.6854 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, FABP3, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.6854 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ESR1, FLT3, HSD11B2, HTR1B, HTR5A, NR3C1, PTAFR, PTGS2, RORC, SRC, TEK, TYR |
10.6399 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, INSR, KIT, NR3C1, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK |
10.629 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK |
10.559 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, FLT3, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PTAFR, PTGS2, TEK |
10.4957 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
10.4204 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
10.2682 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
10.202 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.1325 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
10.0919 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
9.98623 |
|
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
9.82341 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PTGS2, RORC, SRC, TEK |
9.66511 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRB1, CHRM2, CNR1, CNR2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
9.54191 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
9.44066 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP3, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.38335 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
9.22215 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
9.15728 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
9.13474 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
9.13474 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
9.13474 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DUSP3, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC, TEK, XDH |
9.12695 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
9.12627 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
9.10874 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
9.10701 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, FABP3, FABP4, FUT7, HMGCR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1 |
8.98028 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
8.96241 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.8684 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.86592 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRB1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.83212 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.82724 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CACNA1C, CNR1, DRD3, EGFR, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PIK3CB, PTGS2, SRC |
8.82724 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
8.77486 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCD, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK |
8.74357 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, ERBB2, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC |
8.68898 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD3, EGFR, HMGCR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, POLB, PPARA, PTAFR, PTGS2, SMAD3, SRC, TEK, TYR |
8.65398 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
8.4656 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CACNA1C, CNR1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C |
8.3428 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CYP1A1, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
8.33123 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.28184 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
8.17573 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
8.11669 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, KIT, MMP3, MMP9, PRKCD, PTGS2, SRC |
8.11669 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.08555 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCD, PTAFR, PTGS2, PTPN1, SRC, TEK, TOP1, XDH |
8.08555 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.98244 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PTGS2, SRC, TEK |
7.97694 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRB1, AKR1B1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD3, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, SMAD3, SRC |
7.9757 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
7.84038 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRB1, APP, CA2, CHRM2, CNR1, CNR2, DRD3, ESR1, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, PTAFR, SRC |
7.80712 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, ALPL, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CBR1, CDC25B, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, FUT7, HMGCR, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
7.76719 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.75947 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD3, EGFR, ERBB2, F10, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.75366 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
7.6706 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.66757 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MIF, MMP2, MMP3, MMP9, NR3C1, NUAK1, PIK3CA, POLA1, POLB, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC |
7.62663 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
7.60883 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.60095 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCD, PTAFR, PTGS2, PTPN1, SRC, TEK, TOP1, XDH |
7.59845 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
7.56439 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.51371 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
7.51129 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ERBB2, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TYR |
7.46925 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DUSP3, EGFR, ERBB2, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PTPN1, SRC, TEK |
7.46925 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APP, BCL2, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.46439 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
7.37743 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.32125 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.30757 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.23262 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD3, HMGCR, HTR1B, HTR1D, KDR, POLB, PRKCD, SRC |
7.23262 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, PIK3CA, POLB, PPARA, SMAD3, SRC, TEK, TYR |
7.22161 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRB1, AR, CNR1, DRD3, HSD11B2, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
7.18468 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
7.09847 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
7.0722 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
7.0722 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
7.07074 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRB1, CHRM2, CNR1, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
6.99396 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.94003 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
6.89459 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTGS2, PTPN1, SRC, TEK, XDH |
6.74232 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APP, BCL2, CACNA1C, CYP19A1, CYP1B1, EGFR, ERBB2, F10, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.72017 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
6.70524 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD3, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
6.62447 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APP, CNR1, CNR2, DRD3, EGFR, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, INSR, MMP2, MMP3, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK, TYR |
6.62447 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APP, BCL2, CYP19A1, CYP1B1, EGFR, ERBB2, F10, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.60863 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTAFR, PTGS2, SRC |
6.57058 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD3, DUSP3, EGFR, ERBB2, ESR1, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.56563 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD3, DUSP3, EGFR, ERBB2, ESR1, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.54012 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DRD3, EGFR, ERBB2, ESR1, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
6.44017 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APP, CNR1, CNR2, DRD3, EGFR, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PTAFR, PTGS2, SRC, TEK, TYR |
6.44017 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
6.39207 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, SRC, TEK, TOP1 |
6.38494 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD3, EGFR, ESR1, HTR7, KIT, PGR, PPARA, RORC, SRC, TOP1 |
6.33953 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.33838 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD3, EGFR, ESR1, FABP3, FABP4, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, SMAD3 |
6.32831 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.27299 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, HSD11B2, HSPA1A, HTR1A, HTR2C, KIT, MIF, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.27299 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
6.19951 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRB1, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM2, CNR1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, GPR35, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TEK, XDH |
6.13559 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTAFR, PTGS2 |
6.08268 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, DRD3, EGFR, HTR1B, HTR2A, KIT, PTGS2 |
6.0706 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, DRD3, EGFR, HTR1B, HTR2A, KIT, PTGS2 |
6.0706 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TEK |
6.02529 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
6.01865 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CACNA1C, CNR1, DRD3, EGFR, ERBB2, HCAR2, HMGCR, HTR2B, HTR2C, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
6.00715 |
|
[BP] GO:0042310 |
None
|
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
5.99961 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
5.9772 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRB1, ALOX15, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PRKCD, PTAFR, PTGS2 |
5.96992 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, AR, BCL2, CNR1, CNR2, CYP19A1, DRD3, DUSP3, EGFR, ERBB2, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.96992 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRB1, AKR1B1, APP, BCL2, CNR1, CNR2, CYP1B1, DRD3, EGFR, HMGCR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KIT, PIK3CA, PTAFR, PTGS2, SRC, TEK, TYR |
5.9509 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTAFR, PTGS2, SRC |
5.9509 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
5.8909 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.88413 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
5.83712 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
5.83644 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.82758 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD3, HTR2A, HTR2B, HTR2C, KDR, SRC |
5.82076 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CYP1B1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP3, MMP9, NR3C1, PIK3CA, PRKCD, PTAFR, PTGS2, RORC, SRC |
5.81314 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
5.76614 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, HTR1B |
5.76493 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRB1, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DRD3, EGFR, ERBB2, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, KIT, MET, MIF, NUAK1, PIK3CA, PIK3CB, POLB, PRKCD, PTAFR, PTPN1, SRC, TEK |
5.75307 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, HCAR2, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PTAFR, SRC |
5.72557 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APP, AR, EGFR, ERBB2, ESR1, FLT3, HTR1B, IGF1R, INSR, KIT, MMP2, NR3C1, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
5.72096 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRB1, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD3, EGFR, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, KDR, KIT, MET, MIF, MMP12, MMP9, PIM1, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.72096 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.71265 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
5.69736 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, CACNA1C, CNR1, DRD3, GPR35, HTR1A, HTR1B, HTR2A, MIF, MMP9, PRKCD, PTAFR, PTGS2 |
5.68296 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRB1, AR, AXL, BCL2, CACNA1C, CHRM2, CNR1, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PTGS2, TEK |
5.58314 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.56696 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, GPR35, HCAR2, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
5.56696 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
5.56129 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, FABP4, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, MMP3, NUAK1, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.5395 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.53333 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, EGFR, HTR1B, KDR, MMP3, NR3C1, PRKCD, PTAFR, PTGS2, SRC |
5.49241 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP3, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.49118 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
5.48796 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
5.48796 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
5.48796 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
5.38663 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, NR3C1, PTAFR, PTGS2, RORC, SRC |
5.38585 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
5.35007 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.30222 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, HCAR2, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PTAFR, SRC |
5.29696 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, FLT3, HSD11B1, HSD17B2, HTR5A, INSR, KDR, KIT, MMP9, PGR, PIK3CA, PIM1, POLB, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
5.28803 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD3, GPR35, HTR1B, HTR2A, MMP9, PTGS2 |
5.24412 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRB1, APP, AR, AURKB, BCL2, CDC25B, EGFR, ERBB2, ESR1, FLT3, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
5.22183 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRB1, APP, AURKB, BCL2, CDC25B, EGFR, ERBB2, ESR1, FLT3, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
5.18693 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.17014 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
5.11555 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, CNR1, DRD3, PPARA, PTAFR |
5.09928 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
5.09612 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD3, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
5.08837 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
5.07284 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, DRD3, EGFR, GPR35, HCAR2, HTR2A, HTR2C, KIT, PTAFR, PTGS2, SMAD3 |
5.07033 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, EGFR, MMP3, MMP9, PRKCD, SRC |
5.0168 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.00685 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, XDH |
5.00055 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, GPR35, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
4.99003 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD3, EGFR, ERBB2, HCAR2, HTR2B, INSR, MIF, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
4.92227 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD3, EGFR, ESR1, FABP4, HMGCR, KDR, MET, MIF, MMP12, PPARA, PRKCD, PTGS2, SMAD3, TEK |
4.90803 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRB1, AR, CACNA1C, CHRM2, CNR1, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, TEK |
4.90335 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, DUSP3, ESR1, FABP4, GPR35, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCD, PTGS2, PTPN1, SRC |
4.8741 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD3, EGFR, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KIT, PPARA, PTGS2 |
4.86939 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.85288 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP3, MMP9, PRKCD, SMAD3, SRC, TEK |
4.84731 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, FABP4, HCAR2, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PGR, PIK3CA, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, XDH |
4.81889 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRB1, AR, CHRM2, CNR1, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, TEK |
4.80792 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.72437 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
4.71706 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, BCL2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
4.71307 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGS1, PTGS2, TBXAS1 |
4.69741 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CNR1, CNR2, CYP19A1, DUSP3, ERBB2, ESR1, HCAR2, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
4.63698 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, MMP3, PRKCD, PTGS2, SMAD3, XDH |
4.6304 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD3, HMGCR, HTR1A, PTAFR, TYR |
4.6304 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CBR1, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, GPR35, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
4.61173 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, CNR1, DRD3, EGFR, ERBB2, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
4.61082 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA |
4.58786 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
4.55526 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC, TEK |
4.53492 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, MMP3, MMP9, PRKCD, SRC |
4.53492 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
4.53492 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CACNA1C, CNR1, CSNK2A1, DRD3, EGFR, ERBB2, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
4.51293 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTAFR, PTGS2 |
4.49935 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, POLB, PPARA, PTGS2, SMAD3, SRC, TEK |
4.49122 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, HTR2A, KIT, MIF, PRKCD, PTPN1, SRC |
4.48995 |
|
[BP] GO:0007568 |
aging
|
AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MIF, POLB, PRKCD, PTGS2 |
4.48995 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, FABP3, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.45669 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
4.45579 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, ERBB2, PPARA, SMAD3 |
4.44461 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, KIT, MIF, PIK3CA, PIK3CB, POLB, PTAFR, PTGS1, PTGS2 |
4.41266 |
|
[BP] GO:0099536 |
None
|
CHRM2, CNR1, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
4.38729 |
|
[BP] GO:0099537 |
None
|
CHRM2, CNR1, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
4.38729 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.35046 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.28222 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, EGFR, HTR1B, HTR2A, PTGS2 |
4.28222 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, CNR1, DRD3, EGFR, ERBB2, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
4.26579 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
4.26575 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTAFR, PTGS2 |
4.25107 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, DRD3, EGFR, HCAR2, HMGCR, HTR2B, HTR2C, MIF, MMP12, SRC |
4.24079 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.2338 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.20441 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AXL, CYP1B1, EGFR, HSPA1A, MMP3, MMP9, PRKCD, SRC |
4.17313 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.16508 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, HMGCR, HTR2A, HTR2B, HTR2C, MIF, SRC |
4.14365 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, PPARA, PRKCD, PTGS2, SMAD3, TEK |
4.13889 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, KIT, MMP9, PTGS2 |
4.1336 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
4.1219 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, HTR1B, HTR2A, PTGS2 |
4.09152 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
4.09152 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.07503 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.05388 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
4.04627 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.03235 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, SMAD3 |
4.02215 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CACNA1C, CNR1, CYP19A1, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, HTR2C |
4.02215 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, BCL2, CNR1, CSNK2A1, EGFR, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCD, PTPN1, SMAD3 |
4.01907 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.00172 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
4.00172 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
3.99587 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.99587 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
3.97303 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, XDH |
3.9425 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.92779 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
3.91443 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD3, EGFR, HMGCR, HTR2A, INSR, KIT, PTGS2 |
3.90754 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, BCL2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
3.88762 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, HSD11B2, HSD17B2, INSR, KIT, MMP2, MMP9, PGR, PTAFR, PTGS2, SRC |
3.8773 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.8773 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.83924 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD3, HMGCR, MIF, PPARA, PRKCD, SMAD3, TEK |
3.81547 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCD, PTAFR, SMAD3, SRC, TEK |
3.80225 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APP, FABP3, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK |
3.79421 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.78655 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, NQO2, PTGS1, RORC |
3.78655 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
3.76384 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, RORC, SMAD3, SRC |
3.75774 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APP, EGFR, HTR1B, IGF1R, INSR, MMP2, MMP3, PRKCD, PTAFR, PTGS2, SRC |
3.74813 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.72667 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
3.71635 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD3, EGFR, HCAR2, PIK3CB, PTGS2 |
3.68564 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, EGFR, ERBB2, HCAR2, HTR2B, MIF, MMP12, PRKCD, PTGS2, SMAD3, SRC |
3.67994 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, HSD17B2, INSR, KIT, PGR, PTGS2, SRC |
3.6761 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, HMGCR, HSD11B2, HTR2A, KIT, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TYR |
3.6761 |
|
[BP] GO:0007268 |
None
|
CHRM2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
3.66304 |
|
[BP] GO:0098916 |
None
|
CHRM2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
3.66304 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK, TOP1 |
3.66209 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DRD3, DUSP3, EGFR, ERBB2, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.66209 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.65159 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP3, MMP9, PTGS2 |
3.63535 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
3.58348 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD3, EGFR, HMGCR, HTR2A, INSR, KIT, PTGS2 |
3.56531 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC |
3.55712 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PTAFR, SRC |
3.53264 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.53063 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ADORA1, CA2, CA7, MIF, PRKCD, PTAFR |
3.52867 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.52503 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.51597 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.51597 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.51597 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, KIT, PRKCD, PTAFR, PTGS2 |
3.50413 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.47549 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
3.47549 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.47072 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD3, EGFR, HCAR2, HTR2B, MIF, MMP12, PTAFR, SRC |
3.4678 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
3.44995 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA |
3.44882 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, HTR1A, HTR2C, KIT, MIF, PIK3CA, PIK3CB, POLB, PRKCD, PTAFR, PTGS1, PTGS2, SRC |
3.40601 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.36585 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.35962 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APP, EGFR, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC |
3.34002 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP3, FABP4, FLT3, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
3.32981 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, XDH |
3.32814 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD |
3.32814 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP3, NUAK1, PRKCD, PTGS2, PTPN1, XDH |
3.32407 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, XDH |
3.32012 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.31617 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
3.29744 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, EGFR, ERBB2, HCAR2, HTR2B, MIF, MMP12, PRKCD, PTGS2, SMAD3, SRC |
3.28945 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.28181 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP1, TYR, XDH |
3.27783 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, ERBB2, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
3.26093 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, EGFR, ERBB2, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, SRC, TEK |
3.25728 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CHRM2, CYP1A1, DRD3, EGFR, HSD11B2, HSPA1A, HTR2A, INSR, KDR, MET, MMP1, MMP12, POLA1, PRKCD, PTAFR, SMAD3, SRC, TOP1 |
3.24925 |
|
[BP] GO:0050678 |
None
|
AR, EGFR, ERBB2, HTR2B, KDR, MMP12, PGR, SMAD3, TEK, XDH |
3.24925 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
3.20001 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.1771 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD3, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, MMP9, PTGS2 |
3.1674 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD3, EGFR, HTR1B, NR3C1, PTAFR |
3.15498 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC |
3.13099 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, KIT, SRC |
3.13099 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRB1, APP, CSNK2A1, EGFR, ERBB2, ESR1, HSPA1A, HTR2A, HTR2B, KIT, MMP9, NUAK1, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.12334 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.12097 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
3.12031 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD3, HTR1B, HTR2A |
3.12031 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
3.10773 |
|
[BP] GO:0046854 |
phosphatidylinositol phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.10773 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ALPL, APP, AR, AXL, BCL2, CBR1, CDC25B, CYP1A1, EGFR, ERBB2, ESR1, FABP4, FLT3, FUT7, HMGCR, HTR2B, KDR, KIT, MET, MIF, MMP2, MMP9, PGR, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK |
3.09898 |
|
[BP] GO:0009266 |
None
|
ADORA1, ADRB1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2 |
3.0897 |
|
[BP] GO:0050708 |
None
|
ACHE, CACNA1C, CNR1, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, SRC |
3.08758 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APP, AR, AURKB, BCL2, CNR1, CSNK2A1, DRD3, DUSP3, ESR1, FABP4, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MIF, MMP12, MMP3, MMP9, NR3C1, PIK3CA, PPARA, PRKCD, PTGS2, PTPN1, RORC, SMAD3, SRC, XDH |
3.07742 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGS1, PTGS2 |
3.06994 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.06994 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.06994 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.06994 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
3.06994 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, POLA1, SMAD3 |
3.06223 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.06223 |
|
[BP] GO:0019637 |
organophosphate metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, ERBB2, HMGCR, HSPA1A, HTR2B, HTR2C, KIT, MET, PIK3CA, PIK3CB, PTAFR, PTGS2, XDH |
3.05304 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, PTAFR |
3.05259 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.05259 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, FUT7, KIT, MIF, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
3.05259 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, XDH |
3.0354 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
3.03165 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
3.03165 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, HMGCR, HTR2A, HTR2C, INSR, KDR, KIT, MIF, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, XDH |
3.02518 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
3.02518 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
3.02518 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
3.0146 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK |
2.98467 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD3, EGFR, HMGCR, KIT, PTGS2, TYR |
2.98141 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, EGFR, HTR2A, PTAFR, PTGS2 |
2.98141 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.97221 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, MMP1, MMP12, MMP2, MMP3, MMP9 |
2.97007 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, NR3C1, NR3C2, PGR, PPARA, RORC |
2.93901 |
|
[BP] GO:0002031 |
None
|
DRD3, HTR1B, HTR2B |
2.93312 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.93312 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.93312 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, BCL2, CYP1B1, PRKCD, SRC |
2.92898 |
|
[BP] GO:0042596 |
None
|
ADRB1, BCL2, HTR1A, HTR2C |
2.92304 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.91817 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM2, KIT, PTAFR, PTGS2 |
2.91817 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DUSP3, ESR1, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
2.8962 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.87671 |
|
[BP] GO:0045907 |
None
|
EGFR, HTR2A, PTAFR, PTGS2 |
2.87671 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APP, AURKB, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, INSR, MIF, SRC |
2.87428 |
|
[BP] GO:0046834 |
lipid phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.87245 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.86832 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, APP, BCL2, DRD3, PIK3CA |
2.86778 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, POLB, TEK, TYR |
2.84238 |
|
[BP] GO:0046890 |
None
|
FABP3, HMGCR, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
2.84238 |
|
[BP] GO:0045913 |
None
|
HTR2A, INSR, PPARA, PTAFR, SRC |
2.83935 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
2.83376 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.8336 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, EGFR, ESR1, KIT, PGR, PTGS2, SRC |
2.79802 |
|
[BP] GO:0051345 |
None
|
ADRB1, APP, EGFR, ERBB2, ESR1, HSPA1A, HTR2A, HTR2B, KIT, PRKCD, PTAFR, PTPN1, SMAD3, XDH |
2.79507 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.79375 |
|
[BP] GO:1903524 |
None
|
ADRB1, EGFR, HTR2A, PTAFR, PTGS2 |
2.78676 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, HTR2A, KIT, MIF, PTPN1, SRC |
2.75488 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
2.75418 |
|
[BP] GO:0050865 |
regulation of cell activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, ERBB2, MIF, PIK3CA, PRKCD, PTAFR, SRC |
2.75134 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, AKR1B1, HTR2A, MET, PIK3CA |
2.74459 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.73554 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.73554 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.73554 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.73554 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, ERBB2, HTR2B, KDR, MMP12, TEK |
2.7315 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, APP, AR, BCL2, CSNK2A1, DRD3, EGFR, ERBB2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3 |
2.72941 |
|
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.70966 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, EGFR, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.69997 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, EGFR, PTGS2 |
2.69167 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, NR3C1, SRC |
2.68386 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, HCAR2, HMGCR, MMP3, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, XDH |
2.67986 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
2.67597 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC |
2.66701 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.6426 |
|
[BP] GO:0051967 |
None
|
ADORA1, HTR1B, HTR2A |
2.6426 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
2.63531 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD3, HTR1B, HTR2A |
2.63527 |
|
[BP] GO:0022602 |
ovulation cycle process
|
BCL2, ESR1, KIT, PGR, SRC |
2.63527 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, KIT, MET, MMP1, MMP3, SMAD3, SRC, TEK |
2.62998 |
|
[BP] GO:0038128 |
None
|
EGFR, ERBB2, PIK3CA, SRC |
2.62731 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTAFR, PTGS2, SRC |
2.62731 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR, HMGCR |
2.62524 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.62524 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, ERBB2, PPARA, SMAD3 |
2.61331 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
2.59927 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CNR1, CNR2, CYP19A1, DUSP3, ERBB2, MIF, MMP12 |
2.59122 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, NR3C1, PGR, SRC |
2.58991 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD3, HTR1A, TYR |
2.58991 |
|
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.56598 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD3, EGFR, HTR1A, INSR, PTGS2, SMAD3 |
2.56271 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, EGFR, HCAR2, HTR2B, MIF, MMP12, SRC |
2.56271 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
2.56037 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.55398 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.55398 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
2.54502 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC |
2.54429 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.52664 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, SRC |
2.52348 |
|
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.52348 |
|
[BP] GO:0006650 |
glycerophospholipid metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.50463 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, MIF, PIK3CB |
2.50063 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.50063 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TYR |
2.49985 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.4913 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.4913 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.4913 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.4913 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.48621 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD3, EGFR, HMGCR, KIT, POLB, PTGS2, TYR |
2.4768 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTPN1, RORC, SMAD3, SRC |
2.4766 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.46381 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.46381 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.46381 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP3, MMP9, PIK3CB, PRKCD, PTPN1, SMAD3, SRC, TEK |
2.45962 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD3, EGFR, HTR7, PPARA, RORC, TOP1 |
2.45665 |
|
[BP] GO:0007612 |
None
|
APP, DRD3, HMGCR, INSR, KIT, PTGS2 |
2.45665 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B |
2.45658 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SMAD3, SRC |
2.45643 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
AR, EGFR, ESR1, FLT3, INSR, KIT, NR3C1, PRKCD, SRC |
2.45643 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, XDH |
2.44834 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
2.4336 |
|
[BP] GO:2000241 |
regulation of reproductive process
|
AR, CNR1, ESR1, INSR, PTAFR, SRC |
2.42651 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.42441 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP3, MMP9 |
2.42435 |
|
[BP] GO:0002694 |
regulation of leukocyte activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, ERBB2, MIF, PIK3CA, PTAFR, SRC |
2.42159 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, XDH |
2.41375 |
|
[BP] GO:0007200 |
None
|
CHRM2, ESR1, HTR2A, HTR2B, HTR2C |
2.40369 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
2.40204 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, HMGCR, HTR2A, HTR2C, INSR, KDR, KIT, PIM1, PTGS2, SMAD3, SRC, TEK |
2.38156 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, NR3C1, NR3C2, PGR, PPARA, RORC |
2.36448 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DRD3, EGFR, HSPA1A |
2.36373 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD3, HTR1B, HTR2A, MET |
2.36332 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, XDH |
2.36332 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, HMGCR, MIF, PTAFR, PTGS1, PTGS2 |
2.36183 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD3, HTR1B, HTR2A |
2.36183 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.36076 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGS2, SRC |
2.35995 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, EGFR, HCAR2, HTR2B, MIF, MMP12, PTAFR, SRC |
2.35389 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, EGFR, ESR1, FLT3, NR3C1, PTAFR, RORC, SRC |
2.35389 |
|
[BP] GO:0043434 |
None
|
FABP3, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK |
2.3515 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR |
2.34381 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, FABP4, KDR, MET, MIF, PTGS2, SMAD3 |
2.34308 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC |
2.34308 |
|
[BP] GO:0008542 |
None
|
APP, DRD3, HMGCR, KIT |
2.3344 |
|
[BP] GO:0006939 |
None
|
HTR1D, HTR2A, HTR2B, HTR7 |
2.3344 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.29694 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, MMP12, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
2.26586 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.25228 |
|
[BP] GO:0070302 |
regulation of stress-activated protein kinase signaling cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.2406 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.23111 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, KDR, KIT, TEK |
2.20545 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.20545 |
|
[BP] GO:0010676 |
None
|
INSR, PPARA, PTAFR, SRC |
2.20545 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.20545 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.20545 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.20545 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.20545 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.20545 |
|
[BP] GO:0042307 |
positive regulation of protein import into nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3 |
2.1889 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGS2, SRC |
2.18146 |
|
[BP] GO:0098900 |
None
|
CACNA1C, CNR1, CNR2, GPR35 |
2.17939 |
|
[BP] GO:0007632 |
None
|
APP, DRD3, HMGCR, KIT |
2.17939 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.17644 |
|
[BP] GO:1901184 |
None
|
ADORA1, APP, EGFR, ERBB2, MMP9 |
2.17196 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AR, AXL, BCL2, CA2, CA9, CACNA1C, CYP1B1, EGFR, ESR1, HTR2B, INSR, MET, MMP2, POLB, SMAD3, SRC, TEK |
2.16873 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APP, AURKB, BCL2, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3 |
2.15742 |
|
[BP] GO:1904591 |
positive regulation of protein import
|
APP, EGFR, PRKCD, PTGS2, SMAD3 |
2.15521 |
|
[BP] GO:0000904 |
cell morphogenesis involved in differentiation
|
AR, AXL, MET, SRC, TEK |
2.15521 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.15515 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
ADRB1, BCL2, HTR1A, HTR2C |
2.15515 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.15515 |
|
[BP] GO:0031334 |
positive regulation of protein complex assembly
|
ALOX15, ESR1, HSPA1A, MET, MMP1, MMP3, SRC |
2.15034 |
|
[BP] GO:0031623 |
None
|
ACHE, DRD3, HTR1B, HTR2B |
2.12706 |
|
[BP] GO:0032922 |
None
|
DRD3, PPARA, RORC, TOP1 |
2.12706 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HTR2B |
2.12706 |
|
[BP] GO:0022612 |
gland morphogenesis
|
BCL2, EGFR, POLB |
2.12625 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9 |
2.12625 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2 |
2.12625 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.12302 |
|
[BP] GO:0090257 |
None
|
ADORA1, CACNA1C, CHRM2, KIT, PTAFR, PTGS2, SMAD3 |
2.12096 |
|
[BP] GO:0006935 |
chemotaxis
|
CNR2, KIT, MET, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR |
2.11896 |
|
[BP] GO:0006937 |
None
|
ADORA1, CACNA1C, CHRM2, KIT, PTAFR, PTGS2 |
2.1125 |
|
[BP] GO:0042330 |
taxis
|
CNR2, KIT, MET, MIF, PIK3CA, PIK3CB, PRKCD, PTAFR |
2.11074 |
|
[BP] GO:2000243 |
None
|
AR, INSR, PTAFR, SRC |
2.10389 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9 |
2.10389 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, HMGCR, PTAFR, TYR |
2.10084 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CACNA1C, CSNK2A1, DRD3, EGFR, ERBB2, HMGCR, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.08935 |
|
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP3, MMP9 |
2.08556 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DRD3, DUSP3, FABP4, HMGCR, IGF1R, MMP9, PRKCD, PTGS2, PTPN1, SRC |
2.08073 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.07914 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.07914 |
|
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP3, MMP9 |
2.07914 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.07914 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.07914 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, HSPA1A, MMP1, MMP12, MMP2, MMP3, MMP9, PIK3CB, SRC, XDH |
2.07914 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD3, HTR1B, HTR1E, HTR2A, INSR, PPARA |
2.06499 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
ADRB1, APP, AR, BCL2, DRD3, INSR, PIK3CA, PIM1 |
2.06493 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, HSPA1A, HTR2B, MIF, MMP12, PTAFR, PTGS2, SMAD3, SRC |
2.06411 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
BCL2, CNR1, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCD, PTPN1 |
2.05897 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRB1, CACNA1C, DRD3, EGFR, HTR2B, HTR5A, KDR |
2.05723 |
|
[BP] GO:0050714 |
None
|
ACHE, EGFR, HCAR2, HTR2B, MIF, MMP12, SRC |
2.05723 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.04391 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, CNR1, HCAR2, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC |
2.03292 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.03292 |
|
[BP] GO:0007202 |
None
|
EGFR, HTR2A, HTR2B |
2.03292 |
|
[BP] GO:0032098 |
None
|
HTR2C, HTR4, PPARA |
2.03292 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.03292 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CACNA1C, CNR1, CNR2, GPR35, KDR, SRC |
2.03083 |
|
[BP] GO:0008406 |
gonad development
|
BCL2, CYP19A1, ESR1, INSR, KIT |
2.03067 |
|
[BP] GO:0071502 |
None
|
HTR1B, HTR2B |
2.02684 |
|
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.02684 |
|
[BP] GO:0019229 |
None
|
EGFR, HTR2A, PTAFR, PTGS2 |
2.00975 |
|
[BP] GO:0050866 |
negative regulation of cell activation
|
AXL, CNR1, CNR2, DUSP3, ERBB2, PRKCD |
2.00975 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD3, HTR1B, HTR1E, HTR2A, INSR, PPARA |
2.00113 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, CA4, CHRM2, CNR1, CNR2, DRD3, F10, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, TEK |
7.91034 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, F10, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TEK |
7.60095 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRB1, ALOX15, APP, AXL, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, DRD3, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTGS2, SRC, TEK |
7.46925 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, CHRM2, CNR1, CNR2, DRD3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, TEK |
7.05594 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TEK, TYR |
6.94911 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MPEG1, NR3C2, PIK3CA, PIK3CB, PTAFR, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TYR |
6.94908 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CACNA1C, CBR1, CDC25B, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, INSR, KDR, KIT, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TOP1, TYR, XDH |
3.641 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, F10, FLT3, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1, TBXAS1 |
3.16621 |
|
[CC] GO:0031224 |
None
|
ACHE, ADORA1, ADORA3, ADRB1, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, GPR35, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MPEG1, PTAFR, TBXAS1, TEK, TYR |
3.08475 |
|
[CC] GO:0045121 |
membrane raft
|
APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.89796 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, TBXAS1 |
2.89709 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.87778 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, ERBB2, TEK |
2.58529 |
|
[CC] GO:0016021 |
None
|
ADORA1, ADORA3, ADRB1, ALPL, APP, AXL, CA12, CA14, CA9, CACNA1C, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, FLT3, FUT7, GPR35, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MPEG1, PTAFR, TBXAS1, TEK, TYR |
2.39967 |
|
[CC] GO:0098589 |
membrane region
|
APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.36448 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, ALPL, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, F10, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
17.118 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TYR, XDH |
16.4094 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.8629 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.6196 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.6196 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.6196 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.6196 |
|
[MF] GO:0099528 |
None
|
CHRM2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.0728 |
|
[MF] GO:0008227 |
None
|
ADRB1, CHRM2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5356 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
14.4973 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
12.8591 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, TEK |
12.4413 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, ESR1, F10, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, KIT, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TYR, XDH |
12.3425 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC, SMAD3, TEK |
12.3425 |
|
[MF] GO:0030594 |
None
|
CHRM2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
10.9904 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ERBB2, F10, FLT3, FUT7, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCD, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TOP1, TYR, XDH |
10.2487 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
10.2196 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
10.2196 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
10.1687 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CHRM2, CNR1, CNR2, DRD3, EGFR, ERBB2, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
10.1687 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
10.1325 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.0142 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
9.49797 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, DRD3, EGFR, ERBB2, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCD, SRC, TEK, TOP1 |
9.47817 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC, SMAD3 |
8.93611 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
8.5481 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.22393 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.43407 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR, KIT |
7.11248 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC, TBXAS1 |
6.6573 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.60817 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, F10, KIT, MMP1, MMP12, MMP2, MMP3, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TYR, XDH |
6.45128 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC, TBXAS1 |
6.3754 |
|
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
6.3071 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.27508 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRB1, CHRM2, CNR1, CNR2, DRD3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, PTAFR |
6.22338 |
|
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B2, HSD17B1, NQO2, POLA1, PTGS1, PTGS2, SRC, TBXAS1, XDH |
6.20104 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCD, SRC, TEK, TOP1 |
5.9738 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1, TYR |
5.9509 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, XDH |
5.83012 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
5.75262 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC |
5.72096 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, ADRB1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, XDH |
5.63147 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, NR3C1, NR3C2, PGR, PPARA, RORC |
5.56822 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
5.56696 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, TYR |
5.4157 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.37025 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCD, SRC, TEK, TOP1 |
5.23297 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
5.01895 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.97763 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, ESR1, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, XDH |
4.91735 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.71811 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, HMGCR, HSPA1A, KIT, MET, MIF, NR3C1, PGR, POLA1, POLB, PPARA, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.35944 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
4.02198 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.91995 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.76572 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.75936 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, F10, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, PTAFR, RORC |
3.75774 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, KIT, SMAD3 |
3.61611 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.61142 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, PGR, PPARA, RORC |
3.44882 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, PGR, PPARA, RORC |
3.44882 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.17538 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.06994 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AURKB, AXL, CSNK2A1, EGFR, ERBB2, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TOP1, XDH |
3.05304 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.86832 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.86832 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.86832 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.86832 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
2.83587 |
|
[MF] GO:0000166 |
nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TOP1, XDH |
2.79802 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TOP1, XDH |
2.79693 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, ERBB2, HMGCR, MET, PTPN1 |
2.74459 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, EGFR, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.57612 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.54429 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, EGFR, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.50063 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, APP, AURKB, AXL, CSNK2A1, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, PTAFR, SRC, TEK, TOP1, XDH |
2.4913 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
2.47682 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.46381 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.46381 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP3, MMP9, NUAK1, PIK3CA, PIM1, PRKCD, PTPN1, SRC, TEK, TOP1 |
2.42011 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, APP, BCL2, CSNK2A1, EGFR, ERBB2, ESR1, FLT3, HMGCR, IGF1R, KDR, KIT, MET, MIF, MMP9, NQO2, PGR, PTGS2, SMAD3, TYR, XDH |
2.38156 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
2.36332 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCD, SRC, TEK, TOP1 |
2.3344 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.20545 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, NR3C1, POLA1, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
2.15742 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HSPA1A, KDR, NR3C1 |
2.07644 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, NR3C1, POLA1, PRKCD, PTAFR, PTPN1, SMAD3, SRC |
2.07458 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, NQO2, XDH |
2.03067 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.02684 |
