GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, FABP3, FUT7, GLO1, IDO1, PIM1, PPARA, PTGS2, XDH |
9.55182 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MMP9, PTGS2, SRC, TERT |
8.29098 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, HSD17B1, MET, PPARA, PTGS2 |
7.99527 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9, DHFR |
7.72072 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, FLT3, GSK3B, KDR, MET, MMP12, MMP9, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
7.35643 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, FLT3, GSK3B, KDR, MET, MMP12, MMP9, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
7.35643 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.23977 |
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1, FABP3, FABP4, FLT3, GSK3B, HSD17B1, KDR, MET, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
7.18864 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
7.1868 |
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, APEX1, APP, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MMP2, MMP9, PPARA, PTGS2, SRC, TERT |
7.1868 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP3, GSK3B, IDO1, IGF1R, MMP2, MMP9, PPARA, PTGS2, SRC |
6.9422 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MMP2, PPARA, PTGS2, SRC |
6.81256 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TOP2A, XDH |
6.81256 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
6.80868 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, GSK3B, HSD17B1, IDO1, PTGS2, XDH |
6.75586 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, SRC, TERT, TOP2A, XDH |
6.62941 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
6.6283 |
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
6.44417 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, SRC, TERT |
6.44417 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
6.44417 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP2, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
6.44417 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA2, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP4, FLT3, FUT7, GLO1, GSK3B, KDR, MET, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS2, TOP2A |
6.35755 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
6.20609 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, SRC, TERT |
6.13627 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, SRC, TERT, TOP2A, XDH |
5.99305 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, FABP3, FLT3, GSK3B, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
5.90308 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
5.80714 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, MET, PPARA, PTGS2 |
5.59171 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
5.51723 |
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GLO1, IDO1, PPARA, PTGS2 |
5.50206 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APEX1, APP, CA2, CA9, CSNK2A1, CYP1A2, DRD1, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
5.50206 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, GSK3B, IDO1, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
5.44722 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GLO1, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, SRC, TERT |
5.43827 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, PPARA, PTGS2 |
5.43502 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, APEX1, APP, AXL, CYP1A1, CYP1A2, CYP1B1, DRD1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, PTGS2, SRC, TERT |
5.4205 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
5.33172 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
5.3177 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, KDR, MET, MMP12, MMP9, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
5.3177 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
5.14964 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HSD17B1 |
5.00439 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, GSK3B, IDO1, KDR, MET, MMP12, MMP2, MMP9, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
4.98163 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, DRD1, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MET, MMP12, MMP2, MMP9, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, XDH |
4.96131 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, CYP2D6, GSK3B, MET, MMP9, PPARA, SRC, TERT, TNKS |
4.91809 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, PTGS2, SRC, TERT, TOP2A |
4.90065 |
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT |
4.90065 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.85785 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, CSNK2A1, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, SRC, TERT, XDH |
4.85785 |
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CYP19A1, DHFR, FABP4, GSK3B, IDO1, IGF1R, MET, MMP12, MMP2, PPARA, PTGS2, PTPRS, SRC, TERT, XDH |
4.82899 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, XDH |
4.80037 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, XDH |
4.69382 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
4.66223 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, PIM1, SRC |
4.66223 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, CYP2D6, FABP4, GSK3B, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, SRC, TNKS |
4.65516 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APEX1, APP, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FLT3, PTGS2, SRC |
4.64512 |
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, CA9, CYP1A1, CYP1B1, DHFR, DRD1, FABP3, KDR, PTGS2, SRC |
4.58839 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, GSK3B, MET, MMP9, PPARA, SRC, TERT |
4.54259 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.50542 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.49332 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
4.45708 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, CYP1A1, CYP1B1, DRD1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, PTGS2, SRC |
4.45532 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DHFR, DRD1, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
4.45532 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, APEX1, APP, AURKB, AXL, CSNK2A1, DHFR, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PTGS2, PTPRS, SRC, TNKS, XDH |
4.42985 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, IDO1 |
4.29274 |
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
4.26012 |
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, CA2, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2, TERT |
4.22696 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
4.22567 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
4.14585 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, APEX1, APP, AURKB, AXL, CSNK2A1, DHFR, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PTGS2, PTPRS, SRC, TNKS, XDH |
4.14585 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DHFR, DRD1, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
4.12436 |
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PPARA, PTGS2, SRC, TERT, TOP2A |
4.12436 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, GSK3B, IDO1, MMP2, MMP9, PPARA, PTGS2, SRC, TERT, TOP2A |
4.09855 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GSK3B, IGF1R, PPARA, PTGS2, SRC |
3.9389 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
3.88423 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, DRD1, KDR, PTGS2, SRC, TNKS, TNKS2 |
3.80591 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
3.79401 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AURKB, AXL, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DHFR, DRD1, FLT3, FUT7, GLO1, GSK3B, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TNKS, TNKS2, TOP2A, XDH |
3.75276 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CYP1B1, DRD1, GSK3B, IGF1R, MMP2, MMP9, PTGS2, SRC |
3.70757 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, PTGS2 |
3.63028 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, DRD1, KDR, PTGS2, SRC |
3.63028 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, GSK3B, IGF1R, MMP2, PTGS2, SRC |
3.54493 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CSNK2A1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC, TNKS |
3.54493 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, IDO1 |
3.53732 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, APEX1, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, PPARA, PTGS2, SRC |
3.44966 |
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, CA2, CYP19A1, DRD1, GSK3B, MMP12, PTGS2, SRC, TERT |
3.4203 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1 |
3.39435 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2, TERT |
3.34426 |
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
3.33643 |
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7 |
3.31922 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.31922 |
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, GSK3B, IGF1R, MMP2, PTGS2, SRC |
3.29583 |
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, PTGS2, TNKS, TNKS2 |
3.23669 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, CA12, CA2, CA7, DRD1, FABP3, FABP4, FLT3, MET, SRC, TERT |
3.22535 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
3.19699 |
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
3.18785 |
[BP] GO:0033993 |
response to lipid
|
AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, IDO1, PTGS2, SRC |
3.12453 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, CSNK2A1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, SRC, TNKS, TOP2A |
3.10025 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
3.09005 |
[BP] GO:0051100 |
negative regulation of binding
|
AURKB, CYP2D6, GSK3B, MET, PPARA, TNKS |
3.09005 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, CYP1B1, MMP9, PTGS2, SRC |
3.08418 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APEX1, APP, CYP1A1, CYP1B1, DRD1, FLT3, PTGS2, SRC |
3.01419 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
3.00558 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AXL, CYP19A1, CYP1A2, CYP1B1, DRD1, FABP4, IDO1, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TNKS2 |
2.99597 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, FLT3, GSK3B, KDR, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC |
2.97296 |
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, CA2, CA7, CYP19A1, DRD1, GSK3B, MMP12, MMP9, PPARA, PTGS2, SRC, TERT |
2.91737 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
2.90811 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, DRD1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
2.90516 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.86786 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.84239 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, FABP4, IDO1, KDR, MET, MMP12, PPARA, PTGS2, PTPRS |
2.83912 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
2.83912 |
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.83912 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, CSNK2A1, DHFR, DRD1, FABP3, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.83912 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, CYP19A1, DRD1, GSK3B, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPRS, SRC, TERT, XDH |
2.83912 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.81927 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, CYP1A1, DHFR, PPARA |
2.79425 |
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.76539 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, XDH |
2.7521 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
2.74662 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1 |
2.73862 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, SRC |
2.73862 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1 |
2.73862 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, CYP1B1, FLT3, KDR, MET, PTGS2, SRC, XDH |
2.73684 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.7351 |
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AURKB, CSNK2A1, CYP1B1, CYP2D6, DHFR, DRD1, FABP4, FLT3, GSK3B, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TNKS, XDH |
2.7351 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, CSNK2A1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC, TNKS |
2.7351 |
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.71972 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.70657 |
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.70487 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, APP, AXL, CBR1, CYP1A1, DRD1, FABP4, FLT3, FUT7, GLO1, GSK3B, KDR, MET, MMP2, MMP9, PTGS2, PTPRS, SRC, TERT, TOP2A |
2.70487 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1A1, CYP1B1, DRD1, KDR, SRC |
2.69905 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, GSK3B, IGF1R, KDR, MET, MMP1, MMP9, SRC, TNKS, TNKS2 |
2.67994 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, GSK3B, IDO1, XDH |
2.67994 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
2.67994 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.66647 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, CA2, CYP1A1, DRD1, MMP2, PPARA, PTGS2, SRC, TERT |
2.65951 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DRD1, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC |
2.6577 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, CSNK2A1, CYP2D6, DHFR, FABP4, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
2.61593 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, CSNK2A1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.60602 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, PTGS2 |
2.60602 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, PTGS2 |
2.60602 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.57828 |
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, TERT, TNKS, TNKS2 |
2.56218 |
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6 |
2.56218 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.5537 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.5537 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.55014 |
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.54603 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC |
2.54603 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, PTGS2, SRC, XDH |
2.54393 |
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GSK3B, IGF1R, SRC |
2.54262 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, CA2, CA7, DRD1, KDR, SRC |
2.54262 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.52972 |
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, XDH |
2.52972 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
2.52865 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.52865 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.51972 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.51972 |
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, DHFR, IDO1, PTGS2 |
2.5036 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TERT |
2.50116 |
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2, TERT |
2.49264 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, FABP3, KDR, MMP2, PTGS2, SRC |
2.47473 |
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, PTGS2 |
2.47473 |
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.47473 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.47473 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.4506 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, DRD1, FABP3, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.42388 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.42139 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, CSNK2A1, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.3934 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, GLO1, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.38635 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1 |
2.37488 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.37488 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, DRD1, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPRS, SRC, TERT, XDH |
2.37116 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, DRD1, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPRS, SRC, TERT, XDH |
2.35923 |
[BP] GO:1901992 |
positive regulation of mitotic cell cycle phase transition
|
APEX1, APP, CYP1A1, TERT |
2.34458 |
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.32897 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.32897 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.32897 |
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, GSK3B, KDR, MET, MMP9, SRC, TNKS, TNKS2 |
2.31604 |
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.28502 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.28502 |
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, CA2, CA9, CYP1B1, DHFR, GSK3B, MMP9, PTGS2, SRC, TERT, TOP2A |
2.24596 |
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, FABP4, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPRS, SRC |
2.24596 |
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.24596 |
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.24596 |
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, CSNK2A1, CYP2D6, DHFR, FABP4, GSK3B, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, XDH |
2.23497 |
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, CA9, CSNK2A1, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, GLO1, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.23497 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, GSK3B, IDO1, SRC, XDH |
2.2263 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, PPARA, PTGS2, SRC |
2.20504 |
[BP] GO:0032204 |
None
|
AURKB, SRC, TNKS, TNKS2 |
2.19364 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, SRC |
2.1832 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.17578 |
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DHFR, GSK3B, IGF1R, MET, PTGS2, PTPRS, TERT, XDH |
2.16747 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.13708 |
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.12723 |
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7 |
2.12 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, PTGS2 |
2.10131 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, KDR, PPARA, PTPRS, SRC |
2.09474 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.08789 |
[BP] GO:1901989 |
None
|
APEX1, APP, CYP1A1, TERT |
2.08655 |
[BP] GO:0051099 |
positive regulation of binding
|
APP, GSK3B, MET, MMP9, TERT |
2.07894 |
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, DRD1, FABP3, IGF1R, KDR, MET, MMP12, PPARA, PTGS2, SRC, TERT, TNKS, TNKS2, TOP2A |
2.07772 |
[BP] GO:0032092 |
positive regulation of protein binding
|
APP, GSK3B, MMP9, TERT |
2.07197 |
[BP] GO:0046394 |
None
|
ALOX15, ALOX5, CYP1A1, DHFR, IDO1, PTGS2 |
2.06567 |
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, DRD1, GSK3B, SRC, TNKS |
2.06567 |
[BP] GO:0030177 |
positive regulation of Wnt signaling pathway
|
CSNK2A1, SRC, TERT, TNKS, TNKS2 |
2.06567 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.06567 |
[BP] GO:0016053 |
None
|
ALOX15, ALOX5, CYP1A1, DHFR, IDO1, PTGS2 |
2.06467 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.06467 |
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.0483 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, CSNK2A1, DHFR, DRD1, FABP4, FLT3, GSK3B, IGF1R, MMP9, PTGS2, SRC, TERT, TNKS, XDH |
2.00561 |
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX15, ALOX5 |
2.00561 |
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6 |
2.00561 |
[BP] GO:0032212 |
positive regulation of telomere maintenance via telomerase
|
AURKB, TNKS, TNKS2 |
2.00513 |
[BP] GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, MMP9, PTGS2, SRC |
2.00513 |
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, APEX1, APP, AURKB, AXL, CA1, CA2, CA4, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, XDH |
2.76401 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, CA1, CA2, CA4, CA7, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, KDR, MMP2, MMP9, PIM1, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, XDH |
2.67994 |
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, APEX1, APP, AURKB, AXL, CA1, CA2, CA4, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, XDH |
2.51957 |
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APP, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, FLT3, GLO1, GSK3B, IGF1R, KDR, MET, MMP2, PIM1, PTPRS, SRC, TERT |
1.95859 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.806 |
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, FLT3, FUT7, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, XDH |
13.8536 |
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FABP3, FABP4, FLT3, GLO1, GSK3B, HSD17B1, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, XDH |
13.463 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, GLO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, TNKS, XDH |
10.8111 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.5133 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.23977 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, HSD17B1, IDO1, PTGS2, XDH |
6.95665 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.77168 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, TERT, TNKS, TNKS2, TOP2A, XDH |
6.4212 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
5.90312 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, IDO1, PTGS2, SRC |
5.83767 |
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PPARA, SRC, TOP2A |
5.83464 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, IDO1, PTGS2, SRC |
5.61315 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
5.60382 |
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, TERT, TNKS, TNKS2, TOP2A, XDH |
5.43502 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
5.41237 |
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, XDH |
5.24832 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, HSD17B1, IDO1, PTGS2, SRC, XDH |
4.62476 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
4.36505 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, GLO1, MMP1, MMP12, MMP2, MMP9, PPARA, TNKS |
4.16908 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.75276 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.74037 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.69739 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.28035 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS2 |
3.09005 |
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, APP, AURKB, AXL, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IGF1R, KDR, MET, PIM1, PTPRS, SRC, TOP2A, TUBB3, XDH |
2.98172 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
2.94247 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.76981 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.76235 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.73862 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PPARA, SRC |
2.70502 |
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AURKB, AXL, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IGF1R, KDR, MET, PIM1, SRC, TOP2A, TUBB3, XDH |
2.65203 |
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.5537 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, XDH |
2.38635 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.25519 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, FLT3, IGF1R, KDR, MMP12, MMP9, PPARA, SRC |
2.22753 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC, TERT |
2.06878 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.00561 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.00513 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2D6 |
2.00513 |
[MF] GO:0051213 |
dioxygenase activity
|
ALOX15, ALOX5, IDO1, PTGS2 |
2.00513 |