| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCHE, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HIF1A, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MAOA, MET, MIF, MTNR1B, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGS1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
14.9247 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, FABP3, FABP4, FUCA1, FUT7, GBA, HSD17B1, HSD17B2, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TRPV1 |
12.5328 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCHE, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP3, GBA, GRIK5, GRM5, HSD17B2, IGF1R, INSR, MMP2, MMP9, PIK3CA, POLB, PPARA, PTGES, PTGS2, SRC, TEK, TRPV1, TYR |
11.8795 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCHE, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, PIK3CA, POLB, PPARA, PTGES, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
11.6452 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
11.2369 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES, PTGS1, PTGS2, TBXAS1 |
11.2059 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
10.9896 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCHE, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, POLB, PPARA, PTGES, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
10.9896 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, FUCA1, FUT7, GAA, GBA, GLO1, HIF1A, HSPA1A, MIF, PIK3CA, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.9896 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.2155 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.0369 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, FLT3, GBA, GPR35, GRM1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.0369 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, INSR, MET, MTNR1B, PIK3CA, PIK3CB, POLA1, POLB, SMAD3, SRC, TERT, TRPV1 |
10.0367 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, FLT3, GBA, GPR35, GRM1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.0367 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, BCHE, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DNMT1, EGFR, ESR1, FABP3, FLT3, HIF1A, HSPA1A, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
9.42796 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GBA, GLO1, GRIK5, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.41357 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, PTGS2, SMAD3, SRC, TERT, TRPV1 |
9.0959 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
8.99287 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MIF, MMP2, MMP9, NUAK1, PIK3CA, POLA1, POLB, PTGS2, PTPN1, SMAD3, SRC, TERT, TOP2A, TRPV1 |
8.9243 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, FABP3, FABP4, FUCA1, FUT7, GBA, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
8.9164 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GRIK5, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
8.89962 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, HIF1A, KDR, MMP9, PTGES, PTGS2, SRC, TERT |
8.85894 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, BCHE, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, EGFR, ESR1, FABP3, FLT3, GBA, GRM5, IGF1R, INSR, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TRPV1 |
8.77599 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP2, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
8.66556 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
8.66556 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES, PTGS1, PTGS2, TBXAS1 |
8.64145 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.56181 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GRIK5, HIF1A, HSPA1A, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
8.36002 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, IGF1R, INSR, KDR, MMP2, PIK3CA, PTGS2, SMAD3, SRC, TRPV1 |
8.35186 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GBA, GLO1, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.35186 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, FLT3, GPR35, GRM1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.33222 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
7.83736 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, GBA, GPR35, GRM1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.73397 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, IGF1R, INSR, KDR, MIF, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.57546 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.57546 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.57546 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.54052 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, IGF1R, INSR, KDR, MIF, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.52535 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCHE, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FLT3, GBA, PTGES, PTGS2, SRC, TEK, TRPV1, TYR |
7.4325 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, GAA, HSD17B1, HSD17B2, MAOA, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
7.37134 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCHE, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, FABP3, FLT3, GBA, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
7.33538 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, INSR, KDR, MIF, MMP9, MTNR1A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.15499 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, INSR, KDR, MIF, MMP9, MTNR1A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.15499 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.1154 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HSPA1A, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.00061 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, INSR, MET, MTNR1B, PIK3CA, PIK3CB, SMAD3, TRPV1 |
6.97828 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, HIF1A, MIF, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
6.9545 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCHE, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, HIF1A, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
6.84795 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, BCHE, CA2, CA7, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.84795 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, BCHE, CA2, CA7, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.84795 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCHE, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, FABP3, FLT3, GBA, HSD17B2, PTGES, PTGS2, SRC, TYR |
6.75035 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CDK6, CYP19A1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, GBA, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
6.75035 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, EGFR, FLT3, GPR35, GRM1, HSPA1A, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.75035 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, EGFR, GPR35, GRIK5, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
6.73204 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
6.72862 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.57768 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCHE, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, FLT3, FUT7, GAA, GBA, GLO1, HIF1A, HSD17B2, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
6.52753 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
6.46072 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGES, PTGS1, PTGS2, TBXAS1 |
6.35863 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.29577 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, EGFR, HIF1A, KDR, MIF, PIK3CB, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
6.19737 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.15988 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.1015 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.10099 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.07743 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DYRK1A, EGFR, ESR1, FLT3, GBA, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.07743 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.0617 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
6.04677 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.04677 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, FABP4, FLT3, GPR35, GRM1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
6.04209 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.9232 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, EGFR, GBA, GRM1, HIF1A, HSPA1A, MMP2, POLB, PPARA, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
5.91858 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, BCHE, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PPARA, PTGES, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.87052 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CDK6, CYP1B1, DNMT1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PTGS2, SRC, TRPV1 |
5.78892 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, HIF1A, MMP9, PTGES, PTGS2, TERT |
5.71097 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, DNMT1, DYRK1A, EGFR, ESR1, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.69053 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, HIF1A, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
5.64872 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AXL, BCHE, BCL2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, FABP4, GAA, GBA, GRM1, GRM5, GRM8, HIF1A, HSD17B2, IGF1R, INSR, MET, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PTGS2, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
5.57558 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, GBA, GPR35, GRM1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
5.54377 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, HIF1A, HSPA1A, IGF1R, INSR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.52627 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, BCL2, CDK6, CYP19A1, DUSP3, DYRK1A, EGFR, ESR1, GBA, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
5.46582 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, ESR1, FLT3, HIF1A, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK, TERT |
5.45925 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCHE, BCL2, DUSP3, DYRK1A, EGFR, ESR1, GBA, GPR35, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.41278 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
5.39696 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCHE, BCL2, DUSP3, DYRK1A, EGFR, ESR1, GBA, GPR35, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.39527 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, FLT3, GRM1, GRM5, HIF1A, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.39259 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, FLT3, HIF1A, HSD17B2, INSR, KDR, PIK3CA, POLB, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
5.39259 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HIF1A, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
5.39259 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DYRK1A, EGFR, ESR1, FLT3, GBA, GRM1, GRM5, HSPA1A, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.37607 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CYP19A1, EGFR, GPR35, GRIK5, GRM5, HIF1A, HSPA1A, INSR, MIF, MMP12, MMP9, MTNR1B, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
5.34176 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.30667 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
5.28131 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HIF1A, MMP2, POLB, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
5.28131 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, BCHE, BCL2, CA9, CDK6, CYP1A1, CYP1B1, EGFR, FABP3, GBA, KDR, POLB, PTGS2, SRC, TRPV1 |
5.28131 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DYRK1A, EGFR, FLT3, GBA, GRM1, GRM5, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.28131 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DYRK1A, EGFR, ESR1, FLT3, GBA, GRM1, GRM5, HSPA1A, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.27415 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
5.26183 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DUSP3, DYRK1A, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.22613 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DYRK1A, EGFR, ESR1, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.22613 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, FLT3, GBA, GPR35, GRM1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
5.22465 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.19681 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
5.14201 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.14139 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, BCHE, DNMT1, EGFR, FABP3, FLT3, GRM5, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
5.10433 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCHE, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PPARA, PTGES, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.10181 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, FABP4, FLT3, GBA, GPR35, GRM1, GRM3, GRM5, HIF1A, HSPA1A, IGF1R, INSR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
5.09958 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, FLT3, GRM1, GRM5, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.09362 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, GBA, HIF1A, HSPA1A, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
5.09362 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.09362 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, DYRK1A, ESR1, GBA, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP9, PTGS2, PTPN1, SRC, XDH |
5.09362 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, HSD17B1, HSD17B2 |
5.09362 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, HIF1A, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
5.09124 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.03955 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, HIF1A, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.97164 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, BCHE, CYP1B1, EGFR, GRIK5, INSR, MAOA, PTGS2, SLC1A1, SMAD3, TRPV1 |
4.97081 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, HSPA1A, MAOA, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
4.97081 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
4.9617 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.93551 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
4.93551 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, GBA, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.92837 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HIF1A, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
4.91782 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
4.798 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HIF1A, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
4.79287 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DUSP3, EGFR, FLT3, GBA, GRM1, IGF1R, INSR, KDR, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
4.78298 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, GBA, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
4.76272 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5 |
4.74305 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, BCHE, DNMT1, EGFR, FABP3, FLT3, GRM5, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
4.68703 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, IGF1R, INSR, MIF, PIK3CB, PTPN1, SRC |
4.67712 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
4.67535 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DYRK1A, EGFR, ESR1, FLT3, GBA, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.65339 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HIF1A, HSPA1A, IGF1R, MET, MIF, NUAK1, PTGS2, PTPN1, PTPRS, TERT, XDH |
4.65339 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS1, PTGS2, SRC |
4.64888 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, EGFR, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
4.64888 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DAO, GBA, HIF1A, MAOA, TYR |
4.64065 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, MIF, PIK3CB, PIM1, POLA1, SRC, TEK, TYR |
4.62169 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, HIF1A, INSR, PTGS2, SMAD3, TRPV1, XDH |
4.59497 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.58929 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, IGF1R, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
4.58929 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DYRK1A, EGFR, ESR1, MTNR1A, MTNR1B, PPARA, SRC, TOP2A |
4.58263 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.55709 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.51802 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, APP, AURKB, AXL, BACE1, BCHE, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, DAO, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUCA1, FUT7, GBA, GLO1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
4.49748 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
4.48827 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, EGFR, FLT3, GRM1, INSR, KDR, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
4.44702 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
4.40278 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, DNMT1, ESR1, GBA, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.38098 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, FLT3, GRM1, GRM5, HIF1A, HSPA1A, INSR, MET, MIF, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.34188 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, ESR1, GAA, GPR35, GRIK5, GRM1, GRM5, HIF1A, PIK3CA, PIK3CB, POLA1, SMAD3, TRPV1 |
4.30706 |
|
[BP] GO:0001516 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.29803 |
|
[BP] GO:0046457 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.29803 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
4.29105 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.23316 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, FLT3, GRM1, GRM5, HIF1A, HSPA1A, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.22345 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.16284 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, BCHE, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, PTGS2, SRC |
4.08669 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, EGFR, GRM5, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
4.06812 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.01454 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DNMT1, EGFR, ESR1, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PTGES, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
3.9972 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AXL, BCL2, CA2, CDK6, CYP1B1, EGFR, ESR1, GAA, GBA, GPR35, GRM1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PTGS2, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
3.9924 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.99141 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
3.94115 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCHE, BCL2, EGFR, FLT3, GBA, PTGS2, SRC |
3.88772 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
3.87753 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
3.87753 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.87753 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.87753 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA, SLC1A1, TRPV1 |
3.85331 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
3.85331 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
3.8525 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GBA, GPR35, GRM3, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
3.8525 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, GBA, GRM3, GRM8, HIF1A, HSPA1A, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.8489 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.84757 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUCA1, FUT7, GAA, HSPA1A, MGAM, MIF, MMP9, PIK3CA, PIK3CB, SMAD3, SRC, TRPV1 |
3.84427 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
3.82544 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, EGFR, HIF1A, INSR, MIF, MMP12, PTGS2, SMAD3, SRC, TERT, TRPV1 |
3.82258 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTGS2, SRC, TRPV1 |
3.78422 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, GAA, HIF1A, HSD17B2, INSR, KDR, MMP9, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPRS, SMAD3, SRC, TEK, TYR |
3.78365 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KDR, PTGS2, SRC, TRPV1 |
3.78296 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCHE, BCL2, CA2, EGFR, FLT3, GBA, PTGS2, SRC |
3.77736 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, EGFR, GRM5, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
3.77399 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DUSP3, DYRK1A, EGFR, ESR1, GBA, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
3.77393 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DNMT1, EGFR, ESR1, FLT3, GRM5, IGF1R, INSR, MMP2, PTGS2, SMAD3, SRC, TRPV1 |
3.77229 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, GBA, HIF1A, HSPA1A, MIF, MMP9, NUAK1, POLA1, POLB, PTGS2, PTPN1, SRC, TERT, TOP2A, TRPV1 |
3.77229 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, FUCA1, GBA |
3.76729 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
3.76442 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.76442 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
BCHE, CYP1A1, CYP1A2, CYP1B1, CYP2A13, NQO2, PTGS1 |
3.76442 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.73943 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.73943 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, MIF, PIK3CA, PIK3CB, POLB, PTGES, PTGS1, PTGS2, TRPV1 |
3.71978 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GBA, HSPA1A, MMP12, MMP2, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
3.70782 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, EGFR, HIF1A, PIK3CB, PTGS2, TNKS, TNKS2 |
3.68915 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTGS2, TERT |
3.66235 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.63069 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, BCHE, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, EGFR, HSPA1A, MAOA |
3.62351 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, INSR, MIF, SRC, TERT |
3.59311 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.58488 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
3.542 |
|
[BP] GO:0007610 |
None
|
APP, BCHE, BCL2, EGFR, GAA, GRM1, GRM5, HIF1A, INSR, MTNR1A, PPARA, PTGS2, TRPV1 |
3.52568 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PTGS2, SRC, TEK |
3.52386 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, PPARA, SMAD3 |
3.50399 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, MIF |
3.48959 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, BCHE, CYP1A1, EGFR, PTGS2, TYR |
3.48959 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.47084 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.46827 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, BCHE, CSNK2A1, DAO, GBA, MAOA |
3.45909 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.43174 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.43174 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
3.42952 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.41334 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CSNK2A1, DNMT1, DUSP3, DYRK1A, ESR1, FABP4, GBA, GRM3, GRM8, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.39973 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.36986 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.36843 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPR35, GRIK5, GRM1, GRM5, HIF1A, PIK3CA, PIK3CB, SMAD3, TRPV1 |
3.35674 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, FLT3, GBA, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.30942 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.3032 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1, XDH |
3.28216 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.2804 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.2804 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCHE, BCL2, EGFR, FLT3, GBA, PTGS2 |
3.2587 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AXL, BCL2, CA2, CYP1B1, EGFR, GBA, HIF1A, HSPA1A, KDR, MET, MIF, MMP12, MMP9, PIM1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
3.25294 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, MIF, PIK3CB, PTPN1, SRC |
3.20287 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.17422 |
|
[BP] GO:0006693 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.17422 |
|
[BP] GO:0006692 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.17422 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, TERT |
3.17045 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, MIF, SRC, TNKS, TNKS2, TRPV1 |
3.17045 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.15921 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, IGF1R, INSR, MIF, PIK3CB, PTPN1, SRC |
3.1539 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GBA, KDR, MET, MIF, MMP12, PPARA, PTGS2, PTPRS, SMAD3, TEK |
3.14232 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.14232 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, FUCA1, GBA |
3.14003 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
3.13785 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
3.13219 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.1246 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, HIF1A, HSD17B1, HSD17B2, MTNR1B |
3.11441 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.11291 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.11167 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DUSP3, EGFR, KDR, MIF, PTPN1, SRC, TEK |
3.10242 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
3.08296 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
3.08084 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.07742 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, DNMT1, EGFR, ESR1, GBA, GRIK5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.06715 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCHE, BCL2, CYP1A1, EGFR, GBA, PTGS2, SRC, TRPV1, TYR |
3.057 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
3.05262 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, BCHE, BCL2, CDK6, CYP1B1, FABP3, HSPA1A, PTGES, PTGS2, SMAD3, TERT, XDH |
3.05118 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
3.03335 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
3.0201 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, GBA, HIF1A, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1, SMAD3 |
2.99495 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.98006 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, EGFR, HSPA1A, INSR, MIF, TERT, TNKS |
2.95343 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.95324 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.93714 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
2.91867 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.89357 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.86783 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA, SLC1A1, TRPV1 |
2.85821 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CYP19A1, DUSP3, ESR1, HIF1A, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, PTPRS, SMAD3, SRC |
2.8132 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, HIF1A, KDR, POLB, TEK, TYR |
2.81121 |
|
[BP] GO:1902893 |
None
|
HIF1A, PPARA, SMAD3, TERT |
2.81121 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, MIF, PTPN1, SRC |
2.80708 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CYP1A1, MIF, POLB, PTGS2, TERT |
2.80708 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.79848 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.77437 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, GBA, PPARA, SMAD3, TEK |
2.76353 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.76353 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, GBA, MMP12, PPARA, SMAD3, TEK |
2.76259 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.74763 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GBA, PPARA, PTGS2, SMAD3, TEK |
2.74559 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, HSPA1A, MAOA, MGAM, XDH |
2.72961 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
2.7201 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, GBA, MET, PIK3CA, TRPV1 |
2.71105 |
|
[BP] GO:0034097 |
response to cytokine
|
ALOX15, AXL, BCL2, FABP4, FLT3, GBA, HIF1A, PTGES, PTGS2, SRC, TRPV1 |
2.70978 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.68889 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.6877 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
2.67511 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, GBA, GRIK5, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.66835 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.65946 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, EGFR, PTGS2 |
2.65835 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
2.65197 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, KDR, POLB, SRC |
2.63538 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
2.63336 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
2.62569 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCHE, BCL2, CYP1A1, EGFR, GBA, PTGS2, SRC, TRPV1, TYR |
2.61184 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AXL, BCHE, BCL2, CBR1, CDC25B, CDK6, CYP1A1, EGFR, ESR1, FABP4, FLT3, FUT7, GLO1, HIF1A, KDR, MET, MIF, MMP2, MMP9, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, TOP2A |
2.61117 |
|
[BP] GO:0007187 |
None
|
ADORA1, GRM1, GRM3, GRM5, GRM8, MTNR1A, MTNR1B |
2.60318 |
|
[BP] GO:0007193 |
None
|
ADORA1, GRM1, GRM3, GRM5, GRM8 |
2.59126 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.57109 |
|
[BP] GO:1901215 |
negative regulation of neuron death
|
AXL, BCL2, GBA, HIF1A, PIK3CA, PPARA, TERT |
2.56192 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, EGFR, ESR1, HIF1A, HSD17B2, INSR, MMP2, MMP9, MTNR1A, PTGS2, SRC, TOP2A |
2.55605 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, FLT3, GBA, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.55195 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DAO, MAOA, TYR |
2.54522 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, HIF1A, KDR, MMP2, PIK3CA, PIK3CB, PTGS2, TEK |
2.54423 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTGS2, TERT |
2.54423 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, GBA, GRM3, GRM8, HSPA1A, IGF1R, MIF, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.52709 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, HIF1A, HSD17B2, INSR, PTGS2, SRC |
2.51887 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
2.51614 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, FLT3, GBA, GLO1, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.51614 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PTGS2, SMAD3, SRC, TERT |
2.51476 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.51476 |
|
[BP] GO:0009268 |
None
|
CA2, GBA, SRC, TRPV1 |
2.49869 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.49848 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.49703 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUT7, HIF1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.49357 |
|
[BP] GO:0032963 |
collagen metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.48378 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, BCHE, CYP1A1, EGFR, PTGS2, TRPV1, TYR |
2.48378 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
2.48049 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HIF1A, MIF, PIK3CB |
2.46391 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.46391 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCHE, BCL2, CYP1B1, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, INSR, PIK3CA, PTGS2, SRC, TEK, TRPV1, TYR |
2.45724 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, EGFR, GAA, GBA, GPR35, GRM1, PTGS2, SLC1A1, SMAD3, TRPV1 |
2.44101 |
|
[BP] GO:0060249 |
None
|
AKR1B1, APEX1, BCL2, GAA, HIF1A, POLA1, SRC, TERT |
2.44101 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, EGFR, KDR, MIF, SRC, TEK |
2.43774 |
|
[BP] GO:0001961 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.43434 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.43434 |
|
[BP] GO:0007612 |
None
|
APP, BCHE, GRM5, HIF1A, INSR, PTGS2 |
2.43308 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.43308 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.43308 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.43308 |
|
[BP] GO:0048546 |
None
|
BCL2, EGFR, HIF1A |
2.43308 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.43308 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.43035 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
HIF1A, KDR, MET, PTGS2, TEK |
2.41008 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, BCHE, EGFR, GRM5, HIF1A, INSR, PTGS2 |
2.40331 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, MIF, PIK3CB, PTPN1, SRC |
2.40084 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.40059 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.40059 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.40059 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.40059 |
|
[BP] GO:0006633 |
None
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
2.40059 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.40059 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, GBA, MIF, PTGES, PTGS1, PTGS2 |
2.39186 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, FABP3, FABP4, FUCA1, GAA, GBA, HSPA1A, MAOA, MGAM, PIK3CB, SRC, XDH |
2.39186 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.388 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.38004 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, EGFR, FUT7, HIF1A, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.37676 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.37676 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
2.35926 |
|
[BP] GO:1901214 |
regulation of neuron death
|
AXL, BCL2, GBA, GRIK5, HIF1A, PIK3CA, PPARA, TERT |
2.35926 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.35632 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.35437 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, EGFR, ESR1, FABP3, GBA, HIF1A, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, PPARA, PTGS2, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.35322 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, GBA, MIF, PPARA, PTPRS, SMAD3, TEK |
2.35248 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, SRC |
2.33624 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, KDR, SRC, TRPV1 |
2.33624 |
|
[BP] GO:2000107 |
negative regulation of leukocyte apoptotic process
|
AURKB, AXL, HIF1A, MIF |
2.32744 |
|
[BP] GO:0060760 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.32744 |
|
[BP] GO:0016311 |
None
|
ALPL, APEX1, BCL2, CDC25B, DUSP3, POLB, PTPN1, PTPRS |
2.30499 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
2.3046 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.30353 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, ESR1, GAA, GBA, HIF1A, INSR, MET, MMP2, POLB, SMAD3, SRC, TEK |
2.27801 |
|
[BP] GO:0072330 |
monocarboxylic acid biosynthetic process
|
ALOX15, CYP1A1, MIF, PTGES, PTGS1, PTGS2 |
2.27493 |
|
[BP] GO:0035239 |
tube morphogenesis
|
BCL2, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.25755 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PTGS2, SRC, TEK |
2.25755 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.25005 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, BCL2, CSNK2A1, EGFR, HIF1A, HSPA1A, INSR, PIK3CA, PIM1, PTPRS, SMAD3, TNKS2 |
2.24845 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUT7, HIF1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.23657 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, GBA, GRIA2, GRIK5, GRM1, GRM3, GRM5, MTNR1B, PTGS2, SLC1A1, TEK, TRPV1 |
2.22326 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, HIF1A, KDR, PTGS2, TEK, TERT |
2.19471 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
2.18414 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, EGFR, HIF1A, MIF, MMP12, SRC, TRPV1 |
2.17653 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUT7, HIF1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.17335 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUT7, HIF1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.17335 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, FLT3, FUT7, HIF1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.17335 |
|
[BP] GO:0048146 |
positive regulation of fibroblast proliferation
|
CDK6, EGFR, ESR1, MIF |
2.15361 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.15361 |
|
[BP] GO:0098908 |
None
|
GBA, GPR35 |
2.15361 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.15361 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.15361 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.13839 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PIK3CA, SRC, TNKS, TNKS2 |
2.1379 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.12981 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.12981 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.12981 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.12981 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.12981 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.12981 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, BCHE, CYP1B1, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, INSR, PTGS2, TRPV1, TYR |
2.12616 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.11243 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP4, GBA, HIF1A, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.10947 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
2.10813 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
2.10322 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, DAO, GBA, TYR |
2.10322 |
|
[BP] GO:0090344 |
None
|
CDK6, MIF, TERT |
2.0945 |
|
[BP] GO:0022612 |
gland morphogenesis
|
BCL2, EGFR, POLB |
2.0945 |
|
[BP] GO:1902895 |
None
|
HIF1A, SMAD3, TERT |
2.0945 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.0945 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, MMP9, TERT |
2.08501 |
|
[BP] GO:0071456 |
cellular response to hypoxia
|
BCL2, HIF1A, PTGS2, SRC, TERT |
2.08442 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
2.07782 |
|
[BP] GO:0007611 |
None
|
APP, BCHE, EGFR, GRM5, HIF1A, INSR, PTGS2 |
2.06986 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
2.06619 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.06171 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, EGFR, FUT7, HIF1A, KDR, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.06171 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, SMAD3, TEK |
2.05266 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.04743 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.04743 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.03735 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.03704 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, EGFR, FUT7, HIF1A, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.02741 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DNMT1, EGFR, GRM5, IGF1R, INSR, KDR, MET, MIF, NUAK1, PIK3CA, PIK3CB, POLB, PTPN1, SRC, TEK |
2.02741 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CYP19A1, DUSP3, MIF, MMP12, PTPRS |
2.0249 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, EGFR, HIF1A, MIF, MMP12, MTNR1B, PTGS2, PTPN1, SMAD3, SRC |
2.00126 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.00121 |
|
[BP] GO:0061900 |
None
|
APP, EGFR, TRPV1 |
2.00121 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.00121 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, APP, AXL, BACE1, BCHE, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, EGFR, ESR1, FLT3, FUT7, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD17B2, IGF1R, INSR, KDR, MAOA, MET, MGAM, MMP2, MTNR1A, MTNR1B, PIK3CA, PIK3CB, PIM1, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
5.83814 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, CA2, CA4, CA9, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, MGAM, PTGS2, SLC1A1, SRC, TEK, TRPV1 |
5.4576 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CSNK2A1, EGFR, ESR1, FLT3, GAA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MGAM, MMP2, MTNR1A, MTNR1B, PIK3CA, PIK3CB, PIM1, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
5.14139 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, BCHE, PTGES |
5.13647 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, DUSP3, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MGAM, MTNR1A, MTNR1B, PTGS2, PTPRS, SLC1A1, SRC, TEK, TRPV1 |
4.68703 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, APP, AURKB, BACE1, BCHE, BCL2, CA1, CA2, CA4, CA7, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GRIA2, GRIA4, GRIK5, HIF1A, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MAOA, MGAM, MIF, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.06812 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CA4, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PTPRS, SLC1A1, TEK, TRPV1 |
3.9972 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PTPRS, SLC1A1, TEK, TRPV1 |
3.78365 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, FLT3, FUT7, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSD17B2, IGF1R, INSR, KDR, MAOA, MET, MGAM, MTNR1A, MTNR1B, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SRC, TBXAS1, TEK, TRPV1, TYR |
3.35688 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, MTNR1A, SMAD3 |
3.34505 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GRIA4, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MAOA, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
3.13785 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.05262 |
|
[CC] GO:0042734 |
None
|
GRIK5, GRM1, GRM3, GRM5, GRM8 |
2.95861 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCHE, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, FLT3, GRIA2, HSD17B2, PTGES, PTGS1, PTGS2, PTPN1, TBXAS1 |
2.8052 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.73943 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA9, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HSPA1A, IGF1R, INSR, KDR, MAOA, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
2.64188 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PTGS2, PTPRS, SRC, TUBB3 |
2.5506 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PTPRS, SRC, TRPV1 |
2.53325 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.46391 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, INSR, PTGS1, PTGS2, PTPRS, SRC, TRPV1, TUBB3 |
2.41969 |
|
[CC] GO:1903561 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.41969 |
|
[CC] GO:0043230 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.41969 |
|
[CC] GO:0097060 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, TRPV1 |
2.27801 |
|
[CC] GO:0044421 |
None
|
ABCB1, ACHE, AKR1B1, AKR1B10, ALOX5, ALPL, APP, AXL, BCHE, CA1, CA2, CA4, CBR1, DUSP3, EGFR, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3, XDH |
2.25008 |
|
[CC] GO:0045121 |
membrane raft
|
APP, BACE1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.22708 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, BACE1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.20977 |
|
[CC] GO:0070062 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.20977 |
|
[CC] GO:0031982 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, APP, AXL, BACE1, CA1, CA2, CA4, CBR1, DUSP3, EGFR, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, KDR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPN1, PTPRS, SLC1A1, SRC, TUBB3, TYR |
2.13696 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, GRIA2, HSD17B2, PTGES, PTGS1, PTGS2, TBXAS1 |
2.0249 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, AURKB, AXL, BACE1, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
17.4589 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DNMT1, ESR1, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PTPN1, SMAD3, TBXAS1, TNKS, TYR, XDH |
11.6235 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
11.5568 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.32644 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, HSD17B1, HSD17B2, MAOA, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.17907 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.54052 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, POLB |
7.17926 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.52753 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC, TBXAS1 |
6.49089 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC, TBXAS1 |
6.19737 |
|
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, HSD17B1, NQO2, POLA1, PTGES, PTGS1, PTGS2, SRC, TBXAS1, XDH |
6.10566 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.06307 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SRC, TEK, TOP2A, TRPV1 |
5.93762 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1, TYR |
5.80725 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.80725 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, XDH |
5.69186 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DNMT1, ESR1, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.64872 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.58063 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, TYR |
5.28131 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.28131 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1, POLB |
5.22709 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DNMT1, ESR1, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.97081 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.85499 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, DNMT1, ESR1, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PTPN1, SMAD3, TNKS |
4.75607 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, SRC, TEK, TERT |
4.69184 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
4.62803 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.59973 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.58929 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, MTNR1A, NQO2 |
4.50914 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, TEK, TRPV1 |
4.45991 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.3201 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
3.95772 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
3.95772 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, EGFR, ESR1, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, TEK, TRPV1 |
3.92824 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, APP, AURKB, AXL, CDK6, CSNK2A1, DAO, DYRK1A, EGFR, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGES, PTPRS, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
3.92824 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
3.92 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
3.91798 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
3.85331 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, TEK, TRPV1 |
3.671 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.55222 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, SMAD3, TEK, TRPV1 |
3.51111 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, APP, BCHE, BCL2, CSNK2A1, DYRK1A, EGFR, ESR1, FLT3, GRIK5, IGF1R, KDR, MET, MIF, MMP9, NQO2, PTGS2, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.36843 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AURKB, BACE1, BCHE, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ESR1, GRM5, HIF1A, HSPA1A, MET, MIF, POLA1, POLB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.20323 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.11167 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
3.0313 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, BACE1, BCHE, GRIA2, INSR |
3.02313 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
2.89319 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
2.85437 |
|
[MF] GO:0033218 |
amide binding
|
ACHE, BACE1, BCHE, GRIA2, IGF1R, INSR, NQO2, PTGES, TUBB3 |
2.7896 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.77437 |
|
[MF] GO:0003990 |
acetylcholinesterase activity
|
ACHE, BCHE |
2.77437 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.77437 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
2.77186 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PTPRS, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.72927 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.6462 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.5506 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APEX1, APP, AURKB, AXL, BACE1, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
2.47967 |
|
[MF] GO:0042277 |
peptide binding
|
ACHE, BACE1, BCHE, GRIA2, IGF1R, INSR, PTGES, TUBB3 |
2.4341 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2, XDH |
2.43308 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DYRK1A, EGFR, ESR1, FLT3, HIF1A, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
2.40059 |
|
[MF] GO:0008502 |
None
|
MTNR1A, MTNR1B |
2.40059 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.40059 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.40059 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.40059 |
|
[MF] GO:0004104 |
cholinesterase activity
|
ACHE, BCHE |
2.40059 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.3517 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.29531 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.25005 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.25005 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DNMT1, DYRK1A, EGFR, ESR1, FLT3, HIF1A, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
2.24845 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, HIF1A, POLA1, PTPN1, SMAD3, SRC, TOP2A |
2.21519 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.19066 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.15361 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.15361 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.15361 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, HIF1A, POLA1, PTPN1, SMAD3, SRC, TOP2A |
2.12352 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.10947 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.0945 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.08957 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, MET, PPARA, PTPN1, SMAD3 |
2.08221 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HIF1A, HSPA1A, KDR |
2.06845 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, NQO2, XDH |
2.02244 |
|
[MF] GO:0030594 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM5 |
2.00463 |
