| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCG2, ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA12, CA2, CA7, CACNA1C, CDK6, CHRM1, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, EDNRA, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GAA, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, INSR, KCNH2, KDR, KIT, MAOA, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
18.9641 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA9, CDK6, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MMP2, MMP9, MPO, PIK3CA, PPARA, PTGES, PTGS2, RELA, RORC, SLC6A4, SRC, TEK, TYR |
17.6063 |
|
[BP] GO:0042221 |
response to chemical
|
ABCG2, ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CES1, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MMP2, MMP9, MPO, PIK3CA, PPARA, PTGES, PTGS2, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
16.5329 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MMP2, MPO, PIK3CA, PPARA, PTGES, PTGS2, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TYR |
16.0675 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APP, AR, BCHE, BCL2, CDC25B, CDK6, CHRM1, CHRNA7, CSNK2A1, CYP1B1, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MAP2K1, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGES, PTGS1, PTGS2, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
13.8933 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CA2, CA7, CHRNA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.1442 |
|
[BP] GO:0033993 |
response to lipid
|
AKR1C3, ALPL, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, IDO1, MPO, PTGES, PTGS2, RELA, RORC, SLC6A4, SRC, TYR |
13.1442 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CA2, CA7, CHRNA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.1442 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA7, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.7936 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA7, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.6372 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CHRNA7, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, KIT, MAP2K1, MET, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
12.6372 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, AR, BCHE, BCL2, CA2, CA9, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, KIT, PPARA, PTGS2, RELA, SLC6A4, SRC, TEK |
12.4756 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA2A, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AR, AXL, BCHE, BCL2, CACNA1C, CHRM1, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESRRB, F3, FABP4, GAA, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, KCNH2, KIT, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CA, PIM1, PPARA, PTGS2, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TNKS2, TYR |
12.4756 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, BCHE, BCL2, CA2, CA9, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, KIT, MMP2, PPARA, PTGS2, RELA, SLC6A4, SMAD3, SRC, TEK |
12.3806 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, APP, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, KIT, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
12.3268 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, KIT, MAP2K1, MET, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
12.3268 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CHRNA7, CYP1B1, EGFR, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SRC, TEK, XDH |
11.7122 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, EGFR, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.6808 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA9, CDK6, CES1, CHRM2, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EDNRA, EGFR, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A, TYR |
11.3236 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
11.152 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, CES1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
11.1234 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MAP2K1, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
11.1084 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, BCHE, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTGES, PTGS2, RELA, RORC, SLC6A4, SRC, TEK, TYR |
10.811 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BCHE, CA2, CA7, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PTGS2, SLC6A4 |
10.811 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BCHE, CA2, CA7, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PTGS2, SLC6A4 |
10.811 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA9, CACNA1C, CDC25B, CDK6, CES1, CHRM1, CHRM2, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, MAP2K1, MET, MMP2, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
10.3208 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CHRNA7, CNR1, CSNK2A1, CYP1B1, EGFR, ESRRA, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IDO1, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.1675 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, AKR1C3, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA7, CA9, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD17B3, HSPA1A, IDO1, MPO, PIK3CA, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.1242 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.64879 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AURKB, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SRC, TEK, XDH |
9.35615 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MMP2, MMP9, PIK3CA, PTGS2, RELA, RORC, SLC6A4, SMAD3, SRC, TERT |
9.18337 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA2A, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRNA3, CHRNA7, CNR1, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, GAA, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, IDO1, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIM1, PTGS2, RELA, SLC1A1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
9.17332 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIK3CA, PIM1, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
9.09791 |
|
[BP] GO:0042493 |
response to drug
|
ABCG2, AKR1B1, APEX1, AXL, BCHE, BCL2, CA9, CDK6, CHRNA3, CHRNA7, CNR1, CNR2, CYP1A1, CYP1B1, EGFR, FABP3, HMGCR, HSD11B2, KCNH2, KDR, PTGS2, RELA, SLC6A2, SLC6A4, SRC |
9.06849 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
8.99527 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EDNRA, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, MAP2K1, PIK3CA, PPARA, RELA, SMAD3, SRC, TEK, TYR |
8.9524 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
ADRA2A, AKR1B1, AKR1C3, AR, BCL2, CDC25B, CDK6, CHRM1, CHRNA7, CSNK2A1, EGFR, ESR1, F3, FLT3, HMGCR, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, PIM1, PTGS2, RELA, TEK, TERT |
8.9524 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, ADRA2A, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, CNR1, EDNRA, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GPR35, GRIK5, GRM1, GRM5, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3, SRC, TERT |
8.87513 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, GAA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, IDO1, MAOA, MPO, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.84621 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EDNRA, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.70087 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, KIT, MMP9, PTGES, PTGS2, RELA, SRC, TERT |
8.67147 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EDNRA, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.61462 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDK6, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, IDO1, IGF1R, KCNH2, KDR, KIT, MAP2K1, MET, MMP12, MMP9, MPO, PIK3CA, PIM1, PPARA, PTGES, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.53485 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1B1, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TNKS, TNKS2 |
8.512 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.35162 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.35162 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, DUSP3, EDNRA, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.28494 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGES, PTGS1, PTGS2, TBXAS1 |
8.2426 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ADRA2A, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CDK6, CHRM1, CHRNA3, CNR1, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MET, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TEK, TERT |
8.1855 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, IGF1R, INSR, KDR, KIT, MMP2, PIK3CA, PTGS2, RELA, RORC, SLC6A4, SMAD3, SRC |
8.08051 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, ADRA2A, AKR1B1, AKR1C3, CACNA1C, CHRNA3, CNR1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
8.02466 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ESRRB, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.99001 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGES, PTGS1, PTGS2, TBXAS1 |
7.9632 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGES, PTGS1, PTGS2, TBXAS1 |
7.96077 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, MPO, PIK3CA, PIM1, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
7.85455 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, ADRA2A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, CNR1, EDNRA, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3 |
7.70712 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.69308 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRA2A, AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MMP2, MMP9, NUAK1, PIK3CA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TERT, TOP2A |
7.66509 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, AKR1C3, ALOX5, CES1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, KIT, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
7.53264 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CES1, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
7.36219 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.25099 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDK6, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KCNH2, KDR, KIT, MAP2K1, MET, MMP12, MMP9, MPO, PIK3CA, PIM1, PPARA, PTGES, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
7.25099 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA2A, APP, AR, CHRNA7, EGFR, FLT3, GRM1, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC, TEK, XDH |
7.20941 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, ADRA2A, CHRNA7, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC |
7.20941 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CHRNA7, CYP1A1, EDNRA, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, KIT, MMP2, MPO, PPARA, PTGS2, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
7.20941 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AURKB, AXL, BCL2, CDK6, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.05351 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ADRA2A, APP, CDK6, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IDO1, IGF1R, MAP2K1, MAP3K7, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, XDH |
6.93831 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EDNRA, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KIT, MAP2K1, MAP3K7, MET, MMP9, PIK3CA, PIK3CB, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.93116 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, ADRA2A, AURKB, BCL2, CA2, CA7, CACNA1C, CDK6, CNR1, EGFR, HCAR2, HMGCR, KDR, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
6.87749 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CHRNA7, CYP1A1, EDNRA, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
6.86601 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CES1, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP2, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
6.85746 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CDK6, CHRM1, CHRM4, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.84598 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KIT, MAP2K1, MAP3K7, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.84598 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA2A, AKR1C3, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.82446 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.81516 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, BCHE, CHRNA3, CHRNA7, CNR1, CNR2, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, RELA, SLC6A4, SRC, TEK, TYR |
6.8117 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, AKR1C3, BCL2, CYP1A1, CYP1A2, CYP1B1, TYR |
6.80375 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.77453 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AKR1C3, APEX1, APP, AR, AXL, CDK6, CYP1B1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PTGS2, RELA, RORC, SLC6A4, SRC |
6.77452 |
|
[BP] GO:0007193 |
None
|
ADORA1, ADRA2A, CHRM1, CHRM2, CHRM4, GRM1, GRM3, GRM5, GRM8 |
6.77211 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CHRNA7, CYP1A1, EDNRA, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
6.75529 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, ESRRB, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
6.7235 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, BCHE, CHRNA7, CNR1, CNR2, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, RELA, SLC6A4, SRC, TEK, TYR |
6.71626 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA2A, AKR1C3, APP, AR, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.67765 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRA2A, CHRM1, CHRM2, CHRM4, CNR1, CNR2, GRM1, GRM3, GRM5, GRM8, HTR6 |
6.63738 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
6.59645 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.59313 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
6.59313 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA2A, APP, AR, AXL, BCL2, CA2, CHRNA7, CNR1, CYP1B1, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, IDO1, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, PIM1, PTGS2, RELA, SLC1A1, SMAD3, SRC, TEK, TERT |
6.54739 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRA2A, APP, AURKB, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
6.51431 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRNA3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESRRA, ESRRB, FLT3, GAA, GBA2, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, MAP2K1, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RELA, RORC, SMAD3, SRC, TEK, TYR |
6.49687 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
BCHE, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, NQO2, PTGS1, RORC |
6.47728 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC |
6.45785 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA2A, APP, AR, CHRNA7, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC, TEK, XDH |
6.44627 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, EGFR, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
6.42019 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.37198 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.36491 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, MPO, PTGS1, PTGS2, RELA, SRC |
6.36084 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CACNA1C, CHRNA3, CHRNA7, CNR1, CNR2, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KCNH2, KDR, SRC |
6.35784 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGES, PTGS1, PTGS2, TBXAS1 |
6.3536 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CHRNA7, CYP1A1, EDNRA, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
6.3536 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, BCHE, BCL2, CHRM1, CHRNA7, CNR1, CNR2, CYP1B1, EDNRA, EGFR, GAA, GRM1, GRM5, GRM8, HMGCR, HSD11B2, INSR, KCNH2, KIT, PIK3CA, PTGS2, SLC6A4, SRC, TEK, TYR |
6.34626 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CES1, CHRNA7, CNR1, CNR2, CYP1A1, CYP1B1, HMGCR, KDR, RELA, SLC6A4, SRC |
6.34043 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.27675 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
6.27521 |
|
[BP] GO:0019371 |
None
|
AKR1C3, PTGES, PTGS1, PTGS2, TBXAS1 |
6.26316 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CACNA1C, CDK6, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.23993 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.18032 |
|
[BP] GO:0032787 |
None
|
AKR1C3, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, GBA2, GLO1, IDO1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
6.13069 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA2A, APP, AURKB, BCL2, CDC25B, CHRNA3, CHRNA7, EDNRA, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.13069 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, AKR1C3, CES1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.12285 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA2A, AKR1B1, AKR1C3, APP, AR, AURKB, AXL, BCL2, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
6.11627 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, BCHE, CHRNA3, CYP1B1, EGFR, GRIK5, INSR, MAOA, PTGS2, SLC1A1, SLC6A2, SLC6A4, SMAD3 |
6.11323 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRA2A, AURKB, CDC25B, CHRNA3, CHRNA7, EGFR, FLT3, GRM1, GRM5, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
6.09939 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRA2A, CDC25B, CHRNA3, CHRNA7, EGFR, FLT3, GRM1, GRM5, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
6.09421 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, ADRA2A, AKR1C3, CNR1, CYP1A1, FABP3, FLT3, HCAR2, HMGCR, KIT, PPARA, PTGS2, RORC, SRC, TEK |
6.09045 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, EGFR, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
6.0512 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.04778 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, AKR1C3, CES1, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
6.04778 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, ADRA2A, CHRNA3, CHRNA7, EGFR, GRM1, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC |
5.99703 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.97865 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, ADRA2A, CHRNA7, EGFR, FLT3, GRM1, INSR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC |
5.96407 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
AKR1C3, ALPL, AXL, BCHE, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, RELA, SLC6A4, SRC, TYR |
5.96407 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.94663 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
5.91379 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP19A1, GLO1, HMGCR, HSD17B3, IDO1 |
5.91074 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CHRM4, CSNK2A1, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MAP3K7, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, RELA, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.90419 |
|
[BP] GO:0048545 |
response to steroid hormone
|
AKR1C3, ALPL, AR, BCHE, BCL2, CA2, EGFR, FLT3, HSD11B2, PTGS2, RELA, SRC |
5.90419 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, MAP3K7, PIM1, PPARA, RELA, RORC, SRC |
5.89182 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ADRA2A, APP, AXL, BCL2, CA2, CA7, CACNA1C, CHRM1, CHRNA3, CNR1, CYP19A1, EGFR, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, INSR, KCNH2, MAP2K1, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TERT |
5.885 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGES, PTGS1, PTGS2, TBXAS1 |
5.88478 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ADRA2A, APP, BCL2, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.85164 |
|
[BP] GO:0009987 |
cellular process
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CACNA1C, CDC25B, CDK6, CES1, CES2, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.84829 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, BCHE, CHRM1, CHRNA7, CNR1, EGFR, GRM5, HMGCR, INSR, KIT, PTGS2, SLC6A4 |
5.84313 |
|
[BP] GO:0007154 |
None
|
ADORA1, AKR1C3, AR, AXL, BCL2, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, PTGS2, SLC1A1, SLC6A2, TEK |
5.83674 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SRC, TEK, XDH |
5.82323 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, EGFR, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.80692 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRA2A, CDC25B, CHRNA3, CHRNA7, EGFR, FLT3, GRM1, GRM5, INSR, KIT, MAP2K1, MAP3K7, PIK3CA, PIK3CB, PTPN1, SRC |
5.77211 |
|
[BP] GO:0065007 |
biological regulation
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GAA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
5.76834 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, APEX1, APP, AXL, BCL2, CA2, CA9, CHRNA7, CNR2, CYP1A1, CYP1A2, CYP1B1, EDNRA, EGFR, HSD11B2, HSPA1A, IDO1, KIT, MAP2K1, MAP3K7, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A |
5.75458 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EDNRA, EGFR, ESR1, FLT3, KIT, MAP2K1, MET, PIK3CB, PIM1, SRC, TEK, TYR |
5.75144 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA2A, CACNA1C, CHRM1, CHRM2, CHRNA3, EGFR, GAA, GPR35, GRM1, HCAR2, KCNH2, KIT, PTGS2, SLC1A1, SMAD3 |
5.72284 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ADRA2A, APP, BCL2, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.67749 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MAP2K1, MET, SRC, TEK |
5.67536 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2, HSD17B3 |
5.64723 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, MMP9, RELA, SRC |
5.64723 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MAP2K1, MET, SRC, TEK |
5.61755 |
|
[BP] GO:0031667 |
response to nutrient levels
|
AKR1C3, ALPL, BCHE, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, RELA, SLC6A4, SRC, TYR |
5.57115 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ADRA2A, APP, BCL2, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.53258 |
|
[BP] GO:0007584 |
response to nutrient
|
AKR1C3, ALPL, BCHE, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, RELA, SLC6A4, TYR |
5.53048 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, CHRNA7, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PTGS2, RELA, SRC, TEK |
5.52583 |
|
[BP] GO:0007610 |
None
|
APP, BCHE, BCL2, CHRNA3, CHRNA7, CNR1, EGFR, GAA, GRM1, GRM5, HMGCR, IDO1, INSR, KIT, PPARA, PTGS2, SLC6A4 |
5.50873 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTGS2, RORC, SLC6A4, SRC |
5.49932 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, EGFR, ESR1, FLT3, GRM5, IGF1R, INSR, KIT, MMP2, PTGS2, RELA, SLC6A4, SMAD3, SRC |
5.49615 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, ADRA2A, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CHRNA7, CNR1, CNR2, CSNK2A1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MAP2K1, MET, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
5.48066 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
5.47491 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, HSD17B3, IDO1, INSR, KIT, MAP2K1, MMP2, MMP9, PTGS2, SLC6A4, SRC, TOP2A |
5.47431 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, SLC6A2 |
5.44035 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, SLC6A2 |
5.44035 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4, SRC, TEK |
5.41665 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
5.41488 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRA2A, CHRM1, CHRM2, CHRM4, CNR1, GRM1, GRM3, GRM5, GRM8 |
5.3965 |
|
[BP] GO:0023052 |
None
|
ADORA1, AR, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, KCNH2, SLC1A1, SLC6A2, TEK |
5.3731 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA2A, AR, BCHE, BCL2, CNR2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TERT, XDH |
5.36644 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ADRA2A, APP, BCL2, EGFR, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
5.36081 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA2A, AR, BCHE, BCL2, CNR2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TERT, XDH |
5.34358 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, CHRNA7, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC |
5.19215 |
|
[BP] GO:0010038 |
response to metal ion
|
AKR1C3, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, KIT, MMP9, PTGES, PTGS2, TERT |
5.14691 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDC25B, CDK6, CES1, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.14407 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.13788 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, AKR1C3, BCHE, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, PTGS2, RELA, SLC6A4, SRC |
5.10759 |
|
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSD17B3, INSR, KIT, MAP2K1, SRC |
5.0517 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
5.0517 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, RELA, SRC |
4.98889 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
4.98618 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, EDNRA, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, KCNH2, PIK3CB, SMAD3 |
4.96437 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGES, PTGS2, RELA, SRC |
4.94074 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
AKR1C3, ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSD17B3, INSR, KIT, MAP2K1, PTGS2, SRC |
4.9263 |
|
[BP] GO:0006940 |
None
|
ADORA1, ADRA2A, CHRM1, CHRM2, CHRNA3, KIT, PTGS2 |
4.90987 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.83063 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, MAP2K1, MPO, PTGS2, RELA, TERT |
4.82284 |
|
[BP] GO:0007611 |
None
|
APP, BCHE, CHRNA7, CNR1, EGFR, GRM5, HMGCR, INSR, KIT, PTGS2, SLC6A4 |
4.74966 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA2A, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TERT, XDH |
4.7411 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, SLC6A2 |
4.71201 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, SLC6A2 |
4.71201 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, CHRNA7, EGFR, FLT3, GRM1, INSR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1, SRC |
4.71135 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, BCL2, CES1, CYP19A1, CYP1A1, CYP1B1, GBA2, HMGCR, HSD17B3, MAOA, TYR |
4.7105 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, AKR1C3, ALPL, AXL, BCHE, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, IDO1, KIT, MMP12, MPO, PTGES, PTGS2, RELA, SLC6A4, SMAD3, SRC, TYR |
4.6873 |
|
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7 |
4.68634 |
|
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7 |
4.68634 |
|
[BP] GO:0007267 |
None
|
ADORA1, AR, CHRM1, CHRM2, CHRM4, CHRNA3, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, SLC6A2, TEK |
4.68494 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCHE, BCL2, CDK6, CYP1B1, FABP3, HSPA1A, IDO1, MAP2K1, PTGES, PTGS2, SLC6A4, SMAD3, TERT, XDH |
4.68099 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F3, FABP4, HMGCR, IDO1, KDR, MAP2K1, MET, MMP12, PPARA, PTGS2, RELA, SMAD3, TEK |
4.66963 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGES, PTGS2, RELA, SRC |
4.66814 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, MAP2K1, PIK3CA, RELA, SMAD3, TYR |
4.6505 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
4.64501 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, HSPA1A, IDO1, MAP3K7, MMP12, MMP2, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK |
4.64278 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, RELA, SRC |
4.60114 |
|
[BP] GO:0008217 |
None
|
ADORA1, AR, CNR1, EDNRA, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
4.57915 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, AKR1C3, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, GBA2, GLO1, IDO1, MPO, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.56118 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, CACNA1C, CHRNA7, EDNRA, EGFR, ESR1, GPR35, GRM1, GRM5, KCNH2, PIK3CB, SMAD3 |
4.55203 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AKR1C3, AOX1, AURKB, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, FABP4, FUT7, GAA, GBA2, HSPA1A, IDO1, MAOA, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CB, SRC, XDH |
4.54931 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.53403 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2, TERT |
4.48998 |
|
[BP] GO:0060078 |
None
|
ADORA1, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM5 |
4.45408 |
|
[BP] GO:0031960 |
response to corticosteroid
|
AKR1C3, ALPL, BCHE, BCL2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
4.44718 |
|
[BP] GO:0006693 |
None
|
AKR1C3, CES2, PTGES, PTGS1, PTGS2 |
4.43737 |
|
[BP] GO:0006692 |
None
|
AKR1C3, CES2, PTGES, PTGS1, PTGS2 |
4.43737 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRA2A, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
4.42008 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, MAP2K1, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.41048 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4, SRC, TEK |
4.40518 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CES1, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.378 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, ADRA2A, BCL2, CNR1, EGFR, HCAR2, MET, PIK3CA, PPARA, RELA, SMAD3 |
4.326 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRA2A, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MAP3K7, MET, PIK3CA, PIK3CB, PPARA, PTPN1, RELA, SMAD3 |
4.32532 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MAP3K7, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
4.28544 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, BCHE, CYP1A1, EGFR, PTGS2, RELA, TYR |
4.28544 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PTGS2, RELA, SMAD3, TEK |
4.27819 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA2A, AKR1C3, APP, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EDNRA, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, INSR, PIK3CA, PIK3CB, SRC |
4.26326 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, AOX1, BCHE, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, HSPA1A, IDO1, MAOA, MPO |
4.25503 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CDK6, CHRNA3, CHRNA7, CNR1, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, IDO1, INSR, KDR, KIT, MAP2K1, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
4.22104 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
4.20351 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, ADRA2A, APP, BCL2, CA2, CA7, CACNA1C, CHRM1, CHRNA3, CNR1, GPR35, GRM5, KCNH2, MMP9, PTGS2, SLC6A4 |
4.19567 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.17804 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4 |
4.17575 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4 |
4.17575 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
4.15516 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, HMGCR |
4.15224 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, GBA2, GLO1, IDO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.12768 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, GBA2, GLO1, IDO1, MPO, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.1054 |
|
[BP] GO:0046686 |
response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, KIT, MMP9, TERT |
4.0827 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KCNH2, KDR, PTGS2, RELA, SRC |
4.05914 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
4.05584 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, APEX1, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EDNRA, ESR1, GAA, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, SMAD3 |
4.04756 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.04361 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.04148 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, KIT, PPARA, RORC, SLC6A4, SRC, TOP2A |
4.03785 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
4.03785 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EDNRA, EGFR, ESR1, GPR35, GRM1, GRM5, KCNH2, PIK3CB, SMAD3 |
4.03596 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA2A, CACNA1C, CHRM1, CHRM2, EGFR, GAA, KCNH2, PTGS2, SLC1A1 |
4.02604 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2 |
4.01793 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4 |
3.99638 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA2A, CHRM1, EDNRA, EGFR, HMGCR, PTGS2, SLC6A4 |
3.97305 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, BCHE, CHRM1, CHRNA7, CNR1, CNR2, CYP1B1, EGFR, GAA, GRM1, GRM5, GRM8, HMGCR, INSR, KIT, PTGS2, SLC6A4, TYR |
3.90748 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CHRNA7, CNR1, CYP1B1, ESRRB, F3, HMGCR, IDO1, INSR, KDR, KIT, MAP2K1, PIM1, PTGS2, RELA, SMAD3, SRC, TEK, TERT |
3.89524 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.8888 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, AKR1C3, ALPL, APP, AR, AXL, BCHE, BCL2, CDC25B, CDK6, CES1, CHRNA7, CYP1A1, EDNRA, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, KDR, KIT, MAP2K1, MET, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
3.86539 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, SMAD3 |
3.84056 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
ADRA2A, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CHRNA7, CNR1, CSNK2A1, DUSP3, EDNRA, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
3.83486 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
3.83403 |
|
[BP] GO:0061370 |
testosterone biosynthetic process
|
AKR1C3, CYP19A1, HSD17B3 |
3.83403 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, MAP2K1, TERT |
3.82619 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, ADRA2A, BCL2, CNR1, GPR35, KCNH2, MMP9, PTGS2 |
3.80714 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AR, AXL, BCL2, CA2, CDK6, CHRNA3, CHRNA7, CNR1, CYP1B1, EGFR, ESR1, ESRRA, F3, HMGCR, IDO1, INSR, KDR, KIT, MAP2K1, PIM1, PTGS2, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
3.80376 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.78584 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, BCHE, CNR2, PTGS2, SLC6A4 |
3.78584 |
|
[BP] GO:0000187 |
activation of MAPK activity
|
CHRNA7, GRM1, INSR, KIT, MAP2K1, MAP3K7, PIK3CB, PTPN1 |
3.76667 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
3.76575 |
|
[BP] GO:0044283 |
None
|
AKR1B1, AKR1C3, ALOX5, CES1, CYP19A1, CYP1A1, HMGCR, HSD17B3, IDO1, MPO, PTGES, PTGS1, PTGS2 |
3.75907 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.69334 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA2A, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.64255 |
|
[BP] GO:0097756 |
None
|
ADORA1, EDNRA, HMGCR, PTGS2, SLC6A4 |
3.62315 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, AKR1C3, GBA2 |
3.62315 |
|
[BP] GO:0060079 |
None
|
ADORA1, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.60845 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR |
3.59443 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, IDO1, KIT, MAP3K7, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, RELA, SMAD3, SRC |
3.57984 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, RELA, SRC |
3.57133 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.56643 |
|
[BP] GO:0001775 |
cell activation
|
ADRA2A, ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, GAA, HSPA1A, KIT, MGAM, MMP9, MPO, PIK3CA, PIK3CB, RORC, SMAD3, SRC |
3.4991 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GRM5, IGF1R, INSR, MMP2, PTGS2, RELA, SLC6A4, SRC |
3.49868 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, ADRA2A, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, EGFR, HCAR2, INSR, KCNH2, MMP12, PTGS2, SLC6A4, SMAD3, SRC, TERT |
3.47573 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, APP, BCL2, CACNA1C, CHRNA7, EDNRA, EGFR, ESR1, GPR35, GRM1, GRM5, KCNH2, PIK3CB, SMAD3 |
3.4627 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MMP9, PTGS2, PTPN1, RELA, SRC, TERT |
3.45941 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC, TEK |
3.42851 |
|
[BP] GO:0006937 |
None
|
ADORA1, ADRA2A, CACNA1C, CHRM1, CHRM2, CHRNA3, KIT, PTGS2 |
3.41621 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, MAP2K1, MAP3K7, PTPN1, XDH |
3.39705 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
APP, CHRNA7, DUSP3, EGFR, HMGCR, KDR, MAP2K1, PTPN1, SRC, TEK |
3.39157 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, MAP2K1, PIM1, PTGS2, SLC6A4, SMAD3, SRC, TERT, TNKS, TOP2A |
3.39117 |
|
[BP] GO:0070302 |
regulation of stress-activated protein kinase signaling cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, MAP2K1, MAP3K7, PTPN1, XDH |
3.3856 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, CNR1, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.36796 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
3.36796 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTGES, PTGS2, RELA, SMAD3, SRC |
3.34047 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
ADRA2A, AKR1C3, APEX1, AR, EGFR, ESR1, FLT3, INSR, KIT, RELA, SRC |
3.33823 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.31515 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EDNRA, EGFR, ESR1, MET, SMAD3, SRC |
3.29777 |
|
[BP] GO:0050995 |
None
|
ADORA1, ADRA2A, CNR1, HCAR2 |
3.29419 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.29419 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
3.29419 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
AKR1C3, BCL2, CYP1B1, EGFR, INSR, PTGS2, SMAD3, XDH |
3.28435 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, CHRNA7, EDNRA, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
3.28225 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, CHRNA7, EGFR, PTGS2 |
3.28225 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MAP2K1, MAP3K7, MET, NUAK1, PTGS2, PTPN1, TERT, XDH |
3.279 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.26334 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PPARA, PTGS2, SRC, TEK |
3.24011 |
|
[BP] GO:0090257 |
None
|
ADORA1, ADRA2A, CACNA1C, CHRM1, CHRM2, CHRNA3, KIT, PTGS2, SMAD3 |
3.22571 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AKR1C3, AR, AXL, CDK6, EGFR, ESR1, FLT3, RELA, RORC, SLC6A4, SRC |
3.20977 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GAA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.20382 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GRM5, IGF1R, INSR, MMP2, PTGS2, RELA, SLC6A4, SRC |
3.19497 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
3.19446 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CHRNA7, CYP1B1, F3, KDR, KIT, PTGS2, TEK, TERT |
3.19317 |
|
[BP] GO:0050730 |
None
|
ADORA1, ADRA2A, APP, EGFR, FLT3, GRM5, KIT, PTPN1, SRC |
3.18973 |
|
[BP] GO:0044597 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.18111 |
|
[BP] GO:0044598 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.18111 |
|
[BP] GO:0030638 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.18111 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.16515 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
3.16515 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2, TERT |
3.15038 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTGES, PTGS2, RELA, SMAD3, SRC |
3.14266 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, RELA, SLC6A4, TEK, TYR |
3.10862 |
|
[BP] GO:0007200 |
None
|
ADRA2A, CHRM1, CHRM2, CHRM4, ESR1, GRM5 |
3.09678 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, RELA, SRC, XDH |
3.08245 |
|
[BP] GO:0050994 |
None
|
ADORA1, ADRA2A, CNR1, HCAR2, PPARA |
3.07618 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.06965 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, INSR, SLC6A4, SRC, TERT |
3.06597 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.03504 |
|
[BP] GO:0030647 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.02432 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
AKR1C3, EGFR, INSR, PTGS2, SMAD3, XDH |
3.0219 |
|
[BP] GO:0007612 |
None
|
APP, BCHE, GRM5, HMGCR, INSR, KIT, PTGS2 |
2.99302 |
|
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3 |
2.97168 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
2.96767 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA2A, APP, AR, BCL2, CDC25B, CHRNA3, CHRNA7, CSNK2A1, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
2.94501 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCHE, BCL2, EGFR, FLT3, HSD11B2, PTGS2 |
2.93588 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, SRC, TEK, TNKS, TOP2A |
2.93482 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
ADRA2A, APP, AR, BCL2, CACNA1C, CHRM1, CHRNA3, CSNK2A1, EGFR, GRIK5, HMGCR, MAP2K1, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.90458 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, AR, CYP1B1, ESR1, ESR2, HSPA1A, KIT, MAP3K7, PIM1, RELA |
2.90016 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.89752 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, GRM5 |
2.88393 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
APP, CHRNA7, EGFR, HMGCR, KDR, MAP2K1, SRC, TEK |
2.85822 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
2.85435 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, TERT |
2.84726 |
|
[BP] GO:0032845 |
None
|
ADORA1, ADRA2A, BCL2, HMGCR, SRC, TNKS, TNKS2 |
2.84726 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA2A, AR, BCL2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, RELA, SMAD3, SRC, TERT, XDH |
2.8353 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.83129 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTGS2, RELA, SLC6A4, TEK, TYR |
2.81181 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
2.8103 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.80687 |
|
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, AKR1C3, HMGCR |
2.80687 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.80687 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MPO |
2.80687 |
|
[BP] GO:1904645 |
response to amyloid-beta
|
APP, CHRNA7, GRM5, IGF1R |
2.80687 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, ADRA2A, APP, CA2, CACNA1C, CHRM1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.79401 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, ADRA2A, CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, HCAR2, HMGCR |
2.79372 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
AKR1C3, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.78395 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, RELA |
2.77261 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.76775 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.76775 |
|
[BP] GO:0071276 |
cellular response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, MMP9 |
2.75687 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
2.75687 |
|
[BP] GO:0016488 |
None
|
AKR1B10, AKR1C3 |
2.75687 |
|
[BP] GO:0016487 |
None
|
AKR1B10, AKR1C3 |
2.75687 |
|
[BP] GO:0016107 |
None
|
AKR1B10, AKR1C3 |
2.75687 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.75687 |
|
[BP] GO:0006714 |
None
|
AKR1B10, AKR1C3 |
2.75687 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, MPO |
2.75687 |
|
[BP] GO:0051172 |
None
|
ADRA2A, APEX1, APP, AR, AURKB, CHRNA7, CSNK2A1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
2.73881 |
|
[BP] GO:2001237 |
negative regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, HSPA1A, RELA, SRC, TERT |
2.73485 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, APP, BCL2, CACNA1C, CHRNA7, EDNRA, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3 |
2.73418 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, RELA, SRC |
2.72615 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, AKR1C3, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.72615 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA2A, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, EGFR, GRM5, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PTPN1, RELA, SRC, TEK |
2.7215 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, EGFR, ESR2, HSPA1A, INSR, MPO, PIK3CA, PIM1, SLC6A4, SMAD3, TNKS2 |
2.70361 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AR, AXL, BCL2, CA2, CA9, CACNA1C, CHRNA7, CYP1B1, EDNRA, EGFR, ESR1, GAA, INSR, MET, MMP2, RELA, SLC6A4, SMAD3, SRC, TEK |
2.70192 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CHRNA7, CYP1B1, F3, KDR, PTGS2, TEK, TERT |
2.69777 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
2.6726 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.6726 |
|
[BP] GO:1902893 |
None
|
PPARA, RELA, SMAD3, TERT |
2.6726 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.6726 |
|
[BP] GO:0106027 |
None
|
APP, CHRNA7, IGF1R, INSR |
2.6726 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EDNRA, EGFR, ESR1, KIT |
2.6726 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.67246 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, CHRNA3, CHRNA7, CNR1, CSNK2A1, EGFR, ESR1, ESR2, GRIK5, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MET, MMP1, MMP9, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.67046 |
|
[BP] GO:0006081 |
None
|
AKR1B10, AKR1C3, CYP1B1, GLO1, RELA |
2.67001 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, ADRA2A, APP, AR, BCL2, CACNA1C, CHRM1, CNR1, CSNK2A1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.66227 |
|
[BP] GO:0031349 |
positive regulation of defense response
|
CNR1, EGFR, FABP4, HSPA1A, IDO1, MAP3K7, MMP12, MMP2, PTGS2, RELA, SRC |
2.6605 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PTGS2, RELA, SRC, TEK |
2.64272 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.63987 |
|
[BP] GO:0008406 |
gonad development
|
AKR1C3, BCL2, CYP19A1, ESR1, INSR, KIT |
2.63946 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, IDO1, KDR, MET, PTGS2, SMAD3 |
2.63431 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CHRNA3, CHRNA7, CSNK2A1, CYP1B1, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
2.63341 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.61063 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, IDO1, KDR, MAP3K7, NUAK1, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
2.61063 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, AKR1C3, CES1, CYP19A1, HMGCR, HSD17B3, TYR |
2.57916 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
2.57916 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.57769 |
|
[BP] GO:0001516 |
None
|
PTGES, PTGS1, PTGS2 |
2.57769 |
|
[BP] GO:0046457 |
None
|
PTGES, PTGS1, PTGS2 |
2.57769 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, EGFR, HMGCR, KIT, PTGS2, RELA, TYR |
2.57293 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EDNRA, EGFR, ESR1, MET, SMAD3, SRC |
2.57024 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EDNRA, EGFR, ESR1, KIT |
2.54571 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, ADRA2A, CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, GRIK5, HCAR2, HMGCR, MMP12, SLC6A4, SRC |
2.53453 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, AXL, CNR2, KIT, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2, RELA |
2.52766 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.52766 |
|
[BP] GO:1900543 |
None
|
ADRA2A, EDNRA, GRM3, GRM8, PPARA |
2.51174 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, MAP2K1, TEK, TYR |
2.51076 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, SMAD3, TEK |
2.50998 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX5, PTGES, PTGS1, PTGS2 |
2.505 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.49232 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC, TEK |
2.49115 |
|
[BP] GO:0045980 |
None
|
ADRA2A, EDNRA, GRM3, GRM8, PPARA |
2.49115 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.49115 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MAP2K1, MET, MMP12, PPARA, PTGS2, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.46725 |
|
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1, HSD17B3 |
2.46725 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, MMP12, PPARA, SMAD3, TEK |
2.45806 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CDK6, CHRM2, CYP1A1, EGFR, HSD11B2, HSPA1A, IDO1, INSR, KDR, MAP2K1, MET, MMP1, MMP12, MPO, RELA, SLC6A4, SMAD3, SRC |
2.45237 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
AKR1C3, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.44385 |
|
[BP] GO:0071383 |
None
|
AKR1C3, AR, EGFR, FLT3, SRC |
2.44255 |
|
[BP] GO:0061097 |
None
|
ADORA1, ADRA2A, APP, GRM5, PTPN1 |
2.44255 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, ADRA2A, FLT3, GRM5, KIT, PTPN1, SRC |
2.43141 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, RELA |
2.42423 |
|
[BP] GO:0048731 |
system development
|
ACHE, ADORA1, ALPL, CACNA1C, CHRM1, CHRM2, CHRNA3, EDNRA, HSD17B3, MMP9, PIK3CA, SMAD3, SRC, TEK |
2.41883 |
|
[BP] GO:1903798 |
None
|
EGFR, ESR1, MAP2K1 |
2.4141 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.4141 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, RELA, SRC |
2.36776 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MAP2K1, MET, MMP12, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.36776 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, PTGS2, SLC6A4 |
2.36776 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MMP9, PTGS2, PTPN1, RELA, SMAD3, SRC, TERT |
2.36776 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.36776 |
|
[BP] GO:0033590 |
None
|
EGFR, RELA |
2.36776 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.36776 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.36776 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.36776 |
|
[BP] GO:1905144 |
None
|
CHRNA3, CHRNA7 |
2.36776 |
|
[BP] GO:0032227 |
negative regulation of synaptic transmission, dopaminergic
|
PTGS2, SLC6A4 |
2.36776 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.36776 |
|
[BP] GO:0016095 |
None
|
AKR1B10, AKR1C3 |
2.36776 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.36776 |
|
[BP] GO:0035094 |
response to nicotine
|
BCL2, CHRNA7, CNR1, RELA |
2.36776 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.36776 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, EGFR, PPARA, SMAD3 |
2.36472 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.35205 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.34984 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.34984 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.34984 |
|
[BP] GO:0051091 |
positive regulation of DNA binding transcription factor activity
|
APP, AR, ESR1, ESR2, HSPA1A, KIT, MAP3K7, RELA |
2.34027 |
|
[BP] GO:1901224 |
None
|
APP, EGFR, MAP3K7, RELA |
2.33178 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, AKR1C3, BCHE, CSNK2A1, MAOA |
2.32603 |
|
[BP] GO:0045833 |
None
|
ADORA1, ADRA2A, AKR1C3, CNR1, HCAR2 |
2.31488 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, EGFR, ESR1, KIT, PTGS2, SLC6A4, SRC |
2.30685 |
|
[BP] GO:0008150 |
biological_process
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CDC25B, CDK6, CES1, CES2, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.29891 |
|
[BP] GO:0045934 |
None
|
ADRA2A, APEX1, AR, AURKB, EDNRA, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2 |
2.29756 |
|
[BP] GO:0061098 |
None
|
ADORA1, ADRA2A, GRM5, PTPN1 |
2.29756 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.29756 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR6, KDR, KIT, MAP2K1, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.28577 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.27896 |
|
[BP] GO:0001504 |
None
|
SLC1A1, SLC6A2, SLC6A4 |
2.27896 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CHRNA3, CHRNA7, CSNK2A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
2.2778 |
|
[BP] GO:0070201 |
None
|
ACHE, ADRA2A, APP, BCL2, CACNA1C, CHRM1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.27779 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PTGS2, SMAD3, SRC, TERT |
2.27624 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, IDO1, PIK3CB |
2.27624 |
|
[BP] GO:0050673 |
epithelial cell proliferation
|
ESR1, KIT, MAP2K1, PIK3CB, TEK |
2.27624 |
|
[BP] GO:0030818 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.26802 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, TERT |
2.26802 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, ADRA2A, CACNA1C, CHRNA3, CNR1, CYP19A1, EGFR, GRIK5, HCAR2, HMGCR, MMP12, SLC6A4, SRC |
2.26714 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
ADRA2A, CYP1B1, HSPA1A, IDO1, MAP3K7, MMP12, PTGS2, RELA, SMAD3, SRC |
2.26403 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
2.25622 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, KIT, PTGS2 |
2.25622 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR6, KDR, KIT, MAP2K1, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.25622 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.23408 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.23347 |
|
[BP] GO:0009411 |
response to UV
|
AURKB, BCL2, EGFR, PTGS2, RELA, TYR |
2.23002 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MAP2K1, MET, MMP12, PPARA, PTGS2, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.22703 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR6, KDR, KIT, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.22621 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.20665 |
|
[BP] GO:0030803 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.20101 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
AKR1C3, MMP1, MMP12, MMP2, MMP9 |
2.19117 |
|
[BP] GO:0042058 |
None
|
ADORA1, ADRA2A, APP, EGFR, MMP9 |
2.19117 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.17724 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AKR1C3, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, FABP3, FABP4, GAA, GBA2, HSPA1A, IDO1, MAOA, MGAM, MPO, PIK3CB, SRC, XDH |
2.17127 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CHRNA7, CYP1B1, F3, KDR, KIT, PTGS2, TEK, TERT, XDH |
2.16891 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, KIT, MMP9, RORC |
2.1583 |
|
[BP] GO:0030154 |
cell differentiation
|
AKR1C3, ALPL, AR, AXL, BCHE, BCL2, CDK6, CES1, CYP1A1, ESR1, FABP4, FLT3, FUT7, GLO1, HMGCR, KDR, KIT, MAP2K1, MMP2, MMP9, PTGS2, RORC, SMAD3, TOP2A |
2.15298 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.15187 |
|
[BP] GO:0042133 |
neurotransmitter metabolic process
|
ACHE, BCHE, CYP1B1, MAOA, SLC6A4 |
2.15075 |
|
[BP] GO:0030815 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.14013 |
|
[BP] GO:0032868 |
None
|
FABP3, HSD11B2, INSR, PPARA, RELA, SRC |
2.14013 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, ADRA2A, APP, BCL2, CNR1, GPR35, HMGCR, HSPA1A, KCNH2, MMP9, PTGS2 |
2.1196 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.1196 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.1196 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.1196 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.1196 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.1196 |
|
[BP] GO:1900372 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.11651 |
|
[BP] GO:2000351 |
None
|
AKR1C3, KDR, TEK, TERT |
2.11651 |
|
[BP] GO:0030809 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.11651 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EDNRA, EGFR, ESR1, KIT |
2.11651 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA, SLC1A1 |
2.09884 |
|
[BP] GO:0030800 |
None
|
ADRA2A, EDNRA, GRM3, GRM8 |
2.08578 |
|
[BP] GO:0008584 |
None
|
AKR1C3, BCL2, ESR1, INSR, KIT |
2.07862 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.05969 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.04751 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.0406 |
|
[BP] GO:0032094 |
None
|
CYP1A1, HSD11B2, MPO |
2.0406 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.02678 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.02678 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.02678 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, KDR, SRC |
2.02678 |
|
[BP] GO:0051223 |
None
|
ACHE, ADRA2A, APP, CACNA1C, CHRM1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.02173 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
ADRA2A, APEX1, BCL2, CNR1, ESRRB, HSPA1A, INSR, KDR, MAP3K7, MET, PIK3CA, PIK3CB, PPARA, PTPN1 |
2.01679 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, FUT7, KIT, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.01197 |
|
[BP] GO:0051591 |
None
|
APEX1, APP, RELA, TEK, TYR |
2.00339 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.00339 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, AKR1C3, BCL2, HSD11B2 |
2.00339 |
|
[BP] GO:0098900 |
None
|
CACNA1C, CNR1, CNR2, GPR35 |
2.00111 |
|
[BP] GO:0019233 |
None
|
CNR1, CNR2, GRM1, PTGS2 |
2.00111 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.00111 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, EDNRA, EGFR, ESR1, F3, FLT3, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PTPN1, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT |
9.18337 |
|
[CC] GO:0016020 |
membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, ALOX5, ALPL, APP, AR, AXL, BCHE, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EDNRA, EGFR, ESR1, F3, FLT3, FUT7, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TYR |
8.54767 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCG2, ADORA1, ADRA2A, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, MGAM, PTGS2, SLC1A1, SRC, TEK |
8.08051 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCG2, ADORA1, ADORA3, ADRA2A, APP, AXL, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, DUSP3, EDNRA, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, MGAM, PTGS2, SLC1A1, SLC6A2, SLC6A4, SRC, TEK |
7.47664 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA2A, APP, AXL, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EDNRA, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR6, IGF1R, INSR, KDR, MET, SLC1A1, SLC6A2, SLC6A4, TEK |
5.885 |
|
[CC] GO:0044425 |
membrane part
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MET, MGAM, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC6A2, SLC6A4, SRC, TBXAS1, TEK, TYR |
5.81568 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
5.61852 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, SLC6A4, SRC |
5.3965 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA2A, APP, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EDNRA, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR6, IGF1R, INSR, KDR, MET, SLC1A1, SLC6A2, SLC6A4, TEK |
5.19215 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, ADRA2A, APP, CHRNA3, CHRNA7, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
5.10759 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, BCHE, PTGES |
5.06277 |
|
[CC] GO:0045121 |
membrane raft
|
APP, CHRNA3, CHRNA7, CNR1, EGFR, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
4.70148 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, CHRNA3, CHRNA7, CNR1, EGFR, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
4.68042 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCHE, BCL2, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, PTGES, PTGS1, PTGS2, PTPN1, TBXAS1 |
4.25436 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, CA2, CHRM1, CHRM2, CHRNA3, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PTGS2, SLC6A2, SLC6A4, SRC |
4.006 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCHE, BCL2, CA1, CA2, CA4, CA7, CACNA1C, CDC25B, CDK6, CES1, CES2, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MGAM, MMP2, MMP9, MPO, NQO2, PIK3CA, PIK3CB, PIM1, PTGES, PTGS1, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.95601 |
|
[CC] GO:0098589 |
membrane region
|
APP, CHRNA3, CHRNA7, CNR1, EGFR, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
3.93622 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.85283 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, CA2, CDK6, CHRM1, CHRM2, CHRNA3, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR6, PIK3CA, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
3.66283 |
|
[CC] GO:0014069 |
None
|
ADORA1, CACNA1C, CHRM1, CHRNA3, GRIK5, GRM1, GRM3, GRM5, SRC |
3.66283 |
|
[CC] GO:0099572 |
None
|
ADORA1, CACNA1C, CHRM1, CHRNA3, GRIK5, GRM1, GRM3, GRM5, SRC |
3.66283 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES1, CES2, CYP19A1, FLT3, GBA2, GRIK5, HMGCR, HSD17B3, HSPA1A, KDR, MAP2K1, PTGS2, PTPN1, XDH |
3.60845 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM3 |
3.45941 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, CA2, CDK6, CHRM1, CHRM2, CHRNA3, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR6, PIK3CA, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
3.30152 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, CA2, CACNA1C, CHRM1, CHRM2, CHRNA3, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IDO1, INSR, PTGS1, PTGS2, SLC6A2, SLC6A4, SRC |
3.23952 |
|
[CC] GO:0044464 |
cell part
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CDC25B, CDK6, CES1, CES2, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.22571 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, PTGES, PTGS1, PTGS2, TBXAS1 |
3.22029 |
|
[CC] GO:0031224 |
None
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR6, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, PTGES, SLC1A1, SLC6A2, SLC6A4, TBXAS1, TEK, TYR |
2.596 |
|
[CC] GO:0043226 |
organelle
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA9, CACNA1C, CDK6, CES1, CES2, CHRM1, CHRNA3, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HMGCR, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MAP2K1, MAP3K7, MGAM, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RELA, RORC, SHBG, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.50411 |
|
[CC] GO:0098802 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM1, INSR |
2.41883 |
|
[CC] GO:0016021 |
None
|
ABCG2, ADORA1, ADORA3, ADRA2A, ALPL, APP, AXL, CA12, CA14, CA9, CACNA1C, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR6, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, PTGES, SLC1A1, SLC6A2, SLC6A4, TBXAS1, TEK, TYR |
2.32958 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, ADRA2A, CA2, CA4, CA9, EGFR, TEK |
2.27779 |
|
[CC] GO:0044853 |
plasma membrane raft
|
CHRNA3, CHRNA7, INSR, PTGS2, SRC |
2.09884 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CES1, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, F3, FLT3, FUT7, GAA, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGES, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
13.4604 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA2A, AR, AXL, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, PPARA, RORC, TEK |
12.7936 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
12.2682 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA2A, AR, AXL, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, PPARA, RORC, SMAD3, TEK |
12.1615 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA2A, AR, AXL, CDK6, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, PPARA, RORC, TEK |
11.6704 |
|
[MF] GO:0043167 |
ion binding
|
ABCG2, ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CDK6, CHRNA3, CHRNA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.5757 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA2A, AR, AXL, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KCNH2, KDR, KIT, MET, PPARA, RORC, TEK |
11.3917 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, IDO1, MAOA, MPO, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
9.94557 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.09791 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA2A, AXL, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KDR, KIT, MET, TEK |
8.44351 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA2A, AXL, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, EDNRA, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6, IGF1R, INSR, KDR, KIT, MET, TEK |
8.44351 |
|
[MF] GO:0008144 |
drug binding
|
ABCG2, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CHRNA3, CHRNA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SLC6A4, SRC, TEK, TOP2A |
8.20501 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR6 |
7.74854 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, CHRNA3, CHRNA7, EGFR, HSD17B1, IGF1R, INSR, NQO2, SHBG |
7.55428 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.45885 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.26318 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
7.07124 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, BCHE, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CHRNA3, CHRNA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, ESR1, ESR2, ESRRA, ESRRB, GLO1, IDO1, KIT, MAP3K7, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
6.87994 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AKR1C3, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, XDH |
6.83536 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, HMGCR, HSD11B2, HSD17B1, IDO1, MPO, NQO2, PTGES, PTGS1, PTGS2, SRC, TBXAS1, XDH |
6.80375 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
6.79365 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
6.63913 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC, SHBG |
6.36084 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PTPN1, RORC, SMAD3, TNKS |
6.28048 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, ADRA2A, AOX1, APP, BCHE, BCL2, CHRNA7, CSNK2A1, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KCNH2, KDR, KIT, MAP3K7, MET, MMP9, NQO2, PTGS2, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
6.04778 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.8211 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MAP2K1, MET, SRC, TEK |
5.77211 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
5.75708 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.67749 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.67749 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.67749 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.65733 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, ESR1, ESR2, ESRRA, ESRRB, GLO1, IDO1, KIT, MAP3K7, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC6A2, SLC6A4, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.61755 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, PTGS1, PTGS2, TBXAS1, TYR |
5.41665 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.37362 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, AKR1C3, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.33553 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
5.28781 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7 |
5.20887 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.17737 |
|
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, TBXAS1, TYR |
4.96877 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR, KIT |
4.83063 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.71262 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, ADRA2A, AOX1, BCL2, CHRNA7, FLT3, HMGCR, KCNH2, KIT, NQO2, PTGS2, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
4.59593 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.46771 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, TBXAS1, XDH |
4.34217 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TERT |
4.26472 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, RELA, SLC6A4, SMAD3, SRC |
4.006 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADORA1, ADRA2A, AOX1, AR, AXL, BCL2, CHRNA7, EGFR, FLT3, HMGCR, KCNH2, KIT, NQO2, PTGS2, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
3.92709 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
3.89524 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, RELA, SLC6A4, SMAD3, SRC |
3.8702 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
3.83403 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRA2A, APP, AR, AURKB, BCHE, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, KCNH2, KIT, MET, PPARA, PTGS2, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.83273 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.57133 |
|
[MF] GO:0047035 |
testosterone dehydrogenase (NAD+) activity
|
AKR1C3, HSD17B2, HSD17B3 |
3.56643 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AKR1C3, AOX1, XDH |
3.3856 |
|
[MF] GO:0098960 |
None
|
CHRNA3, CHRNA7, GRM1, GRM5 |
3.36796 |
|
[MF] GO:0003674 |
molecular_function
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA2A, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CDC25B, CDK6, CES1, CES2, CHRM1, CHRM2, CHRM4, CHRNA3, CHRNA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, DUSP3, EDNRA, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, KIT, MAOA, MAP2K1, MAP3K7, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGES, PTGS1, PTGS2, PTPN1, RELA, RORC, SHBG, SLC1A1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.35322 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
3.34261 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
EGFR, INSR, KDR, KIT, MAP2K1, MAP3K7, SMAD3 |
3.26224 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.22571 |
|
[MF] GO:0005231 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.22571 |
|
[MF] GO:0043168 |
anion binding
|
ABCG2, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, EGFR, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGES, RELA, SLC1A1, SRC, TEK, TOP2A, XDH |
3.1912 |
|
[MF] GO:0022824 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.15417 |
|
[MF] GO:0022835 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
3.15417 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SLC1A1, SRC, TEK, TOP2A, XDH |
3.05675 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.03504 |
|
[MF] GO:0008227 |
None
|
ADRA2A, CHRM1, CHRM2, CHRM4, HTR6 |
2.89752 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, BCHE, CHRNA7, GRIA2, INSR |
2.80368 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.75687 |
|
[MF] GO:0045550 |
None
|
AKR1B10, AKR1C3 |
2.75687 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.75687 |
|
[MF] GO:0003990 |
acetylcholinesterase activity
|
ACHE, BCHE |
2.75687 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.75687 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.64156 |
|
[MF] GO:0016788 |
None
|
ACHE, ADORA1, ALPL, APEX1, BCHE, CA1, CA2, CDC25B, CES1, CES2, CHRM1, DUSP3, EDNRA, MAP2K1, PTPN1 |
2.63341 |
|
[MF] GO:0008289 |
lipid binding
|
AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC, SHBG |
2.57023 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.56358 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.55257 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
2.54571 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
2.54571 |
|
[MF] GO:0005524 |
ATP binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.52287 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA2A, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EDNRA, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR6 |
2.49838 |
|
[MF] GO:0015926 |
None
|
GAA, GBA2, MGAM |
2.49232 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HTR6 |
2.46725 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, BCHE, CHRNA3, CHRNA7, SLC6A4 |
2.46581 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.44255 |
|
[MF] GO:0005230 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5 |
2.41883 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.39781 |
|
[MF] GO:0047718 |
None
|
AKR1B10, AKR1C3 |
2.36776 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.36776 |
|
[MF] GO:0005330 |
None
|
SLC6A2, SLC6A4 |
2.36776 |
|
[MF] GO:0047045 |
None
|
AKR1C3, HSD17B3 |
2.36776 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.36776 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.36776 |
|
[MF] GO:0004104 |
cholinesterase activity
|
ACHE, BCHE |
2.36776 |
|
[MF] GO:0047374 |
None
|
CES1, CES2 |
2.36776 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCG2, ADORA1, ADRA2A, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, MMP12, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RELA, RORC, SHBG, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, XDH |
2.28701 |
|
[MF] GO:0042166 |
None
|
ACHE, CHRNA3, CHRNA7 |
2.27896 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MAP2K1, MAP3K7, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.19887 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.15187 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.15187 |
|
[MF] GO:0015276 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, KCNH2 |
2.14013 |
|
[MF] GO:0022834 |
None
|
CHRNA3, CHRNA7, GRIA2, GRIA4, GRIK5, KCNH2 |
2.14013 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.1196 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.1196 |
|
[MF] GO:0032795 |
None
|
ADORA1, ADRA2A |
2.1196 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.1196 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.1196 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.1196 |
|
[MF] GO:0052689 |
carboxylic ester hydrolase activity
|
ACHE, BCHE, CA1, CA2, CES1, CES2 |
2.10181 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.09944 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, AR, BCL2, ESR1, ESRRB, FLT3, PIM1, PPARA, RELA, SMAD3, SRC, TERT |
2.07479 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, BCHE, CHRNA3, CHRNA7 |
2.02678 |
