GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.7828 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.7774 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FUT7, HSD17B3, PIM1, PPARA, PTGES, XDH |
10.8974 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES |
8.41986 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES |
7.99304 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES |
7.75322 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MMP9, PTGES, RELA, SRC |
7.54781 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALOX5, APP, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FABP4, FUT7, HSD17B3, MET, PPARA, PTGES |
7.49503 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, F3, FLT3, HCAR2, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
6.91945 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, F3, FLT3, HCAR2, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
6.90862 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES |
6.48761 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES |
6.40917 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PTGES |
6.39175 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CYP1B1, F10, F3, FLT3, KDR, MAP2K1, MAP3K7, MET, RELA, SRC, XDH |
6.34176 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, F3, FABP3, FABP4, FLT3, FUT7, HSD17B3, IGF1R, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP2, MMP9, PIM1, PPARA, PTGES, RELA, SRC, TOP1, XDH |
6.15072 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA |
6.02701 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.67522 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA12, CA2, CA7, CACNA1C, CYP19A1, CYP1A1, CYP1B1, F10, F3, FABP3, FABP4, FLT3, HCAR2, HSD17B3, KDR, MAOA, MET, PPARA, SRC, XDH |
5.46125 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.40666 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, FABP3, FABP4, FLT3, FUT7, HSD17B3, IGF1R, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP2, PIM1, PPARA, PTGES, RELA, SRC, TOP1, XDH |
5.33573 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA |
4.8454 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CYP1B1, F10, F3, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
4.77918 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CYP1B1, F3, FABP3, FLT3, IGF1R, KDR, MAP2K1, MMP2, MMP9, PIM1, PTGES, RELA, SRC, XDH |
4.76943 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FABP4, FUT7, MET, PPARA, PTGES |
4.76943 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CYP1B1, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MET, MMP9, PIM1, PPARA, RELA, SRC, XDH |
4.76943 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CYP1B1, F10, F3, FLT3, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
4.52561 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CYP1B1, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MET, MMP9, PIM1, RELA, SRC, XDH |
4.52251 |
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PTGES |
4.52251 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, APP, AR, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, IGF1R, KDR, MMP2, PPARA, PTGES, RELA, SRC |
4.2123 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CACNA1C, CYP19A1, CYP1B1, F10, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
4.1884 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CACNA1C, CYP19A1, CYP1B1, F10, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP9, RELA, SRC, XDH |
4.0989 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, IGF1R, MMP2, MMP9, PPARA, PTGES, RELA, SRC |
4.07822 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, APP, AR, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, PPARA, PTGES, RELA, SRC, TOP1 |
4.0737 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CYP1B1, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MMP9, PIM1, RELA, SRC, XDH |
3.90851 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, HSD17B3 |
3.84936 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CACNA1C, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B3, KDR, MAP2K1, PPARA, RELA, SRC |
3.76414 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, RELA, SRC |
3.71782 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CYP1B1, F10, F3, FABP4, FLT3, KDR, MAP2K1, MAP3K7, MET, MMP2, MMP9, RELA, SRC, XDH |
3.70664 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX15, APP, AR, AXL, CA2, CA7, CACNA1C, CYP19A1, CYP1B1, F10, F3, HCAR2, IGF1R, KDR, MAP2K1, MET, MMP9, PPARA, SRC |
3.67746 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, F10, F3, FABP3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP2, MMP9, PIM1, PPARA, RELA, SRC, XDH |
3.64661 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APP, CACNA1C, CYP19A1, CYP1B1, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
3.64661 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B3, MAOA, XDH |
3.64273 |
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.63736 |
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.63736 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MAP2K1, MET, SRC |
3.61427 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MAP2K1, MET, SRC |
3.57984 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
3.52857 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, FLT3, KDR, MAP2K1, MAP3K7, SRC, XDH |
3.47301 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, IGF1R, KDR, MET, MMP9, PIM1, PPARA, RELA, SRC |
3.4099 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, RELA, SRC |
3.38687 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
3.27511 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APP, AR, CA2, CA9, CYP1A2, FABP3, FLT3, IGF1R, MMP2, PPARA, RELA, SRC |
3.2704 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.18509 |
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, CA2, CYP1A1, CYP1A2, FABP4, MMP9, PTGES |
3.1823 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP2, MMP9, RELA, SRC |
3.17398 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, F10, F3, FABP3, FABP4, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP2, MMP9, PIM1, PPARA, RELA, SRC, XDH |
3.17398 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PIM1, PPARA, PTGES |
3.12723 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, IGF1R, KDR, MET, MMP9, PIM1, RELA, SRC |
3.08359 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA6, CA9, CYP1A1, CYP1A2, CYP1B1, F10, F3, FABP3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP2, MMP9, PPARA, PTGES, RELA, SRC, TOP1 |
3.08359 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, SRC, XDH |
3.08359 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA9, CACNA1C, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, FUT7, HSD17B3, KDR, MAP2K1, MET, MMP2, MMP9, PIM1, PPARA, RELA, SRC |
3.07849 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CA9, CYP1A1, CYP1A2, FABP3, FLT3, PTGES, RELA, SRC |
3.07632 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, APP, AR, AXL, CYP1A1, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, RELA, SRC |
3.06249 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APP, AR, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FLT3, PTGES, RELA, SRC |
3.05742 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, ALOX15, ALOX5, APP, AR, AXL, CACNA1C, CYP19A1, CYP1A2, CYP1B1, F10, F3, FABP4, IGF1R, MET, MMP1, MMP2, MMP9, PIM1, PPARA, RELA, SRC, TOP1 |
3.0246 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
3.01393 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, MAOA, MMP1, MMP2, MMP9, SRC, XDH |
2.97186 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, SRC, TOP1 |
2.80497 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PIM1, PPARA, PTGES |
2.76247 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, RELA, SRC |
2.75884 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, MAP3K7, PIM1, PPARA, RELA, SRC |
2.74896 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CACNA1C, CYP19A1, CYP1A1, CYP1B1, HCAR2, HSD17B3 |
2.7113 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PIM1, PPARA, PTGES |
2.70195 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AR, CA2, CA9, CYP1A2, FABP3, FLT3, PPARA, RELA, SRC |
2.65601 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, CA2, CYP1B1, F3, HCAR2, KDR, MAP2K1, MAP3K7, MET, MMP9, PIM1, RELA, SRC |
2.65601 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B3 |
2.63237 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, CYP1B1, RELA, SRC |
2.62929 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B3 |
2.62929 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AXL, CYP1B1, MMP9, RELA, SRC |
2.52732 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, FLT3, IGF1R, KDR, PIM1, SRC |
2.50606 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, ALOX15, APP, CYP19A1, CYP1A1, CYP1B1, HSD17B3, MAOA |
2.50318 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, HSD17B3, KDR, MAP2K1, MMP9, PIM1, PPARA, RELA, SRC |
2.49574 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, IGF1R, KDR, MMP9, PIM1, RELA, SRC |
2.48258 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, AXL, CYP1B1, KDR, RELA |
2.43848 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, MET, MMP9, PPARA, SRC |
2.42278 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, F10, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, SRC, TOP1 |
2.39827 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, CA2, CA7, CACNA1C, KDR, SRC |
2.39827 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.3964 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, AXL, CYP1B1, RELA |
2.37423 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, F10, F3, MET, SRC, XDH |
2.37403 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
2.34784 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, FABP3, KDR, MMP2, PTGES, RELA, SRC |
2.32798 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CA9, CYP1A1, CYP1B1, FABP3, KDR, RELA, SRC, TOP1 |
2.32579 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, F3, FABP4, IGF1R, MAP2K1, MAP3K7, MET, MMP2, PPARA, RELA, SRC, XDH |
2.30848 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
2.25175 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.25022 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CYP1B1, IGF1R, MMP2, MMP9, RELA, SRC |
2.25022 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, FABP3, FLT3, KDR, MAP2K1, MAP3K7, MMP9, SRC, XDH |
2.23806 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, FABP3, FLT3, KDR, MAP2K1, MAP3K7, MMP9, SRC, XDH |
2.23806 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.20395 |
[BP] GO:0006811 |
None
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, FABP3, PPARA |
2.20302 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP9, PPARA, SRC, XDH |
2.19917 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
2.19336 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APP, AXL, CYP1B1, MMP9, RELA, SRC |
2.19336 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, CACNA1C, HCAR2, KDR, SRC |
2.17252 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, FLT3, KDR, MAP2K1, MAP3K7, MMP9, SRC, XDH |
2.16617 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.16617 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.16617 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APP, FABP3, IGF1R, PPARA, RELA, SRC |
2.16439 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, FABP3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP9, PPARA, SRC, XDH |
2.1572 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, FABP3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP9, PPARA, SRC, XDH |
2.1199 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, F10, F3, IGF1R, KDR, MET, MMP9, SRC |
2.11447 |
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9 |
2.10488 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, SRC, TOP1 |
2.09698 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HCAR2, PPARA, SRC |
2.0745 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, MAP2K1, MAP3K7, MMP2, MMP9, PPARA, PTGES, RELA, SRC |
2.07231 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, F10, F3, MET, SRC |
2.06835 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, SRC |
2.06835 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APP, AXL, CA12, CA2, CA7, CACNA1C, FABP3, FABP4, FLT3, MET, SRC |
2.06835 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, IGF1R, KDR, MAP2K1, MET, MMP1, MMP9, SRC |
2.04866 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, FLT3, KDR, MAP2K1, MAP3K7, MMP9, SRC, XDH |
2.04079 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, CYP1A1, FLT3, MAP2K1, MET, PIM1, SRC |
2.03944 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MMP9, SRC, XDH |
2.01782 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CYP19A1, CYP1B1, F10, F3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP2, MMP9, PPARA, RELA, SRC, XDH |
2.01568 |
[BP] GO:0061370 |
testosterone biosynthetic process
|
CYP19A1, HSD17B3 |
2.0027 |
[BP] GO:0010641 |
None
|
F3, SRC |
2.0027 |
[BP] GO:0007598 |
None
|
F10, F3 |
2.0027 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.47301 |
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.39827 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX15, ALOX5, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, F3, FLT3, FUT7, HCAR2, HSD17B3, IGF1R, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP2, PIM1, PTGES, SRC |
2.06835 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, ALOX15, ALOX5, APP, AR, AURKB, CA1, CA2, CA4, CA5A, CA5B, CA7, CACNA1C, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, FABP3, FABP4, FLT3, FUT7, HSD17B3, KDR, MAOA, MAP2K1, MAP3K7, MMP2, MMP9, PIM1, PTGES, RELA, SRC, TOP1, XDH |
1.93585 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALOX15, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, F10, F3, FLT3, HCAR2, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP2, PIM1, SRC |
1.90453 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
18.1973 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MMP1, MMP2, MMP9, PIM1, PPARA, XDH |
13.1768 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.846 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.6543 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, F3, FABP3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP2, MMP9, PIM1, PPARA, PTGES, RELA, SRC, TOP1, XDH |
10.3103 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, ALOX15, ALOX5, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, F3, FLT3, FUT7, HSD17B3, IGF1R, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP2, MMP9, PIM1, PTGES, SRC, TOP1, XDH |
9.96647 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
7.01976 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
7.01905 |
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, XDH |
6.34176 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
5.47499 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, MAP3K7, MMP1, MMP2, MMP9, PIM1, PPARA, XDH |
5.27108 |
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, MAP3K7, MMP1, MMP2, MMP9, PIM1, PPARA, XDH |
4.83733 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, MMP1, MMP2, MMP9, PPARA |
4.78652 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC |
4.52251 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B3, MAOA, XDH |
4.51715 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC |
4.32533 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.17551 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.00817 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, PPARA, SRC, TOP1 |
3.8135 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MAP2K1, MET, SRC |
3.65102 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.61427 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, SRC, TOP1 |
3.4099 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
3.19973 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.17398 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
3.01393 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES, SRC, XDH |
2.86326 |
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.77585 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, SRC, TOP1 |
2.77194 |
[MF] GO:0043168 |
anion binding
|
ALOX15, APP, AURKB, AXL, F10, F3, FABP3, FABP4, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, PTGES, RELA, SRC, TOP1, XDH |
2.48258 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, FLT3, IGF1R, KDR, MAP2K1, MAP3K7, MET, PIM1, SRC, TOP1 |
2.48014 |
[MF] GO:0005497 |
None
|
AR, SHBG |
2.16617 |