| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
15.641 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, F10, FABP3, FABP4, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TRPV1, XDH |
14.9718 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, GPER1, GRIK5, GRM5, HSD17B2, HSP90AB1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
14.9718 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
13.0687 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FLT3, GPER1, HSP90AB1, NR3C1, PPARG, PRKCE, PRKCG, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
11.9634 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GPER1, GRIK5, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.9634 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GPER1, GRIK5, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.7727 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, HSP90AB1, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
11.5737 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
11.5534 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, GRM5, IGF1R, INSR, MMP2, NR3C1, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
11.5476 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GPER1, GRIK5, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
11.4314 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, INSR, NR3C1, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
11.1901 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, FLT3, GPER1, GPR35, GRM1, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.0805 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, FLT3, GPER1, GPR35, GRM1, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.046 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.6267 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.6237 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, EGFR, F10, FLT3, GPER1, GPR35, GRM1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.089 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CYP1B1, EGFR, ESR1, GPER1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
10.069 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, SRC |
9.8757 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.8757 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, FABP3, FABP4, FUT7, HSD11B1, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PPARG, PTGS1, PTGS2, TRPV1 |
9.56984 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.53288 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, F10, FLT3, GPER1, GPR35, GRM1, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.32669 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, F10, FLT3, GPER1, GPR35, GRM1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.30852 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HSP90AB1, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.16477 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.16141 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PPARG, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
9.13507 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HSP90AB1, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.10492 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HSP90AA1, HSP90AB1, INSR, MET, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCE, SMAD3, SRC, TRPV1 |
9.10492 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.03854 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.03854 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.02289 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.92571 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD17B2, NR3C1, PPARG, PRKCE, PTGS2, RORC, SRC, TYR |
8.91319 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.91319 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, GPER1, HSP90AB1, NR3C1, PPARG, PTGS2, RORC, SRC, TRPV1 |
8.73943 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, SRC |
8.71414 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.63513 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, GPER1, GPR35, GRIK5, GRM5, HCAR2, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
8.60132 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, PPARG, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.60132 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ESRRB, FLT3, GPER1, GRM1, GRM5, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.60132 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESRRA, F10, FABP4, FLT3, GPER1, GPR35, GRM1, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.57958 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PGR, PIM1, PPARA, PPARG, RORC, SRC |
8.51846 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
8.36963 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSP90AB1, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.35629 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, FLT3, GPER1, GRM1, GRM5, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.25401 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FUT7, GLO1, HSPA1A, PIK3CA, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR, XDH |
8.11116 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, BCL2, CDC25B, CSNK2A1, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PGR, PIM1, PPARG, PRKCA, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
7.97239 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
7.86992 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, F10, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR |
7.86162 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, EGFR, FABP3, FLT3, GPER1, GRM5, HSP90AB1, IGF1R, INSR, MMP2, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
7.74783 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.67878 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, EGFR, GPER1, GRIK5, HSP90AA1, HSP90AB1, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.66603 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.64162 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, GPER1, GPR35, GRIK5, GRM1, GRM5, INSR, MET, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCE, SMAD3, TRPV1 |
7.54821 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP4, FLT3, GPER1, GRM1, GRM5, HSP90AB1, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.52367 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TRPV1 |
7.4536 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
7.39349 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TOP2A, TYR, XDH |
7.34619 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
7.29666 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, XDH |
7.27133 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, EGFR, FABP3, FLT3, GPER1, GRM5, HSP90AB1, IGF1R, INSR, MMP2, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
7.19404 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.19284 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.1841 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, MMP9, PRKCD, PTGS2, SRC |
7.12933 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, PIK3CA, PPARA, PPARG, SMAD3, SRC, TEK, TYR |
7.07348 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, GPER1, GRM1, GRM5, HSP90AB1, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.07348 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
7.04008 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, EGFR, ESR1, FLT3, GPER1, GRM5, IGF1R, INSR, MMP2, NR3C1, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
7.03512 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GPER1, GRM5, IGF1R, INSR, PPARA, PPARG, PRKCD, PTGS2, SRC, TEK, TRPV1 |
6.99116 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CSNK2A1, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, RORC, SMAD3, SRC, TEK, TRPV1 |
6.96532 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, PPARG, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
6.9588 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.94656 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, FLT3, GPER1, GRM1, GRM5, HSP90AB1, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.8606 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCE, PTGS2 |
6.86 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCE, PTGS2 |
6.86 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.83119 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, FLT3, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
6.79296 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ESR1, FLT3, GPER1, GRM1, GRM5, HSP90AB1, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.78123 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC |
6.76831 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CYP19A1, EGFR, GPER1, GPR35, GRIK5, GRM5, HCAR2, HSP90AB1, HSPA1A, INSR, MMP9, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
6.75675 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DUSP3, EGFR, FLT3, GPER1, GRM1, IGF1R, INSR, KDR, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
6.71929 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, FABP4, FLT3, GPER1, GPR35, GRM1, GRM3, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1, XDH |
6.66009 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
6.66009 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.64027 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.62479 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.59233 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, EGFR, FLT3, GPER1, GRM1, INSR, KDR, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
6.57778 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, HSP90AA1, HSP90AB1, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
6.55842 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
6.48519 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
6.48519 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, EGFR, GRM1, HSP90AA1, HSP90AB1, HSPA1A, MMP2, PPARA, PPARG, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
6.46085 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
6.41215 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.39985 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, FLT3, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
6.36097 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, FLT3, GPER1, GRM1, GRM5, HSP90AB1, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.32547 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSP90AB1, KDR, NR3C1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
6.28259 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.24692 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, APP, AR, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, INSR, MET, MMP9, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, XDH |
6.21952 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
6.179 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.17805 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
6.12959 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.11159 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.07127 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, EGFR, F10, GPER1, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.05738 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, DUSP3, EGFR, ESR1, FABP4, GPER1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, MET, MMP2, NUAK1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.01038 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.9847 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
5.96445 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, GPER1, HCAR2, PPARA, PPARG, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
5.96445 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, HSD11B1, HSD17B1, HSD17B2 |
5.96445 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
5.96445 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD11B1, HSD17B1, HSD17B2, NQO2, PPARG, PTGS1, PTGS2, TYR, XDH |
5.95194 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
5.94495 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA9, CYP1A1, CYP1B1, EGFR, FABP3, HSP90AB1, KDR, NR3C1, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
5.87331 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
5.84018 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, GPER1, HCAR2, HSD11B1, HSD17B1, HSD17B2, PRKCA, PRKCE, SLC22A1 |
5.83526 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
5.83101 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HCAR2, HSP90AB1, HSPA1A, IGF1R, KDR, MET, MMP9, NR3C1, PGR, PIK3CA, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
5.81827 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.81651 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC |
5.7973 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, FLT3, GPER1, GPR35, GRM1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.71536 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, FABP4, FLT3, GPER1, GPR35, GRM1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.69498 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, F10, GPER1, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
5.67851 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PPARG, PRKCD, PRKCE, PTGS2, SRC, TEK |
5.61481 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
5.57238 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GPER1, GRM5, IGF1R, INSR, MMP2, PPARG, PRKCD, PTGS2, SRC, TRPV1 |
5.55636 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
5.47573 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, FABP3, FABP4, FUT7, MET, PIK3CA, PIK3CB, PPARA, PPARG, PTGS1, PTGS2 |
5.45297 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, F10, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A |
5.42447 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.39015 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, PGR, PPARA, PPARG, PRKCG, RORC, SRC, TOP2A |
5.36221 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRB, F10, FABP4, GPER1, GRM1, GRM5, GRM8, HSD17B2, IGF1R, INSR, MET, MMP1, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
5.35075 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, MMP2, PPARA, PPARG, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.2541 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
5.23985 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, FABP4, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.23768 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, MET, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A, TYR |
5.23435 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, GPER1, HSP90AA1, HSP90AB1, HSPA1A, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARG, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
5.21775 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PPARG, PTGS1, PTGS2 |
5.19232 |
|
[BP] GO:0006811 |
None
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, GRIA2, GRIA4, GRIK5, PPARA, PPARG, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
5.17534 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GPER1, GRM5, IGF1R, INSR, MMP2, PPARG, PRKCD, PTGS2, SRC, TRPV1 |
5.17296 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
5.16814 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HSP90AA1, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PPARG, PRKCD, PTPN1, SRC, TEK |
5.12056 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CYP19A1, DUSP3, ESR1, ESRRA, GPER1, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, MMP2, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
5.10608 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, INSR, PIK3CA, PIK3CB, PPARG, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, XDH |
5.10507 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.08867 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.05756 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, GPER1, HSP90AB1, INSR, PRKCA, PRKCE, SRC |
5.04781 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
5.01581 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.99104 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSP90AB1, INSR, PGR, PPARG, PTGS2, SRC |
4.95721 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.93392 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.91623 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
4.90712 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
4.86846 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2 |
4.84305 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.8397 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GPER1, HSP90AB1, HSPA1A, MMP2, PPARA, PPARG, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.79926 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GPR35, GRM3, IGF1R, MET, MMP9, PIM1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC |
4.79668 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GPER1, GRM5, IGF1R, INSR, PPARG, PRKCD, SRC |
4.79414 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, HSP90AB1, NQO2, PTGS1, RORC |
4.77709 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
4.7546 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, GPER1, PPARA, PPARG, PRKCD, SMAD3, TEK |
4.75183 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, PGR, SRC |
4.72738 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.71796 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, EGFR, GPER1, HCAR2, KDR, PIK3CB, PRKCE, PTGS2, SRC, TRPV1 |
4.68651 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PPARG, PRKCE, SRC |
4.62592 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, GPER1, NR3C1, PTGS2, SRC |
4.61083 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.60519 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, INSR, PPARA, PPARG, PRKCD, PTGS2, SRC, TEK, TRPV1 |
4.60519 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, EGFR, GPER1, PRKCE, PTGS2 |
4.60519 |
|
[BP] GO:1903426 |
None
|
EGFR, HSP90AA1, HSP90AB1, INSR, PTGS2, SMAD3, TRPV1 |
4.60093 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, NR3C1, PPARG, PRKCD, PRKCE, SRC |
4.59229 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, BCL2, CA2, CYP1B1, EGFR, ESRRB, GPER1, HCAR2, HSPA1A, KDR, MET, MMP9, PIM1, PPARG, PRKCA, PRKCB, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
4.54691 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AR, AXL, BCL2, CA2, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, GPER1, GPR35, GRM1, HCAR2, HSP90AB1, HSPA1A, INSR, KDR, MET, MMP9, PIK3CA, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1, XDH |
4.53219 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.52533 |
|
[BP] GO:0010676 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, SRC |
4.52316 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPER1, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.52173 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.51181 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.47407 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, FABP4, FLT3, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.39962 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PPARG, PRKCE, SRC |
4.39445 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.37391 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, NR3C1, PGR, PPARA, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
4.33891 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.28482 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD17B1, HSD17B2 |
4.26972 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, FLT3, GRM1, GRM5, HSP90AA1, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.26972 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, EGFR, GPER1, HCAR2, HSP90AB1, INSR, PPARG, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
4.25031 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSP90AB1, INSR, KDR, MMP9, PGR, PIK3CA, PIM1, PPARA, PPARG, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
4.25031 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, AR, BCL2, CYP19A1, DUSP3, EGFR, ESR1, ESR2, GPER1, HSPA1A, IGF1R, MET, MMP9, PPARA, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.24932 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
4.24588 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CSNK2A1, DUSP3, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HSP90AB1, HSPA1A, IGF1R, MET, MMP9, NR3C1, PIK3CA, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
4.2429 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DUSP3, EGFR, GPER1, HSP90AA1, HSP90AB1, HSPA1A, INSR, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TOP2A |
4.24009 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, NR3C1, PGR, PPARA, PPARG, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TOP2A |
4.22056 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, GPER1, GRIK5, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.21953 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, ESR1, GPER1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PPARG, PRKCD, PRKCE, SMAD3, SRC, TEK |
4.21564 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.21564 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, ESR1, GPER1, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.18967 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, DUSP3, EGFR, ESR1, ESR2, GPER1, GPR35, HSPA1A, IGF1R, MET, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
4.18335 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, GPER1, GRIK5, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.17639 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HSP90AB1, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.17202 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.16948 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, DUSP3, EGFR, ESR1, ESR2, GPER1, GPR35, HSPA1A, IGF1R, MET, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
4.16751 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, FLT3, GPER1, IGF1R, INSR, KDR, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK |
4.16267 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
4.13355 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HSP90AB1, HSPA1A, IGF1R, MMP9, NR3C1, PPARA, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
4.10973 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, GPER1, HSP90AA1, HSP90AB1, IGF1R, INSR, PIK3CA, PPARG, PRKCD, PRKCG, SRC |
4.10137 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GPER1, PPARA, PPARG, PRKCD, PTGS2, SMAD3, TEK |
4.10137 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.0654 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, GLO1, GPER1, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.05885 |
|
[BP] GO:0006855 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.05453 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.0512 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, EGFR, FLT3, GRM1, GRM5, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.04919 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.99701 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HSP90AA1, HSP90AB1, IGF1R, INSR, MET, NR3C1, PGR, PPARA, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
3.9911 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, HSP90AB1, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
3.98436 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
3.97904 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, HSP90AB1, MET, MMP9, PPARA, PRKCD, SRC |
3.95959 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, HSP90AA1, KDR, PRKCD, PRKCE, SRC |
3.95959 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PPARA, PPARG, PTGS1, PTGS2 |
3.95361 |
|
[BP] GO:0045913 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, SRC |
3.91804 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, GPER1, KDR, PRKCE, SRC, TRPV1 |
3.91704 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSP90AB1, INSR, PPARG, SRC |
3.90022 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GPER1, NR3C1, PTGS2, SRC |
3.90022 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.90022 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.90022 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.90022 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
3.8847 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
3.86546 |
|
[BP] GO:0038128 |
None
|
EGFR, HSP90AA1, PIK3CA, PRKCA, SRC |
3.86011 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DUSP3, EGFR, GPER1, KDR, PRKCA, PTPN1, SRC, TEK |
3.85316 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DUSP3, EGFR, HSP90AA1, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TOP2A |
3.85274 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD17B2, HSP90AB1, INSR, MMP2, MMP9, PGR, PPARG, PTGS2, SRC, TOP2A |
3.85274 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, HSP90AA1, HSP90AB1, IGF1R, INSR, PRKCD, PRKCG, SRC |
3.85271 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, GPER1, GRIK5, HCAR2, MMP9, PIK3CB, PPARG, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.84027 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, HSP90AB1, MET, MMP9, PPARA, PPARG, PRKCD, SMAD3, SRC |
3.84027 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PPARG, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.8236 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, ESR1, ESR2, GPER1, GRIK5, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PPARG, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
3.8174 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, HSP90AA1, KDR, PIK3CA, PIK3CB, SRC |
3.80196 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.80122 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
3.78555 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.76718 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.73736 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
3.72812 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, EGFR, ESR1, FLT3, GPER1, NR3C1, PPARG, PRKCE, RORC, SRC |
3.70016 |
|
[BP] GO:0007154 |
None
|
ADORA1, AR, AXL, BCL2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PGR, PPARG, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
3.68988 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, PRKCD, SRC, TEK |
3.67423 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, EGFR, FLT3, GRM1, GRM5, HSP90AB1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.66764 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.64689 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, ESR1, GPER1, HSPA1A, IGF1R, MET, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
3.64279 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.63359 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GPER1, KDR, MET, PPARA, PPARG, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
3.63123 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, GPER1, PPARA, PPARG, PRKCD, SMAD3, TEK |
3.62918 |
|
[BP] GO:0010675 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, RORC, SRC |
3.61501 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, PRKCD, PRKCE, PTPN1, SRC |
3.60004 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PPARG, PTGS2, TYR |
3.50296 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.4994 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, PPARA, SMAD3 |
3.4941 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.49056 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.49056 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, MMP2, MMP9, PPARG, PTGS2 |
3.46743 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
3.449 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
3.44564 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, HSP90AB1, PRKCD, PTGS2, SMAD3, SRC |
3.42937 |
|
[BP] GO:0038096 |
Fc-gamma receptor signaling pathway involved in phagocytosis
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.42937 |
|
[BP] GO:0002433 |
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.42937 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.42376 |
|
[BP] GO:0051972 |
regulation of telomerase activity
|
AURKB, HSP90AA1, HSP90AB1, PPARG, SRC |
3.42376 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
3.4214 |
|
[BP] GO:0002431 |
Fc receptor mediated stimulatory signaling pathway
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.39197 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGS1, PTGS2 |
3.36304 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.3578 |
|
[BP] GO:0038094 |
Fc-gamma receptor signaling pathway
|
HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCD, PRKCE, SRC |
3.35395 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.34877 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.34321 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PPARG, PRKCE, PTGS2, SRC |
3.31135 |
|
[BP] GO:0050994 |
None
|
ADORA1, HCAR2, PPARA, PRKCD, PRKCE |
3.31129 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, EGFR, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, MET, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, XDH |
3.30728 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, ESR1, GPER1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.23673 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, EGFR, GPER1, KDR, PRKCA, SRC, TEK |
3.22644 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.2199 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.18097 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, PRKCA |
3.17446 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PPARG, PTGS2, TEK, TRPV1, TYR |
3.14006 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DUSP3, EGFR, ESR1, ESR2, GPER1, HSPA1A, IGF1R, MET, MMP9, PPARG, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.12674 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, GPER1, GRM5, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
3.1255 |
|
[BP] GO:0042307 |
positive regulation of protein import into nucleus
|
APP, EGFR, HSP90AB1, PRKCD, PTGS2, SMAD3 |
3.11383 |
|
[BP] GO:0042752 |
None
|
ADORA1, PPARA, PPARG, PRKCG, RORC, TOP2A |
3.11383 |
|
[BP] GO:0015893 |
None
|
CA2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.10851 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.10851 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, GPER1, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
3.10792 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, PRKCA, PRKCB, PRKCD |
3.10792 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HSP90AB1, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
3.1045 |
|
[BP] GO:0008217 |
None
|
ADORA1, AR, PPARA, PPARG, PTGS1, PTGS2, SMAD3 |
3.09405 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, NR3C1, PGR, PPARA, PPARG, RORC, SMAD3, SRC, TOP2A |
3.07339 |
|
[BP] GO:1904591 |
positive regulation of protein import
|
APP, EGFR, HSP90AB1, PRKCD, PTGS2, SMAD3 |
3.07264 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, ESRRB, HSP90AB1, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
3.05909 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, GRM5 |
3.02704 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.02704 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, HSP90AB1, HSPA1A, IGF1R, KDR, MMP9, NR3C1, PGR, PPARA, PPARG, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TRPV1, XDH |
3.01265 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, EGFR, GPER1, HCAR2, HSP90AB1, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.01198 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
3.01114 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD17B1, HSD17B2 |
3.01114 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
3.00814 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.99944 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.98892 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, EGFR, GPER1, GPR35, GRM1, HCAR2, PRKCA, PTGS2, SLC1A1, SMAD3, TRPV1 |
2.98574 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, AR, BCL2, CSNK2A1, EGFR, GPER1, HSP90AB1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.98574 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
2.9649 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.94896 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, PIK3CB, PPARG, PRKCG, PTPN1, SRC |
2.94043 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, GPER1, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK |
2.93283 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.90907 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, PRKCE |
2.89932 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, EGFR, GPER1, HCAR2, HSP90AB1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.89932 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, EGFR, GPER1, HSP90AA1, HSP90AB1, HSPA1A, INSR, PRKCE |
2.8717 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, DUSP3, ESR1, HSP90AA1, HSP90AB1, HSPA1A, MMP2, PIK3CA, PIK3CB, PPARG, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
2.87044 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
2.85646 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, EGFR, GPER1, HCAR2, PIK3CB, PTGS2 |
2.85426 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.85217 |
|
[BP] GO:0006810 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, F10, FABP3, GRIA2, GRIA4, GRIK5, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
2.84521 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.84521 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.84521 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.84474 |
|
[BP] GO:0051234 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
2.82439 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.80985 |
|
[BP] GO:0015872 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.80985 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CYP1B1, ESRRB, GPER1, HSP90AB1, INSR, KDR, PIM1, PPARG, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK |
2.80274 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.78967 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GPER1, GRM3, GRM8, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, NR3C1, NR3C2, PGR, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
2.77187 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC |
2.76926 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUT7, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PRKCB, PRKCD, PRKCE, RORC, SMAD3, TRPV1 |
2.74977 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.74658 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, GPER1, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
2.74335 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
2.74335 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GPER1, INSR, PPARA, PRKCE, RORC, SRC |
2.71754 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, AR, CYP1B1, ESR1, ESR2, HSPA1A, PIM1, PPARG, PRKCB |
2.7106 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, PRKCD, SRC, TEK |
2.7106 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.7106 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.7106 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, GPER1, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.70662 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, PTGS1, PTGS2 |
2.68176 |
|
[BP] GO:0032409 |
None
|
APP, BCL2, GPR35, GRM5, MMP9, PPARG, PRKCD, PRKCE |
2.67623 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.67623 |
|
[BP] GO:0034097 |
response to cytokine
|
ALOX15, AXL, BCL2, FABP4, FLT3, GPER1, HSP90AB1, PRKCA, PTGS2, SRC, TRPV1 |
2.66314 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
2.66067 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GLO1, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TYR, XDH |
2.64943 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.64352 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.64344 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, EGFR, GPER1, HCAR2, HSP90AB1, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.64344 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.62018 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, GPER1, PTGS2 |
2.61608 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, EGFR, GPER1, HSP90AB1, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.61489 |
|
[BP] GO:0007193 |
None
|
ADORA1, GRM1, GRM3, GRM5, GRM8 |
2.61489 |
|
[BP] GO:0031100 |
animal organ regeneration
|
AXL, CSNK2A1, EGFR, FLT3, PPARG |
2.61489 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTGS2 |
2.61489 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.60965 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD |
2.56247 |
|
[BP] GO:0051179 |
None
|
ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HSP90AA1, HSP90AB1, HSPA1A, MMP9, PPARA, PPARG, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TRPV1, XDH |
2.55384 |
|
[BP] GO:0051937 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.53349 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, GPER1, HSP90AB1, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PPARG, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, XDH |
2.53021 |
|
[BP] GO:0050678 |
None
|
AR, EGFR, KDR, PGR, PPARG, PRKCA, SMAD3, TEK, XDH |
2.52784 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.52458 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, GPER1, KDR, PPARG, PRKCA, PRKCB, PTGS2, TEK, XDH |
2.52055 |
|
[BP] GO:1903076 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.51901 |
|
[BP] GO:0070542 |
None
|
FABP3, PPARG, PRKCE, PTGS2, SRC |
2.51901 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.51748 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, PPARG, RORC |
2.47139 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ADORA1, CA2, CA7, GRM5, PRKCD |
2.4704 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, PPARG, PTGS2, TRPV1, TYR |
2.46891 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.46067 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.46067 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.46067 |
|
[BP] GO:0051131 |
None
|
HSP90AA1, HSP90AB1, HSPA1A |
2.46067 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.46067 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, SRC |
2.45791 |
|
[BP] GO:0038127 |
None
|
EGFR, HSP90AA1, PIK3CA, PRKCA, SRC |
2.45251 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, PIK3CB, PTPN1, SRC |
2.44588 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.43904 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.43904 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.43904 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.43904 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, MET, NR3C1, NR3C2, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TOP2A, TRPV1 |
2.43795 |
|
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, EGFR, FLT3, PPARG |
2.43121 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCL2, CYP1B1, FABP3, GPER1, HSPA1A, PPARG, PTGS2, SMAD3, XDH |
2.43121 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD |
2.41998 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.41998 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, GPER1, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTGS2 |
2.41716 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.40011 |
|
[BP] GO:0042058 |
None
|
ADORA1, APP, EGFR, GPER1, MMP9 |
2.4001 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, NR3C1, PTGS2 |
2.38828 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, PPARG, PTGS2, SRC, TRPV1, TYR |
2.38612 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CSNK2A1, EGFR, GPER1, HCAR2, HSP90AB1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.38472 |
|
[BP] GO:0051248 |
None
|
APP, CSNK2A1, DUSP3, EGFR, FABP4, GPER1, HSP90AB1, HSPA1A, IGF1R, MMP9, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.36998 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HSP90AB1, INSR, PIK3CB, PTPN1, SRC |
2.36699 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, GPER1, PIK3CA, PIK3CB, PTGS1, PTGS2, TRPV1 |
2.36566 |
|
[BP] GO:1904375 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.3617 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, GPR35, MMP9, PRKCE, PTGS2 |
2.3617 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.334 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.334 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, EGFR, GPER1, HCAR2, HSP90AB1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.334 |
|
[BP] GO:0007267 |
None
|
ADORA1, AR, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PGR, PRKCG, SLC1A1, TEK |
2.31587 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, GPER1, PPARA, PPARG, PRKCD, SMAD3, TEK |
2.31578 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.31578 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
2.31391 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
2.31391 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
2.31309 |
|
[BP] GO:0043279 |
None
|
HSP90AB1, PPARG, PRKCE, PRKCG, TRPV1 |
2.30372 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, HSPA1A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.29813 |
|
[BP] GO:0009410 |
None
|
EGFR, HSP90AB1, NR3C1, PPARG, PRKCE, PRKCG |
2.29093 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, HSPA1A, MMP9, NUAK1, PPARG, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TOP2A, TRPV1 |
2.28052 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.27856 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.27856 |
|
[BP] GO:0035306 |
None
|
ADORA1, HSP90AB1, PRKCD, SMAD3 |
2.27856 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.27799 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, EGFR, GRM1, GRM5, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
2.27485 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ESR1, GPER1, GPR35, GRM1, GRM5, PRKCE, SMAD3, TRPV1 |
2.26764 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
2.26184 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HSP90AA1, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TOP2A |
2.24815 |
|
[BP] GO:0009266 |
None
|
ADORA1, HSP90AA1, HSPA1A, PPARG, PTGS2, TRPV1 |
2.23874 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.20937 |
|
[BP] GO:1905475 |
None
|
AR, BCL2, CSNK2A1, EGFR, GPER1, PRKCE |
2.19475 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, GPER1, KDR, TEK |
2.19475 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HSPA1A, NR3C1, PPARA, PPARG, PRKCA, RORC, SMAD3, SRC, TRPV1 |
2.19475 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.19475 |
|
[BP] GO:1905323 |
None
|
HSP90AA1, HSP90AB1 |
2.19475 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.19475 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.19475 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.19475 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.19475 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARG, PTGS1, PTGS2, TYR |
2.19178 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.19046 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, PPARG, SMAD3 |
2.18014 |
|
[BP] GO:1900180 |
regulation of protein localization to nucleus
|
APP, EGFR, HSP90AB1, PRKCD, PTGS2, SMAD3, SRC |
2.18014 |
|
[BP] GO:0003018 |
None
|
ADORA1, EGFR, GPER1, PTGS2, SRC, TEK |
2.17746 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.16812 |
|
[BP] GO:0015844 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.16812 |
|
[BP] GO:0007188 |
None
|
ADORA1, GPER1, GRM1, GRM3, GRM5, GRM8 |
2.16593 |
|
[BP] GO:0010594 |
regulation of endothelial cell migration
|
KDR, MET, PPARG, PRKCA, PTGS2, TEK |
2.16593 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, PIK3CA, PTGS2 |
2.16593 |
|
[BP] GO:1901184 |
None
|
ADORA1, APP, EGFR, GPER1, MMP9 |
2.16593 |
|
[BP] GO:0002429 |
immune response-activating cell surface receptor signaling pathway
|
BCL2, HSP90AA1, HSP90AB1, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, SRC |
2.15669 |
|
[BP] GO:0000904 |
cell morphogenesis involved in differentiation
|
AR, AXL, MET, SRC, TEK |
2.14698 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.14622 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.14622 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, EGFR, GPER1, HCAR2, PRKCE, SRC, TRPV1 |
2.14273 |
|
[BP] GO:0031334 |
positive regulation of protein complex assembly
|
ALOX15, ESR1, HSPA1A, MET, MMP1, PRKCE, SRC |
2.14217 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.14206 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.13348 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.13348 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.13348 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.13348 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.1189 |
|
[BP] GO:0050996 |
None
|
PPARA, PRKCD, PRKCE |
2.1189 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.11568 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.09065 |
|
[BP] GO:0071375 |
None
|
APEX1, GPER1, INSR, PPARG, PRKCD, SRC |
2.09065 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AR, AXL, BCL2, CDC25B, CYP1A1, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GLO1, KDR, MET, MMP2, MMP9, PGR, PPARG, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.08528 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CSNK2A1, EGFR, GPER1, GRIK5, HSP90AB1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.07991 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.06693 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.06693 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.06693 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, HSP90AA1, HSPA1A, MMP1, MMP2, MMP9, PIK3CB, SRC, XDH |
2.06693 |
|
[BP] GO:2000278 |
regulation of DNA biosynthetic process
|
AURKB, HSP90AA1, HSP90AB1, PPARG, SRC |
2.06424 |
|
[BP] GO:0043254 |
regulation of protein complex assembly
|
ALOX15, ESR1, HSP90AA1, HSPA1A, MET, MMP1, PRKCD, PRKCE, SRC |
2.05868 |
|
[BP] GO:1900542 |
None
|
ESRRB, GPER1, GRM3, GRM8, INSR, PPARA, PRKCA |
2.05357 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, EGFR, GPER1, HCAR2, HSP90AB1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.05152 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, KDR, PRKCE, SMAD3, TEK |
2.04869 |
|
[BP] GO:0051254 |
None
|
APP, AR, EGFR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, INSR, MET, NR3C1, PGR, PPARA, PPARG, RORC, SMAD3, SRC, TOP2A |
2.03124 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.03115 |
|
[BP] GO:0052548 |
None
|
APP, CSNK2A1, GPER1, MMP9, PPARG, PTGS2, SMAD3, SRC, XDH |
2.02263 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.02098 |
|
[BP] GO:0035902 |
response to immobilization stress
|
CYP1A1, CYP1A2, PPARG |
2.02098 |
|
[BP] GO:0061900 |
None
|
APP, EGFR, TRPV1 |
2.02098 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.02098 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, F10, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
2.01891 |
|
[BP] GO:0046618 |
None
|
SLC47A1, SLC47A2 |
2.01502 |
|
[BP] GO:0032800 |
receptor biosynthetic process
|
ACHE, PPARG |
2.01502 |
|
[BP] GO:0030263 |
None
|
GPER1, TOP2A |
2.01502 |
|
[BP] GO:0010891 |
None
|
PPARA, PPARG |
2.01502 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
2.00059 |
|
[BP] GO:0071384 |
None
|
EGFR, FLT3, GPER1, NR3C1 |
2.00059 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, EGFR, ESR1, F10, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSP90AA1, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1 |
7.93486 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, CA2, CA4, CA9, EGFR, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, INSR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
7.27416 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, F10, FLT3, FUT7, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD17B2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1, TYR |
6.32219 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ALOX15, APP, AXL, CA2, CA4, CA9, DUSP3, EGFR, F10, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
5.30516 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD17B2, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MET, MPEG1, NR3C2, PIK3CA, PIK3CB, PRKCG, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TEK, TRPV1, TYR |
4.71796 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, CA4, F10, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
4.33735 |
|
[CC] GO:0042734 |
None
|
GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
4.12564 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, HSP90AB1, IGF1R, INSR, NR3C2, SMAD3 |
4.05885 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, GPER1, HSPA1A, PPARG, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TYR |
3.93545 |
|
[CC] GO:0097060 |
None
|
GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, TRPV1 |
3.6989 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
3.63236 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SLC22A2, SRC, TRPV1 |
3.60718 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, HSP90AB1, SLC22A1, TEK |
3.3894 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, FLT3, GPER1, GRIK5, HSPA1A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, XDH |
3.28237 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GRIA2, GRIA4, GRIK5, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TOP2A, TRPV1, TYR, XDH |
3.23673 |
|
[CC] GO:0014069 |
None
|
ADORA1, GPER1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
3.2152 |
|
[CC] GO:0099572 |
None
|
ADORA1, GPER1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
3.2152 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, F10, FLT3, GPER1, GRIA2, HSD11B1, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1 |
2.68702 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, GPER1, HSP90AA1, HSP90AB1, INSR, SRC, TRPV1 |
2.66651 |
|
[CC] GO:0032589 |
None
|
ADORA1, GPER1, INSR, TRPV1 |
2.52458 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GLO1, GPER1, GRIA4, GRIK5, GRM1, GRM5, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TOP2A, TYR, XDH |
2.41142 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, GPER1, GRIA2, HSD11B1, HSD17B2, NR3C2, PTGS1, PTGS2 |
2.38612 |
|
[CC] GO:1903561 |
None
|
AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, DUSP3, FABP3, FABP4, GLO1, GRIA4, GRM5, HSP90AA1, HSP90AB1, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, SHBG, SLC1A1, SLC22A2, SRC |
2.32696 |
|
[CC] GO:0043230 |
None
|
AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, DUSP3, FABP3, FABP4, GLO1, GRIA4, GRM5, HSP90AA1, HSP90AB1, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, SHBG, SLC1A1, SLC22A2, SRC |
2.32569 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, GPER1, GRIA2, GRIA4, GRIK5, GRM3, HSP90AA1, HSP90AB1, INSR, PTGS1, SRC, TRPV1 |
2.27485 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, GPER1, GRIA2, GRIA4, GRIK5, GRM3, HSP90AA1, HSP90AB1, INSR, PTGS1, SRC, TRPV1 |
2.27485 |
|
[CC] GO:0031256 |
None
|
ADORA1, GPER1, HSP90AA1, INSR, SRC, TRPV1 |
2.22377 |
|
[CC] GO:0005654 |
None
|
AKR1B1, ALOX5, APEX1, AR, AURKB, BCL2, CDC25B, CSNK2A1, DUSP3, ESR1, ESR2, ESRRA, ESRRB, HSP90AA1, HSP90AB1, HSPA1A, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, RORC, SMAD3, SRC, TOP2A |
2.19107 |
|
[CC] GO:0031982 |
None
|
AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, DUSP3, EGFR, FABP3, FABP4, GLO1, GPER1, GRIA4, GRM5, HSP90AA1, HSP90AB1, HSPA1A, INSR, KDR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPN1, SHBG, SLC1A1, SLC22A2, SLC47A1, SRC, TYR |
2.10216 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, CA2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, SRC |
2.00518 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TYR, XDH |
22.3392 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.641 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR, XDH |
13.7214 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PPARG, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3 |
13.4887 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC |
12.2739 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD17B1, NR3C1, NR3C2, PGR, RORC, SHBG |
10.5773 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
10.2001 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, PPARG, RORC |
10.1888 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, PPARG, RORC |
10.1888 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
10.0558 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.8757 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.75595 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, TEK, TRPV1 |
9.67329 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AR, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PPARG, PRKCE, RORC, SMAD3, TEK, TRPV1 |
8.73943 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
8.6579 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, F10, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, HSP90AA1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SRC, TEK, TOP2A, TYR, XDH |
8.60132 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AR, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, TEK, TRPV1 |
8.51724 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AR, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, TEK, TRPV1 |
8.18354 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, GPER1, HSD17B1, IGF1R, INSR, NQO2, NR3C1, SHBG |
8.09763 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.65243 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.31149 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
7.19441 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, GPER1, HSD17B1, NR3C1, NR3C2, PGR, PPARA, PPARG, RORC, SHBG, TRPV1 |
7.09421 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.83119 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.62522 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD11B1, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.62522 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.50979 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.28259 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.24376 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.18614 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.88675 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, XDH |
5.74861 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.67277 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC |
5.47573 |
|
[MF] GO:0030235 |
nitric-oxide synthase regulator activity
|
EGFR, ESR1, HSP90AA1, HSP90AB1 |
5.47573 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRB, GRM5, HSP90AA1, HSP90AB1, HSPA1A, MET, NR3C1, PGR, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A |
5.2541 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
5.24399 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, SRC |
5.2252 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.1456 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, AOX1, APP, AURKB, AXL, CSNK2A1, EGFR, F10, FABP3, FABP4, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
5.12056 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.89408 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TYR |
4.84305 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.83842 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.66731 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, EGFR, ESR1, ESR2, FLT3, GRIK5, HSP90AA1, HSP90AB1, IGF1R, KDR, MET, MMP9, NQO2, PGR, PPARG, PTGS2, SLC22A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
4.63427 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.61904 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, EGFR, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARG, TEK, TRPV1 |
4.33735 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, EGFR, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARG, TEK, TRPV1 |
4.33735 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.28482 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
4.21564 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.16362 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.16267 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.95575 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B1, NQO2, PTGS1, PTGS2, SRC, XDH |
3.91804 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
3.90022 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, HSP90AA1, HSP90AB1, NR3C1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
3.85274 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, HSP90AA1, HSP90AB1, NR3C1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
3.82312 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.70215 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.58928 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.58347 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HSP90AA1, HSP90AB1, IGF1R, INSR, KDR, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.57052 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.42376 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PPARG, PRKCB, SMAD3, SRC |
3.35008 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD17B1, HSD17B2, XDH |
3.31659 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD17B1, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PPARG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
3.31232 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.26514 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.22125 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.21392 |
|
[MF] GO:0015238 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.20627 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.16193 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.16193 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.16193 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HSP90AB1, HSPA1A, KDR, NR3C1 |
2.96598 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ADORA1, APP, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSP90AA1, HSP90AB1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.95523 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.90907 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.90499 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, MET, PPARA, PPARG, PTPN1, SMAD3 |
2.85646 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CSNK2A1, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
2.84521 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.84521 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.84521 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.84521 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.84521 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
2.81099 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.80985 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, AR, BCL2, ESR1, ESRRB, FLT3, PIM1, PPARA, PPARG, PRKCB, SMAD3, SRC |
2.51901 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.43904 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.43904 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.43904 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.43904 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.43904 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.43904 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.43904 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.43904 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.43121 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.40011 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CSNK2A1, DUSP3, EGFR, F10, FLT3, HSP90AA1, IGF1R, INSR, KDR, MET, MMP1, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
2.3951 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, AOX1, AR, AXL, BCL2, EGFR, FLT3, HSP90AA1, HSP90AB1, NQO2, PPARG, PTGS2, SLC22A1, SMAD3, TOP2A, TYR, XDH |
2.38223 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.30807 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.27799 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.27799 |
|
[MF] GO:0035257 |
None
|
ESR1, FLT3, PPARG, PRKCB, SMAD3, SRC |
2.26764 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.19475 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.19475 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.19475 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.19475 |
|
[MF] GO:0000978 |
None
|
AR, ESR1, ESR2, ESRRA, NR3C1, PGR, PPARA, RORC, SMAD3 |
2.05868 |
|
[MF] GO:0015101 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.02098 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.01502 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ACHE, AOX1, BCL2, FLT3, HSP90AA1, HSP90AB1, NQO2, PTGS2, SLC22A1, SMAD3, TOP2A, TYR, XDH |
2.00518 |
|
[MF] GO:0030594 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM5 |
2.00444 |
