| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MMP2, MMP9, MPO, PPARA, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
13.7443 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MPO, PPARA, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
12.3877 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, INSR, KDR, MET, PPARA, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, XDH |
11.3313 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MMP9, MPO, PPARA, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
10.3055 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.99214 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PPARA, PTGS2, TRPV1 |
9.96971 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.90528 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PTAFR, PTGS2, SMAD3, SRC, TEK, XDH |
9.88751 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.88222 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, IDO1, MPO, PTAFR, PTGS2, RORC, SRC, TYR |
9.78702 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.3988 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.29015 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.20289 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.17315 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.00911 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
8.94225 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1 |
8.92681 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
8.88784 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.88784 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, PTAFR, PTGS2, SRC, TEK, TRPV1 |
8.87098 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESRRB, F3, FABP4, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HSD17B2, HTR1A, IDO1, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, MPO, PIM1, PPARA, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
8.74763 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.29153 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.63555 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.63555 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.59552 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, IDO1, MPO, PIM1, PPARA, PTAFR, PTGS2, TYR, XDH |
7.47501 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PTAFR, PTGS2, TEK |
7.46634 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.32701 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, ESRRA, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IDO1, INSR, KDR, MET, MMP12, MMP2, MMP9, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.00945 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.95015 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.88437 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
6.82822 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD2, EGFR, F3, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
6.77082 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, PTGS2, PTPN1, SRC, TEK, XDH |
6.7518 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CHRM2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, MPO, NUAK1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR |
6.70386 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD2, EGFR, HCAR2, HMGCR, KDR, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
6.70386 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MPO, PTGS2, TYR, XDH |
6.66203 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, DRD2, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, MMP2, MPO, PPARA, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
6.57018 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.5257 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, IGF1R, INSR, KDR, MMP2, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
6.5257 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.5257 |
|
[BP] GO:0007215 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
6.38134 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.38134 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
6.38134 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, BACE1, CA2, CA7, DRD2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.38134 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, BACE1, CA2, CA7, DRD2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.38134 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A |
6.35972 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.22238 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.19173 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM2, DRD2, GRM1, GRM3, GRM5, GRM8, HTR1A |
6.17425 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.12616 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PTGS2, SRC |
6.06456 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.04592 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.02683 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.9922 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MMP2, MMP9, MPO, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
5.95655 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD2, EGFR, FABP3, HMGCR, HSD11B2, KDR, PTAFR, PTGS2, SRC, TRPV1 |
5.81399 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
5.77632 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP2, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.77336 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
5.76816 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.75072 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CHRM2, CSNK2A1, CYP1B1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
5.69595 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PTAFR, PTGS2, RORC, SRC, TRPV1 |
5.69215 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, DRD2, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
5.63496 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PPARA, PTGS2 |
5.54608 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.50644 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.49974 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.49642 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CHRM2, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MMP12, MMP9, PIM1, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
5.48994 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
5.48694 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
5.38096 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.37403 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.35091 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.35091 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.30702 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD2, EGFR, GRIK5, HTR1A, INSR, PTGS2, SLC1A1, SMAD3, TRPV1 |
5.28178 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IDO1, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.22509 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
5.22061 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, DRD2, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
5.20085 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.18593 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, AXL, BCL2, CA12, CA2, CA7, DRD2, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, INSR, MET, SMAD3, SRC, TRPV1 |
5.1561 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.1561 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
5.11292 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.09258 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.02064 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
5.01316 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTAFR, PTGS2 |
4.97332 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.97112 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
4.9173 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KDR, PTAFR, PTGS2, SRC, TRPV1 |
4.90774 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CYP1B1, DRD2, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
4.90127 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTAFR, PTGS2, RORC, SRC, TRPV1 |
4.90073 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.85786 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.85592 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, GRM5, PTAFR |
4.83524 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.7967 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TRPV1, XDH |
4.73491 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPI, ALPL, AOX1, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
4.73491 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
4.73297 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CA7, CYP19A1, DRD2, EGFR, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, INSR, MMP12, MMP9, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
4.59553 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM2, DRD2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR6 |
4.58155 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
4.57103 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
4.57067 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.53377 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.47775 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
4.45009 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, DRD2, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, INSR, MET, SMAD3, TRPV1 |
4.42127 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, DRD2, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
4.39992 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
4.33794 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, SRC, TNKS, TNKS2, TRPV1 |
4.32132 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTAFR, PTGS2, SMAD3, SRC, TEK |
4.29507 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.28674 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
4.28657 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.27885 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.24846 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD2, GBA2, HMGCR, HTR1A, PTAFR, TYR |
4.22783 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, FABP3, PPARA, SLC1A1, TRPV1 |
4.18625 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, GBA2, HSPA1A, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, SRC, XDH |
4.17263 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, MPO, PTGS2, SRC |
4.16911 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
4.16807 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
4.16401 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.16103 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, F3, FABP4, HMGCR, IDO1, KDR, MET, MMP12, PPARA, PTGS2, SMAD3, TEK |
4.16095 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, EGFR, F3, INSR, MET, SRC, TEK, XDH |
4.13689 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.13689 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2, SRC |
4.12581 |
|
[BP] GO:0003018 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2, SRC, TEK |
4.12581 |
|
[BP] GO:0007188 |
None
|
ADORA1, CHRM2, DRD2, GRM1, GRM3, GRM5, GRM8, HTR1A |
4.10712 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.08083 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.0807 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
4.0807 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TRPV1, TYR |
4.07659 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
4.07276 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.06481 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM2, DRD2, EGFR, GPR35, GRM1, HCAR2, PTAFR, PTGS2, SLC1A1, SMAD3, TRPV1 |
4.05883 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, EGFR, ESR1, PPARA, RORC, SRC, TOP2A |
4.04754 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, BCL2, CDK6, CYP19A1, DRD2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.04434 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2, SRC |
4.03831 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, IDO1 |
4.03784 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.0357 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.03094 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, MMP9, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.02461 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DRD2, EGFR, HSPA1A, IDO1, MPO |
3.99424 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HCAR2, HMGCR, PPARA, PTGS2, RORC, SRC, TEK |
3.99191 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
3.97538 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.96556 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD2, EGFR, HCAR2, PTGS2, TNKS, TNKS2 |
3.94551 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.9188 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PTGS2, SMAD3, TRPV1, XDH |
3.89648 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
3.89336 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.87056 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.87056 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.87056 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, MMP9, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.86873 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.85596 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.84573 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.82095 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
3.80439 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.80401 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, AURKB, BCL2, CSNK2A1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
3.79573 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, EGFR, PPARA, SMAD3 |
3.73924 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
3.71431 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.70819 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.70311 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, IDO1, PPARA, PTGS2 |
3.69134 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, EGFR, GRM5, IGF1R, INSR, MMP2, PTAFR, PTGS2, SRC, TRPV1 |
3.69134 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, CHRM2, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, PTGS2, SLC1A1, TEK, TRPV1 |
3.68182 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTAFR, PTGS2 |
3.67467 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.63164 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD2, HMGCR, KDR, SRC |
3.62779 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.61489 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TRPV1, TYR |
3.60263 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, EGFR, ESR1, FLT3, GRM5, IGF1R, INSR, MMP2, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
3.56191 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PTAFR, PTGS2, SRC, TOP2A |
3.55695 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, MET, MMP9, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.55328 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
3.53373 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.51671 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.50791 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.50791 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
3.49132 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2 |
3.46712 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.46342 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1, XDH |
3.46322 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, PTPN1, SRC |
3.46173 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, DRD2, EGFR, FLT3, GRM1, HMGCR, INSR, KDR, PTPN1, SRC, TEK, XDH |
3.44685 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.42806 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PTAFR, SRC |
3.42806 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.42032 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
3.42032 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, EGFR, GRM5, IGF1R, INSR, MMP2, PTAFR, PTGS2, SRC, TRPV1 |
3.40869 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CHRM2, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, IDO1, MMP12, MPO, PTAFR, PTGS2, SMAD3, SRC, TRPV1, TYR |
3.38103 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, HSD11B2, HSPA1A, HTR1A, IDO1, MMP2, MMP9, MPO, NUAK1, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
3.37475 |
|
[BP] GO:0003013 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2, SRC, TEK |
3.37098 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.35523 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, DRD2, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
3.3548 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.34994 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
3.33508 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DUSP3, EGFR, HSPA1A, INSR, PIM1, PTGS2, SMAD3, SRC, TNKS, TOP2A |
3.33508 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD2, KDR, SRC, TRPV1 |
3.33508 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
3.32652 |
|
[BP] GO:0008217 |
None
|
ADORA1, DRD2, HSD11B2, PPARA, PTAFR, PTGS2, SMAD3 |
3.30358 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.30349 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.26907 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.2589 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, SRC, TEK |
3.25344 |
|
[BP] GO:0007610 |
None
|
BCL2, DRD2, EGFR, GRM1, GRM5, HMGCR, HTR1A, IDO1, INSR, PPARA, PTGS2, TRPV1 |
3.24029 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
3.24022 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK |
3.21212 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, FABP3, PPARA, SLC1A1, TRPV1 |
3.20942 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
3.20942 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, MPO |
3.19999 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CYP19A1, DRD2, EGFR, HCAR2, INSR, MMP12, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
3.19942 |
|
[BP] GO:0007268 |
None
|
CHRM2, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1 |
3.1837 |
|
[BP] GO:0098916 |
None
|
CHRM2, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1 |
3.1837 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
3.1837 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.16629 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.16085 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALPI, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PTGS2 |
3.16085 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PTGS2 |
3.14369 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, PIM1, SRC, TEK, TYR |
3.138 |
|
[BP] GO:0099536 |
None
|
CHRM2, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1 |
3.11534 |
|
[BP] GO:0099537 |
None
|
CHRM2, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1 |
3.11534 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, MMP12, PTAFR, SRC, TRPV1 |
3.09255 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MPO |
3.08571 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
3.08571 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.0691 |
|
[BP] GO:0050801 |
ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD2, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, SMAD3, TRPV1 |
3.04891 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PTGS2, SMAD3, TEK |
3.04462 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.03732 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
3.02072 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
3.01155 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
2.98859 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.9814 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA, SMAD3, TEK |
2.97948 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.97076 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PTPN1, SRC |
2.9662 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, PTPN1, SRC, TEK, TNKS |
2.95834 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, BCL2, CYP1B1, DRD2, EGFR, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HTR1A, INSR, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
2.9576 |
|
[BP] GO:0042391 |
None
|
ADORA1, BCL2, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
2.95089 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, PTAFR, SRC |
2.95089 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.94853 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, AURKB, BCL2, CSNK2A1, DRD2, DUSP3, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.94853 |
|
[BP] GO:0010038 |
response to metal ion
|
BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGS2 |
2.93013 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.92557 |
|
[BP] GO:0051172 |
None
|
APEX1, AURKB, CSNK2A1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.90648 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTAFR, PTGS2, SRC |
2.90442 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
2.89233 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.89111 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTAFR, PTGS2, SMAD3, SRC |
2.8743 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PTGS2, SRC |
2.86905 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD2, EGFR, HTR6 |
2.86164 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, DRD2, EGFR, PTGS2 |
2.85321 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PTAFR, RORC, SRC |
2.85321 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.84513 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
2.82097 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
AURKB, AXL, BCL2, DRD2, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.82077 |
|
[BP] GO:0097746 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2 |
2.80507 |
|
[BP] GO:0035296 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2 |
2.80507 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR, HMGCR |
2.78798 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.78798 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.777 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.76776 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.76168 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, IDO1, MPO, PIM1, PPARA, PTGS2, TYR |
2.74698 |
|
[BP] GO:0007267 |
None
|
ADORA1, CHRM2, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, TEK |
2.70707 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD2, HTR1A, TYR |
2.70559 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTAFR, PTGS2, SMAD3, SRC |
2.70222 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.70222 |
|
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, HTR1A, PTGS2 |
2.70117 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.70117 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, MMP12, PTAFR, SRC, TRPV1 |
2.70117 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.69332 |
|
[BP] GO:0050793 |
regulation of developmental process
|
AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, IDO1, INSR, KDR, NUAK1, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
2.67701 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
2.67639 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.67639 |
|
[BP] GO:0050880 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2 |
2.67639 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, IDO1, MPO, PIM1, PPARA, PTGS2, TYR |
2.67613 |
|
[BP] GO:0035150 |
None
|
ADORA1, EGFR, HMGCR, HTR1A, PTAFR, PTGS2 |
2.66047 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.65832 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, IDO1, PIM1, PPARA, PTGS2, TYR |
2.63381 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, KDR, MET, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.6329 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, SMAD3, TRPV1 |
2.62954 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ADORA1, CA2, CA7, GRM5, PTAFR |
2.62954 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.62954 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.62954 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
DRD2, DUSP3, EGFR, HMGCR, KDR, PTPN1, SRC, TEK |
2.62542 |
|
[BP] GO:0045776 |
None
|
ADORA1, DRD2, PPARA, PTAFR |
2.60072 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
2.5956 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, PTPN1, SRC, TEK |
2.58668 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, IDO1, KDR, MET, PTGS2, SMAD3 |
2.57593 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.56467 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.55475 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
2.54914 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.54914 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, GPR35, MMP9, PTGS2 |
2.54502 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.52404 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, CHRM2, DRD2, EGFR, PTAFR, PTGS2, SLC1A1 |
2.52149 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DRD2, DUSP3, EGFR, INSR, SRC |
2.50721 |
|
[BP] GO:0051704 |
multi-organism process
|
AXL, BCL2, CDK6, CHRM2, CYP1A1, EGFR, HSD11B2, HSPA1A, IDO1, INSR, KDR, MET, MMP1, MMP12, MPO, PTAFR, SMAD3, SRC |
2.50721 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.4989 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTAFR, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.49239 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, IDO1, KDR, NUAK1, PPARA, PTAFR, SMAD3, SRC, TEK |
2.48245 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, IDO1, MMP12, MMP2, PTAFR, PTPN1, SMAD3, SRC |
2.47819 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.47819 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.47339 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.45278 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.44736 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.44736 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.44736 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.44735 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
2.42338 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, MMP12, PTAFR, SRC |
2.41515 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.38763 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, CA2, CHRM2, DRD2, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, INSR, PTAFR, SRC |
2.38763 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PPARA, PTPN1, SMAD3 |
2.38763 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.38639 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DRD2, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1 |
2.35322 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.34869 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.34869 |
|
[BP] GO:0023052 |
None
|
ADORA1, CHRM2, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR6, SLC1A1, TEK |
2.3328 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HSPA1A, IDO1, MMP12, PTAFR, PTGS2, SMAD3, SRC |
2.32975 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.32745 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, PPARA, RORC, TOP2A |
2.31479 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.31378 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.31378 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, IDO1, PTGS2, SMAD3, XDH |
2.3132 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CYP1A1, HMGCR, MPO, PTGS2 |
2.29146 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.28734 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.26793 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.26606 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.26606 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.26606 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.26606 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.26606 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
2.26606 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, PTPN1, SRC |
2.25897 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.24511 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, BCL2, CA2, CA7, DRD2, GPR35, GRM5, HTR1A, MMP9, PTAFR, PTGS2 |
2.24423 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.23936 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.23936 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, EGFR, HSPA1A, INSR, TNKS |
2.23793 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.21698 |
|
[BP] GO:0032094 |
None
|
CYP1A1, HSD11B2, MPO |
2.21698 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, MMP9, MPO, PTAFR, RORC, SMAD3, SRC, TRPV1 |
2.20432 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.19993 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.19993 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.19993 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, PTPN1, SRC |
2.19738 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.19275 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.18559 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
BCL2, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, SMAD3, TRPV1 |
2.18321 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.16935 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.16884 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.16648 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.15633 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.14979 |
|
[BP] GO:0055080 |
cation homeostasis
|
BCL2, CA2, CA7, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, SMAD3, TRPV1 |
2.14529 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, INSR, PPARA, PTAFR, RORC, SRC |
2.12436 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.11646 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.11387 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.08737 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, PTAFR, SRC |
2.0755 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MMP12, SRC |
2.07125 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.06763 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.0652 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, RORC |
2.05764 |
|
[BP] GO:0051098 |
regulation of binding
|
AURKB, BCL2, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
2.05621 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX5, CYP19A1, CYP1A1, HMGCR, IDO1, MPO, PTAFR, PTGS2 |
2.0443 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, SMAD3, TEK |
2.04275 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PTGS2, PTPN1, XDH |
2.03671 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD2, HTR1A |
2.03363 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK |
2.0321 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.02396 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, RORC |
2.02395 |
|
[BP] GO:0040008 |
regulation of growth
|
BCL2, CSNK2A1, DRD2, EGFR, ESR2, HSPA1A, INSR, MPO, PIM1, SMAD3, TNKS2 |
2.02395 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
BCL2, CA2, CA7, DRD2, ESR1, GPR35, GRIK5, GRM1, GRM5, SMAD3, TRPV1 |
2.02395 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.02242 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.02242 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.02242 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.02242 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PPARA, SMAD3 |
2.01424 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A |
2.01424 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD2, MET, TRPV1 |
2.01268 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD2, PTGS2 |
2.01202 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.01202 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.01154 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, PTPN1, SRC |
2.01047 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.00312 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.00005 |
|
[BP] GO:0035235 |
None
|
GRIA2, GRIA4, GRIK5 |
2.00005 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.00005 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.00005 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, GBA2, HSPA1A, IDO1, XDH |
2.00005 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.00005 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM2, PTAFR, PTGS2 |
2.00005 |
|
[BP] GO:0051926 |
negative regulation of calcium ion transport
|
BCL2, DRD2, GPR35, PTGS2 |
2.00005 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, CA2, CA4, CA9, CHRM2, DRD2, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, PTGS2, SLC1A1, SRC, TEK, TRPV1 |
6.10637 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, AXL, BACE1, CA4, CHRM2, DRD2, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, TEK, TRPV1 |
5.77632 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALPI, ALPL, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CHRM2, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, MMP2, PIM1, PTAFR, PTPN1, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
5.54608 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, ALPI, ALPL, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, MMP2, PIM1, PTAFR, PTGS2, PTPN1, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, TYR |
5.28389 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, AXL, BACE1, CA2, CA4, CA9, CHRM2, DRD2, DUSP3, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, PTGS2, SLC1A1, SRC, TEK, TRPV1 |
5.15538 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, AXL, BACE1, CHRM2, DRD2, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, TEK, TRPV1 |
4.94086 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ALPI, ALPL, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, PTGS2, PTPN1, SLC1A1, SRC, TEK, TRPV1, TYR |
4.45344 |
|
[CC] GO:0097060 |
None
|
CHRM2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, TRPV1 |
3.23017 |
|
[CC] GO:0042734 |
None
|
GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.11534 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, SRC, TRPV1 |
2.90511 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2 |
2.88194 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2, PTPN1 |
2.84513 |
|
[CC] GO:0014069 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, SRC |
2.64458 |
|
[CC] GO:0099572 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, SRC |
2.64458 |
|
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.60072 |
|
[CC] GO:0043005 |
None
|
ADORA1, BACE1, CA2, CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PTGS2, SRC |
2.41196 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA7, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, INSR, KDR, MMP2, MMP9, MPO, PIM1, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.38969 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, BACE1, CA2, CDK6, CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR6, PTGS2, SRC, TEK |
2.31792 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, BCL2, CA4, CYP19A1, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, KDR, PTGS2, PTPN1, XDH |
2.27316 |
|
[CC] GO:0043235 |
receptor complex
|
EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.21355 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, BACE1, CA2, CDK6, CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR6, PTGS2, SRC, TEK |
2.07153 |
|
[CC] GO:0097458 |
None
|
ADORA1, BACE1, CA2, CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IDO1, INSR, PTGS2, SRC, TRPV1 |
2.02627 |
|
[CC] GO:0043197 |
None
|
ADORA1, DRD2, GRIA2, GRIA4, GRM3 |
2.01268 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.00728 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, ALPI, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
13.4896 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
11.1829 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM2, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
10.8328 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, CHRM2, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
9.99214 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
9.99214 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CHRM2, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
9.78702 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.55716 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CHRM2, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PPARA, PTAFR, RORC, SMAD3, TEK, TRPV1 |
9.46647 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MPO, PTGS2, TYR, XDH |
8.0877 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.71138 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM2, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, TEK, TRPV1 |
7.60815 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM2, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, IGF1R, INSR, KDR, MET, PTAFR, TEK, TRPV1 |
7.60815 |
|
[MF] GO:0008270 |
zinc ion binding
|
ALPI, CA1, CA12, CA2, CA4, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PPARA, PTPN1, RORC, SMAD3, TNKS |
7.32867 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, ESR1, ESR2, ESRRA, ESRRB, GLO1, HTR1A, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.12438 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MPO, PTGS2, SRC |
6.77082 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.7518 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MPO, PTGS2, SRC |
6.5257 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.23842 |
|
[MF] GO:0030594 |
None
|
CHRM2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR6 |
6.22364 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.20834 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.06224 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.90914 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HMGCR, HSD11B2, HSD17B1, IDO1, MPO, PTGS2, SRC, XDH |
5.84371 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.80638 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.52153 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, DRD2, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, SRC, TEK, TOP2A, TRPV1 |
5.14945 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, XDH |
5.01074 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.97332 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.7967 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.7967 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.65328 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.61593 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
4.57067 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
4.39433 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.36283 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2, TYR |
4.12581 |
|
[MF] GO:0019899 |
enzyme binding
|
ALPI, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, MET, PPARA, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.92968 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.85596 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.75655 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.6944 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.62915 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, PTAFR, RORC, TRPV1 |
3.60987 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.51058 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.24022 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.19401 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.138 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
3.08571 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.08098 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, MET, MMP9, PTGS2, SMAD3, TOP2A, TRPV1, TYR, XDH |
3.03895 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.98959 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
2.90442 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.84513 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.84513 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.84513 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
2.70007 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.64358 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR |
2.56397 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.53194 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.44736 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.40467 |
|
[MF] GO:0043168 |
anion binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MPO, NUAK1, PIM1, PTAFR, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
2.34191 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.32745 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.32745 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.19993 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.19993 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.18407 |
|
[MF] GO:0008227 |
None
|
CHRM2, DRD2, HTR1A, HTR6 |
2.16648 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, BACE1, GRIA2, INSR |
2.08737 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, CHRM2, DRD2, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR6, PTAFR |
2.07277 |
|
[MF] GO:0035586 |
None
|
ADORA1, ADORA3, PTAFR |
2.02396 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, TRPV1, XDH |
2.02395 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.02395 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, TRPV1, XDH |
2.02395 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.02242 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.02242 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.01539 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PTPN1 |
2.01268 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.00605 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.00005 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
2.00005 |
|
[MF] GO:0099094 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.00005 |
