| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MMP2, MMP9, MPO, PPARA, PTGS2, RORC, SRC, TEK, TYR |
12.5964 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, IDO1, MPO, PTGS2, RORC, SRC, TYR |
11.8801 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MPO, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
11.8801 |
|
[BP] GO:0042221 |
response to chemical
|
ABCG2, AKR1B1, ALPL, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MMP9, MPO, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
10.7342 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1B1, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGS2, SMAD3, SRC, TEK, XDH |
10.2012 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCG2, ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MET, PPARA, PTGS2, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.75061 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.44242 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.43217 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.29908 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.74834 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.7432 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PPARA, PTGS2, TBXAS1 |
8.49868 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
8.18324 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.0874 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRB, F3, FABP4, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, MPO, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TYR |
8.06429 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.05056 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.92321 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.92321 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.89911 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.77789 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FUT7, GBA2, HMGCR, HSPA1A, IDO1, MPO, PIM1, PPARA, PTGS2, TBXAS1, TYR, XDH |
7.70861 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.64734 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTGS2, RORC, SRC, TEK, TYR |
7.55032 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR6, IDO1, INSR, KDR, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.54386 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MMP2, MMP9, MPO, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TYR |
7.5416 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.46511 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
7.38106 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.33201 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
7.14262 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, EGFR, ESR1, F3, FLT3, HMGCR, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK |
7.10398 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IDO1, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.07251 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.80137 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.71101 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, CNR1, EGFR, HCAR2, HMGCR, KDR, PTGS2, SRC, TNKS, TNKS2 |
6.67288 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
6.61331 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALPL, AURKB, AXL, BCL2, CA2, CA9, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, MPO, NUAK1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TYR |
6.61331 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
6.57648 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CYP1B1, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR6, INSR, KDR, MET, PTGS2, PTPN1, SRC, TEK, XDH |
6.47494 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
6.33634 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, TYR |
6.33634 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, BCL2, CDK6, CHRM1, CHRM4, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
6.33634 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MPO, PTGS2, TBXAS1, TYR, XDH |
6.30425 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GBA2, HMGCR, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP2, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
6.13946 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
6.09712 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.98404 |
|
[BP] GO:0042493 |
response to drug
|
ABCG2, AKR1B1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, EGFR, FABP3, HMGCR, HSD11B2, KDR, PTGS2, SRC |
5.96635 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GPR35, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.84264 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, AXL, BCL2, CA2, CA7, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1B1, EGFR, F3, GPR35, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
5.79816 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.79068 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.76369 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, BCL2, CDK6, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.66683 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F3, FABP4, HMGCR, IDO1, KDR, MET, MMP12, PPARA, PTGS2, SMAD3, TEK |
5.62455 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, HSPA1A, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
5.59879 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CNR1, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, HCAR2, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SMAD3, SRC, TEK, TNKS2, XDH |
5.59879 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
5.50738 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GPR35, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
5.33569 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.33569 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, FABP3, FLT3, HCAR2, HMGCR, PPARA, PTGS2, RORC, SRC, TEK |
5.31123 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GPR35, HCAR2, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, MPO, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.23829 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
5.23829 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, MMP9, PTGS2, SRC |
5.12614 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TYR, XDH |
5.07928 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC |
5.03082 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PTGS2, SMAD3, TEK |
5.03082 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, BCL2, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.96547 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.93068 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, EGFR, HMGCR, HSD11B2, HSPA1A, MMP2, MPO, PPARA, PTGS2, SMAD3, SRC, TEK, TYR |
4.92957 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.90131 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.90131 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.88994 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
4.8638 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.80354 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.80205 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, CNR2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
4.76794 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.765 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, CNR2, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
4.75464 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.70202 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
4.65291 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.64598 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TYR |
4.62051 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
4.57828 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.54341 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
4.5397 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.53755 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2 |
4.52292 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PPARA, PTGS2, TBXAS1 |
4.51122 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, MMP2, PTGS2, RORC, SMAD3, SRC |
4.48465 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.40723 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.39079 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.38404 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EGFR, ESR1, FLT3, MET, PIM1, SRC, TEK, TYR |
4.38085 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, CNR1, CNR2, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
4.38085 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.37658 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.3733 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
4.37188 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, EGFR, HCAR2, PTGS2, TNKS, TNKS2 |
4.35253 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.3038 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CNR1, CYP1B1, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SMAD3, SRC, TEK |
4.29493 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, IDO1, MMP12, MPO, PTGS2, SMAD3, SRC, TYR |
4.27496 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, GBA2, HSPA1A, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, SRC, XDH |
4.26466 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.15325 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
4.14868 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, HMGCR, KDR, SRC |
4.11597 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTGS2, SMAD3, SRC |
4.09403 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TYR |
4.0905 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
4.07321 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
4.07321 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.0722 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.0722 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
4.04937 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.03467 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, CNR1, CNR2, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
4.03467 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.02805 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.02052 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.93823 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.93455 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, AURKB, BCL2, CNR1, CNR2, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
3.91585 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PTGS2, SMAD3, SRC |
3.90827 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
3.90703 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PTGS2, SRC |
3.8908 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, MPO, PTGS2, SRC |
3.88132 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, AKR1B1, AXL, BCL2, CA12, CA2, CA7, CNR1, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, INSR, MET, SMAD3, SRC |
3.87724 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.8428 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.8428 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.81165 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.79594 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PTGS2, PTPN1, RORC, SMAD3, SRC |
3.77668 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, IDO1, KDR, MET, PTGS2, SMAD3 |
3.70125 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, EGFR, GPR35, HCAR2, HMGCR, HSPA1A, INSR, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC |
3.64621 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, SRC, TEK, XDH |
3.62614 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
3.59852 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.58556 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
3.57245 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.5497 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
3.5497 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.54878 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, SRC, TEK |
3.54878 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.54878 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.53892 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
AURKB, AXL, BCL2, CNR1, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.53275 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.50714 |
|
[BP] GO:0003018 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2, SRC, TEK |
3.50714 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.45659 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, MPO |
3.44303 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
3.42304 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.40092 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, AKR1B1, BCL2, CA12, CA2, CA7, CNR1, EGFR, ESR1, FABP3, FABP4, GPR35, INSR, MET, SMAD3 |
3.39133 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PTGS2, SRC |
3.37581 |
|
[BP] GO:0050793 |
regulation of developmental process
|
AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, IDO1, INSR, KDR, NUAK1, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, XDH |
3.35947 |
|
[BP] GO:0065007 |
biological regulation
|
ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
3.35758 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
3.33052 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
3.33052 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.33052 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.33052 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PTGS2, SMAD3, XDH |
3.29966 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
3.29583 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.28361 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, MMP12, PPARA, SMAD3, TEK |
3.2768 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, IDO1, MMP12, MMP2, PTPN1, SMAD3, SRC |
3.25238 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.23343 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MPO |
3.23107 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CHRM4, CSNK2A1, EGFR, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.22811 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.22219 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, SMAD3, TEK |
3.20233 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, EGFR, ESRRB, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.20115 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, EGFR, HSPA1A, IDO1, MPO |
3.17131 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, EGFR, PPARA, SMAD3 |
3.16914 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.1565 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AXL, CDK6, CYP1B1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, PTGS2, RORC, SRC |
3.14898 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC |
3.13295 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, HMGCR, IDO1 |
3.12055 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, HTR6 |
3.11825 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
3.08914 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
3.0581 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, MET, PPARA, SMAD3 |
3.05805 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, FABP3, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK |
3.05562 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTGS2, RORC, SRC |
3.03768 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS |
3.03547 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR, HMGCR |
3.02942 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
3.02942 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, HCAR2, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
3.02798 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PTGS2 |
3.01744 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TYR |
2.99221 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.99221 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
2.98149 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.98149 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PPARA, PTPN1, SMAD3 |
2.9642 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.96017 |
|
[BP] GO:0009987 |
cellular process
|
ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
2.95769 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.95307 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.94889 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.87911 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CDK6, CYP1B1, EGFR, KDR, PTGS2, SRC |
2.87911 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.87592 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, PPARA, RORC, SRC |
2.86742 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, CA2, CHRM1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.86742 |
|
[BP] GO:0003013 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2, SRC, TEK |
2.85824 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.85541 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.84801 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, EGFR, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
2.83249 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, GBA2, IDO1, PPARA, PTGS2, TBXAS1 |
2.82654 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.82654 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.82545 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2 |
2.8214 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, GPR35, MMP9, PTGS2 |
2.78785 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.77955 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.77955 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
2.77195 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.77195 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.77195 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CHRM1, CYP19A1, EGFR, HCAR2, INSR, MMP12, PTGS2, SMAD3, SRC |
2.76753 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.76753 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA, PTGS2, TBXAS1 |
2.76753 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, GBA2, IDO1, MPO, PIM1, PPARA, PTGS2, TBXAS1, TYR |
2.76141 |
|
[BP] GO:0051704 |
multi-organism process
|
AXL, BCL2, CDK6, CHRM2, CYP1A1, EGFR, HSD11B2, HSPA1A, IDO1, INSR, KDR, MET, MMP1, MMP12, MPO, SMAD3, SRC |
2.75834 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, HMGCR, SRC, TNKS, TNKS2 |
2.75557 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.74734 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA2, CA7, CNR1, CNR2, EGFR, PTGS2 |
2.72568 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA2, CA7, CNR1, CNR2, EGFR, PTGS2 |
2.72568 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.71879 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.69619 |
|
[BP] GO:0008217 |
None
|
ADORA1, CNR1, HSD11B2, PPARA, PTGS2, SMAD3 |
2.6828 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
AXL, BCL2, CA2, CNR1, CYP1B1, ESRRB, F3, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK |
2.67891 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, XDH |
2.666 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.65039 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, AXL, CDK6, CNR1, CNR2, CYP19A1, DUSP3, IDO1, MMP12 |
2.63836 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, EGFR, FLT3, HMGCR, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.63305 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.62334 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.62334 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, EGFR, ESR1, ESRRA, F3, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK, XDH |
2.60606 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
2.60301 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, F3, FLT3, HSPA1A, INSR, MET, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.59548 |
|
[BP] GO:0007568 |
aging
|
AURKB, BCL2, CNR1, CYP1A1, HMGCR, MPO, PTGS2 |
2.58918 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, GBA2, HMGCR, TYR |
2.58576 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS |
2.5817 |
|
[BP] GO:0010038 |
response to metal ion
|
BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.57795 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.5666 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
2.56349 |
|
[BP] GO:0031349 |
positive regulation of defense response
|
CNR1, EGFR, FABP4, HSPA1A, IDO1, MMP12, MMP2, PTGS2, SRC |
2.56349 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
2.56349 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.5608 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.5608 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
2.55927 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, EGFR, HSD11B2, HSPA1A, IDO1, MMP2, MMP9, MPO, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
2.55606 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.54891 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.54891 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
2.53241 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
2.52479 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PTGS2, SMAD3, SRC, TNKS |
2.52479 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PTGS2, PTPN1, XDH |
2.5049 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.5049 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.5049 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.5049 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.5049 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
2.5005 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.5005 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.48774 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.48774 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.48774 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.48774 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.46396 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.46396 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA |
2.46396 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.44651 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.43562 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.43512 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, IDO1, KDR, NUAK1, PPARA, SMAD3, SRC, TEK |
2.4123 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.41204 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, AXL, BCL2, CDC25B, CDK6, CYP1A1, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, HMGCR, KDR, MET, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC, TEK |
2.41204 |
|
[BP] GO:0051098 |
regulation of binding
|
AURKB, BCL2, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
2.41204 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.41204 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.41204 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.38651 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
AURKB, BCL2, CNR1, CSNK2A1, DUSP3, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.38651 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, BCL2, CYP1B1, SRC |
2.36946 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.36939 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.33321 |
|
[BP] GO:0032094 |
None
|
CYP1A1, HSD11B2, MPO |
2.33321 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.33321 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.33321 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.33321 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.32414 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, GBA2, IDO1, MPO, PIM1, PPARA, PTGS2, TBXAS1, TYR |
2.31354 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.28165 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2 |
2.28165 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.28165 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, EGFR, PTGS2 |
2.28165 |
|
[BP] GO:0070201 |
None
|
ACHE, BCL2, CHRM1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.2793 |
|
[BP] GO:0050729 |
positive regulation of inflammatory response
|
CNR1, EGFR, FABP4, IDO1, PTGS2 |
2.27769 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.26382 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.26382 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.26382 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.26382 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.26382 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, BCL2, CDK6, CYP1B1, FABP3, HSPA1A, IDO1, PTGS2, SMAD3, XDH |
2.26133 |
|
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.26103 |
|
[BP] GO:0050890 |
None
|
ADORA1, CHRM1, CNR1, EGFR, HMGCR, INSR, PTGS2 |
2.24621 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.24621 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR6, KDR, MMP1, MMP12, MMP9, SRC, TEK |
2.24621 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.24621 |
|
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM4 |
2.24621 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.24621 |
|
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM4 |
2.24621 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, FUT7, GBA2, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TYR, XDH |
2.23371 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
DUSP3, EGFR, HMGCR, KDR, PTPN1, SRC, TEK |
2.23289 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.22619 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.21497 |
|
[BP] GO:0043434 |
None
|
FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
2.20011 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, EGFR, ESR1, F3, FLT3, HSPA1A, INSR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.20011 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.19972 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, HMGCR, PPARA, SMAD3, TEK |
2.19319 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK |
2.19191 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, EGFR, PTGS2 |
2.19137 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.19137 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, PTGS2 |
2.18394 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.18394 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.16096 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM1, CHRM2, PTGS2 |
2.16096 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.15657 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, GBA2, IDO1, PIM1, PPARA, PTGS2, TBXAS1, TYR |
2.15422 |
|
[BP] GO:0097746 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2 |
2.1523 |
|
[BP] GO:0035296 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2 |
2.1523 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, PTGS2 |
2.1523 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.11434 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.11434 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.11434 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, SRC |
2.09726 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.09726 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.09515 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.09515 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.09515 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC |
2.08766 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.0865 |
|
[BP] GO:0043393 |
regulation of protein binding
|
AURKB, BCL2, MET, MMP9, PPARA, SRC |
2.0865 |
|
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.08025 |
|
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM4 |
2.08025 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, EGFR, FUT7, HTR6, KDR, MET, MMP1, MMP12, MMP9, SRC, TEK |
2.06048 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, KDR, SRC |
2.06048 |
|
[BP] GO:0050880 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2 |
2.05238 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, BCL2, CHRM1, CNR1, CSNK2A1, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.04709 |
|
[BP] GO:0046320 |
None
|
CNR1, FABP3, PPARA |
2.04315 |
|
[BP] GO:0009411 |
response to UV
|
AURKB, BCL2, EGFR, PTGS2, TYR |
2.04315 |
|
[BP] GO:0035150 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PTGS2 |
2.04315 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.03487 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, BCL2, CHRM1, EGFR, HCAR2, MMP12, PTGS2, SMAD3, SRC |
2.03101 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.03028 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.02007 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.01098 |
|
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.01098 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, EGFR, GPR35, HCAR2, PTGS2, SMAD3 |
2.01098 |
|
[BP] GO:0051172 |
None
|
AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.00889 |
|
[BP] GO:0033280 |
response to vitamin D
|
ALPL, PTGS2, TYR |
2.00889 |
|
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, EGFR, FLT3 |
2.00889 |
|
[BP] GO:0035239 |
tube morphogenesis
|
BCL2, EGFR, ESR1, MET, SMAD3, SRC |
2.0036 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.0036 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.0036 |
|
[CC] GO:0016020 |
membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ALOX5, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR6, IGF1R, INSR, KDR, MET, MMP2, PIM1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR |
3.45718 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCG2, ADORA1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, EGFR, INSR, MET, PTGS2, SRC, TEK |
3.24506 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, EGFR, ESR1, F3, FLT3, GBA2, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, MMP2, PIM1, PTPN1, SMAD3, SRC, TEK |
3.14421 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, AXL, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, F3, FLT3, GPR35, HTR6, IGF1R, INSR, KDR, MET, TEK |
2.96345 |
|
[CC] GO:0044425 |
membrane part
|
ABCG2, ACHE, ADORA1, ADORA3, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR6, IGF1R, INSR, KDR, MET, PTGS2, PTPN1, SRC, TBXAS1, TEK, TYR |
2.87592 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCG2, ADORA1, ADORA3, AXL, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DUSP3, EGFR, F3, FLT3, GPR35, HTR6, IGF1R, INSR, KDR, MET, PTGS2, SRC, TEK |
2.63812 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2, TBXAS1 |
2.43096 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.26208 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, GPR35, HTR6, IGF1R, INSR, KDR, MET, TEK |
2.24621 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, FLT3, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2, PTPN1, TBXAS1 |
2.13927 |
|
[CC] GO:0045121 |
membrane raft
|
CNR1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.09006 |
|
[CC] GO:0098857 |
membrane microdomain
|
CNR1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.08023 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
12.5964 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, F3, FLT3, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
11.8801 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.75098 |
|
[MF] GO:0043167 |
ion binding
|
ABCG2, ACHE, ALOX5, ALPL, AOX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR, XDH |
9.75098 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MPO, PTGS2, TBXAS1, TYR, XDH |
7.54386 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
7.54386 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.15634 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
7.0182 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, MMP1, MMP12, MMP2, MMP9, PPARA, PTPN1, RORC, SMAD3, TNKS |
6.89578 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
6.61331 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, PPARA, RORC, SMAD3, TEK |
6.48318 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.447 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO, PTGS2, SRC, TBXAS1 |
6.14299 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.13468 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.95438 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO, PTGS2, SRC, TBXAS1 |
5.90536 |
|
[MF] GO:0008144 |
drug binding
|
ABCG2, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, SRC, TEK |
5.80667 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HMGCR, HSD11B2, HSD17B1, IDO1, MPO, PTGS2, SRC, TBXAS1, XDH |
5.77563 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.30211 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.02207 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.02207 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.01788 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.94255 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TYR, XDH |
4.83234 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.6192 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, IDO1, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TYR, XDH |
4.59578 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1, XDH |
4.38909 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
4.38404 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, TEK |
4.34177 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, F3, FLT3, GPR35, HCAR2, HTR6, IGF1R, INSR, KDR, MET, TEK |
4.34177 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.14868 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
4.04937 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.78608 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.60943 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1, TYR |
3.58556 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.58556 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.54553 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1, TYR |
3.50714 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.43584 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.37684 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.36795 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
3.33052 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.28093 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.27922 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.23107 |
|
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
3.10474 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, XDH |
2.96017 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC |
2.95265 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HTR6 |
2.88044 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.87592 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.87592 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR |
2.76753 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.6828 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.65039 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.57795 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, XDH |
2.53266 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, XDH |
2.53241 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.5049 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.5049 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, AOX1, BCL2, CSNK2A1, EGFR, ESR1, ESR2, FLT3, HMGCR, IGF1R, KDR, MET, MMP9, PTGS2, SMAD3, TYR, XDH |
2.49899 |
|
[MF] GO:0019899 |
enzyme binding
|
AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HMGCR, HSPA1A, MET, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2 |
2.33321 |
|
[MF] GO:0008227 |
None
|
CHRM1, CHRM2, CHRM4, HTR6 |
2.33321 |
|
[MF] GO:0043168 |
anion binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MPO, NUAK1, PIM1, SRC, TEK, XDH |
2.27528 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.26382 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PTPN1 |
2.23154 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.20056 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PTPN1, SRC, TEK |
2.16285 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.11434 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.09515 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.09515 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCG2, ADORA1, AOX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, XDH |
2.08766 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.08025 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, IGF1R, INSR, KDR, TEK |
2.07929 |
|
[MF] GO:0005524 |
ATP binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.06048 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCG2, ADORA1, AOX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, MPO, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, XDH |
2.05226 |
|
[MF] GO:0051721 |
None
|
BCL2, HMGCR, PTPN1 |
2.04315 |
|
[MF] GO:0043548 |
phosphatidylinositol 3-kinase binding
|
AXL, IGF1R, INSR |
2.00889 |
