GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MAOB, MMP9, SRC, TERT |
7.51316 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.25408 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
6.95254 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, HSD17B2, IGF1R, MAOB, MMP2, MMP9, NR3C1, SRC, TYR |
6.46702 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, HCAR2, IGF1R, KDR, MET, MMP9, PIM1, SRC, TERT, TOP2A, XDH |
6.16237 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
6.16237 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FUT7, GLO1, PDE5A, PIM1, TYR, XDH |
6.16237 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, HSD11B1, HSD17B1, HSD17B2, MET |
6.09593 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B1, HSD17B1, HSD17B2 |
6.03259 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, APEX1, APP, AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MAOB, MMP2, NR3C1, SRC, TYR |
5.9116 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CSNK2A1, CYP1B1, FABP3, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PDE5A, PGR, PIM1, SRC, TERT, XDH |
5.84985 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, HCAR2, IGF1R, KDR, MET, MMP9, PIM1, SRC, TERT, TOP2A, XDH |
5.84788 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HCAR2, KDR, MET, MMP12, MMP9, PDE5A, SRC, TERT, XDH |
5.84148 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, APEX1, APP, AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MAOB, MMP2, MMP9, NR3C1, SRC, TERT, TYR |
5.84148 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HCAR2, KDR, MET, MMP12, MMP9, PDE5A, SRC, TERT, XDH |
5.84148 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GLO1, HCAR2, IGF1R, KDR, MMP9, PIM1, SRC, TERT, TOP2A, XDH |
5.68472 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, MAOB, NR3C1, SRC, TYR |
5.68472 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APEX1, APP, AR, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FLT3, MAOB, NR3C1, SRC, TYR |
5.66267 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, HCAR2, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, XDH |
5.66039 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, TYR |
5.5928 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, HCAR2, HSD11B1, HSD17B1, HSD17B2, KDR, MAOB, MET, SRC, TERT, XDH |
5.51864 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B2, KDR, MAOB, MET, MMP2, MMP9, PGR, PIM1, SRC, TERT, TOP2A, TYR |
5.45902 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MAOB, MMP1, MMP12, MMP2, MMP9, PDE5A, SRC, XDH |
5.21778 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MAOB, MET, MMP1, MMP2, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
5.20317 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, HCAR2, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, XDH |
5.04503 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, IGF1R, MAOB, MMP2, NR3C1, SRC |
5.03497 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD11B1, HSD17B1, HSD17B2 |
4.87698 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MET, MMP9, PIM1, SRC, TERT |
4.82698 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B1, HSD17B1, HSD17B2, MAOB, TYR, XDH |
4.67214 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MET, MMP9, PIM1, SRC, TERT |
4.35772 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, APEX1, AR, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, MAOB, NR3C1, SRC |
4.35772 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, APEX1, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, SRC, TERT |
4.32803 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MMP9, PIM1, SRC, TERT |
4.04536 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.79561 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
3.79561 |
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, MAOB, NR3C1, SRC |
3.78869 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.75223 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MAOB |
3.75223 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.6976 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD17B1, HSD17B2 |
3.67495 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HCAR2, HSD11B1, HSD17B1, HSD17B2 |
3.63209 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, IGF1R, KDR, PIM1, SRC |
3.57325 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, FABP3, FABP4, GLO1, HCAR2, IGF1R, KDR, MAOB, MET, MMP12, MMP9, NR3C1, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, XDH |
3.56706 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FLT3, KDR, MET, MMP12, MMP9, PDE5A, SRC, TERT, XDH |
3.55763 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, SRC, TERT, TOP2A |
3.53789 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, HCAR2, IGF1R, KDR, MAOB, MET, MMP12, MMP9, SRC, TERT |
3.53789 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, FABP3, FABP4, GLO1, IGF1R, KDR, MAOB, MET, MMP12, MMP9, NR3C1, PDE5A, PIM1, SRC, TERT, TOP2A, XDH |
3.49868 |
[BP] GO:0050665 |
hydrogen peroxide biosynthetic process
|
CYP1A1, CYP1A2, MAOB |
3.49749 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.49595 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
3.42605 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
3.41924 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD11B1, HSD17B2, KDR, SRC, TYR |
3.39725 |
[BP] GO:0010038 |
response to metal ion
|
APP, CA2, CYP1A1, CYP1A2, FABP4, MAOB, MMP9, TERT |
3.32176 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, APEX1, APP, AR, AXL, CYP1A1, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, NR3C1, SRC |
3.28817 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MAOB, MMP12, MMP2, MMP9, NR3C1, SRC, TERT, TOP2A, TYR |
3.25365 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.23302 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.19987 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.19073 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, CA9, CYP1A1, CYP1B1, FABP3, KDR, MAOB, NR3C1, SRC |
3.19073 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CYP1B1, IGF1R, MMP2, MMP9, NR3C1, SRC |
3.10467 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, PDE5A, SRC, TERT, XDH |
3.0879 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APEX1, APP, AR, CYP1A1, CYP1B1, FLT3, NR3C1, SRC |
3.08376 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HCAR2, IGF1R, KDR, MET, MMP12, MMP9, PDE5A, SRC, TERT, XDH |
3.01167 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, KDR, MET, MMP12, MMP2, MMP9, PDE5A, SRC, TERT, XDH |
2.95993 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.92851 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, HSD11B1, HSD17B2, KDR, MAOB, MMP9, PGR, PIM1, SRC, TYR |
2.87979 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CYP1B1, FLT3, KDR, MET, PDE5A, SRC, XDH |
2.86832 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.86268 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.85543 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, CA12, CA2, CA7, FABP3, FABP4, FLT3, MET, SRC, TERT |
2.84124 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, NR3C1, SRC |
2.75085 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, PDE5A, SRC, XDH |
2.73401 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1A1, CYP1B1, KDR, MAOB, SRC |
2.73401 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.73401 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, SRC |
2.72152 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.70752 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, MAOB, TYR |
2.65946 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.65143 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3 |
2.63768 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, TERT |
2.56616 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.55014 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.54923 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, MET, MMP9, SRC, TERT |
2.54051 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.54051 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AXL, CYP19A1, CYP1A2, CYP1B1, FABP4, HSD17B2, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PDE5A, PIM1, SRC, TYR |
2.47028 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD17B1, HSD17B2 |
2.44964 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.44577 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.43555 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.43555 |
[BP] GO:0048545 |
response to steroid hormone
|
AR, CA2, FLT3, MAOB, NR3C1, SRC |
2.41619 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.41529 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, SRC |
2.41403 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, CA2, CYP1B1, HCAR2, KDR, MET, MMP12, MMP9, PDE5A, PIM1, SRC, TERT |
2.37114 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.36929 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.36677 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, CYP1B1, MMP9, SRC |
2.32246 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MAOB, PDE5A, XDH |
2.32246 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.31733 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MET |
2.30794 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1 |
2.29067 |
[BP] GO:1901992 |
positive regulation of mitotic cell cycle phase transition
|
APEX1, APP, CYP1A1, TERT |
2.27263 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, GLO1, HCAR2, IGF1R, KDR, MAOB, MET, MMP12, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, XDH |
2.22088 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.21046 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, SRC |
2.2047 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.2047 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.2047 |
[BP] GO:0071383 |
None
|
AR, FLT3, NR3C1, SRC |
2.20285 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, CYP1A1, FLT3, MET, PIM1, SRC, TYR |
2.2008 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, TERT |
2.16363 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, APP, AR, FLT3, KDR, PDE5A, SRC, XDH |
2.15878 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, NR3C1, PGR, SRC |
2.13282 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.11561 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, GLO1, HCAR2, IGF1R, KDR, MAOB, MET, MMP12, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, XDH |
2.09364 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, FLT3, IGF1R, MMP2, NR3C1, SRC |
2.08752 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, NR3C1, SRC |
2.08752 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.08752 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, MAOB, XDH |
2.0619 |
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, MAOB |
2.04971 |
[BP] GO:1901989 |
None
|
APEX1, APP, CYP1A1, TERT |
2.03413 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, APP, AR, AURKB, CSNK2A1, FLT3, IGF1R, KDR, MAOB, MET, MMP12, MMP9, NR3C1, PDE5A, PGR, SRC, TERT, TOP2A, XDH |
2.01107 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, SRC |
2.01107 |
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, CYP1B1, FABP3, PDE5A, TERT, XDH |
2.01107 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3 |
2.00795 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.00795 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, CA1, CA2, CA4, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, KDR, MAOB, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
2.79555 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, GLO1, HCAR2, HSD11B1, HSD17B2, IGF1R, KDR, MAOB, MET, MMP2, NR3C2, PGR, PIM1, SRC, TERT, TYR |
1.83159 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.7072 |
[CC] GO:0097386 |
None
|
AKR1B1, APP |
1.20338 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, FLT3, GLO1, HCAR2, IGF1R, KDR, MET, MMP2, PIM1, SRC, TERT |
1.15704 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, TYR, XDH |
12.4348 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.4603 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, GLO1, HSD17B1, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, SRC, TERT, TOP2A, TYR, XDH |
9.63962 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, GLO1, HSD11B1, HSD17B1, HSD17B2, IGF1R, KDR, MAOB, MET, MMP1, MMP12, MMP2, MMP9, PDE5A, PIM1, SRC, TERT, TOP2A, TYR, XDH |
9.32008 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.25408 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.64864 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
5.9116 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, TERT, TOP2A, TYR, XDH |
5.9116 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA7, CA9, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR |
5.87959 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B1, HSD17B1, HSD17B2, MAOB, TYR, XDH |
5.66039 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PDE5A, PGR, PIM1, TERT, TOP2A, TYR, XDH |
5.61995 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.79561 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.64755 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.63904 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, HSD11B1, HSD17B1, HSD17B2, XDH |
3.35987 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.24693 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, HSD17B1, IGF1R, NR3C1 |
3.11856 |
[MF] GO:0005496 |
steroid binding
|
AR, HSD17B1, NR3C1, NR3C2, PGR |
3.10467 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, XDH |
3.03181 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
2.92851 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.86832 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.78346 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, MAOB, XDH |
2.72152 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD17B1, HSD17B2 |
2.54923 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, NR3C1, NR3C2, PGR |
2.49185 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, IGF1R, KDR, MET, PIM1, SRC, TOP2A |
2.43555 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, SRC |
2.43555 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, SRC |
2.31373 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1, MAOB, SRC, XDH |
2.28778 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, SRC |
2.22754 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, SRC |
2.20285 |
[MF] GO:0042802 |
identical protein binding
|
ACHE, APP, CSNK2A1, FLT3, IGF1R, KDR, MAOB, MET, MMP9, PGR, TERT, TOP2A, TYR, XDH |
2.16005 |
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD17B1, HSD17B2 |
2.15878 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
2.13282 |
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD17B1, HSD17B2 |
2.08752 |