GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, HSD17B1, HSD17B2, KIT, MET, PTGS2 |
8.33112 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
8.31975 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, GSK3B, HSD17B2, IDO1, IGF1R, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC, TYR |
8.07898 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, NR3C1, PTGS2, RORC, SRC, TYR |
8.01987 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FUT7, IDO1, PIM1, PTGS2, TYR, XDH |
7.61389 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CDC25B, CSNK2A1, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, KIT, MMP12, MMP2, MMP9, PGR, PIM1, PTGS2, SRC, XDH |
7.19148 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
7.14667 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
7.06445 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC, TYR |
7.06445 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2A6, TYR |
7.06445 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, GSK3B, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
7.06445 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, KIT, MMP9, PTGS2, SRC |
6.72336 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
6.70723 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
6.47678 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, IDO1, NR3C1, PTGS2, RORC, SRC, TYR |
6.47678 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
6.47183 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, DHFR |
6.34331 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
6.27909 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, HSD17B1, HSD17B2 |
6.14678 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
6.02715 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
6.02715 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7 |
5.91103 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, PIM1, SRC |
5.85067 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
5.85067 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, GSK3B, IDO1, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
5.84826 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
5.78173 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC |
5.76791 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC |
5.72321 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APP, AR, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, NR3C1, PTGS2, RORC, SRC, TYR |
5.68689 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2 |
5.48505 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2 |
5.47482 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, APP, AR, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, NR3C1, PTGS2, RORC, SRC |
5.46766 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2 |
5.30707 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, FUT7, GSK3B, HSD17B2, KDR, KIT, MET, MMP2, MMP9, PGR, PIM1, PTGS2, RORC, SRC, TYR |
5.29262 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, KIT, MET, PTGS2 |
5.13024 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
5.09094 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APP, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, GSK3B, IGF1R, KIT, MMP2, NR3C1, PTGS2, SRC |
5.03533 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
4.98084 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
4.94931 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, HSD17B2, KDR, KIT, MET, PTGS2, SRC, XDH |
4.77559 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, GSK3B, IDO1, KDR, KIT, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
4.75562 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, APP, AR, AURKB, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PTGS2, PTPN1, RORC, SRC |
4.73914 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CYP1B1, GSK3B, IGF1R, MMP2, MMP9, NR3C1, PTGS2, RORC, SRC |
4.69271 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD17B2, KDR, KIT, MMP9, PGR, PIM1, PTGS2, RORC, SRC, TYR |
4.48279 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CYP1B1, FLT3, KDR, KIT, MET, PTGS2, PTPN1, SRC, XDH |
4.27856 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2 |
4.26133 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP12, MMP2, MMP9, NR3C1, PTGS2, PTPN1, RORC, SRC, TYR |
4.10377 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2 |
4.10377 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A6 |
4.10377 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APP, AR, CYP1A1, CYP1B1, FLT3, NR3C1, PTGS2, RORC, SRC |
4.02592 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, CDC25B, CSNK2A1, FLT3, IGF1R, KDR, KIT, MMP12, MMP2, MMP9, PIM1, PTGS2 |
3.97228 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
3.95981 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AXL, CYP19A1, CYP1A2, CYP1B1, FABP4, HSD17B2, IDO1, IGF1R, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, RORC, SRC, TYR |
3.94831 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.94618 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.91048 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.90464 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.83662 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
3.82623 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.80471 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC |
3.80471 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
3.79519 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.76942 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, KIT, NR3C1, PTGS2, SRC |
3.63568 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, PTGS2 |
3.61707 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, IDO1 |
3.61707 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
3.61511 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
3.59506 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.5743 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, RORC, SRC |
3.5743 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC |
3.57118 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, FABP4, GSK3B, IGF1R, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
3.54042 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, APP, AURKB, AXL, CDC25B, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.54042 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APP, AR, FLT3, GSK3B, IGF1R, KIT, MMP2, NR3C1, PTGS2, SRC |
3.53517 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
3.53122 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, APP, AR, AXL, CDC25B, CYP19A1, CYP1A1, HSD17B2, IDO1, KIT, MMP2, MMP9, PGR, PTGS2, SRC |
3.53122 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B2, KDR, KIT, SRC, TYR |
3.47636 |
[BP] GO:0010038 |
response to metal ion
|
APP, CA2, CYP1A1, CYP1A2, FABP4, KIT, MMP9, PTGS2 |
3.43841 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
3.42438 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
3.41639 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.37886 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, APP, AURKB, AXL, CDC25B, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.29414 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, KIT, PTGS2 |
3.28312 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.27995 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.26881 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, DHFR, FABP3, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
3.25887 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, DHFR, FABP4, GSK3B, IDO1, IGF1R, MET, MMP12, MMP2, PTGS2, PTPN1, SRC, XDH |
3.17782 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC, TYR |
3.14667 |
[BP] GO:0032787 |
None
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, IDO1, PTGS2 |
3.12804 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
3.12443 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
3.12443 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, KIT, PTGS2, RORC, SRC |
3.08142 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
3.05459 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
3.05459 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
3.05459 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, RORC, SRC |
3.05459 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
3.05409 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, APP, AR, AXL, CBR1, CDC25B, CYP1A1, FABP4, FLT3, FUT7, GSK3B, KDR, KIT, MET, MMP2, MMP9, PGR, PTGS2, RORC, SRC |
3.0405 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, IDO1, PIM1, PTGS2, TYR |
2.9858 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, NR3C1, PGR, PIM1, RORC, SRC |
2.95847 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.95689 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.95689 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, APP, AR, FLT3, KDR, KIT, PTPN1, SRC, XDH |
2.95689 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.95505 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, CYP1A1, FLT3, KIT, MET, PIM1, SRC, TYR |
2.95505 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, GSK3B, IDO1, XDH |
2.9273 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.90413 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC, TYR |
2.90413 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, NR3C1, PTGS2, SRC |
2.86203 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC |
2.85967 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.85211 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, GSK3B, KIT, PGR, RORC, SRC |
2.85133 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AR, AURKB, AXL, CDC25B, CSNK2A1, CYP1A1, CYP1A2, DHFR, FLT3, FUT7, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
2.84436 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.84436 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, DHFR, TYR |
2.75648 |
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CYP1A1, KIT, PGR, PTGS2, SRC |
2.75054 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, FABP3, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.74307 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, CDC25B, CSNK2A1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.74091 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, KIT, PTGS2 |
2.71862 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, KIT, PTGS2 |
2.71862 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.71862 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
2.69798 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, APP, AR, FLT3, IGF1R, KDR, KIT, PTPN1, SRC, XDH |
2.6683 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.66665 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.66032 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, GSK3B, MET, MMP9, SRC |
2.65749 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, PTGS2 |
2.64707 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PTGS2, SRC |
2.6153 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
2.59474 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CYP1A1, CYP1B1, DHFR, FABP3, KDR, NR3C1, PTGS2, SRC |
2.59474 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.58944 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD17B1, HSD17B2 |
2.57572 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.57364 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.57364 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.53902 |
[BP] GO:0048545 |
response to steroid hormone
|
AR, CA2, FLT3, NR3C1, PTGS2, SRC |
2.52193 |
[BP] GO:0003006 |
developmental process involved in reproduction
|
AR, AXL, CDC25B, CYP19A1, HSD17B2, KIT, PGR, PTGS2, SRC |
2.5114 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.51029 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
2.5091 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CSNK2A1, DHFR, FABP4, GSK3B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.49224 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.49159 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.46473 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.43894 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
2.43729 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, CA2, CYP1B1, IDO1, KDR, KIT, MET, MMP12, MMP9, PIM1, PTGS2, SRC |
2.43462 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.43353 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, GSK3B, IDO1, SRC, XDH |
2.43317 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APP, AXL, CYP1B1, MMP9, PTGS2, SRC |
2.43101 |
[BP] GO:0050730 |
None
|
ADORA1, APP, FLT3, KIT, PTPN1, SRC |
2.42634 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, IDO1 |
2.4106 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.40095 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APP, FABP3, GSK3B, IGF1R, PTGS2, SRC |
2.39249 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
2.34937 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
2.34691 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.33015 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.33015 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.33015 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
APP, AR, AURKB, AXL, GSK3B, IGF1R, KDR, KIT, MET, MMP1, MMP9, SRC |
2.3209 |
[BP] GO:0071383 |
None
|
AR, FLT3, NR3C1, SRC |
2.31632 |
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.31632 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2 |
2.27732 |
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.27732 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, CA2, CYP1A1, KIT, MMP2, PTGS2, SRC, TYR |
2.26326 |
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.26326 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
2.25585 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, NR3C1, PGR, SRC |
2.24552 |
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, APP, AR, CDC25B, CSNK2A1, FLT3, GSK3B, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.23754 |
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.2356 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.2356 |
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, FABP4, FLT3, GSK3B, IGF1R, KIT, PTPN1, SRC |
2.2356 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
2.2356 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, APP, AR, AURKB, CDC25B, CSNK2A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KIT, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, XDH |
2.2356 |
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, APP, AR, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.23492 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, NR3C1, SRC |
2.20604 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.20604 |
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, FLT3, FUT7, KIT, MMP9, RORC |
2.20494 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, NR3C1, NR3C2, PGR, RORC |
2.19938 |
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
2.19234 |
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC |
2.18168 |
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.18168 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.18168 |
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.17782 |
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, CYP19A1, HSD17B2, KIT, SRC |
2.14122 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC |
2.13956 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.12776 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.11271 |
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, CYP1B1, FABP3, IDO1, PTGS2, XDH |
2.10581 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, SRC |
2.09636 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.09324 |
[BP] GO:0021700 |
developmental maturation
|
APP, AXL, CDC25B, MMP2, PGR |
2.08335 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.08335 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC |
2.08331 |
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, CA1, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC |
2.0775 |
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, KIT, PTPN1, SRC |
2.07698 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, HSD17B1, HSD17B2, PTGS2 |
2.07501 |
[BP] GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, MMP9, PTGS2, SRC |
2.07305 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.07062 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
2.04388 |
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APP, AR, AURKB, CSNK2A1, DHFR, FABP4, GSK3B, IGF1R, KDR, MMP12, MMP9, NR3C1, PGR, PTGS2, PTPN1, RORC, SRC, XDH |
2.04388 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, GSK3B, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, XDH |
2.03832 |
[BP] GO:1901654 |
None
|
AKR1B1, AR, CSNK2A1, NR3C1, SRC |
2.03832 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, FABP3 |
2.03052 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, DHFR, GSK3B, IDO1, KIT, MMP2, MMP9, PTGS2, PTPN1, SRC |
2.03052 |
[BP] GO:0071695 |
None
|
APP, CDC25B, MMP2, PGR |
2.0064 |
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
MMP9, PTGS2, PTPN1, SRC |
2.0064 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, CA1, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, KDR, KIT, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
3.66471 |
[CC] GO:0005829 |
cytosol
|
AKR1B1, AKR1B10, ALOX5, APP, AR, AURKB, CA1, CA2, CA7, CBR1, CDC25B, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, NR3C1, NR3C2, PGR, PIM1, PTPN1, SRC, TYR, XDH |
2.49857 |
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.04388 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.84093 |
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FLT3, HSD17B2, NR3C2, PTGS2, PTPN1 |
1.5473 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTPN1, RORC, TYR, XDH |
13.391 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
9.88994 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FLT3, FUT7, GSK3B, HSD17B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
9.62667 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
8.31975 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
7.19148 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, IDO1, PTGS2, SRC |
5.91877 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA7, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PTPN1, RORC |
5.91382 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
5.85067 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, IDO1, PTGS2, SRC |
5.7716 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
5.47482 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
5.47482 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6 |
5.47482 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.19641 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, HSD17B1, IDO1, PTGS2, SRC, XDH |
4.77559 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
4.76069 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
4.65464 |
[MF] GO:0005496 |
steroid binding
|
AR, HSD17B1, NR3C1, NR3C2, PGR, RORC |
4.44694 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, PTGS2, TYR |
4.26133 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, TYR |
4.21551 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, XDH |
4.18062 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.95981 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
3.88972 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, NR3C1, NR3C2, PGR, RORC |
3.88601 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.66471 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.59506 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2, XDH |
3.49054 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, HSD17B1, IGF1R, NR3C1 |
3.24751 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.05409 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.99291 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7 |
2.86304 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.84436 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.75655 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2 |
2.66837 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, FLT3, IGF1R, KDR, KIT, MET, NR3C1, NR3C2, PGR, RORC |
2.31632 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.31632 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PTPN1, SRC |
2.31632 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.27732 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.23906 |
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
2.2356 |
[MF] GO:0008289 |
lipid binding
|
AR, AXL, FABP3, FABP4, HSD17B1, NR3C1, NR3C2, PGR, RORC |
2.20604 |
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTPN1, SRC |
2.16424 |
[MF] GO:0005158 |
None
|
IGF1R, PTPN1, SRC |
2.14511 |
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, KDR, NR3C1 |
2.11271 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A6 |
2.0549 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.04388 |
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AURKB, AXL, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IGF1R, KDR, KIT, MET, PIM1, SRC, XDH |
2.03995 |
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DHFR, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
2.03052 |