Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1293	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2940 (nM), Ref: 19231207
TCMC565	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 680 (nM), Ref: 25765759 IC50: 3800 (nM), Ref: 25765759 IC50: 1300 (nM), Ref: 25765759
TCMC565	TCMT679	Macrophage-expressed gene 1 protein	Homo sapiens	IC50: 9100 (nM), Ref: 25765759
TCMC1123	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 1284 (nM), Ref: 20696580
TCMC1123	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 72.8 (nM), Ref: 26498393
TCMC1123	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.3 (nM), Ref: 26498393
TCMC1123	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 31.1 (nM), Ref: 26498393

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC565	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 32.9 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC565	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2591	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 6.25 (ug/ml), Ref: 8864235
TCMC2591	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 0.78 (ug/ml), Ref: 8864235
TCMC2591	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 1.56 (ug/ml), Ref: 8864235
TCMC2591	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 0.39 (ug/ml), Ref: 8864235
TCMC2591	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 0.78 (ug/ml), Ref: 8864235
TCMC1123	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC1123	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 25 (ug/ml), Ref: 15679330
TCMC2719	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 100 (ug/ml), Ref: MIC: 100 (ug/ml), Ref: 24893224
TCMC2722	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 19 (ug/ml), Ref: 25304895
TCMC2724	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 1.56 (ug/ml), Ref: 20675131 MIC: 3.13 (ug/ml), Ref: 18038969
TCMC2725	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 25 (ug/ml), Ref: 22975593 MIC: 50 (ug/ml), Ref: 16499319
TCMC2726	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 1.56 (ug/ml), Ref: 22975593 MIC: 3.13 (ug/ml), Ref: 16499319
TCMC2719	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 25 (ug/ml), Ref: MIC: 50 (ug/ml), Ref: 16441087
TCMC2719	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 25 (ug/ml), Ref: 21115251
TCMC2719	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 12.5 (ug/ml), Ref: 10.6019/CHEMBL1201861
TCMC2726	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 3.13 (ug/ml), Ref: 10.6019/CHEMBL1201861
TCMC2725	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 12.5 (ug/ml), Ref: 10.6019/CHEMBL1201861
TCMC2722	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 20 (ug/ml), Ref: 10.1039/C5MD00247H
TCMC2743	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 0.39 (ug/ml), Ref: 16279794 MIC: 0.39 (ug/ml), Ref: 16441079
TCMC2724	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 3.13 (ug/ml), Ref: 18817444 MIC: 3.13 (ug/ml), Ref: 23046382
TCMC2743	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 1.56 (ug/ml), Ref: 18817444 MIC: 1.56 (ug/ml), Ref: 18687007
TCMC2726	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 3.13 (ug/ml), Ref: 23046382 MIC: 3.13 (ug/ml), Ref: 18687007
TCMC2725	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 100 (ug/ml), Ref: 23046382 MIC: 100 (ug/ml), Ref: 12444693
TCMC2719	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 12.5 (ug/ml), Ref: 16180826
TCMC2725	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 12.5 (ug/ml), Ref: 11858748
TCMC2726	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 0.39 (ug/ml), Ref: 16417306
TCMC2743	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 0.2 (ug/ml), Ref: 17279797
TCMC2724	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 0.39 (ug/ml), Ref: 17279797
TCMC2722	TCMT1251	Candida albicans	Candida albicans	IC50: 5.5 (ug/ml), Ref: 20405844
TCMC2725	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 25 (ug/ml), Ref: 24613627
TCMC2743	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 1.56 (ug/ml), Ref: 11575965
TCMC2724	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 3.13 (ug/ml), Ref: 11575965
TCMC2724	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 3.13 (ug/ml), Ref: 17958396
TCMC2743	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 0.78 (ug/ml), Ref: 17958396
TCMC2726	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 6.25 (ug/ml), Ref: 17958396
TCMC2764	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 25 (ug/ml), Ref: 8487254 MIC: 25 (ug/ml), Ref: 18180357
TCMC2765	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 0.78 (ug/ml), Ref: 19931461 MIC: 1.56 (ug/ml), Ref: 26214125
TCMC2764	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 12.5 (ug/ml), Ref: 19931461 MIC: 12.5 (ug/ml), Ref: 26214125
TCMC2770	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 21 (ug/ml), Ref: 10.1007/s00044-012-0342-1
TCMC2770	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 10 (ug/ml), Ref: PubChem BioAssay data set
TCMC2764	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 3.13 (ug/ml), Ref: 16933872
TCMC2765	TCMT1210	Streptococcus sobrinus	Streptococcus sobrinus	MIC: 3.13 (ug/ml), Ref: 23434030 MIC: 0.78 (ug/ml), Ref: 18180357
TCMC2765	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 0.39 (ug/ml), Ref: 14510611
TCMC2770	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 8 (ug/ml), Ref: 11356101
TCMC2770	TCMT1251	Candida albicans	Candida albicans	IC50: 10 (ug/ml), Ref: 11356101
TCMC2764	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 3.13 (ug/ml), Ref: 19222165
TCMC2765	TCMT1370	Prevotella melaninogenica	Prevotella melaninogenica	MIC: 1.56 (ug/ml), Ref: 20805391
TCMC2765	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 6.25 (ug/ml), Ref: 18077425
TCMC2764	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 6.25 (ug/ml), Ref: 18077425