Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT107 | Glutamate receptor ionotropic kainate 2 | Homo sapiens |
Ki: 1106 (nM), Ref: 10821708 |
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TCMT108 | Glutamate receptor ionotropic, AMPA 1 | Homo sapiens |
Ki: 1360 (nM), Ref: 9357531 |
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TCMT109 | Glutamate receptor ionotropic, AMPA 2 | Homo sapiens |
Ki: 940 (nM), Ref: 9357531 |
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TCMT110 | Glutamate receptor ionotropic, AMPA 4 | Homo sapiens |
Ki: 868 (nM), Ref: 9357531 |
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TCMT111 | Glutamate receptor ionotropic kainate 5 | Homo sapiens |
Ki: 701 (nM), Ref: 9357531 |
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TCMT660 | Metabotropic glutamate receptor 8 | Homo sapiens |
IC50: 5.7 (nM), Ref: 15603952 |
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TCMT112 | Adenosine A3 receptor | Homo sapiens |
IC50: 613 (nM), Ref: 16250647 |
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TCMT653 | Metabotropic glutamate receptor 1 | Homo sapiens |
Ki: 250 (nM), Ref: 17725337 Ki: 570 (nM), Ref: 19042134 Ki: 1584.89 (nM), Ref: 10.1039/C1MD00186H |
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TCMT654 | Metabotropic glutamate receptor 5 | Homo sapiens |
Ki: 390 (nM), Ref: 17725337 Ki: 1160 (nM), Ref: 19042134 Ki: 4677.35 (nM), Ref: 10.1039/C1MD00186H |
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TCMT657 | Metabotropic glutamate receptor 4 | Homo sapiens |
Ki: 2400 (nM), Ref: 17725337 Ki: 1400 (nM), Ref: 19042134 Ki: 3235.94 (nM), Ref: 10.1039/C1MD00186H |
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TCMT655 | Metabotropic glutamate receptor 2 | Homo sapiens |
Ki: 6400 (nM), Ref: 19042134 Ki: 1819.7 (nM), Ref: 10.1039/C1MD00186H |
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TCMT664 | Excitatory amino acid transporter 3 | Homo sapiens |
Ki: 51 (nM), Ref: 18578477 |
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TCMT656 | Metabotropic glutamate receptor 3 | Homo sapiens |
Ki: 57.54 (nM), Ref: 10.1039/C1MD00186H |
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TCMT38 | Dopamine D2 receptor | Homo sapiens |
Ki: 1.89 (nM), Ref: 10465538 Ki: 759 (nM), Ref: 10465538 Ki: 572 (nM), Ref: 8893836 Ki: 20 (nM), Ref: 10691700 Ki: 17 (nM), Ref: 10691700 Ki: 450 (nM), Ref: 18834111 Ki: 360 (nM), Ref: 18834111 Ki: 2100 (nM), Ref: 20155917 Ki: 2.9 (nM), Ref: 20155917 Ki: 2100 (nM), Ref: 22846798 Ki: 422 (nM), Ref: 23134120 Ki: 110 (nM), Ref: 23428965 Ki: 190 (nM), Ref: 23428965 Ki: 2100 (nM), Ref: 23727194 Ki: 8 (nM), Ref: 24138311 Ki: 8.73 (nM), Ref: 27035329 Ki: 3690 (nM), Ref: 27035329 Ki: 48 (nM), Ref: 27132867 |
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TCMT651 | Dopamine D3 receptor | Homo sapiens |
Ki: 13.2 (nM), Ref: 8893836 Ki: 50 (nM), Ref: 10691700 Ki: 240 (nM), Ref: 18834111 Ki: 72 (nM), Ref: 18834111 Ki: 15 (nM), Ref: 22846798 Ki: 20 (nM), Ref: 23134120 Ki: 21 (nM), Ref: 23428965 Ki: 15 (nM), Ref: 23727194 Ki: 7.58 (nM), Ref: 27035329 Ki: 293 (nM), Ref: 27035329 |
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TCMT635 | Dopamine transporter | Homo sapiens |
Ki: 6400 (nM), Ref: 14592523 IC50: 460 (nM), Ref: 14592523 |
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TCMT634 | Norepinephrine transporter | Homo sapiens |
IC50: 6.63 (nM), Ref: 14592523 |
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TCMT648 | Dopamine D4 receptor | Homo sapiens |
Ki: 1.2 (nM), Ref: 10691700 Ki: 6.2 (nM), Ref: 18834111 Ki: 8.9 (nM), Ref: 23428965 |
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TCMT316 | Melatonin receptor 1A | Homo sapiens |
Ki: 7100 (nM), Ref: 10.1016/S0960-894X(97)00444-7 |
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TCMT317 | Melatonin receptor 1B | Homo sapiens |
Ki: 9100 (nM), Ref: 10.1016/S0960-894X(97)00444-7 |
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TCMT27 | Dopamine D1 receptor | Homo sapiens |
Ki: 4470 (nM), Ref: 23134120 |
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TCMT8 | Lysine-specific demethylase 4D-like | Homo sapiens |
IC50: 3000 (nM), Ref: 10.1039/C1MD00199J |
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 5200 (nM), Ref: 18558747 |
