Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC1429	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2700 (nM), Ref: 17378609
TCMC1429	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 1050 (nM), Ref: 18533708
TCMC1429	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 360 (nM), Ref: 18533708
TCMC1429	TCMT187	Androgen Receptor	Homo sapiens	IC50: 9700 (nM), Ref: 19592245
TCMC1429	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 716 (nM), Ref: 20696580
TCMC1429	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 632 (nM), Ref: 20696580
TCMC1429	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 47 (nM), Ref: 20696580
TCMC1429	TCMT223	Aldose reductase	Homo sapiens	IC50: 10000 (nM), Ref: 22261024
TCMC1429	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 2320 (nM), Ref: 23411073
TCMC1429	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 9640 (nM), Ref: 23656512
TCMC1429	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 10000 (nM), Ref: 26322379
TCMC1429	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9525.7 (nM), Ref: 26498393
TCMC1429	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 25 (nM), Ref: 26498393
TCMC1429	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 145.9 (nM), Ref: 26498393
TCMC1429	TCMT159	Tyrosinase	Homo sapiens	IC50: 1000 (nM), Ref: 26841168
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC2025	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2025.72 (nM), Ref:
TCMC949	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 19911821
TCMC949	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 48 (nM), Ref: 19911821
TCMC949	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9100 (nM), Ref: 19911821
TCMC949	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3300 (nM), Ref: 19911821
TCMC949	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 2000 (nM), Ref: 19911821
TCMC949	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 5200 (nM), Ref: 19911821
TCMC949	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9400 (nM), Ref: 19911821
TCMC949	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6800 (nM), Ref: 19911821
TCMC949	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 5600 (nM), Ref: 19911821
TCMC949	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270
TCMC949	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270
TCMC1786	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3900 (nM), Ref: 16580200 IC50: 7600 (nM), Ref: 18798681 IC50: 4200 (nM), Ref: 19702283 IC50: 3840 (nM), Ref: 22044245 IC50: 5600 (nM), Ref: 22690646 IC50: 9500 (nM), Ref: 21453996 Ki: 6000 (nM), Ref: 21453996 IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2600 (nM), Ref: 23357636 IC50: 1100 (nM), Ref: 23434422 IC50: 3020 (nM), Ref: 23942421 IC50: 2010 (nM), Ref: 24090912 IC50: 1900 (nM), Ref: 24684845 IC50: 3020 (nM), Ref: 25497963 IC50: 9500 (nM), Ref: 25264584 Ki: 6000 (nM), Ref: 25264584 IC50: 1030 (nM), Ref: 25595683 IC50: 1170 (nM), Ref: 25600405 IC50: 3020 (nM), Ref: 25872983 IC50: 1000 (nM), Ref: 26083682 IC50: 1536 (nM), Ref: 26100442 IC50: 700 (nM), Ref: 26115570 IC50: 700 (nM), Ref: 26253631 IC50: 1536 (nM), Ref: 26481657 IC50: 730 (nM), Ref: 26711144 IC50: 3020 (nM), Ref: 26774579 IC50: 1536 (nM), Ref: 27123900
TCMC1786	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 4000 (nM), Ref: 21561086 Ki: 3560 (nM), Ref: 21561086 Ki: 660 (nM), Ref: 21561086 Ki: 940 (nM), Ref: 21561086 Ki: 160 (nM), Ref: 21561086 Ki: 72 (nM), Ref: 21561086 IC50: 90 (nM), Ref: 21561086
TCMC1786	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 4230 (nM), Ref: 24684845 IC50: 4440 (nM), Ref: 25497963 IC50: 5460 (nM), Ref: 26100442 IC50: 5460 (nM), Ref: 26481657 IC50: 5460 (nM), Ref: 27123900
TCMC1786	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 980 (nM), Ref: 25497963
TCMC837	TCMT690	Histone deacetylase 3	Homo sapiens	IC50: 9000 (nM), Ref: 21874153
TCMC1594	TCMT197	Phosphodiesterase 4D	Homo sapiens	IC50: 2900 (nM), Ref: 22483586 IC50: 2910 (nM), Ref: 26473791
TCMC1594	TCMT698	Phosphodiesterase 4B	Homo sapiens	IC50: 4500 (nM), Ref: 22483586
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC2025	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 5600 (nM), Ref: 23353736
TCMC2003	TCMT82	Estrogen receptor alpha	Homo sapiens	Ki: 785 (nM), Ref: 15634023
TCMC2003	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 2840 (nM), Ref: 16814546 IC50: 4120 (nM), Ref: 18063374 IC50: 625 (nM), Ref:
TCMC2003	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 996 (nM), Ref: 17604631 IC50: 750 (nM), Ref: 20527891 IC50: 996 (nM), Ref: 26850006
TCMC2003	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 960 (nM), Ref: 19265439 IC50: 450 (nM), Ref: 20036559 IC50: 450 (nM), Ref: 20356739 IC50: 960 (nM), Ref: 21261296 IC50: 6900 (nM), Ref: 23953689 Ki: 88 (nM), Ref: 23953689 IC50: 1400 (nM), Ref: 26854376 IC50: 913 (nM), Ref: 26854376
TCMC2003	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2210 (nM), Ref: 20674354
TCMC2003	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2770 (nM), Ref: 20674354
TCMC2003	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 9090 (nM), Ref: 20674354
TCMC2003	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4470 (nM), Ref: 20674354
TCMC2003	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4750 (nM), Ref: 20674354
TCMC2003	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4640 (nM), Ref: 20674354
TCMC2003	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8070 (nM), Ref: 20674354
TCMC2003	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4350 (nM), Ref: 20674354
TCMC2003	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 810 (nM), Ref: 20674354
TCMC2003	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 950 (nM), Ref: 20674354
TCMC2003	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4090 (nM), Ref: 20674354
TCMC2003	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 830 (nM), Ref: 20674354
TCMC2003	TCMT729	PI3-kinase p110-alpha subunit	Homo sapiens	IC50: 250 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT730	PI3-kinase p110-beta subunit	Homo sapiens	IC50: 500 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4100 (nM), Ref: 27190601 IC50: 2600 (nM), Ref: 27190601
TCMC1986	TCMT223	Aldose reductase	Homo sapiens	IC50: 150 (nM), Ref: 18165015 IC50: 2000 (nM), Ref: 22261024
TCMC2025	TCMT359	Tyrosine-protein kinase FYN	Homo sapiens	IC50: 1300 (nM), Ref: 17315853 IC50: 3600 (nM), Ref: 17315853 Ki: 7500 (nM), Ref: 17315853
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1428	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 509 (nM), Ref: 20696580
TCMC1428	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 88 (nM), Ref: 20696580
TCMC1428	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC1734	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	Ki: 3430 (nM), Ref: 19097799
TCMC1734	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 4960 (nM), Ref: 18533708
TCMC1734	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 2.9 (nM), Ref: 20413308 IC50: 230 (nM), Ref: 22115839 IC50: 230 (nM), Ref: 23142320 IC50: 1200 (nM), Ref: 23994869 IC50: 3300 (nM), Ref: 24074257 IC50: 1200 (nM), Ref: 24992702 IC50: 5100 (nM), Ref: 27155469 IC50: 1000 (nM), Ref: 27155469
TCMC1734	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 3656 (nM), Ref: 20696580
TCMC1734	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 79.5 (nM), Ref: 26498393
TCMC1734	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.3 (nM), Ref: 26498393
TCMC1734	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 44.3 (nM), Ref: 26498393
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC1892	TCMT508	Tyrosine-protein kinase SYK	Homo sapiens	IC50: 10000 (nM), Ref: 23917087
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC2137	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 5750 (nM), Ref: 22658537
TCMC2137	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9098.2 (nM), Ref: 26498393
TCMC2137	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 493.1 (nM), Ref: 26498393
TCMC2137	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 32.5 (nM), Ref: 26498393
TCMC1063	TCMT277	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Ki: 1430 (nM), Ref: 23396419 Ki: 4550 (nM), Ref: 23396419 Ki: 8290 (nM), Ref: 23396419 Ki: 1030 (nM), Ref: 23396419
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1429	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 16.77 (ug/ml), Ref: 20116898
TCMC1786	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 10 (ug/ml), Ref: 10691716
TCMC1986	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 75.2 (ug/ml), Ref: 9461665
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1429	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2431	TCMT1247	Human herpesvirus 1	Human herpesvirus 1	MIC: 20 (ug/ml), Ref: 12398535
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC1786	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC1594	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 25461329
TCMC1594	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 25461329 MIC: 12.5 (ug/ml), Ref: 25461329
TCMC1594	TCMT1246	Escherichia coli	Escherichia coli	MIC: 78 (ug/ml), Ref: 25461329
TCMC1594	TCMT1289	Shigella dysenteriae	Shigella dysenteriae	MIC: 78 (ug/ml), Ref: 25461329
TCMC1594	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 78 (ug/ml), Ref: 25461329
TCMC2003	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1251	Candida albicans	Candida albicans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12036362
TCMC2003	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753
TCMC2003	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 25 (ug/ml), Ref: 20022753
TCMC1986	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 17.7 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC2483	TCMT1247	Human herpesvirus 1	Human herpesvirus 1	MIC: 20 (ug/ml), Ref: 12398535
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1428	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1428	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 25 (ug/ml), Ref: 12762812
TCMC1428	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 32.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 26 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1734	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 92.24 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2025	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC2025	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC2025	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC1892	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC1892	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC2025	TCMT1246	Escherichia coli	Escherichia coli	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC2137	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1063	TCMT1251	Candida albicans	Candida albicans	MIC: 1.56 (ug/ml), Ref: 3373231 MIC: 3.12 (ug/ml), Ref: 3373231 MIC: 6.25 (ug/ml), Ref: 3373231 MIC: 2 (ug/ml), Ref: 15921418
TCMC1063	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 3373231 MIC: 1 (ug/ml), Ref: 15921418
TCMC1063	TCMT1243	Aspergillus flavus	Aspergillus flavus	MIC: 100 (ug/ml), Ref: 3373231
TCMC1063	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 32 (ug/ml), Ref: 15921418
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522