TCM Putative Target References: TCMH232


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2196
TCMT30 Cyclooxygenase-2 Homo sapiens IC50: 64 (nM), Ref: 22819942
IC50: 64 (nM), Ref: 23146282
TCMC2196
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 150 (nM), Ref: 22819942
TCMC2196
TCMT336 Indoleamine 2,3-dioxygenase Homo sapiens IC50: 53.7 (nM), Ref: 24099220
IC50: 7150 (nM), Ref: 24099220
Ki: 4810 (nM), Ref: 24099220
TCMC2063
TCMT646 Serotonin 5a (5-HT5a) receptor Homo sapiens Ki: 126 (nM), Ref: 12825922
IC50: 180 (nM), Ref: 18983139
Ki: 110 (nM), Ref: 18983139
IC50: 184 (nM), Ref: 18588282
Ki: 170 (nM), Ref: 21726069
IC50: 280 (nM), Ref: 23582449
Ki: 82 (nM), Ref: 23466604
IC50: 160 (nM), Ref: 23466604
IC50: 180 (nM), Ref: 26988801
TCMC2063
TCMT315 Serotonin 6 (5-HT6) receptor Homo sapiens Ki: 65 (nM), Ref: 12825922
Ki: 100 (nM), Ref: 15357994
IC50: 200 (nM), Ref: 18983139
Ki: 93 (nM), Ref: 18983139
IC50: 262 (nM), Ref: 18588282
IC50: 27.5 (nM), Ref: 20170099
Ki: 84 (nM), Ref: 21726069
Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8
IC50: 180 (nM), Ref: 23582449
Ki: 50 (nM), Ref: 23466604
IC50: 100 (nM), Ref: 23466604
Ki: 33 (nM), Ref: 24805037
Ki: 33 (nM), Ref: 25557493
IC50: 120 (nM), Ref: 26988801
Ki: 100 (nM), Ref: 26996373
TCMC2063
TCMT160 Serotonin 7 (5-HT7) receptor Homo sapiens Ki: 8.1 (nM), Ref: 12825922
IC50: 0.61 (nM), Ref: 18983139
Ki: 0.22 (nM), Ref: 18983139
IC50: 2.55 (nM), Ref: 12713409
IC50: 1.5 (nM), Ref: 18588282
Ki: 0.13 (nM), Ref: 21726069
IC50: 0.49 (nM), Ref: 23582449
Ki: 0.11 (nM), Ref: 23466604
IC50: 0.29 (nM), Ref: 23466604
Ki: 1.4 (nM), Ref: 24763360
Ki: 0.8 (nM), Ref: 24805037
Ki: 0.8 (nM), Ref: 25557493
IC50: 0.25 (nM), Ref: 26988801
TCMC2063
TCMT37 Serotonin 2a (5-HT2a) receptor Homo sapiens Ki: 14 (nM), Ref: 15081042
Ki: 8.2 (nM), Ref: 16392816
Ki: 14 (nM), Ref: 16257207
Ki: 120 (nM), Ref: 18468904
Ki: 160 (nM), Ref: 18468904
Ki: 130 (nM), Ref: 18468904
Ki: 150 (nM), Ref: 18468904
Ki: 320 (nM), Ref: 11975483
Ki: 690 (nM), Ref: 17067154
Ki: 323.59 (nM), Ref: 23301527
Ki: 320 (nM), Ref: 23301527
TCMC2063
TCMT313 Serotonin 2b (5-HT2b) receptor Homo sapiens Ki: 12 (nM), Ref: 15081042
Ki: 13 (nM), Ref: 12954071
Ki: 13 (nM), Ref: 16392816
Ki: 12 (nM), Ref: 16257207
Ki: 13.49 (nM), Ref: 24582985
TCMC2063
TCMT314 Serotonin 2c (5-HT2c) receptor Homo sapiens Ki: 6.9 (nM), Ref: 15081042
Ki: 8.3 (nM), Ref: 12954071
Ki: 8.3 (nM), Ref: 16392816
Ki: 6.9 (nM), Ref: 16257207
Ki: 130 (nM), Ref: 11975483
Ki: 20 (nM), Ref: 17067154
Ki: 79.43 (nM), Ref: 23301527
Ki: 79 (nM), Ref: 23301527
TCMC2063
TCMT815 Serotonin 1d (5-HT1d) receptor Homo sapiens Ki: 5.5 (nM), Ref: 8071931
Ki: 0.5 (nM), Ref: 18507369
TCMC2063
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 2.5 (nM), Ref: 7658447
IC50: 1.2 (nM), Ref: 12954071
Ki: 1.259 (nM), Ref: 18433113
Ki: 10000 (nM), Ref: 18433113
Ki: 0.62 (nM), Ref: 22748706
Ki: 0.9 (nM), Ref: 23332346
Ki: 9.5 (nM), Ref: 24161678
Ki: 2.08 (nM), Ref: 25128671
TCMC2063
TCMT112 Adenosine A3 receptor Homo sapiens IC50: 79 (nM), Ref: 16250647
TCMC2063
TCMT816 Serotonin 1b (5-HT1b) receptor Homo sapiens Ki: 1.1 (nM), Ref: 18507369
IC50: 29 (nM), Ref: 18983139
Ki: 18 (nM), Ref: 18983139
Ki: 14 (nM), Ref: 21726069
IC50: 12 (nM), Ref: 23582449
Ki: 4 (nM), Ref: 23466604
IC50: 6.5 (nM), Ref: 23466604
TCMC2063
TCMT817 Serotonin 4 (5-HT4) receptor Homo sapiens Ki: 1049 (nM), Ref: 19334715
Ki: 500 (nM), Ref: 17067154
Ki: 29.51 (nM), Ref: 19223092
Ki: 109.65 (nM), Ref: 19223092
TCMC2063
TCMT645 Serotonin 1e (5-HT1e) receptor Homo sapiens Ki: 10.72 (nM), Ref: 24365159
Ki: 11 (nM), Ref: 24365159

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2063
TCMT1086 Isocitrate lyase Candida albicans IC50: 53 (ug/ml), Ref: 21035332
TCMC2196
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 10 (ug/ml), Ref: 22819942
MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 1 (ug/ml), Ref: 23360475
MIC: 1 (ug/ml), Ref: 26253635
TCMC2196
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 6 (ug/ml), Ref: 26253635